<p><strong>🎤Jessica Whitehouse</strong></p><p><strong>Haloacetic acids (HAAs) are disinfection byproducts formed when chlorine or bromine reacts with organic matter in water—and some are linked to serious health concerns. In this episode of Concentrating on Chromatography, we sit down with Jessica Whitehouse, MSc student at the University of Calgary, to discuss how she developed a GC-MS method to detect and quantify HAAs in real-world water samples.</strong></p><p>During her undergraduate research at Thompson Rivers University, Jessica tackled a major challenge faced by many academic labs: how to analyze regulated environmental contaminants without access to GC-ECD instrumentation. &nbsp;Using dispersive liquid–liquid microextraction, derivatization, and GC-MS, she built a faster, more accessible workflow—and applied it to tap water, swimming pools, and hot tubs.</p><h4><strong>In this conversation, we cover:</strong></h4><ul><li>What haloacetic acids are and why they matter</li><li>Why standard EPA methods can be difficult for smaller or teaching-focused labs</li><li>How GC-MS can be adapted for HAA analysis</li><li>The challenges of derivatization and temperature program optimization</li><li>Unexpected findings in brominated vs. chlorinated HAAs</li><li>Why pool and hot tub water can show surprisingly high HAA levels</li><li>The excitement (and frustration) of first-time method development</li><li>Advice for undergraduate and early-career analytical chemists</li></ul><p>Jessica also shares how this project led directly to her current MSc research on ozone and nanobubble water disinfection, where she’s now expanding into ion chromatography.</p><p>Whether you work in environmental analysis, chromatography, GC-MS, or are just starting your journey in analytical chemistry, this episode offers practical insight into real lab constraints, method development, and the joy of finding your first analyte peak.</p><h3><strong>Video Transcription</strong></h3><h4><span><strong>Introduction</strong></span></h4><p>Haloacetic acids (HAAs) are an important class of disinfectant byproducts formed when organic matter present in water reacts with chemical sanitizers. Because several HAAs are associated with adverse health effects, their determination remains relevant in environmental and public health analysis. This interview highlights the academic pathway and research experience of Jessica, whose undergraduate work focused on the development of a gas chromatography–mass spectrometry (GC-MS) method for the analysis of HAAs in pool and hot tub water.</p><p>Her project emerged from a combination of academic interest in analytical chemistry, practical experience with water testing, and the constraints of instrument availability in an undergraduate research setting. The resulting workflow illustrates how method adaptation, critical problem-solving, and persistence can enable meaningful analytical research even when standardized methods are not directly accessible.</p><h4><span><strong>Academic Background and Entry into Analytical Chemistry</strong></span></h4><p>Jessica completed a Bachelor of Science in Chemistry with a minor in Physics at Thompson Rivers University in British Columbia. Her interest in analytical chemistry developed during her second year of study, when coursework revealed the quantitative and detail-oriented nature of the discipline. This emphasis on numerical interpretation, precision, and method development aligned strongly with her academic strengths and motivated her to pursue analytical research.</p><p>Her specific interest in water chemistry originated even earlier through practical work in a pool and hot tub store, where she became familiar with routine water testing and the chemical factors influencing water quality. This early exposure led naturally into undergraduate research under the supervision of Dr. Sharon Brewer, whose expertise in water analysis provided an ideal foundation for the project.</p><h4><span><strong>Haloacetic Acids as Disinfectant Byproducts</strong></span></h4><p>Haloacetic acids are a subset of disinfectant byproducts generated when sanitizing agents react with natural organic matter in water. In treated recreational water systems such as pools and hot tubs, disinfectants are essential for microbial control, yet they can also lead to formation of unwanted chemical byproducts. Because some HAAs are considered potentially harmful, their occurrence and concentration warrant analytical attention.</p><p>In this study, both chlorinated and brominated HAAs were of interest. Although the tested water systems were primarily sanitized using chlorine-based products, the occurrence of brominated HAAs emerged as a notable and somewhat unexpected finding.</p><h4><span><strong>Analytical Challenges and Method Selection</strong></span></h4><p>A major challenge in the project was the lack of access to the instrumentation required for the standard EPA-based method initially considered for HAA analysis. The available protocol depended on GC-ECD instrumentation, which was not accessible at the university. This limitation required the development of an alternative strategy based on the instruments available locally.</p><p>GC-MS was selected as the most practical analytical platform. To support this approach, Jessica identified a literature source describing a similar method that could be adapted to her research aims. In parallel, dispersive liquid–liquid microextraction was introduced into the workflow as a means of sample preparation, providing valuable methodological experience beyond the standard undergraduate laboratory curriculum.</p><p>This adaptation illustrates a common reality in academic research: analytical methodology is often shaped not only by ideal regulatory procedures, but also by local instrument access, scheduling limitations, and the practical needs of the researcher.</p><h4><span><strong>Need for Derivatization in GC-MS Analysis</strong></span></h4><p>A central analytical issue was that HAAs are inherently nonvolatile, which makes them poorly suited to direct GC analysis. To enable gas chromatographic separation, derivatization was required to convert the analytes into more volatile derivatives with more favorable boiling characteristics.</p><p>In this method, derivatization with octanol was employed. This modification improved volatility and also generated larger fragments, which aided mass spectral interpretation by making the analyte fragmentation patterns easier to distinguish. Thus, derivatization served both chromatographic and mass spectrometric purposes.</p><h4><span><strong>Optimization of the GC Temperature Program</strong></span></h4><p>Considerable effort was devoted to optimization of the GC temperature program. The main difficulty did not arise solely from the analytes themselves, but from the derivatization reagent. Octanol produced a broad and persistent chromatographic feature, including a significant shoulder extending into later retention times. This complicated separation and increased pressure to keep the method sufficiently short for routine sample throughput.</p><p>Among the analytes, monochloroacetic acid proved especially problematic. Because it differed only subtly in structure and produced overlapping behavior relative to the octanol-derived background, its signal was difficult to isolate confidently. Although chlorine-containing fragments could be observed, precise assignment remained challenging. This difficulty underscores how small structural differences and matrix-related interferences can complicate quantitative GC-MS workflows.</p><h4><span><strong>Method Performance and Practical Advantages</strong></span></h4><p>Although the adapted GC-MS method was developed out of necessity, it also provided practical advantages over the more standardized workflow that had initially been considered. In particular, the derivatization step in the adapted approach required only approximately 10 minutes, whereas the more conventional procedure involved a water bath step lasting around two hours. In addition, the adapted workflow offered shorter overall preparation and analysis timing, allowing batches of samples to be prepared and placed on the autosampler within a normal working schedule.</p><p>From a practical research perspective, this translated into substantially improved laboratory efficiency. The ability to complete derivatization quickly and begin automated sample analysis without extensive delays made the workflow more manageable and better suited to the demands of an undergraduate project.</p><h4><span><strong>Unexpected Findings: Brominated HAAs in Chlorine-Sanitized Systems</strong></span></h4><p>One of the more surprising outcomes of the study was the predominance of brominated HAAs, despite the fact that the investigated pools and hot tubs were sanitized using chlorine-based treatments. Four of the systems relied on sodium chloride electrolysis to generate chlorine species, while others used chlorine-containing puck formulations commonly applied in recreational water treatment.</p><p>Given these conditions, higher levels of chlorinated HAAs might have been expected. Instead, the results suggested a greater abundance of brominated HAAs. A plausible explanation is the presence of bromine-containing impurities in commercial pool and hot tub chemicals. Although such impurities may occur at relatively low levels, they can still influence disinfectant byproduct formation. The observation highlights the importance of considering the full chemical composition of treatment products, not merely their primary declared active ingredients.</p><h4><span><strong>Value of Practical Industry Experience</strong></span></h4><p>Jessica’s prior work in the pool and hot tub industry provided an unusually strong contextual advantage for the project. Because the samples originated from store clients, she had access to detailed information about the chemicals used in each system, including safety data sheets and knowledge of treatment timing. This background significantly strengthened interpretation of the analytical results by linking measured byproducts to known product usage patterns.</p><p>Such integration of practical field knowledge with laboratory analysis represents an important strength in applied environmental chemistry, particularly when studying real-world water systems rather than idealized laboratory samples.</p><h4><span><strong>Scientific Development and Early Research Motivation</strong></span></h4><p>An especially valuable element of the project was the role it played in building research confidence. Jessica described the first successful identification of an analyte peak as a memorable turning point, reflecting the emotional significance of early experimental success in scientific training. In analytical chemistry, where method optimization often involves repeated setbacks and ambiguous data, such moments can be critical in sustaining motivation and reinforcing scientific identity.</p><p>This experience also informed her advice to early-stage researchers: unfavorable or unexpected outcomes still constitute valid results. Negative or imperfect findings remain analytically meaningful and contribute to scientific understanding, provided they are interpreted carefully.</p><h4><span><strong>Connection to Current Research</strong></span></h4><p>Jessica is now working at the University of Calgary on a different project focused on ozone and nanobubble disinfection. Although the analytical platform and immediate research questions have changed, the conceptual connection to her earlier work remains clear. Her experience with disinfectant byproducts and water chemistry directly supported her transition into this new role and helped position her as a strong candidate for research in water treatment-related systems.</p><p>She also expressed interest in expanding her analytical expertise through ion chromatography, which will play a role in her current work. This transition reflects the broader development of an environmental analytical chemist whose work continues to center on water quality, disinfection chemistry, and the analytical tools needed to investigate both.</p><h4><span><strong>Public Health Relevance</strong></span></h4><p>A notable practical implication of the project concerns recreational water safety. Jessica emphasized that pool and hot tub water should not be ingested, a recommendation already widely understood in general terms but further reinforced by her findings. In at least one case, HAA concentrations were reported at levels far above the federal drinking water regulation threshold. While such regulations are designed for potable water rather than recreational water, the comparison nevertheless illustrates the extent to which disinfectant byproducts may accumulate in these environments.</p><p>She also noted that several HAAs are classified as probable human carcinogens, with prolonged exposure linked to serious health concerns. Although occasional accidental ingestion is not equivalent to chronic exposure, the findings reinforce the importance of appropriate hygiene, safe water maintenance practices, and awareness of chemical byproduct formation in recreational systems.</p><h4><span><strong>Conclusion</strong></span></h4><p>This research demonstrates how meaningful analytical chemistry can emerge from a combination of scientific curiosity, practical constraints, and strong mentorship. By adapting a GC-MS workflow for the determination of haloacetic acids in pool and hot tub water, Jessica developed a method that was both workable within local instrument limitations and efficient enough to offer practical benefits over more conventional procedures.</p><p>Beyond the analytical results themselves, the project highlights several broader themes: the value of undergraduate research, the importance of flexibility in method development, the benefit of practical contextual knowledge, and the relevance of environmental analytical chemistry to real-world public health questions. It also shows how early research experiences can shape a long-term scientific trajectory, leading from undergraduate investigation to continued work in water chemistry and disinfection science.</p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote><blockquote><h4><strong>Concentrating on Chromatography Podcast</strong></h4><p>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!</p><p>You can find <strong>Concentrating on Chromatography Podcast </strong>in podcast apps:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL"><strong>Spotify</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185"><strong>Apple podcast</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography"><strong>podscan</strong></a></li></ul><p>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos"><strong>YouTube channel</strong></a></p></blockquote>

