Evaporation is a fundamental process in chemistry and laboratory settings, essential for concentrating solutions, purifying compounds, and drying samples. While traditional evaporation relies on heat to remove solvents, evaporation under vacuum offers a more efficient and versatile approach. By reducing the pressure, vacuum evaporation lowers the boiling point of solvents, allowing for faster and safer evaporation at lower temperatures. This article explores when and why evaporation under vacuum is helpful, highlighting its advantages, applications, and key considerations.<h3>Understanding Evaporation Under Vacuum</h3>Evaporation under vacuum, also known as vacuum evaporation, involves reducing the atmospheric pressure around a liquid, which decreases its boiling point. This allows the solvent to evaporate at a lower temperature than it would under normal atmospheric conditions. The process typically employs equipment like rotary evaporators and vacuum ovens, which create a controlled low-pressure environment to facilitate efficient solvent removal.<h4>How It Works:</h4><ul><li>Pressure Reduction:&nbsp;A vacuum pump reduces the pressure in the system.&nbsp;</li><li>Lower Boiling Point:&nbsp;The reduced pressure lowers the boiling point of the solvent.&nbsp;</li><li>Evaporation:&nbsp;The solvent evaporates at the lower temperature, leaving behind the concentrated sample or dried product.</li></ul><h3>Advantages of Vacuum Evaporation&nbsp;&nbsp;</h3><h4>Enhanced Efficiency and Speed&nbsp;</h4>Vacuum evaporation significantly speeds up the solvent removal process. The lower boiling point means that solvents evaporate more quickly, reducing the time required for concentration or drying.<h4>Lower Temperatures</h4>Evaporating at lower temperatures is crucial for preserving thermally sensitive compounds that might degrade under higher heat. This is particularly important in pharmaceutical and biochemical applications.<h4>Improved Safety&nbsp;</h4>By avoiding high temperatures, vacuum evaporation reduces the risk of thermal decomposition and hazardous reactions. It also minimizes the potential for solvent vapors to become flammable or explosive.<h4>Reduced Solvent Usage and Waste&nbsp;</h4>Vacuum evaporation often requires less solvent and generates less waste. This is beneficial for both cost savings and environmental sustainability. For example, Organomation <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=338&amp;distributorItems=332&amp;search=evap">large scale evaporators</a> are capable of recollecting up to 97% of starting solvent.<h3>Applications in Laboratory Settings&nbsp;</h3><h4>Sample Concentration&nbsp;</h4>Vacuum evaporation is widely used to concentrate samples for analytical techniques such as <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/hplc-sample-preparation">high-performance liquid chromatography</a> (HPLC) and <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-gc-ms/ms-analysis">gas chromatography-mass spectrometry</a> (GC-MS). Concentrating the sample improves the detection limits and accuracy of these methods.<h4>Drying Samples</h4>It is also employed for drying samples before further analysis or storage. Removing moisture is crucial for accurate weight measurements and preventing degradation of sensitive compounds.<h4>Preparation for Crystallization&nbsp;</h4>In crystallization studies, vacuum evaporation can be used to concentrate solutions to supersaturation, facilitating the formation of crystals.<h3>Industrial Applications of Vacuum Evaporation&nbsp;</h3><h4>Environmental Analysis&nbsp;</h4>In environmental labs, vacuum evaporation concentrates pollutants from large volume water samples, allowing for more accurate detection and quantification of contaminants<h4>Chemical Manufacturing&nbsp;</h4>Vacuum evaporation is employed in chemical manufacturing for solvent recovery and recycling, reducing costs and environmental impact.<h4>Pharmaceutical Industry&nbsp;</h4>In pharmaceutical manufacturing, vacuum evaporation is essential for purifying active pharmaceutical ingredients (APIs) by removing solvents and other impurities without degrading the product.<h4>Food and Beverage Industry&nbsp;</h4>The food industry uses vacuum evaporation to concentrate flavors and extracts. This process enhances the intensity of flavors while preserving the quality of the ingredients.<h3>Key Considerations for Vacuum Evaporation&nbsp;</h3><h4>Equipment Selection</h4>Choosing the right equipment is crucial for successful vacuum evaporation. The selection depends on the sample type, volume, and specific application requirements. Here are the main types of evaporators that integrate vacuum:Rotary evaporators: Rotary evaporators, commonly referred to as "rotovaps," are widely used in laboratories for efficiently removing solvents from samples. They consist of a rotating flask, a condenser, and a vacuum system. The rotating motion increases the surface area for evaporation, and the vacuum reduces the boiling point of the solvent, making the process faster and more efficient.Large Scale Parallel Evaporators: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=338&amp;distributorItems=332&amp;search=evap">Organomation S-EVAP</a> is a specialized evaporator designed for the efficient concentration of multiple samples simultaneously. The optional vacuum manifold system to reduce the boiling point of solvents, facilitating faster evaporation at lower temperatures. This system is ideal for laboratories needing to concentrate samples in Kuderna-Danish (KD) flasks, often used in environmental testing, food and beverage analysis, and pharmaceutical research. The S-EVAP provides precise control over temperature and vacuum levels, ensuring reproducibility and safety in sample processing.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_S_EVAP_RB_Solvent_Evaporator_10_position_48376ce49a.jpg" alt="Organomation: When is Evaporation Under Vacuum Helpful?: Organomation S-EVAP-RB Solvent Evaporator - 10 position." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_S_EVAP_RB_Solvent_Evaporator_10_position_48376ce49a.jpg 120w," sizes="100vw" width="430" height="560">Vacuum ovens: Vacuum ovens are used for drying samples that are sensitive to heat or require low-temperature evaporation. They provide a controlled environment where the pressure and temperature can be precisely adjusted. Vacuum ovens are ideal for drying solid and viscous samples, as well as for performing vacuum distillations.Centrifugal evaporators: Centrifugal evaporators use a combination of vacuum, heat, and centrifugal force to evaporate solvents. They are particularly useful for high-throughput applications where multiple samples need to be processed simultaneously. These systems are commonly used in drug discovery and biochemical research.<blockquote>Discover: <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/when-nitrogen-blowdown-is-preferable-over-centrifugal-evaporation">When Nitrogen Blowdown is Preferable Over Centrifugal Evaporation</a></blockquote>Falling film evaporators: Falling film evaporators are used for continuous evaporation processes, where the liquid flows down a heated surface in a thin film. The vacuum system reduces the boiling point, and the thin film facilitates rapid solvent evaporation. These evaporators are used in large-scale industrial applications, such as in the food and beverage industry.Freeze dryers: Freeze dryers, or lyophilizers, integrate vacuum to sublimate frozen solvents directly from the solid to the gas phase. This technique is used for drying thermally sensitive materials, such as biological samples and pharmaceuticals, without damaging their structure or activity.<blockquote>Discover: <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/how-does-nitrogen-blow-down-compare-to-lyophilization">How Nitrogen Blow Down Compares to Lyophilization</a></blockquote>Spray dryers: Spray dryers use a vacuum system in combination with a spray mechanism to evaporate solvents from liquid samples. The liquid is atomized into fine droplets, which are then exposed to a heated gas stream under vacuum, causing rapid solvent evaporation. This method is used for producing powders and granules from liquid solutions.<h4>Solvent Properties</h4>Understanding the properties of the solvents being used is essential. Different solvents behave differently under vacuum, and their boiling points, vapor pressures, and potential for forming azeotropes must be considered.Vacuum evaporators excel in processing samples with naturally high boiling points, such as dimethyl sulfoxide (DMSO), N,N-dimethylformamide (DMF), and water. The reduced pressure lowers the boiling points, making the evaporation process more efficient and less thermally stressful for sensitive samples.Understanding how solvents behave under reduced pressure, including potential azeotrope formation, is critical for effective evaporation.<h4>Process Control&nbsp;</h4>Monitoring and controlling temperature and pressure are vital for optimizing the evaporation process. Precise control ensures efficient solvent removal while protecting the sample from degradation.<h4>Safety Precautions</h4>Proper handling of volatile and hazardous solvents is necessary to prevent accidents. This includes using appropriate containment, ventilation, and personal protective equipment.Evaporation under vacuum is a powerful and versatile technique with numerous advantages over traditional evaporation methods. It offers enhanced efficiency, lower operating temperatures, and improved safety, making it invaluable in both laboratory and industrial settings. As technology advances and new applications arise, the role of vacuum evaporation will continue to expand, driving innovation and improving outcomes across various scientific and industrial fields.<blockquote>To find out the best evaporation method for your needs, start a conversation with our experts at <a href="mailto:sales@organomation.com">sales@organomation.com</a>, or use our handy <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/evaporation-method-recommendation-tool">evaporation method recommendation tool</a>.</blockquote>

