Researchers&nbsp;Tereza Nešporová and Jaroslava Večerková from Brno's RECETOX explain why failures are also a valuable part of gaining knowledge, how they study the effects of chemical substances on the hormonal system, and why they apply their professional insights to their everyday lives.<h5>How did you get involved in research at RECETOX?&nbsp;</h5>Jaroslava: I actually joined RECETOX by chance during my follow-up Master's studies in Environmental Chemistry, back when Professor Holoubek was still leading the institute. I wrote my thesis under Klára Hilscherová and simply stayed here ever since, except for a break during maternity leave. I have been part of her team the whole time, focusing on endocrine disruptors.&nbsp;What has changed over the years is the focus of our research. We used to study surface waters, particularly the presence of substances with endocrine-disrupting potential and their effects on organisms. Today, the research has shifted more toward humans and the interactions between chemical substances and the endocrine system.&nbsp;Tereza: I came from a completely different field. I studied molecular biology and worked on chronic lymphocytic leukemia for my Master's thesis at CEITEC. I used genetic engineering methods such as CRISPR/Cas9 for gene editing—activating, suppressing, or completely removing genes.&nbsp;At the time, Klára Hilscherová’s group needed to create cellular models with increased production of deiodinase enzymes, which I still work on today. I had heard only positive things about the team, and when I finished my Master's degree, I wanted to move beyond my original field. The connection between hormones and neurodevelopment attracted me, and RECETOX became the obvious choice.&nbsp;<h5>So you are in the same research team. How do you collaborate?&nbsp;</h5>Tereza: We sit in the same office. And that’s probably the main thing (laughs).&nbsp;Jaroslava: We discuss things a lot. Some mechanisms repeat across experiments, so we talk about how each of us evaluates data and why. We inspire each other, even though we do not directly collaborate on the same laboratory work.&nbsp;<h5>How does your work differ?&nbsp;</h5>Tereza: Our team is highly interconnected. We all work on developing assays for detecting endocrine-disrupting substances, specifically those affecting thyroid hormones. However, each of us focuses on a different part of the system.&nbsp;I focus on deiodinase enzymes, which regulate the activation and deactivation of hormones. Recently, I have been spending more time analyzing data and designing experiments than working directly in the laboratory.&nbsp;Jaroslava: Within the team, I mainly participate in testing different types of samples—from individual chemicals and mixtures to real environmental samples such as household dust—using the assays mentioned above.&nbsp;It is important to note that chemicals can affect the hormonal system at different levels. They can bind to or block nuclear receptors, affect hormone transport in the bloodstream, or interfere with hormone metabolism. In the past, only one part of this process was monitored. Today, we aim to cover the full spectrum of these interactions.&nbsp;Tereza: And that is crucial. A substance may appear negative in one test, yet affect another part of the system, producing a significant impact on the organism. That is why current research focuses on the entire range of possible mechanisms.&nbsp;<h5>Why did you choose endocrine disruptors as your research topic?&nbsp;</h5>Jaroslava: For me, it was more or less a coincidence while choosing my thesis topic. But it turned out to be a fascinating area, so I stayed with it.&nbsp;Tereza: I had been interested in it for a long time. I also like that our work has a concrete outcome—we develop tests that can realistically be used in decision-making regarding the safety of chemical substances. Compared to my previous research, I feel this work has a much more direct application.&nbsp;<h5>What about your PhD studies?&nbsp;</h5>Jaroslava: My PhD studies are currently on hold. After maternity leave, I returned as a laboratory technician, and my project work gradually shifted away from my original doctoral topic.&nbsp;Tereza: I am currently in the fourth year of my PhD studies. I also completed a research stay in Germany, where I learned to work with neuronal cells.&nbsp;As part of my studies, I focus mainly on deiodinases—the enzymes that act as the “on and off switches” of thyroid hormones. We are developing a test that can measure the effects of chemical substances on their activity.&nbsp;In addition, we are now studying how these substances affect neurons and their development, because proper thyroid hormone levels are crucial for nervous system development.&nbsp;<h5>What is the most challenging aspect of laboratory work?&nbsp;</h5>Tereza: Probably unpredictability. Cells do not always grow as expected, instruments have their bad days, and human error also plays a role. The important thing is to document all mistakes and complications and learn from them.&nbsp;Jaroslava: I agree with Tereza. The biggest challenge is unpredictability. Cells are living systems and do not always behave the same way.&nbsp;<h5>Can a career in science be combined with parenthood?&nbsp;</h5>Jaroslava: At RECETOX, definitely. There is a great deal of flexibility, and managers are very supportive. When necessary, it is possible to work from home. We help each other a lot within the team.&nbsp;Tereza: It also depends on the type of work and whether it can be planned according to your needs. Our team collaborates closely and tries to help one another whenever necessary. That is key. And when needed, data analysis and manuscript writing can also be done from home.&nbsp;<h5>Is your work more routine or highly varied?&nbsp;</h5>Jaroslava: Very varied. Laboratory work alternates with computer-based work. We are constantly learning new things. It is definitely not repetitive or boring, and that is what I enjoy about it.&nbsp;Tereza: The only routine in my work is taking care of cell cultures. Otherwise, the work is constantly changing. That is also what I enjoy most about it.&nbsp;<h5>What are the biggest challenges in your work?&nbsp;</h5>Jaroslava: Data evaluation. Measuring something is one thing; evaluating and interpreting it correctly is another.&nbsp;Tereza: Implementing new methods. And also those moments when you do everything correctly according to a published protocol, yet the results still do not match expectations.&nbsp;In science, you have to learn to accept that not everything works the first time. The important thing is not to give up, to continue optimizing, and to keep hoping for success.&nbsp;<h5>What role should open science play?&nbsp;</h5>Tereza: A huge one. If we had access to detailed protocols and original datasets, it would save enormous amounts of time and money during the implementation and optimization of new methods. Scientific papers often omit details that are actually critical for experimental success.&nbsp;Jaroslava: It is also important to share failures. A negative result is still a result, and it can provide valuable information.&nbsp;<h5>You are both mothers. Does your work influence your personal lives?&nbsp;</h5>Jaroslava: Absolutely. For example, we pay close attention to washing fruit because of chemical treatments. I encourage my children to think about what they consume, what it contains, and where it comes from. We try to avoid plastics and consistently separate waste.&nbsp;Tereza: Definitely. Even before having a child, I paid close attention to the composition of cosmetics, food, and other products. After becoming a parent, my caution multiplied.&nbsp;I was especially careful during pregnancy because a developing organism is most sensitive to harmful substances. Sometimes relatives raise their eyebrows at this, but when we have information firsthand, we cannot simply ignore it.&nbsp;Jaroslava: We also pay attention to toys, clothing, and materials used in the home. It is a kind of professional deformation (laughs).&nbsp;<h5>How can your research contribute from a broader perspective? How can others build upon it?&nbsp;</h5>Jaroslava: We are gradually optimizing methods that may eventually be used routinely. That is probably our greatest contribution.&nbsp;Tereza: Yes, our methods could help identify undesirable effects of substances before they reach the market, potentially leading to regulation of their production.&nbsp;<h5>Would you like to continue working on this topic in the future?&nbsp;</h5>Jaroslava Večerková: The topic of endocrine disruption is extremely interesting and very broad. The direction of research may change depending on current projects, but I would like to remain part of the team.&nbsp;Tereza Nešporová: I am very interested in uncovering how substances affect human health, and I believe I will want to continue working in this area. I like how dynamic the research is and that it has direct practical applications. I do not mind change, but I am happy within this team and would like to stay. We work together as a well-coordinated group.&nbsp;

