Evaporation is a fundamental process in chemistry and laboratory settings, essential for concentrating solutions, purifying compounds, and drying samples. While traditional evaporation relies on heat to remove solvents, evaporation under vacuum offers a more efficient and versatile approach. By reducing the pressure, vacuum evaporation lowers the boiling point of solvents, allowing for faster and safer evaporation at lower temperatures. This article explores when and why evaporation under vacuum is helpful, highlighting its advantages, applications, and key considerations.<h3>Understanding Evaporation Under Vacuum</h3>Evaporation under vacuum, also known as vacuum evaporation, involves reducing the atmospheric pressure around a liquid, which decreases its boiling point. This allows the solvent to evaporate at a lower temperature than it would under normal atmospheric conditions. The process typically employs equipment like rotary evaporators and vacuum ovens, which create a controlled low-pressure environment to facilitate efficient solvent removal.<h4>How It Works:</h4><ul><li>Pressure Reduction:&nbsp;A vacuum pump reduces the pressure in the system.&nbsp;</li><li>Lower Boiling Point:&nbsp;The reduced pressure lowers the boiling point of the solvent.&nbsp;</li><li>Evaporation:&nbsp;The solvent evaporates at the lower temperature, leaving behind the concentrated sample or dried product.</li></ul><h3>Advantages of Vacuum Evaporation&nbsp;&nbsp;</h3><h4>Enhanced Efficiency and Speed&nbsp;</h4>Vacuum evaporation significantly speeds up the solvent removal process. The lower boiling point means that solvents evaporate more quickly, reducing the time required for concentration or drying.<h4>Lower Temperatures</h4>Evaporating at lower temperatures is crucial for preserving thermally sensitive compounds that might degrade under higher heat. This is particularly important in pharmaceutical and biochemical applications.<h4>Improved Safety&nbsp;</h4>By avoiding high temperatures, vacuum evaporation reduces the risk of thermal decomposition and hazardous reactions. It also minimizes the potential for solvent vapors to become flammable or explosive.<h4>Reduced Solvent Usage and Waste&nbsp;</h4>Vacuum evaporation often requires less solvent and generates less waste. This is beneficial for both cost savings and environmental sustainability. For example, Organomation <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=338&amp;distributorItems=332&amp;search=evap">large scale evaporators</a> are capable of recollecting up to 97% of starting solvent.<h3>Applications in Laboratory Settings&nbsp;</h3><h4>Sample Concentration&nbsp;</h4>Vacuum evaporation is widely used to concentrate samples for analytical techniques such as <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/hplc-sample-preparation">high-performance liquid chromatography</a> (HPLC) and <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-gc-ms/ms-analysis">gas chromatography-mass spectrometry</a> (GC-MS). Concentrating the sample improves the detection limits and accuracy of these methods.<h4>Drying Samples</h4>It is also employed for drying samples before further analysis or storage. Removing moisture is crucial for accurate weight measurements and preventing degradation of sensitive compounds.<h4>Preparation for Crystallization&nbsp;</h4>In crystallization studies, vacuum evaporation can be used to concentrate solutions to supersaturation, facilitating the formation of crystals.<h3>Industrial Applications of Vacuum Evaporation&nbsp;</h3><h4>Environmental Analysis&nbsp;</h4>In environmental labs, vacuum evaporation concentrates pollutants from large volume water samples, allowing for more accurate detection and quantification of contaminants<h4>Chemical Manufacturing&nbsp;</h4>Vacuum evaporation is employed in chemical manufacturing for solvent recovery and recycling, reducing costs and environmental impact.<h4>Pharmaceutical Industry&nbsp;</h4>In pharmaceutical manufacturing, vacuum evaporation is essential for purifying active pharmaceutical ingredients (APIs) by removing solvents and other impurities without degrading the product.<h4>Food and Beverage Industry&nbsp;</h4>The food industry uses vacuum evaporation to concentrate flavors and extracts. This process enhances the intensity of flavors while preserving the quality of the ingredients.<h3>Key Considerations for Vacuum Evaporation&nbsp;</h3><h4>Equipment Selection</h4>Choosing the right equipment is crucial for successful vacuum evaporation. The selection depends on the sample type, volume, and specific application requirements. Here are the main types of evaporators that integrate vacuum:Rotary evaporators: Rotary evaporators, commonly referred to as "rotovaps," are widely used in laboratories for efficiently removing solvents from samples. They consist of a rotating flask, a condenser, and a vacuum system. The rotating motion increases the surface area for evaporation, and the vacuum reduces the boiling point of the solvent, making the process faster and more efficient.Large Scale Parallel Evaporators: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=338&amp;distributorItems=332&amp;search=evap">Organomation S-EVAP</a> is a specialized evaporator designed for the efficient concentration of multiple samples simultaneously. The optional vacuum manifold system to reduce the boiling point of solvents, facilitating faster evaporation at lower temperatures. This system is ideal for laboratories needing to concentrate samples in Kuderna-Danish (KD) flasks, often used in environmental testing, food and beverage analysis, and pharmaceutical research. The S-EVAP provides precise control over temperature and vacuum levels, ensuring reproducibility and safety in sample processing.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_S_EVAP_RB_Solvent_Evaporator_10_position_48376ce49a.jpg" alt="Organomation: When is Evaporation Under Vacuum Helpful?: Organomation S-EVAP-RB Solvent Evaporator - 10 position." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_S_EVAP_RB_Solvent_Evaporator_10_position_48376ce49a.jpg 120w," sizes="100vw" width="430" height="560">Vacuum ovens: Vacuum ovens are used for drying samples that are sensitive to heat or require low-temperature evaporation. They provide a controlled environment where the pressure and temperature can be precisely adjusted. Vacuum ovens are ideal for drying solid and viscous samples, as well as for performing vacuum distillations.Centrifugal evaporators: Centrifugal evaporators use a combination of vacuum, heat, and centrifugal force to evaporate solvents. They are particularly useful for high-throughput applications where multiple samples need to be processed simultaneously. These systems are commonly used in drug discovery and biochemical research.<blockquote>Discover: <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/when-nitrogen-blowdown-is-preferable-over-centrifugal-evaporation">When Nitrogen Blowdown is Preferable Over Centrifugal Evaporation</a></blockquote>Falling film evaporators: Falling film evaporators are used for continuous evaporation processes, where the liquid flows down a heated surface in a thin film. The vacuum system reduces the boiling point, and the thin film facilitates rapid solvent evaporation. These evaporators are used in large-scale industrial applications, such as in the food and beverage industry.Freeze dryers: Freeze dryers, or lyophilizers, integrate vacuum to sublimate frozen solvents directly from the solid to the gas phase. This technique is used for drying thermally sensitive materials, such as biological samples and pharmaceuticals, without damaging their structure or activity.<blockquote>Discover: <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/how-does-nitrogen-blow-down-compare-to-lyophilization">How Nitrogen Blow Down Compares to Lyophilization</a></blockquote>Spray dryers: Spray dryers use a vacuum system in combination with a spray mechanism to evaporate solvents from liquid samples. The liquid is atomized into fine droplets, which are then exposed to a heated gas stream under vacuum, causing rapid solvent evaporation. This method is used for producing powders and granules from liquid solutions.<h4>Solvent Properties</h4>Understanding the properties of the solvents being used is essential. Different solvents behave differently under vacuum, and their boiling points, vapor pressures, and potential for forming azeotropes must be considered.Vacuum evaporators excel in processing samples with naturally high boiling points, such as dimethyl sulfoxide (DMSO), N,N-dimethylformamide (DMF), and water. The reduced pressure lowers the boiling points, making the evaporation process more efficient and less thermally stressful for sensitive samples.Understanding how solvents behave under reduced pressure, including potential azeotrope formation, is critical for effective evaporation.<h4>Process Control&nbsp;</h4>Monitoring and controlling temperature and pressure are vital for optimizing the evaporation process. Precise control ensures efficient solvent removal while protecting the sample from degradation.<h4>Safety Precautions</h4>Proper handling of volatile and hazardous solvents is necessary to prevent accidents. This includes using appropriate containment, ventilation, and personal protective equipment.Evaporation under vacuum is a powerful and versatile technique with numerous advantages over traditional evaporation methods. It offers enhanced efficiency, lower operating temperatures, and improved safety, making it invaluable in both laboratory and industrial settings. As technology advances and new applications arise, the role of vacuum evaporation will continue to expand, driving innovation and improving outcomes across various scientific and industrial fields.<blockquote>To find out the best evaporation method for your needs, start a conversation with our experts at <a href="mailto:sales@organomation.com">sales@organomation.com</a>, or use our handy <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/evaporation-method-recommendation-tool">evaporation method recommendation tool</a>.</blockquote>

