Jan Velecký is a&nbsp;researcher at the RECETOX center. In his dissertation, he focuses on machine learning methods for protein engineering. He works at the center within Loschmidt Laboratories, specifically on Stanislav Mazurenko's&nbsp;team. In the interview, he explains what protein engineering is about, why it is important to study protein solubility, and how machine learning can be crucial for human knowledge.<div><div><h5>How did you get into protein engineering?</h5>Since childhood, I&nbsp;had a&nbsp;curious relationship with computers, which led me to a&nbsp;technical high school in Zlín, where I&nbsp;studied information technology. Then I&nbsp;continued at the Faculty of Information Technology at Brno University of Technology. After my bachelor's&nbsp;degree, I&nbsp;realized that I&nbsp;would like to combine computer science with something more tangible, not just living inside the computer. One option was bioinformatics, which I&nbsp;started to pursue during my master's&nbsp;studies. Even then, I&nbsp;began to focus on protein research, specifically choosing the topic of protein solubility for my diploma thesis. And that's&nbsp;what I&nbsp;still do.<h5>Could you explain a&nbsp;bit about what protein engineering actually focuses on?</h5>Protein engineering is, simply put, the design or modification of proteins. Sometimes we create completely new proteins, or more commonly, we modify existing ones. We often proceed based on mutations, i.e., targeted changes that a&nbsp;scientist makes in the protein. To be able to change and modify proteins purposefully, we first need to study them and find out how they work. In its early days, the field aimed at creating mutations that would "damage" the function of a&nbsp;protein. If we manage to disable the protein through mutation, we actually reveal which part of it is essential for its function. That's&nbsp;why protein engineering was initially dubbed protein terrorism.<h5>How can I&nbsp;practically imagine such deliberate protein mutating?</h5>A protein is a&nbsp;linear molecule, a&nbsp;chain of amino acids encoded by a&nbsp;gene. An organism produces it according to the gene and subsequently the protein folds, gaining a&nbsp;shape. The shape then determines the function of the protein. We don't need to know the shape, but we can play with the composition of amino acids. Typically, we replace an arbitrary amino acid with another. We have 20 types of amino acids, so I&nbsp;can, for example, put an alanine, which is very small and neutral, instead of a&nbsp;cysteine, making it ideal for our purposes. If the protein loses its function after such modification, we know that this cysteine is essential for its function or some key property.<h5>Why do you focus on solubility particularly?</h5>Solubility is one of the basic properties; it is crucial for producing new proteins. It determines whether it will be possible to produce the protein in sufficient quantity or quality and at an acceptable cost. It has direct implications in medicine and industry; drugs for stroke in development, for example, are protein-based, so are ingredients contained in washing detergents. Decent solubility is important for yield and thus more efficient production. I&nbsp;specifically deal with methods to estimate changes in protein solubility. This means that where we would usually need a&nbsp;person and material to measure solubility, we could use a&nbsp;computer and estimate solubility in silico, saving both money and time. For example, with the mentioned therapeutics for stroke, we could determine solubility in advance and avoid experiments that wouldn't make sense. To sum up, I&nbsp;try to measure and predict changes in protein properties, especially solubility, after introducing a&nbsp;mutation.<h5>Do you have a&nbsp;personal connection to the field?</h5>Bioinformatics interested me mainly because I&nbsp;saw its potential for the future; it simply seemed exciting to me. By choosing my then-teacher Jiří Hon, who was doing his doctorate at the faculty, as my diploma thesis supervisor at BUT, I&nbsp;also became part of the Loschmidt Laboratories, where I&nbsp;subsequently started working on my own doctorate under the supervision of Dr. Stanislav Mazurenko.<figure class="image"><img style="aspect-ratio:575/764;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MUNI_Proteinovy_vedec_Jan_Velecky_Strojove_uceni_muze_zazarit_tam_kde_uz_lidska_predstavivost_nestaci_877b7af987.jpg" alt="MUNI: Protein scientist Jan Velecký: Machine learning can shine where human imagination falls short" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MUNI_Proteinovy_vedec_Jan_Velecky_Strojove_uceni_muze_zazarit_tam_kde_uz_lidska_predstavivost_nestaci_877b7af987.jpg 117w," sizes="100vw" width="575" height="764"></figure><h5>Can you explain a&nbsp;bit about what the Loschmidt Laboratories are?</h5>The full name is the Loschmidt Laboratories of Protein Engineering, which is our main research focus. We are named after Johann Josef Loschmidt, a&nbsp;Bohemian-Austrian scientist of the 19th century, a&nbsp;founder of modern chemistry. We consist of four teams, two more theoretical, more focused on computational methods, and two experimental, working in the laboratory. What is specific about our work is that although we have specific protein targets we focus on, they serve more as case studies for the methods we create. We develop several software tools for protein engineers, biochemists, or clinical doctors to analyze or modify proteins for their applications. For example, one of our successful and widely used tools is EnzymeMiner, which can find more proteins with the desired function based on the well-studied protein. Thanks to it, we can recycle and use what nature has already invented in the course of evolution. Our work is mainly about developing methods and tools.<h5>Where does your work fall within the focus of the Loschmidt Laboratories?</h5>Researching solubility is about protein optimization. If we develop a&nbsp;new drug, but the yield is so low that it is not enough even for laboratory experiments, we can increase it thanks to protein engineering. I&nbsp;mentioned the drug for stroke; another good example is insulin, which had low solubility earlier and originally used to be derived from pigs, but today, we can produce it artificially in cells and then extract it, making it financially accessible. Solubility prediction is also important in diagnostics. Many diseases are caused by mutation in an individual's&nbsp;genetic code that significantly reduces the solubility of a&nbsp;particular protein. And since insoluble proteins can even be toxic, there is a&nbsp;potential use in personalized medicine too.<h5>If I&nbsp;understand correctly, the role of IT in your field is primarily to save time and money. But does machine learning have any other specific advantages?</h5>Certainly. Let's&nbsp;say that all the problems a&nbsp;person solves can be well managed if they are imaginable in two to four dimensions. However, once there are, say, a&nbsp;hundred dimensions, finding interdependencies and explaining the phenomena and behaviours that lead to them is definitely not trivial. This is where machine learning can shine, as it has no limitations in the possible number of dimensions it can think in and can find what is hidden from us.<h5>How can you be sure that the information you obtain this way is reliable?</h5>Naturally, we have methods to verify reliability. The basis is that we train the machine learning model from data with known outcomes. However, we do not show the model all the data we have. The data we keep aside then serves to test the model. Machine learning is also about experimentation. It's&nbsp;not like you design a&nbsp;model and it works straight on.And thanks to today's&nbsp;availability of computational hardware, we are putting into practice what was previously unimaginable. After all, the cost per unit of computation has dropped a&nbsp;quadrillion times since the 1950s when the foundations of machine learning were laid.<h5>Where is the field heading and what are its ambitions?</h5>There is a&nbsp;whole array of unresolved problems. The latest major challenge solved was the protein structure prediction problem. Now we know what the shape of a&nbsp;protein molecule will be based on its genetic code. This is an important advancement because, as I&nbsp;said, the function depends on a&nbsp;shape. Thus, I&nbsp;think we will now see many problems in molecular biology solved in quick succession. If I&nbsp;were to put it on a&nbsp;timeline, we used to mutate proteins to find out how they work. Today, we are redesigning them. In the future, we will be ordinarily creating completely new proteins, supported not only by the development of machine learning but also by robotics and other high-throughput methods that will enable us to collect data for machine learning.<h5>Do you think the development of AI could threaten some jobs in science?</h5>In my opinion, the development of AI will improve the lives of scientists because it will make repetitive and boring work easier. I&nbsp;don't think AI is targeting any specific positions. Proofreaders and translators might be needed less. In other positions, it will actually increase efficiency and thus the amount of work completed. Someone who now characterizes five protein variants a&nbsp;week in the lab might one day do five thousand.<h5>What are your personal vision and scientific ambitions?</h5>I would like my work to advance the field of protein engineering so that the field can continue to build on it. Right now, I&nbsp;want to focus mainly on completing my doctorate. In the future, I&nbsp;would like to stay in research. However, I&nbsp;want to experiment a&nbsp;bit at the same time. It could be an experience from research in the commercial sphere or a&nbsp;voyage into a&nbsp;new domain where I&nbsp;could apply my machine-learning skills. Not stopping broadening my horizons.</div></div>