When is Evaporation Under Vacuum Helpful?

Hey everyone! Welcome to the second post in the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/472">GC Orbitrap</a> Guru Series. I’m super excited to share more stories about the amazing scientists and analysts behind the tech. Now in its 10th year, GC Orbitrap has made some pretty powerful impacts over that decade of discovery and I’d like to share them with you in this blog series!In the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/5332">first blog</a>, we chatted with <a target="_blank" rel="noopener noreferrer" href="https://www.wur.nl/en/persons/kerstin-kratschmer.htm">Dr. Kerstin Krätschmer</a> from <a target="_blank" rel="noopener noreferrer" href="https://www.wur.nl/en/research-results/research-institutes/food-safety-research.htm">WFSR</a> about POPs analysis and her dream of visiting Vancouver again. This time, we’re heading West to the USA, specifically <a target="_blank" rel="noopener noreferrer" href="https://www.columbia.edu/">Columbia University,</a> where I had an awesome chat with Brooklynn McNeil about GC Orbitrap and exposomics Enjoy!<div><blockquote><ul><li>Name:&nbsp;Brooklynn McNeil</li><li>Organization:&nbsp;Columbia University, Mailman School of Public Health</li><li>Job title:&nbsp;Staff Associate, Irving Institute of Clinical and Translational Research, Biomarkers Core Laboratory</li><li>Top Applications: Exposomics, Persistent organic pollutants, Emerging contaminants</li><li>Years with GC Orbitrap:&nbsp;4</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_GC_Orbitrap_Guru_Series_2_Brooklynn_Mc_Neil_4b57312077.jpg" alt="Thermo Fisher Scientific: GC Orbitrap Guru Series #2: Brooklynn McNeil" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_GC_Orbitrap_Guru_Series_2_Brooklynn_Mc_Neil_4b57312077.jpg 234w," sizes="100vw" width="1024" height="683"></blockquote>Dominic Roberts (Interviewer):&nbsp;Today, we have the pleasure of speaking with Brooklynn McNeil, a Staff Associate at Columbia University’s Mailman School of Public Health. Brooklynn, thank you for joining us. Let’s start with your background. How did you get into the field of exposomics?Brooklynn McNeil:&nbsp;Thank you for having me! My journey began with a major in Biochemistry and Molecular Biology at the University of Georgia (UGA) and a minor in Global Health. Initially, I was on the path to medical school, but I found myself more drawn to lab research. Over time, my interests shifted towards exposomics, and I’ve been dedicated to this field for the past four years. To further my expertise, I’m also pursuing a master’s degree in Environmental Health Data Science.<h3>Getting exposed to science</h3>Dom:&nbsp;That’s fascinating. Can you tell us about your first job in the scientific field?Brooklynn:&nbsp;Sure! My first paid scientific job was at the Biosceniatic Laboratory at UGA’s New Materials Institute. There, I worked on analyzing bioplastics and their decomposition in various composting conditions. It was incredibly fulfilling to contribute to solutions for the global plastic problem and it opened my eyes to the vast potential of scientific research.Dom:&nbsp;That sounds like a significant experience. How did you transition to working with GC mass spectrometry?Brooklynn:&nbsp;My first encounter with mass spectrometry was with the Thermo Scientific Exactive GC-MS. My boss at the time humorously compared it to learning to drive in a Ferrari because of its advanced capabilities. This was during my time at Mount Sinai School of Medicine, where we conducted non-target analysis of Persistent Organic Pollutants (POPs) in human samples. Having the ability to perform non-target full scan data acquisition is really powerful as it enabled us to screen for an almost unlimited number of compounds or go back to the data and re-process to look for specific target analytes.<h3>The importance of exposomics</h3>Dom:&nbsp;How do you explain exposomics to someone who isn’t familiar with the field?Brooklynn: Exposomics is the study of the exposome, which refers to the total cumulative effect of all environmental exposures we experience throughout our lives and their biological responses. This field aims to understand and measure how different environmental factors—such as chemicals, physical agents, and biological elements—affect our health. By analyzing how these exposures interact with our genetics, lifestyle, and other personal factors, exposomics offers a comprehensive view of the non-genetic causes of diseases. This approach helps us uncover the mechanisms behind disease development and can guide effective prevention and intervention strategies.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_GC_Orbitrap_Guru_Series_2_Brooklynn_Mc_Neil_2_a78dee55d9.jpg" alt="Thermo Fisher Scientific: GC Orbitrap Guru Series #2: Brooklynn McNeil" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_GC_Orbitrap_Guru_Series_2_Brooklynn_Mc_Neil_2_a78dee55d9.jpg 240w," sizes="100vw" width="1024" height="666"><h3>Supporting Exposomics with GC High Resolution MS</h3>Dom:&nbsp;What role does high-resolution mass spectrometry (HR-MS) play in your work?Brooklynn:&nbsp;GC HR-MS, particularly with Orbitrap technology, is crucial in exposomics. The sensitivity to detect low level compounds with sub-ppm mass accuracy allows us to detect and uniquely annotate thousands of chemicals in a single analysis. With compounds present at both low and high concentrations its critical to maintain performance across the full range. The second crucial part is having software and spectral libraries to process the data. For this Compound Discoverer with its statistical tools is helpful. Despite its compact size, the orbitrap is incredibly powerful. However, as a daily user, I do wish some tasks, like performing column installation and leak checks, were a bit easier.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_GC_Orbitrap_Guru_Series_2_Brooklynn_Mc_Neil_3_5931ad44a2.jpg" alt="Thermo Fisher Scientific: GC Orbitrap Guru Series #2: Brooklynn McNeil" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_GC_Orbitrap_Guru_Series_2_Brooklynn_Mc_Neil_3_5931ad44a2.jpg 234w," sizes="100vw" width="1024" height="683"><h3>It’s not all work</h3>Dom:&nbsp;That makes a lot of sense. Can you share a memorable moment from your career so far?Brooklynn:&nbsp;One of the highlights was attending the European Human Exposomics Network meeting in Brussels. The city was beautiful and left a lasting impression on me. I’d love to revisit it as a tourist, especially in the summer when it’s hopefully less rainy.Dom:&nbsp;That sounds wonderful! Lastly, what advice would you give to someone interested in pursuing a career in exposomics?Brooklynn:&nbsp;I would encourage them to explore this field because it’s constantly evolving and full of exciting discoveries. Understanding how our environment affects our health is incredibly important, and there are many opportunities to make a significant impact.Dom:&nbsp;Thank you, Brooklynn, for sharing your insights and experiences with us. It’s been a pleasure talking with you.Brooklynn:&nbsp;Thank you! It’s been great sharing my journey.I was thrilled to have had the opportunity to chat with Brooklyn for my second GC Orbitrap Guru blog. &nbsp;I’m on the lookout for more GC Orbitrap enthusiasts, so if you have a story to tell or just want to share your experiences, please get in touch! You can reach me at&nbsp;<a href="mailto:dominic.roberts@thermofisher.com">dominic.roberts@thermofisher.com</a>. I’d love to hear from you! Need to know more? Please take a look at the&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home//industrial/mass-spectrometry/gas-chromatography-mass-spectrometry-gc-ms/gc-ms-systems/high-resolution-accurate-mass-gc-ms.html">Thermo Scientific Orbitrap Exploris GC</a><blockquote>Visit us on <a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a> #GCOrbitrapGuru #gcms #DecadeofDiscovery #Exposomics</blockquote><blockquote>Dominic RobertsDominic Roberts has been closely involved with the Thermo Scientific GC Orbitrap MS since its launch in 2015. He started at Thermo Fisher Scientific as a Senior Applications Specialist for the product and is currently the GC Orbitrap MS Product Marketing Manager. Dominic is an experienced analytical chemist and mass spectrometrist with more than 20 years of experience using state-of-the-art analytical systems. He has worked in both a regulatory and industrial environment with GC–MS and LC–MS systems to investigate a variety of chemicals in food, biological, and environmental samples.</blockquote></div>

