Broadband Laser-Based Infrared Detector for Gas Chromatography

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 30th September 2024? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring to you applications by Agilent Technologies, Waters Corporation, and Thermo Fisher Scientific, and a poster from <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/296">ASMS</a> by Shimadzu!<h4>1. Shimadzu: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/TP_093_Analysis_of_PFAS_in_Water_Final_05292024_8fa9fcb27d.pdf">Analysis of Volatile PFAS in Water Using Head-Space Solid Phase Microextraction- Gas Chromatography/Mass Spectrometry (HS-SPME GC/MS)</a></h4><ul><li>Poster / <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/296">ASMS</a>&nbsp;</li></ul>Introduction&nbsp;Per- and Polyfluoroalkyl Substances (PFAS) are environmental pollutants with recognized health and environmental concerns due to their probable toxicity, persistence, and ubiquitousness throughout the environment, and consumer and industrial products. PFAS encompass a large family of chemicals with varying physicochemical properties. These properties not only affect their toxicity and environmental fate, but also complicates chemical analysis.In this work, a Head-Space Solid Phase Microextraction-Gas Chromatography/Mass Spectrometry (HS-SPME GCMS) analytical method was developed to analyze six classes of volatile PFAS in water. This HS-SPME method presents the advantage of simplifying sample extraction and handling for the analysis of volatile PFAS in water, hence, minimizing operational costs, potential errors, and risk of sample-cross contamination.ConclusionThis study demonstrated the use of a Shimadzu GC/MS-QP2020 NX single quadrupole instrument configured with the AOC-6000 Plus multifunctional autosampler and an automated head space solid phase microextraction unit for measurement of volatile PFAS compounds in water. Linear calibration curves were obtained for all compounds (R 2 ≥ 0.993 and RF %RSD &lt; 20 %). The HS-SPME GC/MS-QP2020 NX method demonstrated qualitative and quantitative capability of analyzing PFAS compounds.<h4>2. Thermo Fisher Scientific: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_003028_gc_ms_isq_epa_vocs_an003028_na_en_7646797ef5.pdf">Analysis of volatile organic compounds in drinking water according to U.S. EPA Method 524.4</a></h4><ul><li>Application</li></ul>GoalDemonstration of an analytical method that meets the requirements outlined in U.S. EPA Method 524.4 for the quantitation of volatile organic compounds (VOCs) in drinking water, using the Teledyne LABS Tekmar Lumin Purge and Trap (P&amp;T) concentrator paired with the AQUATek LVA autosampler system along with a Thermo Scientific™ ISQ™ 7610 MS system coupled with a Thermo Scientific™ TRACE™ 1610 gas chromatograph (GC) and Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS). Target analyte linearity, method detection limit (MDL), minimum report level (MRL), and mid-point precision and accuracy were assessed to evaluate method performance.Keywords: EPA, U.S. EPA 524.4, VOCs, phthalates, trace analysis, gas chromatography, single quadrupole mass spectrometry, selected ion monitoring, sensitivity, GRO, THM, volatiles, environmental lab, environmental sample analysis, analytical testing laboratories, ISQ 7610 MS, TRACE 1610 GC, GC-MS.IntroductionVolatile organic compounds (VOCs) are man-made contaminants in various products that pose environmental and public health risks. These compounds are regulated in drinking water, and laboratories follow regulations including U.S. EPA Method 524.2.1 A previous application note described U.S. EPA Method 524.2,2,3 which is the most common method for VOC water testing in the USA. U.S. EPA Method 524.4 is an updated method that allows for nitrogen to be used as the purge gas, thus reducing helium consumption, and is now being more widely used. Targeting 75 VOCs, this method differs by offering more method parameter flexibility but stricter quality control, including the stringent calculation of the minimum reporting level for evaluating calibration checks.Implementing U.S. EPA Method 524.4 can present multiple challenges for laboratories. Striking a balance between optimized method conditions and meeting the acceptance criteria, like detection limit requirements for various compound concentrations, is pivotal. Another major hurdle is managing the water matrix to minimize GC-MS system water introduction, which could lead to detrimental effects and delay sample