In this technical tip from Phenomenex, the topic of gas chromatography (GC) column trimming is addressed from a troubleshooting perspective. The key question explored is whether trimming a GC column is necessary and how it impacts chromatographic performance.<h3>Why Trim a GC Column?</h3>Column trimming is primarily used to restore chromatographic performance by removing damaged or contaminated sections, typically located at the column inlet.<h5>1. Baseline Bleed, Noise, Ghost Peaks, Poor Peak Shape</h5><ul><li>Cause: Column contamination</li><li>Removing the contaminated stationary phase at the column entrance helps restore performance.</li></ul><h5>2. Elevated Baseline (Especially at High Temperature)</h5><ul><li>Cause: Column bleed</li><li>Degradation of the stationary phase due to oxygen exposure or thermal damage leads to increased baseline.</li></ul><h5>3. Ghost Peaks (Peaks Without Injection)</h5><ul><li>Cause: Residual sample or contamination</li><li>Compounds trapped at the beginning of the column can appear as peaks even when no sample is injected.</li></ul><h5>4. Peak Tailing (Asymmetrical Peaks)</h5><ul><li>Cause: Damaged or contaminated column sections</li><li>These issues result in adsorption effects or poor flow dynamics.</li></ul><h5>5. Retention Time Shifts</h5><ul><li>Cause: Contamination or damage near the inlet</li><li>Although trimming slightly changes retention time, it can correct shifts caused by inlet-side issues.</li></ul><h5>6. Baseline Noise and Spikes</h5><ul><li>Cause: Particulate matter or degraded stationary phase</li><li>These can lead to detector instability and random signal fluctuations.</li></ul><h5>7. Baseline Drift or Wander</h5><ul><li>Cause: Contamination or oxidized column sections</li><li>Removing these regions stabilizes the baseline.</li></ul><h5>8. Loss of Resolution or Sensitivity</h5><ul><li>Cause: General column degradation</li><li>Trimming removes the most exposed and damaged portions, effectively rejuvenating column performance.</li></ul><h3>How to Trim a GC Column</h3>A capillary GC column consists of:<ul><li>Polyimide outer coating (protective layer)</li><li>Fused silica tubing (fragile but flexible core)</li></ul><h3>Step-by-Step Procedure</h3><h5>1. Scoring the Column</h5><ul><li>Use a ceramic wafer</li><li>Hold it at an inclined angle</li><li>Score the polyimide coating perpendicular to the column</li></ul><h5>2. Breaking the Column</h5><ul><li>Perform a quick, decisive flick</li><li>This ensures a clean, square cut</li></ul><h5>3. Inspecting the Cut</h5>After trimming, visually inspect the column end.<h3>Examples of Column Cuts</h3><h4>Good Cut</h4><ul><li>Clean, square end</li><li>Ensures proper sealing and connection</li></ul><h5>Bad Cuts</h5><ul><li>Slight Irregularity<ul><li>Small imperfection at the edge</li><li>Can cause leaks and active sites</li></ul></li><li>Poor / Rough Cuts<ul><li>Uneven or jagged edges</li><li>Lead to:<ul><li>Poor connections</li><li>Active sites</li><li>Peak tailing</li></ul></li></ul></li></ul><h2>Conclusion</h2>Trimming a GC column is a simple yet effective troubleshooting step. By removing contaminated or damaged sections—especially near the inlet—it can resolve a wide range of chromatographic issues, including baseline instability, ghost peaks, and loss of performance.Proper cutting technique is essential to avoid introducing new problems such as leaks or active sites.