Protein scientist Jan Velecký: Machine learning can shine where human imagination falls short

In 2025, the 16th workshop will be hosted in person in Liege, Belgium. The workshop will be shared between key speaker presentations, flash presentations, poster presentations, and focus group discussions on the challenges and the futures of the field. The workshop is dedicated to all multidimensional techniques.<h3>Program</h3>The Guidebook contains the program and all other pertinent conference information.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4750">Final Program (On-line)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.multidimensionalchromatography.com/uploads/5/8/9/1/58913545/_final_16mdcw_guidebook.pdf">Final Guidebook (PDF)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.multidimensionalchromatography.com/uploads/5/8/9/1/58913545/_global_abstract.pdf">Abstract Book (PDF)</a></li></ul>We hope to see you there!<h3>Focus Groups 2025</h3><h5>Guided Discussion 1:​ Transition to green chemistry, challenges and opportunities for analytical revolution</h5><ul><li>Moderators: Melissa Dunkle (Dow Benelux), Pierre Giusti (TOTAL Energies), Jef Focant (Université de Liège)</li></ul>Over the last five years, the political actions to minimize climate change have deeply modified the landscape of chemical and energy industries. These ambitious targets are currently driving the research and development effort to greener solutions for material, chemical, and energy production. &nbsp; During this discussion group, we will discuss with key actors of the field to see the challenges and opportunities for analytical technology in this green revolution. &nbsp;<ul><li>What is the biggest impact of the green revolution on your work? &nbsp;</li><li>How have these changes impacted your work as an analytical scientist? &nbsp;</li><li>What are the biggest challenges you aim to tackle in the next 3 years? &nbsp;</li><li>How has your knowledge on non-renewable matrices helped you to address these challenges? &nbsp;</li><li>What are the opportunities for separation sciences in tackling those challenges? &nbsp;</li><li>Any success stories you can share with the audience? &nbsp;</li></ul><h5>Guided Discussion 2: Teaching GC×GC to students, post-docs, and staff</h5><ul><li>Moderators: Chris Freye, Colleen Ray, and Michelle Corbally (Los Alamos National Laboratory)</li></ul>Teaching GC×GC to people in different stages of their careers, especially with diverse analytical chemistry backgrounds, often requires a different approach. Those who learn GC×GC as part of their graduate school experience have multiple years to master the technique whereas people who are trained on the job (post-docs and staff) have significantly less time to attain the same level of proficiency. This discussion will focus on instructional approaches and difficulties in training people with various backgrounds on GC×GC. Special attention will be given to common difficulties encountered regardless of career level.<blockquote><h4>OLD SPONSORS 2025</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/">LECO</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.jeolbenelux.com/">JEOL</a></li></ul><img style="aspect-ratio:1283/384;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_MDCW_2025_Gold_Sponsors_97685a5688.jpg" alt="MDCW: MDCW 2025 Gold Sponsors." width="1283" height="384"></blockquote><h3>Short Course - 2025</h3>The 2025 Short Course registration is now closed. Thank you for your interest.<h4>A Beginner’s Guide to Multidimensional Chromatography</h4><ul><li>Instructors: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=Pierre-Hugues+Stefanuto">Pierre-Hugues Stefanuto</a>, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=Katelynn+Perrault+Uptmor">Katelynn Perrault Uptmor</a>, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=Dwight+Stoll">Dwight Stoll</a>, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/articles?search=Petr+Vozka">Petr Vozka</a></li></ul><h5>Course Description</h5>So...you want to do multidimensional chromatography? If you are getting started in the field using either liquid or gas chromatography, you’re in the right place. This course will cover a brief history and introduction to both multidimensional gas chromatography and multidimensional liquid chromatography. Discussion will also include basic system components and data handling strategies to apply after acquiring your data. A hands-on portion of the course will also include familiarization with common system components and consumables for both GC and LC, as well as the opportunity to use a commercial GC×GC instrument.<h5>Target Participants</h5>This course is intended to be an initial touchpoint for those who are looking to explore multidimensional chromatography as a new option/capability, or who might be using it for the first time. The course is intended for new users to obtain a background on the techniques as a primer to the workshop. &nbsp;Advanced topics will not be discussed.<h5>Course Logistics</h5><ul><li>Morning Session (8:30 AM – 12:30 PM): Pentahotel Liège, Bd de la Sauvenière 100, 4000 Liège</li><li>Afternoon Session (2:00 PM – 5:00 PM): University of Liège Sart Tilman Campus, Quartier Agora, Allée du Six Août 11, 4000 Liège</li></ul>Lunch and coffee will be provided. Transportation to/from the university for the afternoon session will be organized for the group. &nbsp;<h5>Cost</h5>A $50 fee is required to reserve a spot in the course. 