🎤 Presenter: Christopher Freye (Los Alamos National Laboratory)💾 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_1_Freye_10783a9cf3.pdf">PDF presentation</a><h3>Abstract</h3>Two-dimensional gas chromatography (<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=2">GC×GC</a>) when coupled with mass spectrometry (MS) especially high-resolution mass spectrometry (HRMS) provides the ideal technique to discover minute chemical changes. However, GC×GC analyses result in extremely large datasets (GBs of information) wherein the statistically significant chemical changes are buried within the background chemical matrix. To combat these issues, many chemometric techniques have been developed or applied. Recently we introduced a new chemometric technique for GC-MS termed alteration analysis (ALA) and two-dimensional correlation (2DCOR) which can be used to discover statistically significant chemical changes across a series of chromatograms and understand the relationship between the statistically relevant changes. ALA generates three sets of information, the basic alteration map (BAM) which is the magnitude of the change, the synchronous alteration map (SAM) which describes the linear change, and the asynchronous alteration map (AAM) which describes the non-linear change. 2DCOR can then be used to understand the relationship between the chemical changes but 2DCOR can also resolve the sequence of the changes. A workflow for GC×GC-MS will be demonstrated. Special attention will be given to what differentiates the GC×GC work flow from GC for both the ALA and 2DCOR.<h3>Video Transcription</h3>The presentation focuses on how advanced mathematical and chemometric methods can be used to extract meaningful information from highly complex chromatographic data, especially in multidimensional chromatography coupled with mass spectrometry (GC×GC-MS, LC-MS).<h4>Why traditional data analysis falls short</h4>Modern multidimensional chromatography generates extremely large datasets, often containing billions of data points. Visual inspection, peak tables, or classical identification-based workflows are impractical—especially when:<ul><li>Samples are highly complex (e.g. petroleum, metabolomics, high explosives)</li><li>Most compounds are unknown unknowns</li><li>The key question is not what the compounds are, but whether samples differ and how</li></ul>Program managers and decision-makers are primarily interested in detecting statistically significant changes, not exhaustive compound identification.<h4>Introduction of Alteration Analysis (ALA)</h4>To address subtle, trend-based changes across series of chromatograms, the speaker introduces Alteration Analysis (ALA), a chemometric approach adapted from spectroscopy and applied to chromatography.ALA quantitatively evaluates how individual data points change across multiple samples, allowing detection of:<ul><li>Extremely subtle trends</li><li>Overlapping peaks</li><li>Changes hidden in noise or baseline interference</li></ul>Key ALA outputs include:<ul><li>BAM (Basic Alteration Map): magnitude of change</li><li>SAM (Systematic Alteration Map): linear changes</li><li>AM (Alteration Map): nonlinear changes</li></ul>Even changes as small as 1% per sample can be detected reliably, including peaks that are heavily overlapped.<h4>Beyond detection: understanding relationships with 2D Correlation</h4>Once statistically significant changes are identified, two-dimensional correlation analysis (2D-COR) is used to understand relationships between changing compounds, including:<ul><li>Whether compounds are correlated or anti-correlated</li><li>The sequence of changes over time (which changes happen first)</li></ul>This is especially critical for degradation and aging studies, where intermediate species may appear and disappear before the final state—information that traditional methods like Fisher ratio or PCA often miss.<h4>Solving GC×GC challenges with tiling</h4>GC×GC data introduces additional challenges due to:<ul><li>Peak misalignment</li><li>Exponential data growth during correlation calculations</li></ul>The presenter explains how tile-based approaches reduce data dimensionality, overcome alignment issues, and make ALA and 2D correlation computationally feasible—even for massive GC×GC-MS datasets.<h4>Real-world application: explosive aging studies</h4>The methodology was applied to aging and decomposition of high explosives, where:<ul><li>Over 250 chemical changes were identified</li><li>Many intermediate species would have been missed using traditional comparisons</li><li>ALA combined with 2D correlation enabled reconstruction of degradation pathways</li><li>The most significant change was not necessarily the first change, a critical insight for risk assessment and stability studies</li></ul><h4>Key takeaway</h4>By combining Alteration Analysis and 2D correlation, the approach:<ul><li>Detects statistically guaranteed chemical changes</li><li>Handles subtle, overlapped, and noisy signals</li><li>Determines magnitude, type, interrelationships, and order of changes</li><li>Shifts chromatographic data analysis from identification-driven to decision-driven</li></ul>This math-driven workflow enables faster, more reliable interpretation of complex chromatographic datasets and provides actionable insights for applications such as explosive aging, pharmaceutical degradation, and complex mixture analysis.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote>

Discovery analysis for GCxGC trends using alteration and 2D correlation (Chris Freye, MDCW 2026)