Trimming a GC Column: Purpose, Symptoms, and Proper Technique

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 30th March 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies, Thermo Fisher Scientific, brochure by Shimadzu and presentation by MDCW / LECO!<h3>1. Agilent Technologies: Extraction and Analysis of Pesticides from Water by Solid Phase Extraction and GC/MS</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_extraction_analysis_pesticides_water_gcms_5994_8996en_agilent_28fc35d0e7.pdf">Full PDF for download</a></li></ul>Drinking water is defined as water intended for human consumption obtained from different sources. Several guidelines/regulations exist for ensuring that undesirable substances such as pesticides are not present in excessive amounts that may be harmful to human health. These regulations ensure that water intended for human consumption can be consumed safely. In India, the Bureau of Indian Standards (BIS) has set regulatory limits for residual pesticides in drinking water (IS 10500)1 , packaged drinking water (IS 14543)2 , and natural mineral water (IS 13428).3 A total of 26 pesticides are regulated by BIS standards, of which four compounds (monocrotophos, phorate, 2,4-D, and isoproturon) are more suitable for analysis by liquid chromatography.&nbsp;EPA Method 525.2 is a general-purpose method for determination of organic compounds in finished drinking water or water from any source or treatment stage.4 This method is applicable to a range of organic compounds that are partitioned from the water sample onto a C18 organic phase packed in a disk or cartridge. The organic compounds are then eluted using a suitable eluent, concentrated, and analyzed by GC/MS.&nbsp;This application note describes the use of EPA Method 525.2 for extraction of pesticide residues at trace levels in water using solid-phase extraction (Agilent Bond Elut C18: Straight barrel cartridges, p/n 12102118) and analysis using Agilent 8890-5977 GC/MS.&nbsp;Excellent linearity with R2 &gt; 0.995 was obtained for all pesticides considered for the study. Recoveries were obtained in the range of 80–120% with associated RSDs &lt; 15% at 0.005–0.080 ng/mL level of fortification.<h4>Experimental</h4><h5>Instrument parameters</h5><ul><li>GC: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=8890">Agilent 8890</a></li><li>Column: Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=J%26W+HP-5ms">J&amp;W HP-5ms</a> UI 30 m × 0.25 mm, 0.25 μm&nbsp;</li><li>Carrier Gas: Helium, constant flow, 1.2 mL/min&nbsp;</li><li>Inlet: Agilent Multimode Inlet (MMI)</li><li>MS: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=5977">5977 GC/MS</a></li></ul><h4>Conclusion&nbsp;</h4>A simple, easy, and efficient method based on EPA 525.2 was implemented for the determination of 22 pesticides in water. The method demonstrated good sensitivity, precision, and accuracy, and allows for rapid analysis. The results demonstrate that pesticide residues can be detected below the current maximum residue levels (MRL) required by the BIS specifications. Acceptable recoveries and precision were obtained at concentrations as low as 5 ng/L for all pesticides. The method is ideally suited for use in a regulatory laboratory for the determination of pesticides in surface, drinking, and packaged drinking water.<h3>2. MDCW / LECO: Exploring PFAS in Consumer Goods Using GCxGC and High-Resolution Mass Spectrometry</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_3_Alonso_6f61e3ea43.pdf">Full PDF for download</a></li></ul>Per- and polyfluoroalkyl substances (PFAS) are widely used in consumer and industrial products due to their unique physicochemical properties, but their persistence and potential health risks have made their detection increasingly important. This study focuses on developing an untargeted analytical approach for screening PFAS and related compounds in consumer goods using advanced chromatographic and mass spectrometric techniques.The analytical workflow combines gas chromatography with time-of-flight mass spectrometry (GC-TOFMS) and comprehensive two-dimensional gas chromatography coupled with high-resolution TOFMS (GC×GC-HRTOFMS), using systems such as the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1097">LECO Pegasus® BTX </a>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/38">Pegasus® HRT+</a> platforms. Sample introduction is performed via thermal desorption or pyrolysis, enabling analysis of both volatile and complex matrices. High-resolution MS provides accurate mass measurements and elemental composition, which are essential for identifying unknown compounds and reducing matrix interferences.In the first case study, anti-fog solutions were analyzed and found to contain a wide range of compounds, including fluorotelomer alcohols and related PFAS species. While GC-TOFMS enabled initial screening, high-resolution TOFMS was necessary to characterize unknown compounds through accurate mass determination and complementary ionization techniques (EI and PCI). This approach allowed tentative structural assignment using external databases, demonstrating the importance of HRMS in identifying compounds not present in standard libraries.The second case study focused on chewing gum, a highly complex matrix with diverse chemical constituents and trace-level analytes. The use of GC×GC-HRTOFMS significantly improved chromatographic separation and spectral clarity, enabling detailed profiling of volatile and semi-volatile compounds. A dedicated PFAS screening workflow based on mass defect analysis and spectral filtering was applied, leveraging the characteristic CF₂ patterns of PFAS molecules to simplify data interpretation.Despite the complexity of the sample, no PFAS were detected in the chewing gum, its packaging, or the box. Overall, the study demonstrates that combining GC×GC separation, high-resolution mass spectrometry, and advanced data processing tools provides a powerful and reliable strategy for untargeted PFAS screening in complex consumer products, particularly when unknown or emerging contaminants are of concern.<h3>3. Shimadzu: Gas Chromatograph Nexis GC-2060</h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c184_e056_06c3456516.pdf">Full PDF for download</a></li></ul>The Shimadzu <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=3&amp;search=Nexis+GC-2060">Nexis GC-2060</a> represents a new generation of gas chromatographs, built on over 70 years of GC development and designed to serve as a flexible and future-proof analytical platform. It integrates the concept of Analytical Intelligence, which enables automated system monitoring, troubleshooting, and optimization, helping both experienced and less experienced users achieve reliable and consistent results. The system is highly configurable, supporting up to two injectors, three injection units, and four detectors simultaneously, allowing a single instrument to cover multiple analytical applications.A key advantage of the Nexis GC-2060 is its versatility in sample introduction and detection. The Multi-Mode Injection Unit (MMI) supports a wide range of injection techniques, including split/splitless, PTV, direct injection, large-volume injection (LVI), and thermal desorption, significantly reducing the need for