Detecting Haloacetic Acids in Water with GC-MS

<p><strong>This study presents a one-year assessment of microplastic concentrations in the River Rhine, analyzing samples from three locations and across multiple size fractions using TED-GC/MS. Dominant polymers included polyethylene, polypropylene, polystyrene, styrene–butadiene rubber, and natural rubber.</strong></p><p>Statistical analysis revealed size-dependent distributions, minor seasonal variation, and spatial differences, highlighting the role of sources such as tire abrasion. The findings provide valuable data for environmental monitoring, ecotoxicological research, and regulatory frameworks related to water quality.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsestwater.5c00530"><strong>One Year Observation of Microplastic Concentrations in the River Rhine</strong></a></h4><p>Yosri Wiesner, Paul Eisentraut, and Korinna Altmann*</p><p>ACS EST Water 2026, 6, 2, 639–648</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acsestwater.5c00530">https://doi.org/10.1021/acsestwater.5c00530</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p><strong>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.</strong></p><div><p>As microplastics (MPs) are found all over the world and no comprehensive knowledge is available yet, extensive monitoring campaigns are required to gain a full understanding of their occurrence, transportation and fate. <a href="javascript:void(0);">(1,2)</a> In particular, MP abundance in freshwater systems has still not been sufficiently investigated. <a href="javascript:void(0);">(3,4)</a> Additionally, the question of the toxicological potential of MPs has been the subject of numerous studies for many years, <a href="javascript:void(0);">(5,6)</a> leading to more precise and complex experimental set-ups and results. However, there is still a need for more acurate data on environmental MP concentrations in order to make ecotoxicological tests even more detailed and realistic. The lack of certainty for exposure concentrations in the risk assessment frame of MPs leads to the precautionary principle being applied by politicians and regulators worldwide. Both the EU drinking water directive and the wastewater directive call for monitoring of MPs within the next few years. It is important to establish suitable analytical methods for sampling, sample preparation and detection that must now be fast, robust and fit for purpose in order to obtain representative and valid results depending on mass or particle number. <a href="javascript:void(0);">(7−9)</a></p><p>MPs are solid particles with a size of 1–1000 μm mainly consisting of polymers (ISO/TR 21960, 2020) and can, for example, result from industrial production in the form of small particles that are designed as additives and change the properties of products, or from plastic parts that have been released into the environment. Major sources of MPs today are paints, tires, packaging materials, pellet waste and textiles. <a href="javascript:void(0);">(10−12)</a> These macroplastic products can form MP particles as a result of degradation factors such as photooxidation, hydrolysis and mechanical abrasion. <a href="javascript:void(0);">(13,14)</a></p><p>The River Rhine has its origin in Switzerland and then flows through Liechtenstein, Austria, Germany and France until it discharges into the North Sea in The Netherlands. At 1233 km and a catchment area of about 185&nbsp;000 km<sup>2</sup>, the Rhine is one of the largest river systems in Europe and, due to its expanse, forms the ecological basis for a large number of animal species. Around 30 million people in Germany are supplied with drinking water from the Rhine.</p><p>It is hardly possible to assess the occurrence of MPs if either a limited sampling volume is used or only individual samples are taken. It is therefore essential that different volumes are sampled depending on whether the water to be sampled contains many or few MP particles. It is recommended to sample at least 5 m<sup>3</sup> for drinking water samples and 1 m<sup>3</sup> for surface water, whereas raw wastewater contains so many particles that only a few liters need to be sampled. <a href="javascript:void(0);">(15)</a> Although sampling of these water volumes leads to a representative sample from the analytic point of view, it is questionable, if the result measured is representative for the location. Previous studies have shown that the composition in terms of MP masses in a water body can change at one location with each individual sample independently whether several samples are analyzed in 1 day or spread over several days. <a href="javascript:void(0);">(16)</a> Fractionated filtration and sedimentation boxes as active and passive sampling methods have proven themselves in the sampling of freshwater systems. In active sampling, water is fractionally filtered using a pump and a sieve tower with different mesh sizes. <a href="javascript:void(0);">(17)</a> Passive sampling can be carried out using sedimentation boxes. <a href="javascript:void(0);">(18)</a> In a sedimentation box, the flow velocity of the medium flowing through is reduced by using several baffle plates. Due to the reduced velocity and energy, particles up to a certain size are forced to sediment by the now predominant gravitational force. Such boxes can remain in the water for several weeks and therefore collect a cross-section of the suspended particles including MP over a certain period of time.</p><p>Mass and number-based methods have emerged as suitable detection methods for MPs. <a href="javascript:void(0);">(19)</a> Number-based methods such as μ-Raman, μ-FTIR or LDIR are well advanced to evaluate the polymer identity, particle number concentration and shape, <a href="javascript:void(0);">(20,21)</a> but are still time-consuming in terms of sample preparation. In regulatory approaches or for simulations, usually the MP mass is needed. MP polymer identity and masses can be detected by thermoanalytical methods like pyrolysis-GC/MS (Py-GC/MS) or thermal extraction desorption-GC/MS (TED-GC/MS). Especially TED-GC/MS seems to be suitable for monitoring purses of suspended particulate matter, because there is no need for additional sample preparation others than filtration and homogenization. Up to 50 mg of suspended particulate matter can be directly measured in one run, giving representative subsamples for precise measurements exceeding the limit of quantification. Furthermore, styrene–butadiene rubber (SBR) and natural rubber (NR) as indication for tire wear can be detected in the same sample run next to thermoplastics such as polyethylene (PE), polypropylene (PP), polyethylene terephthalate (PET), polystyrene (PS), polyamide 6 or polyacrylates.</p><p>This work provides a comprehensive data set of MP concentrations of the River Rhine over one year sampling at three different locations starting near the source in Weil via Koblenz and Emmerich. Sampling was done with sedimentation boxes with monthly withdrawal and fractioned filtration of the collected particles afterward. The size fractions 10–50 μm, 50–100 μm and 100–500 μm were provided by the Federal Institute of Hydrology (BfG, Germany) and analyzed at the Federal Institute of Material Research and Testing (BAM, Germany) funded by a national project from the Federal Ministry for the Environment, Nature Conservation, Nuclear Safety and Consumer Protection (BMUV, Germany, 3719 22301 0). Detection was performed with TED-GC/MS in routine mode, proven as a fast and robust detection method. <a href="javascript:void(0);">(2,16,22)</a> Data can be used, for example, for water monitoring or as reference values for future risk assessment scenarios and experiments.</p><h4><strong>2. Materials and Methods</strong></h4><h5><strong>2.2. TED-GC/MS</strong></h5><p>TED-GC/MS is a multistage detection technique combining the thermal sample extraction by thermogravimetric analysis (TGA) with chromatographic separation of the individual decomposition gases and detection by trace analysis with gas chromatography/mass spectrometry (GC/MS). Sample material in 150 μL alumina crucibles was pyrolyzed in a <strong>TGA2 thermobalance</strong> (MettlerToledo, Gieβen, Germany) under a nitrogen flow of 30 mL/min from 200 to 500 °C with a heating rate of 10 K/min. Typical sample intake was between 10 to 50 mg depending on the organic content. The decomposition gases were collected on a solid phase (SorbStar, Envea, Vohenstrauβ, Germany) in the typical polymer decomposition temperature range between 200 and 500 °C via a heated coupling module (240 °C, Gerstel, Mülheim an der Ruhr, Germany). The loaded solid phase was transported to the thermodesorption unit (TDU)-GC/MS by an autosampler (<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=8&amp;search=MultiPurposeSampler+2"><strong>MultiPurposeSampler 2</strong></a> (MPS2), Gerstel, Mühlheim an der Ruhr). The desorption of the decomposition products took place in the TDU (50–200 °C, 5 min isothermal, He gas, Gerstel), the cryofocusing in the cold injection system (−100 °C, Gerstel). Injection was carried out from there by rapid heating (−100–270 °C, 12 K/s) onto the separation column (HP5 ms, 1 mL/min He, 40–300 °C, Agilent, Palo Alto, USA) in the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=7890B"><strong>GC system (7890 B Agilent)</strong></a>. After chromatographic separation, detection was performed in a mass spectrometer (EI, 70 eV, scan-mode, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=5977B"><strong>5977 B, Agilen</strong></a>t).