20 seats are available. An expression of interest form will be available to indicate interest in a seat within the course. On November 1st, participants will be informed about seat availability and the payment process will be communicated.<blockquote><h4>SILVER SPONSORS SPONSORS 2025</h4><ul><li>SpectralWorks</li><li>GC Image</li><li>SepSolve Analytical</li><li>TRAJAN</li><li>Exxon Mobil</li><li>GL Sciences</li><li>RIC Group</li><li>Inter Science</li><li>TotalEnergies</li><li>SRA Instruments analytical solution</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_SILVER_SPONSORS_SPONSORS_16th_Multidimensional_Chromatography_Workshop_MDCW_63e742d8ce.jpg" alt="MDCW: SILVER SPONSORS SPONSORS - 16th Multidimensional Chromatography Workshop (MDCW)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MDCW_SILVER_SPONSORS_SPONSORS_16th_Multidimensional_Chromatography_Workshop_MDCW_63e742d8ce.jpg 245w," sizes="100vw" width="1388" height="764"></blockquote><h5>Part I (1 hr) – History, Terminology, Fundamental Concepts</h5><ul><li>Outline (Total Time ~ 4 hrs)</li></ul><ol><li>Brief history of the development of multidimensional separations</li><li>Terminology</li><li>Fundamental Concepts<ol><li>In what ways are multidimensional separations useful for analytical chemistry / measurement science?</li><li>First and second separations should be orthogonal / complementary</li><li>Fast second dimension separations are important to avoid undersampling</li><li>Structured chromatograms can provide chemical insight and facilitate data interpretation</li><li>Highlights of an example data processing workflow – from raw data to actionable information &nbsp;</li></ol></li></ol><h5>Part II (1.25 hr) Introduction to Multidimensional Gas Chromatography</h5><ol><li>Method basics<ol><li>Column selection</li><li>Method parameters</li><li>Carrier gas choices</li><li>Detector considerations</li></ol></li><li>Modulator selection with a focus on current market options<ol><li>Thermal modulators</li><li>Flow modulators</li><li>Other commercial options</li></ol></li><li>Method development made simple</li><li>Data preprocessing and initial handling</li></ol><h5>Part III (1.25 hr) Introduction to Multidimensional Liquid Chromatography</h5><ol><li>Modes of multidimensional separation commonly used with LC<ol><li>Heartcut</li><li>Multiple heartcut / selective comprehensive</li><li>Fully comprehensive</li></ol></li><li>Interfaces used for multidimensional LC (i.e., the hardware that does the transfer from first to second dimension)</li><li>Common use cases of multidimensional LC illustrated using examples from industry and academic research<ol><li>Evaluating peak purity</li><li>Unknown identification via multidimensional and MS or NMR detection</li><li>Multi-stage separation with analyte transformation between stages</li><li>Multi-attribute methods</li><li>Making complete analysis of moderately complex samples attainable in a reasonable analysis time</li><li>Digging deeper – comprehensive separations for comprehensive analysis</li></ol></li><li>Introduction to method development strategies</li></ol><h5>Part IV (15 min) Wrap-up and Q&amp;A</h5><ul><li>Travel to University of Liege (30 min)</li><li>Lunch (45 min)</li><li>Part V (3 hours) &nbsp;</li></ul>Participants will have the opportunity to familiarize with a variety of GC and LC components used for multidimensional systems including:<ul><li>LC: Interface, valves, columns, acquisition software&nbsp; GC: Detector components, inlet components, columns, cutting tools, column connectors, source components</li></ul>Participants will have the opportunity to inject basic samples on a LECO Peg 4D and LECO Peg BT 4D CF system, and to interact with 2D LC software setup.<blockquote><h4>SHORT COURSE SPONSORS 2025</h4><ul><li>Acesss</li><li>Certech</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_MDCW_2025_Short_Course_Sponsors_17c5136804.jpg" alt="MDCW 2025: Short Course Sponsors." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MDCW_MDCW_2025_Short_Course_Sponsors_17c5136804.jpg 245w," sizes="100vw" width="1314" height="406"><h4>ARDS SPONSOR 2025</h4><ul><li>SCSC</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_MDCW_2025_Award_Sponsor_4db6e66b12.jpg" alt="MDCW 2025: Award Sponsor." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MDCW_MDCW_2025_Award_Sponsor_4db6e66b12.jpg 245w," sizes="100vw" width="1243" height="485"><h4>MEDIA SPONSORS 2025</h4><ul><li>LCGC International</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/">LabRulezGCMS</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/">LabRulezLCMS</a></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_MEDIA_SPONSORS_16th_Multidimensional_Chromatography_Workshop_MDCW_a28c91bcc9.jpg" alt="MDCW: MEDIA SPONSORS - 16th Multidimensional Chromatography Workshop (MDCW)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MDCW_MEDIA_SPONSORS_16th_Multidimensional_Chromatography_Workshop_MDCW_a28c91bcc9.jpg 245w," sizes="100vw" width="1001" height="277"></blockquote>

