In this technical tip from Phenomenex, the topic of gas chromatography (GC) column trimming is addressed from a troubleshooting perspective. The key question explored is whether trimming a GC column is necessary and how it impacts chromatographic performance.<h3>Why Trim a GC Column?</h3>Column trimming is primarily used to restore chromatographic performance by removing damaged or contaminated sections, typically located at the column inlet.<h5>1. Baseline Bleed, Noise, Ghost Peaks, Poor Peak Shape</h5><ul><li>Cause: Column contamination</li><li>Removing the contaminated stationary phase at the column entrance helps restore performance.</li></ul><h5>2. Elevated Baseline (Especially at High Temperature)</h5><ul><li>Cause: Column bleed</li><li>Degradation of the stationary phase due to oxygen exposure or thermal damage leads to increased baseline.</li></ul><h5>3. Ghost Peaks (Peaks Without Injection)</h5><ul><li>Cause: Residual sample or contamination</li><li>Compounds trapped at the beginning of the column can appear as peaks even when no sample is injected.</li></ul><h5>4. Peak Tailing (Asymmetrical Peaks)</h5><ul><li>Cause: Damaged or contaminated column sections</li><li>These issues result in adsorption effects or poor flow dynamics.</li></ul><h5>5. Retention Time Shifts</h5><ul><li>Cause: Contamination or damage near the inlet</li><li>Although trimming slightly changes retention time, it can correct shifts caused by inlet-side issues.</li></ul><h5>6. Baseline Noise and Spikes</h5><ul><li>Cause: Particulate matter or degraded stationary phase</li><li>These can lead to detector instability and random signal fluctuations.</li></ul><h5>7. Baseline Drift or Wander</h5><ul><li>Cause: Contamination or oxidized column sections</li><li>Removing these regions stabilizes the baseline.</li></ul><h5>8. Loss of Resolution or Sensitivity</h5><ul><li>Cause: General column degradation</li><li>Trimming removes the most exposed and damaged portions, effectively rejuvenating column performance.</li></ul><h3>How to Trim a GC Column</h3>A capillary GC column consists of:<ul><li>Polyimide outer coating (protective layer)</li><li>Fused silica tubing (fragile but flexible core)</li></ul><h3>Step-by-Step Procedure</h3><h5>1. Scoring the Column</h5><ul><li>Use a ceramic wafer</li><li>Hold it at an inclined angle</li><li>Score the polyimide coating perpendicular to the column</li></ul><h5>2. Breaking the Column</h5><ul><li>Perform a quick, decisive flick</li><li>This ensures a clean, square cut</li></ul><h5>3. Inspecting the Cut</h5>After trimming, visually inspect the column end.<h3>Examples of Column Cuts</h3><h4>Good Cut</h4><ul><li>Clean, square end</li><li>Ensures proper sealing and connection</li></ul><h5>Bad Cuts</h5><ul><li>Slight Irregularity<ul><li>Small imperfection at the edge</li><li>Can cause leaks and active sites</li></ul></li><li>Poor / Rough Cuts<ul><li>Uneven or jagged edges</li><li>Lead to:<ul><li>Poor connections</li><li>Active sites</li><li>Peak tailing</li></ul></li></ul></li></ul><h2>Conclusion</h2>Trimming a GC column is a simple yet effective troubleshooting step. By removing contaminated or damaged sections—especially near the inlet—it can resolve a wide range of chromatographic issues, including baseline instability, ghost peaks, and loss of performance.Proper cutting technique is essential to avoid introducing new problems such as leaks or active sites.