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 9th February 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you technical note by Agilent Technologies, presentation by MDCW / University of Copenhagen and application notes by Shimadzu and Thermo Fisher Scientific!<h3>1. Agilent Technologies: What Causes Spots on <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=19&amp;manufacturerItems=1&amp;search=PLOT">PLOT Columns</a>? Will It Affect the Performance of the Column?</h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/te_what_causes_spots_plot_columns_affecting_performance_5994_8775en_agilent_3b7180512a.pdf">Full PDF for download</a></li></ul>Spots on porous layer open tubular (PLOT) columns are caused by small voids in the stationary phase coating inside the tube. These spots are areas where there is an uneven coating or lack of phase. It is normal to find some voids in the phase coating of PLOT columns. The stationary phase in PLOT columns is an opaque, solid, and porous material. In many Agilent PLOT columns such as the GS-Alumina phases, molecular sieves, porous polymers (Q and U), and the GS-OxyPLOT, the stationary phase is visible as a white powder. For many PLOT columns, the stationary phase fill solution is a viscous suspension of particles that are less than 10 microns in diameter. The phase is coated using a dynamic process in which a plug of fill solution is pushed through the tubing, and the plug’s speed and viscosity determines the thickness of the stationary phase layer. Once the PLOT’s stationary phase is deposited, it is held in place by electrostatic charge, chemical interactions between particles, and/or binding agents. In wall‑coated open tubular (WCOT) columns, stationary phases such as polysiloxanes or polyethylene glycols are immobilized by chemical bonding to the glass surface and cross-linking between polymer strands. Because this type of bonding and cross‑linking is not possible with PLOT phases, the result is a stationary phase layer that is both fundamentally different and inherently less stable in PLOT columns than in WCOT&nbsp;columns.<h3>2. MDCW / University of Copenhagen: One-shot tensor decomposition of full-scale GC×GC-VUV datasets for resolving petrochemical groups</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_17_Schneide_67c8ff7866.pdf">Full PDF for download</a></li></ul>The presentation introduces a novel all-samples-at-once, shift-invariant tri-linear tensor decomposition approach for the analysis of full-scale <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?search=GC%C3%97GC-VUV">GC×GC-VUV</a> datasets, aimed at resolving and quantifying petrochemical groups. Traditional template-based or pixel-based methods struggle with retention-time shifts and co-eluting compounds, often requiring manual intervention and prior chemical knowledge. The proposed approach leverages the intrinsic low-rank structure of GC×GC-VUV data to enable robust, automated group-level analysis across multiple samples simultaneously.At the core of the method is a shift-invariant tri-linear model, conceptually related to PARAFAC and multivariate curve resolution, but extended using frequency-domain (FFT-based) modeling to explicitly account for chromatographic peak shifts. By decomposing the entire dataset in one step, the model provides accurate estimates of peak landscapes, VUV spectra, and relative peak areas, while remaining agnostic to retention-time variability. Importantly, the approach requires only a small number of tunable parameters, making it practical for routine use.The method was demonstrated on a case study involving 14 petrochemical gas-oil samples, including straight-run, hydrotreated, hydroconverted, coker, and light cycle oils. Extracted VUV spectra showed excellent agreement with reference spectra from a VUV spectral database, enabling confident assignment of components to chemical groups such as saturates, olefins, and mono- to poly-aromatics. Quantitative results exhibited high repeatability (RSD typically 3–9%) and strong correlation with established template-based reference methods.Overall, the work demonstrates that one-shot, shift-invariant tensor decomposition provides a powerful and scalable alternative to conventional GC×GC data-analysis strategies. By combining chemical interpretability, robustness to chromatographic shifts, and strong quantitative performance, the approach opens new opportunities for automated, high-confidence group-level analysis of complex petrochemical samples and beyond.<h3>3. Shimadzu: Py-Screener Ver. 3: Simultaneously Test for Substances Regulated Under RoHS, TSCA, and POPs</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00949_en_4754e50164.pdf">Full PDF for download</a></li></ul><h5>User Benefits</h5><ul><li>In just one analysis, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=3&amp;search=Py-Screener">Py-Screener</a> Ver. 3 can determine levels of phthalate esters, brominated flame retardants (PBBs, PBDEs), PIP (3:1), UV-328, dechlorane plus (DP), short-chain chlorinated paraffins (SCCPs), and medium-chain chlorinated paraffins (MCCPs).&nbsp;</li><li>It can also test for SCCPs and MCCPs by electron ionization (EI) instead of negative chemical ionization (NCI).&nbsp;</li><li>PIP (3:1), UV-328, DP, and SCCPs and MCCPs can be screened without the need for corresponding reference materials.</li></ul>Countries and regulatory bodies worldwide are introducing increasingly stringent regulations on the chemical substances used in electronic devices and industrial products. The RoHS Directive and REACH regulations in the EU, the Toxic Substances Control Act (TSCA) in the USA, and the Stockholm Convention on Persistent Organic Pollutants (POPs) are also targeting an increasingly broad range of substances. Therefore, manufacturers are required to accurately identify regulated substances in their products and comply with each regulation. While Py-Screener Ver. 2 can screen for seven phthalate esters and brominated flame retardants, including substances regulated under the RoHS Directive, version 3 can also screen for PIP (3:1), which is regulated under the TSCA, as well as UV328, DP, and SCCPs and MCCPs , which are regulated under the Stockholm Convention on POPs. A list of supported substances isshown in Table 1. This article introduces the simultaneous analysis of multiple regulated substances and a case study of testing specific regulated substances in samples, using Py-Screener Ver. 3.