In this technical tip we are pleased to bring you some valuable guidelines for Gas Chromatography (GC) related to installation, from column conditioning to installation testing and through leak checks. Ensuring proper column installation and performance is crucial for accurate and reliable analysis. Let's dive into some important good practices:<h4>Column Conditioning</h4><ul><li>Allow sufficient time for the carrier gas to flow through the column to purge any oxygen that may be in the system.</li><li>Raise the temperature of the column to the maximum isothermal operating temperature that is listed on your individual GC Column Test Report. Maintain this temperature until a constant baseline is achieved. Conditioning times will depend on the phase identity and thickness, with thicker films taking longer to stabilize. In order to minimize the downtime of the instrument, columns can be conditioned overnight at the maximum isothermal temperature.</li></ul><h4>Installation Testing</h4><ul><li>Inject a detectable unretained sample, such as methane for an FID, to determine dead volume time and linear gas velocity at the desired column temperature. Adjust gas pressure for optimal flow depending on carrier gas selection.</li><li>The non-retained peak must have ideal peak shape or installation is faulty and needs to be redone.</li></ul><h4>Checking for Leaks</h4><ul><li>Use a thermocouple-thermometer to check for leaks. It is highly sensitive to H2, He, and N2 and will not contaminate the instrument or column. Liquid leak indicators are not recommended for capillary columns. There is the risk of drawing the liquid into the column or fittings and contaminating the system.</li><li>Any carrier gas that is leaking from the column will alter the conductivity across the thermocouple. As such, just watch for fluctuations within the temperature reading, which would indicate a possible leak near the location of the thermocouple. This prevents any contact and possible contamination of the column.</li></ul>Note: If Vespel® ferrules are being used, leakage can occur after the initial heating phase due to ferrule deformation. Be sure that the fitting is re-tightened after this initial heating phase, then carefully check all corrections for leaks.Remember, following these practices will contribute to the optimal performance and longevity of your GC columns, reducing downtime due to system maintenance.

Gas Chromatography (GC) Column Conditioning, Testing and Checks

🎤 Presenter: James Harynuk (University of Alberta, Edmonton, Canada)💾 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/28909">PDF presentation</a><blockquote>💡 Book in your calendar: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/787">17th Multidimensional Chromatography Workshop (MDCW)</a> 13 - 15. January 2026</blockquote><h3>Abstract</h3>In Canada, more than one third of Canadians aged 18-44 reported using cannabis at least once in 2023 with about 10% of Canadians in this age range reporting daily or almost daily use. While there are many ways in which cannabis can be consumed, the most popular modes of consumption for Canadians remain the smoking of dried cannabis (65% of legal sales), followed by inhaled extracts (~25% of legal sales). Vaping (not necessarily of cannabis extracts) is particularly popular among younger Canadians, with 14% of youth aged 15-19, and 20% of adults aged 20-24 reporting past-30-day vaping.Consequently, there is a clear need to characterize these exposures and investigate the impacts of these exposures on humans. Recent work in our laboratory has focused on the characterization of mainstream particle and volatile composition of vape and cannabis smoke as well as exposure studies to explore impacts of smoke on lung cells. In addition to presenting results studying the impacts of these direct exposures to cannabis and vaping, some preliminary results exploring the accumulation and retention of smoke by fabrics, representing potential third-hand exposures will be presented.