Researchers Tereza Nešporová and Jaroslava Večerková: In science, we must learn to work with failure

Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning, today announced the release of the multi-format <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2461">NIST / EPA / NIH EI Mass Spectral Library 2026 </a>and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2462">NIST MS/MS Spectral Library 2026</a>.Developed by the experienced mass spectrometry (MS) team at the National Institute of Standards and Technology (NIST), these databases represent the culmination of more than four decades of comprehensive evaluation and expansion, making it an essential resource for those analyzing mass spectra.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_NIST_EPA_NIH_EI_Mass_Spectral_Library_2026_af64f091bd.jpg" alt="Wiley: NIST / EPA / NIH EI Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_NIST_EPA_NIH_EI_Mass_Spectral_Library_2026_af64f091bd.jpg 111w," sizes="100vw" width="1531" height="2159"><h4>New in the 2026 release:</h4><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2461">NIST/NIH/EPA EI Mass Spectral Library</a> includes 35,000+ new compounds, bringing the total to 431,000+ EI (electron ionization) spectra, with expanded coverage of biologically, environmentally, and industrially relevant compounds.</li><li>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2462">NIST MS/MS Mass Spectral Library</a> now contains 3.2 million+ spectra across 68,600+ compounds, spanning metabolites, drugs, pesticides, peptides, lipids, glycans, extractable and leachable compounds, surfactants, and contaminants.</li><li>The GC Retention Index Library added over 35,000 compounds, further enhancing compound identification workflows.</li><li>The underlying NIST MS Search software has also been extensively updated and now includes chromatogram analysis for GC-MS or LC-MS/MS workflows.</li><li>From 2026, the EI and MS/MS libraries are available as separate products. Both can be ordered through Wiley, with bundle options available.</li></ul>“Wiley distributes NIST EI 2026 in more instrument formats than any other NIST 2026 provider,” said Graeme Whitley, Senior Director, Data Science Solutions at Wiley. “In addition to the standalone NIST libraries, Wiley also offers customers the option to extend their capabilities with the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/887">Wiley Registry </a>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/934">KnowItAll GC-MS</a> and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1942">LC-MS libraries</a>, delivering broader coverage and flexibility for evolving analytical workflow needs.”The EI library is available in multiple instrumentation manufacturer formats, while the MS/MS library is provided in NIST format. Together, these libraries support high-confidence analysis across GC-MS and LC-MS workflows, helping laboratories confidently improve identification and streamline analytical processes.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_NIST_MS_MS_Mass_Spectral_Library_2026_899749d679.jpg" alt="Wiley: NIST MS/MS Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_NIST_MS_MS_Mass_Spectral_Library_2026_899749d679.jpg 110w," sizes="100vw" width="1526" height="2160"><h5>Learn more at Wiley Science Solutions:</h5><ul><li>Visit our web for more information about the <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/gc-ms/nist-epa-nih-mass-spectral-library/">NIST/EPA/NIH EI Mass Spectral Library 2026</a></li><li>Visit our web for more information about the <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/lc-ms/nist-ms-ms-mass-spectral-library-2026/">NIST MS/MS Mass Spectral Library 2026</a></li></ul><h5>About Wiley</h5>Wiley is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning.&nbsp;

Wiley Releases NIST Mass Spectral Library 2026 in Multiple Instrument-Ready Formats