reporting, thereby increasing public safety risks. Ultimately, maintaining consistency in test results to avoid sample reanalysis is crucial. Another factor for laboratories to consider is the fluctuating cost of helium, which is the analytical gas of choice for this analysis. Reducing the use of helium—a limited resource—will enable the laboratory to reduce operational costs and increase profitability.The following evaluation describes the use of the ISQ 7610 GC-MS system coupled with a TRACE 1610 GC with the Thermo Scientific™ HeSaver-H2Safer™ split/splitless injector and Teledyne LABS Tekmar Lumin P&amp;T concentrator paired with the AQUATek LVA autosampler for U.S. EPA Method 524.4.ConclusionThe combined solution of the TRACE 1610 GC coupled with the ISQ 7610 system and the Tekmar Lumin P&amp;T concentrator with the AQUATek LVA autosampler system successfully addresses the challenges of VOC analysis and provides a robust, sensitive solution needed for ensuring maximized sample throughput and regulatory method compliance for U.S. EPA Method 524.4.<ul><li>Excellent linearity for all compounds was demonstrated with the linear regression (r²≥0.995) of the calibration response factors passing all method requirements.</li><li>MDL and precision for seven 0.5 ppb standards showed no interference from excessive water and produced very reproducible results.</li><li>The precision for n=30 samples over 245 injections displayed &lt;30% RSD for all compounds as the method requires and an average recovery of 91%.</li><li>Utilizing HeSaver-H2Safer technology reduced helium consumption for the method by 4 times, which provides a significant cost savings.</li></ul><h4>3. Waters Corporation: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/720008298_en_db4158391c.pdf">Extractables Analysis of Nasal Spray Devices Using Gas Chromatography and High- Resolution Mass Spectrometry With Soft Ionization</a></h4><ul><li>Application</li></ul>AbstractDue to concern about the safety of components from plastic, it is crucial to screen for and identify potential extractables and leachables (E&amp;L) in pharmaceutical packaging and medical devices. For volatile, and semi-volatile compounds, gas chromatography-mass spectrometry (GC-MS) with electron ionization (EI) is typically used. Compounds are determined using scientific libraries; however, where compounds are not listed or where the sensitivity of EI-MS is not sufficient, the identification process becomes challenging.Here, we describe an E&amp;L screening experiment using gas chromatography and a quadrupole time of flight high-resolution mass spectrometer (QToF-HRMS) with atmospheric pressure gas chromatography (APGC) for soft ionization. A data independent acquisition (DIA) strategy is utilized to aid screening and elucidation which are combined in a screening software solution.Benefits<ul><li>GC-QToF MS with APGC as an orthogonal technique to LC-QToF-MS allows for comprehensive compound coverage with increased sensitivity compared to typical EI techniques</li><li>The UNIFI™ application within the waters_connect™ platform provides customized workflows to simplify screening and structural elucidation in complex datasets</li><li>The Xevo™ G3 QTof Mass Spectrometer enables confident identification of E&amp;L components in complex matrices through novel ion optics and detection system which maximize transmission</li><li>Soft ionization using the APGC™ source allows for the detection of molecular ions from which elemental compositions can be derived to aid compound identification and confirmation&nbsp;</li><li>MSE, a data independent acquisition, increases confidence in identifications when screening against a library and provides additional information to aid structural elucidation</li></ul>Conclusion&nbsp;When undertaking E&amp;L screening analyses it is important to use a range of analytical techniques to account for different compound chemistries. GC-QToF MS with APGC as an orthogonal technique to LC-QToF-MS allowed for comprehensive compound coverage with increased sensitivity compared to typical EI techniques. Due to the soft ionization of APGC, the intact molecular ion is often present in the spectra. This combined with a data independent acquisition, MSE mode, utilizes full spectral acquisition of the accurate mass information of both precursor and fragment ions.This approach boosts confidence in component identifications when screening against an MS/MS library, while minimizing false positives. For instance, in the LC-QToF-MS there