<h3><strong>Program CEEPC/IPM/CMSC 2022</strong></h3>
<blockquote>
<p><a href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/abstractbook_2022_3bec805e4e/abstractbook_2022.pdf"><strong>Complete program including abstracts for download</strong></a></p>
</blockquote>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Konference_CEEPC_IPM_CMSC_2022_2_aa28bf7c17/CSHS-Konference-CEEPC-IPM-CMSC-2022-2.webp" alt="CSMS: Conference CEEPC/IPM/CMSC 2022"/></p>
<h3><strong>Saturday October 1, 2022</strong></h3>
<h4><strong>8:50 - 10:50 Session V – Applications in Biomedicine 2</strong></h4>
<ul>
<li>Chairperson: Haci Mehmet Kayili</li>
</ul>
<h5><strong>8:50-9:10 Proteomic Analysis of Hepatitis B Virus</strong></h5>
<ul>
<li>Martin Hubálek</li>
</ul>
<p>According to the World Health Organisation, an estimated 296 million people worldwide are infected with Hepatitis B virus (HBV). HBV is a small enveloped DNA virus from Hepadnaviridae family that persists in the infected hepatocytes by establishing an episomal covalently closed circular double-stranded DNA (cccDNA) genome containing four open reading frames (C, P, S and X). The ORFs largely overlap and encode multiple proteins using different in-frame start codons. The S ORF encodes three forms of surface envelope glycoproteins S-, M-, and L- HBs). The HBV preC-C gene gives rise to two different products translated from distinct mRNAs – core protein (HBc) and precore protein (HBe). Despite their high sequence similarity, these proteins exhibit different functions and subcellular localizations. The P ORF encodes viral polymerase, and the X ORF encodes regulatory HBx protein.</p>
<p>Mass Spectrometry department of IOCB has established a collaboration with the groups of Iva Pichova and Jan Weber from IOCB. This collaboration on proteomics experiments lead to the discovery of several important biological and biochemical findings including identification of interacting partners of HBc, HBx and HBe proteins or posttranslational modifications of HBc protein. The collaboration resulted in several publications. The proteomic analysis of individually expressed viral proteins has also captured out-of-frame products suggesting the possibility of frameshift or alternative internal initiation of translation. The presentation will highlight the proteomic analyses of HBV at IOCB</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Konference_CEEPC_IPM_CMSC_2022_Proteomic_Analysis_of_Hepatitis_B_Virus_Martin_Hubalek_a95dd6216f/CSHS-Konference-CEEPC-IPM-CMSC-2022-Proteomic-Analysis-of-Hepatitis-B-Virus-(Martin-Hubalek).webp" alt="CSMS: Conference CEEPC/IPM/CMSC 2022: Proteomic Analysis of Hepatitis B Virus (Martin Hubálek)"/></p>
<h5><strong>9:10-9:30 The single amino acid substitutions in Mason-Pfizer Monkey Virus matrix protein modulate its proteolytic cleavage rate</strong></h5>
<ul>
<li>Jakub Sýs</li>
</ul>
<p>N-terminal domain of polyprotein Gag of Mason-Pfizer Monkey Virus (M-PMV) Matrix protein (MA) is naturally myristoylated on its N-terminus. When MA is a part of polyprotein Gag, the myristate moiety is buried inside hydrophobic pocket and exposed probably upon interaction with host cell plasma membrane (PM). This mechanism called myristoyl switch does not occur in M-PMV as readily as it does in HIV-1, suggesting that it may have an important role in M-PMV maturation by regulating the MA cleavage from Gag polyprotein.</p>
<p>To address this hypothesis, we have treated the myristoylated (myrMAPPHis) and nonmyristoylated MAPPHis (nonmyrMAPPHis) M PMV construct, bearing the cleavage site for M-PMV viral protease (Pr13), on artificial liposomes mimicking PM by Pr13 for several time points. In contrast to rapidly degraded nonmyrMAPPHis even without liposomes, the myrMAPPHis, surprisingly, become cleaved more frequently only after addition of liposomes indicating the possible exposure of myristate upon interaction with PM.</p>
<p>To support our findings, we have designed and examined also four mutants of MAPPHis M PMV with single amino acid substitutions with expectation to block or, conversely, facilitate the myristoyl switch by stabilization (A79V, A79L) or destabilization (I51A, I86A) of MA M PMV hydrophobic pocket. The mutants A79V and A79L were cleaved even less effectively than myrMAPPHis as well as the degradation of mutants I51A and I86A was faster compared to nonmyrMAPPHis. The different cleavage rates of proteins were confirmed also on structural level by using method of hydrogendeuterium exchange coupled with mass spectrometric detection. It shows that the protease cleavage site has different dynamics in proteins as a result of disruption/stabilisation of hydrophobic pocket.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Konference_CEEPC_IPM_CMSC_2022_The_single_amino_acid_substitutions_in_Mason_Pfizer_Monkey_Virus_matrix_protein_modulate_its_proteolytic_cleavage_rate_Jakub_Sys_e300792938/CSHS-Konference-CEEPC-IPM-CMSC-2022-The-single-amino-acid-substitutions-in-Mason-Pfizer-Monkey-Virus-matrix-protein-modulate-its-proteolytic-cleavage-rate-(Jakub-Sys).webp" alt="CSMS: Conference CEEPC/IPM/CMSC 2022: The single amino acid substitutions in Mason-Pfizer Monkey Virus matrix protein modulate its proteolytic cleavage rate (Jakub Sýs)"/></p>
<h5><strong>9:30-9:50 Cardiac alarmins as residual risk markers of atherosclerosis under lipid-lowering therapy</strong></h5>
<ul>
<li>Viorel-Iulian Suica</li>
</ul>
<p>Background: The major cause in the initiation and progression of atherosclerosis are the high levels of low-density lipoproteins. Although statin treatment can effectively lower these levels, there is still a residual risk of cardiovascular events. We hypothesize that a specific panel of alarmins, a family of stress-sensing molecules, could indicate the persistence of silent atherosclerosis residual risk. </p>
<p>Methods: New Zeeland White rabbits were divided into: the control group (C) with standard diet, a group which received a high-fat diet for 12 weeks (Au) and a treated hyperlipidemic group, with a lipid diet for 8 weeks followed by standard diet and hypolipidemic treatment (atorvastatin and PCSK9 siRNA-inhibitor) for 4 weeks (Asi). We used the LTQ Orbitrap Velos Pro mass spectrometer to analyse the left ventricle lysates. The experiments were complemented by immunologic and genomic assays to corroborate the data.</p>
<p>Results: The hyperlipidemic diet determined a general alarmin up-regulation tendency over C group. A significant spectral abundance increase was measured for specific heat shock proteins, S100 family members, HMGB1 and Annexin A1. The hypolipidemic treatment demonstrated a reversed regulation trend, with non-significant spectral alteration over the C group for some identified alarmins.</p>
<p>Conclusion: Our study highlights the discriminating potential of alarmins in hyperlipidemia or following a hypolipidemic treatment.</p>
<h5><strong>9:50-10:10 Cervical mucus – a non-invasive uterine biomarker source?</strong></h5>
<ul>
<li>Tomáš Oždian</li>
</ul>
<p>Cervical mucus (CM) is a viscous fluid produced by cervical glands located in the myometrium of the uterine cervix. Usually, CM forms a plug between vagina and uterus. During the ovulation, CM starts to be more fluidic to allow the sperm to go through. During the ovulation, there is a good window for non-invasive sampling of the CM, originating from uterine derived tissues. The main hypothesis for CM proteomic study is to develop a method for CM sampling, processing and to answer if there are enough proteins in the CM for potential biomarker search. The resulting protocol consists of mucus dissolution, multi-enzyme digestion, and LC-MS proteomic analysis. The optimized approach allows to identify more than thousand proteins from every sample tested. The bioinformatic analysis reveals that the identified proteins are both intra and extra cellular and discovers the proteins with enriched expression in the broader female reproductive tract. To our best knowledge, we provide the most extensive proteomic characterization available.</p>
<h5><strong>10:10-10:30 High-Throughput µLC-MS/MS Lipidomics of 3D In Vitro Disease Models to Investigate Lipid Dysregulation</strong></h5>
<ul>
<li>Darshak Gadara</li>
</ul>