complex sample preparation. The system is also equipped with next-generation detectors such as FID and TCD, offering high sensitivity, stability, and linearity, with additional detector options (ECD, FPD, FTD, BID) enabling broad application coverage.The instrument is designed to maximize laboratory efficiency and minimize downtime. Features such as tool-free column installation (ClickTek), automated startup/shutdown, Easy sTop maintenance mode, and Clean Pilot for automated column conditioning simplify routine operation and reduce manual intervention. In addition, Eco Idling technology automatically optimizes gas and power consumption during standby, significantly lowering operational costs while maintaining readiness for analysis.From an analytical performance perspective, the Nexis GC-2060 delivers excellent reproducibility and sensitivity, supported by advanced autosamplers (e.g., AOC-30) and compatibility with third-party systems. The platform supports hydrogen carrier gas for faster analysis and includes smart gas management features such as automatic gas switching. Its modular design allows seamless integration with various sample preparation systems, autosamplers, and detectors, ensuring adaptability to evolving laboratory needs.Overall, the Nexis GC-2060 combines high performance, operational efficiency, and flexibility in a single platform, making it suitable for a wide range of applications, including pharmaceutical analysis, environmental testing, food analysis, and energy-related measurements. Its scalability and continuous software updates ensure long-term usability and alignment with future analytical requirements.<h3>4. Thermo Fisher Scientific: Accurate multi-component blast furnace gas analysis maximizes iron production and minimizes coke consumption</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/epm_AN_Iron_Production_Prima_PRO_bd5de98b44.pdf">Full PDF for download</a></li></ul>Over a billion tonnes of iron a year are produced in blast furnaces, representing around 94% of global iron production¹. The blast furnace consists of a large steel stack, lined with refractory brick. Iron ore, coke and limestone are dropped into the top of the furnace and preheated air blown into the bottom through nozzles called ‘Tuyeres’. Iron oxides are reduced in the melting zone, or ‘Bosh’, forming liquid iron (called ‘hot metal’) and liquid slag. These liquid products are drained from the furnace at regular intervals, and the blast furnace will run continuously for several years, until the refractory lining needs replacing.Analysis of carbon monoxide (CO) and carbon dioxide (CO₂) give vital information on the efficiency of the reduction processes. Historically, two non-dispersive infrared (NDIR) analyzers were used, one to measure CO, the other CO₂. Additional discrete analyzers were required to monitor oxygen and hydrogen – typically paramagnetic O₂ analyzers and thermal conductivity analyzers for H₂.&nbsp;Thermo Scientific™ process mass spectrometers have been widely used for many years for key gas analysis applications in iron and steel plants, including blast furnace, basic oxygen steelmaking, coke oven gas analysis, secondary steel process control, fuel gas analysis and direct reduction iron processes²<h4>Process control requirements&nbsp;</h4>The advantages of process MS over conventional analysis techniques have been proven over many years in the iron and steel industry. The ability to measure a wide range of components on a single analyzer, coupled with advanced calibration, data transmission, and self-diagnostic software, makes the modern mass spectrometer ideal for integration into the modern plant. On blast furnaces, superior gas analysis is being used to calculate gas efficiency, mass and heat balances, and heat profiles through probe analysis, as well as being an essential tool in the early detection of cooling water leaks and sample system failures.&nbsp;Figure 2 shows 64 hours of data from a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2305">Thermo Scientific™ Prima™ PRO Process MS</a> monitoring the six gases in a blast furnace top gas every 10 seconds. The pulse every 12 hours is generated by an automatic nitrogen blowback from the sample conditioning system, to keep the sample probe clear of particulates.<h4>Hydrogen analysis&nbsp;</h4>An increase in the hydrogen level in the furnace can indicate a leak from the furnace cooling system, as water dissociates into hydrogen and oxygen in the furnace. This has implications both for plant efficiency and plant safety. Water leaks will lower the furnace temperature, causing heat loss and a consequent increase in fuel consumption. In extreme cases, damage to plant and personnel can be caused by ignition of these hazardous mixtures of explosive gases.&nbsp;Figure 4 shows a plot of top gas hydrogen concentration measured by Thermo Scientific process MS over a 24-hour period, with the departure of the measured H2 value from that predicted by the mass balance model indicating a water leak. This leak was caused by the failure of a cooling member, and the furnace was taken off blast for repair. The mass spectrometer’s ability to provide fast, accurate hydrogen analysis removes the need for an additional discrete analyzer.&nbsp;Gas composition measurement is particularly important during the end-of-campaign blowdown that takes place prior to rebuilds and relines, because explosive gas mixtures can be generated.&nbsp;<h4>Probe analysis&nbsp;</h4>The fast analysis provided by MS offers another significant advantage over discrete analyzers—a number of process streams can be analyzed using a single instrument. This is achieved using a fully automated multi-inlet system, designed to switch between sample streams at high speeds with minimal sample flushing times. For example, as well as furnace top gas, the MS can also analyze gases from probes placed above and below the burden (the furnace charge of iron ore, coke and limestone). These are known as above-burden and sub-burden probes and provide valuable information on fuel efficiency, iron conversion and furnace charging. Figure 5 shows a schematic of these two probes; they can be moved across the furnace to build a cross-sectional profile of the furnace.<h4>Summary&nbsp;</h4>Thermo Scientific process mass spectrometers have been successfully monitoring blast furnace off gas at many of the world’s iron and steel companies for over 30 years. For a blast furnace producing 5,000 tonnes a day, a reduction in coke consumption of just 10 kg per tonne of iron produced provides a payback of over $10,000 a day. Users report that the combination of fast, accurate MS gas analysis for gas efficiency, heat and mass balances and hydrogen analysis, with advanced process control and mathematical modeling, has reduced coke consumption by up to 100 kg per tonne and increased iron production. Upgrading to Prima PRO MS can therefore result in complete installation payback within a few weeks.&nbsp;<ul><li>Reduces coke consumption&nbsp;</li><li>Produces consistent quality iron&nbsp;</li><li>Reduces downstream processing costs&nbsp;</li><li>Detects water leaks fast&nbsp;</li><li>Improves thermal control of furnace&nbsp;</li><li>Enables safer operation during blowdown</li></ul>