Trimming a GC Column: Purpose, Symptoms, and Proper Technique

<h3>We're excited to announce that <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity Chromatography Software</a> version 10.1.2 is now available!</h3>This minor update expands Clarity’s portfolio with new control modules.<h4>Newly added Instrument control modules</h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4>Updated Instrument control modules</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168">Ecom</a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328">Knauer</a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1">Changelog</a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622">Clarity 10.1 release highlights</a>.Clarity can control 1000+ instruments; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls">list can be previewed here</a>.</blockquote><h4>Supported Instruments in Clarity (DataApex) — Quick Guide</h4>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via digital control (DD) and analog acquisition (A/D) using the Colibrick module.<h5>Gas Chromatographs (GC)</h5>Digital integration over LAN/RS232 (many via ICF):<ul><li>Agilent: 5890, 6890, 7890, 8860, 8890, Intuvo 9000</li><li>Shimadzu: GC-2010/2014, Nexis GC-2030</li><li>Thermo Fisher: TRACE 1300/1310</li><li>PerkinElmer: Clarus 400–690</li><li>Also supported: Dani, Ellutia, Young In Chromass, Apix, Fuli, GOW-MAC (selected models)</li></ul><blockquote>Note: Most Agilent 6890–8890 and Intuvo use LAN – ICF.</blockquote><h5>HPLC Systems</h5>Full system/module control:<ul><li>Agilent 1100–1290 Infinity II (ICF)</li><li>Shimadzu LC-10/20 and Nexera LC-40</li><li>PerkinElmer Flexar / NexSAR</li><li>Knauer Azura / BlueShadow / Smartline</li><li>Hitachi Chromaster / Primaide</li><li>Young In Chromass ChroZen series</li><li>Sykam S500–S600, Watrex Streamline, Hanon LC7000–7300</li></ul><h5>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</h5><ul><li>Pumps: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li>Detectors: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li>Column Ovens: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li>Fraction Collectors: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5>Autosamplers</h5><ul><li>Agilent GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li>Shimadzu AOC-20 / AOC-5000+, SIL-10 / SIL-20 / SIL-40 series</li><li>CTC Analytics PAL, HTA autosamplers, Spark Alias/UHPLC, Knauer AS 6.1L</li><li>PerkinElmer Flexar / NexSAR AS</li></ul><h5>Other Devices</h5><ul><li>GC×GC modulators (e.g., Charles University GC×GC Modulator)</li><li>Valves &amp; switch modules (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li>Degassers, flow monitors, managers, interfaces</li><li>LC-MS / GC-MS: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li>Balances (EA extension): Mettler Toledo, Sartorius</li></ul><h5>Analog Acquisition (Colibrick)</h5>A/D support for legacy or analog-output devices:<ul><li>GC: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li>HPLC Detectors: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li>Elemental &amp; Amino Acid Analyzers: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul>If you are interested in a DEMO VERSION, contact us!

DataApex Clarity Chromatography software 10.1.2 just released!