<h4>Analysis Process</h4>Py-Screener Ver. 3 can determine levels of phthalate esters and brominated flame retardants contained in products in accordance with the international analytical standards IEC62321-8 and IEC62321-3-3. It can also test for specific regulated substances (Table 1) under the same conditions and in the same analysis. In this test, background intensity and instrument sensitivity (S/N) were verified before analyzing samples. These parameters are prescribed by IEC62321-8 to ensure the accuracy of the methods used. Background intensity and instrument sensitivity were determined using a reference material (PN: 225-31003- 91) *1 that consisted of a plastic sheet that was spiked with seven phthalate esters. The results met the criteria for both parameters.The testing workflow is shown in Fig. 1. Before testing samples, calibration curves were prepared by analyzing the 1000 mg/kg phthalate ester reference material and polypropylene spiked with brominated flame retardants (ERM-EC591). A hole puncher was used to punch out two discs at a time of the phthalate ester reference material, and a cutter was used to obtain pieces of the other materials. Each material was weighed in a sample cup for analysis. During the analysis of samples, phthalate esters and some of the regulated brominated flame retardants were quantitated using a one-point calibration curve. The remaining brominated flame retardants and specific regulated substances were quantitated using the correction factor database*2 that is included with Py-Screener Ver. 3.<h4>Conclusion</h4>Py-Screener Ver. 3 successfully determined in samples the concentrations of the regulated substances PIP (3:1), UV-328, DP, and SCCPs and MCCPs. Normally, SCCP and MCCP levels are tested using NCI, but Py-Screener Ver. 3 uses EI. This enables it to test for not only SCCPs and MCCPs but also phthalate esters, brominated flame retardants, and other regulated substances in just one analysis. In addition, by using the relative correction factors linked to DEHP in the phthalate ester reference material, the levels of these regulated substances were determined without the need for the corresponding reference materials. Py-Screener Ver. 3 can also create a screening program that addresses substance restrictions under the RoHS Directive, the US TSCA, and the POPs Convention.<h3>4. Thermo Fisher Scientific: Improving low carbon steel production in specialty steel processes</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/prima_pro_process_mass_spectrometer_an1626_7fc840235f.pdf">Full PDF for download</a></li></ul>World crude steel production reached 1,691 million tonnes in 2017, up by 5.3% compared to 2016.1 While much of this capacity is still produced in primary steel processes such as basic oxygen furnaces and electric arc furnaces, the need for refined steel with greater durability and resistance to heat and corrosion has led to the increased use of vacuum degassing processes, such as VOD and RH, in secondary steel production. These processes are able to achieve ultra-low levels of residual carbon, while at the same time retaining desired levels of other alloy materials. If these processes are to achieve the required level of steel product quality, they need fast, continuous gas analysis of the furnace exhaust gas. Without accurate information on the composition of the gas leaving the furnace, any variations in the decarburization process are only detected after the event, resulting in the production of out-of-specification steel.<h4>Advantages of mass spectrometry&nbsp;</h4>Traditional Non-Dispersive Infra-Red (NDIR) analyzers are used in many conventional steelmaking processes to measure CO and CO2 , but they can only sample at atmospheric pressure. In vacuum steelmaking the process pressure changes dramatically, typically from atmospheric pressure down to less than 1 mbar, over the 20-30 minutes of the melt. So NDIR analyzers have to sample some distance downstream from the process. Analytical data is updated several minutes after the gas leaves the melt and the control system is forced to operate on historic rather than real-time data.&nbsp;Paramagnetic analyzers can be used to measure O2 , while thermal conductivity analyzers can be used to measure H2 . These analyzers also suffer from slow response, while the need to operate three different types of analyzers adds to the plant maintenance burden. Moreover, the three analyzers cannot analyze inert gases, so N2 is calculated by difference, a result that suffers from the sum of the errors of the three analytical techniques.&nbsp;Mass spectrometry operates at high vacuum so it is ideal for monitoring vacuum processes. It is also able to monitor all seven components in Table 1 in seconds rather than minutes, ensuring the plant control model is frequently updated with accurate compositional data.<h4>Precision of analysis&nbsp;</h4>At the heart of the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=2&amp;search=Prima+PRO+Mass+Spectrometer">Thermo Scientific™ Prima PRO Mass Spectrometer</a> (MS) is a magnetic sector analyzer which offers unrivalled precision and accuracy compared with other mass spectrometers. Thermo Fisher Scientific manufactures both quadrupole and magnetic sector mass spectrometers; over thirty years of industrial experience have shown the magnetic sector based analyzer offers the best performance for industrial on-line gas analysis.&nbsp;Key advantages of magnetic sector analyzers include improved precision, accuracy, long intervals between calibrations, and resistance to contamination. Typically, analytical precision is between 2 and 10 times better than a quadrupole analyzer, depending on the gases analyzed and complexity of the mixture.&nbsp;A unique feature of the Prima PRO magnet is that it is laminated. Its analysis times are similar to a quadrupole analyzer, offering the unique combination of rapid analysis and high stability. This allows the rapid and extremely stable analysis of an unlimited number of user-defined gases. The scanning magnetic sector is controlled with 24-bit precision using a magnetic flux measuring device for extremely stable mass alignment.&nbsp;The ion source is an enclosed type for high sensitivity, minimum background interference, and maximum contamination resistance. This is a high-energy (1000 eV) analyzer that offers extremely rugged performance in the presence of gases and vapors that have the potential for contaminating the analyzer. Typical performance specifications for the Prima PRO MS are shown in Table 1. Analytical performance is demonstrated by analyzing the calibration bottle over 1 hour following calibration, with an analysis time of just 6 seconds. Standard deviations measured on the calibration cylinder will be equal to or better than the stated values.