16th MDCW Focus Groups and Short Course 2025

Agilent’s OpenLab Software portfolio is a very useful approach for integrating the analytical workflow in mass spec analyses. It can easily be employed with NIST 2023 Search and associated libraries for unknown identifications.<ul><li>Some tips on using NIST MS Search for unknown identifications</li><li>Search with Agilent GC MSD/OpenLab CDS transferred to NIST MS Search</li><li>Information supplied from Agilent (Emily Adams, Product Support Engineer)</li></ul><h5>Topics Discussed</h5><ol><li>Sending spectra for search from OpenLab to external NIST MS Search Program</li><li>Processing OpenLab Files in Agilent MassHunter</li><li>Export files in netCDF (AIA) format for processing with AMDIS, Wiley KnowItAll, etc.</li><li>Data file locations in OpenLab file directories</li><li>Searching using NIST dll with results returned for internal display in OpenLab</li><li>Library format supported by OpenLab and interconversion of library formats with NIST Lib2NIST utility program</li><li>Adding an entry to existing user library or creating first entry in a new user library</li><li>Initial Settings for NIST Search V3.0 in EI and MSMS (tandem) modes</li><li>Extensive user help found on “Agilent OpenLab Help &amp; Learning” website</li></ol><h4>1) Can you send spectra to NIST’s MS Search program?</h4>Yes! The simplest way is to right-click on the spectrum in OpenLab CDS and select Send spectrum to NIST MS Search program. (Note that this option is greyed out until NIST’s MS Search package is installed on the same PC as OpenLab CDS.)<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_Can_you_send_spectra_to_NIST_s_MS_Search_program_e1be8d0169.jpg" alt="James Little: Can you send spectra to NIST’s MS Search program" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_Can_you_send_spectra_to_NIST_s_MS_Search_program_e1be8d0169.jpg 245w," sizes="100vw" width="1909" height="497"><h4>1) This will open NIST MS Search and load the spectrum you sent.</h4>Note: When you click “Send spectrum to NIST MS program”. The MSP text file is generated and saved to a temporary folder (C:Usrs\&lt;CurrentUser&gt;\AppData\ Local\Temp\SPECTRA.MSP), should you need to access it<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_This_will_open_NIST_MS_Search_and_load_the_spectrum_you_sent_bf27ee181b.jpg" alt="James Little: This will open NIST MS Search and load the spectrum you sent" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_This_will_open_NIST_MS_Search_and_load_the_spectrum_you_sent_bf27ee181b.jpg 245w," sizes="100vw" width="1920" height="1152"><h4>2) Can you process the OpenLab mass spec file in MassHunter?</h4>Yes, you can convert OpenLab CDS data to MassHunter format. You can then analyze the converted data in MassHunter Quant, Qual, and Unknowns Analysis. You cannot open it in MSD ChemStation Data Analysis. There is a conversion tool you can access starting in MassHunter Quant 11.1.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_Can_you_process_the_Open_Lab_mass_spec_file_in_Mass_Hunter_687cc49263.jpg" alt="James Little: Can you process the OpenLab mass spec file in MassHunter" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_Can_you_process_the_Open_Lab_mass_spec_file_in_Mass_Hunter_687cc49263.jpg 245w," sizes="100vw" width="1352" height="790"><h4>3) Can you convert OpenLab to netCDF (AIA) files?</h4>Yes. The AIA export functionality in Post Processing Plugins allows the export in NetCDF format. For example, if you wanted to use NIST’s AMDIS program or Wiley KnowItAll, this is how you can export your data.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_Can_you_convert_Open_Lab_to_net_CDF_AIA_files_5f44626879.jpg" alt="James Little: Can you convert OpenLab to netCDF (AIA) files" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_Can_you_convert_Open_Lab_to_net_CDF_AIA_files_5f44626879.jpg 245w," sizes="100vw" width="1289" height="495"><h4>4) Data File Locations in OpenLab</h4><ul><li>CDS is organized in result sets – files are grouped together based on the sequence they are run with into folders called &lt;MyResultName&gt;.rslt (or &lt;MyResultName&gt;.sirslt for single injections). This *.rslt or *.sirslt folder contains all the data and processing information needed to reconstruct the analysis (acquisition method, processing method, raw data, results, etc.)</li><li>Raw data is stored in *.dx files. Results are stored in *.rx files. Each injection will have one *.dx and one *.rx file.</li><li>The MS data is stored in the same format that MassHunter uses – namely for GCMS single quads there are two binary files which contain the raw data - *.MSPeak.bin and *.MSScan.bin.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_Data_File_Locations_in_Open_Lab_c42ec63450.jpg" alt="James Little: Data File Locations in OpenLab" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_Data_File_Locations_in_Open_Lab_c42ec63450.jpg 245w," sizes="100vw" width="784" height="326"><h4>5) Can library searches be performed with NIST dll and then returned to OpenLab for Display?</h4>Yes, see page 29 in the following <a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/cs/library/usermanuals/public/CDS_Configure_MS_Libraries.pdf">link</a> to Agilent documentation<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_Can_library_searches_be_performed_with_NIST_dll_and_then_returned_to_Open_Lab_for_Display_b95a109ac2.jpg" alt="James Little: Can library searches be performed with NIST dll and then returned to OpenLab for Display" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_Can_library_searches_be_performed_with_NIST_dll_and_then_returned_to_Open_Lab_for_Display_b95a109ac2.jpg 223w," sizes="100vw" width="1191" height="834"><h4>6) What library formats are used with OpenLab?</h4>OpenLab CDS can only use libraries in NIST format – so for users with existing .L (PBM) libraries, we direct them to convert using NIST’s Lib2NIST utility. mslibrary.xml libraries can also be converted, if you first send them to JCAMP format, then use Lib2NIST.Information can also be found in section 5 of the following manual, <a target="_blank" rel="noopener noreferrer" href="https://www.agilent.com/cs/library/usermanuals/public/CDS_Configure_MS_Libraries.pdf">here is the link</a><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_What_library_formats_are_used_with_Open_Lab_5c8a459932.jpg" alt="James Little: What library formats are used with OpenLab" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_What_library_formats_are_used_with_Open_Lab_5c8a459932.jpg 245w," sizes="100vw" width="1148" height="671"><h4>7) How do I add to or create a user library?</h4><ol><li>All libraries used in OpenLab are in NIST format</li><li>Thus, to add a library entry or to create the first entry in a new user library, first send the spectrum to NIST MS Search from OpenLab by using the “Send spectrum to NIST MS program”</li><li>Then the Librarian Tab is selected at bottom of the NIST MS Search Program</li><li>The remaining details are found in my videos with associated handouts on my web page</li><li>EI MS libraries, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/4542">Effective Use of EI Mass Spectral Databases in Unknown Identifications - Part V: Creating and Sharing User EI and MS/MS Libraries</a></li><li>MSMS libraries, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/1367">LC/MS Unknown Identifications Using MSMS Libraries Part VII: Using and Creating Other MSMS Libraries</a></li></ol><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_How_do_I_add_to_or_create_a_user_library_f7c981e18a.jpg" alt="James Little: How do I add to or create a user library" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_How_do_I_add_to_or_create_a_user_library_f7c981e18a.jpg 245w," sizes="100vw" width="874" height="186"><h4>8) Initial Settings for NIST Search V3.0 in EI and MSMS (tandem) Modes</h4><ul><li>There are many settings to setup when first using NIST MS Search</li><li>After setup, user saves as a configuration which makes easy to restore if changed during processing</li><li>EI Quick Start Guide for Settings <a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/wp-content/uploads/2024/12/Library_Settings_EI.pdf">Link</a></li><li>MSMS (tandem) Quick Start Guide for Settings <a target="_blank" rel="noopener noreferrer" href="https://littlemsandsailing.com/wp-content/uploads/2024/11/My-Tips-plus-NIST-Quick-Start-Guide.pdf">Link</a></li></ul><h4>9) Agilent OpenLab Help &amp; Learning</h4><ul><li>Great resource for a large group of topics</li><li><a target="_blank" rel="noopener noreferrer" href="https://openlab.help.agilent.com/">https://openlab.help.agilent.com/</a></li><li>After choosing language, e.g., one can find information on library search</li><li><a target="_blank" rel="noopener noreferrer" href="https://openlab.help.agilent.com/en/index.htm#t=mergedProjects%2FDataAnalysis%2FUseMSlibrarysearch.htm">https://openlab.help.agilent.com/</a></li><li>Easily search for useful topics, e.g., look for information on AIA netCDF file export as shown below on right side of screen</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/James_Little_Agilent_Open_Lab_Help_and_Learning_4f3dece387.jpg" alt="James Little: Agilent OpenLab Help &amp; Learning" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_James_Little_Agilent_Open_Lab_Help_and_Learning_4f3dece387.jpg 243w," sizes="100vw" width="1143" height="732">

Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications

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RECETOX (Research Centre for Toxic Compounds in the Environment) is an independent department of the Faculty of Science of Masaryk University in Brno, which has been established in 1983. RECETOX is focused on the research and education in cross-cutting area of Environment and Health. It addresses interactions among chemicals, environment, and biological systems, including consequences at local, regional, and global levels.

RECETOX - Centrum pro výzkum toxických látek v prostředí

The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography (MDC) Workshop

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

Merck

Mettler-Toledo

Agilent Technologies

GERSTEL

Improvements to Microplastics workflow will be demonstrated. Agilent ftir<blockquote>Presenter: Louis Tisinger, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)Louis (Lou) Tisinger has a Ph.D. in Analytical Chemistry from Miami University in Oxford Ohio, where his graduate research involved the study of ATR imaging and microscope performance in vibrational spectroscopy. Most of his career has been related to pre- and post-sales support of FTIR spectrometers, microscopes, imaging systems, and thermal analytical instruments, focusing on analyzing customer samples, demonstrations, post-sales training, troubleshooting, and R&amp;D.</blockquote>

Agilent Technologies: New Improvements to MP Workflow

New Improvements to MP Workflow

Improvements to Microplastics workflow will be demonstrated. 

Enter the world of automated sample preparation for MOSH/MOAH analysis! In this webinar we will show you the different sample preparation methods for MOSH &amp; MOAH analyses and their automation with the GERSTEL MultiPurpose Sampler. Our experts will explain the necessity of sample preparation as well as the methods - saponification, epoxidation and AlOx purification - required for the different matrices.Highlights of the webinar:<ul><li>Necessity and benefits of sample preparation for MOSH/MOAH analysis</li><li>Detailed insights into workflows for automated sample preparation</li><li>Expert knowledge on selecting the suitable methods for different matrices</li></ul>Register now and automate your MOSH/MOAH sample preparation!<blockquote>Presenter: Isabelle HekerPresenter: Timo Köhler, Ph.D.</blockquote>

GERSTEL: Efficiency boost through automation MOSH/MOAH

Efficiency boost through automation MOSH/MOAH

In this webinar we will show you the different sample preparation methods for MOSH & MOAH analyses and their automation with the GERSTEL MultiPurpose Sampler.

Discover the GERSTEL ChroMOH software, our powerful evaluation software for MOSH/MOAH data, in our informative webinar! See how this software simplifies and accelerates the quantitative analysis of complex MOSH/MOAH chromatograms.Highlights of the webinar:<ul><li>Intuitive workflow for efficient and fast evaluation of complex chromatograms</li><li>Detailed insights into the natural and accurate integration of MOSH/MOAH Humps</li><li>Transparent and customizable reporting</li></ul>Register today and revolutionize your data analysis!

GERSTEL:  Precise results within seconds  The future of MOSH/MOAH data analysis

Precise results within seconds  The future of MOSH/MOAH data analysis

Discover the GERSTEL ChroMOH software, our powerful evaluation software for MOSH/MOAH data, in our informative webinar!