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 6th July 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you brochure by Agilent Technologies, presentation by MDCW / University of Washington and posters by Shimadzu / ASMS and Thermo Fisher Scientific / ASMS!<h3>1. Agilent Technologies: Operational efficiency for your GC and GC/MS labs with the Agilent 8860B gas chromatography system</h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/br_8860b_gc_5994_9206en_agilent_7b7b766cd2.pdf">Full PDF for download</a></li></ul><section><div><div><div><div><div><div>The brochure presents the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8860B">Agilent 8860B GC system</a> as a routine GC and GC/MS platform focused on operational efficiency, reliable performance, intelligent diagnostics, and sustainability. It is positioned as a next-generation GC workhorse for laboratories that need consistent, high-quality data while increasing throughput and reducing downtime. Key performance features include dual sample injection capabilities, improved repeatability for retention time and peak area, electronic pneumatics control, retention time locking for method transfer, and a built-in oven light to simplify maintenance and column installation.A major theme is instrument intelligence through the Agilent GC Assist interface. The system provides browser-based access to instrument status, methods, sequences, logs, diagnostics, maintenance information, and help resources. Built-in tools such as early maintenance feedback, system health reporting, automated and user-initiated diagnostics, peak evaluation, and self-guided troubleshooting are designed to help laboratories detect issues early, maintain uptime, and reduce the need for expert-level intervention during routine operation.The brochure also emphasizes sustainability and resource management. The 8860B GC includes gas and power usage reporting, method-based monitoring, alerts for abnormal gas use, and tools for detecting possible leaks or restrictions. Agilent highlights helium conservation options, including a helium conservation module that can reduce helium consumption by switching to an alternative gas during idle periods, as well as support for hydrogen and nitrogen carrier gases with built-in hydrogen safety features. These functions are presented as ways to reduce operating costs, conserve resources, and protect workflows from helium supply disruptions.Finally, the brochure describes the broader Agilent GC ecosystem around the 8860B. The system supports multiple inlets, detectors, autosamplers, headspace sampling, single quadrupole GC/MS compatibility, OpenLab CDS, DA Express, MassHunter software, Agilent consumables, columns, and CrossLab services. Together, these elements are presented as a complete workflow for routine laboratories that need flexibility, compliance support, service coverage, method consulting, training, and long-term value from their GC investment.<h3>2. MDCW / University of Washington: Implementing Tile-Based Fisher Ratio Analysis of GC×GC-TOFMS Data to Obtain a Master Peak Table of All Detected Analyte Compounds in Many Petroleum-Based Samples</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_9_Halvorsen_136808e314.pdf">Full PDF for download</a></li></ul><section><div><div><div><div><div><div>The presentation describes the development of a chemometric workflow for advanced fuel sample analysis using GC×GC-TOFMS data. The work was carried out by the University of Washington in collaboration with Chevron Technical Center, with the goal of improving the characterization of complex petroleum-based samples. Moving from conventional GC to comprehensive two-dimensional GC increased peak capacity and chromatographic resolution, but also created the need for more advanced methods to generate reliable peak tables across many chemically diverse fuel samples.The key method presented is a tile-based Fisher Ratio approach implemented through <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/348">ChromaTOF Tile</a>. This method identifies analytes that show statistically significant concentration differences between sample classes. Instead of relying only on peak detection or manual alignment, the workflow uses chromatographic “tiles” to reduce the impact of retention-time shifting and to capture both major and trace-level components. The study included multiple fuel classes, including hydrobate, reformate, naphtha, FCC gasoline, and blanks.Because Fisher Ratio values alone do not directly indicate whether a compound is truly detectable, the authors added a blank-based p-testing strategy. Three blank chromatograms were used to estimate background signal distributions for each tile, and confidence intervals were then applied to determine whether each detected hit was present in individual sample classes. This produced a master peak table covering 719 hits across nine fuel sample classes. The results showed good reproducibility, with only 6.3% of classifications being heterogeneous across replicates.Overall, the presentation concludes that the tile-based workflow can generate comprehensive and reproducible peak tables with reduced user intervention, while preserving the ability to recover trace analytes in complex petroleum samples. The approach should be broadly applicable to other complex sample types and could also be adapted using chemometric metrics other than Fisher Ratio, depending on the experimental design and analytical goals.<h3>3. Shimadzu / ASMS: Is Your Next Sip Safe? A Simple, Rapid Method for Measuring volatile PFAS in Juices.</h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/TP_143_Is_Your_Next_Sip_Safe_A_Simple_Rapid_Method_for_Measuring_volatile_PFAS_in_Juices_a6ed9414c0.pdf">Full PDF for download</a></li></ul>Per- and polyfluoroalkyl substances (PFAS) pollution is a growing global concern due to links with adverse health effects, many of which remain poorly understood. 1 Accurate detection and quantification are therefore essential. While PFAS analysis has traditionally focused on water, attention is rapidly expanding to food and beverages, where testing remains limited despite high stakes and increasing regulations. 2 A recent PFAS lawsuit against a juice manufacturer underscored the heightened public scrutiny of PFAS in juices, placing food safety and brand reputation at risk. 3 This study presents a Headspace Solid-Phase Microextraction– Triple Quadrupole Gas Chromatography/Mass Spectrometry (HS-SPME GC/MS/MS) method for PFAS quantitation in juices. GC/MS enables analysis of volatile PFAS unsuitable for LC/MS, while HS-SPME offers rapid analysis with minimal sample preparation in complex matrices.