News from LabRulezGCMS Library - Week 07, 2026

Although modern agriculture needs to be based on accurate real-time data on soil, plant, and environmental conditions, affordable, sufficiently sensitive, and robust monitoring devices for this purpose are currently missing. According to scientists, low-cost sensors based on new smart materials and printing technologies offer a suitable solution. The results of multidisciplinary research thus far and proposals for the development of these devices have been presented by researchers from Czechia, Great Britain, Spain, and the USA in a review article in the prestigious journal <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1">Nature Communications</a>.“Sensor technologies for monitoring plant health are still in their infancy. Only simple sensors capable of monitoring basic parameters such as pH, soil moisture, or temperature are commonly available on the market. However, if farmers are to face current challenges, including climate change, and ensure sufficient food for humanity, they need much more effective tools that will enable them to monitor, for example, various pathogens, including bacteria and fungi. In our opinion, a suitable solution is a combination of new smart materials and printing for the production of inexpensive, durable, and scalable materials,” said the article’s first author, David Panáček from CATRIN, who worked on the study during his internship at Imperial College London.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152">Sensors for monitoring plant health, for example, lag behind similar devices used in human medicine. According to the authors, advances in materials science, which will enable the development of scalable sensor technologies, play a key role in this potential shift. “Printing techniques, including inkjet printing, screen printing, aerosol printing, 3D printing, and direct laser writing, offer flexible ways to produce flexible sensors, large-area sensors, and sensors integrated directly into plants. The review article summarizes recent advances in printable low-dimensional materials for agricultural sensors, analyzes their physico-chemical properties in relation to sensor performance, and discusses key challenges and future opportunities requiring interdisciplinary integration,” said one of the corresponding authors, Michal Otyepka.The research brought together materials scientists, chemists, biologists, sensing experts, and printing technology specialists. Materials research and the use of graphene-based smart materials were led by scientists from CATRIN at Palacký University and VŠB-Technical University of Ostrava. Plant biologists from CATRIN contributed their knowledge of plant development, their responses to stress conditions, and the monitoring of their properties. Researchers from Imperial College London took care of the electronics, while representatives from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/36"> CEITEC – VUT</a> focused on printing technologies. The team also included leading experts in sensing from the Catalan Institute of Nanoscience and Nanotechnology in Barcelona, and Joseph Wang of the University of California San Diego, the “father of sensing and electrochemistry,” also contributed his extensive knowledge.“This is a groundbreaking study on this topic, which has managed to attract some truly big names in their respective fields. Last but not least, the study demonstrates that interdisciplinarity at CATRIN gives rise to completely new and promising research topics, such as plant sensing and its use for studying plant-environment interactions and smart agriculture,” added another corresponding author, Nuria De Diego.