 Precise MOSH/MOAH analysis in seconds

<h4>Eight Webinars and a Roundtable with Experts from Merck&nbsp;</h4>Analytical Excellence Week' is organized to empower professionals in the field of analytical chemistry. Over the course of eight insightful sessions, industry experts will share their knowledge and best practices to streamline your analytical workflows and enhance your efficiency.From understanding quality grades in inorganics and solvents to exploring sustainable practices in the lab, each webinar covers essential topics that will enhance your analytical capabilities. Learn how to optimize your Karl Fischer titration, achieve precision in PFAS testing, and gain troubleshooting tips for LC-MS to effectively address common challenges and improve your laboratory results. The sessions will also address critical aspects of safety and sustainability, ensuring you are well-equipped to handle hazardous chemicals responsibly while making strides toward greener laboratory practices.This is an invaluable opportunity to gain insights that can significantly optimize your analytical processes. Don’t miss your chance to elevate your expertise and contribute to a more efficient and sustainable future in analytical workflows. Each session is specifically designed to address essential topics that directly impact your daily practices, making it relevant for all professionals working in a chemical analysis laboratory.<h3>Day 2: Tuesday, 11 February</h3><h4>Dihydropinene, γ-Valerolactone, and Dimethyl Isosorbide: Bio-Sourced Versatile Green Solvents for Diverse Organic Synthesis</h4>The growing environmental concerns and regulatory restrictions on conventional organic solvents derived from non-renewable sources have spurred the search for greener, sustainable alternatives. This presentation will explore the potential of dihydropinene (DHP), γ-valerolactone (GVL), and dimethyl isosorbide (DMI) as bio-sourced and biodegradable solvents, offering a promising solution to replace toxic and non-renewable solvents. DHP, derived from turpentine oil, is an effective substitute for solvents such as n-hexane, benzene, and dichloromethane, while GVL and DMI are ideal replacements for hazardous solvents such as DMF, NMP, and DMA.These solvents not only perform well in various chemical transformations but also offer significant environmental benefits due to their biodegradability, low toxicity, and recyclability. The presentation will highlight the applications of DHP, GVL, and DMI in green chemistry, showcasing their potential in organic synthesis and industrial processes. It will also discuss their role in advancing sustainable practices, reducing dependency on fossil-based solvents, and promoting safer working environments. By focusing on green solvent solutions, the presentation will emphasize their future potential in scientific research, production, and industrial applications.By attending this webinar, you will learn:<ul><li>Sustainable Solvent Alternatives: How bio-based solvents such as DHP, GVL, and DMI can replace conventional toxic solvents, providing eco-friendly, biodegradable options for chemical processes.</li><li>Environmental and Safety Benefits: The environmental advantages of these solvents, including biodegradability, low toxicity, and recyclability, and how they promote safer and greener practices in research and industry.</li><li>Practical Applications: How these solvents can be effectively used in organic synthesis, industrial processes, and various scientific fields, contributing to more sustainable and efficient chemical solutions.</li></ul>Who should attend: This presentation will benefit those working in pharmaceutical and drug discovery R&amp;D, process development of API, environmental scientists and sustainability experts, industry professionals in chemical engineering and manufacturing, materials science researchers, and students and researchers in green chemistry.<blockquote>Presenter: Saikat Sinha, (R&amp;D Manager, Merck)&nbsp;</blockquote><h4>Enhance Your PFAS Testing: Achieve Precision and Reduce Background Noise with Specialized Consumables</h4>Join this presentation to explore advanced LC-MS/MS methods for determining PFAS analytes at low levels across diverse samples and matrices. Learn how to identify contamination sources, reduce background noise, and improve testing precision with specific recommendations on PFAS-qualified consumables. Discover various LC-MS/MS PFAS testing workflows and strategies to minimize errors, supported by data from both regulated and non-regulated methods.By attending this webinar, you will learn:<ul><li>Detailed insights into different LC-MS/MS PFAS methods</li><li>Techniques to identify and test contamination sources</li><li>Strategies to reduce background noise</li><li>Practical tips and tricks for improved testing</li></ul>Who should attend: This webinar is essential for lab technicians, lab managers, and quality assurance managers involved in developing in-house methods or verifying regulated testing protocols such as EPA Methods 533, 537.1, and 1633.<blockquote>Presenter: Patrik Appelblad, (Fellow and Technical Lead, Analytical Chemistry R&amp;D, Merck)&nbsp;</blockquote>

Merck: Webinar Series & Expert Roundtable

Webinar Series & Expert Roundtable (Day 2)

(Day 2) - Part 1: Dihydropinene, γ-Valerolactone, and Dimethyl Isosorbide: Solvents for Organic Synthesis and Part 2: Enhance Your PFAS Testing

<h4>Eight Webinars and a Roundtable with Experts from Merck</h4>Analytical Excellence Week' is organized to empower professionals in the field of analytical chemistry. Over the course of eight insightful sessions, industry experts will share their knowledge and best practices to streamline your analytical workflows and enhance your efficiency.From understanding quality grades in inorganics and solvents to exploring sustainable practices in the lab, each webinar covers essential topics that will enhance your analytical capabilities. Learn how to optimize your Karl Fischer titration, achieve precision in PFAS testing, and gain troubleshooting tips for LC-MS to effectively address common challenges and improve your laboratory results.The sessions will also address critical aspects of safety and sustainability, ensuring you are well-equipped to handle hazardous chemicals responsibly while making strides toward greener laboratory practices.This is an invaluable opportunity to gain insights that can significantly optimize your analytical processes. Don’t miss your chance to elevate your expertise and contribute to a more efficient and sustainable future in analytical workflows.Each session is specifically designed to address essential topics that directly impact your daily practices, making it relevant for all professionals working in a chemical analysis laboratory.<h3>Day 1: Monday, 10 February</h3><h4>Navigating Quality Grades Part 1: Inorganics and Solvents for Classical Analysis and Research</h4>Join us for an insightful webinar focused on the critical process of selecting the right quality grade for inorganic reagents and solvents used both in analytical and research applications. We will provide an in-depth overview of various quality grades, including ACS grade and EMSURE®, and discuss their specific attributes, including purity, regulatory support, and packaging. Gain valuable insights into the importance of this choice and its impact on the quality of your lab processes and outcomes.By attending this webinar, you will:<ul><li>Understand the significance of choosing the right quality grade for your lab applications</li><li>Explore the available quality grades, including ACS grade and EMSURE®, and their specific attributes</li><li>Recognize the impact of quality grade selection</li><li>Learn best practices for selecting and utilizing the appropriate quality grade for several applications</li></ul>Who should attend:This webinar is designed for professionals involved in laboratory work who seek to enhance their understanding of quality grades for inorganic reagents and solvents. It is particularly relevant for lab technicians, researchers, and managers in analytical labs (like QC, environmental, etc.) method development and research laboratories that are looking to optimize their processes and outcomes.<blockquote>Presenter: Christian Roth (Senior Product Manager Inorganics, Merck)Presenter: Lyra Christianson (Product Manager Solvents, Milwaukee, Wisconsin, USA, an affiliate of Merck)</blockquote><h4>Navigating Quality Grades Part 2: Solvents and Reagents for Chromatography Applications</h4>This second part focuses on the critical process of selecting the right quality grades used in chromatography applications. We provide an in-depth overview of various quality grades, from Suprasolv® solvents for GC to LiChrosolv® solvents for HPLC, in combination with LiChropurTM reagents, and discuss their specific attributes, including purity, regulatory support, and packaging. The topic will be illustrated by typical HPLC and LC-MS applications.By attending this webinar, you will learn:<ul><li>Which grades are suitable for which chromatographic analysis</li><li>What are the specific attributes of the solvents and reagents</li><li>How to combine different quality grades meaningfully</li><li>How to identify and differentiate between various quality grades of reagents and solvents.</li><li>To understand the critical importance of selecting the appropriate quality grade for your specific analytical applications</li></ul>Who should attendLab technicians, lab managers, and quality control-related persons who need to understand how to select the different quality grades for HPLC and LC-MS applications.<blockquote>Presenter: Patric Klein, (Global Product Manager Organic and Inorganics Instrumental Analysis, Merck)Presenter: Fernando Luengo, (Global Product Manager HPLC Solvents, Milwaukee, Wisconsin, USA, an affiliate of Merck)Presenter: Daniel Weibel, (Global Product Manager Solvents, Merck)</blockquote>