<h4>Methods</h4>A volatile PFAS analysis method was developed on a Shimadzu <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ8040+NX">GCMS-TQ8040 NX</a> with an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=AOC-6000+Plus">AOC-6000 Plus multifunctional autosampler</a> equipped with a solid phase microextraction (SPME) module (Figure 1).<h4>Results&nbsp;</h4>The system was deemed free of contaminants and inferences. None of the target PFAS in the method blank were found in quantifiable concentration. In the study, the calibration curve for each target included at least seven calibrators. Calibration curve results showed a good linear fit for all compounds with coefficient of determination (R2 ) ≥ 0.993. The linear range and R2 of each PFAS target are shown in Table 3.<h4>Conclusion</h4>Overall, these results demonstrate the robustness and reliability of the method for PFAS analysis in two carton apple juices (Brands X and Y), one plastic bottled apple juice (Brand X), and a berry blend carton juice (Brand X). Given the diversity of matrices evaluated, the method may also be suitable for other beverages, including sports drinks and vitamin-enhanced waters<h3>4. Thermo Fisher Scientific / ASMS: Enhanced sensitivity for the quantitative analysis of pesticides using a GC Orbitrap MS</h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_004706_lsms_pesticides_exploris_gc_efs_po004706_asms2026_na_en_5f51b18742.pdf">Full PDF for download</a></li></ul>Detection of pesticide residues in fruits and vegetables is essential for food safety, but it can be challenging in complex, highly pigmented matrices due to interferences. Orbitrap technology provides high resolution and mass accuracy, enabling confident identification of coeluting and isobaric compounds while reducing false results. Furthermore, the FS-HRAM acquisition enables simultaneous quantitation and screening within a single analysis with the capability of retrospective data analysis, allowing laboratories to reprocess datasets for additional or emerging compounds without re-injecting samples. The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2419">Orbitrap Exploris GC S mass spectrometer</a> features the Thermo Scientific NeverVent Advanced Electron Ionization Source (NVAEI) which offers an improved design providing enhanced sensitivity and robustness, allowing for increased instrument uptime and maximized sample throughput for rapid return on investment (ROI).<h4>Materials and methods</h4><h5>Data analysis&nbsp;</h5>Data was acquired, processed and reported using the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76">Thermo Scientific Chromeleon Chromatography Data System (CDS) software</a>, which provides integrated instrument control, automated workflows, and an intuitive interface for data analysis, customizable reporting, and compliant data management in accordance with FDA 21 CFR Part 11 and European Commission (EU) Annex 11. Its advanced reprocessing capability streamlines sequence setup, data review, and reporting offering the possibility to easily flag and check compliance with the current regulations.Results Compliant analyte identification The use of HRAM-GCMS reduces the matrix interferences ensuring a confident and selective identification of analytes (Figure 1). All target compounds satisfied the SANTE criteria at the default MRL of 10 µg/kg and more than 90% were confirmed at concentrations of 1 µg/kg following the SANTE/11312/2021v2026 guidance criteria of:&nbsp;<ul><li>two ions were detected for each pesticide with mass accuracy ≤ 5 ppm with precursor and product ions in the extracted ion chromatograms fully overlapped,&nbsp;</li><li>due to the added value of accurate mass measurement, matching ion ratios is not necessary, however, an ion ratio (IR) deviation within ± 30% (relative) of the average of calibration standards from the same sequence was considered to provide additional support for identification</li><li>retention times (RT) within a tolerance of ± 0.1 minutes</li></ul>Sensitivity performance (IDL) and analytical linearity Instrument sensitivity was evaluated using calculated IDLs derived from replicate injections of low-level, matrix-matched standards. The Orbitrap Exploris GC S demonstrated detection limits at levels at or below 0.5 µg/kg for most of the investigated pesticides (Figure 2). Linear dynamic range was evaluated using matrix-matched calibration curves ranging 0.5–200 µg/kg, with each calibration level injected in triplicate. All target analytes demonstrated excellent linearity, with coefficients of determination (R²) &gt; 0.993, response factor (%RSD) values below 20% across the calibration range, and ion ratios (IRs) within ±30% of the average calibration standard values. System suitability for quantitative analysis was confirmed by calculated concentrations within ±20% of expected values and recoveries ranging from 96% to 104%. An example of calibration curve for Aldrin is shown in Figure 3.<h4>Conclusions&nbsp;</h4>The results obtained in these experiments demonstrate that the Orbitrap Exploris GC S mass spectrometer equipped with NeverVent AEI ion source represents a reliable tool for analysis of pesticides in complex matrices.&nbsp;<ul><li>The Orbitrap Exploris GC S offers a simple approach for the multiresidue analysis of pesticides allowing for full-scan acquisition combined with high mass resolving power&nbsp;</li><li>The NeverVent AEI ion source is designed for ultra-trace concentration detection, making it ideal for challenging applications ensuring detection limits at levels at or below 0.5 µg/kg for most of the investigated pesticides&nbsp;</li><li>Confident identification of compounds can be easily achieved through i). high spectral quality, ii). high spectral fidelity, ensuring consistent spectrum independently from concentration, and iii). consistent mass accuracy irrespectively of analyte concentration and time&nbsp;</li><li>System suitability for quantitative analysis was demonstrated with R2 &gt;0.993, RF %RSD across the entire calibration curve &lt; 20, and IRs within ± 30% of the average of calibration standards, calculated amounts within 20% the expected values, and percentage recovery (%) ranging from 96 to 104.</li></ul></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 28, 2026