Investigating Impacts of Cannabis Tobacco and Vapes on Lung Cells Using GC×GC-MS (James Harynuk, MDCW 2025)

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 23rd June 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you application note by Shimadzu, posters by Agilent Technologies / ASMS and Thermo Fisher Scientific / ASMS and presentation by William &amp; Mary / MDCW!<h3>1. Agilent Technologies / ASMS: Improved Determination of Polychlorinated Biphenyl Compounds by US EPA Method 1628</h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ps_5977c_pcb_hydroinert_column_asms_2025_mp_360_en_agilent_8db06d5b24.pdf">Full PDF for download</a></li></ul><h5>Polychlorinated Biphenyl (PCBs) and the Environment&nbsp;</h5>Polychlorinated Biphenyls (PCBs) are synthesized compounds that belong to the chlorinated hydrocarbon family of compounds. PCBs were used in a variety of industrial applications such as electrical components, plasticizers and pigments/dyes, until they were banned in 1979 by the Toxic Substances Control Act (TSCA)1 . PCBs are considered to persistent organic pollutants (POPs) as they do not easily degrade in the environment. PCBs can be found in the air, water, and soil and have been known to bioaccumulate in marine life.The EPA has recently developed a low-resolution mass spectrometry method that can calibrate 65 PCBs congeners and screens for all 209 using labeled PCB compounds for direct and indirect quantitation2 . The 65 congeners are targeted for calibration and quantitation due to specific factors described in the method2 . As with most EPA methods, the prescribed methodology utilizes helium as a carrier gas. The recommended column for this analysis makes adequate separation and quantitation more challenging. To achieve separation that meets the method criteria, the run time is over 40 minutes long. By using a column better suited for PCB congener separation and hydrogen as the carrier gas, superior separation can be achieved in under 20 minutes, resolving previously co-eluting analytes.<h4>Experimental&nbsp;</h4><h5>System configuration using hydrogen carrier gas&nbsp;</h5>The Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=8890%2F5977C+GC%2FMSD">8890/5977C GC/MSD</a> equipped with the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=HydroInert+Ion+source">HydroInert Ion source</a> was operated in selective ion monitoring (SIM) mode for this analysis.<h4>Conclusions</h4><h5>Faster Analysis, Superior Separation Achieved&nbsp;</h5><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=DB-XLB+column">DB-XLB column</a> offers enhanced selectivity for PCB congeners, resulting in previously co-eluting congeners to separate.&nbsp;</li><li>Selectivity is easily achieved operating the MSD in SIM mode.&nbsp;</li><li>The method meets the 10ppb detection limit for all the quantified compounds.</li><li>The HydroInert ion source allows hydrogen carrier gas to be used for more rapid analysis.</li></ul><h3>2. Shimadzu: Simultaneous Analysis of Synthetic Musk Compounds in Water Using a Triple Quadrupole GC-MS System</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_09_ssk_020_en_4ae628cef8.pdf">Full PDF for download</a></li></ul>User Benefits:<ul><li>Using a GC-MS/MS, synthetic musk compounds in water can be accurately quantified with high sensitivity.</li><li>Supporting effective environmental monitoring in water and risk assessment using GC-MS/MS</li></ul>Synthetic musk compounds (SMCs) are synthetic organic substances designed as substitutes for natural musk and are widely used in various household products. During everyday activities such as showering and washing, these compounds are released into wastewater. However, current wastewater treatment processes cannot completely remove SMCs, allowing them to enter aquatic ecosystems. As highly bio-accumulative organic compounds, SMCs can cause both acute and chronic toxicity in aquatic organisms. They are also known to cause endocrine disruption when accumulated in the human body1-3) . Due to these potential risks, continuous monitoring of SMCs in water is essential. The main analytical methods for detecting SMCs in water include liquid-liquid extraction (LLE), solid-phase extraction (SPE), and solid-phase microextraction (SPME). Liquid-liquid extraction method requires a large amount of solvent and long preparation time but has the advantage of simultaneously extracting multiple organic compounds 4) . In this application news, 15 types of SMCs in water were simultaneously analyzed using the gas chromatography method with liquid-liquid extraction method.<h4>Analytical conditions</h4>In this newsletter, SMCs in water were analyzed using <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=3&amp;search=GCMS-TQ8050+NX">GCMSTQ8050 NX</a> of SHIMADZU (Figure 1). The instrumental detailed analytical conditions of instrument and the MRM conditions for each compound were shown in Table 1 and 2, respectively.<h4>Conclusions&nbsp;</h4>The simultaneous analysis of 15 SMCs in water was performed using the SHIMADZU GCMS-8050 NX system. The coefficient of determination(R2) of the calibration curve for all SMCs were 0.99 or higher. The LOD and LOQ were ranged from 0.003 to 0.020 ng/mL and 0.01 to 0.07 ng/mL, respectively. The recovery test results were between 86.3 % and 106.4 %, with a relative standard deviation (RSD) of 0.7 % to 4.2 %. This analytical method, using a GC-MS/MS system, provided reliable quantitative results for 15 synthetic musk compounds in water samples and demonstrated high sensitivity and efficiency.