Current sensors are not good enough. Scientists propose a new way to monitor plant health

Article

Application

Video

Presentation

Scientific article

Science and research

The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography Workshop

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

CATRIN

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

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Agilent Technologies

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We probably have all experienced this at some point when performing gas chromatography—our peak shape begins to appear a bit different.
In this webinar, we will discuss some of the most common chromatographic issues that you experience with gas chromatography and take a logical approach to finding the root cause and correcting the problem. Often the best way to approach troubleshooting is to also consider what cannot cause an issue so that precious time is not spent addressing something that is not relevant to the symptoms.
This webinar will arm you with simple tools, and a different way to look at troubleshooting, should a problem arise.
<blockquote>
Presenter: Alex Ucci (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.
</blockquote>

Agilent Technologies: Take the Trouble Out of Troubleshooting: Gas Chromatography

Take the Trouble Out of Troubleshooting: Gas Chromatography

The most common chromatographic issues that you experience with GC and take a logical approach to finding the root cause and correcting the problem.

Are you feeling the impact of Helium Shortage 4.0? We understand the difficulties and concerns you may be facing. From delays to longer turnaround time and rising costs, the GC analysis has indeed taken a direct hit from the fluctuating global helium levels.
To help users combat the issue, Shimadzu offers flexible solutions to ensure smooth operation while saving costs for GC analysis. In this webinar, learn how our GC instruments can effectively reduce helium consumption or switch easily to a different carrier gas for uninterrupted analysis. With Shimadzu, you can confidently navigate through the uncertain times brought on by Helium Shortage 4.0.
Join us and let&#39;s overcome this challenge together.
<h5>Learning Objectives:</h5>
<ul>
<li>How Shimadzu offers countermeasures to address the urgent issue of Helium Gas Supply Shortages</li>
<li>Learn about the capabilities of Shimadzu&#39;s GC instruments in reducing helium consumption for lower cost of analysis</li>
<li>Learn about the flexibility of Shimadzu&#39;s GC instruments to switch carrier gas easily to ensure uninterrupted analysis</li>
</ul>
<blockquote>
Presenter: Ryo Takechi (Global GC Product Manager, Shimadzu Corporation)
</blockquote>
<blockquote>
Ryo has a background in gas chromatography and engineering of analytical instrumentation over 10 years. He earned degrees in chemical engineering from Doshisha University in Kyoto, Japan.
</blockquote>
<blockquote>
Q&amp;A Respondent: Dr. Jackie (Assistant Product Manager (GC &amp; GCMS), Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
Dr. Jackie obtained his PhD in Analytical Chemistry from the National University of Singapore. He has garnered over 9 years of research, training, and facilitation experience. Jackie meets scientists from various industries to share technical knowledge and collect feedback, understanding their problems and helping them find well-suited solutions in GC-related analyses.
</blockquote>

Shimadzu: Beat the Helium Shortage, Time to Think Hydrogen!

Beat the Helium Shortage, Time to Think Hydrogen!

Learn how our GC instruments can effectively reduce helium consumption or switch easily to a different carrier gas for uninterrupted analysis.

Digital transformation is a journey driven by the desire to fundamentally improve laboratory working practices by leveraging the latest advances in technology. Whether it be a need to eliminate errors, operate more efficiently, or reach confident results faster, laboratories are focusing more than ever on software.
Designed as a scalable solution for modern, dynamic (often cloud-based) environments, the Thermo Scientific™ Ardia™ Platform brings together chromatography and mass spectrometry, connecting data and instruments, helping scientists get closer to the truth. In this webinar, discover how you can reap the benefits of a connected platform to maximize instrument utilization, streamline lab and data management, and realize true efficiency gains.
Key learning objectives
<ul>
<li>Discover how you can enable wider collaboration within your business</li>
<li>Learn how you can access, monitor and schedule instruments from a single location</li>
<li>Find out how you simplify data storage and expedite review</li>
</ul>
Who should attend?
<ul>
<li>Lab managers</li>
<li>Principle scientists</li>
<li>Technical specialists</li>
<li>MS users</li>
<li>IT managers</li>
</ul>
<blockquote>
Presenter: Peter Zipfell (Product Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
For the past 22 years, Peter Zipfell has worked extensively with chromatography hardware and software transitioning from LC-MS method development through HPLC technical support to chromatography data systems. He joined Thermo Fisher Scientific over 13 years ago and more recently became involved as the lead for Ardia platform product marketing. His focus has always been to support Thermo Fisher customers by delivering software solutions across multiple industries to enable them to improve their current workflows and increase productivity.
</blockquote>
<blockquote>
Presenter: Kevin Schauer (Product Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Kevin Schauer is a molecular biologist by training and has been working with chromatography and mass spectrometry instrumentation for over 10 years. He joined Thermo Fisher Scientific five years ago as a field applications scientist where he worked with customers to better leverage the capabilities of the mass spectrometry instrumentation for their life science research. He transitioned to the Ardia platform product management team several years ago where he now works to produce software that allows users to operate more efficiently and get their work done faster.
</blockquote>
<blockquote>
Presenter: Georgina Wynne Hughes (Editorial Team, SelectScience)
</blockquote>
<blockquote>
Georgina studied at Birmingham University where she gained a BSc in Biomedical Science, and an MSc by Research in Cancer and Genomic Sciences, which focused on defective autophagy in rare neurodegenerative diseases. As a member of the Editorial team, she now plays an integral role in shaping the content on SelectScience.
</blockquote>