</p><h4><strong>3. Results and Discussion</strong></h4><p>A summary of the identified polymer types and their corresponding mass concentrations per sampling location is provided in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsestwater.5c00530#fig1">Figure 1</a>. All individual results are presented in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acsestwater.5c00530/suppl_file/ew5c00530_si_001.pdf">Table S1</a> of the Supporting Information. With a few exceptions, the polymers PE, PP, PS, SBR and NR were detected. To cope with the large amount of measurement data and to obtain an overview of possible correlations, the data was evaluated using statistical and mathematical algorithms. Only the five polymers named above provide enough input data and are therefore used as the basis for the data analysis. The individual results were sorted according to various aspects that are included in the data set as independent variables:</p><p>(I)&nbsp;&nbsp;&nbsp; Particle size fractions</p><p>(II)&nbsp;&nbsp;&nbsp; Temporal variation</p><p>(III)&nbsp;&nbsp;&nbsp; Spatial variation due to the sampling locations</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_EST_Water_2026_6_2_639_648_Figure_1_Overview_of_sampling_locations_along_the_German_part_of_the_River_Rhine_and_sum_of_identified_median_mass_concentrations_fe570f51b5.jpg" alt="ACS EST Water 2026, 6, 2, 639–648: Figure 1. Overview of sampling locations along the German part of the River Rhine and sum of identified median mass concentrations." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_EST_Water_2026_6_2_639_648_Figure_1_Overview_of_sampling_locations_along_the_German_part_of_the_River_Rhine_and_sum_of_identified_median_mass_concentrations_fe570f51b5.jpg 158w," sizes="100vw" width="1883" height="1860"></p><p>The concentrations of the various polymers in the suspended matter serve as input values. The riverine balancing and material transport based on the total masses (polymer mass in total suspended solids mass) is carried out explicitly and will be published at Umweltbundesamt as part of the project report by the BfG (Ternes, final project report, 2023).</p><h5><strong>3.1. Particle Size Fractions</strong></h5><p>This section describes the possible correlation of the polymer mass concentration with the size of the measured particles regardless of the sampling location. Therefore, the generated samples were sorted by sieving into different size fractions of 10–50, 50–100 and 100–500 μm. The relative mean values of the individual fractions are calculated (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acsestwater.5c00530/suppl_file/ew5c00530_si_001.pdf">Figure S2</a>) to obtain the shares of the different polymer types in the total amount of MP. PE is the dominant polymer in all size fractions with 68–76%, followed by PS (10–15%), SBR (4–13%), PP (2–5%) and NR (2–4%). Obviously, all polymer types are approximately evenly distributed across the size fractions, with SBR being less present in the 100–500 μm fraction.</p><p>In general, it can be determined that PE accounts for the highest proportion of MP. PS makes up the second highest proportion, followed by SBR. Next in line are PP and NR. The polymer findings are in good agreement with previous MP studies of the Rhine. PE, PP and PS in particular are the most frequently detected polymers. <a href="javascript:void(0);">(3)</a> The relative abundance of PE, PP and PS is also relatively similar to Skalska et al., even when the particle number was considered here. <a href="javascript:void(0);">(26)</a> Especially in comparison with the results of Mani et al. significant similarities to the ratios of PE, PP and PS can be found. Data on SBR from tire abrasion in the Rhine is difficult to find in existing studies, as such particles cannot easily be identified using vibrational methods due to the IR absorbing properties and the intense fluorescence of the accompanying soot. However, a comparison with suspended particulate matter samples from the Danube is possible, as here the detection was also carried out using TED-GC/MS. <a href="javascript:void(0);">(2)</a> The relative ratios of PE, PP, PS, SBR and NR are comparable and support the plausibility of the results.</p><p>Total MP mass concentrations are presented in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acsestwater.5c00530/suppl_file/ew5c00530_si_001.pdf">Figure S3</a> for individual polymer types, showing highest mass concentrations in the size fraction 100–500 μm. The median varies from 0.17 to 6.80 μg/mg depending on the polymer type. In absolute terms, the PE mass concentrations are significantly higher than those of all other polymers. PP and PS show a strong mass increase in the 100–500 μm fraction, together with higher uncertainty compared to 10–50 μm and 50–100 μm. With a variation of 0.27–0.32 μg/mg across all particle size fractions, the mass contents of SBR are relatively constant, while NR mass concentration seems to increase more linearly. The high mass concentrations and the strong scattering of the 100–500 μm fractions could be due to the presence or absence of large but few particles. Basically, the larger a particle is, the higher its contribution to the mass concentration. In contrast, the larger a particle is, the lower the probability of an equal distribution in all samples.</p><p>If other regions associated with the Rhine are considered, comparable ratios of mass concentration in the various particle size fractions are found in Rhine floodplains. <a href="javascript:void(0);">(27)</a></p><p>At the beginning of the data analysis, a Principal Component Analysis (PCA) is carried out to identify parameters that have a high influence on the mass content. This analysis identified that the particle size has the greatest influence on the mass concentration (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsestwater.5c00530#fig2">Figure 2</a>). The first principal component (PC 1) was identified as the particle size fraction and explains over 50% of the differences in the data.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_EST_Water_2026_6_2_639_648_Figure_2_PCA_Score_plot_of_mass_concentrations_of_the_different_polymers_be94ae16c4.jpg" alt="ACS EST Water 2026, 6, 2, 639–648: Figure 2. PCA Score plot of mass concentrations of the different polymers." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_EST_Water_2026_6_2_639_648_Figure_2_PCA_Score_plot_of_mass_concentrations_of_the_different_polymers_be94ae16c4.jpg 184w," sizes="100vw" width="747" height="635"></p><h4><strong>4. Conclusion</strong></h4><p>This study demonstrated that long-term sampling of the Rhine is possible and provides plausible results, which is important for future MP monitoring campaigns, as required by the Urban Waste Water Treatment Directive for the EU. Although the MP concentrations in the Rhine are relatively constant, seasonal and downstream differences were observed. In order to confirm these possible trends, further sampling campaigns are needed to identify possible differences on an annual scale. Furthermore, the influences of urban proximity and land use must be examined in greater detail by increasing the number of measuring points. Additional sample sites are needed to identify possible sources of input. This would be particularly important to clarify the PS concentrations, which show a high correlation between the different particle size fractions in almost all seasons and could indicate a possible common source. SBR is the only polymer to show a relatively constant concentration across all particle sizes and seasons, independent of the river course. Since it is a tire component, constant road traffic could be part of the explanation. However, a different particle ratio must be assumed here compared to the other polymers. The fragmentation mechanism and/or another transport mechanism needs to be clarified.</p><p>Although PE constitutes the majority of the total MP concentration, there may be an overestimation due to false positive signals. To exclude or confirm this, further studies must be conducted to analyze the organic components of the riverine suspended matter in detail.</p><p>A comparison with other studies reveals similar occurrences of the same polymer types and in parts also similar seasonal fluctuations and a slight downstream increase. The differentiated presentation of results in polymer type, particle size fraction and range of mass concentrations can provide a valuable basis for more complex and realistic exposure tests for ecotoxicological studies on freshwater organisms. In particular, the large database for SBR as a tire component could be of special interest, as the toxicity of tire particles due to their chemical composition has already been shown in other studies. In studies using FTIR-based detection methods, these values are usually missing due to the high absorbance of the black tire particles.</p></div>