GC Orbitrap Guru Series #2: Brooklynn McNeil

The study aimed to develop a reliable GC–MS/MS method for multiresidue pesticide analysis in mealworm (Tenebrio molitor) larvae, which are known for their complex composition and high lipid content. The standard QuEChERS-based method was unsuitable for this matrix, so the authors optimized the extraction protocol by using 0.1% formic acid in acetonitrile and PSA-based cleanup to minimize matrix effects and improve analyte recovery.The final method enabled the detection and quantitation of 247 pesticides with high accuracy and low detection limits. Its application to field samples revealed triadimenol uptake from feed, indicating the method's practical utility. This approach provides a valuable tool for pesticide monitoring in edible insects for regulatory and industry purposes.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330">GC–MS/MS–based multiresidue pesticide analysis in mealworm (Tenebrio molitor) larvae: Optimization of standard QuEChERS-based method to minimize matrix effects</a></h4>Hyun Ho Noh, Chang Jo Kim, So-Hee Kim, Hye-Ran Eun, Yongho Shin, Won Tae Jeong&nbsp;Food Chemistry: X, Volume 27, April 2025, 102386<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.fochx.2025.102386">https://doi.org/10.1016/j.fochx.2025.102386</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.The consumption of animal products has increased with the increasing global population, and the demand for consumable crop–derived calories and proteins is expected to increase 2.1-fold by 2050 (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0050">Hunter et al., 2017</a>). Given the need to promote sustainable food production, considerable attention has been drawn to decreasing the reliance of pest management on chemicals (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0110">Rockstrom et al., 2017</a>). However, the fact that wheat, corn, and cotton losses due to pests reached 38.3&nbsp;% in 1964–2003 (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0085">Poppe et al., 2003</a>) indicates the importance of pesticides for preventing crop damage by fungi, insects, mites, weeds, and other pests and thus securing stable food production (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0015">Burger et al., 2008</a>). Additionally, climate and weather changes directly and indirectly affect crop production and pest reproduction, distribution, and migration. Thus, food production should be increased while reducing the use of chemicals (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0090">Porter et al., 1991</a>).Insects are rich in proteins (40&nbsp;%–70&nbsp;%), minerals, and vitamins, thus holding promise as alternative protein sources for the food industry (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0040">Gravel &amp; Doyen, 2020</a>). Over 2000 insect species are consumed in various countries, including those in Asia and Europe (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0135">van Huis, 2020</a>). The production of edible insects is more environmentally friendly and sustainable than livestock farming (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0030">FAO, 2013</a>), and the growth of the domestic and international insect market is expected to continue. Edible insects include members of the orders Lepidoptera, Coleoptera, Orthoptera, and Hymenoptera (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0145">Yoo et al., 2013</a>). In particular, the larvae of the mealworm beetle (Tenebrio molitor) have a protein content of 46.44&nbsp;% and are nutritionally rich alternative food sources (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0105">Ravzanaadii et al., 2012</a>). However, edible insects may contain harmful substances, such as microorganisms, chemicals, and parasites, with numerous studies reporting the detection of pesticides, including organophosphates and benzoquinones (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0010">Belluco et al., 2013</a>).Pesticides are toxic to humans and the environment and can harm the immune, reproductive, and nervous systems. In response to the concerns related to pesticide residues in agricultural products and human exposure (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0020">Damalas &amp; Eleftherohorinos, 2011</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0065">Lushchak et al., 2018</a>), the European Union (EU) has established 464 maximum residue limits to regulate pesticides in terrestrial invertebrates, including insects (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0025">EU, 2024</a>). In South Korea, the Rural Development Administration and Ministry of Food and Drug Safety set safety guidelines and residue limits for various crops, while the National Agricultural Products Quality Management Service and Ministry of Food and Drug Safety conduct safety investigations on harmful substances, including pesticide residues, in domestically produced and distributed agricultural products to ensure safe food production. However, no residue limits have been established for pesticides in edible insects in South Korea, which indicates the need to establish and monitor pesticide residue analysis methods, particularly for applying uniform PLS (positive list system) standards and future maximum residue limits.Owing to the high protein and fat contents of mealworm larvae, the analysis of pesticide residues therein requires pretreatment to prevent contamination (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0105">Ravzanaadii et al., 2012</a>), as exemplified by protein and fat removal based on the QuEChERS method and n-hexane treatment (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0045">Houbraken et al., 2016</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0100">Ramluckan et al., 2014</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0115">Shin et al., 2020</a>). Acetonitrile/hexane partitioning is necessary to improve the recovery rates of high-distribution-coefficient pesticides during gas chromatography-tandem mass spectrometry (GC–MS/MS) analysis (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0120">Shin et al., 2018</a>). Additionally, adsorbents commonly employed in the QuEChERS method, such as primary secondary amine (PSA), C18, Z-Sep, Z-Sep+, and HLB (hydrophilic lipophilic balance), should be used to remove potential interferents from the extract. Herein, we aimed to (i) develop a method for the simultaneous analysis of multiple pesticides and related metabolites in mealworm larvae using a GC–MS/MS–based modified QuEChERS approach and (ii) validate the effectiveness of this method by applying it to real mealworm larvae. The method improves routine residual pesticide analysis procedures to provide a breakthrough the analysis of high-protein and high-fat samples.