<h3>3. Thermo Fisher Scientific / ASMS: Performance evaluation of GC-MS/MS for Dioxin analysis with amendments to EU Regulations 644/2017 and 771/2017 for food and feed&nbsp;</h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/PO_298_ASMS_25_performance_evaluation_GC_MS_MS_dioxin_analysis_po298_na_en_8721a5f8dc.pdf">Full PDF for download</a></li></ul>Polychlorinated dibenzo-p-dioxins/furans (PCDD/F), or dioxins, are persistent organic pollutants (POPs) that can accumulate within food chains due to their chemical stability and high fat solubility, posing health risks to humans through food consumption1 . Current regulations monitor food and feed for dioxins, with maximal allowable levels for PDCC/Fs in feedstuffs at the pg•g-1 concentration range2 . However, a recent review process has proposed a reduction of up to 40% in these levels by 2024 for certain feed items, such as animal/milk/egg fats (1.0 pg•g-1), fish oil (3.5 pg•g-1), and fish feed (1.0 pg•g-1)3 . Since 2014, the European Commission has permitted the use of gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS) for food and feed analysis as an alternative to GC-high resolution mass spectrometry (HRMS)4,5 . With the proposed reduction in maximum limits, the performance of current instrumentation to achieve these targeted limits must be assessed.Laboratories face challenges in maintaining consistent sensitivity to detect trace levels of dioxins in complex food matrices and in reporting various regulatory requirements for PCDD/ F analysis6,7 . This study used the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/485">Thermo ScientificTM TSQTM 9610 triple quadrupole GC-MS/ MS</a> system with the NeverVentTM advanced electron ionization (AEI) source to demonstrate compliance with the proposed regulatory limits for PCDD/F in food and feed samples. The aim was to ensure consistency with previously determined concentrations of PCDD/F in food and feed matrices and meet current compliance with the EU regulations.<h4>Materials and methods</h4>Data was acquired, processed, and reported using the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76">Thermo Scientific Chromeleon Chromatography Data System (CDS) software</a>, version 7.3. Integrated instrument control ensures full automated setup of the Dioxin analytical workflow through the eWorkflow which provides optimized instrument / quantification methods, view settings for time efficient data evaluation and customizable report templates. Isotopic dilution quantification is performed automatically in real time with the incorporated custom variable and formula functionality eliminating the need for exporting to external software packages.<h4>Conclusions&nbsp;</h4>The results of these comprehensive experiments demonstrate that the TSQ 9610GC-MS/MS system, configured with the NeverVent AEI source and controlled using Chromeleon CDS software together with the Dioxin eWorkflow, can deliver reliable regulatory compliant performance for the quantification and confirmation ofPCDD/Fs food and feedstuffs:&nbsp;<ul><li>Fentogram level sensitivity performance for ultra trace level determination of PCDD/F within food and feed samples&nbsp;</li><li>Check standard performance was within quantitation and ion ratio thresholds for regulatory method compliance at femtogram levels.&nbsp;</li><li>Accurate and precise quantitation at both current and newly adopted maximum limits for PCDD/F in food and feed.&nbsp;</li><li>Chromeleon CDS software, version 7.3, provides an integrated platform, with the ability to automatically setup, easily acquire, process and report compliant data in a fully regulated environment, eliminating the need for using external spreadsheet programs.&nbsp;</li><li>Chromeleon eWorkflows, available from Thermo Scientific also provide error-free execution of each analysis to meet standard operating procedure (SOP) requirements, further simplifying the user</li></ul><h3>4. William &amp; Mary / MDCW: Method optimization of fingermark residue using comprehensive two-dimensional gas chromatography&nbsp;</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/FL_07_Macturk_MDCW_2025_Oral_Presentation_4c2c820f98.pdf">Full PDF for download</a></li></ul>Fingermarks—smudged or incomplete fingerprints—may lack value for direct identification but can still offer critical information through their chemical residue. This study explores the potential of nontargeted chemical analysis of fingermark residue to determine donor characteristics such as sex and age. Using comprehensive two-dimensional gas chromatography (GC×GC), the team sought to enhance analytical resolution and method efficiency.<h4>Experimental Approach</h4>Researchers first collected fingermark residue using cotton swab extraction, followed by centrifugation and sample preparation. A GC×GC method was optimized by adjusting parameters like modulation period, hot pulse time, oven hold times, and ramp rate. Multiple method configurations were tested for chromatographic resolution, and the optimized helium-based method was later translated for use with hydrogen carrier gas using modeling tools.<h4>Results</h4>Method optimization led to significant improvements in peak separation, enabling identification of various compound classes including sterols, fatty acid methyl esters, fatty alcohols, and steroids. Additionally, unexpected anthropogenic substances such as sunscreen agents and plasticizers were detected. Hydrogen-based methods were able to achieve comparable separation quality, with the “H₂ Translate” method offering the highest number of identifiable peaks.<h4>Conclusion</h4>This study demonstrates that nontargeted GC×GC analysis is effective for resolving both endogenous and exogenous compounds in fingermark residue. The optimized methods not only improve forensic chemical profiling but also support a successful transition from helium to hydrogen as a carrier gas—promoting sustainability without compromising analytical performance.