When is Evaporation Under Vacuum Helpful?

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 12th May 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you technical note by Agilent Technologies, application note by Shimadzu and poster by MDCW!<h3>1. Agilent Technologies: How Does Bleed Impact GC/MS Data and How Can It Be Controlled?</h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/te_bleed_impact_gc_ms_data_5994_7586en_agilent_1_728100a153.pdf">Full PDF for download</a></li></ul><h4>Understanding column bleed&nbsp;</h4>Column bleed remains one of the most commonly observed yet misunderstood aspects of mass spectrometry (MS) data. Bleed elevates chromatographic baselines and creates spectral interference, lowering the quality of and confidence in your data. To understand bleed, it must first be considered where the bleed originates. While columns come in a wide variety of phase types, the most commonly used columns today, such as the 1, 5, and 624, are categorized as wall-coated open tubular (WCOT) columns. These columns are composed of fused silica tubing (with varying internal diameters, measured in mm), internally coated with a thin film of stationary phase (with varying thicknesses, measured in μm), as shown in Figure 1. This coated stationary phase interacts with analytes and creates the selectivity and retention characteristics of the chromatography; but, these same characteristics are the origins of column bleed.Column phases can be made from a wide variety of polarities of liquid polymers with a polysiloxane backbone. When heat is applied, the terminal end of the stationary phase polymer starts to bend back and attack itself, which is called "backbiting." Ring structures, which are thermodynamically stable, become liberated and increase the noise and raise the baseline, as shown in Figure 2. The process is then repeated. The higher the temperature provided, the faster the reaction is driven, which is why there is an increase in baseline at temperatures above 300 °C.&nbsp;An increase in the rise of a baseline can be problematic for low signal-to-noise analytes, as peak integration can negatively impact data quality. Stable, flat baselines optimize the accuracy and repeatability of peak integration. When working with sensitive detectors, such as MS, an increase in the sensitivity of the detector also increases the background noise and bleed detection, causing excess column bleed to be detrimental to the sensitivity of trace level compounds.<h4>Experimental</h4>An Agilent<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=+8890+GC"> 8890 GC</a> coupled with a flame ionization detector (FID), and an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=5977B+GC%2FMSD+">5977 Series B GC/MSD </a>were used to collect data. Data acquisition was performed using Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=OpenLab+ChemStation">OpenLab ChemStation</a> and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=MassHunter+acquisition+software">MassHunter acquisition software</a>. Additionally, an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=Intuvo+9000+GC">Intuvo 9000 GC</a> coupled with an FID was used to collect data. <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=J%26W+DB-5Q">J&amp;W DB-5Q and J&amp;W&nbsp;HP‑5Q GC columns </a>were compared to various conventional, commercially available 5ms GC columns.<h4>Results and discussion&nbsp;</h4><h5>Comparisons of bleed profiles at upper temperature&nbsp;limits&nbsp;</h5>To compare the thermal stability of the HP-5Q columns to conventional 5ms columns, columns were installed on an 8890 GC equipped with dual split/splitless inlets and dual FIDs, and experiments were done in tandem. After confirming that column connections were properly installed, free of leaks, and conditioned, the oven temperature was ramped up to temperatures of 330 and 340&nbsp;°C and held for 10 minutes each. Then, the oven temperature was ramped to a final temperature of 350&nbsp;°C (the programed MAOT of the column phases) and held for 30 minutes. As shown in Figure&nbsp;4, both the DB-5Q and HP-5Q maintained ultralow FID response at the upper temperature limits, both maintaining column bleed levels below 1.0 pA at 340 °C. Also, when operating the columns at 350 °C (the programmed maximum temperature) over a period of 10 hours, both the DB-5Q and HP-5Q maintained bleed levels below 2.0 pA, while the conventional 5ms columns X and Y had bleed levels at 10 and 4 pA respectively, demonstrating the increased thermal stability of the DB-5Q and HP-5Q GC columns.<h4>Conclusion&nbsp;</h4>While column bleed is a normal phenomenon, there are ways to decrease its impact on the analysis and sensitivity of the detector being used. Improved column technology, with the introduction of the Agilent J&amp;W DB-5Q and HP-5Q GC columns, has provided an increase in thermal stability that dramatically reduces column bleed. The decrease in column bleed at high temperatures allows an increase in sensitivity of mass spectrometers, as the spectral interference from ions due to backbiting of column phase is reduced. This demonstrates that the DB-5Q and HP-5Q GC columns are optimal for use with sensitive detectors such as GC/MS, triple quadrupole GC/MS, and GC/Q-TOF.<h3>2. MDCW: Group-type quantitation of hydrocarbons in aviation fuel using GC×GC–FID&nbsp;</h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/2025_001_MDCW_ASTM_D8396_9a3aa6f3e5.pdf">Full PDF for download</a></li></ul>Accurate hydrocarbon composition of finished fuels, such as aviation fuel, is required to ensure quality control and to determine the effects of processes in fuel production. This has become even more important with the development of novel renewable fuels, such as sustainable aviation fuels (SAFs).Here, we demonstrate the use of reverse fill/flush (RFF) flow-modulated GC×GC–FID and automated group-type data processing to provide fast and accurate quantitative information on hydrocarbon composition.<h4>Experimental</h4><ul><li>Samples: A reference standard and reference blends of both diesel and aviation turbine fuel.&nbsp;</li><li>GC×GC: Modulator: INSIGHT®-Flow reverse fill/flush (RFF) flow modulator (SepSolve Analytical); Modulation period (PM): 7.8 s. Carrier gas: H2.