Article

Product

Scientists

Presentation

Software

Poster

RECETOX (Research Centre for Toxic Compounds in the Environment) is an independent department of the Faculty of Science of Masaryk University in Brno, which has been established in 1983. RECETOX is focused on the research and education in cross-cutting area of Environment and Health. It addresses interactions among chemicals, environment, and biological systems, including consequences at local, regional, and global levels.

RECETOX - Centrum pro výzkum toxických látek v prostředí

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Wiley

Separation Science

Agilent Technologies

LECO

Thermo Fisher Scientific

Quantum Analytics

SelectScience

Waters Corporation

You might be facing challenges with respect to material identification process and its qualification.
Now, with Agilent&#39;s trusted solution - Vaya Raman Spectometer, confidently identify pharmaceutical materials and meet the performance specifications of global pharmacopoeia.
<blockquote>
Presenter: Rob WIlls (Molecular Spectroscopy Specialist, Agilent Technologies)
</blockquote>

Agilent Technologies: Raw Material ID and Raman

Raw Material ID and Raman

Challenges with respect to material identification process and its qualification.

The Cary 7000 UV-Vis-NIR system can be used to collect high quality data which can then be used to characterize optical coatings.
We will examine the techniques for determining film thickness, index of refraction, etc. through the use of a Cary 7000 UV-Vis-NIR system.
<blockquote>
Presenter: Mark Fisher, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Mark, an Application Scientist for Agilent Technologies, has over 35 years of experience in molecular spectroscopy. He has held roles in Agilent&#39;s UV-Vis-NIR, fluorescence, and atomic absorption product portfolios. In addition to identifying industry trends and new business needs, Mark&#39;s responsibilities include application development, pre and post-sales support, as well as acting as a customer advocate for new product and technology opportunities. Mark received his doctorate in analytical chemistry from the University of Nebraska-Lincoln.
</blockquote>

Agilent Technologies: Measuring and Analyzing Optical Coatings by UV-Vis-NIR

Measuring and Analyzing Optical Coatings by UV-Vis-NIR

Techniques for determining film thickness, index of refraction, etc. through the use of a Cary 7000 UV-Vis-NIR system.

Dear Orbitrap users,
We are pleased to invite you to our Autumn 2023 version of virtual activities to support our Compound Discoverer (CD) software users.
The workshops are designed to bring beginners up-to-speed with best practices as well as allow advanced users to interact with software experts and enquire how to get the most out of their data. Additionally, two dedicated sessions specialized in Metabolite/drug metabolite Identification (Met ID) and Gas Chromatography Mass Spectrometry (GCMS) data analysis will follow.
The content is delivered through online workshops, 2-3 hours each, via MS-Teams. The workshops feature live exercises on pre-distributed data, discussion of CD features, parameters, and optimized settings. The sessions are hands-on and highly interactive, so get the best experience by having CD 3.3 SP2 up and running. <a href="https://www.thermofisher.com/cz/en/home/industrial/mass-spectrometry/liquid-chromatography-mass-spectrometry-lc-ms/lc-ms-software/multi-omics-data-analysis/compound-discoverer-software.html">Click HERE</a> to download a free 60-day trial version of the latest Compound Discoverer software release.
The sessions allow ample time for the participants to get their CD-related questions answered in real time. The workshops will be taught in English, but participants can use MS Team`s instant subtitles in their preferred language.
<h5>General Compound Discoverer software training:</h5>
<ul>
<li>Tuesday 26th September: 10.00 - 13.30 CEST (Berlin time)</li>
<li>Wednesday 27th September: 10.00 - 13.30 CEST (Berlin time)</li>
<li>Thursday 28th September: 10.00 - 13.30 CEST (Berlin time)</li>
</ul>

Thermo Scientific: Compound Discoverer software workshops (General Compound Discoverer software training)

Compound Discoverer software workshops (General Compound Discoverer software training)

The workshops are designed to bring beginners up-to-speed with best practices as well as allow advanced users to interact with software experts.

General Compound Discoverer software training

With Services Central, you can spend less time searching for support and more time focusing on your important work. This online platform has what you need to easily manage your instruments and equipment.
<ul>
<li>Submit a service request at any time: you and your colleagues can request service 24/7†
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</li>
<li>Troubleshoot with ease: instantly access your service history or operating manuals to help diagnose and resolve simple instrument and equipment issues
</li>
<li>Make it your own: customize instruments and equipment with nicknames, add favorites, and create your own groups and systems
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Register for the free live webinar to see how Services Central expedites your service:
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<li>Learn tips and tricks to expedite your service process, including a live walkthrough of how to add your instruments and key features to help you in your daily work
</li>
<li>Hear how users are taking advantage of Services Central to help maximize uptime
</li>
<li>See what’s coming next
</li>
</ul>

Thermo Scientific: Services Central Webinar

Services Central Webinar

What you need to easily manage your instruments and equipment.

Thermo Scientific Services Central Webinar

In Quality Control laboratories, your work is the final critical testing step to ensure you have the necessary quality for your end customers.
As QC Scientists, you are faced with an ever-increasing workload, tasked with analyzing more samples in a shorter period of time and quickly turning around required reviews before batches can be released for shipment. The Empower Tip of the Week blog was started in 2017 with the focus on using Empower more effectively to help make your workflow in the laboratory more efficient. 
As we think about your workflow in Quality Control, we will highlight tips to make the following easier:
<ul>
<li>Getting started quickly: Comprehensive Sample Set Methods to prime, purge and equilibrate your instrument
</li>
<li>Triggers to stop you if there is a problem: Interactive System Suitability to automatically stop your instrument if system suitability fails
</li>
<li>Streamlining data review: Configure Review to automatically load and apply the Method Set for easier data review
</li>
<li>Streamlining result review: Review Results by Exception to flag out of specification Results
</li>
<li>Leveraging electronic workflows: Use Electronic Signatures on Report Methods
</li>
<li>Identify issues and ongoing monitor: Use Control Charts for data tracking and trending
</li>
</ul>
Please join us for a live discussion. As always, don’t forget to bring your questions for this exclusive opportunity to ask our experts anything about Empower Software!
<blockquote>
Presenter: Neil Lander (Principal Product Manager - Informatics Group, Waters Corporation)
</blockquote>
<blockquote>
Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager in Waters in the Informatics group. Neil provides internal support for Empower CDS software and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters Corporation, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.
</blockquote>

Waters Corporation: Empower Tips: Ask Me Anything About the Top Tips To Simplify Workflows and Your Day

Empower Tips: Ask Me Anything About the Top Tips To Simplify Workflows and Your Day

In Quality Control laboratories, your work is the final critical testing step to ensure you have the necessary quality for your end customers.