News from LabRulezGCMS Library - Week 26, 2025

Article

Application

Academy

Video

Environment

Presentation

Poster

The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography Workshop

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

Phenomenex

Agilent Technologies

Thermo Fisher Scientific

Waters Corporation

Quantification of trace levels of pesticides in food can be challenging. Identifying residual pesticides in complex matrices requires adequate sample workup and appropriate instrumentation.
Agilent offers a comprehensive workflow for pesticide screening and quantitation by combining QuEChERs sample preparation and multi-platform GC/MS analysis. This presentation will cover the workflows utilizing GC/MSD for pesticide screening and quantitation, targeted pesticide screening with enhanced sensitivity and selectivity with GC/TQ, and comprehensive trace-level screening and quantitation with retrospective analysis capabilities with high-resolution accurate mass analysis using GC/Q-TOF.
Key Learning Objectives/What attendees will learn:
<ul>
<li>Suspect screening and quantitation by GC/MSD</li>
<li>Targeted selective and sensitive quantitation by GC/TQ</li>
<li>Trace level screening and quantitation by GC/Q-TOF</li>
</ul>
Who Should Attend:
Food scientists and chemists interested in pesticide analysis by GCMS
<blockquote>
Presenter: Erinn O&#39;Neill (GCMS Applications Scientist, Agilent)
</blockquote>
<blockquote>
Erinn O’Neill is a GCMS Pre-Sales Application Scientist for Agilent in Wilmington, Delaware. She graduated from the University of North Carolina at Chapel Hill with a Ph.D. in Chemistry in 2019, where she focused on identifying novel chemical structures synthesized by plant-pathogenic bacteria. Before that, she obtained a Bachelor’s degree in Chemistry from Drew University in New Jersey, where she studied reactions between atmospheric aerosol surrogates and trace pollutants.
</blockquote>

Agilent: A multi-platform approach for screening and quantitating pesticide residues in food

A multi-platform approach for screening and quantitating pesticide residues in food

This presentation will cover the workflows utilizing QuEChERs sample preparation and GC/MSD for pesticide screening and quantitation.