&nbsp;</li><li>Column set: ASTM D8396 reverse phase column set (SepSolve Analytical, PN: OEM-SEP-COLKIT-10)&nbsp;</li><li>FID: Total H2 flow (column &amp; fuel): 50 mL/min; Air flow: 350 mL/min: Makeup gas flow: 5 mL/min; Temperature: 300 °C.&nbsp;</li><li>Software: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?search=ChromSpace%C2%AE+GC%C3%97GC+software">ChromSpace® GC×GC software</a> for instrument control and data processing</li></ul><h4>Results and discussion</h4><h5>Optimising the GC×GC separation&nbsp;</h5>Separation was optimised using a custom column set and larger loop volume, enabling excellent separation of the key chemical classes (Figure 2).The INSIGHT-Flow modulator used in this study has an adjustable sample loop (in the range of 25-250 μL) for greater flexibility in method development. The reference standard was analysed in replicate (n=10) to assess method repeatability and precision. The relative standard deviation (RSD) of the raw peak areas were all &lt;2%, while the calculated mass percent values were consistently within 0.5% of the known composition.&nbsp;<h5>Group-type classifications&nbsp;</h5>Group-type analysis of these key chemical classes was then performed on various fuels using the ‘stencil’ workflow in ChromSpace software (Figure 3). Once a stencil is created, it can be saved and applied to multiple data files in an automated batch sequence to generate area percent reports. This means that the method is then scalable across multiple GC×GC–FID platforms for fast classification. This proven workflow has already gained accredited status in a number of high-throughput environmental labs for the analysis of total petroleum hydrocarbons (TPH).<h4>Conclusions</h4>This poster has shown an end-to-end workflow for ASTM Method D8396, specifically:&nbsp;<ul><li>Proven reverse fill/flush modulation using the INSIGHT-Flow, a modulator in operation in numerous high-throughput labs across the world.&nbsp;</li><li>Optimal class separation with a tried-and-tested column set.&nbsp;</li><li>Fast, straightforward group-type data processing with ChromSpace software.&nbsp;</li><li>Doubled productivity with optional dual-channel GC×GC technology.&nbsp;</li><li>A retrofittable solution for all popular GCs, allowing existing systems to be upgraded to GC×GC capability</li></ul><h3>3. Shimadzu: Analysis of Dechlorane Plus Residues in Environmental Water Using <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ8050+NX">GCMS-TQ8050 NX</a> with Boosted Efficiency Ion Source(BEIS) and Long-Life Filament</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_03_gcmsms_566_en_93e41bdffc.pdf">Full PDF for download</a></li></ul>User Benefits:<ul><li>The combination of the BEIS and long-life filament enables high sensitivity analysis while maintaining long-term stability.</li><li>The 13C-Dechlorane 602 is used as internal standard(IS) in the optimization method to avoid the interference of isotope IS with target components in MRM mode.</li></ul>Dechlorane Plus (DP) is a synthetic substance mainly used as an adhesive, sealant and flame retardant for polymers in the industrial field. Due to its strong persistence and bioaccumulation, there is a significant risk to human and environmental health. In 2018, the European Chemicals Agency (ECHA) identified it as a Substance of Very High Concern (SVHC), and in June 2021 proposed to add it to Appendix XVII of the REACH regulation to restrict it, proposing to ban the production and use of DPs and prohibit the production and launch on the market of goods with DP content equal to or greater than 0.1% (by weight). In May 2023, the Stockholm Convention on Persistent Organic Pollutants (POPs) listed DP in Appendix A. At the same time, DP is also included in China's List of new pollutants under Key Control (2023 version).&nbsp;A method for the determination of residues of DPs in environmental water was established by using the Shimadzu <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ8050+NX">GCMS-TQ8050 NX</a> equipped with Boost Efficiency Ion Source and long-life filament. This application news provides an important analytical method for determine the residue levels of new pollutantsin environment with high sensitivity and good stability.<h4>Quantitative Analysis</h4>In the initial scheme, 13C-DP was used as the IS. However, due to the same retention time of 13C-DP and the target compound, the characteristic ions cause interference, resulting in a large calibration curve intercept and a high RF RSD (&gt;80%). Therefore, 13C-Dechlorane 602 is used as the IS instead. Its retention time differsfrom target DP, which helps avoid the interference.<h4>Evaluation of Durability in Analysis of Standard Solution and Samples</h4>The sample solution and 0.5 ng/mL standard solution were tested to evaluate the long-term durability of response. A total of 500 analyses of the sample and 80 analyses of standard solution were conducted. Fig.3 shows the durability test results of the standard solution. The horizontal axis shows the number of analyses, while the vertical axis shows the peak area ratio for each analysis number. The results indicate that the changes in peak area ratio and ion proportion were within ±20% of the average value (calculated from very beginning 20 injections).<h4>Conclusion</h4>A method for the determination of DP residues in environmental water was established by using the Shimadzu GCMS-TQ8050 NX combined with BEIS and long-life filament. The target compound exhibited good linearity in the concentration range of 0.2 to 50.0 ng/mL and the RF RSD of calibration curve was less than 15 %. The standard solution of 0.2 ng/mL was injected for 10 consecutive times to measure the LOD with results of 0.063 and 0.103 ng/mL. The durability of DP response was investigated by alternating test of sample solution and standard solution, and the peak area ratio in standard solution fluctuated within 20% in 500 injection of samples. The recovery rate of 1 ng/mL in blank samples was around 102 %. The method has high sensitivity and good repeatability and is suitable for the determination of DP residues in surface water, groundwater, industrial wastewater, and domestic sewage.