Empower Tips: Ask Me Anything About the Top Tips

Join us for this interactive panel discussion where laboratory professionals from across multiple markets and industries share success stories of how they navigated the journey to lab digitalization, from strategy and planning to implementation and optimization.
They will share lessons learned and best practices to best harness the power of digital technologies to improve efficiency, quality, and innovation in the lab.
Plus, you&#39;ll have the opportunity to engage with top managers from Agilent&#39;s lab digitalization team, who will share their expertise and insights on the latest trends, technologies, and best practices. They will provide an overview of Agilent&#39;s digital lab solutions and answer your questions about how to get the most out of your lab&#39;s transformation.
Key learning objectives
<ul>
<li>The benefits and challenges of lab digitalization, and how to overcome common obstacles
</li>
<li>Strategies for selecting and integrating the right digital solutions for your lab&#39;s unique needs
</li>
<li>Best practices for implementing and utilizing your digital lab environment
</li>
</ul>
Who should attend?
<ul>
<li>Laboratory Managers, laboratory directors, IT Managers, business IT, scientists, operations manager</li>
</ul>
<blockquote>
Presenter: Dr. Eliot Randle (SVP Digital Transformation, Digital Lab Consulting)
</blockquote>
<blockquote>
Dr. Eliot Randle is Senior Vice President of Digital Transformation Digital Lab Consulting (DLC). DLC is part of the ProPharma Group and provides independent strategic and business consulting to help organisations to transform their business through better use of data and technology.
</blockquote>
<blockquote>
Presenter: Eric Kemp (IT Manager, Modern Canna)
</blockquote>
<blockquote>
Eric Kemp is a seasoned professional with 15+ years of experience in IT and Analytical Chemistry. He has held diverse roles such as Lab Tech, Analyst, Systems Administrator, Entrepreneur, QA Manager, and IT Manager since 2008. In 2012, Eric founded an IT consulting business specializing in Laboratory Information Management Systems (LIMS) re-implementation for Florida markets. Joining Modern Canna in 2018, Eric has contributed expertise to drive innovation and efficiency in both fields. With a unique perspective at the intersection of IT and Analytical Chemistry, Eric brings valuable insights to the cannabis testing industry.
</blockquote>
<blockquote>
Presenter: Tony McKeown (LIMS Administrator, doTERRA Global)
</blockquote>
<blockquote>
Tony McKeown, from Cobh, County Cork, Ireland, is a highly accomplished individual with a strong background in IT. He graduated from Munster Technological University with a degree in IT and then embarked on a successful 12-year self-employment journey. In September 2021, Tony joined doTERRA Global, based in Blarney, Co Cork, Ireland, where he played a pivotal role in the organization&#39;s digital transformation initiative.
</blockquote>
<blockquote>
Tony&#39;s primary responsibility at doTERRA Global was to identify and implement a Laboratory Information Management System (LIMS) for its onsite laboratories. Leveraging his expertise and knowledge, he successfully sourced and introduced Agilent SLIMS in May 2023, marking a significant milestone in the company&#39;s digitalization journey.
</blockquote>
<blockquote>
Beyond his profession, Tony is an avid sports fan, and has a keen interest in politics and current affairs.
</blockquote>
<blockquote>
Presenter: Jean-Guillaume Baumann (Senior Product Marketing Manager, Digital Lab, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Jean-Guillaume joined Agilent Technologies in 2018 through the acquisition of Genohm as a Business Development Manager. Holding a Master’ degree in Mathematics, he graduated in 2015 from the University of Neuchâtel with a Master’s degree with honors in Mathematics with a specialization in computer science. Passionate about the business side also, he studies for an EMBA at University of Lausanne.
</blockquote>
<blockquote>
Presenter: Dr. Thomas Schmidt (Marketing Director, Digital Solutions, Software &amp; Informatics Division)
</blockquote>
<blockquote>
Thomas Schmidt is Marketing Director for Digital Solutions in the Software &amp; Informatics Division at Agilent Technologies. Originally a chemist by training, he conceptualized and managed multiple Laboratory Informatics solutions during his career covering all aspects of the laboratory operation, including workflow management, data management, sample management, instrument control, and laboratory execution systems. Thomas is a passionate ambassador for the Digital Laboratory.
</blockquote>
<blockquote>
Presenter: Dora Wells (Editorial Team, SelectScience)
</blockquote>
<blockquote>
Dora studied biomedical science at the University of Manchester, UK, and as a member of the editorial team, plays an integral role in helping to shape the content on SelectScience.
</blockquote>

LabRulez/AI: From Paper to Pixels: Success stories of laboratories embracing digitalization

From Paper to Pixels: Success stories of laboratories embracing digitalization

Success stories of how they navigated the journey to lab digitalization, from strategy and planning to implementation and optimization.