Screening and quantitating pesticide residues in food

Key Learning Points:
<ul>
<li>Learn how to approach analyzing for PFAS, it is not rocket science like they made it out to be</li>
<li>Become aware of Sporadic PFAS Contamination</li>
<li>Understand how to identify false positives</li>
<li>Require all analysis quality control and samples to be analyzed in replicates to identify false positives</li>
</ul>
Who Should Attend:
<ul>
<li>Anyone who is new or has used Quechers and needs to have an update and an insight on Quechers method</li>
</ul>
<blockquote>
Presenter: Duilio Romanello (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Duilio Romanello graduated with his Bachelors of Science in Pharmaceutical Chemistry and Technology from University of Bologna. Duilio then joined Phenomenex in 2008 as an Inside Technical Sales Consultant becoming Team Leader in Italy for GC/SPE in 2010 and then for the Environmental &amp; Food Team. Since 2016 he has been covering the role of Account Manager for the South of Italy working remotely and acting as GC Specialist. Since November 2023 he is Senior Technical Specialist for the Technical team at Phenomenex.
</blockquote>

Phenomenex: Quechers 101: Background and Updates

Quechers 101: Background and Updates

Learn how to approach analyzing for PFAS, it is not rocket science like they made it out to be

Key Learning Points:
<ul>
<li>Understand the benefit of using SPE than other sample preparation techniques </li>
<li>Learn the basic protocol for SPE method and separation modes</li>
<li>Dig into reverse phase SPE typical protocol, and solid phase extraction media</li>
</ul>
Who Should Attend:
Anyone beginning with solid phase extraction (SPE) technique, or anyone struggling with method sensitivity
<blockquote>
Presenter: Grace Guo (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Grace Guo graduated from the Johns Hopkins University with a Master’s degree in Material Science and Engineering. She joined Phenomenex Technical Team in 2017 providing technical support globally. With more than 8 years of experience on SPE, HPLC and GC, she delivered 50+ seminars and webinars globally covering food and environmental, clinical, pharma and biopharma industry. 
</blockquote>

Phenomenex: Solid Phase Extraction Introduction and Theory

Solid Phase Extraction Introduction and Theory

Understand the benefit of using SPE than other sample preparation techniques.

Who Should Attend:
Anyone new to SPE who wants to get familiar with the basics of SPE method development. Anyone who has a basic understanding of SPE and would like to learn how to improve their extractions. 
Key Learning Points:
<ul>
<li>Understand how to develop SPE methods from start to finish.</li>
<li>Receive general methods to use as starting points.</li>
<li>Learn when and how to optimize SPE methods, and discover new tips and tricks to make SPE method development easier.</li>
</ul>
<blockquote>
Presenter: Koen Askamp (Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Koen Askamp is a Technical Specialist at Phenomenex. He was awarded his BSc and MSc degrees in Molecular Life Sciences at Wageningen University in the Netherlands and joined Phenomenex in 2020 as Technical Sales Consultant. Koen became part of Phenomenex’s global technical support team in 2022 and assists laboratories in training chromatographers and developing analytical methods. 
</blockquote>

Phenomenex: Solid Phase Extraction Method Development

Solid Phase Extraction Method Development

Learn when and how to optimize SPE methods, and discover new tips and tricks to make SPE method development easier.