One Year Observation of Microplastic Concentrations in the River Rhine

<p><strong>In the week of April 6, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>5 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><div><div><div><div><div><div><h5><strong>1. Bruker: Advances in AFM for the Characterization of 2D Materials</strong></h5><ul><li>We, 8.4.2026 17:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6054">Registration</a></li></ul><p>Explore how AFM enables comprehensive nanoscale characterization of 2D materials. Learn about structural, electrical, and chemical mapping, AFM-IR, and nanomanipulation for device fabrication.</p><h5><strong>2. Agilent Technologies: Mastering Gas Sampling: Valve Fundamentals to ASTM Ready RGA &amp; TOGA Analysis</strong></h5><ul><li>Th, 9.4.2026 08:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6056">Registration</a></li></ul><p>In this session, learn how to achieve reliable permanent gas analysis, starting from proper valve selection and sampling fundamentals.</p></div></div></div></div></div></div>

Webinars LabRulezGCMS Week 15/2026

Article

Webinars

Video

Scientists

Scientific article

Interview

Science and research

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

CEM Corporation

Agilent Technologies

SelectScience

Shimadzu Corporation

LCTech GmbH

<p><strong>Agilent offers a variety of unique head space systems.  We will discuss the similarities and differences in their capabilities and interface options that make them more adaptable to today’s frequently evolving laboratory.  Included in the presentation will be software options and tips and tricks to help keep you more productive.</strong></p>
<blockquote>
<p><strong>Presenter: Robert Kubas (GC &amp; GC/MS Application Scientist, Agilent Technologies, Inc.)</strong></p>
</blockquote>
<blockquote>
<p>Robert works for Agilent Technologies as a GC and GC/MS Application Scientist. He has 30+ years’ experience in Chromatography as a Chemist, Service Engineer and Application Scientist. He has a BS in Chemistry and a Masters in Analytical Chemistry from Illinois Institute of Technology in Chicago and as well as a graduate work in Synthetic Organic from Loyola University in Chicago.</p>
</blockquote>
<blockquote>
<p>Prior to becoming a Pre-Sales AE, Hui worked as an LCMS application scientist in Agilent’s global market development group where her primary focus was food and environmental market development.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Simon Jones (GC Applications Engineer/Scientist, Agilent Technologies, Inc.)</strong></p>
</blockquote>
<blockquote>
<p>Simon Jones has over 23 years of GC experience. For the last 15 years, he has been with Agilent as a GC applications engineer/scientist based out of the GC column manufacturing facility in Folsom California. In his roles he has assisted with application development, troubleshooting chromatographic issues, and assisting with instrument configurations. Prior to joining Agilent in 2005, he worked in an analytical lab for the power industry, developing and optimizing testing methodologies for insulating fluids and materials in transformers.</p>
</blockquote>