News from LabRulezGCMS Library - Week 14, 2026

<h3>We're excited to announce that <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity Chromatography Software</a> version 10.1.2 is now available!</h3>This minor update expands Clarity’s portfolio with new control modules.<h4>Newly added Instrument control modules</h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4>Updated Instrument control modules</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168">Ecom</a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328">Knauer</a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1">Changelog</a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622">Clarity 10.1 release highlights</a>.Clarity can control 1000+ instruments; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls">list can be previewed here</a>.</blockquote><h4>Supported Instruments in Clarity (DataApex) — Quick Guide</h4>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via digital control (DD) and analog acquisition (A/D) using the Colibrick module.<h5>Gas Chromatographs (GC)</h5>Digital integration over LAN/RS232 (many via ICF):<ul><li>Agilent: 5890, 6890, 7890, 8860, 8890, Intuvo 9000</li><li>Shimadzu: GC-2010/2014, Nexis GC-2030</li><li>Thermo Fisher: TRACE 1300/1310</li><li>PerkinElmer: Clarus 400–690</li><li>Also supported: Dani, Ellutia, Young In Chromass, Apix, Fuli, GOW-MAC (selected models)</li></ul><blockquote>Note: Most Agilent 6890–8890 and Intuvo use LAN – ICF.</blockquote><h5>HPLC Systems</h5>Full system/module control:<ul><li>Agilent 1100–1290 Infinity II (ICF)</li><li>Shimadzu LC-10/20 and Nexera LC-40</li><li>PerkinElmer Flexar / NexSAR</li><li>Knauer Azura / BlueShadow / Smartline</li><li>Hitachi Chromaster / Primaide</li><li>Young In Chromass ChroZen series</li><li>Sykam S500–S600, Watrex Streamline, Hanon LC7000–7300</li></ul><h5>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</h5><ul><li>Pumps: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li>Detectors: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li>Column Ovens: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li>Fraction Collectors: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5>Autosamplers</h5><ul><li>Agilent GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li>Shimadzu AOC-20 / AOC-5000+, SIL-10 / SIL-20 / SIL-40 series</li><li>CTC Analytics PAL, HTA autosamplers, Spark Alias/UHPLC, Knauer AS 6.1L</li><li>PerkinElmer Flexar / NexSAR AS</li></ul><h5>Other Devices</h5><ul><li>GC×GC modulators (e.g., Charles University GC×GC Modulator)</li><li>Valves &amp; switch modules (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li>Degassers, flow monitors, managers, interfaces</li><li>LC-MS / GC-MS: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li>Balances (EA extension): Mettler Toledo, Sartorius</li></ul><h5>Analog Acquisition (Colibrick)</h5>A/D support for legacy or analog-output devices:<ul><li>GC: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li>HPLC Detectors: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li>Elemental &amp; Amino Acid Analyzers: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul>If you are interested in a DEMO VERSION, contact us!

DataApex Clarity Chromatography software 10.1.2 just released!

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Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

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Shimadzu Corporation

Forensic chemists face the challenge of identifying new psychoactive substances (NPS), whereby the general structures of controlled drugs are modified to evade legislative banning.
Hence, a plethora of synthetic cathinones and cannabinoids has been available to the public, causing a global social problem. It is therefore crucial that analytical methods are developed for identifying and differentiating new analogues of synthetic drug substances, to prevent potential trading and abuse. Additionally, drug legislation is made more challenging with the use of synthetic cannabinoid containing products, typically marketed as “herbal mixtures”, which consists of analogues of synthetic cannabinoids. In this study, simultaneous multi-reaction monitoring (MRM) and product ion scan (PIS) acquisition methods have been developed for detection and differentiation of isomeric synthetic cannabinoids.
Data were acquired using a GC-MS/MS system (GCMS-TQ8050, Shimadzu Corporation, Japan) in electron ionization mode. Two classes of synthetic cannabinoids were analysed. They are a mixture of JWH-018 (1-pentyl-3-(1-naphthoyl)indole) and its seven other structural isomers, and a mixture of four positional isomers of fluoro-PB-22 (Quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate).
Learning Objectives:
<ul>
<li>Background of New Psychoactive Substance (NPS) and the types of synthetic cannabinoids
</li>
<li>Method development for the differentiation of eight structural isomers of JWH-018
</li>
<li>Method development for the differentiation of four positional isomers of Fluoro-PB-22
</li>
<li>Method applications on NPS-fortified samples
</li>
</ul>
<blockquote>
Presenter: Crystal Yeong (Ph.D.) (Senior Field Application Chemist, Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
Crystal Yeong is a senior field application chemist for GC and GCMS at Shimadzu (Asia Pacific) Pte Ltd in Singapore. She has experience in forensic applications, nitrosamines impurities detection and PAH analyses in edible oils. Prior to joining Shimadzu, she was a lab analyst with the Ministry of Home Affairs, Singapore. Crystal holds a PhD in Inorganic Chemistry and B.Sc. in Chemistry &amp; Biological Chemistry from Nanyang Technological University.
</blockquote>