🎤Jessica WhitehouseHaloacetic acids (HAAs) are disinfection byproducts formed when chlorine or bromine reacts with organic matter in water—and some are linked to serious health concerns. In this episode of Concentrating on Chromatography, we sit down with Jessica Whitehouse, MSc student at the University of Calgary, to discuss how she developed a GC-MS method to detect and quantify HAAs in real-world water samples.During her undergraduate research at Thompson Rivers University, Jessica tackled a major challenge faced by many academic labs: how to analyze regulated environmental contaminants without access to GC-ECD instrumentation. &nbsp;Using dispersive liquid–liquid microextraction, derivatization, and GC-MS, she built a faster, more accessible workflow—and applied it to tap water, swimming pools, and hot tubs.<h4>In this conversation, we cover:</h4><ul><li>What haloacetic acids are and why they matter</li><li>Why standard EPA methods can be difficult for smaller or teaching-focused labs</li><li>How GC-MS can be adapted for HAA analysis</li><li>The challenges of derivatization and temperature program optimization</li><li>Unexpected findings in brominated vs. chlorinated HAAs</li><li>Why pool and hot tub water can show surprisingly high HAA levels</li><li>The excitement (and frustration) of first-time method development</li><li>Advice for undergraduate and early-career analytical chemists</li></ul>Jessica also shares how this project led directly to her current MSc research on ozone and nanobubble water disinfection, where she’s now expanding into ion chromatography.Whether you work in environmental analysis, chromatography, GC-MS, or are just starting your journey in analytical chemistry, this episode offers practical insight into real lab constraints, method development, and the joy of finding your first analyte peak.<h3>Video Transcription</h3><h4>Introduction</h4>Haloacetic acids (HAAs) are an important class of disinfectant byproducts formed when organic matter present in water reacts with chemical sanitizers. Because several HAAs are associated with adverse health effects, their determination remains relevant in environmental and public health analysis. This interview highlights the academic pathway and research experience of Jessica, whose undergraduate work focused on the development of a gas chromatography–mass spectrometry (GC-MS) method for the analysis of HAAs in pool and hot tub water.Her project emerged from a combination of academic interest in analytical chemistry, practical experience with water testing, and the constraints of instrument availability in an undergraduate research setting. The resulting workflow illustrates how method adaptation, critical problem-solving, and persistence can enable meaningful analytical research even when standardized methods are not directly accessible.<h4>Academic Background and Entry into Analytical Chemistry</h4>Jessica completed a Bachelor of Science in Chemistry with a minor in Physics at Thompson Rivers University in British Columbia. Her interest in analytical chemistry developed during her second year of study, when coursework revealed the quantitative and detail-oriented nature of the discipline. This emphasis on numerical interpretation, precision, and method development aligned strongly with her academic strengths and motivated her to pursue analytical research.Her specific interest in water chemistry originated even earlier through practical work in a pool and hot tub store, where she became familiar with routine water testing and the chemical factors influencing water quality. This early exposure led naturally into undergraduate research under the supervision of Dr. Sharon Brewer, whose expertise in water analysis provided an ideal foundation for the project.<h4>Haloacetic Acids as Disinfectant Byproducts</h4>Haloacetic acids are a subset of disinfectant byproducts generated when sanitizing agents react with natural organic matter in water. In treated recreational water systems such as pools and hot tubs, disinfectants are essential for microbial control, yet they can also lead to formation of unwanted chemical byproducts. Because some HAAs are considered potentially harmful, their occurrence and concentration warrant analytical attention.In this study, both chlorinated and brominated HAAs were of interest. Although the tested water systems were primarily sanitized using chlorine-based products, the occurrence of brominated HAAs emerged as a notable and somewhat unexpected finding.<h4>Analytical Challenges and Method Selection</h4>A major challenge in the project was the lack of access to the instrumentation required for the standard EPA-based method initially considered for HAA analysis. The available protocol depended on GC-ECD instrumentation, which was not accessible at the university. This limitation required the development of an alternative strategy based on the instruments available locally.GC-MS was selected as the most practical analytical platform. To support this approach, Jessica identified a literature source describing a similar method that could be adapted to her research aims. In parallel, dispersive liquid–liquid microextraction was introduced into the workflow as a means of sample preparation, providing valuable methodological experience beyond the standard undergraduate laboratory curriculum.This adaptation illustrates a common reality in academic research: analytical methodology is often shaped not only by ideal regulatory procedures, but also by local instrument access, scheduling limitations, and the practical needs of the researcher.<h4>Need for Derivatization in GC-MS Analysis</h4>A central analytical issue was that HAAs are inherently nonvolatile, which makes them poorly suited to direct GC analysis. To enable gas chromatographic separation, derivatization was required to convert the analytes into more volatile derivatives with more favorable boiling characteristics.In this method, derivatization with octanol was employed. This modification improved volatility and also generated larger fragments, which aided mass spectral interpretation by making the analyte fragmentation patterns easier to distinguish. Thus, derivatization served both chromatographic and mass spectrometric purposes.<h4>Optimization of the GC Temperature Program</h4>Considerable effort was devoted to optimization of the GC temperature program. The main difficulty did not arise solely from the analytes themselves, but from the derivatization reagent. Octanol produced a broad and persistent chromatographic feature, including a significant shoulder extending into later retention times. This complicated separation and increased pressure to keep the method sufficiently short for routine sample throughput.Among the analytes, monochloroacetic acid proved especially problematic. Because it differed only subtly in structure and produced overlapping behavior relative to the octanol-derived background, its signal was difficult to isolate confidently. Although chlorine-containing fragments could be observed, precise assignment remained challenging. This difficulty underscores how small structural differences and matrix-related interferences can complicate quantitative GC-MS workflows.