News from LabRulezGCMS Library - Week 20, 2025

The study aimed to develop a reliable GC–MS/MS method for multiresidue pesticide analysis in mealworm (Tenebrio molitor) larvae, which are known for their complex composition and high lipid content. The standard QuEChERS-based method was unsuitable for this matrix, so the authors optimized the extraction protocol by using 0.1% formic acid in acetonitrile and PSA-based cleanup to minimize matrix effects and improve analyte recovery.The final method enabled the detection and quantitation of 247 pesticides with high accuracy and low detection limits. Its application to field samples revealed triadimenol uptake from feed, indicating the method's practical utility. This approach provides a valuable tool for pesticide monitoring in edible insects for regulatory and industry purposes.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330">GC–MS/MS–based multiresidue pesticide analysis in mealworm (Tenebrio molitor) larvae: Optimization of standard QuEChERS-based method to minimize matrix effects</a></h4>Hyun Ho Noh, Chang Jo Kim, So-Hee Kim, Hye-Ran Eun, Yongho Shin, Won Tae Jeong&nbsp;Food Chemistry: X, Volume 27, April 2025, 102386<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.fochx.2025.102386">https://doi.org/10.1016/j.fochx.2025.102386</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.The consumption of animal products has increased with the increasing global population, and the demand for consumable crop–derived calories and proteins is expected to increase 2.1-fold by 2050 (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0050">Hunter et al., 2017</a>). Given the need to promote sustainable food production, considerable attention has been drawn to decreasing the reliance of pest management on chemicals (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0110">Rockstrom et al., 2017</a>). However, the fact that wheat, corn, and cotton losses due to pests reached 38.3&nbsp;% in 1964–2003 (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0085">Poppe et al., 2003</a>) indicates the importance of pesticides for preventing crop damage by fungi, insects, mites, weeds, and other pests and thus securing stable food production (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0015">Burger et al., 2008</a>). Additionally, climate and weather changes directly and indirectly affect crop production and pest reproduction, distribution, and migration. Thus, food production should be increased while reducing the use of chemicals (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0090">Porter et al., 1991</a>).Insects are rich in proteins (40&nbsp;%–70&nbsp;%), minerals, and vitamins, thus holding promise as alternative protein sources for the food industry (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0040">Gravel &amp; Doyen, 2020</a>). Over 2000 insect species are consumed in various countries, including those in Asia and Europe (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0135">van Huis, 2020</a>). The production of edible insects is more environmentally friendly and sustainable than livestock farming (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0030">FAO, 2013</a>), and the growth of the domestic and international insect market is expected to continue. Edible insects include members of the orders Lepidoptera, Coleoptera, Orthoptera, and Hymenoptera (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0145">Yoo et al., 2013</a>). In particular, the larvae of the mealworm beetle (Tenebrio molitor) have a protein content of 46.44&nbsp;% and are nutritionally rich alternative food sources (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0105">Ravzanaadii et al., 2012</a>). However, edible insects may contain harmful substances, such as microorganisms, chemicals, and parasites, with numerous studies reporting the detection of pesticides, including organophosphates and benzoquinones (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0010">Belluco et al., 2013</a>).Pesticides are toxic to humans and the environment and can harm the immune, reproductive, and nervous systems. In response to the concerns related to pesticide residues in agricultural products and human exposure (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0020">Damalas &amp; Eleftherohorinos, 2011</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0065">Lushchak et al., 2018</a>), the European Union (EU) has established 464 maximum residue limits to regulate pesticides in terrestrial invertebrates, including insects (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0025">EU, 2024</a>). In South Korea, the Rural Development Administration and Ministry of Food and Drug Safety set safety guidelines and residue limits for various crops, while the National Agricultural Products Quality Management Service and Ministry of Food and Drug Safety conduct safety investigations on harmful substances, including pesticide residues, in domestically produced and distributed agricultural products to ensure safe food production. However, no residue limits have been established for pesticides in edible insects in South Korea, which indicates the need to establish and monitor pesticide residue analysis methods, particularly for applying uniform PLS (positive list system) standards and future maximum residue limits.Owing to the high protein and fat contents of mealworm larvae, the analysis of pesticide residues therein requires pretreatment to prevent contamination (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0105">Ravzanaadii et al., 2012</a>), as exemplified by protein and fat removal based on the QuEChERS method and n-hexane treatment (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0045">Houbraken et al., 2016</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0100">Ramluckan et al., 2014</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0115">Shin et al., 2020</a>). Acetonitrile/hexane partitioning is necessary to improve the recovery rates of high-distribution-coefficient pesticides during gas chromatography-tandem mass spectrometry (GC–MS/MS) analysis (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0120">Shin et al., 2018</a>). Additionally, adsorbents commonly employed in the QuEChERS method, such as primary secondary amine (PSA), C18, Z-Sep, Z-Sep+, and HLB (hydrophilic lipophilic balance), should be used to remove potential interferents from the extract. Herein, we aimed to (i) develop a method for the simultaneous analysis of multiple pesticides and related metabolites in mealworm larvae using a GC–MS/MS–based modified QuEChERS approach and (ii) validate the effectiveness of this method by applying it to real mealworm larvae. The method improves routine residual pesticide analysis procedures to provide a breakthrough the analysis of high-protein and high-fat samples.