<h4>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</h4>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.<h5>Why attend?</h5><ul><li>Comprehensive Learning: Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li>Expert Insights: Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li>Regulatory Compliance: Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3>Episode #5: General Sample Preparation | F&amp;E Summer School - Day 2 - Module 1</h3>Sample preparation is a key aspect in the analytical workflow and heavily determines the quality of the analysis. Solid Phase Extraction is a fundamental sample preparation technique widely used across all areas of analytical chemistry. Whether new to SPE or seeking a refresher, this webinar will introduce the basics of sample preparation and provide practical insights and technical background on the benefits when choosing SPE over another form of sample preparation, especially for analytes in complex matrices, such as the ones often encountered in Food and Environmental analysis. Join us in exploring SPE key parameters and best practices for implementing successful SPE methods. The session will combine PowerPoint slides with videos describing good practices and showing a practical example on the complex analysis of PFAS.Our guest speaker Chiara Sarti from Cranfield University, Bedford UK, will share her research results on the work with new dual layer cartridges to extract PFAS from different environmental samples.<h5>What you'll learn:</h5><ul><li>Understanding SPE fundamentals</li><li>Making SPE simple with water-wettable sorbents</li><li>Verifying successful SPE implementation</li></ul><blockquote>Presenter:&nbsp;Xavier Rodríguez (Business Development Manager Chemistry Group, Southern Europe, Waters)Xavier is part of the European Market Development Team. He works as an Application Specialist with focus on sample prep and has more than 20 years of experience in solving sample prep challenges.Presenter:&nbsp;Chiara Sarti (Ph.D. Student, Department of Chemistry "Ugo Schiff", University of Florence)</blockquote>

Waters Corporation: The Waters 2024 Virtual Summer School

General Sample Preparation

Join us in exploring SPE key parameters and best practices for implementing successful SPE methods. 

<h4>The Waters 2024 Virtual Summer School - An Educational Journey to Master Food &amp; Environmental Analysis</h4>Unlock the full potential of LC-MS techniques with our immersive and educational sessions at the Waters Virtual F&amp;E Late Summer School 2024. From September 24th to 26th, engage with leading experts and discover cutting-edge methods for environmental and food analysis.<h5>Why attend?</h5><ul><li>Comprehensive Learning: Dive deep into advanced LC-MS techniques and gain practical knowledge to enhance your laboratory's analytical capabilities.</li><li>Expert Insights: Learn from industry leaders and gain firsthand experience through detailed modules on chromatography, mass spectrometry, and sample preparation.</li><li>Regulatory Compliance: Stay ahead with the latest insights on EU regulations for PFAS analysis in food and water, ensuring your lab meets stringent standards.</li></ul><h3>Episode #6: Automated Sample Preparation | F&amp;E Summer School - Day 2 - Module 2</h3>This Module builds on the previous one by adding automation to the sample preparation methods. The Andrew+™ pipetting robot offers fully automated liquid handling using electronic pipettes and labware holders called Dominos for a full walk-away automation solution.Creating the connected laboratory, Andrew+ is part of the OneLab™ ecosystem, executing laboratory protocols designed in OneLab software. This flexible architecture enables you to effortlessly transition from laborious manual pipetting procedures to error-free, fully-robotized lab workflows – without any knowledge of programming, laboratory robotics or automation engineering. and explains processes the Andrew+ pipetting robot can take over in your lab.The European Union has adopted Commission Recommendation (EU) 2022/1431 to monitor PFAS in fruits, vegetables, milk and baby food. To achieve quantification at lowest levels of PFAS in food matrices, sample preparation is required which comprise of many pipetting steps and can be time-consuming and error prone. We will demonstrate an automate workflow for the analysis of PFAS in milk using a pipetting robot and stacked dual-phase SPE cartridges to meet EU 2022/1431 levels.<h5>What you'll learn:</h5>Possibilities to automat liquid handling processes in LC and LC-MS e.g.<ul><li>Serial dilution</li><li>Calibration curve</li><li>Solid Phase Extraction (SPE)</li></ul><blockquote>Presenter:&nbsp;Xavier Rodríguez (Business Development Manager Chemistry Group, Southern Europe, Waters)Xavier is part of the European Market Development Team. He works as an Application Specialist with focus on sample prep and has more than 20 years of experience in solving sample prep challenges.Presenter:&nbsp;Daniel Ng PhD (Principal Scientist, Waters Corporation)Daniel Ng received his PhD from the University of Manchester in mass spectrometry proteomics. He worked for 5 years at the Waters mass spectrometry headquarters in Wilmslow, UK, as a service support development engineer specializing in mass spectrometry instrumentation. In 2019, he took up a new role as a principal scientist at the International Food and Water Research Centre (Waters) in Singapore focusing on using advanced instrumentation to answer analytical challenges in the food and water industry. Since 2023, Daniel has lead the Food, Environmental and Material Science Analytical Professional Service team in the Asia-Pacific Region, developing analytical solutions to meet key challenges that customers face.</blockquote>