Agilent Technologies: Selecting the Proper Head Space System for Your Analysis and User Tips

Selecting the Proper Head Space System for Your Analysis and User Tips

<p><strong>Agilent cordially invites you for first ever series of A Virtual OpenLabMasterclass -“Know Your OpenLabCDS”</strong></p>
<p>Our objective of this master class series is to get you through entire CDS workflow from basic step to complete data archivals. From this series of 9 sessions, you would get the most out of your OpenLabCDS.</p>
<h5><strong>You will be able to:</strong></h5>
<ul>
<li>Refresh step by step guide on entire software operation workflows.</li>
<li>See live demonstration &amp; use of some of the unique features of OpenLabCDS.</li>
<li>Address queries of your software operations &amp; some tips to make the best use of OpenLab.</li>
</ul>
<h3><strong>OpenLab CDS Peak Integration optimizer – An effective way to perform peak integration</strong></h3>
<p>Peak integration is an important step in data analysis which can affect the quality of your results. In this session, we will talk about creating processing method, integration parameters, Graphical tools to set integration parameters. We will also look into Peak Integrator Optimizer which allows to easily Integrate large number of peaks in any chromatogram thus improving productivity &amp; efficiency.</p>


Agilent Technologies: Know Your OpenLab - A Master Class Series in OpenLab CDS

OpenLab CDS Peak Integration optimizer – An effective way to perform peak integration

In this session, we will talk about creating processing method, integration parameters, Graphical tools to set integration parameters.

OpenLab CDS Peak Integration optimizer

<p><strong>We’re very excited to bring you a 6 part series of webinars that will air on Wednesdays beginning March 23 and concluding April 6.  Each Wednesday there will be a 1 hour webinar from 11:00AM – 12:00PM (EST) and a 1 hour webinar from 3:00PM to 4:00PM (EST) on a range of different applications and topics using the miniGC, miniGAS and miniLC featuring:</strong></p>
<ul>
<li><strong>Dr. Ronda Gras</strong> of Dow Chemical</li>
<li><strong>Prof. Jim Grinias</strong> of Rowan University</li>
<li><strong>Prof. Emanuela Gionfriddo</strong> of The University of Toledo</li>
<li><strong>Todd Griffin</strong> of G2 Analytical</li>
<li><strong>Prof. Nick Snow</strong> of Seton Hall University</li>
<li><strong>Dr. Alicia Stell</strong> of CEM Corporation/Lucidity</li>
</ul>
<p>CEM | Lucidity is pleased to bring together leaders in the field of chromatographic separation to highlight their cutting edge research and share their techniques with the scientific community. Join us each Wednesday to learn about what is new in chromatography and have the opportunity to ask questions after each talk.</p>
<h3><strong>Wed March 23</strong></h3>
<h4><strong>4:00 - 5:00 PM (CET) Simple and Efficient Solutions for Sample Preparation and Analysis</strong></h4>
<p>To achieve efficient analysis for analytes in solid matrices an efficient extraction is first necessary. CEM offers solvent extraction solutions that produce excellent recoveries extracted in less than 10 minutes in one simple automated process. CEM’s extractions solutions can be paired with Lucidity analysis systems, the miniGC and miniLC. The miniGC, a GC-FID, and the mini-LC, an LC-UV, offer ease of use with a small footprint. The systems are so simple that the operator does not need to be a trained chemist, and the small footprints allows the movement of the systems for point of need analysis. Spanning numerous applications in many markets, including food and environmental, CEM sample preparation solutions combined with Lucidity analysis systems allows for accessibility of this type of work to those whom previously considered it impossible. Thus, CEM and Lucidity systems are an excellent option for laboratories seeking a simple solution for extraction and analysis.</p>
<blockquote>
<p><strong>Presenter: Alicia D. Stell, PhD (Product Manager, Organic Solutions Division, CEM Corporation)</strong></p>
</blockquote>
<blockquote>
<p>Dr. Alicia Douglas Stell has worked with CEM for the past 14 years joining after completing her PhD in Analytical Chemistry. Her extensive background in chromatographic analysis and her mechanical expertise have been instrumental in the development of novel systems for sample preparation and analysis. She has traveled the world to present on these novel systems and to identify new markets for this innovative technology.</p>
</blockquote>
<h4><strong>8:00 – 9:00 PM (CET) Detection and Quantification of THC Isomers in Cannabis Infused Edibles</strong></h4>
<p>The popularity of cannabis infused edibles continues to increase due to state medical and recreational cannabis programs. The 2018 Farm Bill has also led to the introduction of hemp infused consumer products. Recently, hemp derived THC isomers, such as delta-8 THC, have been infused into a wide variety of edibles. The complex nature of edible matrices, and chemical similarity in the THC isomers, presents challenges for labs to accurately detect and quantify these cannabinoids. There is a need for cost effective and reliable sample preparation and analysis techniques. Traditional sample preparation techniques, like QuEChERS, are slow and complex. A novel automated solvent extraction method has been used to prepare the edibles infused with THC isomers and a miniature high pressure liquid chromatography system is used to analyze the samples. This presentation will present the automated sample preparation technique and compare results with QuEChERS method. The HPLC method will be presented along with results from the miniature HPLC.</p>
<blockquote>
<p><strong>Presenter: Todd Griffin (CEO and Chief Scientist, Griffin and Griffin Analytical Associates)</strong></p>
</blockquote>
<blockquote>
<p>Todd Griffin is the CEO and Chief Scientist for Griffin and Griffin Analytical Associates. Todd cofounded G2 Analytical with his daughter in 2019. G2 Analytical works at the intersection of science and society to address some of society’s most challenging analysis problems and contribute to a healthier, safer, and more informed community. Todd is also an instructor of chemistry and mathematics at Wingate University. Prior to starting G2 Analytical, Todd was the Director of Research and Engineering at Chemring Detection Systems and Director of Science &amp; Technology at General Dynamics, ATP leading a dynamic organization dedicated to the research, development, manufacturing, and support of threat detection systems for the defense and security industry. Todd was also the Chief Scientist for Naval Surface Warfare Center, Crane Division (NSWC Crane) for Night Vision, Electro Optics, Chemical, Biological, and Explosives Detection. Todd completed his undergraduate degrees in Chemistry and Mathematics at Wingate University and his graduate degree at Indiana University, Bloomington.</p>
</blockquote>


CEM/Lucidity: Wednesday Webinars on Separation Solutions

Wednesday Webinars on Separation Solutions

Topics: 1. Simple and Efficient Solutions for Sample Preparation and Analysis, 2. Detection and Quantification of THC Isomers in Cannabis Infused Edibles.