<h4>2. Materials and methods</h4><h5>2.4. Instrumentation</h5>Pesticide analysis was performed using an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=7000C+triple-quadrupole">7000C triple-quadrupole mass spectrometer </a>coupled with an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=7890B+gas+chromatograph+">7890B gas chromatograph </a>(Santa Clara, CA, USA). The carrier gas (helium) was supplied at a flow rate of 1 mL/min. Samples were injected in the solvent vent mode, and the vent flow rate was held at 50 mL/min for the first 1.5 min, decreased to 25 mL/min, and maintained (5 psi) for 0.3 min. The target analytes were separated on an HP-5 ms column (30 m × 250 μm × 0.25 μm). The oven temperature was held at 50 °C for 3 min, increased to 185 °C at 30 °C/min, 250 °C at 5 °C/min, and 300 °C at 10 °C/min, and held for 7 min. The source and transfer line temperatures were set to 250 and 290 °C, respectively. Electron ionization was performed at 70 eV, and all pesticides were analyzed in the dynamic multiple reaction monitoring mode.<h4>3. Result and discussion</h4><h5>3.1.2. Partitioning efficiency</h5>Mealworm larvae have a fat content of 21.9&nbsp;wt% (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0055">Imathiu, 2020</a>) and should therefore be defatted prior to analysis to remove interferents and prevent the contamination of the GC–MS/MS instrument. Therefore, n-hexane, a nonpolar solvent effective for fat removal, was employed (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0100">Ramluckan et al., 2014</a>). Additionally, n-hexane (partition coefficient&nbsp;=&nbsp;3.90) has a higher affinity than acetonitrile (partition coefficient&nbsp;=&nbsp;−0.34) and can therefore extract nonpolar pesticides that may remain in the extraction solvent. Using n-hexane-saturated acetonitrile, we examined the effect of partitioning frequency on recovery rates (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#t0010">Table 2</a>). Each additional partitioning led to a higher pesticide recovery, with four partitions yielding a 22 percentage point increase in recovery (84.6&nbsp;%) compared with a single partition. At this level, 209 pesticides demonstrated acceptable recovery rates (70&nbsp;%–120&nbsp;%) and precisions (RSD&nbsp;≤&nbsp;20&nbsp;%). Thiocarbamate and organochlorine pesticides exhibited low recovery rates, probably because of their high partition coefficients (log P&nbsp;=&nbsp;4.1–6.9) due to their low polarities, and were therefore retained in the n-hexane phase (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0070">Mathieu et al., 2015</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0075">Mdeni et al., 2022</a>). However, the recovery rates of these pesticides increased with the increasing partitioning frequency (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#f0005">Fig. 1</a>). Therefore, partitioning with n-hexane-saturated acetonitrile was concluded to be essential for improving the recovery of pesticides with high partition coefficients, and the optimal number of partitions was identified as four.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Food_Chemistry_X_Volume_27_April_2025_102386_Fig_1_Recovery_rates_bars_and_partition_coefficients_log_P_triangles_of_10_representative_pesticides_2_79886fbb41.jpg" alt="Food Chemistry: X, Volume 27, April 2025, 102386: Fig. 1. Recovery rates (bars) and partition coefficients (log P, triangles) of 10 representative pesticides showing a strong dependence of recovery (>25 %) on the number of partitionings (N = 1, 2, 3, and 4). Error bars are the standard deviations of the recovery rates (n = 4)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Food_Chemistry_X_Volume_27_April_2025_102386_Fig_1_Recovery_rates_bars_and_partition_coefficients_log_P_triangles_of_10_representative_pesticides_2_79886fbb41.jpg 245w," sizes="100vw" width="1600" height="957"><h5>3.3. Real sample analysis</h5>Among the 24 samples collected from domestic mealworm larva farms, 11 contained the triazole fungicide triadimenol at concentrations of 14–996&nbsp;μg/kg (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#f0020">Fig. 4</a>) and were therefore noncompliant with the EU residue limit for terrestrial invertebrates (10&nbsp;μg/kg). Considering that the triadimenol residue limit for wheat, the primary ingredient of bran fed to mealworms, is 100&nbsp;μg/kg, pesticide absorption probably occurred through bran consumption. Thus, the established method for the multiresidue analysis of 247 pesticides in mealworm larvae was concluded to be applicable in field settings and enable both quantitative and qualitative analyses.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Food_Chemistry_X_Volume_27_April_2025_102386_Fig_4_Chromatograms_of_triadimenol_obtained_for_acetonitrile_control_pure_standard_2_c9e6bb0fed.jpg" alt="Food Chemistry: X, Volume 27, April 2025, 102386: Fig. 4. Chromatograms of triadimenol obtained for acetonitrile, control, pure standard (10 μg/kg), matrix-matched standard (10 μg/kg), and mealworm samples (6, 8, 15, 18, 20, 21, 22, 26, 28, 30, and 31)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Food_Chemistry_X_Volume_27_April_2025_102386_Fig_4_Chromatograms_of_triadimenol_obtained_for_acetonitrile_control_pure_standard_2_c9e6bb0fed.jpg 187w," sizes="100vw" width="1436" height="1200"><h4>4. Conclusions</h4>A GC–MS/MS–based multiresidue method for the detection and quantitation of 247 pesticides in mealworm larvae was developed, optimizing the standard QuEChERS procedure to account for matrix complexity and high fat content, and validated. Pesticide recovery rates were maximized by combining 0.1&nbsp;% formic acid in acetonitrile (extraction solvent) with the original QuEChERS packet. Further cleanup (PSA d-SPE) effectively removed matrix interferences without significant analyte loss, enhancing detection accuracy. According to the results of validation tests, the developed method exhibited high linearities, acceptable recovery rates, and low detection limits for most analytes and was therefore concluded to be robust and suitable for both quantitative and qualitative analyses. The analysis of 24 field samples revealed detectable levels of triadimenol, suggesting its potential uptake from bran feed. Thus, this validated approach was concluded to be suitable for application in regulatory and industrial settings, offering a reliable tool for monitoring pesticide residues in mealworm larvae and similar edible insect matrices.