were just under 40 potential compounds matches in sample E48 after considering factors such as retention time match, mass accuracy below 3 ppm, and the presence of at least one fragment ion. A further 38 compound matches in sample E48 were tentatively identified using GC-QToF MS with APGC, with mass accuracy below 3 ppm, and the presence of at least one fragment ion.MSE data also aids in the structural elucidation of unknown substances by utilizing accurate mass and corresponding fragment ions, facilitating comprehensive characterization. This data increases confidence in identifications of components and assists with structural elucidation of unknowns to ultimately aid full characterization. For example an unknown with protonated m/z 284.2703 was tentatively identified as a N-(2-(1-piperazinyl)ethyl)decanamide (mass error 2.33 ppm) by the software.For the extractables analysis of nasal sprays the UNIFI application within the waters_connect platform provided SST benchmarking, screening against a library, summary plots to identify trends, filtering of AET levels, binary compare mode to isolate relevant unknowns, and a Discovery Tool for elucidation of unknowns.<h4>4. Agilent Technologies: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_voc_rubber_gasket_extracts_gc_msd_5994_7777en_agilent_6a0a6bf7d0.pdf">Analysis of Volatile Compounds Identified in Rubber Gasket Extracts Using GC/MSD and High-Resolution GC/Q-TOF</a></h4><ul><li>Application</li></ul>AbstractChemicals that are part of polymeric container closure systems (CCS) and drug delivery systems have the potential to migrate into drug products during manufacturing, storage, transport, and delivery, and must be identified in the final products to ensure their safety.This application note presents a rubber gasket extractables study using a unit mass resolution gas chromatography/mass selective detector (GC/MSD) and a high-resolution gas chromatography/quadrupole time-of-flight (GC/Q-TOF) mass spectrometer to establish a process for identifying GC-amenable extractables and leachable (E&amp;L) compounds.IntroductionElastomeric gaskets, plungers, and O-rings are common sources of leachable compounds in the manufacturing, storage, and delivery of drug products. E&amp;Ls derived from elastomeric components may impact the stability and efficacy of small and large molecule drug products1, and therefore need to be characterized thoroughly. Exposure to some E&amp;L chemicals, such as phthalates and nitrosamines, even at low levels, may cause safety concerns.2 Chemicals derived from the elastomer manufacturing process typically include accelerators, activators, antioxidants, fillers, plasticizers (including phthalates), mold release agents, and other additives3 that may leach into the final product. Some additives present in elastomer packaging materials may also contain polycyclic aromatic hydrocarbons (PAHs)4 and aliphatic hydrocarbons.GC/MS is a commonly used technique for analyzing volatile and semivolatile organic compounds in the E&amp;L space. This study demonstrates the capabilities of GC/MSD to identify GC-amenable compounds present in a solvent extract of a rubber gasket by leveraging chromatographic deconvolution in combination with retention index (RI)-based filtering. Adding a high-resolution accurate mass GC/Q-TOF into the E&amp;L workflow provided a higher number of identified chemicals. It also increased confidence in compound identification and enabled structure elucidation of unknown compounds.The study was performed in the Network Workstation configuration using Agilent OpenLab Electronic Content Management (ECM) XT as the data repository. This configuration enabled tools that facilitate compliance with various national and EU electronic record regulations, including audit trails, user authentication, role-based permission controls, and remote data storage.5ConclusionThe GC/MSD is an effective and accessible tool for the analysis of volatile and semivolatile compounds in complex E&amp;L extracts. The established workflow includes deconvolution and an RI-based library search with the data acquisition performed in a compliant environment.The high-resolution Agilent 7250 GC/Q-TOF enabled the identification of additional components with increased confidence, as well as structure elucidation of the unknown compounds.Furthermore, using the novel ultra-low bleed Agilent J&amp;W DB-5Q GC column resulted in a significant decrease in background, which helps in the identification of late-eluting compounds.