<p>Microflow liquid chromatography interfaced with mass spectrometry is increasingly applied for the high-throughput profiling of biological samples, as it demonstrated an acceptable tradeoff between sensitivity and reproducibility. However, a limited number of applications developed in lipidomics. This study introduces a robust, sensitive, and high-throughput μLC-MS/MS lipidomics workflow, applied in a differential lipidome study of APOE 3 and 4 phenotypes in iPSC-derived cerebral organoids (CO). First, we optimized the microbore column gradient conditions, injecting a mixture of 15 lipid standards on the UHPLC system coupled to a 6469 QQQ. Our μLC-MS/MS method allows quantitation of 351 lipid species from the single CO. The microflow lipidomics shows an average 3.7-fold increase in response compared to a conventional high-flow method. To benchmark the quantitative performance, 303 samples were acquired over 75 hours. The median coefficient of variation (CV) of 351 lipid species was 12.95%, only 26 lipid species show CV higher than 30%. We demonstrated that microflow separation coupled to three-stage quadruple MS substantially increases the sensitivity and allows for robust multiplexed lipid profiling (including cholesterol determination) in a single cerebral organoid. As a proof of concept, lipidomics analysis was performed for the lipid extract of APOE 3/3 and APOE 4/4 (n=10) CO samples. To our knowledge, this is the first systematic report to demonstrate the microflow LC-MS/MS allows for sensitive, high-throughput, and robust measurement of global lipidome, opening an avenue for routine application of microflow separation in the field of lipidomics.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Konference_CEEPC_IPM_CMSC_2022_High_Throughput_LC_MS_MS_Lipidomics_of_3_D_In_Vitro_Disease_Models_to_Investigate_Lipid_Dysregulation_Darshak_Gadara_0935fe540d/CSHS-Konference-CEEPC-IPM-CMSC-2022-High-Throughput-LC-MS-MS-Lipidomics-of-3D-In-Vitro-Disease-Models-to-Investigate-Lipid-Dysregulation-(Darshak-Gadara).webp" alt="CSMS: Conference CEEPC/IPM/CMSC 2022: High-Throughput µLC-MS-MS Lipidomics of 3D In Vitro Disease Models to Investigate Lipid Dysregulation (Darshak Gadara)"/></p>
<h5><strong>10:30-10:50 Multi-omics network analysis in atherosclerosis reveals mechanisms driving the progression towords complicated lesion</strong></h5>
<ul>
<li>Eva Csosz</li>
</ul>
<p>From a biological point of view, it is crucial to understand the mechanisms laying behind atherosclerosis and its complicated forms. In the process of atherosclerosis, first, an atheromatous plaque builds up, which in some conditions can lead to the appearance of complicated lesions. The complicated lesion is characterized by ruptures on the atherosclerotic plaque surface and/or hemorrhage into the plaque. According to the WHO, hemorrhaged lesions, contribute to a considerable extent of deaths worldwide.</p>
<p>The main goal of our project was to perform a multi-omics study involving transcriptomics and proteomics data to get more insights into the pathophysiological processes dominating the complicated lesions.</p>
<p>Transcriptomic (RNAseq) and proteomic (label-free quantification) data were obtained by the analysis of artery samples originating from healthy arteries, atheromatous lesions, and complicated lesions. Both data types were examined separately by Ingenuity Pathway Analysis and later an overlay of the networks was achieved.</p>
<p>120 differentially expressed (DE) proteins and more than 4000 DE genes were detected. The deep analysis of the data could identify the proteins and transcripts characteristic of the complicated lesions and could reveal the pathways specific to atheroma and complicated lesions, respectively. The DE genes were arranged into 25 networks, while the DE proteins were into 12 networks. The lower number of DE proteins compared to the number of DE genes did not result in loss of information, indicating the power of the proteomics experiments. In spite of providing a lower number of DE items, the biological information achievable from proteomics experiments has equal value compared to transcriptomics data.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Konference_CEEPC_IPM_CMSC_2022_Multi_omics_network_analysis_in_atherosclerosis_reveals_mechanisms_driving_the_progression_towords_complicated_lesion_Eva_Csosz_aa54a2b04f/CSHS-Konference-CEEPC-IPM-CMSC-2022-Multi-omics-network-analysis-in-atherosclerosis-reveals-mechanisms-driving-the-progression-towords-complicated-lesion-(Eva-Csosz).webp" alt="CSMS: Conference CEEPC/IPM/CMSC 2022: Multi-omics network analysis in atherosclerosis reveals mechanisms driving the progression towords complicated lesion (Eva Csosz)"/></p>
<h5><strong>10:50 - 11:10 Coffee break</strong></h5>
<h4><strong>11:10 - 12:00 Plenary lecture III:: Light-mediated discovery of surfaceome nanoscale organization and inter-cellular receptor interaction networks</strong> (Chairperson: Pavel Bouchal)</h4>
<ul>
<li>Bernd Wollscheid</li>
</ul>
<p>The molecular nanoscale organization of the surfaceome is a fundamental regulator of cellular signaling in health and disease. Technologies for mapping the spatial relationships of cell surface receptors and their extracellular signaling synapses would unlock theranostic opportunities to target protein communities and the possibility to engineer extracellular signaling. Here, we develop an optoproteomic technology termed LUX-MS that enables the targeted elucidation of acute protein interactions on and in between living cells using light-controlled singlet oxygen generators (SOG). By using SOG-coupled antibodies, small molecule drugs, biologics and intact viral particles, we demonstrate the ability of LUX-MS to decode ligand receptor interactions across organisms and to discover surfaceome receptor nanoscale organization with direct implications for drug action. Furthermore, by coupling SOG to antigens we achieved light-controlled molecular mapping of intercellular signaling within functional immune synapses between antigen-presenting cells and CD8⁺ T cells providing insights into T cell activation with spatiotemporal specificity. LUX-MS based decoding of surfaceome signaling architectures thereby provides a molecular framework for the rational development of theranostic strategies.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Konference_CEEPC_IPM_CMSC_2022_Light_mediated_discovery_of_surfaceome_nanoscale_organization_and_inter_cellular_receptor_interaction_networks_Bernd_Wollscheid_019214ab5c/CSHS-Konference-CEEPC-IPM-CMSC-2022-Light-mediated-discovery-of-surfaceome-nanoscale-organization-and-inter-cellular-receptor-interaction-networks-(Bernd-Wollscheid).webp" alt="CSMS: Conference CEEPC/IPM/CMSC 2022: Light-mediated discovery of surfaceome nanoscale organization and inter-cellular receptor interaction networks (Bernd Wollscheid)"/></p>
<h4><strong>12:00 - 12:20 Poster prize, Closing remarks</strong></h4>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Predavani_oceneni_konference_CEEPC_IPM_CMSC_2022_Ales_Kvasnicka_a_Michael_Volny_4c0967dd3b/CSHS-Predavani-oceneni-konference-CEEPC-IPM-CMSC-2022-(Ales-Kvasnicka-a-Michael-Volny).webp" alt="ČSHS: Conference prize CEEPC/IPM/CMSC 2022 (Aleš Kvasnička a Michael Volný)"/></p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Eu_PA_cestovni_granty_Nejlepsi_kratke_sdeleni_Kalaninova_Zuzana_a_Eva_Csosz_ef6a262eae/CSHS-EuPA-cestovni-granty-Nejlepsi-kratke-sdeleni-(Kalaninova-Zuzana-a-Eva-Csosz).webp" alt="ČSHS: EuPA travel grants: Short talk prize CEEPC/IPM/CMSC 2022 (Kalaninová Zuzana a Eva Csosz)"/></p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Vyhlaseni_nejlepsiho_posteru_Konference_CEEPC_IPM_CMSC_2022_Anton_Skriba_a_Michael_Volny_0010fccaaa/CSHS-Vyhlaseni-nejlepsiho-posteru-Konference-CEEPC-IPM-CMSC-2022-(Anton-Skriba-a-Michael-Volny).webp" alt="ČSHS: Poster prize CEEPC/IPM/CMSC 2022 (Anton Škríba a Michael Volný)"/></p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Eu_PA_cestovni_granty_Nejlepsi_poster_Jadeja_Siddharth_a_Eva_Csosz_dac2e7c761/CSHS-EuPA-cestovni-granty-Nejlepsi-poster-(Jadeja-Siddharth-a-Eva-Csosz).webp" alt="ČSHS: EuPA travel grants: Poster prize CEEPC/IPM/CMSC 2022 (Jadeja Siddharth a Eva Csosz)"/></p>
<h5><strong>12:20 - 13:30 Lunch</strong></h5>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CSHS_Konference_CEEPC_IPM_CMSC_2022_Obcerstveni_44ad451fcc/CSHS-Konference-CEEPC-IPM-CMSC-2022-Obcerstveni.webp" alt="CSMS: Conference CEEPC/IPM/CMSC 2022: Coffe break"/></p>