GC–MS/MS–based multiresidue pesticide analysis in mealworm (Tenebrio molitor) larvae: Optimization of standard QuEChERS-based method to minimize matrix effects

Article

Product

Application

Scientific article

Science and research

Video

Poster

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

New Food magazine

Separation Science

Agilent Technologies

Thermo Fisher Scientific

Waters Corporation

In this webinar, we will discuss the necessity of regular updates for the Thermo Scientific Chromeleon software, as well as the transition to newer operating systems or database platforms to minimize support and security risks.To ensure the smooth operation and use of software, regular maintenance and updates are necessary. This structured software life cycle ensures that systems remain secure, efficient, and sustainable in the long term. Regular updates and continuous development are crucial to maintaining current security standards and compatibility.Our goal is to help you use an always up-to-date, secure, and high-performance Chromeleon CDS system. While migrating a single Chromeleon workstation is often straightforward, an enterprise-wide transition can present a much greater challenge in many cases. Learn how careful planning and structured coordination can make the transition smooth. We will show you how Thermo Fisher Scientific supports you in this process and works with you to achieve a successful update of your systems.In the second half of the webinar, Qpliance will share insights from over 100 Chromeleon configuration validations. They will focus on the practical implementation of the proven V-model using current regulations to achieve the highest audit security! Through professional project management and trustworthy collaboration, it is possible to reduce project duration by an average of 30%.<h4>Webinar topics:</h4><ul><li>Starting and executing a migration or update project&nbsp;</li><li>Goal definition - Do you need to improve performance, security, compatibility, or functionality? Do you need to comply with certain standards or regulations? Do you have a budget and a schedule?</li><li>Assessment of the current environment, including hardware, software, network, and user profiles – Identification of security gaps, dependencies, or compatibility issues&nbsp;</li><li>Implementation – What tools and options are available? What does a "best practice" approach look like?&nbsp;</li></ul><blockquote>Presenter: Michele Musu (Technical Sales Specialist for Chromatography and Mass Spectrometry Software, Thermo Fisher Scientific)Presenter: Christian Müller (Director of Operations)</blockquote>

Thermo Fisher Scientific: Migration and Update of the Chromatography Data System

Migration and Update of the Chromatography Data System

The necessity of regular updates for the Thermo Scientific Chromeleon software will be discussed.

It is critical for regulated laboratories to assess and vigilantly monitor risk to ensure patient safety. This can mean sifting through volumes of chromatography data system (CDS) data to find information that enables you to identify and assess potential risk, especially those associated with data integrity.In this webinar, our resident Empower Software expert Neil Lander is joined by guest Donald Preiss, Associate Director - IT Lab Applications, MannKind Corporation, who will provide insights into how the team at MannKind have overcome their data integrity challenges.They will also be joined by Ben Dearnaley, Principal Product Owner, Waters Corporation, to answer your questions about getting the most out of your CDS data by leveraging data analytics to generate valuable insights on data integrity and more.<h4>You will walk away with:</h4><ul><li>Insights into challenges faced by other organizations</li><li>Practical examples of what to monitor</li><li>Strategies for overcoming data integrity challenges</li></ul>Please join us for a lively discussion as we explore this topic. As always, please bring your questions for this exclusive opportunity to ask our experts anything you would like to know about Empower Software.<blockquote>Presenter: Neil Lander (Principal Product Manager, Informatics, Waters Corporation)Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.Presenter: Ben Dearnaley (Principal Product Owner, Connected Science, Waters Corporation)Ben has worked at Waters for 17 years, and 14 years in Pharma prior to that. His area of interest as both a customer and at Waters has been on how to leverage Empower meta-data into analytics and business intelligence which helps Empower stakeholders understand better how their laboratories are working, such as understanding system and resource utilization, laboratory workflows and potential data integrity issues. Ben was a key individual involved with EDS365 and is now working as a Cloud Product Owner with a focus on bringing Empower analytics into the Cloud.Presenter: Donald Preiss (Associate Director of IT Lab Applications, MannKind Corporation)Donny has held several positions at MannKind Corporation, most recently serving as Associate Director of IT Lab Applications.Donny has expertise in enterprise laboratory systems and is instrumental in ensuring compliance and providing reliable support for all software applications for the QC and R&amp;D laboratories. Donny manages the computer system validation (CSV) program and leads the IT-PMO. He has extensive experience in overseeing complex projects and driving organizational success.</blockquote>