News from LabRulezGCMS Library - Week 40, 2024

NIST, Wiley, and user-created EI mass spectral libraries are very powerful tools for the identification of organic compounds in complex mixtures by gas chromatography-mass spectrometry (GC-MS). &nbsp;This series of webinars will demonstrate the use of the NIST software suite including the NIST Search, AMDIS, and MS Interpreter for searching EI libraries. The series should be useful to a wide variety of research and developmental scientists involved in medical, environmental, industrial, forensic, and biological disciplines.<blockquote>The webinars demonstrate both Versions 3.0 (2023) and V2.4 of the NIST search. If you are using V3.0, start with Part 0. If you are using V2.4, start with Part I.</blockquote><h5>Today, we will look at:</h5><h3>Part V: Creating and Sharing User EI and MS/MS Libraries</h3><ul><li>Help Files for NIST Search</li><li>General Windows commands/functions</li><li>Creating a user library spectrum</li><li>Creating a user library spectrum: opening edit spectrum</li><li>Creating a user library spectrum: spectrum information window</li><li>Creating a user library spectrum: adding comments and synonyms</li><li>Creating a user library spectrum: using windows notepad and tags</li><li>Creating a user library spectrum: comment field display with user tags</li><li>Creating a user library spectrum: comment field display showing user tags</li><li>Tags included with Wiley libraries</li><li>Possible quality checks before adding spectra to user libraries</li><li>Addition of spectrum to user library or creating new library</li><li>(Re)Index Indices for structure, hybrid search and InChIKey for user library</li><li>NIST formatted user libraries at Eastman Chemical Company</li><li>Software essentials and approach</li><li>Excerpt of typical DOS script used in approach</li><li>Webinar References</li><li>Acknowledgements</li></ul><blockquote>Detailed Handouts including tables of content are available in the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ei_user_libraries_pt_v_2_cc2179c747/ei_user_libraries_pt_v-2.pdf">LabRulezGCMS library</a></blockquote><h4>Other parts of this series are focused on:</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=KppCCeYTWTU">Part 0: Changes in EI NIST23 Program (V3.0)</a> (video only)</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4438">Part I: Spectral Searches with NIST MS Search</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4463">Part II: Structure Searches with MS Search and Using MS Interpreter</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4494">Part III: AMDIS (NIST) for Processing EI Mass Spectral Data Files</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4528">Part IV: Advanced NIST Hybrid Search of EI and MS/MS Spectra</a></li><li>Part V: Creating and Sharing User EI and MS/MS Libraries (this part)</li><li>Part VI: Creating and Using Retention Indices in NIST Software</li><li>Part VII: &nbsp;Tracking Complex Coelution with AMDIS and NIST Search</li></ul><h4>Higher quality videos can be downloaded here:</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://drive.google.com/file/d/1XGOnO6vwyJv6rPucIH-NgOTBdvH1jNDg/view?usp=sharing">Higher Quality Video Part 0</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://drive.google.com/file/d/116Gzyh9nT4iDfJkac20K9aYarGvxpV2e/view?usp=sharing">Higher Quality Videos Pt. I-V Zipped</a></li></ul><h4>Other Webinar Resources:</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://drive.google.com/file/d/1EGlEubUOWiNy3Y3mQZWdoaUXsFKTNjjj/view?usp=sharing">Test Files Used In Part VII for Tracking Coelution in Complex Mixtures with AMDIS and NIST</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2023/04/27/nist2023-library-and-software-available-in-early-june/">New NIST23 Brochures and Purchasing</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/wp-content/uploads/2023/07/nist_2023_release_presentation.pdf">NIST23 ASMS Presentation Houston, TX</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://blog.sepscience.com/massspectrometry/nist-23">NIST 23 Separation Science Article by David Sparkman</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2020/08/20/most-current-user-manuals-for-nist-search-and-amdis/">NIST and AMDIS User Manuals</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2020/08/20/most-current-user-manuals-for-nist-search-and-amdis/">NIST Approach for Creating Libraries</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2020/08/20/most-current-user-manuals-for-nist-search-and-amdis/">Databases Listed in Version 3.0 (2023)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.acdlabs.com/resources/free-chemistry-software-apps/chemsketch-freeware/">ACD Free Software</a> (structure drawing program personal/academic use)</li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2023/04/free-drawing-program-mass-spec-calculator-professional/">Mass Spec Calculator Professional</a> (free structure drawing program)</li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2011/08/28/using-nist-search-program-with-data-processing-and-drawing-programs/">Using with Manufacturers Data Processing Software</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2020/10/11/excel-deltamass-table-for-hybrid-searches/">Delta Mass Table (Excel Format)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/wp-content/uploads/2023/05/deltamass_ei.pdf">Delta Mass Table (PDF format)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2023/01/25/unknown-identification-presentation-at-current-trends-in-seized-drugs-analysis-symposium/">Hybrid Search/ChemSpider/SciFinder for Illicit Drug Identifications</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2011/08/28/using-nist-search-program-with-data-processing-and-drawing-programs/">Importing Mass Spectra to NIST Search Program</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2021/01/31/nist-ms-interpreter/">MS_Interpreter Correlating Structure to Spectrum</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2020/09/21/nists-suggested-settings-for-amdis-filter-settings/">NIST Tutorials and Settings for AMDIS</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2020/09/20/using-example-file-and-spectra/">Example Files for Part III AMDIS Webinar</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2020/09/20/using-example-file-and-spectra/">Example Spectra/Structures in Library Format Parts I-V</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/wp-content/uploads/2020/09/wiley_usermanual.pdf">Wiley Library User Manual with Spectral Source Codes</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/2011/08/28/using-nist-search-program-with-data-processing-and-drawing-programs/">Using with Manufacturers Data Processing Software</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/wp-content/uploads/2020/12/observations-on-spectra-in-mona-database.pdf">Components in Free MONA Libraries</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://drive.google.com/file/d/1kGdFVnYYmrE-n1trB6ngVRPrSgyHsEx7/view?usp=share_link">MONA Library in EI format</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://drive.google.com/file/d/1os21j4L87oUmQ8GhQcIvX4edk6014JJ5/view?usp=drive_link">MONA and Other Free Libraries, 60,829 EI Spectra</a> (see read_me in zip file)</li></ul>