Success stories of laboratories embracing digitalization

Every organization has unique needs regarding their laboratory processes, workflows, and overall mission.
When considering ways to meet those needs, it is vital that an organization evaluates the potential resources they can implement, from laboratory instrumentation to software solutions. The goal is to add value and increase optimization. 
Selecting a software solution is a decision that will have a direct, intense impact on your lab. It will affect how efficiently your staff works, how streamlined your processes are, and how accurately your work can be accomplished. You want to make sure that the impact is positive. A laboratory information management system (LIMS) is a necessary resource because it can store and aggregate your data in one place, streamline your workflows and processes, and increase efficiency, reliability, and value – all which are limited when managed manually. It’s important to choose a solution that is easy-to-use, with minimal customization that addresses the key challenges of your industry and can integrate with existing instrumentation and software systems. Understand the key considerations when selecting a LIMS to best meet your goals and elevate your lab.
By attending this presentation you will learn about:
<ul>
<li>The value of choosing a LIMS solution that meets your laboratory’s requirements and needs
</li>
<li>The impact of making the right choice to elevate your lab’s productivity, efficiency, and ability to deliver high quality results
</li>
</ul>
<blockquote>
Presenter: Adam Collins (Senior Product Specialist, Digital Science Solutions, Thermo Fisher Scientific)
</blockquote>
<blockquote>
As Senior Product Specialist for Digital Science Solutions at Thermo Fisher Scientific, Adam specializes in providing software demonstrations and technical support for organizations across multiple industry sectors who are assessing Thermo Fisher Scientific’s LIMS solutions for their laboratory needs. He has over five years of experience as a technical product specialist for laboratory software. Adam has Doctor of Philosophy and Bachelor of Science degrees in Microbial Genetics and Microbiology from the University of Nottingham.
</blockquote>

Separation Science: How to choose the right LIMS solution

How to choose the right LIMS solution

Understand the key considerations when selecting a LIMS to best meet your goals and elevate your lab.

In the ever-evolving landscape of today&#39;s competitive market, the significance of maintaining the quality and safeguarding the integrity of your brands cannot be overstated.
It is becoming even more imperative to outpace your competitors by leveraging powerful technology which can enhance your workflows, elevate brand quality and empower your Aroma, Flavour and Fragrance analysis.
In this webinar, we explore the capabilities of LECO technology and the impact it is having on overcoming the challenges faced in the Aroma, Flavor, and Fragrance industry.
<h4>1. Enhanced Workflows for Essential Oils: Increase Confidence in QC Screening &amp; Characterisation</h4>
<ul>
<li>Presented by Sebastiano Panto
</li>
<li>Hydrogen Carrier Gas
</li>
<li>BT 1D GC-TOFMS
</li>
<li>Maximise efficiency with Sync Software
</li>
</ul>
<h4>2. Investigate Perfumes in Greater Depth &amp; Faster: Utilise GCxGC to characterise perfume complexity and understand important differences for both performance and quality assurance</h4>
<ul>
<li>Presented by Lena Dubois
</li>
<li>Unveiling the power of BT4D and GCxGC-TOFMS
</li>
<li>Distinguishing real from counterfeit perfumes
</li>
<li>Seamlessly navigate complexity with Tile Software
</li>
<li>Allergen analysis to ensure safety
</li>
</ul>
<h4>3. Non-Target Characterization and Simultaneous Quantitation for Reformulation of Complex Fragrance Samples with GCxGC-MS/FID</h4>
<ul>
<li>Presented by Dr. Liz Humston-Fuller
</li>
<li>Mastering BT4D, RFF, Splitter/FID technologies
</li>
<li>Characterisation in detail
</li>
<li>Confident quantification through enhanced FOD accuracy
</li>
</ul>
<h4>4. Whisky Analysis: Unravel the complexities and differences of Whiskies</h4>
<ul>
<li>Presented by Taff Morgan (The Open University)
</li>
<li>BT 1D/BT4D
</li>
<li>Complex characterisation
</li>
<li>Comparison of different origins and process types
</li>
<li>Fast interpretation of large sample sets with Sync/Tile
</li>
</ul>
By immersing yourself in these advanced technologies and software solutions, you stand to revolutionize your workflow, elevate quality control measures, protect your supply chain, uphold brand reputation, ensure product safety, and shape consumer perception.
<blockquote>
Presenter: (Alan Griffiths, Director of Separation Science Global Sales, LECO USA)
</blockquote>
<blockquote>
Initially joining LECO UK as an installation and service engineer 15 years ago before taking on the challenges of sales across the UK and Ireland territory, Alan has a vast experience and understanding of LECO’s separation science portfolio. In the webinar, Alan will both introduce the speakers and chair the Q&amp;A.
</blockquote>
<blockquote>
Presenter: (Dr. Liz Humston-Fuller, Applications Chemist, LECO USA)
</blockquote>
<blockquote>
Liz earned her PhD in Analytical Chemistry with Prof Robert Synovec in the group that developed the tile-based Fischer ratio algorithms that have been further developed in collaboration with LECO to underpin ChromaTOF Tile. Her presentation will introduce “Advanced processing software with ChromaTOF Tile &amp; ChromaTOF Sync.”
</blockquote>
<blockquote>
Presenter: (Dr. Lena Dubois, Applications Chemist, LECO Europe)
</blockquote>
<blockquote>
Lena has ten years’ experience in the field of application chemistry and gained her PhD under the mentorship of Prof. Jef Focant at Liège University. Lena will be discussing “Workflows for the assessment of key aroma compounds” by utilising the latest in advanced GC and GCxGC -TOFMS and data processing technologies.
</blockquote>
<blockquote>
Presenter: (Dr. Geraint (Taff) Morgan, Department of Physical Sciences, The Open University)
</blockquote>
<blockquote>
Taff is an analytical chemist with vast experience, applying his knowledge from the bottom of the ocean to the surface of a comet. His talk entitled “Comprehensive Evaluation of Scotch Whisky Aroma Profile Using SPME-GCxGC-TOFMS” will demonstrate the effective use of high-quality instrumentation and software to real world whisky samples.
</blockquote>

LECO: State of the Art Technology for Aroma, Flavour and Fragrance Analysis

State of the Art Technology for Aroma, Flavour and Fragrance Analysis

Explore the capabilities of LECO technology and the impact it is having on overcoming the challenges faced in the Aroma, Flavor, and Fragrance industry.