Conference CEEPC/IPM/CMSC 2022 (Day 3)

<p><strong>STARSS project is approaching its end after more than five years. A few more months remain before it will be concluded. The major objective of the project was to create a strong team of researchers enabling significant progress in the field of the separation science. The annual STARSS conferences have always been a good opportunity to bring people from several Czech and European institutions in Hradec Kralove where we have met face to face for a few days in order to inform each other about the progress in the research. It is clear that the focus of these conferences has been on the exchange in scientific information. However, an integral part of our previous conferences has also included informal meetings when we had time to talk about issues sometimes even completely outside of science perhaps with a drink and food. Social part of conferences is simply indispensable.</strong></p>
<p><strong>I trust that this conference will be at least as interesting as all the previous ones. Its program is rich and includes presentations by renowned “icons” of separation science from both abroad and the Czech Republic, as well as talks given by students and postdocs. Such “cross-pollination” will certainly be uplifting for all involved. I wish all those who attend this conference a pleasant stay in Hradec Králové and enjoyable conferencing.</strong></p>
<p><strong><a href="https://lcms.cz/articles?search=Franti%C5%A1ek+%C5%A0vec">Prof. František Švec</a></strong></p>
<h3><strong>Program: 6th STARSS Conference on Separation Science</strong></h3>
<ul>
<li><a href="https://portal.faf.cuni.cz/getattachment/Projects/STARSS/Events/6th-STARSS-conference/Program/2022-STARSS-booklet.pdf.aspx?lang=en-GB"><strong>Conference booklet including speakers bio</strong></a></li>
</ul>
<h3><strong>DAY 1: Monday 17. 10. 2022</strong></h3>
<h5><strong>08:00 – 09:00 REGISTRATION</strong></h5>
<h5><strong>09:00 – 09:20 Welcoming address</strong></h5>
<ul>
<li>Prof. Petr Solich, Prof. František Švec, Prof. Lucie Nováková</li>
<li>Assoc. Prof. Jaroslav Roh (the dean of the Faculty of Pharmacy, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h4><strong>SESSION I: IMPORTANCE OF SEPARATION SCIENCE FOR CLINICAL APPLICATIONS</strong></h4>
<ul>
<li>Chairperson: Prof. František Švec</li>
</ul>
<h5><strong>09:20 – 10:00 L-01: UHPSFC/MS as a powerful tool for high-throughput lipidomic quantitation in cancer screening</strong></h5>
<ul>
<li><a href="https://lcms.cz/articles?search=Michal+Hol%C4%8Dapek">Prof. Michal Holčapek</a> (University of Pardubice, Czech Republic)</li>
</ul>
<h5><strong>10:00 – 10:40 L-02: Selected ion flow tube mass spectrometry, SIFT-MS, analyses of volatile metabolites in exhaled breath</strong></h5>
<ul>
<li>Prof. Patrik Španěl (J. Heyrovský Institute of Physical Chemistry, Prague, Czech Republic)</li>
</ul>
<h5><strong>10:40 – 11:10 Coffee-break and discussion</strong></h5>
<h4><strong>SESSION II: BIOPHARMACEUTICALS</strong></h4>
<ul>
<li>Chairperson: Prof. Lucie Nováková</li>
</ul>
<h5><strong>11:10 – 11:50 L-03: Simplifying the characterization of complex biopharmaceutical products through the use of ultra-short columns or multi-isocratic elution mode</strong></h5>
<ul>
<li>Dr. Davy Guillarme (University of Geneva, Switzerland)</li>
</ul>
<h5><strong>11:50 – 12:20 L-04: Analysis of therapeutic proteins by multidimensional LC: How far can we go?</strong></h5>
<ul>
<li>Dr. Valentina D ́Atri (University of Geneva, Switzerland)</li>
</ul>
<h5><strong>12:20 – 12:40 L-05: pyroLC: online thermal decomposition of proteins as a tool for ultra-fast bottom-up proteomics</strong></h5>
<ul>
<li>Dr. Juraj Lenčo (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>12:40 – 13:00 L-06: RPLC-UV and HILIC-UV characterization of home-made ramucirumab-based antibody-drug conjugate</strong></h5>
<ul>
<li>Denis Naplekov (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>13:00 – 14:00 Lunch</strong></h5>
<h4><strong>SESSION III: 2D SEPARATIONS</strong></h4>
<ul>
<li>Chairperson: Assoc. Prof. Jiří Urban</li>
</ul>
<h5><strong>14:00 – 14:40 L-07: What can we expect from LC x LC compared to conventional 1D-LC</strong></h5>
<ul>
<li>Prof. Sabine Heinisch (Université Claude Bernard Lyon 1, Lyon, France)</li>
</ul>
<h5><strong>14:40 – 15:20 L-08: Modelling of analyte profiles and band broadening generated by interface loops used in multi-dimensional liquid chromatography</strong></h5>
<ul>
<li>Prof. Ken Broeckhoven (Vrije Universiteit Brussel, Belgium)</li>
</ul>
<h5><strong>15:20 – 15:50 L-09: Off-line LC x SFC in the prospect of upgrading natural or recycled products</strong></h5>
<ul>
<li>Dr. Karine Faure (Université Claude Bernard Lyon 1, Lyon, France)</li>
</ul>
<h5><strong>15:50 – 16:20 L-10: Two-dimensional liquid chromatographic separations of complex samples of industrial products and intermediates</strong></h5>
<ul>
<li><a href="https://lcms.cz/articles?search=Petr+%C4%8Cesla"><strong>Assoc. Prof. Petr Česla</strong></a> (University of Pardubice, Czech Republic)</li>
</ul>
<h5><strong>16:20 – 16:50 Coffee-break and discussion</strong></h5>
<h4><strong>SESSION IV: IMPORTANCE OF STEROIDS</strong></h4>
<ul>
<li>Chairperson: Prof. Marcela Segundo</li>
</ul>
<h5><strong>16:50 – 17:30 L-11: An image of the future of steroid biochemistry</strong></h5>
<ul>
<li>Prof. Ruth Andrew (University of Edinburgh, UK)</li>
</ul>
<h5><strong>17:30 – 18:00 L-12: Ecdysterone metabolism: A holistic view on compound identification for doping control</strong></h5>
<ul>
<li>Prof. Maria Kristina Parr (Freie Universität Berlin, Berlin, Germany)</li>