Effective Use of EI Mass Spectral Databases in Unknown Identifications - Part V: Creating and Sharing User EI and MS/MS Libraries

Article

Application

Poster

Scientific article

Video

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

Teledyne LABS

Thermo Fisher Scientific

<h5>The following will be covered during the webinar:</h5>
<ul>
<li>Combining tips from the Method Optimization Series and Moisture Control Webinars to help you build an optimized P&amp;T and GC/MS method to improve analyte recovery</li>
<li>Step by step guide on how to build an optimized specialized method including Mold and Odor analysis, Wisconsin GRO, 1,4-Dioxane and Epichlorohydrin.</li>
</ul>
<h3>Who should attend this webinar:</h3>
<ul>
<li>Anyone working with wastewater or drinking water purge and trap methods</li>
<li>Any scientist or analyst that wishes to learn more about method optimization</li>
<li>Any scientist or analyst that wishes to learn tips on improving analyte recovery</li>
<li>Environmental scientists/technicians, analytical chemists/technicians, laboratory managers</li>
</ul>
<blockquote>
Presenter: Amy Nutter (Sr VOC Applications Chemist)
</blockquote>
<blockquote>
Amy Nutter is a senior VOC applications chemist at Teledyne Tekmar. Currently, she is focused on applications development and customer application support on the Purge and Trap product line. Previous to her current role, Amy worked for the city of Cincinnati in both the drinking water and wastewater laboratories.
</blockquote>