<h4>2. Materials and methods</h4><h5>2.4. Instrumentation</h5>Pesticide analysis was performed using an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=7000C+triple-quadrupole">7000C triple-quadrupole mass spectrometer </a>coupled with an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=7890B+gas+chromatograph+">7890B gas chromatograph </a>(Santa Clara, CA, USA). The carrier gas (helium) was supplied at a flow rate of 1 mL/min. Samples were injected in the solvent vent mode, and the vent flow rate was held at 50 mL/min for the first 1.5 min, decreased to 25 mL/min, and maintained (5 psi) for 0.3 min. The target analytes were separated on an HP-5 ms column (30 m × 250 μm × 0.25 μm). The oven temperature was held at 50 °C for 3 min, increased to 185 °C at 30 °C/min, 250 °C at 5 °C/min, and 300 °C at 10 °C/min, and held for 7 min. The source and transfer line temperatures were set to 250 and 290 °C, respectively. Electron ionization was performed at 70 eV, and all pesticides were analyzed in the dynamic multiple reaction monitoring mode.<h4>3. Result and discussion</h4><h5>3.1.2. Partitioning efficiency</h5>Mealworm larvae have a fat content of 21.9&nbsp;wt% (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0055">Imathiu, 2020</a>) and should therefore be defatted prior to analysis to remove interferents and prevent the contamination of the GC–MS/MS instrument. Therefore, n-hexane, a nonpolar solvent effective for fat removal, was employed (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0100">Ramluckan et al., 2014</a>). Additionally, n-hexane (partition coefficient&nbsp;=&nbsp;3.90) has a higher affinity than acetonitrile (partition coefficient&nbsp;=&nbsp;−0.34) and can therefore extract nonpolar pesticides that may remain in the extraction solvent. Using n-hexane-saturated acetonitrile, we examined the effect of partitioning frequency on recovery rates (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#t0010">Table 2</a>). Each additional partitioning led to a higher pesticide recovery, with four partitions yielding a 22 percentage point increase in recovery (84.6&nbsp;%) compared with a single partition. At this level, 209 pesticides demonstrated acceptable recovery rates (70&nbsp;%–120&nbsp;%) and precisions (RSD&nbsp;≤&nbsp;20&nbsp;%). Thiocarbamate and organochlorine pesticides exhibited low recovery rates, probably because of their high partition coefficients (log P&nbsp;=&nbsp;4.1–6.9) due to their low polarities, and were therefore retained in the n-hexane phase (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0070">Mathieu et al., 2015</a>; <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#bb0075">Mdeni et al., 2022</a>). However, the recovery rates of these pesticides increased with the increasing partitioning frequency (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#f0005">Fig. 1</a>). Therefore, partitioning with n-hexane-saturated acetonitrile was concluded to be essential for improving the recovery of pesticides with high partition coefficients, and the optimal number of partitions was identified as four.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Food_Chemistry_X_Volume_27_April_2025_102386_Fig_1_Recovery_rates_bars_and_partition_coefficients_log_P_triangles_of_10_representative_pesticides_2_79886fbb41.jpg" alt="Food Chemistry: X, Volume 27, April 2025, 102386: Fig. 1. Recovery rates (bars) and partition coefficients (log P, triangles) of 10 representative pesticides showing a strong dependence of recovery (>25 %) on the number of partitionings (N = 1, 2, 3, and 4). Error bars are the standard deviations of the recovery rates (n = 4)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Food_Chemistry_X_Volume_27_April_2025_102386_Fig_1_Recovery_rates_bars_and_partition_coefficients_log_P_triangles_of_10_representative_pesticides_2_79886fbb41.jpg 245w," sizes="100vw" width="1600" height="957"><h5>3.3. Real sample analysis</h5>Among the 24 samples collected from domestic mealworm larva farms, 11 contained the triazole fungicide triadimenol at concentrations of 14–996&nbsp;μg/kg (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S2590157525002330#f0020">Fig. 4</a>) and were therefore noncompliant with the EU residue limit for terrestrial invertebrates (10&nbsp;μg/kg). Considering that the triadimenol residue limit for wheat, the primary ingredient of bran fed to mealworms, is 100&nbsp;μg/kg, pesticide absorption probably occurred through bran consumption. Thus, the established method for the multiresidue analysis of 247 pesticides in mealworm larvae was concluded to be applicable in field settings and enable both quantitative and qualitative analyses.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Food_Chemistry_X_Volume_27_April_2025_102386_Fig_4_Chromatograms_of_triadimenol_obtained_for_acetonitrile_control_pure_standard_2_c9e6bb0fed.jpg" alt="Food Chemistry: X, Volume 27, April 2025, 102386: Fig. 4. Chromatograms of triadimenol obtained for acetonitrile, control, pure standard (10 µg/kg), matrix-matched standard (10 µg/kg), and mealworm samples (6, 8, 15, 18, 20, 21, 22, 26, 28, 30, and 31)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Food_Chemistry_X_Volume_27_April_2025_102386_Fig_4_Chromatograms_of_triadimenol_obtained_for_acetonitrile_control_pure_standard_2_c9e6bb0fed.jpg 187w," sizes="100vw" width="1436" height="1200"><h4>4. Conclusions</h4>A GC–MS/MS–based multiresidue method for the detection and quantitation of 247 pesticides in mealworm larvae was developed, optimizing the standard QuEChERS procedure to account for matrix complexity and high fat content, and validated. Pesticide recovery rates were maximized by combining 0.1&nbsp;% formic acid in acetonitrile (extraction solvent) with the original QuEChERS packet. Further cleanup (PSA d-SPE) effectively removed matrix interferences without significant analyte loss, enhancing detection accuracy. According to the results of validation tests, the developed method exhibited high linearities, acceptable recovery rates, and low detection limits for most analytes and was therefore concluded to be robust and suitable for both quantitative and qualitative analyses. The analysis of 24 field samples revealed detectable levels of triadimenol, suggesting its potential uptake from bran feed. Thus, this validated approach was concluded to be suitable for application in regulatory and industrial settings, offering a reliable tool for monitoring pesticide residues in mealworm larvae and similar edible insect matrices.