</ul>
<h5><strong>18:00 – 18:30 L-13: New liquid chromatography-tandem mass spectrometry method for targeted profiling of steroids in mouse plasma</strong></h5>
<ul>
<li>Taťána Gazárková (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>18:30 – 19:30 Welcome drink</strong></h5>
<h3><strong>DAY 2: Tuesday 18. 10. 2022</strong></h3>
<h5><strong>08:00 – 09:00 REGISTRATION</strong></h5>
<h4><strong>SESSION V: SUPERCRITICAL FLUID CHROMATOGRAPHY AND EXTRACTIONS</strong></h4>
<ul>
<li>Chairperson: Assoc. Prof. Radim Kučera</li>
</ul>
<h5><strong>09:00 – 09:30 L-14: Supercritical fluid extraction and chromatography in life science applications</strong></h5>
<ul>
<li>Prof. Charlotta Turner (Lund University, Lund, Sweden)</li>
</ul>
<h5><strong>09:30 – 10:00 L-15: Supercritical fluid chromatography – tandem mass spectrometry for analysis of vitamin D metabolites in biological samples</strong></h5>
<ul>
<li>Dr. Margareta Sandahl (Lund University, Lund, Sweden)</li>
</ul>
<h5><strong>10:00 – 10:30 L-16: The effect of make-up solvent composition on responses in SFC-MS: Electrospray vs UniSpray</strong></h5>
<ul>
<li>Dr. Kateřina Plachká (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>10:30 – 11:00 L-17: UHPSFC-MS/MS versus 2D-UHPLC-MS/MS in chiral separation of Propranolol and its Hydroxy Metabolites</strong></h5>
<ul>
<li>Lukas Harps (Freie Universität Berlin, Berlin, Germany)</li>
</ul>
<h5><strong>11:00 – 11:30 Coffee-break and discussion</strong></h5>
<h4><strong>SESSION VI: COLUMN TECHNOLOGY</strong></h4>
<ul>
<li>Chairperson: Prof. Dalibor Šatínský</li>
</ul>
<h5><strong>11:30 – 12:10 L-18: Hypercrosslinked monolithic stationary phases in proteomics</strong></h5>
<ul>
<li>Assoc. Prof. Jiří Urban (Masaryk University, Brno, Czech Republic)</li>
</ul>
<h5><strong>12:10 – 12:40 L-19: Guidelines for tuning the macropore structure of monolithic columns for high-performance liquid chromatography</strong></h5>
<ul>
<li>Dr. Sebastiaan Eeltink (Vrije Universiteit Brussel, Belgium)</li>
</ul>
<h5><strong>12:40 – 13:10 L-20: Strategies and chemistry in column development</strong></h5>
<ul>
<li>Assoc. Prof. Michal Kohout (University of Chemistry and Technology, Prague, Czech Republic)</li>
</ul>
<h5><strong>13:10 – 14:30 Lunch</strong></h5>
<h4><strong>SESSION VII: RETENTION MECHANISMS AND STATIONARY PHASES</strong></h4>
<ul>
<li>Chairperson: Prof. Spas Kolev</li>
</ul>
<h5><strong>14:30 – 15:00 L-21: Understanding the mechanism, advantages and limitations of hydrophilic interaction liquid chromatography</strong></h5>
<ul>
<li>Prof. David McCalley (University of West England, UK)</li>
</ul>
<h5><strong>15:00 – 15:30 L-22: Study of molecular structures through retention mechanisms in liquid chromatography: New trends and applications</strong></h5>
<ul>
<li>Dr. Jean-Christophe Garrigues (Paul Sabatier University - Toulouse III, Toulouse, France)</li>
</ul>
<h5><strong>15:30 – 16:00 L-23: Problems of stationary phases in SFC</strong></h5>
<ul>
<li>Prof. Lucie Nováková (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>16:00 – 16:30 L-24: The chromatographic behaviour of pharmaceuticals on stationary phases based on metal oxides</strong></h5>
<ul>
<li>Assoc. Prof. Radim Kučera (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>16:30 – 17:00 Coffee-break and discussion</strong></h5>
<h4><strong>SESSION VIII: SAMPLE PREPARATION AND APPLICATIONS</strong></h4>
<ul>
<li>Chairperson: Assoc. Prof. Hana Sklenářová</li>
</ul>
<h5><strong>17:00 – 17:30 L-25: Glucosinolate profiling in Brassicaceae family: instrumental analysis and biological application</strong></h5>
<ul>
<li>Dr. Iva Pavlovic (Palacký University, Olomouc, Czech Republic)</li>
</ul>
<h5><strong>17:30 – 18:00 L-26: Flow programming for the development of online solid-phase extraction</strong></h5>
<ul>
<li>Assoc. Prof. Petr Chocholouš (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>18:00 – 18:30 L-27: Automated tandem homogeneous liquid-liquid extraction and centrifugation-less deproteination for complex sample analysis on HPLC</strong></h5>
<ul>
<li>Dr. Burkhard Horstkotte (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>19:00 – 22:00 Conference dinner</strong></h5>
<h3><strong>DAY 3: Wednesday 19. 10. 2022</strong></h3>
<h4><strong>WORKSHOPS: FACULTY OF PHARMACY</strong></h4>
<h5><strong>08:00 – 10:30 W1: Supercritical fluid extraction of polar and nonpolar compounds from Eucalyptus sp.</strong></h5>
<ul>
<li>Laboratory 916, 8th floor, Faculty of Pharmacy</li>
<li>Dr. Veronika Pilařová (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>08:00 – 10:30 W2: MetAmino® Kit – simple and easy sample preparation method for your LC-MC or GC-MS analysis</strong></h5>
<ul>
<li>Student’s Laboratory, 3rd floor, Faculty of Pharmacy</li>
<li>Ing. Jana Volková (Chromservis, Czech Republic)</li>
</ul>
<h5><strong>10:30 – 11:00 Coffee-break and discussion</strong></h5>
<h5><strong>11:00 – 13:30 W3: Who will help you with sample prep and liquid handling?</strong></h5>
<ul>
<li>Student’s Laboratory, 4th floor, Faculty of Pharmacy</li>
<li>Dr. Martina Riesová (<a href="https://lcms.cz/companies/50"><strong>Waters</strong></a>, Prague, Czech Republic)</li>
</ul>
<h5><strong>13:30 – 14:30 Lunch</strong></h5>
<h5><strong>14:30 – 17:00 W4: Practical application of nanofibers for advanced extraction approaches in chromatography</strong></h5>
<ul>
<li>Student’s Laboratory no. 524, 4th floor, Faculty of Pharmacy</li>
<li>Prof. Dalibor Šatínský, Dr. Ivona Lhotská (Charles University, Hradec Králové, Czech Republic)</li>
</ul>
<h5><strong>17:00 – 18:00 Coffee-break and discussion</strong></h5>