Teledyne Tekmar: Building Your Optimized VOC Method

Building Your Optimized VOC Method

Join us for this complimentary webinar where you have an introduction to EPA Method 624. Attendees will get a brief understanding of Purge and Trap as well as an understanding of EPA Methods 624 and analysis for municipal and industrial wastewater.
<h5>This webinar will cover the following:</h5>
<ul>
<li>Purge and Trap Theory</li>
<li>EPA Method 624</li>
<li>Challenges and Tips</li>
</ul>
The webinar is designed for analysts looking to gain a brief introduction to the EPA method 624 analysis. How it works. The processes involved. 
<blockquote>
Presenter: Jeramiah Bradley (Applications Chemist)
</blockquote>
<blockquote>
Jeramiah Bradley is a VOC applications chemist at Teledyne Tekmar. Currently, he is focused on application development and customer application support on the Purge and Trap product line. Previous to his current role, Jeramiah worked for Coca Cola Consolidated as a Quality Assurance Chemist conducting qualitative and quantitative testing of beverage samples.
</blockquote>

Pixabay/Jouregio: Introduction to EPA Method 624 - Level 101

Introduction to EPA Method 624 - Level 101

Join us for this complimentary webinar in our Troubleshooting series. Attendees will learn tips to help overcome purge and trap system leaks.
The following will be covered during the webinar:
<ul>
<li>To be added shortly</li>
</ul>
<blockquote>
Presenter: Amy Nutter (Sr VOC Applications Chemist)
</blockquote>
<blockquote>
Amy Nutter is a senior VOC applications chemist at Teledyne Tekmar. Currently, she is focused on applications development and customer application support on the Purge and Trap product line. Previous to her current role, Amy worked for the city of Cincinnati in both the drinking water and wastewater laboratories.
</blockquote>

Teledyne Tekmar: Troubleshooting Series: Purge and Trap System Leaks

Troubleshooting Series: Purge and Trap System Leaks

Experience the productivity evolution and discover new GC innovations designed to help analytical testing laboratories to stay ahead of their everyday challenges. We will showcase a new lineup of GC and GCMS systems that enable analytical testing laboratories to maximize sample throughput, increase instrument uptime and achieve a rapid return on investment.
Hear from experts working in the field of environmental, food and pharmaceutical testing and how the new technology helped them stay ahead in their pursuits with measurably more production and unstoppable confidence in results.
<h3>Learning objectives</h3>
<ul>
<li>Learn about innovations offered by the new GC and GCMS systems</li>
<li>Understand how the new technology helps meet and exceed regulatory compliance requirements in addition to increased laboratory productivity</li>
<li>Hear from experts in the field of environmental, food and pharmaceutical testing how the new technology has impacted their daily workflow</li>
</ul>
<h3>AGENDA</h3>
<h4>Session 1: The Reveal</h4>
<ul>
<li>Date: Tuesday, March 08, 2022</li>
<li>Time: 9:30 AM Central European Time</li>
<li>Duration: 1 hour</li>
</ul>
<h5>Welcome</h5>
<ul>
<li>Fabrizio Moltoni (VP and GM Analytical Business Technologies, Thermo Fisher Scientific)</li>
</ul>
<h5>Stay ahead with measurably more production</h5>
<ul>
<li>Daniela Cavagnino (Global Product Marketing Manager, Thermo Fisher Scientific)</li>
</ul>
<h5>Stay ahead with unstoppable confidence</h5>
<ul>
<li>Adam Ladak (Global Product Marketing Manager, Thermo Fisher Scientific)</li>
</ul>
<h5>Product Demo</h5>
<ul>
<li>Giulia Riccardino (Senior GC/GC-MS Applications Specialist, Thermo Fisher Scientific)</li>
</ul>
<h5>Q&amp;A</h5>
<h4>Session 2: Applied Technology</h4>
<ul>
<li>Date: Tuesday, March 08, 2022</li>
<li>Time: 10:45 AM Central European Time</li>
<li>Duration: 1 hour The impact of smooth method transfer in a pharmaceutical Quality Control laboratory Thomas Schott, Dr. Willmar Schwabe</li>
</ul>
<h5>Uninterrupted analysis of volatile organic compounds in accordance with EPA and worldwide regulations</h5>
<ul>
<li>Amy Nutter (Teledyne Tekmar)</li>
</ul>
<h5>Unstoppable analysis of pesticides residues in black tea using a new triple quadrupole GC-MS</h5>
<ul>
<li>Camille Grigsby (NOW Foods)</li>
</ul>
<h5>Q&amp;A</h5>