SelectScience: Take control of your data and instruments: Your journey starts here

Take control of your data and instruments: Your journey starts here

The Thermo Scientific Ardia Platform brings together chromatography and mass spectrometry, connecting data and instruments.

Take control of your data and instruments: Your journey

<h5>Join us Wednesday, June 21, for this information-packed, 30-minute webinar to learn</h5>
<ul>
<li>Fundamentals of Purge and Trap: what it is and how it works</li>
<li>Requirements of a trap and how they adsorb and release volatile compounds</li>
<li>Purge gas selection</li>
<li>The effects of purge parameters on purge efficiency</li>
</ul>
This is a must-attend session if:
<ul>
<li>You work with purge and trap methods in the soil, wastewater and/or drinking water fields</li>
<li>Are a scientist or analyst wishing to learn more about P&amp;T analysis </li>
<li>Are an environmental scientist/technician, analytical chemist or lab manager</li>
</ul>
<blockquote>
Presenter: Amy Nutter (the VOC technical product specialist at Teledyne Tekmar)
</blockquote>
<blockquote>
Amy currently is focused on OEM and customer technical training and application support on the Purge and Trap product line. Previously, Amy worked for the City of Cincinnati in both the drinking water and wastewater laboratories.
</blockquote>
To attend, please select the time on Wednesday, June 21, that works best for you. We look forward to sharing this valuable information.

Teledyne Tekmar: Fundamentals of Purge & Trap

Fundamentals of Purge & Trap

Fundamentals of Purge and Trap. Requirements of a trap. Purge gas selection. The effects of purge parameters on purge efficiency...

Webinars will cover the following Gas Chromatography topics:
<ul>
<li>6/27 - Vaporizers for LPG Samples</li>
<li>7/11 - Dynamic Blending for Linearity and LDL</li>
<li>7/18 - GC Valves: Purposes and Service</li>
<li>7/25 - Calibration Techniques for Accurate Data</li>
<li>8/1 - Sample Capture, Transport, and Introduction</li>
<li>8/8 - GC Detectors I: PDHID and SCD</li>
<li>8/15 - GC Autosamplers for Gas and LPG Samples</li>
<li>8/22 - GC Detectors II: The Strengths of Mass Spectrometry</li>
<li>8/29 - Methanizers for Trace CO &amp; CO2</li>
<li>9/5 - Training Program for GC Operators</li>
</ul>
<blockquote>
Presenter: John Wasson (President, Wasson-ECE Instrumentation, Inc.)
</blockquote>
<blockquote>
John Wasson has over 40 years of experience in Gas Chromatography and Chemical Instrumentation.
</blockquote>

Wasson-ECE Instrumentation: Free GC Webinar Series

Vaporizers for LPG Samples

Verification of Incoming Raw Materials in Paper Bags, Sacks, Tubs, Bottles, and Barrels Without a Clean Room or Opening the Container using SORS Raman Technology.
<blockquote>
Presenter: Luciana Terra (Application Scientist, Molecular Spectroscopy, Agilent Technologies, Inc.)
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<blockquote>
Luciana Terra has a Bachelor’s degree in Industrial Chemistry from the Federal University of Alfenas (Unifal-MG) as well as a Ph.D. in Analytical Chemistry, on Chemometrics, from the State University of Campinas (Unicamp), where she developed work focused on petroleum quality and derivatives using high-resolution Mass Spectrometry, NIR, and chemometrics methodologies. As part of her Ph.D., she also worked at the University of Calgary in Canada. While completing her Master’s Degree at Unicamp, Luciana developed a new methodology for drug polymorphism detection using NIR imaging and chemometrics tools for quality assurance in the pharmaceutical industry. In 2019, she joined Agilent Technologies as an Application Scientist for Molecular Spectroscopy in UV-Vis, Fluorescence, IR, and Raman techniques, at Agilent Technologies, in Brazil.
</blockquote>

Agilent Technologies: Identification of Incoming Raw Materials in Paper Bags, Sacks, Tubs, Bottles, and Barrels

Identification of Incoming Raw Materials in Paper Bags, Sacks, Tubs, Bottles, and Barrels

Verification of Incoming Raw Materials in Paper Bags, Sacks, Tubs, Bottles, and Barrels using SORS Raman Technology.