6th STARSS Conference on Separation Science (Program)

<p><strong>In the  week from October 17 &amp; 24 , 2022, the following webinars await you in the field of gas / solid phase and especially GC and GC/MS.</strong></p>
<blockquote>
<h4><a href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong>.</p>
</blockquote>
<h5><strong>1. Agilent Technologies: A Discussion on the Theory of IR Spectroscopy</strong></h5>
<ul>
<li>Mo, 17.10.2022, 21:30 (CEST)</li>
</ul>
<p>This session will focus on the theory of Infrared and will discuss some modern infrared analytical techniques.</p>
<h5><strong>2. Phenomenex: Advances in GC for Environmental Semivolatile and Volatile Organic Analysis</strong></h5>
<ul>
<li>Tu, 18.10.2022, 19:00 (CEST)</li>
</ul>
<p>New technologies in GC that facilitates Semivolatile and volatile analysis,method development tips and tricks and Understand GC column role.</p>
<h5><strong>3. Waters Corporation: APGC-MS/MS a game changer for routine pesticide analysis: Reaching new heights</strong></h5>
<ul>
<li>Th, 20.10.2022, 11:00 (CEST)</li>
</ul>
<p>The use of GC-MS/MS utilizing APGC has been shown to offer significant improvements in performance over electron ionization (EI) for pesticide residue analysis, in terms of selectivity and specificity.</p>
<h5><strong>4. Agilent Technologies: MicroLab Software introduction for Agilent FTIR systems</strong></h5>
<ul>
<li>Th, 20.10.2022, 20:00 (CEST)</li>
</ul>
<p>This online seminar provides a comprehensive introduction to Agilent FTIR spectrometers and MicroLab software to help customers from Academic F15Teaching Labs to facilitate their operation.</p>
<h5><strong>5. Agilent Technologies: Meet a Versatile Agilent Cary 630 FTIR</strong></h5>
<ul>
<li>Mo, 24.10.2022, 21:30 (CEST)</li>
</ul>
<p>Developing models for FTIR quantitative analysis is simple using Agilent Cary 630 FTIR spectrometers and MicroLab FTIR software.</p>
<h5><strong>6. ACD/Labs: What&#39;s That Peak? Structure Elucidation &amp; Verification Virtual Symposium (Day 1)</strong></h5>
<ul>
<li>Tu, 25.10.2022, 15:30 (CEST)</li>
</ul>
<p>What’s in my sample? Did I make what I think I made? What’s that peak?</p>
<h5><strong>7. Wiley: Automate GC-MS analysis with KnowItAll MS Expert</strong></h5>
<ul>
<li>Tu, 25.10.2022, 16:00 (CEST)</li>
</ul>
<p>Discover how you can save hours of manual GC-MS analysis time.</p>
<h5><strong>8. ACD/Labs: What&#39;s That Peak? Structure Elucidation &amp; Verification Virtual Symposium (Day 2)</strong></h5>
<ul>
<li>We, 26.10.2022, 15:30 (CEST)</li>
</ul>
<p>What’s in my sample? Did I make what I think I made? What’s that peak?</p>
<h5><strong>9. Quantum Analytics/Bruker: Polymer Science A to Z: Getting Answers from FTIR and Raman Analyses</strong></h5>
<ul>
<li>We, 26.10.2022, 20:00 (CEST)</li>
</ul>
<p>Let’s tackle the science of polymer analysis using the power of spectroscopy, including identification, quality control and reverse engineering.</p>