GC–MS/MS–based multiresidue pesticide analysis in mealworm (Tenebrio molitor) larvae: Optimization of standard QuEChERS-based method to minimize matrix effects

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Peak Scientific

The first in this series, brought to you by our GC gas product expert, Dr. Ed Connor, will cover Precision SL&#39;s industry-leading small size and how it can benefit your lab&#39;s workflow and will take place on Wednesday, 28th of July at 09.30 (GMT+1).
The webinar will be followed by a live Q &amp; A session for any questions you may have about Precision SL or lab gas generators in general.
<blockquote>
Presenter: Dr Ed. Connor (Product Manager, Peak Scientific)
</blockquote>
<blockquote>
joined Peak Scientific in February 2013 as a GC product specialist and now functions as a Product Manager. He has been working on a number of collaborative projects with Peak customers and the major instrument manufacturers worldwide. The main focus of these collaborations has been to look at conversion from helium to hydrogen or nitrogen carrier gas for GC applications but he has also worked on ELSD nitrogen gas solutions and nitrogen generators for LC-MS instruments. Prior to joining Peak, Ed completed his Dr.Sc. at ETH Zurich in 2007 using GC-MS to look at herbivore induced plant volatiles and their interaction with beneficial insects. He then joined the University of Zurich where his work focussed primarily on floral volatile analysis using a variety of volatile collection methods, GC-MS and GC-FID.
</blockquote>

Peak Scientific: Streamline your GC-FID analysis with Precision SL

Streamline your GC-FID analysis with Precision SL

Bulk gas supply in the form of liquid nitrogen dewars and cylinders present laboratories with safety risks stemming from the frequent need to handle and manage gas supplies. Laboratory staff are at risk of injury every time they need to move a gas cylinder and a leak from bulk storage can result in the development of a potentially deadly atmosphere.
Flammable gases such as hydrogen present additional risks of fire or explosion, which need to be addressed through safe gas handling, storage and detection in the laboratory, increasing the cost of their use.
<h3>Attend this webinar to learn about:</h3>
<ul>
<li>General gas cylinder safety tips</li>
<li>Risks associated with bulk gas supply</li>
<li>The risks of using nitrogen and hydrogen in the laboratory</li>
<li>Benefits of using a gas generator to supply nitrogen and/or hydrogen</li>
</ul>
<blockquote>
Presenter: Dr. Ed Connor (Product Manager, PEAK Scientific)
</blockquote>

Unsplash/Julia Lobkova: Gas Safety in Your Laboratory

Gas Safety in Your Laboratory

There is a general perception that gas chromatography (GC) and the various forms of detection that are used with this technique have developed to the point where it is now a “mature” technology, but GC practitioners know that there are many new challenges to face and that new solutions are required to overcome longstanding issues.
This virtual symposium, organized by the Chromatographic Society (ChromSoc) and LCGC, will focus on areas of GC where the sample complexity, the requirements for highly accurate measurements, the sensitivity requirements imposed by regulators, and the need to push scientific discovery force GC users to look with fresh eyes on this supposedly “mature” technique. The highly respected international speakers will bring a fresh perspective on almost every aspect of GC in the vapour phase and the virtual symposium will maintain the high reputation that this bi-annual meeting has established over many years.
<h3>Key Learning Objectives:</h3>
<ul>
<li>Modern approaches to achieving ultratrace detection limits in GC and GC–MS are revealed</li>
<li>The use of GC and GCxGC with high-resolution MS for complex sample screening will be discussed</li>
<li>Learn about advanced techniques for sample preparation and enrichment for qualitative and quantitative analysis</li>
</ul>
<h3>Who Should Attend:</h3>
Anyone working with GC who wants to understand the very latest approaches to achieving ultratrace analyte quantitation, sample preparation, and enrichment for complex matrices and reducing error in quantitative GC analysis.
<h3>Agenda:</h3>
<ul>
<li>12pm BST = 7am EDT Symposium Introduction (Tony Taylor, Arch Sciences Group, UK)
</li>
<li>12:30pm BST = 7:30am EDT High Resolution GC–MS and GC×GC–MS with Advanced Data Processing for Investigative Compositional Analysis (Hans-Gerd Janssen, Unilever and Wageningen University, The Netherlands)
</li>
</ul>
<h4>Technology Session 1</h4>
<ul>
<li>1:10pm BST = 8:10am EDT Hydrogen Carrier Gas for Fast GC: Choosing the right setup for your GC (Ed Connor, Product Manager, PEAK Scientific)
</li>
<li>1:25pm BST = 8:25am EDT Derivatization and Traceable Quantification—A Match Made in Hell? (Chris Hopley, LGC’s National Measurement Laboratory, UK)
</li>
</ul>
<h4>Technology Session 2</h4>
<ul>
<li>2:05pm BST = 9:05am EDT Low-Pressure Gas Chromatography (LPGC)–The Fast Way to Your Pesticide Analysis (Dr. Jana Hepner, Applications Scientist, Restek)
</li>
<li>2.20pm BST = 9:20am EDT Meeting the Analytical Challenges of Environmental Monitoring for the Water Framework Directive: Quantifying a Drop (or Two) in the Ocean (John Quick, ALS Environmental, UK)
</li>
</ul>
<h4>Technology Session 3</h4>
<ul>
<li>3pm BST = 10am EDT VICI Fast Temperature Programmer Methods and Applications (Dale Ashworth, Product Manager Analytical Systems, VICI)
</li>
<li>3:15pm BST = 10:15am EDT Is the E&amp;L Community Ready to Move Away from Conventional Large Volume Liquid–Liquid Extraction and Solvent Evaporation? (Mike Hodgson, Baxter, UK)
</li>
</ul>
<h4>Technology Session 4</h4>
<ul>
<li>3:55pm BST = 10:55am EDT Raise the Bar of Trace Analysis: Simultaneous high quality target and non-target data are within reach (Liz Humston-Fulmer, Application Chemist, LECO Corporation)
</li>
<li>4:10pm EDT = 11:10am EDT Combining Automated Green and Exhaustive Enrichment Techniques with 1D GC–TOF–MS for Untargeted Aroma Profiling of Food/Beverages and Consumer Products in QA/QC Industrial Laboratories (Tatiana Cucu, Research Institute of Chromatography)
</li>
<li>4:50pm BST = 11:50am EDT Technology Session 5
</li>
<li>5:05pm BST = 12:05pm EDT Technology Session 6
</li>
<li>5:20pm BST = 12:20pm EDT Panel Discussion
</li>
</ul>