Technology for Aroma, Flavour and Fragrance Analysis

As our understanding of the human impact on the environment deepens, so too does the conversation and action surrounding two linked topics: how companies can adopt more sustainable operations and which other compounds necessitate monitoring to address the latest safety and environmental concerns.
When trying to assess sustainability in a GC-based lab, organic solvents, liquid cryogen and helium are often at the top of lab managers&#39; lists to reduce. Hydrogen carrier gas, solvent-free, and cryogen-free sample introduction methods offer a solution to these problems. However, are they compatible with the expanding number of species and lower detection limits now required for many organic compound monitoring lists?
In this webinar, Hannah Calder, Environmental Air – Market Development Manager at Markes International, and Dr. Aaron Davies, Commercial Marketing Manager – Thermal Desorption at Markes International, will discuss case studies where air monitoring lists are growing in complexity, such as in ozone precursor monitoring, air toxics, and organic ozone-depleting substances. In each case study, as well as looking at how the methodology can meet the requirements of monitoring, they will also discuss how the method can be made more sustainable, ensuring longevity and accountability.
By attending this webinar, you will learn:
<ul>
<li>About proposed changes to monitoring of ozone precursors in Europe, air toxics in the USA and ozone depleting substances in China
</li>
<li>How sustainability can be introduced into laboratories analysing organic compounds, with a focus on air monitoring
</li>
<li>What the challenges are when adopting a more sustainable approach, and tools available to help facilitate the conversion process
</li>
</ul>
Who should attend?
<ul>
<li>Researchers interested in monitoring of organic compounds
</li>
<li>Laboratory and project managers specialising in air samples
</li>
<li>Environmental consultants
</li>
</ul>
<blockquote>
Presenter: Hannah Calder (Markes International)
</blockquote>
<blockquote>
Hannah Calder is Markes International’s Environmental Air Market Development Manager, specialising inthe application of thermal desorption in environmental air monitoring. Hannahjoined Markes International’s global team of technical experts in 2013 followingher master’s degree in chemistry obtained from Cardiff University. Hannah is involved withdevelopment of international analytical standards for ambient and indoor airmonitoring through ASTM committee D22 and CEN committees TC264 and TC351. Shehas a comprehensive knowledge on the use of Thermal Desorption as an analyticaltool for air analysis and has recently worked on projects for monitoring ozonedepleting substances, ozone precursors, air toxics and PFAS.
</blockquote>
<blockquote>
Presenter: Dr. Aaron Davies (Markes International)
</blockquote>
<blockquote>
Aaron Davies is the commercial marketing manager for thermal desorption at Markes International. After graduating from Cardiff and Monash Universities with a PhDin Chemistry, Aaron has worked in industry as a Process and Product DevelopmentChemist, GC, GC-MS Product Specialist before finally focusing on his passionfor thermal desorption. In his role, Aaron assists customers and partners onthe effective use of thermal desorption for simplifying sample preparation andthe benefits of using alternative carrier gases (such as hydrogen and nitrogen)to helium.
</blockquote>
<blockquote>
Presenter: Ellen Simms (Assistant Editor, SelectScience)
</blockquote>
<blockquote>
Ellen studied biological sciences at the University of the West of England, UK, before completing a master&#39;s in epidemiology from the University of Bristol. As a member of the Editorial team, she now plays an integral role in shaping the content on SelectScience.
</blockquote>

SelectScience: Balancing lab sustainability and expanding VOC monitoring requirements for air analysis

Balancing lab sustainability and expanding VOC monitoring requirements for air analysis

Case studies where air monitoring lists are growing in complexity, such as in ozone precursor monitoring, air toxics, and organic ozone-depleting substances.

VOC monitoring requirements for air analysis

Learn how GC-based techniques widely used in VOC monitoring can be easily applied to PFAS analysis.
Exposure to per- and polyfluoroalkyl substances (PFAS) can occur through a number of pathways. One of the less understood, but equally important, routes is air. The movement of PFAS through air can happen relatively unimpeded when compared to water and soil, and deposition from the air is another way that they can become contaminated.
Sources of PFAS in the air can be industrial activity, disposal of PFAS containing materials or simply emissions from PFAS containing products. Monitoring of these different environments and matrices is commonly carried out using GC based techniques for other VOCs, so how does monitoring of PFAS differ? Join this webinar to hear about how techniques already broadly used for VOC monitoring can be successfully applied to PFAS measurements from air and materials.
By attending this webinar, you will learn:
<ul>
<li>Which PFAS are GC amenable and which make most sense to monitor with other techniques
</li>
<li>How current VOC monitoring standards can be applied to PFAS monitoring in air
</li>
<li>What changes to those methods mean in terms of performance and new challenges they introduce
</li>
<li>What detection limits are possible in air and what is needed for different environments and matrices
</li>
</ul>
<blockquote>
Presenter: Hannah Calder (Environmental Air Market Development Manager, Markes International)
</blockquote>
<blockquote>
Hannah Calder is Markes International’s Environmental Air Market Development Manager, specialising in the application of thermal desorption in environmental air monitoring. Hannah joined Markes International’s global team of technical experts in 2013 following her Masters degree in Chemistry obtained from Cardiff University. Hannah is involved with development of international analytical standards for ambient and indoor air monitoring through ASTM committee D22 and CEN committees TC264 and TC351. She has a comprehensive knowledge on the use of Thermal Desorption as an analytical tool for air analysis and is currently working on projects for monitoring ozone depleting substances, air toxics, ozone precursors, and PFAS.
</blockquote>

Quantum Analytics: Adapting GC-Based Standards for Sampling & Analysis of PFAS in Air

Adapting GC-Based Standards for Sampling & Analysis of PFAS in Air

Learn how GC-based techniques widely used in VOC monitoring can be easily applied to PFAS analysis.