Automated Sample Preparation

The Andrew+™ pipetting robot offers fully automated liquid handling using electronic pipettes and labware holders.

<h4>Key Learning Points:</h4><ul><li>Identify the common challenges associated with solid phase extraction methods &nbsp;</li><li>Understand and troubleshoot the recovery, contamination and reproducibility issues &nbsp;</li><li>Learn how to find and apply solutions to develop robust and reproducible extraction methods for their sample preparation needs</li></ul><h4>Who Should Attend:</h4><ul><li>Any scientists who wants to learn about solid phase extraction and it’s associated challenges, common troubleshooting steps and solutions to develop robust and reproducible extraction methods for their sample preparation needs</li></ul><blockquote>Presnter: Namrata Saxena (Technical Manager, Phenomenex)Namrata is the Technical Manager for the Asia-Pacific region in Phenomenex and is based in Sydney, Australia. As a member of the global technical team, she is responsible for assisting external customers as well as internal marketing and sales teams of Phenomenex for multifarious technical queries. She specifically support company’s bio-products portfolio through external and internal seminars/webinars, trainings and also contribute in biologics related technical content creation.Before joining Phenomenex she had worked as a Product Specialist and spent several years in stationary phase chemistry, column manufacturing and method development groups in a German company Bischoff Chromatography GmbH.Namrata has a post graduate degree with specialization in Analytical Chemistry. Her competence and focus lies in biotherapeutics characterization through liquid chromatography, antibodies and oligonucleotide chemistry, gene therapy and new bio-therapeutic modalities.</blockquote>

Phenomenex: Solid Phase Extraction Troubleshooting Tips and Tricks

Solid Phase Extraction Troubleshooting Tips and Tricks

Identify the common challenges associated with solid phase extraction methods.

Join this live webinar to learn how sample preparation in combination with the right glass quality and a GC-MS/MS analysis allows you to reach factor 1000 lower detection limits for PAH in smoke flavored food samples to meet latest regulatory updates.The European Commission asked the European Food Safety Authority (EFSA) to develop updated consolidated guidance for submission of applications on smoke flavoring primary products under Regulations (EC) No 2065/2003 and No 1321/2013. To reach the requested low detection limits for PAH, it is important to find the right workflow including consumables and an advanced EI source for GC-MS/MS analysis.&nbsp;In this webinar, we will talk you through the workflow and show real food samples with the focus on the analysis of 40 PAH. The key analytical benefits of the workflow include:<ul><li id="isPasted">Complete SPE workflow</li><li id="isPasted">Glass quality that provides the right results for low concentrations</li><li id="isPasted">Ultra low detection limits with Advanced-EI technology on a GC-MS/MS</li></ul>At the end of the webinar, we have time to answer your questions.If you are unable to attend on March 20, please register to ensure you will receive the link to the recording.We are running this webinar on March 25 in German language. <a style="user-select:auto;" target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/4835418/2EEB616DFE5F57C6587BA5984198FE55?partnerref=E.25CMD.EL105.26221.01" fr-original-style="">Click here is you want to sign up for the German session »&nbsp;</a>Additional WebinarsTake advantage of our growing library of convenient and educational recorded webinars and resources. <a style="user-select:auto;" target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/uk/en/home/about-us/events/industrial/analytical-innovations-webinars.html?cid=E.25CMD.EL105.26221.01" fr-original-style="">Visit our webinars page</a><blockquote>Presenter: Petra Gerhards (Regional Marketing Manager EMEA GC&amp;GC-MS and Trace Elemental Analysis, Thermo Fisher Scientific)<div>Petra Gerhards is a Regional Marketing Manager of GC and GC-MS at Thermo Fisher Scientific. She has more than 29 years of experience in the fields of GC-MS, SPE and LC-MS. Since joining the regional team, she has contributed to workflow solutions combining vials and closures with SPE solutions, GC-MS and LC-MS.</div></blockquote>