Identification of Materials in Bags, Sacks, Tubs, Bottles...

This meeting covers the latest trends and techniques to meet current water and environmental testing demands for emerging contaminants and evolving regulations. Our guest speakers from the water industry and environmental research and testing laboratories will share their expertise on their latest work, analytical workflows, and automation.
Join us and discover valuable insights to maximise testing productivity and instrument uptime, simplify workflows and standardise data workup.
<h3>June 27 (Day 1) Emerging contaminants</h3>
This session will explore PFAS, microplastics, untargeted screening, automation and sample preparation.
Attend the whole day or selected presentations only.
<h5>10:00 Online access opens (Streaming begins 09:30 BST/10:30 CEST)</h5>
<h5>10:30 Opening of the event, welcome and introduction</h5>
<ul>
<li>Presenter: Jeff Stubbs (Thermo Fisher Scientific)</li>
</ul>
<h5>10:50 Screening of unknowns using Thermo Scientific Orbitrap MS and Thermo Scientific Compound Discoverer software</h5>
<ul>
<li>Presenter: Janine Elliot (Scottish Environment Protection Agency)</li>
</ul>
<h5>11:20 Biotoxins, seafood safety and mass spectrometry</h5>
<ul>
<li>Presenter: Ben Maskrey (Centre of Environment, Fisheries and Aquaculture Science)</li>
</ul>
<h5>11:50 Determination of microplastics with pyrolysis and GC-MS</h5>
<ul>
<li>Presenter: Dr. Michael Soll (Frontier Lab Europe)</li>
</ul>
<h5>12:20 Break</h5>
<h5>12:40 What combustion ion chromatography sum parameter analysis can do for the analysis of PFAS</h5>
<ul>
<li>Presenter: Dr. Lewis Mark (A1-envirosciences Limited)</li>
</ul>
<h5>13:10 Use of Thermo Scientific Exploris 120 Orbitrap HRAM-LC-MS for the analysis of 47 PFAS compounds in UK waters</h5>
<ul>
<li>Presenter: John Quick (ALS Environmental Ltd.)</li>
</ul>
<h5>13:40 Workshop - new untargeted PFAS analysis workflow capabilities within Compound Discoverer software</h5>
<ul>
<li>Presenter: Frans Schoutsen (Thermo Fisher Scientific)</li>
</ul>
<h5>14:10 Break</h5>
<h5>15:10 Starting your voyage into PFAS? Tools and protocols to succeed</h5>
<ul>
<li>Presenter: Ed George (Thermo Fisher Scientific)</li>
</ul>
<h5>16:10 Workshop - new approaches in performing automation by GC (and LC)</h5>
<ul>
<li>Presenter: Dan Carrier (Thermo Fisher Scientific)</li>
</ul>
<h5>16:30 Closing of the live streaming event</h5>

Thermo Scientific: Water & Environmental Analysis User Meeting - Day 1

Water & Environmental Analysis User Meeting - Day 1

Streaming live from our Demo Centre in Hemel Hempstead | Join the complete event or the presentations of your choice only.

How about a 20 minute coffee break along with a bite of Empower? Here you go!
What you can learn: 
<ul>
<li>What&#39;s the difference between Archive and Backup and why do you need both</li>
<li>The cheapest, the fastest, or the most definitive data management strategy is meaningless if the data is untrustworthy</li>
<li>How including a complementary archive strategy to your existing backup will not only improve efficiency, but can reduce costs and regulatory risk</li>
<li>How both approaches are viable and the business value each one can offer</li>
</ul>
Register and prepare a coffee!
<blockquote>
Presenter: Ralf Schröder (Informatics Product Marketing Europe·Waters GesmbH)
</blockquote>

Waters Corporation: Waters Informatics series #5: Archive vs Backup (Po2)

Waters Informatics series #5: Archive vs Backup (Po2)

What's the difference between Archive and Backup and why do you need both?