Shimadzu: Digital Classroom: Using MRM/Product Ion Scan Mode in GC-MS/MS to Perform Detection and Differentiation of Synthetic Cannabinoids

Digital Classroom: Using MRM/Product Ion Scan Mode in GC-MS/MS to Perform Detection and Differentiation of Synthetic Cannabinoids

Simultaneous multi-reaction monitoring and product ion scan acquisition methods have been developed for detection and differentiation of isomeric cannabinoids.

Using MRM/Product Ion Scan Mode in GC-MS/MS

This webinar introduces Shimadzu&#39;s latest solutions for chemical ionization technique with GC/MS.
Three innovative solutions for chemical ionization will be introduced. Join us to learn about how seamless it is to adopt solvent-based chemical ionization technique in your current workflow with the solvent-mediated chemical ionization (SMCI) system. In addition, get to know how an innovative direct sampling tool and a unique Smart EI/CI ion source are capable of enabling consecutive electron and chemical ionization to supercharge your GC/MS analysis.
Learning Objectives:
<ul>
<li>Principle of chemical ionization
</li>
<li>Solvent mediated chemical ionization for safe and affordable CI capability
</li>
<li>Direct sampling for analysis of high molecular weight compound
</li>
<li>Smart EI/CI ion source for consecutive EI and CI analysis modes
</li>
</ul>
<blockquote>
Presenter: Chua Chun Kiang (Ph.D.) (Senior Application Chemist, Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
Chun Kiang is a Senior Application Chemist in Shimadzu Asia Pacific. He obtained his PhD from the Nanyang Technological University in Singapore in 2013 and has a diverse range of experiences in analytical and chemical sciences research. Prior to joining Shimadzu, he ventured into the vibrant Singapore tech startup scene.
</blockquote>

Shimadzu: Innovative Chemical Ionization Solutions for GC/MS

Innovative Chemical Ionization Solutions for GC/MS

Shimadzu's latest solutions for chemical ionization technique with GC/MS.

Have you ever wanted an alternate sample introduction method?
Maybe the sample of interest needs to be hotter than a standard inlet will reach. Pyrolysis is a sample introduction technique that uses elevated temperatures to break down organic materials. The starting samples can be anything from liquids to solids from many different application areas. Attend to get your questions answered by the experts.
On June 28th, Shimadzu Scientific and Frontier Ltd will be presenting “Expanding Material Characterization Capabilities Using Pyrolysis GCMS” where you will learn not only the fundamentals of this technique, but also the application uses.
<blockquote>
Presenter: Nicole Lock (GCMS Product Manager, Shimadzu Scientific Instruments)
</blockquote>
<blockquote>
Nicole Lock is the GCMS Product Manager at Shimadzu Scientific Instruments. Nicole graduated from Seton Hill University with a Bachelor of Science in Chemistry. She started her career as a service engineer in a small third-party service organization repairing multiple brands’ GC and GCMS units. This skill set led Nicole to Shimadzu where she has spent the last 12 years working in both the service and marketing department representing the GC and GCMS product lines. Her passion is training others on Shimadzu GCMS and helping customers make the most of their systems.
</blockquote>
<blockquote>
Presenter: Rojin Belganeh (Technical &amp; Marketing Director, Frontier Laboratories-North America)
</blockquote>
<blockquote>
Rojin Belganeh is the Technical &amp; Marketing Director at Frontier Laboratories-North America. Rojin graduated from the University of Houston with a Bachelor of Science in Chemistry. She started her profession as an analytical chemist in oil &amp; gas industry in 2012. As an analytical chemist, Rojin worked with various analytical instruments, such as Pyrolysis GCMS, TGA, FTIR, and X-Rays for material characterization, polymer identification, and contamination analysis. She also holds an MBA degree concentrating in strategic marketing from the University of Houston-Victoria. As a former user for more than five years, Rojin joined Frontier Laboratories in May of 2017. She is very passionate in creating awareness about Frontier technology and providing technical support to users.
</blockquote>
<blockquote>
Presenter: William Pipkin (Global Marketing, Frontier Laboratories)
</blockquote>
<blockquote>
William Pipkin has over 30 years experience in commercializing technology. This includes all aspects: sales, support, marketing, R&amp;D, and management. He has directed inception and development through sales, support, and obsolescence. William has expertise in strategy, market research, market segmentation, advertising, sales promotion, pricing, and customer service. His experience is international including Europe, Japan, and China. His teams and collaborations have been cross-functional, cross-entity, and cross-cultural.
</blockquote>
<blockquote>
William received a Bachelor of Science in analytical chemistry (American Chemical Society certified) from Brigham Young University and an MBA in entrepreneurship and finance (Dean’s List) from The Wharton School of the University of Pennsylvania. He has been a Senior Fellow in Wharton&#39;s Emerging Technology Management Research Program.
</blockquote>
<blockquote>
Presenter: Atsushi Watanabe (Vice President, Frontier Laboratories)
</blockquote>
<blockquote>
Atsushi Watanabe (known as Ichi-san) obtained his Associate of Chemistry and Biochemistry from Fukushima National College of Technology. He then studied in Vancouver, Canada at the University of British Columbia where he earned a BS in Commerce and General Business Management. He is currently in the process of defending his PhD in analytical pyrolysis at Tohoku University. He is a Vice President in Frontier Laboratories and a member of the board. Currently Ichi-san heads up global marketing and IT. Ichi-san has 4 publications in Japanese and 13 international publication in English. He also serves as a committee member of Japan Gas Chromatography Research Group.
</blockquote>