Thermo Scientific: INNOVATION SUMMIT 2022 - Stay ahead with new GC and GCMS technology

Stay ahead with new GC and GCMS technology: INNOVATION SUMMIT 2022

We will showcase a new lineup of GC and GCMS systems that enable analytical testing laboratories.

Stay ahead with new GC and GCMS technology 2022

Anyone working with soil, wastewater, and/or drinking water Purge &amp; Trap methods will learn from the expertise and experience shared during this 30-minute webinar. You’ll discover more about Purge &amp; Trap analysis and troubleshooting in a half hour than you could anywhere else. Learn how to isolate system components, from the autosampler on the Purge &amp; Trap to the mass spectrometer, to resolve common problems that can occur during volatiles analysis.
To register, just choose a convenient time below. We look forward to speaking with you!
<blockquote>
Presenter: Amy Nutter (Volatile Organic Compound (VOC) technical product specialist at Teledyne Tekmar)
</blockquote>
<blockquote>
Currently, Amy is focused on applications development and customer application support on the Purge &amp;Trap product line. She formerly worked for the city of Cincinnati, Ohio, in both the drinking water and wastewater laboratories.
</blockquote>

Teledyne Tekmar: Troubleshooting any Purge & Trap for VOC Analysis

Troubleshooting any Purge & Trap for VOC Analysis

You’ll discover more about Purge & Trap analysis and troubleshooting in a half hour than you could anywhere else.

<h5>Join us Wednesday, June 21, for this information-packed, 30-minute webinar to learn</h5>
<ul>
<li>Fundamentals of Purge and Trap: what it is and how it works</li>
<li>Requirements of a trap and how they adsorb and release volatile compounds</li>
<li>Purge gas selection</li>
<li>The effects of purge parameters on purge efficiency</li>
</ul>
This is a must-attend session if:
<ul>
<li>You work with purge and trap methods in the soil, wastewater and/or drinking water fields</li>
<li>Are a scientist or analyst wishing to learn more about P&amp;T analysis </li>
<li>Are an environmental scientist/technician, analytical chemist or lab manager</li>
</ul>
<blockquote>
Presenter: Amy Nutter (the VOC technical product specialist at Teledyne Tekmar)
</blockquote>
<blockquote>
Amy currently is focused on OEM and customer technical training and application support on the Purge and Trap product line. Previously, Amy worked for the City of Cincinnati in both the drinking water and wastewater laboratories.
</blockquote>
To attend, please select the time on Wednesday, June 21, that works best for you. We look forward to sharing this valuable information.

Teledyne Tekmar: Fundamentals of Purge & Trap

Fundamentals of Purge & Trap

Fundamentals of Purge and Trap. Requirements of a trap. Purge gas selection. The effects of purge parameters on purge efficiency...