Waters Corporation: Empower Tips: Ask Me Anything About Using CDS Data Analytics to Address Data Integrity Challenges

Empower Tips: Ask Me Anything About Using CDS Data Analytics to Address Data Integrity Challenges

In this webinar, Donald Preiss provide insights into how the team at MannKind have overcome their data integrity challenges.

Empower Tips - CDS Data Analytics to Data Integrity

Whether you are new to the practice of gas chromatography, or would like a refresher, the installation and care of your GC column is of the utmost importance.Join us as we discuss proper column installation and handling for all Agilent GCs including the Intuvo 9000. We will also address the common modes of column degradation and some of the misconceptions that people have concerning column degradation.Lastly, we will discuss ways that you can protect and maintain your column’s performance and extend its lifetime while minimizing instrument downtime.<blockquote>Presenter: Alex Ucci (Application Engineer, Agilent Technologies, Inc.)In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.Presenter:&nbsp;Ryan Birney (Application Engineer, Agilent Technologies, Inc.)In Ryan’s current role at Agilent, he provides application assistance and technical support for GC and Spectroscopy. He has been supporting Agilent in technical and sales roles for the past seven years. Ryan came to Agilent from industry, and has an BS degree in Biochemistry.</blockquote>

Agilent Technologies: Ensuring Peak Performance: Comprehensive Guide to GC Column Care

Ensuring Peak Performance: Comprehensive Guide to GC Column Care

Join us as we discuss proper column installation and handling for all Agilent GCs including the Intuvo 9000. 

Comprehensive Guide to GC Column Care

Join us for an insightful webinar on the advantages and best practices of using Hydrogen as a carrier gas with Gas Chromatography – Mass Spectrometry (GC/MS) instruments. This session will discuss several topics of critical importance when converting from Helium to Hydrogen carrier.Key Topics include:<ul><li>Safety considerations when using Hydrogen</li><li>Selecting the appropriate ion source</li><li>Choosing the right column for Hydrogen carrier gas</li><li>Understanding the effects of Hydrogen on analytical outcomes</li></ul>Whether you are new to GC/MS or looking to enhance your current setup, this webinar will equip you with the knowledge and tools to make informed decisions and improve your analytical results.<blockquote>Presenter: Alex Graettinger (GC/MS Data Acquisition Product Support Agilent)</blockquote>

Agilent Technologies: Becoming a Better Chromatographer - Educational Webinar Series

What to Consider for Success when Transitioning to Hydrogen Carrier Gas with GC/MS Instruments

Join us for an insightful webinar on the advantages and best practices of using Hydrogen as a carrier gas with GC/MS instruments. 

Transitioning to Hydrogen Carrier Gas with GC/MS

As you heat up your column, there is going to be some degree of bleeding. But sometimes we can have excessive or abnormal bleeding. There are also many misconceptions about column bleed and how it appears in your chromatogram. Join us as we distinguish between abnormal and normal bleed as well share some tips and tricks to control your bleed.<blockquote>Presenter: Alex Ucci (Application Engineer, Agilent Technologies, Inc.)In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.</blockquote>

Comprehensive Guide to GC Column Bleed: From Troubleshooting to Prevention

Join us as we distinguish between abnormal and normal bleed as well share some tips and tricks to control your bleed.

Comprehensive Guide to GC Column Bleed

Sample introduction is arguably one of the most important aspects in successful gas chromatography. The vast majority of problems that arise in GC are inlet or "front-end" related. If your sample is not introduced properly to the inlet and column, all bets are off for producing a useful high-resolution chromatogram. In this presentation we will discuss the various types of GC inlets available including when and how to use them.<blockquote>Presenter: Mark Sinnott (Application Engineer, Agilent Technologies, Inc.)Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Twin Falls Idaho.</blockquote>

Choosing the Right GC Inlet: Tailoring Your Method for Optimal Results

In this presentation we will discuss the various types of GC inlets available including when and how to use them

Choosing the Right GC Inlet

Whether you are new to GC or have been performing it for years, you may find that things just aren’t /going the way you want them to. There are many pitfalls that can cause problems and in this talk some of the topics we will discuss include:<ul><li>Problematic solvents</li><li>The importance of gas traps</li><li>Syringe hygiene</li><li>Front-end maintenance</li><li>Proper conditioning</li><li>Making connections</li><li>Importance of sample preparation</li></ul>Avoiding these pitfalls can help you achieve long-term reliable results.<blockquote>Presenter: Alex Ucci (Application Engineer, Agilent Technologies, Inc.)In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.</blockquote>

Common Pitfalls in GC Chromatography: What to Avoid

There are many pitfalls that can cause problems and in this talk some of the topics we will discuss 