ChromSoc: Advances in Gas Chromatography: A Virtual Symposium

Advances in Gas Chromatography: A Virtual Symposium

<a href="https://gcms.cz/products?search=pegasus&amp;manufacturerItems=24&amp;instrumentationItems=3">LECO&#39;s Pegasus®</a> line is designed to take full advantage of the speed of TOFMS analyses without sacrificing the sensitivity you need, and our<a href="https://gcms.cz/library?search=+stayclean&amp;mainauthorItems=24"> StayClean®</a> Ion Source means you never have to slow down to clean out your engine.
The advantages of helium as a carrier gas for mass spectrometers have long been known, but it is a limited natural resource with varied supplies and expenses. On the other hand, hydrogen gas generators can be installed in any lab for a constant supply and, conveniently, increased chromatographic speeds.
Join LECO&#39;s panel of experts for a one-day forum to discuss how to overcome the challenges of switching from helium to hydrogen, the analytical and business impacts of adding hydrogen generators to your lab, and how the resulting mass spectral profiles compare between helium and hydrogen gases.
<h3>Forum Talks</h3>
<h4>Fast GC/Hydrogen Method Transfer Overview &amp; Application Examples</h4>
Helium is a limited natural resource with huge variations in both supply and expense. At the same time, the advantages of hydrogen to achieve increased chromatographic throughput in GC applications is attractive. The transferral of methods to hydrogen carrier gas can be problematic due to limitations and challenges associated with some types of mass spectrometry technology used. In particular, the mass spectral quality and fragmentation, in comparison with that obtained using helium, as well system sensitivity and also, system robustness and acquisition rate are important factors which can differ and negatively affect results. In this study we have investigated the use of a particular type of GC-TOF-MS technology in regards to overcoming these issues. The method transfer approach, technology benefits, and application examples are presented.
<blockquote>
Presenter: Nick Jones an David Benanou
</blockquote>
<h4>Flow Modulated Fast Comprehensive Two-Dimensional Gas Chromatography Combined With Time-of-Flight Mass Spectrometry: A Comparison Between the use of Helium and Hydrogen as Carrier Gas</h4>
The present research is focused on the comparison between the use of hydrogen and helium carrier gases, within the context of flow-modulation fast comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. All experiments were carried out by using the following column set: low polarity with dimensions 10 m × 0.25 mm ID × 0.25 µm df and medium polarity with dimensions 2 m × 0.10 mm ID × 0.10 µm df. Fundamental gas chromatography parameters (efficiency, resolution) were measured under different experimental conditions, using the two carrier gases. Efficiency was measured in both the first (using C12 alkane) and second (using naphthalene) dimensions; after defining the optimum carrier gas conditions, a sample of diesel was analyzed, with the overall separation evaluated to make final conclusions on the analytical performances. Finally, a comparison was made between mass spectral profiles obtained analyzing fatty acid methyl esters and pesticides.
<blockquote>
Presenter: Peter Q. Tranchida and Luigi Mondello (University of Messina, Messina, Italy)
</blockquote>
<h4>Switch to Fast GC Easily - Theory and Practice</h4>
There a number of ways that the analysis time can be reduced. It all depends on how well the components are separated in the present application. Most easy is to trade in some resolution for speed using higher gas velocities or using a shorter column. If the exact separation must be maintained, a choice has to be made between using hydrogen as carrier gas, or use a smaller ID capillary column (or a combination). What is important is that in the new method, the same chromatogram (and peak elution order) must be obtained. Using the EZGC method translator, you can simply calculate the oven program you need for that. Also, in the ProEZGC chromatogram modeler, you can see the impact of any changed parameter, just using your laptop.
<blockquote>
Presenter: Jaap de Zeeuw (Restek)
</blockquote>
<h4>Advantages of Hydrogen Generators: Usage, Costs, and Safety Made Easy</h4>
Analytical laboratories use a variety of analytical techniques as part of their research and development and quality control of products. Many of these processes require high purity gases, many of which can be produced by gas generators. For a number of reasons, including safety, cost, convenience, and analytical throughput, more and more labs are abandoning hydrogen cylinders in favor of hydrogen gas generators to supply the gases they require for their analyses. During this session, Jean-Marie Casanova will cover analytical and business impacts about implementing Hydrogen gas generators in your lab.
<blockquote>
Presenter: Jean-Marie Casanova (Sales Director, F-DGSi)
</blockquote>

LECO: Designed for Speed: A Fast-GC Forum

Designed for Speed: A Fast-GC Forum

The second in this series, brought to you by our GC gas product expert, Dr. Ed Connor, will review Precision SL as a safe source of hydrogen and will cover all safety aspects of the Precision SL in your lab.
The webinar will be followed by a live Q&amp;A session for any questions you may have about Precision SL or lab gas generators in general.
<blockquote>
Presenter: Dr. Ed Connor (Product Manager, Peak Scientific)
</blockquote>

Precision SL for GC-FID (POSTPONED)

Join us for a series of webinars on the latest technology for GC-FID gas supply, the Precision SL hydrogen gas generator from PEAK Scientific.

Precision SL for GC-FID

Helium shortages mean that laboratories will soon need a sustainable alternative to this non-renewable resource. Also, the struggle to maintain a consistent helium supply is causing a drop in productivity in many labs and the cost of helium continues to rise.
Progressing to a more sustainable laboratory is possible by switching to a multi-gas system. Switching to hydrogen, for example, protects laboratories against future helium shortages and is more sustainable because high-purity hydrogen can be generated from water. Hydrogen offers faster chromatographic separations, shorter thermal desorption methods and lower-temperature separations than helium, drastically increasing laboratory throughput, extending consumables’ lifetimes and extending maintenance intervals. Hydrogen also produces the same high-quality data as helium but at a greatly reduced cost.
<h3>By attending the presentation you’ll learn about:</h3>
<ul>
<li>The current situation with the global supply of helium</li>
<li>The benefits of using hydrogen as a carrier gas</li>
<li>Configuring thermal desorption–gas chromatography–mass spectrometry analytical instrumentation to work safely with hydrogen as a carrier gas as well as with helium and nitrogen</li>
<li>The pros and cons of different hydrogen sources (bulk supply vs gas generator)</li>
<li>Common pitfalls when switching carrier gas and how to avoid them</li>
</ul>
<blockquote>
Presenter: Ed Connor
</blockquote>
<blockquote>
joined PEAK Scientific in February 2013 as a GC product specialist and now functions as a Product Manager. He has been working on a number of collaborative projects with PEAK customers and the major LC-MS and GC instrument manufacturers worldwide. The main focus of these collaborations has been to look at conversion from helium to hydrogen or nitrogen carrier gas for GC applications but he has also worked on ELSD nitrogen gas solutions and nitrogen generators for LC-MS instruments.
</blockquote>
<blockquote>
Presenter: Jessica Berger
</blockquote>
<blockquote>
graduated from the University of Glamorgan (now University of South Wales) with a BSc. degree in Chemistry. She joined Markes International in 2012 as an Inside Sales Specialist, before being promoted to Product Manager for the thermal desorption business unit. In this role, Jessica is responsible for both the introduction of new thermal desorption products, as well as the management of the exiting product line.
</blockquote>

Pixabay/Andrew Martin: Moving Towards Sustainable Gas Chromatography Laboratories