Webinars LabRulezGCMS Week 42-43/2022

<p><strong>The Clarity MS Extension is a tool that is used for processing data that has been acquired from selected Mass Spectrometry detectors. Spectral data, together with chromatograms, add a third dimension to analytical data analysis.</strong></p>
<ul>
<li><p>👌 <strong>Combination of MS signals</strong> with conventional GC/HPLC detectors</p>
</li>
<li><p>🔝 MS detectors can be used <strong>in combination with 1000+ instruments</strong> supported in Clarity</p>
</li>
<li><p>💡 MS manufacturers can develop <strong>a driver for their own detectors</strong> using a Clarity Software Development Kit (SDK)</p>
</li>
</ul>
<p><strong>The MS Extension</strong> expands the capability of <strong>Clarity</strong> and <strong>Clarity Offline Chromatography software</strong> by providing interactive spectral analysis, peak purity analysis, and compound identification that is based on a spectral library search. The extension is prepared to function with <strong>single quadrupole MS detectors</strong> and <strong>TOF MS detectors</strong>.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_software_Mass_Spectrometry_Extension_1_7fb5562dc3/DataApex-Clarity-software-Mass-Spectrometry-Extension-1.webp" alt="DataApex: Clarity software - Mass Spectrometry Extension"/></p>
<p>All <strong>data is saved in a single file</strong>; a chromatogram at any m/z value or even only a spectrum can simply be recalled for review after an analysis. <strong>MS spectra</strong>, acquired using an MS detector, may be interactively selected <strong>from a chromatogram signal</strong> for visual inspection and comparison. The spectra may also be used for <strong>peak purity determinations</strong> and <strong>component identification</strong> through spectral libraries.</p>
<p>It is possible to import MS data in <strong>AIA</strong> (cdf), <strong>mzXML</strong>, <strong>MzML</strong>, and <strong>mzData</strong> formats.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Clarity_software_Mass_Spectrometry_Extension_2_6b036064d3/DataApex-Clarity-software-Mass-Spectrometry-Extension-2.webp" alt="DataApex: Clarity software - Mass Spectrometry Extension"/></p>
<p>Control modules for selected detectors (see list of <a href="https://www.dataapex.com/controls"><strong>control modules</strong></a>) are available in Clarity.</p>
<p><strong>Additional control modules for MS detectors can be developed upon request</strong>, please <a href="https://www.dataapex.com/document/contacts"><strong>contact us</strong></a> for availability.</p>
<blockquote>
<h3><strong>Selected supported GC/MS &amp; LC/MS detectors</strong></h3>
</blockquote>
<blockquote>
<h5><strong>LC-MS Detectors</strong></h5>
<ul>
<li><strong>Advion:</strong> Expression</li>
<li><strong>Gilson:</strong> Verity 1920</li>
<li><strong>Konik:</strong> Q4 LCMS</li>
<li><strong>Microsaic:</strong> 4000 MiD</li>
<li><strong>Microsaic:</strong> 4500 MiD</li>
<li><strong>Young In Chromass:</strong> YL9900</li>
</ul>
</blockquote>
<blockquote>
<h5><strong>GC-MS Detectors</strong></h5>
<ul>
<li><strong>Young In Chromass:</strong> ChroZen GC/MS</li>
<li><strong>Young In Chromass:</strong> YL6900</li>
</ul>
</blockquote>
<blockquote>
<h5><strong>GC-MS TOF Detectors</strong></h5>
<ul>
<li><strong>Markes International:</strong> BenchTOF</li>
</ul>
</blockquote>


Clarity software - Mass Spectrometry Extension

ESAS-CSSC 2022 (Day 3)

<p><strong>In the  week from October 24 , 2022, the following webinars await you in the field of gas / solid phase and especially GC and GC/MS.</strong></p>
<blockquote>
<h4><a href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong>.</p>
</blockquote>
<h5><strong>1. Agilent Technologies: Meet a Versatile Agilent Cary 630 FTIR</strong></h5>
<ul>
<li>Mo, 24.10.2022, 21:30 (CEST)</li>
</ul>
<p>Developing models for FTIR quantitative analysis is simple using Agilent Cary 630 FTIR spectrometers and MicroLab FTIR software.</p>
<h5><strong>2. ACD/Labs: What&#39;s That Peak? Structure Elucidation &amp; Verification Virtual Symposium (Day 1)</strong></h5>
<ul>
<li>Tu, 25.10.2022, 15:30 (CEST)</li>
</ul>
<p>What’s in my sample? Did I make what I think I made? What’s that peak?</p>
<h5><strong>3. Wiley: Automate GC-MS analysis with KnowItAll MS Expert</strong></h5>
<ul>
<li>Tu, 25.10.2022, 16:00 (CEST)</li>
</ul>
<p>Discover how you can save hours of manual GC-MS analysis time.</p>
<h5><strong>4. Thermo Fisher Scientific: Walkaway sample-to-vial sample preparation with the EXTREVA ASE system</strong></h5>
<ul>
<li>We, 26.10.2022, 09:00 (CEST)</li>
</ul>
<p>Discover the Thermo Scientific EXTREVA ASE Accelerated Solvent Extractor which boosts sample prep productivity, and efficiency, and brings a new level of consistency.</p>
<h5><strong>5. ACD/Labs: What&#39;s That Peak? Structure Elucidation &amp; Verification Virtual Symposium (Day 2)</strong></h5>
<ul>
<li>We, 26.10.2022, 15:30 (CEST)</li>
</ul>
<p>What’s in my sample? Did I make what I think I made? What’s that peak?</p>
<h5><strong>6. Quantum Analytics/Bruker: Polymer Science A to Z: Getting Answers from FTIR and Raman Analyses</strong></h5>
<ul>
<li>We, 26.10.2022, 20:00 (CEST)</li>
</ul>
<p>Let’s tackle the science of polymer analysis using the power of spectroscopy, including identification, quality control and reverse engineering. </p>
<h5><strong>7. Petro Industry News/Metrohm: Making your quality control of hydraulic and lube oils more efficient</strong></h5>
<ul>
<li>Th, 27.10.2022, 14:00 (CEST)</li>
</ul>
<p>Combining titration and Vis-Near-Infrared Spectroscopy for higher sample throughput &amp; faster results.</p>