<p><strong>With the food industry subject to increasing scrutiny, comprehensive testing solutions are required to determine the authenticity and contaminant-free status of food products and to ensure their compliance with safety regulations.</strong></p>
<p>In this SelectScience® roundtable webinar series, we bring together leading experts in the fields of pesticides analysis, mycotoxin testing and food contact materials characterization to discuss the latest trends in these areas and laboratory innovations set to transform the future of food safety testing. This series consists of three panel discussions, starting on Wednesday, March 23rd.</p>
<h4><strong>Webinar 1: Modernizing pesticides testing</strong></h4>
<p>Wednesday, March 23, at 16:00 GMT / 17:00 CET / 12:00 EDT / 09:00 PDT</p>
<h4><strong>Webinar 2: Measuring migration from food contact materials</strong></h4>
<p>Thursday, April 7th, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT</p>
<h4><strong>Webinar 3: Identifying and controlling mycotoxins in livestock and food products</strong></h4>
<p>Tuesday, April 12th at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT</p>
<blockquote>
<p><strong>Presenter: Susanne Ekroth (Chemist, National Food Agency EU)</strong></p>
</blockquote>
<blockquote>
<p>Susanne Ekroth is an analytical chemist at the Swedish National Food Agency. She graduated from Uppsala University and has been working at the Swedish National Food Agency for 27 years as a pesticide expert. During this time, she has developed skills in advanced technology, including GC-MS/MS, LC-MS/MS and LC-HRMS and is one of the founders of the multi residue method SweEt. Besides pesticides, she also works with food contact materials and toxins in water. </p>
</blockquote>
<blockquote>
<p>In recent years, Susanne has focused on HRMS techniques and the possibility to replace the LC-triple quadrupoles with LC-MS Orbitrap and simultaneously screen for new and unwanted compounds in food matrices. This work is presented as an application note and webinar as well as in Food Safety Magazine.</p>
</blockquote>
<blockquote>
<p>Susanne is a member of the Scientific Organizing Committee for EPRW (European Pesticide Residue Workshop) and IUPAC (Pesticide Congress, Food Quality and Safety). She has given presentations about her work on the SweEt multiresidue method on several occasions, for example at the Nordic-, European- and Latin American Pesticide Residue Workshop, RAFA and Fresenius.</p>
</blockquote>
<blockquote>
<p>Climate change and adaptation have become one of the world&#39;s most important issues and have in recent years become increasingly integrated into the authorities&#39; work. How it can affect lab work and the planning of the official controls are some of the issues that Susanne has been working on in recent years. Working with climate and vulnerability analyses and action plans is under governmental regulation, but it also enables us to be prepared for new substances and new types of food in our screening methods. This type of methodology is very familiar to the pesticide community and future adaptions should work very well. Susanne will present some of the upcoming needs due to climate change.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Steven Lehotay (Lead Scientist, USDA-ARS)</strong></p>
</blockquote>
<blockquote>
<p>Steven J. Lehotay is a Lead Scientist with the USDA Agricultural Research Service at the Eastern Regional Research Center in Wyndmoor, Pennsylvania. Since 1992, he has conducted scientific investigations and method development research involving improvement in the analysis of pesticides, veterinary drugs, and other contaminants in food and environmental samples. He is the co-inventor of the “quick, easy, cheap, effective, rugged, and safe” (QuEChERS) sample preparation approach. He has been awarded with numerous honors, including the AOAC International Harvey W. Wiley Award, and according to the Stanford c-score metric, he resides among the top 0.19% of published analytical chemists.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Dr. Jim Garvey (Head of Food Chemistry, Department of Agriculture, Food and the Marine, Ireland)</strong></p>
</blockquote>
<blockquote>
<p>Dr. Jim Garvey graduated from The National University of Ireland (Galway) in 1988 with a Ph.D. in Organic Chemistry. After seven years in the pharmaceutical industry as a Research Chemist, he became the process development manager in a company producing high purity solvents for GC, HPLC, and MS. He joined the Pesticide Control Laboratory in 1999 and led the laboratory through many changes -- from the introduction of mass spectrometry techniques through various phases culminating in the implementation of HRMS techniques. He led the laboratory through the 2008 dioxin crisis. Since then he has overseen many phases of laboratory development and is currently managing the introduction of HRAM technology to the residues laboratory. In October 2019, he was appointed Head of Food Chemistry at the Department of Agriculture, Food and the Marine. As well as pesticides, the Food Chemistry division covers veterinary drugs, compositional analysis of dairy products, contaminants and elemental analysis. The objective of the new division is to build a centre of excellence for food chemistry within the Department of Agriculture Food and the Marine.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Jana Hajšlová (Head of the Department of Food Analysis and Nutrition, UCT Prague)</strong></p>
</blockquote>
<blockquote>
<p>Professor Jana Hajšlová is Head of the Department of Food Chemistry and Analysis at the Institute of Chemical Technology, Prague. Since 2000, she has been Head of Accredited Laboratory (ISO 17025) focusing on the analysis of food and environmental contaminants, toxicants and biologically active compounds.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Dr. Yelena Sapozhnikova (Research Chemist, USDA-ARS)</strong></p>
</blockquote>
<blockquote>
<p>Dr. Yelena Sapozhnikova is a Research Chemist at the Agricultural Research Service, United States Department of Agriculture (USDA) in Wyndmoor, PA, USA. Her research focuses on the development of new methods for the residual analysis of chemical contaminants, including pesticides, environmental and emerging contaminants, food packaging chemicals using gas and liquid chromatography with mass spectrometry. Dr. Sapozhnikova has over 20 years of experience in the analysis of chemical contaminants in food and environmental samples.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Cristina Nerín (Professor of Analytical Chemistry, University of Zaragoza)</strong></p>
</blockquote>
<blockquote>
<p>Dr. Cristina Nerín is Professor of Analytical Chemistry at the University of Zaragoza, Spain. She is the Director of the Research Group GUIA at the University of Zaragoza and was Director of the Master in Environmental Engineering program from 1990 to 2012. Dr. Nerín is an author of more than 320 scientific publications. Dr. Nerín is also Principal Investigator of more than 200 research projects and an inventor in eight international Patents related to packaging, all in commercial applications. Dr. Nerín has received six research awards, participated in more than 140 international conferences, and instructed courses in Europe, Asia and South-America. Dr. Nerín is on the organizing committee and Chair of several international symposia.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Dwayne Shrunk (Laboratory Manger of Analytical Chemistry Services, Veterinary Diagnostic Laboratory (VDL) at Iowa State University)</strong></p>
</blockquote>
<blockquote>
<p>Dwayne is an accomplished analytical chemist with over 25 years of laboratory experience both as an operator and manager. While supporting research and collaborative partnerships, he is well versed in method development and validation, QA/QC, and lab information management. VDL is recognized as national leader in protecting animal and human health, Wayne’s leadership at one of the full-service laboratories at the VDL process upwards of 100,000 cases each year and conduct more than a million tests annually. As a fully accredited facility by the American Association of Veterinary Laboratory Diagnosticians, the VDL provides quality diagnostic services for animal species, including necropsy, bacteriology, serology, histopathology, virology, parasitology, molecular diagnostics, and toxicology as well as offering analytical services, where understanding the impact natural toxins contribute to the ongoing health of animals is important.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Tim Stratton (Manager of Library Technologies, Thermo Fisher Scientific)</strong></p>
</blockquote>
<blockquote>
<p>Graduate of the University of Minnesota.  Started my career as an analyst in pharma working in regulated analysis, quality control, method validation, etc. for many years with Solvay Pharmaceuticals.  Migrated into pharma research when I moved to Abbott Laboratories working in drug metabolism and pharmacokinetics in all aspects from early high throughput screening to post market phase 4 studies.  My work in research extended for almost 10 years and included working for both large and small pharma companies.  My specific area of focus was structure elucidation and fragmentation interpretation and it’s still an area I really enjoy.  I joined Thermo Fisher almost ten years ago working in the Pharma vertical marketing group, mainly because they promised I could play with the latest toys before they were available.  Since then I’ve been involved in hardware and software testing and development as well as working directly with customers for support and to better understand their needs.  The past few years I’ve transitioned to focus more on the construction of high resolution accurate mass MS/MS and MSn spectral libraries to help with identification of unknowns across all areas of research and this continues to be the main area of focus for me.</p>
</blockquote>


SelectScience: Emerging trends and future directions in food testing

Modernizing pesticides testing (Emerging trends and future directions in food testing)

In this webinar series, we bring together leading experts in the fields of pesticides analysis, mycotoxin testing and food contact materials characterization.