<h4>Method Performance and Practical Advantages</h4>Although the adapted GC-MS method was developed out of necessity, it also provided practical advantages over the more standardized workflow that had initially been considered. In particular, the derivatization step in the adapted approach required only approximately 10 minutes, whereas the more conventional procedure involved a water bath step lasting around two hours. In addition, the adapted workflow offered shorter overall preparation and analysis timing, allowing batches of samples to be prepared and placed on the autosampler within a normal working schedule.From a practical research perspective, this translated into substantially improved laboratory efficiency. The ability to complete derivatization quickly and begin automated sample analysis without extensive delays made the workflow more manageable and better suited to the demands of an undergraduate project.<h4>Unexpected Findings: Brominated HAAs in Chlorine-Sanitized Systems</h4>One of the more surprising outcomes of the study was the predominance of brominated HAAs, despite the fact that the investigated pools and hot tubs were sanitized using chlorine-based treatments. Four of the systems relied on sodium chloride electrolysis to generate chlorine species, while others used chlorine-containing puck formulations commonly applied in recreational water treatment.Given these conditions, higher levels of chlorinated HAAs might have been expected. Instead, the results suggested a greater abundance of brominated HAAs. A plausible explanation is the presence of bromine-containing impurities in commercial pool and hot tub chemicals. Although such impurities may occur at relatively low levels, they can still influence disinfectant byproduct formation. The observation highlights the importance of considering the full chemical composition of treatment products, not merely their primary declared active ingredients.<h4>Value of Practical Industry Experience</h4>Jessica’s prior work in the pool and hot tub industry provided an unusually strong contextual advantage for the project. Because the samples originated from store clients, she had access to detailed information about the chemicals used in each system, including safety data sheets and knowledge of treatment timing. This background significantly strengthened interpretation of the analytical results by linking measured byproducts to known product usage patterns.Such integration of practical field knowledge with laboratory analysis represents an important strength in applied environmental chemistry, particularly when studying real-world water systems rather than idealized laboratory samples.<h4>Scientific Development and Early Research Motivation</h4>An especially valuable element of the project was the role it played in building research confidence. Jessica described the first successful identification of an analyte peak as a memorable turning point, reflecting the emotional significance of early experimental success in scientific training. In analytical chemistry, where method optimization often involves repeated setbacks and ambiguous data, such moments can be critical in sustaining motivation and reinforcing scientific identity.This experience also informed her advice to early-stage researchers: unfavorable or unexpected outcomes still constitute valid results. Negative or imperfect findings remain analytically meaningful and contribute to scientific understanding, provided they are interpreted carefully.<h4>Connection to Current Research</h4>Jessica is now working at the University of Calgary on a different project focused on ozone and nanobubble disinfection. Although the analytical platform and immediate research questions have changed, the conceptual connection to her earlier work remains clear. Her experience with disinfectant byproducts and water chemistry directly supported her transition into this new role and helped position her as a strong candidate for research in water treatment-related systems.She also expressed interest in expanding her analytical expertise through ion chromatography, which will play a role in her current work. This transition reflects the broader development of an environmental analytical chemist whose work continues to center on water quality, disinfection chemistry, and the analytical tools needed to investigate both.<h4>Public Health Relevance</h4>A notable practical implication of the project concerns recreational water safety. Jessica emphasized that pool and hot tub water should not be ingested, a recommendation already widely understood in general terms but further reinforced by her findings. In at least one case, HAA concentrations were reported at levels far above the federal drinking water regulation threshold. While such regulations are designed for potable water rather than recreational water, the comparison nevertheless illustrates the extent to which disinfectant byproducts may accumulate in these environments.She also noted that several HAAs are classified as probable human carcinogens, with prolonged exposure linked to serious health concerns. Although occasional accidental ingestion is not equivalent to chronic exposure, the findings reinforce the importance of appropriate hygiene, safe water maintenance practices, and awareness of chemical byproduct formation in recreational systems.<h4>Conclusion</h4>This research demonstrates how meaningful analytical chemistry can emerge from a combination of scientific curiosity, practical constraints, and strong mentorship. By adapting a GC-MS workflow for the determination of haloacetic acids in pool and hot tub water, Jessica developed a method that was both workable within local instrument limitations and efficient enough to offer practical benefits over more conventional procedures.Beyond the analytical results themselves, the project highlights several broader themes: the value of undergraduate research, the importance of flexibility in method development, the benefit of practical contextual knowledge, and the relevance of environmental analytical chemistry to real-world public health questions. It also shows how early research experiences can shape a long-term scientific trajectory, leading from undergraduate investigation to continued work in water chemistry and disinfection science.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Detecting Haloacetic Acids in Water with GC-MS