Webinars LabRulezGCMS Week 43/2022

<p><strong>In the  week from October 31 , 2022, the following webinars await you in the field of gas / solid phase and especially GC and GC/MS.</strong></p>
<blockquote>
<h4><a href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong>.</p>
</blockquote>
<h5><strong>1. Waters Corporation: Empower Tips: Ask Me Anything About Creating Efficiency in Your Routine Workflow with Simple Automation Steps</strong></h5>
<ul>
<li>Tu, 1.11.2022, 16:00 (CEST)</li>
</ul>
<p>In this workshop we will define a chromatographic workflow with Empower software to support data integrity goals.</p>
<h5><strong>2. C&amp;EN/Metrohm: Peace-of-Mind with Secure Data Management</strong></h5>
<ul>
<li>Tu, 1.11.2022, 18:00 (CET)</li>
</ul>
<p>During this webinar, Kerri-Ann Blake, Product Manager for Titration, and Daniel Schmidt, IT Systems Engineer, will introduce you to the OMNIS data management platform.</p>
<h5><strong>3. Agilent Technologies: Ask the Experts Panel: Pesticides by GC/MS</strong></h5>
<ul>
<li>Tu, 1.11.2022, 20:00 (CET)</li>
</ul>
<p>Join Agilent application scientists and engineers who will be available to provide guidance and expertise for all your hardware, software, and application related questions.</p>
<h5><strong>4. SelectScience/Restek: How to overcome challenges and improve your semivolatile organic compound analysis</strong></h5>
<ul>
<li>We, 2.11.2022, 17:00 (CET)</li>
</ul>
<p>Whether it is PAH analysis in under 10 minutes or a wide calibration range for routine 8270 analysis, there is an Rxi-SVOCms column to meet all needs.</p>
<h5><strong>5. Thermo Fisher Scientific: N-Nitrosamines – the Evolution of the Concerns</strong></h5>
<ul>
<li>We, 2.11.2022, 18:00 (CET)</li>
</ul>
<p>Ask the question: Is the issue we now faced the same issue as that first identified in the Valsartan incident and are the same approaches valid?</p>
<h5><strong>6. Agilent Technologies: Microplastic Pollution: IR Microspectroscopy is Enhancing Chemical Identification</strong></h5>
<ul>
<li>Th, 3.11.2022, 19:00 (CET)</li>
</ul>
<p>We present the FT-IR microspectroscopic analyses of microplastics collected from water samples and living oceanic organisms as a means of tracing the microplastic contamination back to the originating source.</p>
<h5><strong>7. Agilent Technologies: What’s in a UV-Vis-NIR Baseline</strong></h5>
<ul>
<li>Fr, 4.11.2022, 18:00 (CET)</li>
</ul>
<p>Why are corrected baselines important in making a good uv-vis (nir) measurement? What are the components of a baseline and what do they tell us about the performance of the instrument?</p>


Webinars LabRulezGCMS Week 44/2022

<p><strong>In the  week from November 7, 2022, the following webinars await you in the field of gas / solid phase and especially GC and GC/MS.</strong></p>
<blockquote>
<h4><a href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong>.</p>
</blockquote>
<h5><strong>1. Agilent Technologies: A Review of FTIR 21 CFR Compliance Requirements</strong></h5>
<ul>
<li>Mo, 7.11.2022, 21:30 (CET)</li>
</ul>
<p>This presentation will discuss 21CFR requirements and present how they are addressed by MicroLab software for the Cary 630 FTIR.</p>
<h5><strong>2. Shimadzu Corporation: The complete solution for cannabis testing</strong></h5>
<ul>
<li>Tu, 8.11.2022, 09:00 (CET)</li>
</ul>
<p>For the first time on a global scale, the complete process of preparation, extraction and analysis of cannabis will be covered in an online seminar series.</p>
<h5><strong>3. Metrohm: Quality control of medical cannabis in less than 30 seconds</strong></h5>
<ul>
<li>Tu, 8.11.2022, 16:00 (CET)</li>
</ul>
<p>Join Dr. Dave van Staveren and Andreas Agerer from Metrohm International Headquarters on November 8, 2022, at 4 p.m. CET and learn how to use NIRS to make your routine QC of cannabis faster and more efficient!</p>
<h5><strong>4. Shimadzu Corporation/CEM: Quick and easy sample preparation for cannabis and hemp analysis</strong></h5>
<ul>
<li>We, 9.11.2022, 09:00 (CET)</li>
</ul>
<p>For the first time on a global scale, the complete process of preparation, extraction and analysis of cannabis will be covered in an online seminar series.</p>
<h5><strong>5. Shimadzu Corporation/RETSCH: Sample preparation for cannabis products for Q&amp;A and CBD oil extraction</strong></h5>
<ul>
<li>Th, 10.11.2022, 09:00 (CET)</li>
</ul>
<p>The third day of the seminar week is about the analysis-appropriate preparation of cannabis plants and related products.</p>
<h5><strong>6. C&amp;EN/Agilent Technologies: Analysis of Trace Impurities in Hydrogen by Gas Chromatography</strong></h5>
<ul>
<li>Th, 10.11.2022, 19:00 (CET)</li>
</ul>
<p>In this webinar we will discuss the gas chromatography and how it is used to analyze trace impurities in hydrogen gas.</p>