Webinar Series & Expert Roundtable (Day 1)

Navigating Quality Grades Part 1: Inorganics and Solvents for Classical Analysis and Research and Part 2: Solvents and Reagents for Chromatography Applications

<h4>Eight Webinars and a Roundtable with Experts from Merck</h4>Analytical Excellence Week' is organized to empower professionals in the field of analytical chemistry. Over the course of eight insightful sessions, industry experts will share their knowledge and best practices to streamline your analytical workflows and enhance your efficiency.From understanding quality grades in inorganics and solvents to exploring sustainable practices in the lab, each webinar covers essential topics that will enhance your analytical capabilities. Learn how to optimize your Karl Fischer titration, achieve precision in PFAS testing, and gain troubleshooting tips for LC-MS to effectively address common challenges and improve your laboratory results.The sessions will also address critical aspects of safety and sustainability, ensuring you are well-equipped to handle hazardous chemicals responsibly while making strides toward greener laboratory practices.This is an invaluable opportunity to gain insights that can significantly optimize your analytical processes. Don’t miss your chance to elevate your expertise and contribute to a more efficient and sustainable future in analytical workflows.Each session is specifically designed to address essential topics that directly impact your daily practices, making it relevant for all professionals working in a chemical analysis laboratory.<h3>Day 3: Wednesday, 12 February</h3><h4>Optimize Your Karl Fischer Titration: Expert Insights for Enhanced Results</h4>With Karl Fischer titration, you can quickly and accurately determine water content in a wide variety of samples. The accuracy of the results depends on a well-defined titration application process. Pre-titration and titer determination are essential for obtaining correct results. The main challenges arise from samples that do not dissolve or that undergo side reactions in standard solvents. Learn the measures you can take to release water from such samples and the preferred methods to use—volumetry or coulometry. Additionally, discover how digital data transfer enables efficient, fast, and secure data integration with your titrator software.By attending this webinar, you will learn:<ul><li>The key steps in the Karl Fischer titration process</li><li>The importance of accurate pre-titration and regular titer determination</li><li>Effective methods for completely releasing water from your samples</li><li>How digital data transfer can streamline and secure your daily data transfer and documentation</li><li>Practical tips for overcoming daily challenges in Karl Fischer Titration</li></ul>Who should attend: This webinar will be especially valuable for individuals involved in developing Karl Fischer titration applications, performing titrations in QC labs or during in-process control, and those responsible for assessing and enhancing processes. This includes lab technicians, lab managers, and quality assurance managers across various segments.<blockquote>Presenter: Bettina Straub-Jubb, (Global Product Manager Analytical Technologies, Merck)</blockquote><h4>Beyond Safety Standards – Best Practices for Safe Handling of Hazardous Chemicals</h4>This webinar illustrates the role of safety in the lab as well as the challenges that can occur while handling hazardous goods in the daily lab work and how to overcome these challenges. Rules and regulations for daily handling of hazardous goods are discussed, and options are shown on how to improve daily processes regarding personal safety. The presentation focuses on the prevention of accidents, emergency help in case of chemical spillages, and safe and reliable cleaning of lab equipment. Join the webinar for an informative overview of safety solutions and tools for maximum safety and reliability in your lab.By attending this webinar, you will learn:<ul><li>Basic safety risks and rules for daily handling of hazardous goods and options for how to improve daily processes regarding personal safety</li><li>Packaging-related safety topics</li><li>Practical guidelines for handling hazardous chemicals in case of spillages</li><li>Lab equipment cleaning know-how for reliable analytical results</li></ul>Who should attend: Staff and head of chemical labs (e.g. quality control, research), as well as safety managers/safety engineers for chemical laboratories.<blockquote>Presenter: Annett Schneider, (Global Product Manager and Lead Expert for Safety Products and Essentials, Merck)&nbsp;</blockquote>

Webinar Series & Expert Roundtable (Day 3)

Part 1: Optimize Your Karl Fischer Titration and Part 2: Beyond Safety Standards – Best Practices for Safe Handling of Hazardous Chemicals