Article

Product

Academy

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Scientists

Interview

Science and research

Software

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

Phenomenex

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Separation Science

Agilent Technologies

Thermo Fisher Scientific

VWR/Avantor

Have you been wondering how the new features in the 8890 can help your lab? Do you know the new features the 8890 has to offer?
The 8890 has integrated tools that can help your lab with productivity. The new tools can also help your lab maintain, troubleshoot, and monitor your GC’s usage. Join this webinar to learn more about these features and find out how you can implement them in your lab.
<blockquote>
Presenter: Jamie Wetuski
</blockquote>

Agilent Technologies: Agilent 8890 Features to Improve Lab Productivity

Agilent 8890 Features to Improve Lab Productivity

Have you been wondering how the new features in the 8890 can help your lab? Do you know the new features the 8890 has to offer?

As you face the constant pressure to analyze more samples, even as resources shrink and analytical challenges grow, new developments in intelligence and operations raise the gold standard in GC/MS to handle the complexity and demands of routine testing.
In this webinar, the speakers will focus on technology advancements and best practices in GC/MS that reduce downtime and optimize lab productivity. Specifically, the discussion will highlight overcoming current helium shortage challenges without compromising system uptime. Future-proof your lab with Agilent’s additions to its GC/MS portfolio that allow you to transform would-be obstacles into opportunities with intelligent instruments, familiar software and a continuing legacy of innovation and performance.
<h5>By attending this presentation you will learn about improving lab productivity, operating costs and sustainability by:</h5>
<ul>
<li>Adopting next-generation/in-built GC &amp; GC/MS Intelligence</li>
<li>Preventing disruptions due to helium shortages</li>
<li>Reducing GC/MS maintenance frequency</li>
<li>Confidently addressing new regulations and application needs</li>
<li>Making informed, sustainable decisions with ACT labeling</li>
</ul>
PLUS - Participation Bonus: Attend the webinar to receive a special offer from Agilent.
<blockquote>
Presenter: Lakshmi Krishnan (GC/MS Single Quadrupole Product Manager, Agilent Technologies)
</blockquote>
<blockquote>
Lakshmi Krishnan is the GCMS Single Quadrupole Product Manager in the Mass Spectrometry division of Agilent Technologies, located in Santa Clara, California. Lakshmi obtained her M.S. in Biotechnology, focusing on Business Administration, from San Jose State University. At Agilent, she works on new product introductions, marketing and commercialization of GC/MSD platforms.
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<blockquote>
Presenter: Joel Ferrer (GC/MS Triple Quadrupole Product Manager, Agilent Technologies)
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Joel Ferrer is the Product Manager for the Agilent Triple Quadrupole GC/MS portfolio. He obtained his B.S. in Biomedical Sciences at Texas A&amp;M University where he gained experience on Agilent LC/MS and GC/MS instrumentation performing metabolomics research in the Department of Chemistry. Joel later earned his MBA from the University of Houston with a focus on Product Management and Marketing Analytics. He’s been with Agilent for over 5 years and in his current product management role since June 2020.
</blockquote>

Separation Science: Keep Running, Take the Lead: Integrated, Intuitive, GC & GC/MS Intelligence

Keep Running, Take the Lead: Integrated, Intuitive, GC & GC/MS Intelligence

A webinar focusing on new technology advancements and best practices in GC/MS that reduce downtime and enhance lab productivity and performance.