There are a variety of sample preparation methods used for the analysis of drugs of abuse in physiological sample matrices such as blood, urine, oral fluid.
These include simple ‘dilute and shoot’, protein removal, phospholipid removal, liquid -liquid and solid phase extraction as well as many others.
With each method there is variability in the number of steps involved, specificity, and the suitability to automation.
Choosing the most suitable sample preparation technique can depend on the type of analytical challenge being addressed, for example certain methods can be used to screen for a large number of compounds and others can be selected to enhance sensitivity for a particular compound or class of compounds. 
In this session, a number of sample preparation methods will be discussed in terms of their strengths and limitations and suitability for particular forensic toxicology applications.
This webinar will prepare the audience for the third session in the Forensic Toxicology Summer Webinar series where the use of a simple generic protocol is used to analyse a wide range of drugs of abuse in whole blood to support driving under the influence of drugs investigations.
Learning objectives:
<ul>
<li>Uncover an overview of selective and generic methods for biological fluids</li>
<li>How these sample preparation techniques can be applied to your most complex toxicological samples</li>
</ul>
<blockquote>
Presenter: Jonathan Danaceau, Ph.D. (Principal Scientist, Waters Corporation)
</blockquote>
<blockquote>
Dr. Jonathan Danaceau, Ph.D. is a Principal Scientist with Waters. He received his B.S. in Biology from Allegheny College and a Ph.D. in Neuroscience from the University of Utah (Salt Lake City, UT). Jon came to Waters in 2011 after spending several years in the forensic toxicology and sports doping fields. Since joining Waters, he has focused on sample preparation and LC/MS/MS solutions for forensic, clinical research, and other bioanalytical applications. He is an expert in sample preparation and bioanalytical method development and has published several papers in these fields. Jon is currently with the Sample Preparation and Automation group within the Consumables and Lab Automation division at Waters.
</blockquote>

Waters Corporation: Sample Preparation Strategies for Forensic Toxicology Testing

Sample Preparation Strategies for Forensic Toxicology Testing

A number of sample prep methods will be discussed in terms of their strengths and limitations and suitability for particular forensic toxicology apps..

Sample Preparation Strategies for Forensic Toxicology

Microplastics are a rapidly emerging concern that produce a variety of challenges proven harmful to environment, human and animal health.
In this webinar, a solution for characterizing and quantifying microplastics using the micro-furnace Pyrolysis-GC/MS will be discussed.
 We will host a Q&amp;A session after the presentation to address any questions or comments.
<blockquote>
Presenter: Alan Owens (GCMS Product Manager, Shimadzu Scientific Instruments)
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<blockquote>
Alan Owens is the GCMS Product Manager at Shimadzu Scientific Instruments. Alan received his B.S. degree in Biology and Chemistry from Hampden-Sydney college. He then joined Shimadzu as a GCMS Product Specialist at the corporate headquarters in Columbia, MD. Before his time with Shimadzu, he comes from a flavor and fragrance background with expertise in advanced sample introduction techniques such as SPME and Dynamic headspace. He has since expanded into all sample introduction techniques specifically tailored towards Pyrolysis with a heavy influence of plastics and polymers.
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<blockquote>
Presenter: Rojin Belganeh (Technical &amp; Marketing Director, Frontier Laboratories-North America)
</blockquote>
<blockquote>
Rojin Belganeh is the Technical &amp; Marketing Director at Frontier Laboratories-North America. Rojin graduated from the University of Houston with a Bachelor of Science in Chemistry. She started her profession as an analytical chemist in oil &amp; gas industry in 2012. As an analytical chemist, Rojin worked with various analytical instruments, such as Pyrolysis GCMS, TGA, FTIR, and X-Rays for material characterization, polymer identification, and contamination analysis. She also holds an MBA degree concentrating in strategic marketing from the University of Houston-Victoria. As a former user for more than five years, Rojin joined Frontier Laboratories in May of 2017. She is very passionate in creating awareness about Frontier technology and providing technical support to users.
</blockquote>
<blockquote>
Presenter: Athena Nguyen (Technical Support Scientist, Frontier Laboratories-North America)
</blockquote>
<blockquote>
Athena Nguyen is a Technical Support Specialist at Frontier Labs Americas. She graduated from the University of Houston with a bachelor’s degree in science in chemistry in 2014. The first three years after graduating, Athena worked as an analytical chemist. She has experience using multiple analytical instruments, including GC/MS/FID/ECD, with applications in the oil and gas industry. Athena joined Frontier Lab in 2020 and provides technical and product support to Frontier’s users.
</blockquote>
<blockquote>
Presenter: Andy Sandy (GCMS Application Scientist, Shimadzu Scientific Instruments)
</blockquote>
<blockquote>
Andy Sandy is a Gas chromatography-Mass Spectrometry (GC-MS) Applications Scientist at Shimadzu Scientific Instruments, USA. In 2016, he joined the company. At Shimadzu he is a part of a dynamic application group, which is responsible for developing applications that provide solutions to complex analytical issues. Prior to working at Shimadzu, he completed a post-doctoral study at University of Illinois at Chicago, where he focused on developing environmental analytical methods for identifying and measuring emerging contaminant in the environment.
</blockquote>

Shimadzu: A Simple, Effective Solution for Microplastics Characterization and Quantitation using Pyrolysis GC-MS

A Simple, Effective Solution for Microplastics Characterization and Quantitation using Pyrolysis GC-MS

In this webinar, a solution for characterizing and quantifying microplastics using the micro-furnace Pyrolysis-GC/MS will be discussed.