Moving Towards Sustainable Gas Chromatography Laboratories

Don’t miss this opportunity to attend the Virtual Dioxins Summit.
This one-day interactive online summit offers you valuable information for keeping up-to-date on the latest dioxin trends and developments in the field.
<h5>The Agilent Virtual Dioxins Summit offers:</h5>
<ul>
<li>An exciting meeting in a virtual environment, conducive to business, scientific, and social exchange</li>
<li>Access to both the fundamental and practical aspects of dioxin separation science, with the main focus on new and highly relevant trends emerging in this field for improvingd ioxin analysis</li>
<li>The opportunity to focus on the newest scientific trends and professional developments in dioxin analysis.</li>
</ul>
<h5>During the summit you will have the opportunity to:</h5>
<ul>
<li>Listen to top leaders and application experts from the comfort of your home or office</li>
<li>Ask each speaker questions in the real-time Q&amp;A session following each broadcast</li>
<li>Visit our exhibition booths virtually through the online platform</li>
<li>Virtually meet, chat, and exchange ideas with all participants, as well as with Agilent experts</li>
</ul>
We are pleased to share that the first talks and speakers have been confirmed for the Agilent Virtual Dioxins Summit.
More talks from top leaders will be confirmed soon- stay tuned.
This is a meeting for you – feel free to get involved, ask questions, make suggestions and be a part of the Agilent Dioxin Community.
Register today and stay up-to-date on the program.
We look forward to “seeing” you at this virtual event.
<h3>Program</h3>
<h5>09:55 a.m. – 10:00 a.m. CEST Welcome and introduction</h5>
<ul>
<li>Juan Aybar (EMEA Business Team Manager GC/GCMS, Agilent Technologies)</li>
</ul>
<h5>10:00 a.m. – 10:30 a.m. CEST Introducing the Agilent Dioxin Workflow Kit for the Determination of PCDD and PCDF in Foods and Feeds</h5>
<ul>
<li>Jörg Riener (GC and GC/MS Product Specialist, Agilent Technologies)</li>
</ul>
<h5>10:30 a.m. – 11:00 a.m. CEST Implementation and Evaluation of Hydrogen as a GC carrier gas for the rapid analysis of PCDD/Fs using the novel High Efficiency Ion Source of the 7010 GC/QQQ</h5>
<ul>
<li>Frank Neugebauer (Senior Scientist, Head of Special Parameter Unit, Eurofins GfA Lab Service, Hamburg, Germany)</li>
</ul>
<h5>11:00 a.m. – 11:30 a.m. CEST Helium – Global supply and viable alternatives for GC-MS analysis</h5>
<ul>
<li>Ed Connor (Product Manager, PEAK Scientific)</li>
</ul>
<h5>11:30 a.m. – 12:00 p.m. CEST Biomagnification and Temporal Trends of Legacy, New and Emerging POPs and Transformation Products in Baltic Sea Biota</h5>
<ul>
<li>Peter Haglund (Professor of Environmental Analytical Chemistry, Umeå University)</li>
</ul>
<h5>12:00 p.m. – 12:30 p.m. CEST Recent advances in the routine analysis of Dioxins in food and environmental samples</h5>
<ul>
<li>Robert (Bob) Symons (Regional Technical Manager, Eurofins Environment Testing Australia)</li>
</ul>
<h5>12:30 p.m. – 01:30 p.m. CEST Break</h5>
<h5>01:30 p.m. – 02:00 p.m. CEST Introducing LCTech sample preparation workflow for optimal Dioxin sample handling from extraction to injection</h5>
<ul>
<li>Angelika Köpf (LCTech GmbH)</li>
</ul>
<h5>02:00 p.m. – 02:30 a.m. CEST Dioxin and furans analysis in GC-QTOF according with EPA Method 1613B/1994</h5>
<ul>
<li>Nicole Canfora (LABORATORI CHIMICI “STANTE” SRL)</li>
</ul>
<h5>02:30 a.m. – 03:00 p.m. CEST Agilent GC-QTOF workflow for EPA Method 1613B</h5>
<ul>
<li>Marica Beggio (Product Specialist GC-GC/MS, Agilent Technologies)</li>
</ul>
<h5>03:00 p.m. – 03:30 p.m. CEST Development of an Alternate Testing Protocol (ATP) to EPA1613B for Analysis of Dioxins in Wastewater using EI-GC/MS/MS</h5>
<ul>
<li>Tarun Anumol (Director Global Environment &amp; Food Applied Markets, Agilent Technologies)</li>
</ul>
<h5>03:30 p.m. CEST Thank you and Good Bye</h5>
<ul>
<li>Lorenzo Gaddoni (EMEA Marketing Program Manager, Agilent Technologies)</li>
</ul>

Agilent Technologies: Agilent Virtual Dioxins Summit

Agilent Virtual Dioxins Summit

This one-day interactive online summit offers you valuable information for keeping up-to-date on the latest dioxin trends and developments in the field.

Recent technological advancements have greatly expanded the options for high-quality mass spectrometry equipment. With significant progress in GC-MS, LC-MS, and gas generators, critical analyses can now be conducted with enhanced effectiveness and efficiency.
Join our technical webinar to gain a comprehensive overview of cutting-edge MS equipment and the latest innovations in utilizing hydrogen as a carrier gas. Discover the advancements, including Agilent&#39;s quadrupole time-of-flight LC-MS and PEAK Scientific&#39;s nitrogen gas generator, designed to optimize competitiveness and productivity in your analytical workflows.
<h5>Attend this webinar to:</h5>
<ul>
<li>Learn about why there is a huge drive to switch to hydrogen as a carrier gas for GC</li>
<li>Discover how to achieve time-saving efficiencies and meet future challenges with instrument intelligence using the latest quadrupole time-of-flight LC-MS</li>
<li>Understand how a gas generator can save you time and money as well as improve your lab’s sustainability</li>
</ul>
<h3>1. Novel Mass Spectrometry Technologies Expand Future of Biomarker Discovery Research</h3>
<ul>
<li>Diane Turner (Director and Senior Consultant, Anthias Consulting Ltd)</li>
</ul>
Gas chromatography - mass spectrometry (GC-MS) instruments are used for a wide variety of critical analyses and presents a topic of growing importance as the industry collectively moves away from helium as a carrier gas due to availability and pricing to suitable alternatives such as hydrogen.
In this webinar, Dr. Diane Turner from Anthias Consulting Ltd will focus on the innovations around using hydrogen as a carrier gas and explore the associated benefits as well as address the challenges involved.
<h5>In his talk, she will cover:</h5>
<ul>
<li>Why there is a huge drive to switch to hydrogen as a carrier gas for GC</li>
<li>The associated benefits and negatives of using hydrogen</li>
<li>A ‘to do’ list of parameters to re-optimize when switching to hydrogen</li>
</ul>
<h3>2. Be Ready for Future Challenges With an Intelligent LC-MS Solution</h3>
<ul>
<li>Christian Klein (Product Manager LC/Q-TOF and IM-QTOF, Agilent Technologies)</li>
</ul>
Many labs are faced with an ever-increasing sample load, while instrumentation and resources remain at a steady level. As a consequence, instrument throughput and uptime are critical factors to maintain competitiveness and productivity.
In this webinar, Dr. Christian Klein will show how you can meet these challenges with the newest time-of-flight LC-MS from Agilent. See examples of complete workflows demonstrating performance, robustness and throughput for food safety screening applications.
<h5>In his talk, he will cover:</h5>
<ul>
<li>Time-saving efficiencies and meeting future challenges with instrument intelligence</li>
<li>How to implement end-to-end workflows for food safety to produce meaningful results</li>
<li>How to identify and quickly assess compounds in question</li>
</ul>
<h3>3. How Can a Gas Generator Benefit Your Lab?</h3>
<ul>
<li>Petra Gierga (Product Manager, PEAK Scientific)</li>
</ul>
Labs face challenges every day and lab gas should not be one of these problems. On-site gas generators play a pivotal role in helping labs to streamline workflows while providing high-quality gas for LC-MS analysis.
In this webinar, Petra Gierga from PEAK Scientific will be discussing the benefits a gas generator can provide your lab over cylinders, dewars or bulk supply. Removing the need for repeated cylinder deliveries, cylinder contracts, manual handling and changing of cylinders – an in-house gas generator can reduce costs, increase productivity and improve your lab’s sustainability efforts.
<h5>In this talk, she will cover:</h5>
<ul>
<li>How a gas generator can save you time</li>
<li>The economic benefits of using a gas generator</li>
<li>The advantages a gas generator has for your labs workflows and long-term sustainability goals</li>
</ul>

Technology Networks: Breaking the Boundaries: The Latest Innovations in Mass Spectrometry

Breaking the Boundaries: The Latest Innovations in Mass Spectrometry

Technical webinar: overview of cutting-edge MS equipment and the latest innovations in utilizing H2 as a carrier gas, LC/Q-TOF or N2 gas generators.