Integrated, Intuitive, GC & GC/MS Intelligence

Traditional analytical workflows often involve sample preparation techniques requiring the use of large volumes of raw samples and organic solvents. The goal is to drive up recovery and sensitivity as it pertains to obtaining low levels of analyte detection.
Modern SPE technology has emerged to minimize sample and solvent consumption, while providing analytical sensitivity that is comparable to traditional workflows. The Biotage® MIKRO plate incorporates a common 96-well plate format for high throughput analysis and a robust, loosely packed 2 mg polymeric sorbent for the extraction of a variety of analytes.
Presented here is a brief overview of common but essential workflows in a microelution format, fully automated on the Biotage® Extrahera LV-200 sample preparation instrument. Workflows are simple, cost effective, and include discussions of drugs of abuse, steroids, catecholamines, and metanephrines.
<h5>Attendees will:</h5>
<ul>
<li>learn the unique differences between microelution and conventional SPE</li>
<li>better understand the application benefits of Mikro SPE</li>
<li>learn how to troubleshoot to improve analyte recovery</li>
<li>gain a direct comparison of the performance of traditional SPE workflow vs Mikro SPE automated workflow</li>
</ul>
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Presenter: Amber Cain (Application Scientist, Biotage)
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Amber has 10 years of experience, largely involved in contract research organization work from bioanalytical pharmaceutical testing and metabolomics. She has extensive experience with SPE and other sample preparation techniques as well as LC-MS/MS.
</blockquote>

SeparationScience: The Might of MIKRO: Rethinking Routine Analytical Workflows through Volume Reduction and Solvent Consumption

The Might of MIKRO: Rethinking Routine Analytical Workflows through Volume Reduction and Solvent Consumption

An overview of common but essential workflows in a microelution format, fully automated on the Biotage® Extrahera LV-200 sample preparation instrument.

Analytical Workf. - Volume Reduction and Solvent Consumption

Simple microplastic workflows will be discussed, featuring the 8700 LDIR and Cary 630.
<blockquote>
Presenter: Louis Tisinger, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)
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Louis (Lou) Tisinger has a Ph.D. in Analytical Chemistry from Miami University in Oxford Ohio, where his graduate research involved the study of ATR imaging and microscope performance in vibrational spectroscopy. Most of his career has been related to pre- and post-sales support of FTIR spectrometers, microscopes, imaging systems, and thermal analytical instruments, focusing on analyzing customer samples, demonstrations, post-sales training, troubleshooting, and R&amp;D.
</blockquote>

Agilent Technologies: Analysis of Microplastics Has Never Been Easier

Analysis of Microplastics Has Never Been Easier

Simple microplastic workflows will be discussed, featuring the 8700 LDIR and Cary 630.

During this webinar we will take a look at some of the latest trends and hot topics that are being observed within regulated laboratories. We will also discuss various processes that you need to implement in order to remain compliant with the latest regulatory guidance and minimize your inspection risk.
<h5>Specific topics that will be covered will include:</h5>
<ul>
<li>Custom Analytical Instrument Qualification (AIQ) based on User Requirement Specifications (URS)
</li>
<li>Repair Qualification (RQ)
</li>
<li>Hidden costs of Self-Qualification
</li>
<li>Computer System Validation (CSV)
</li>
</ul>
<blockquote>
Presenter: Garry Wright (European Laboratory Compliance Specialist, Agilent Technologies)
</blockquote>
<blockquote>
Garry Wright is the European Laboratory Compliance Specialist for Agilent Technologies and a member of the Agilent Compliance Council. Garry worked in Regulated Pharmaceutical industry for 20 years prior to joining Agilent.
</blockquote>
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His industrial experience focussed on development and implementation of Quality Management Systems, GMP training and Compliance Auditing. Garry’s role within Agilent is to provide Compliance Consulting services to Agilent and our customer network.
</blockquote>
<blockquote>
Garry has presented topics relating to Regulatory Compliance, Data Integrity and Instrument Qualification at a variety of Compliance forums over the last 7 years since joining Agilent.
</blockquote>