In today’s fast-paced food production environment, manufacturers need more than just data—they need the ability to act on it instantly. This webinar will explore how Process NIR technology can drive smarter, faster decisions on the production line by enabling real-time process control and automation.As food processors face mounting pressure to reduce waste, maintain consistency, and respond to supply chain variability, the shift toward smarter, data-integrated operations is accelerating. Inline technologies like Process NIR are no longer limited to quality monitoring—they’re becoming central to automation strategies and Industry 4.0 transformation. This session will provide context for that shift and show how producers can move from data collection to actionable control.The webinar will address key challenges such as inconsistent product quality, high raw material losses, and the gap between data visibility and real-time action. Many producers collect production data, but lack the systems or integration needed to turn it into automated process improvements.Attendees will gain insights into how Process NIR fits into automation workflows, supports closed-loop control, and contributes to profitability. The session will cover trends like Industry 4.0, smart manufacturing, and digital transformation in food processing, with actionable strategies for implementation.The speakers will share a real-world example of how one processor improved efficiency and process stability using inline NIR technology in a high-throughput production environment. This example highlights how real-time data was used to make automatic adjustments, leading to tangible results.The speakers will provide practical tips for integrating Process NIR into existing systems, discuss common automation pitfalls, and answer live audience questions. They’ll also highlight how to evaluate readiness for automation and identify where real-time process control can deliver the most value.Key learning points:<ul><li>Discover how real-time process data can drive automation and reduce manual intervention in food production</li><li>Understand the role of Process NIR in supporting smarter, more consistent process control</li><li>Learn how leading processors are integrating NIR into their automation strategies for measurable gains</li><li>Explore the connection between Process NIR and Industry 4.0 trends in food manufacturing</li><li>Hear a real-world example of improved efficiency and control using inline NIR in high-throughput conditions</li><li>Ask our expert speakers your questions and gain practical advice for starting or scaling your automation journey</li></ul><blockquote>Presenter: Egbert Stärk (Principal Sales Specialist EMEAI, Perten)Presenter: Christian Müller (Principal Product Specialist, Perten)&nbsp;</blockquote>

New Food Magazine: From insight to automation: taking control with Process NIR

From insight to automation: taking control with Process NIR

Join webinar to explore how Process NIR technology enables real-time process control and automation

Food scientists face growing challenges in characterizing complex food matrices with conventional analytical methods, which often fall short in sensitivity, robustness, and dynamic range. In this webinar, Dr Natasha Spadafora demonstrates a flexible platform that overcomes these limitations using a cryogen-free focusing trap. She will share two case studies: using high-capacity sorptive extraction with automated re-collection to reveal honey authenticity markers across a wide dynamic range; and enhancing SPME analysis with enrichment to uncover the nutritional potential of Mediterranean macroalgae. These examples will showcase how a flexible sampling toolkit (via the Centri platform) and advanced chemometric analysis (via ChromCompare+ analytical software) can provide highly informative data, as well as higher throughput and more insight into results.<h5>By attending this presentation, you will:</h5><ul><li>Centri’s flexible sampling tools (multi-step enrichment, high-capacity sorptive extraction, automated re-collection) help discover more from food matrices.</li><li>Centri’s automated workflows reduce hands-on time, increase throughput, and improve reproducibility.</li><li>Intelligent data analysis tools can automatically identify key features that differentiate complex samples.&nbsp;</li><li>These features are applied in practice with case studies on honey fraud detection and algae nutrient profiling.</li></ul><blockquote>Presenter: Natasha D. Spadafora &nbsp;(Assistant Professor, University of Ferrara, Italy)Natasha D. Spadafora focuses her research on food science at the University of Ferrara. Her main interest is to develop end-to-end solutions in food quality, flavour, and fragrance (FFF) at a multidisciplinary level, including metabolomics, transcriptomics, and sensorial perception. &nbsp;Her research across academia and industry leverages advanced analytical techniques like GC (GCxGC)-MS and chemometrics to address real-world challenges in food authenticity and waste reduction. She specializes in translating complex data into actionable insights for the food supply chain.Presenter:&nbsp;Rebecca Cole (Application Specialist, Markes International, Wales)Rebecca Cole received a BSc in genetics from the University of Cardiff, UK, and subsequently did a PhD at the University of Bristol, where she wrote her thesis on the population genetics of parasitic nematodes. She is now an application specialist at Markes, providing technical and application support to users around the world and developing applications using extraction and enrichment techniques for GC–MS.</blockquote>

Separation Science: Expanding the Sample Extraction Toolkit for Food Analysis by GC-MS

Expanding the Sample Extraction Toolkit for Food Analysis by GC-MS

Discover a versatile platform for overcoming challenges in food analysis beyond conventional limits. 

Extraction Toolkit for Food Analysis by GC-MS

It is critical to keep your lab current and one of the ways to achieve this is by leveraging new features and functionality. In this session, we will explore new and upcoming Empower Software features, including:<ul><li>Updated functionality to simplify workflows requiring more stringent technical controls</li><li>New features to support expanded workflows</li><li>New data processing features and options</li></ul>Please join us for a lively discussion as we explore this topic. &nbsp;As always, please bring your questions for this exclusive opportunity to ask our experts anything about using Empower Software.<blockquote>Presenter: Neil Lander (Principal Product Manager, Informatics, Waters Corporation)Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.Presenter: Dr. Andy Meyer (Senior Application Scientist, Wyatt Technology)Dr. Andy Meyer joined Wyatt Technology in 2001, serving for several years as an Applications Scientist, then as Dean of Wyatt's "Light Scattering University" and as Director of Customer Service &amp; Support. After managing multiple regions in North America, Dr. Meyer is now a Senior Application Scientist for Wyatt. As a Wyatt customer, he completed his Ph.D. in Applied Science – Polymer Chemistry from the College of William and Mary in Virginia.</blockquote>

Waters Corporation: Empower Tips: Ask Me Anything About What's New in Empower Software

GCMS webinars focusing on Tips & Tricks | LabRulez GCMS