The Latest Innovations in Mass Spectrometry

Join this webinar to explore the utility of hydrogen in chemical research, its associated risks, and a safer laboratory solution: H-Genie® Lite. This innovative, compact hydrogen generator employs unique patented cell technology to convert water into high-purity hydrogen gas, reaching pressures up to 50 bar (725 psi). As an ideal replacement for conventional hydrogen cylinders, it not only boosts lab safety but is also perfect for filling autoclaves and pressured containers.
Subsequently, we will delve into metal-catalyzed hydrogenation reactions. Heterogeneous catalysts like Pd/C are commonly employed for nitro group reductions and hydrogenation of carbon-carbon and carbon-heteroatom double bonds. These catalysts also aid in O- and N- deprotection, yielding respective alcohols or amines, and in asymmetric hydrogenation reactions.
We’ll discuss the core principles of hydrogenation, featuring both heterogeneous and homogeneous catalysts, and highlight their significance in industrial applications. H-Genie® Lite seamlessly integrates with both batch and continuous flow chemistry hydrogenation processes.
<blockquote>
Presenter: Nándor Kánya, PhD (Head of Experimental Chemistry, ThalesNano)
</blockquote>
<blockquote>
Nándor graduated from Budapest University of Technology and Economics as a Pharmaceutical Engineer in 2016, followed by a PhD degree in synthetic organic chemistry from the University of Debrecen in 2021. He joined ThalesNano in 2021 as an Application Scientist and became the leader of Experimental Chemistry in 2022.
</blockquote>
<blockquote>
Presenter: Thomas Colacot, PhD (R&amp;D Fellow and Director of Global Technology Innovation, Merck KGaA, Darmstadt, Germany)
</blockquote>
<blockquote>
Thomas J. Colacot holds a Ph.D. in chemistry and an MBA. He joined MilliporeSigma in 2018 and currently serves as an R&amp;D Fellow and Director of Global Technology Innovation in the Life Science Business division. He is an expert in organometallics and homogeneous catalysis and has a strong track record of commercializing innovative products. Colacot has published over 120 peer-reviewed articles and holds 67 international patents. He has been recognized with various awards, including a lifetime achievement award from the Chairman and CEO of Merck KGaA, Darmstadt, Germany. From 1995 to 2018, he was instrumental in establishing a successful homogeneous catalysis program at Johnson Matthey.
</blockquote>

Safe Hydrogenation in the Lab

Safe Hydrogenation in the Lab with H-Genie® Lite

Safe Hydrogenation in the Lab H-Genie® Lite

Laboratories rely on efficiency, safety, and cost-effectiveness to optimize their workflows. One of the most significant factors in achieving these goals is ensuring a reliable supply of nitrogen gas. Organomation’s latest webinar, Improving Laboratory Workflows through Nitrogen Generation, explores how nitrogen generators can revolutionize lab operations by eliminating the need for gas cylinders.<h4>The Challenge: Gas Cylinders vs. On-Site Nitrogen Generation</h4>Traditionally, many laboratories depend on nitrogen cylinders, which come with hidden costs and logistical challenges.&nbsp;These include:<ul><li>Rental Fees: The recurring costs of renting cylinders add up over time.</li><li>Refill and Delivery Charges: Market fluctuations and scheduling conflicts can delay deliveries, leading to downtime.</li><li>Safety Concerns: Handling and transporting high-pressure cylinders can pose workplace hazards.</li><li>Space Limitations: Storing multiple bulky cylinders takes up valuable lab space.</li></ul>Organomation’s David Oliva shared a real-world example of a lab located in a multi-floor building without an elevator. Employees were forced to carry heavy gas cylinders up and down staircases, creating an unnecessary safety risk. Another lab experienced a several-week delay in research due to a miscommunication in their cylinder delivery. Situations like these highlight the need for a more reliable and efficient solution.<h4>The Solution: On-Site Nitrogen Generation</h4>Nitrogen generators provide labs with a cost-effective, continuous nitrogen supply while addressing many of the pain points associated with gas cylinders.Key benefits include:<ul><li>Significant Cost Savings: Eliminates rental, refill, and delivery fees.</li><li>Operational Efficiency: Reduces workflow disruptions by ensuring an uninterrupted nitrogen supply.</li><li>Enhanced Safety &amp; Convenience: Removes the need to store and handle high-pressure cylinders.</li><li>Space Optimization: Compact generators free up valuable lab space.</li><li>Sustainability: Reduces the environmental impact associated with nitrogen gas transportation.</li></ul>To help labs assess whether a nitrogen generator is a worthwhile investment, Organomation has developed a payback calculator. Many labs find that they achieve a full return on investment within 1-2 years.<h3>Real-World Success Stories</h3>Several laboratories have already made the switch to nitrogen generators, experiencing improved efficiency and cost savings.<h4>Temple University’s McKenzie Environmental Engineering Research Group</h4>Temple University’s research group, which concentrates PFAS sample extracts for mass spectrometry, made the transition to nitrogen generation to combat rising costs associated with tank rentals, delivery, and surcharges. Their investment in the NITRO-GEN generator allowed them to meet growing sample throughput requirements without the logistical headaches of cylinder replacements. With a compact design and plug-and-play functionality, the generator seamlessly integrated into their workflow.<h4>Moyo Lab at Louisiana State University</h4>The Moyo Lab, which studies nutrient movement across habitats, relies on nitrogen evaporation to remove excess chloroform from their extraction samples. Dissatisfied with nitrogen cylinders, they opted for the NITRO-GEN+ generator to streamline their operations.Lab Manager and Assistant Professor of Biology Sydney Moyo shared his experience:"I love the NITRO-GEN+ for many reasons. First, a vital benefit is that I can move the generator around the department because it has wheels. When I used cylinders, I had difficulty moving them around the lab. Second, when the NITRO-GEN+ is not in use, I can safely store it in a corner in my lab because it only takes up a little space. Third, the NITRO-GEN+ is also very quiet and is one of the quietest generators we have used in the lab. Fourth, I love that there is less risk of running out of nitrogen as I always have a 24/7 supply when needed. Lastly, the NITRO-GEN+ is so easy to use that students in the Moyo Lab can use it with little training.”With user-friendly features and portability, the NITRO-GEN+ has proven to be a game-changer for the Moyo Lab, ensuring they never run out of nitrogen while simplifying lab operations.<h4>Making the Right Choice for Your Lab</h4>To assist labs in selecting the best nitrogen generator for their needs, Organomation offers a generator recommendation chart that matches evaporator models with the most suitable generator options. Additionally, their customer service team is always available to help labs find the best solution for their workflow requirements.<blockquote>Presenter: David Oliva (General Manager of Organomation)One of Oliva’s favorite responsibilities is visiting academic institutions and environmental laboratories around the world. He was named to the 40 Under Forty Class of 2022 from the Worcester Business Journal and is a winner of a B2B Innovator Award from Demand Gen Report.</blockquote>

Organomation: Why Laboratories are Switching to Nitrogen Generators

Why Laboratories are Switching to Nitrogen Generators

Explore how nitrogen generators enhance lab safety and efficiency. Learn how to cut costs and ditch gas cylinders in Organomation's latest webinar.

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