Shimadzu: Expanding Material Characterization Capabilities Using Pyrolysis GCMS

Expanding Material Characterization Capabilities Using Pyrolysis GCMS

Learn not only the fundamentals of this technique, but also the application uses.

Expanding Material Characterization Capabilities by Py-GC/MS

The increasing complexity of the food supply chain, the exponential growth of chemical hazards and their regulations have brought several challenges to the field of food safety.
The need for productive gains and increased confidence in reporting non-compliant samples are particularly noteworthy challenges for laboratories that are routinely relied upon for maintaining a safe food supply chain. To meet these demands, mass spectrometric techniques such as tandem mass spectrometry and quadruple-time-of-flight mass spectrometry have emerged as the detectors of choice for the analysis of organic chemical hazards in foods and beverages.
One of the more recent significant developments is Shimadzu’s ultra fast family of mass spectrometric detectors that provide opportunities to increase both productivity and reporting confidence compared with more conventional mass spectrometric detectors. The importance of these state-of-the-art instruments to the analysis of chemical hazards in food will be discussed in the context of the regulatory requirements for the analysis of contaminants in foods and a general overview of chemical hazards in foods.
By viewing this webinar you will:
<ul>
<li>Understand the core challenges for food testing
</li>
<li>Recognize the key elements that can accelerate and streamline your workflow and increase your data confidence
</li>
<li>Learn and apply in various food safety analysis (e.g. multi-residual pesticides, veterinary drugs and mycotoxins).
</li>
</ul>
Who should view it?
<ul>
<li>Scientists and lab personnel conducting food analysis
</li>
<li>Lab managers in testing lab, regulatory agency and the food industry
</li>
<li>Everyone who is keen to increase their lab productivity and data confidence for food and beverage analysis.
</li>
</ul>
<blockquote>
Presdenter: Dr Peter Varelis (Applications Manager, Shimadzu Scientific Instruments (Oceania) )
</blockquote>
<blockquote>
Dr Peter Varelis has more than 20 years of research experience in both government and industry. He was also on an Elsevier editorial board (Food Chemistry and Analysis). His current research interest is the application of mass spectrometry to investigate organic compounds that have implications for human health and nutrition.
</blockquote>

Shimadzu: The Importance of Ultra Fast Mass Spectrometry for the Analysis of Chemical Hazards in Food & Beverages

The Importance of Ultra Fast Mass Spectrometry for the Analysis of Chemical Hazards in Food & Beverages

Understand the core challenges for food testing.

Ultra Fast Mass Spectrometry in Food & Beverages analysis

This exclusive Shimadzu Food Safety Webinar will provide an in-depth know-how about the various mass spectrometry (MS/MS) workflows that are needed to conduct high throughput pesticide analysis in challenging matrices.
You will learn about the latest state-of-the-art technologies that mass spec leaders are using globally to deal with pesticide analysis in difficult matrices such as spices and tobacco.
This webinar will be useful for anyone who is keen to learn about the latest advanced MS/MS technologies and will be particularly interesting for those who have faced difficulties while using challenging matrices.
By viewing this presentation you will learn...
<ul>
<li>about the practical aspects of MS/MS analysis using challenging matrices
</li>
<li>how these methods can be applied to such samples as spices and tobacco
</li>
</ul>
<blockquote>
Presenter: Dr Kaushik Banerjee
</blockquote>
<blockquote>
Dr Kaushik Banerjee is a National Fellow and Principal Scientist from the ICAR-National Research Centre for Grapes, Pune, India.
</blockquote>

Shimadzu: Spice Up Your Life with MS: Workflows for High Throughput Pesticide Analysis by MS/MS in Challenging Matrices such as Spices and Tobacco

Spice Up Your Life with MS: Workflows for High Throughput Pesticide Analysis by MS/MS in Challenging Matrices such as Spices and Tobacco

Know-how about the various mass spectrometry (MS/MS) workflows that are needed to conduct high throughput pesticide analysis in challenging matrices.