Modernizing pesticides testing

<p><strong>Organizations are often at different points in their digital transformation journey. Data integrity is a critical consideration which typically requires some element of digital transformation to achieve. Ensuring data is accurate, consistent and secure throughout all laboratory processes can increase efficiencies as well as productivity.</strong></p>
<p>As technological advancements are made and the use of electronic data rises, it is imperative that organizations understand the value of data integrity and how to achieve it. A recent report by the National Academies discusses technical challenges and regulatory issues around innovations in pharmaceutical manufacturing and provides recommendations to the industry and related organizations on how to facilitate the adoption of innovative technologies.</p>
<p>Powerful data management is critical in a system that is reliant upon advanced process control and automation, as well as artificial intelligence (AI) and machine learning. A complete, integrated laboratory software system provides streamlined processes and drives data integrity to advance organizations toward a Pharma 4.0 strategy.</p>
<p>In this webinar, we will explore why organizations cannot continue to advance with only technology and must also understand the evolution of data integrity.</p>
<h3><strong>Key learning objectives</strong></h3>
<ul>
<li>Why manufacturing innovation is critical to maintaining a robust global supply chain</li>
<li>The importance of data integrity in achieving Pharma 4.0</li>
<li>How to overcome technical challenges to innovation in pharmaceutical manufacturing</li>
<li>Digital transformation insights from a world-leading CDMO.</li>
</ul>
<h3><strong>Who should attend?</strong></h3>
<ul>
<li>Laboratory directors, supervisors and managers</li>
<li>Scientists, senior scientists or research scientists</li>
<li>Data analytics manager</li>
<li>LIMS administrator</li>
<li>Informatics managers, director, supervisor or engineer</li>
</ul>
<blockquote>
<p><strong>Presenter: Nicola Gardner (Sr. Manager, Product Marketing – Digital Solutions, Thermo Fisher Scientific)</strong></p>
</blockquote>
<blockquote>
<p>As Senior Manager of Product Marketing for the Digital Solutions business at Thermo Fisher Scientific, Nicola describes to customers how they can apply laboratory software to move towards a smarter lab and digitally transform their business. A masters in analytical chemistry and a wealth of laboratory experience provides Nicola with a solid understanding of process, data and connectivity challenges. Nicola helps to drive discussion around technology adoption to inform businesses on their digital transformation journey and to enable scientists to spend more time focusing on science.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Ellen Simms (Editorial Assistant, Selectscience)</strong></p>
</blockquote>
<blockquote>
<p>Ellen studied biological sciences at the University of the West of England, UK, before completing a master&#39;s in epidemiology from the University of Bristol. As a member of the Editorial team, she now plays an integral role in shaping the content on SelectScience.</p>
</blockquote>


SelectScience: Driving data integrity to achieve Pharma 4.0

Driving data integrity to achieve Pharma 4.0

In this webinar, we will explore why organizations cannot continue to advance with only technology and must also understand the evolution of data integrity.

<p><strong>With the increasing complexity of the global food supply chain, quality control has become significantly challenging, thus putting food safety in the spotlight. As it becomes ever more crucial to perform efficient quality control, automated solutions have garnered broad interest for they can provide a cost-effective way to obtain robust data with a fast turnaround time.</strong></p>
<p>In this webinar, discover the capabilities when analytical testing meets innovation – learn how Shimadzu drives automation in food analysis, such as Auto-QuEChERS cleanup workflow to analyze residual pesticides in food. There will also be guest speakers sharing more on the latest trends in automation in food analysis.</p>
<h3><strong>Learning Objectives:</strong></h3>
<ul>
<li>Trends of automation in food safety and quality analysis Importance of Compliance and Regulations for Pharmaceutical Industry</li>
<li>Axel Semrau provides many automated workflows such as PAH, FAME, and Sterol analysis</li>
<li>The reliable PAL3 platform is customizable, for instance for the automated QuEChERS cleanup workflow</li>
<li>Shimadzu hardware and software fully support automated workflows</li>
</ul>
<blockquote>
<p><strong>Presenter: Mr. Malte Hübschen (Application Specialist, Axel Semrau GmbH &amp; Co. KG)</strong></p>
</blockquote>
<blockquote>
<p>Malte is an Application Specialist for GCMS and LC-GC at Axel Semrau, Germany. He has obtained his Master of Science from the University of Münster, and has garnered more than 4 years of experience working on food-related contaminant analyses. </p>
</blockquote>
<blockquote>
<p><strong>Presenter: Ms. Chong Chiew Mei (Application Specialist, CTC Analytics)</strong></p>
</blockquote>
<blockquote>
<p>Chiew Mei graduated from the National University of Singapore, and started her career as a GCMS application specialist. Currently, she works in the CTC Analytics&#39; Singapore laboratory to develop fully automated sample preparation workflows, including the micro-Solid Phase Extraction and online derivatization.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Chua Chun Kiang (Senior Application Chemist, Shimadzu (Asia Pacific) Pte Ltd)</strong></p>
</blockquote>
<blockquote>
<p>Dr Chua is a scientist with experience working in the academia, startup, and MNCs. He has diverse experience in the MS, GC/LC, nanomaterials, electrochemistry, and organic chemistry. He likes putting his knowledge into good use as a content marketer, by helping to simplify and dispersing scientific information to the general audiences.</p>
</blockquote>


Shimadzu Corporation: For the Love of Food! Enabling Automation in Food Analysis

For the Love of Food! Enabling Automation in Food Analysis

Learn how Shimadzu drives automation in food analysis, such as Auto-QuEChERS cleanup workflow to analyze residual pesticides in food.

<p><strong>In the forensics field, it is important that you get the most accurate results in the shortest time, and often with the smallest sample so that you can preserve the remaining amount for further tests.  This calls for instrumentation and equipment that is automated, fast and has superior sensitivity. Shimadzu’s analytical tools do not only meet these requirements seamlessly, thereby giving you the confidence to analyse complex forensic samples but also enable your forensic toxicology laboratory to solve your most pressing analytical challenges, regardless of sample type.</strong></p>
<p>Shimadzu products cover anything from sample preparation to screening, identification and confirmation across a wide variety of forensic applications, ranging from drugs of abuse screening and confirmation, measuring heavy metals and toxins in blood and urine samples, sports doping analysis, trace evidence analysis, and more. In addition, our wide range of instrumentation can be used with a variety of sample types, such as whole blood, urine, plasma, oral fluids, postmortem, tissues, etc.</p>
<p>Tune in to this webinar to learn more about Shimadzu solutions for forensic analysis. </p>
<blockquote>
<p><strong>Presenter: Shailesh Damale (Deputy Manager- Application Support, Shimadzu Middle East &amp; Africa)</strong></p>
</blockquote>


ShimadzuAn Introduction to Shimadzu’s Forensic Solutions

An Introduction to Shimadzu’s Forensic Solutions

Tune in to this webinar to learn more about Shimadzu solutions for forensic analysis. 