<h4>Eight Webinars and a Roundtable with Experts from Merck</h4>Analytical Excellence Week' is organized to empower professionals in the field of analytical chemistry. Over the course of eight insightful sessions, industry experts will share their knowledge and best practices to streamline your analytical workflows and enhance your efficiency.From understanding quality grades in inorganics and solvents to exploring sustainable practices in the lab, each webinar covers essential topics that will enhance your analytical capabilities. Learn how to optimize your Karl Fischer titration, achieve precision in PFAS testing, and gain troubleshooting tips for LC-MS to effectively address common challenges and improve your laboratory results.The sessions will also address critical aspects of safety and sustainability, ensuring you are well-equipped to handle hazardous chemicals responsibly while making strides toward greener laboratory practices.This is an invaluable opportunity to gain insights that can significantly optimize your analytical processes. Don’t miss your chance to elevate your expertise and contribute to a more efficient and sustainable future in analytical workflows.Each session is specifically designed to address essential topics that directly impact your daily practices, making it relevant for all professionals working in a chemical analysis laboratory.<h3>Day 4: Thursday, 13 February</h3><h4>Greener Solvents - Making Big Moves for More Sustainability in the Lab!</h4>Laboratories consume significantly more energy and water and generate more waste than offices or households. This is more reason for laboratories to tackle sustainability concerns now. This training supports labs to become greener by addressing the class of chemicals that are used in the largest volumes in the lab: solvents! According to the 12 Principles of Green Chemistry, solvents are more sustainable when they are biobased or when they are less dangerous and hazardous.This training highlights several of these greener solvent alternatives and how they can be implemented in the lab. Due to the large volume in which solvents are used, changing to a greener alternative will significantly reduce the carbon footprint of a lab. A further opportunity to reduce the carbon footprint of a lab and to tremendously reduce waste, are returnable containers for solvents, which will be covered in the second part of the training.By attending this webinar, you will learn:<ul><li>The 12 Principles of Green Chemistry</li><li>What greener solvents are and how they can be implemented in your lab</li><li>How returnable containers for solvents reduce the carbon footprint and amount of waste in the lab</li></ul>Who should attend: This webinar will provide valuable insights for everybody who is working with solvents in the lab and would like to become more sustainable. This includes lab technicians, lab managers, and scientists in chemistry and analytical chemistry labs.<blockquote>Presenter: Frank Michel, (Scientific Education &amp; Sustainability, Chemistry Franchise, Merck)Presenter: John Cooper, (Global Product Manager Sustainable Solvents, Milwaukee, Wisconsin, USA, an affiliate of Merck)</blockquote><h4>Tips and Tricks for LC-MS Troubleshooting</h4>LC-MS is an excellent tool for chemical analysis. Moreover, the evolution in HPLC particle technology, HPLC instrument design, and MS detection resulted in improved performance and sensitivity. This raised the bar on requirements for the purity of the solvents and additives in the mobile phase. This training provides valuable tips and tricks on how to get the best performance out of your LC-MS instrument regarding sensitivity and how to limit instrument downtime by different approaches. Typical examples of LC-MS issues, such as ghost peaks or noisy and elevated baselines, and how to prevent them will be presented. Advanced LC-MS solvents and additives for improved LC-MS performance and their proper handling will be discussed in detail.By attending this webinar, you will learn:<ul><li>The importance of the choice of consumables and solvents for LC-MS</li><li>Approaches to improve sensitivity and robustness of LC-MS</li></ul>Who should attend: This webinar will be especially valuable for scientists, lab managers, and lab technicians working with LC-MS in any application area.<blockquote>Presenter: Frank Michel, (Scientific Education &amp; Sustainability, Chemistry Franchise, Merck)</blockquote>

Webinar Series & Expert Roundtable (Day 4)

Part 1: Greener Solvents - Making Big Moves for More Sustainability in the Lab! and Part 2: Tips and Tricks for LC-MS Troubleshooting.

<h4>Eight Webinars and a Roundtable with Experts from Merck</h4>Analytical Excellence Week' is organized to empower professionals in the field of analytical chemistry. Over the course of eight insightful sessions, industry experts will share their knowledge and best practices to streamline your analytical workflows and enhance your efficiency.From understanding quality grades in inorganics and solvents to exploring sustainable practices in the lab, each webinar covers essential topics that will enhance your analytical capabilities. Learn how to optimize your Karl Fischer titration, achieve precision in PFAS testing, and gain troubleshooting tips for LC-MS to effectively address common challenges and improve your laboratory results.The sessions will also address critical aspects of safety and sustainability, ensuring you are well-equipped to handle hazardous chemicals responsibly while making strides toward greener laboratory practices.This is an invaluable opportunity to gain insights that can significantly optimize your analytical processes. Don’t miss your chance to elevate your expertise and contribute to a more efficient and sustainable future in analytical workflows.Each session is specifically designed to address essential topics that directly impact your daily practices, making it relevant for all professionals working in a chemical analysis laboratory.<h3>Day 5: Friday, 14 February</h3><h4>Roundtable Expert Discussion</h4>Our experts will come together to discuss the best practices to streamline your analytical workflows and enhance your efficiency. We will cover some questions asked during the week, as well as answer new questions during the roundtable discussion. &nbsp;<blockquote>Presenter: Ernie Hillier (Independent Pharmaceutical Consultant, EJH Consulting)</blockquote>

Webinar Series & Expert Roundtable (Day 5)

Webinar Series & Expert Roundtable (Day 5) - Roundtable Expert Discussion

Laboratory balance cleaning is extremely important for accurate weighing results and operator safety. It can be challenging but also fast and easy if you know how to do it right.A clean analytical balance or precision balance is the first step toward safe and accurate weighing. Cleaning increases user safety reduces the risk of cross-contamination, and is the most important action to prolong instrument life. Join our free live webinar to find out more about the benefits of and solutions for cleaning your balance.Program:<ul><li>Why cleaning lab equipment is important for safety and weighing accuracy</li><li>The consequences of not cleaning your balances correctly</li><li>How often you should clean your balance</li><li>The detergents that are suitable for balance cleaning</li><li>The balance features that support fast and effortless cleaning</li></ul><blockquote>Presenter: Adriano Guiso (Trainer, METTLER TOLEDO)</blockquote>

Mettler Toledo: Laboratory Balance Cleaning

Laboratory Balance Cleaning

Join our free live webinar to find out more about the benefits of and solutions for cleaning your balance.

Food and environment testing labs face many challenges and are under pressure to maximize efficiency, productivity, and profitability. Customers expect rapid analysis, with testing done using best-in-class instrument and methods that comply with constantly evolving test regulations. Agilent provides instrumentation, software, consumable, services, and support to help you meet your food and environment testing challenges.In this second session we will talk about the analysis of microplastics in the environment and food.<blockquote>Presenter:&nbsp; Dr. Nopparat Vorapalawut (Spectroscopy Solutions Development Manager, Agilent Technologies)Nopparat joined Agilent Technologies in position of Spectroscopy Application Field Service Engineer and is currently Agilent’s Spectroscopy product specialist based in Thailand.She graduated Ph.D. in Analytical Chemistry and having previously worked in post-doctoral researcher in France and join Agilent in 2016.At Agilent, she is supporting in technical sales and requirement from customers.</blockquote>

Agilent Technologies: Optimizing your food environmental testing: Expert tips and insights with atomic and molecular spectroscopy

Molecular Spectroscopy

In this second session we will talk about the analysis of microplastics in the environment and food.