MS/MS Workflows for High Throughput Pesticide Analysis

This webinar will clarify the regulatory status and analytical methods applied for the analysis of mineral oil contaminants, in the form of both saturated (MOSH) and aromatic hydrocarbons (MOAH), in edible oils and food contact materials.
While LC-GC-FID is the standard instrumentation to monitor the levels of these contaminants, multiple sample clean-up techniques must be performed to improve the method robustness and sensitivity.
Join us to learn how Axel Semrau and Shimadzu come together to deliver the best automated solution for your food safety analysis needs.
For the love of food!
Learning Objectives:
<ul>
<li>An update on the regulatory status and analytical methods for MOSH/MOAH analysis
</li>
<li>LC-GC-FID is the standard instrumentation to monitor the levels of these contaminants
</li>
<li>Automated clean-up techniques for the analysis of MOSH/MOAH samples
</li>
</ul>
<blockquote>
Presenter: Yoann Costa (R&amp;D Engineer, Phytocontrol)
</blockquote>
<blockquote>
Started working for Phytocontrol in 2017 at the end of my study in chemistry. Currently a R&amp;D engineer working on development and validation of analytical method for contaminants in food. Had the opportunity to work on different types of contaminants in food such as pesticides and MOSH/MOAH with a large variety of analytical techniques (LC-MS/MS, GC-MS/MS, LC-GC-FID,...)
</blockquote>
<blockquote>
Presenter: Dr. Andreas Bruchmann (Managing Director, Axel Semrau GmbH &amp; Co KG)
</blockquote>
<blockquote>
After studying Analytical Chemistry at the University of Bochum, Andreas Bruchmann joined Axel Semrau in 1992. He worked in different departments before becoming Managing Director in 2010. Now he is responsible for the business unit Chromatography, which supplies worldwide automated application solutions for the food and pharmaceutical industry. He was involved in the development of the CHRONECT MOSH/MOAH Workstation from the beginning in 2010.
</blockquote>
<blockquote>
Presenter: Ang May Yen (Application Manager, Shimadzu Malaysia Sdn Bhd)
</blockquote>
<blockquote>
Graduated with a Master Degree in Science (Marine Biotechnology) and Bachelor Degree in Science (Industrial Chemistry) from Universiti Malaysia Sabah. 13 years experienced in handling and conducting training on analytical instruments such as UV-VIS spectrophotometer, Atomic Absorption Spectrometry (AAS), Fourier Transform Infrared Spectroscopy (FTIR), High Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), High Performance Liquid Chromatography Mass Spectrometer (LCMS, LCMSMS) and Gas Chromatography Mass Spectrometer (GCMS, GCMSMS).
</blockquote>
<blockquote>
Currently holding a position as Application Manager for Customer Support Centre, Analytical Instrument Division, Shimadzu Malaysia Sdn. Bhd.
</blockquote>

Shimadzu: For the Love of Food! Food Safety and the Analysis of MOSH/MOAH Contamination

For the Love of Food! Food Safety and the Analysis of MOSH/MOAH Contamination

The regulatory status and analytical methods applied for the analysis of mineral oil contaminants, in the form of both saturated and aromatic hydrocarbons.

Food Safety and the Analysis of MOSH/MOAH Contamination

In this webinar, our panel of experts will discuss the market for alcohol-based hand sanitizers, the current regulatory environment, as well as analytical solutions including gas chromatography, Fourier-transform infrared spectroscopy, and UV-Vis spectroscopy to ensure the purity, potency, and safety of alcohols and hand sanitizers.
<blockquote>
Presenter: Nicole Zhang (Senior Product Specialist, Shimadzu Asia Pacific)
</blockquote>
<blockquote>
Nicole studies in UK in Microbiology and Immunology, prior joining Shimadzu, she worked in different companies in analytical instrument industry for more than 10 years, from Chemist to marketing and in charge of different technologies from LC, MS to Spectro products. She joined Shimadzu at the year of 2018 as spectroscopy product specialist and in charge of food quality and safety market.
</blockquote>
<blockquote>
Presenter: Jackie (Product Specialist (GC &amp; GCMS), Shimadzu Asia Pacific)
</blockquote>
<blockquote>
After graduating from the National University of Singapore, Jackie has garnered over 6 years of research, training and facilitation experience. Jackie meets scientists from various industries to share technical knowledge and collect feedback, understanding their problems and helping them find well-suited solutions in GC-related analyses.
</blockquote>

Shimadzu: Stay Safe! Comprehensive Analysis of Alcohols and Hand Sanitizers

Stay Safe! Comprehensive Analysis of Alcohols and Hand Sanitizers

The market for alcohol-based hand sanitizers, the current regulatory environment, as well as analytical solutions including gas chromatography.