<p><strong>The second Pharma Virtual Symposium offers you innovative solutions that address the challenges you face day to day in your lab. Visit the virtual booths to explore workflow &amp; compliance solutions. Explore “Tomorrow’s technologies for today” to improve efficiency, productivity &amp; reduce the compliance risks.</strong></p>
<h5><strong>The symposium will be following these two tracks:</strong></h5>
<ul>
<li>Day 1- Pharmaceutical Workflow For Development To QC</li>
<li>Day 2 - Pharmaceutical Workflow for Impurities</li>
</ul>
<p>Come and explore the world of pharmaceutical solutions which have been developed keeping your daily problems in mind.</p>
<h5><strong>What’s inside the Pharma Virtual Symposium?</strong></h5>
<ul>
<li>Live Webinars from Agilent Experts</li>
<li>Virtual Exhibition with detailed Booths and Application Notes</li>
<li>Live Chat with Experts from your local region</li>
<li>Comprehensive Resource Centre with relevant collaterals for the Pharma Market</li>
<li>Demo Lab with videos about how our Instruments work</li>
</ul>
<p>Join this Symposium and feel free to get involved, ask questions, make suggestions and be a part of the community.</p>
<h3><strong>Day 1 -Pharmaceutical Workflow For Development To QC</strong></h3>
<h5><strong>10:15 a.m. (IST) Lifecycle Management and QbD–An Analytical Perspective</strong></h5>
<ul>
<li>Kuldeep Sharma (Business Development Manager –Pharmaceutical)</li>
<li>Sreelakshmy Menon (Application Specialist –LCAgilent Technologies)</li>
</ul>
<h5><strong>11:15 a.m. (IST) One Instrument Multiple Possibilities: Cary 3500 Uv-vis With OpenlabECM Network Connectivity</strong></h5>
<ul>
<li>Shubham Sengupta (Product Specialist –Spectroscopy, Agilent Technologies)</li>
</ul>
<h5><strong>12:00 p.m. (IST) High Throughput Raman Spectroscopy from Raw Material Testing to Finished Product Analysis</strong></h5>
<ul>
<li>Shubham Sengupta (Product Specialist –Spectroscopy, Agilent Technologies)</li>
</ul>
<h5><strong>02:00 p.m. (IST) An Integrated Laboratory Informatics System for Greater Efficiency and Data Integrity</strong></h5>
<ul>
<li>Amit Ghate (Application Specialist –Lab Informatics, Agilent Technologies)</li>
</ul>
<h5><strong>03:00 p.m. (IST) A Guide to Updating HPLC Compendial Methods in Pharmaceutical Analysis</strong></h5>
<ul>
<li>Sunil Lakhmapure (Technical Support Specialist -Chemistries &amp; Supplies Division, Agilent Technologies)</li>
</ul>
<h5><strong>04:00 p.m. (IST) Compliance And CSV Solutions For Organizations To Comply With The Current Regulatory Requirements</strong></h5>
<ul>
<li>Sridhar Atmakuri (Sales Development Manager –Compliance Specialist, Agilent Technologies)</li>
</ul>


Agilent Technologies: Agilent Pharma Virtual Symposium 2022

Agilent Pharma Virtual Symposium 2022 - Day 1 - Pharmaceutical Workflow For Development To QC

Come and explore the world of pharmaceutical solutions which have been developed keeping your daily problems in mind.

Pharmaceutical Workflow For Development To QC

<p><strong>The second Pharma Virtual Symposium offers you innovative solutions that address the challenges you face day to day in your lab. Visit the virtual booths to explore workflow &amp; compliance solutions. Explore “Tomorrow’s technologies for today” to improve efficiency, productivity &amp; reduce the compliance risks.</strong></p>
<h5><strong>The symposium will be following these two tracks:</strong></h5>
<ul>
<li>Day 1- Pharmaceutical Workflow For Development To QC</li>
<li>Day 2 - Pharmaceutical Workflow for Impurities</li>
</ul>
<p>Come and explore the world of pharmaceutical solutions which have been developed keeping your daily problems in mind.</p>
<h5><strong>What’s inside the Pharma Virtual Symposium?</strong></h5>
<ul>
<li>Live Webinars from Agilent Experts</li>
<li>Virtual Exhibition with detailed Booths and Application Notes</li>
<li>Live Chat with Experts from your local region</li>
<li>Comprehensive Resource Centre with relevant collaterals for the Pharma Market</li>
<li>Demo Lab with videos about how our Instruments work</li>
</ul>
<p>Join this Symposium and feel free to get involved, ask questions, make suggestions and be a part of the community.</p>
<h3><strong>Day 2 - Pharmaceutical Workflow for Impurities</strong></h3>
<h5><strong>10:30 a.m. (IST) Impurity Profiling and Handling Regulatory Challenges</strong></h5>
<ul>
<li>Paramjeet Khandpur (Application Engineer – LPSD, Agilent Technologies)</li>
</ul>
<h5><strong>11:30 a.m. (IST) Extractable and Leachable Analysis: Screening &amp; Relative Quantitation Workflows using High Resolution Accurate Mass LC-MS/MS</strong></h5>
<ul>
<li>Prasanth Joseph (Application Engineer – LC/MS, Agilent Technologies)</li>
</ul>
<h5><strong>02:00 p.m. (IST) Trace Level Quantification of Mutagenic Azido Impurities, NDSRI and Nitrosamine Impurities in Drug Substances and Products using LC-MS/MS</strong></h5>
<ul>
<li>Kartheek Srinivas (Application Engineer – LC/MS , Agilent Technologies)</li>
</ul>
<h5><strong>03:00 p.m. (IST) Extractable and Leachable Analysis: Screening &amp; Relative Quantitation Workflows using GCMS</strong></h5>
<ul>
<li>Soma Dasgupta (Application Engineer – GC/MS, Agilent Technologies)</li>
</ul>
<h5><strong>04:00 p.m. (IST) Streamline your Extractable and Leachable Analysis using Agilent high Sensitivity ICPMS</strong></h5>
<ul>
<li>Dr. Vinay Jain (COE Manager; Application Engineer –Spectroscopy, Agilent Technologies)</li>
</ul>


Agilent Pharma Virtual Symposium 2022 - Day 2 - Pharmaceutical Workflow for Impurities

Pharmaceutical Workflow for Impurities

<p><strong>LCTech GmbH invites you to a Zoom meeting. Be there and let Angelika Köpf and our mycotoxin experts Dr. Frederik Wuppermann explain the advantages of SMART columns to you. In addition, the application with our automation FREESTYLE ThermELUTE™ will be demonstrated.</strong></p>
<p>During this webinar we will show you the manual use of the SMART Columns and the automated processing on our FREEESTYLE ThermELUTE™. You can ask your questions directly to our mycotoxin expert Dr. Frederik Wuppermann during this opportunity.</p>
<p><strong>We will gladly accept your registration via email to news@lctech.de.</strong></p>
<blockquote>
<p><strong>Presenter: Angelika Köpf (Head of Sales at LCTech GmbH)</strong></p>
</blockquote>
<blockquote>
<p><strong>Presenter: Frederik Wuppermann (Product Manager LC - Application at LCTech GmbH)</strong></p>
</blockquote>


LCTech: Getting to know LCTech's mycotoxin SMART columns

Getting to know LCTech's mycotoxin SMART columns

LCTech invites you to the LIVE-DEMO mycotoxin SMART Columns. In addition, the application with our automation FREESTYLE ThermELUTE will be demonstrated.