In today’s economy, the price for everything is on the rise. Helium is becoming increasingly more expensive and harder to source, making it a less desirable purge gas for the Purge &amp; Trap process. The good news is, there are less expensive, easier to obtain alternatives that get the job done. And if helium remains your gas of choice, there are budget-friendly methods for conserving it during analysis. 
We welcome you to join us as Teledyne Tekmar, designer and manufacturer of analytical instrumentation for laboratories, presents this 30-minute webinar hosted by Amy Nutter, Teledyne Tekmar’s VOC technical product specialist.
During the webinar, you will gain expert insight into:
<ul>
<li>What Purge &amp; Trap is and how it works</li>
<li>Alternative purge gases that can be used during the Purge &amp; Trap process</li>
<li>Purge gas comparisons</li>
<li>Comparisons of different purge parameters with helium conservation in mind</li>
</ul>
Who should attend this webinar (Audience profile/ experience):
Anyone working with soil, wastewater, and/or drinking water in an organic laboratory will benefit from taking 30 minutes to save money and conserve helium. This includes:
<ul>
<li>Any scientist or analyst that wishes to learn more about Purge &amp; Trap analysis</li>
<li>Environmental scientists/technicians</li>
<li>Analytical chemists/technicians</li>
<li>Laboratory managers</li>
</ul>
<blockquote>
Presenter: Amy Nutter (Teledyne Tekmar’s VOC technical product specialist)
</blockquote>

Teledyne Tekmar: Helium Conservation in Purge & Trap Analysis

Helium Conservation in Purge & Trap Analysis

What Purge & Trap is and how it works. Alternative purge gases that can be used during the Purge & Trap process. Purge gas comparisons.

If you are involved at any level of responsibility in the VOC analysis of drinking water by P&amp;T, whether new to the technique or more advanced, and would like to optimize the process, this informative 30-minute webinar is for you.
We’ll quickly review the fundamentals, followed by an overview of U.S. Environmental Protection Agency 524 method requirements for drinking water samples. We’ll address the challenges and solutions for drinking water methods, and discuss the method parameters to select for the most efficient purge of drinking water samples.
Your presenter will be Amy Nutter, VOC technical product specialist at Teledyne LABS. Amy looks forward to sharing her expertise with you to use the best techniques to gain consistently accurate results in your lab.
<blockquote>
Presenter: Amy Nutter (VOC technical product specialist at Teledyne LABS)
</blockquote>

Teledyne: VOC Analysis of Drinking Water by Purge and Trap

VOC Analysis of Drinking Water by Purge and Trap

Review of the fundamentals of VOC analysis of drinking water, followed by an overview of U.S. Environmental Protection Agency 524 method requirements.

<h3>The following will be covered during the webinar:</h3>
<ul>
<li>Why is water vapor bad for common purge and trap methods?</li>
<li>How do we deal with it?</li>
<li>Method Optimization</li>
</ul>
<h3>Who should attend this webinar:</h3>
<ul>
<li>Anyone working with wastewater or drinking water purge and trap methods</li>
<li>Any scientist or analyst that wishes to learn more about selecting equipment and consumables</li>
<li>Any scientist or analyst that wishes to learn tips on moisture control</li>
<li>Environmental scientists/technicians, analytical chemists/technicians, laboratory managers</li>
</ul>
<blockquote>
Presenter: Amy Nutter (Sr VOC Applications Chemist)
</blockquote>
<blockquote>
Amy Nutter is a senior VOC applications chemist at Teledyne Tekmar. Currently, she is focused on applications development and customer application support on the Purge and Trap product line. Previous to her current role, Amy worked for the city of Cincinnati in both the drinking water and wastewater laboratories.
</blockquote>

Tekmar Teledyne: Purge and Trap Moisture Control Tips with the Atomx XYZ and Luminv

Purge and Trap Moisture Control Tips with the Atomx XYZ and Lumin

We will compare the processes, methods and consistent accuracy using the Atomx XYZ Multi-matrix Concentrator.
<h3>This webinar will cover the following:</h3>
<ul>
<li>Purge and Trap Theory</li>
<li>Changes made from EPA Method C to D</li>
<li>Results of each method using prep method 5030 vs 5035</li>
<li>Challenges and Tips</li>
</ul>
The webinar is designed for analysts looking to understand EPA method 8260 C &amp; D for wastewater metrices, how it works and the process involved.
<blockquote>
Jeramiah Bradley (Applications Chemist)
</blockquote>

GCMS webinars focusing on Purge and Trap | LabRulez GCMS