Thermo Fisher Scientific: Advanced workflow for PAH analysis of smoke flavored foods 

Advanced workflow for PAH analysis of smoke flavored foods

Join this webinar to learn how sample prep, glass quality, and GC-MS/MS achieve 1000x lower PAH detection in smoke-flavored foods to meet new regulations.

<h4>Key Learning Points</h4><ul><li>Understand recovery and reproducibility in the context of Solid Phase Extraction</li><li>Discover the causes of commonly encountered Solid Phase Extraction problems</li><li>Learn how to successfully troubleshoot a Solid Phase Extraction problem quickly and efficiently</li></ul><h4>Who Should Attend</h4><ul><li>Any scientist who is interested in improving their SPE extraction method recovery and reproducibility.</li></ul><blockquote>Speaker: Kevin Zhao (Sr. Technical Specialist, Phenomenex)Kevin Zhao has 5 years of experience in biochemistry research, 4 years of Protein/Cancer research with the CSULA-City of Hope Cancer Collaborative, and over 12 years with Phenomenex. Mr. Zhao is a member of a global Technical Support Team, providing problem-solving, troubleshooting, and application assistance for customers worldwide in the fields of chromatography (liquid and gas) and sample preparation. The industries he supports include pharmaceuticals, biopharmaceuticals, clinical research and toxicology, food safety, environmental analysis, fuels, and specialty chemicals.Mr. Zhao received his B.S. in Biology from California State Polytechnic University, Pomona, his M.S. in Biochemistry from California State University, Los Angeles, and an MBA from the University of the Incarnate Word.</blockquote>

Phenomenex: SPE Troubleshooting: Unlock Maximum Recovery with Expert Tips!

SPE Troubleshooting: Unlock Maximum Recovery with Expert Tips!

Learn how to successfully troubleshoot a Solid Phase Extraction problem quickly and efficiently

SPE Troubleshooting: Unlock Maximum Recovery with Expert

<h4>Key Learning Points</h4><ul><li>Learn how to select the ideal SPE sorbent based on your analytes and impurities.</li><li>Review different SPE separation modes, and SPE stationary phases.</li><li>Walk through step-by-step sorbent selection examples.</li></ul><h4>Who Should Attend</h4><ul><li>Anyone new to SPE who wants to get familiar with SPE retention mechanisms.</li><li>Anyone who has a basic understanding of SPE and would like to explore sorbent options.&nbsp;</li></ul><blockquote>Speaker: Koen Askamp (Technical Specialist, Phenomenex)Koen Askamp is a Technical Specialist in Phenomenex. He was awarded his BSc and MSc degrees in Molecular Life Sciences at Wageningen University in the Netherlands and joined Phenomenex in 2020 as Technical Sales Consultant. Koen became part of Phenomenex’s global technical support team in 2022 and assists laboratories in training chromatographers and developing analytical methods.</blockquote>

Phenomenex: SPE Sorbent Quest: Discovering the Ideal Solution

SPE Sorbent Quest: Discovering the Ideal Solution

Learn how to select the ideal SPE sorbent based on your analytes and impurities.

GCMS webinars focusing on SPE | LabRulez GCMS