Comprehensive Analysis of Alcohols and Hand Sanitizers

Struggling with those pesky software roadblocks that break your workflow? Join our technical show-and-tell software series where we tackle the most frequently asked (and frustrating) software questions. From retention time locking, PCDLs, AMDIS libraries, retention indices, and deconvolution, our experts will decode the chaos with insights and examples. Whether you’re feeling like a pro or just trying to keep your system running, questions always arise. This event is your chance to get real answers.What you will learn:<ul><li>When to use retention time locking</li><li>How to set up retention time locking&nbsp;</li></ul><blockquote>Presenter:&nbsp;Erinn O'Neill (GC/MS Applications Scientist, Agilent)Erinn O’Neill is a GC/MS presales application scientist for Agilent in Wilmington, Delaware. She graduated from the University of North Carolina at Chapel Hill with a PhD in chemistry in 2019, where she focused on identifying novel chemical structures synthesized by plant-pathogenic bacteria. Before that, she obtained a Bachelor’s degree in chemistry from Drew University in New Jersey, where she studied reactions between atmospheric aerosol surrogates and trace pollutants.</blockquote>

Agilent Technologies: Ctrl+Alt+Del Your Software Struggles - Technical Show-and-Tell Sessions

Understand Retention Time Locking

Join this webinar and learn when to use retention time locking and how to set up retention time locking.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div>Join us for an in-depth webinar where we explore the exciting new functionalities of reporting in Chromeleon Chromatography Data System (CDS). This session will provide you with advanced reporting tips and tricks to enhance your data analysis and reporting capabilities. Whether you are a seasoned user or new to Chromeleon CDS, this webinar will equip you with the knowledge to maximize the potential of reporting, streamline your workflows, and generate insightful reports with ease.<h5>Key takeaways:</h5><ul><li>Discover the latest features and enhancements</li><li>&nbsp;Learn advanced tips and tricks for creating comprehensive reports</li><li>Understand how to customize and automate your reporting processes</li><li>Get answers to your specific questions during the live Q&amp;A session</li></ul><h5>Who should attend:</h5><ul><li>Chromeleon CDS users looking to upgrade their reporting skills</li><li>Laboratory managers and analysts seeking to improve data reporting efficiency</li><li>Anyone interested in learning more about the capabilities of Chromeleon CDS</li></ul>Don't miss this opportunity to elevate your reporting skills and make the most out of Chromeleon CDS. Register now to secure your spot!<blockquote>Presenter: Kimy Young (Senior Manager, Software Product Specialists, Thermo Fisher Scientific)Kimy Young is the Senior Manager of software product specialists at Thermo Fisher Scientific. She has been with Thermo Fisher since November 2015. Her background includes administration of Chromeleon CDS, laboratory information management systems (LIMS), Quality Assurance (QA), and IT projects.Presenter: Juan Carmona (Chromeleon CDS Specialist, Thermo Fisher Scientific)Juan Carmona is a Chromeleon Specialist at Thermo Fisher Scientific based out of Pflugerville, TX. He has been with Thermo Fisher Scientific for over 15 years. At Thermo Fisher Scientific, he is currently focusing on expanding the customer base using Chromeleon CDS for small networks and enterprise deployments. Prior to joining this group, he was part of the GC/GCMS Center of Excellence team providing support for the product line.Presenter: Monica Driscoll (Regional Marketing Specialist, Thermo Fisher Scientific)</blockquote></div></div></div>

Thermo Fisher Scientific: Chromeleon CDS webinar series

Harness the power of Chromeleon CDS reporting

Join this webinar to explore new Chromeleon CDS reporting features, advanced tips, and automation tools to boost efficiency and data insights.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div>Join us as we demonstrate how you can customize data processing workflows in Thermo Scientific™ Compound Discoverer™ software using Scripting Nodes. This session will guide you through enhancing your workflows by accessing the Compound Discoverer software result database and integrating any custom calculations via R -or Python scripts. Learn how to seamlessly integrate your existing in-house software, allowing you to export, read, and process result tables, and directly return the results as new columns or tables within the Compound Discoverer software.<h5>Webinar Objectives:</h5><ul><li>Understand the various methods to customize data processing workflows</li><li>Learn how to access the Compound Discoverer software result database, understand connections between tables, and how to export relevant information</li><li>Gain practical knowledge on developing scripts that read information from the database and return results as new columns or tables, enhancing the functionality and utility of your workflows</li></ul><blockquote>Presenter: Dr. Ralf Tautenhahn (Manager, Product Applications, Thermo Fisher Scientific)Dr Ralf Tautenhahn earned his PhD in Bioinformatics (2009) at the Martin-Luther University. In 2013, Ralf joined Thermo Fisher Scientific as a platform manager for metabolomics software. Over the last 10 years he has overseen the development of the Thermo Scientific Compound Discoverer software for small molecule research.Presenter: Zoe Julian (Product Marketing Manager, Thermo Fisher Scientific)</blockquote></div></div></div>

Thermo Fisher Scientific: Customizing Compound Discoverer Software: How to Create a Scripting Node

Customizing Compound Discoverer Software: How to Create a Scripting Node

How you can customize data processing workflows in Thermo Scientific™ Compound Discoverer™ software using Scripting Nodes. 