Agilent Technologies: How to Minimize Compliance Risk in Regulated Laboratories

How to Minimize Compliance Risk in Regulated Laboratories

During this webinar we will take a look at some of the latest trends and hot topics that are being observed within regulated laboratories.

Conventional chemical analysis requires sophisticated sampling and laboratory instrumentation, which are usually costly and time consuming. There is a trend for chemical analyses to shift from complex laboratory procedures to rapid, simple and non-destructive spectroscopic methods that can be used in the field. Handheld Fourier Transform Infrared (FTIR) spectroscopy has the advantage of providing chemical information for rapid in situ site characterization.
Agilent’s portable handheld FTIR spectrometers provide a perfect solution for in-field analysis with great convenience, stability and high-throughput solution to the RMID applications. This online seminar provides a comprehensive introduction to the FTIR in-field testing technology and Agilent TopScan 4300 Handheld spectrometer.
<blockquote>
Presenter: Yanqia Wang, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Dr. Yanqia Wang started working for Agilent Technologies Inc. as a FTIR application Engineer in 2013, providing pre-&amp;post-sale application support. The products he covers from Bench-top FTIR microscopes to various Mobile FTIR spectrometers. Dr. Wang received his PhD of analytical chemistry from Duke University in 2004, doing dynamic IR spectroscopy research. Then he joined Fitzpatrick Center for Photonics at Duke University, doing Tissue Raman spectrometer instrumentation. Since 2007, Dr. Wang worked for Avery Dennison Corp. as a spectroscopist, providing molecular analytical support to the research &amp; development.
</blockquote>

Agilent Technologies: Handheld FTIR for in-field Chemical Analysis

Handheld FTIR for in-field Chemical Analysis

This online seminar provides a comprehensive introduction to the FTIR in-field testing technology and Agilent TopScan 4300 Handheld spectrometer.

In today’s market, obtaining low interest rates has become increasingly challenging. But what if there is still a way to obtain the equipment you need easily and affordably?
Find out in this webinar how our Financial Solutions Team could help your business and take advantage of this limited-time, competitive rate offer on all our manufactured products and services. Count on us to provide personalized and flexible financial solutions to help you overcome budgetary constraints, meet your business goals, and drive innovation. Our Financial Solutions Team will partner with you to understand your unique requirements and develop cost-effective financial solutions that will help you maximize your resources and obtain the latest technology when you need it. 
Join this webinar and discover innovative equipment financing solutions that support your business goals and budget. 
<h5>Learning points:</h5>
<ul>
<li>Learn how financial and leasing services can help to finance your new lab equipment </li>
<li>Learn about innovative equipment financing solutions that support your business goals and budget </li>
<li>Learn how our financial solutions can help you obtain the equipment you need easily and affordably</li>
</ul>
 
<h5>Who should attend:</h5>
<ul>
<li>Laboratory leaders and managers who require lab equipment to keep the lab operation and competitive</li>
<li>Laboratory owners who want and need to invest in lab infrastructure </li>
<li>Everyone who is interested in competitive financial solutions for their analytical laboratory</li>
</ul>
 
<blockquote>
Presenter: Roel Philippart (Program Development Manager, Financial Solutions EMEA, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Roel started in 2021 as Program Delelopment Manager at Thermo Fisher Financial Solutions, specifically for the EMEA region.
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Thermo Fisher Scientific: Accelerate discovery, enable success with personalized and flexible financial solutions and market competitive rates

Accelerate discovery, enable success with personalized and flexible financial solutions and market competitive rates

Join this webinar and discover innovative equipment financing solutions that support your business goals and budget. 