Webinars LabRulezGCMS Week 45/2022

<p><strong>In the  week from November 14, 2022, the following webinars await you in the field of gas / solid phase and especially GC and GC/MS.</strong></p>
<blockquote>
<h4><a href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong>.</p>
</blockquote>
<h5><strong>1. Agilent Technologies: Handheld FTIR – Best On-site Chemistry Analysis Solution</strong></h5>
<ul>
<li>Mo, 14.11.2022, 21:30 (CET)</li>
</ul>
<p>Agilent’s Handheld FTIR spectrometer is a unique and innovative platform for measuring samples on site to yield fast and reliable chemistry analyses.</p>
<h5><strong>2. Thermo Fisher Scientific: &quot;Eat your vegetables,&quot; but how safe are they? Total solutions for comprehensive pesticide residue analysis</strong></h5>
<ul>
<li>Tu, 15.11.2022, 17:00 (CET)</li>
</ul>
<p>Triple quadrupole mass spectrometry coupled to GC, LC, and IC addresses this challenge and maximizes coverage, providing the necessary specificity and sensitivity to meet regulatory guidelines.</p>
<h5><strong>3. SelectScience/Markes International: Target and non-target approaches for quality and safety testing of foods and beverages</strong></h5>
<ul>
<li>Tu, 15.11.2022, 17:00 (CET)</li>
</ul>
<p>We will discuss the innovative and green analytical strategies being adopted to ensure food quality and safety (SPME-GCxGC-TOF MS).</p>
<h5><strong>4. Wiley Analytical Science: How to Achieve Oil-Free Conditions in the Laboratory</strong></h5>
<ul>
<li>Th, 17.11.2022, 15:00 (CET)</li>
</ul>
<p>You will receive valuable tips on vacuum pumps for mass spectrometer system with less contamination, noise and energy consumption and learn how to achieve the optimal results for your application.</p>
<h5><strong>5. Separation Science/Agilent Technologies: Keep Running, Take the Lead: Integrated, Intuitive, GC &amp; GC/MS Intelligence</strong></h5>
<ul>
<li>Th, 17.11.2022, 16:00 (CET)</li>
</ul>
<p>Separation Science, in collaboration with Agilent, offers a webinar focusing on new technology advancements and best practices in GC/MS that reduce downtime and enhance lab productivity and performance.</p>
<h5><strong>6. Agilent Technologies: Analysis of Microplastics Has Never Been Easier</strong></h5>
<ul>
<li>Th, 17.11.2022, 20:00 (CET)</li>
</ul>
<p>Simple microplastic workflows will be discussed, featuring the 8700 LDIR and Cary 630.</p>
<h5><strong>7. Agilent Technologies: Handheld FTIR for in-field Chemical Analysis</strong></h5>
<ul>
<li>Fr, 18.11.2022, 18:00 (CET)</li>
</ul>
<p>This online seminar provides a comprehensive introduction to the FTIR in-field testing technology and Agilent TopScan 4300 Handheld spectrometer.</p>


Webinars LabRulezGCMS Week 46/2022

<p><strong>In the  week from November 21, 2022, the following webinars await you in the field of gas / solid phase and especially GC and GC/MS.</strong></p>
<blockquote>
<h4><a href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong>.</p>
</blockquote>
<h5><strong>1. VWR: Optimising GC method development</strong></h5>
<ul>
<li>Mo, 21.11.2022, 15:00 (CET)</li>
</ul>
<p>This webinar examines the critical GC method parameters that should be optimised to maximize separation selectivity and achieve resolution of target analytes.</p>
<h5><strong>2. Thermo Fisher Scientific: Accelerate discovery, enable success with personalized and flexible financial solutions and market competitive rates</strong></h5>
<ul>
<li>Tu, 22.11.2022, 11:00 (CET)</li>
</ul>
<p>Join this webinar and discover innovative equipment financing solutions that support your business goals and budget. </p>
<h5><strong>3. Agilent Technologies: Agilent 8890 Features to Improve Lab Productivity</strong></h5>
<ul>
<li>Tu, 22.11.2022, 17:00 (CEST)</li>
</ul>
<p>Have you been wondering how the new features in the 8890 can help your lab? Do you know the new features the 8890 has to offer?</p>
<h5><strong>4. Thermo Fisher Scientific: Ask-the-experts session on MOSH/MOAH analysis</strong></h5>
<ul>
<li>We, 23.11.2022, 11:00 (CET)</li>
</ul>
<p>Don´t miss this opportunity to ask our experts all your questions regarding the fully automated LC/GC workflow for MOAH/MOAH analysis.</p>
<h5><strong>5. Agilent Technologies: How to Minimize Compliance Risk in Regulated Laboratories</strong></h5>
<ul>
<li>Th, 24.11.2022, 11:00 (CET)</li>
</ul>
<p>During this webinar we will take a look at some of the latest trends and hot topics that are being observed within regulated laboratories.</p>


Webinars LabRulezGCMS Week 47/2022

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Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

The Faculty of Pharmacy, with its seat in the town of Hradec Králové, was established by a government decree in 1969. This Faculty of Pharmacy has continued in the old and long-time tradition of the education of pharmacy at Charles University.

Faculty of Pharmacy, Charles University

is the international joint scientific meeting to share recent developments, exchange ideas, explore new directions and initiate a possible collaboration in the analytical spectrometry area.

ESAS

The relatively new tradition of the Czech mass spectrometry conferences was established only in 2011, the very first event took place in Hradec Králové. Since then, the conference was organized every year except for 2020, the year of the pandemic.

Czech Mass Spectrometry Conferences

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

Webinars LabRulezGCMS Week 47/2022

Webinars LabRulezGCMS Week 46/2022

Webinars LabRulezGCMS Week 45/2022

Webinars LabRulezGCMS Week 44/2022

Webinars LabRulezGCMS Week 43/2022

ESAS-CSSC 2022 (Day 3)

Clarity software - Mass Spectrometry Extension

Webinars LabRulezGCMS Week 42-43/2022

6th STARSS Conference on Separation Science (Program)

Conference CEEPC/IPM/CMSC 2022 (Day 3)

Upcoming events

10th EuChemS Chemistry Congress (ECC10)

LECO Training Course Pegasus BT/BT4D BTX/BTX4D

Agilent Innovation Tour 2026

Webinars

Expert Answers: GC Troubleshooting and Method Development

Powering Energy Security and the Energy Transition: Advanced Analytical Solutions for Petroleum and Renewable Fuels

Basics. Principles of GC