Accelerate discovery with flexible financial solutions

The analysis of mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH) in food samples is a challenging application. Don´t miss this opportunity to ask our experts all your questions regarding the fully automated LC/GC workflow for MOAH/MOAH analysis.
We start with a brief introduction where we talk about upcoming changes in the legal requirements for MOSH/MOAH analysis. The remaining time is fully dedicated to your questions.
There are three ways to submit your questions:
<ul>
<li>Fill out the box on the webinar registration form</li>
<li>For more detailed questions, you can email us at: analyze.eu@thermofisher.com</li>
<li>Ask your questions on the day using the chat function during the live session</li>
</ul>
Of course you are welcome to join even if you don´t have a specific question, so you can pick up useful information and build up expertise.
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Presenter: Jeroen Weyts (SampleQ Analytical Support GC-MS, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Presenter: Jorn Hofsteenge (SampleQ Analytical Support GC)
</blockquote>
<blockquote>
Presenter: Inge de Dobbeleer (Sample Q Account Manager)
</blockquote>
<blockquote>
Presenter: Petra Gerhards (Regional Marketing Manager for GC &amp; GC-MS, EMEA, Thermo Fisher Scientific)
</blockquote>

Thermo Fisher Scientific: Ask-the-experts session on MOSH/MOAH analysis

Ask-the-experts session on MOSH/MOAH analysis

Don´t miss this opportunity to ask our experts all your questions regarding the fully automated LC/GC workflow for MOAH/MOAH analysis.

When developing GC methods, numerous variables require careful consideration and it can often be difficult to establish which adjustments and optimisations will provide the desired separation.
This webinar examines the critical method parameters that should be optimised to maximize separation selectivity and achieve resolution of target analytes. The webinar begins with considering analyte physico-chemical properties and establishing the overall method development goals, before examining the GC system configuration, including inlet type and liners and selection of a suitable carrier gas. We then move on to discuss selection of capillary column dimensions and the importance of stationary phase for optimising separation selectivity. These considerations are then bought together in as defined strategies for sequential method optimisation of both existing and new GC applications.
The webinar concludes with a discussion of the benefits provided fast GC and examines how existing methods can be translated to fast GC to provide compelling reductions in analysis time and improved lab efficiency.
<h5>Learning objectives:</h5>
<ul>
<li>Understand where to start when developing a standard GC method.</li>
<li>Learn how to maximize selectivity of chromatography in GC method development.</li>
<li>Discover how to transition standard GC methods to Fast GC.</li>
</ul>
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Presenter: Kirsty Ford
</blockquote>
<blockquote>
Kirsty Ford is a Senior Chromatography Technical Specialist at Avantor. As part of the technical team they support colleagues, distributors, and customers, worldwide, on a range of chromatographic products including GC and HPLC columns. With experience as a remote support engineer with Agilent Technologies, focusing on GC and GCMS, they bring a wealth of knowledge in chromatography, troubleshooting and product insight.
</blockquote>

Optimising GC method development

This webinar examines the critical GC method parameters that should be optimised to maximize separation selectivity and achieve resolution of target analytes.

How do you know if your peak is “pure”? How do you know if your sample conforms to your gold standard? OpenLab CDS provides the tools to answer these questions. This seminar will show you how.
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Presenter: Richard Mutkoski (Laboratory Informatics Application Engineer, Agilent Technologies, Inc.)
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<blockquote>
Richard Mutkoski has been a field representative for over 27 years for both hardware and software. In his current role as an Informatics Application Engineer, Rich presents technical solutions of the OpenLab suite of products to customers worldwide. Prior to his tenure at Agilent Rich spent 15 years in a variety of Pharma QA/QC and R&amp;D positions providing him a unique understanding of those workflows, bottlenecks and challenges.
</blockquote>

Agilent Technologies: Save Time Using the New Integration Optimizer in OpenLab CDS

Save Time Using the New Integration Optimizer in OpenLab CDS

How do you know if your peak is “pure”? How do you know if your sample conforms to your gold standard?