<div><p><strong>In 2025, two outstanding young female researchers, Drs. Filipa Oliveira and Stella Gonsales, both originally from outside the Czech Republic, received prestigious JUNIOR STAR grants from the Czech Science Foundation (GAČR). JUNIOR STAR enables early career researchers to establish their own independent research groups and significantly advance their scientific careers. Their projects reflect cutting-edge research in materials science and sustainable chemistry, highlighting the international reach and welcoming research environment at UCT Prague.</strong></p><p><strong>Dr. Stella Gonsales is also a&nbsp;laureate of the Dagmar Procházková Fund, which supports promising scientific projects in sustainable and advanced organic chemistry. Another recipient of this grant is Dr.&nbsp;Anna Valunchene, whose research complements UCT Prague’s&nbsp;sustainability goals. This dual funding underlines Stella’s&nbsp;remarkable achievements and the wide scope of innovative research at UCT Prague.</strong></p><p><strong>Both Filipa and Stella are actively looking for motivated students and researchers to join their teams, offering a&nbsp;unique opportunity to work at the forefront of science in a&nbsp;vibrant and supportive environment.</strong></p></div><div><h3><strong>Interview with Filipa Oliveira: Pioneering tubular MXenes for supercapacitor energy storage</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_2_da6e538579.jpeg" alt="VŠCHT Prague: JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science: Filipa Oliveira" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_2_da6e538579.jpeg 235w," sizes="100vw" width="1500" height="999"></p><h5><strong>Congratulations on receiving the JUNIOR STAR grant. What does this achievement mean for you and how will it influence your next steps?</strong></h5><p>Thank you. It’s&nbsp;a huge achievement to receive this prestigious grant. It gives me the opportunity to establish my own research group here at UCT Prague. The JUNIOR STAR program supports talented young scientists in building their teams and accessing resources. This means I&nbsp;now have the support to focus fully on my research about tubular MXenes and their application in supercapacitors.</p><h5><strong>Why are tubular MXenes so innovative for energy storage?</strong></h5><p>MXenes are a family of 2D materials with a layered, accordion-like structure and known for their excellent electrical conductivity. Our innovation is to produce them with a tubular morphology, combining the high conductivity and redox activity in superior ion-transport tubular architectures. Their open, hollow structure increases surface area, ion diffusion and charge transport. This could translate to faster, more efficient supercapacitors, critical for sustainable energy technologies.</p><h5><strong>How did your scientific interest lead you to this field?</strong></h5><p>Global challenges around green energy made me focus on materials that can improve energy storage. MXenes stood out because changes in the composition and structure can significantly change their properties. I&nbsp;was curious about how tuning different metallic elements in a&nbsp;tubular morphology can impact how MXenes perform and how to optimize them for practical applications.</p><h5><strong>What challenges have you encountered?</strong></h5><p>One major challenge is their stability: MXenes oxidize quickly which deteriorates performance. Another challenge is understanding how synthesis conditions of both MXenes and their precursors (MAX phases) must be adapted to create and preserve tubular morphologies since their synthesis mechanisms differ from conventional MXenes. Additionally, effectively communicating the project in the funding proposal to show to reviewers why I&nbsp;should obtain this funding was also a&nbsp;challenge, but thanks to mentorship and collaboration, I&nbsp;overcame these hurdles.</p><h5><strong>What motivates you most about working at UCT Prague?</strong></h5><p>The support from colleagues and the excellent technical infrastructure make it a&nbsp;great place to work. Also, being a&nbsp;former member of Professor Sofer’s&nbsp;leading group in 2D&nbsp;materials is inspiring and led me to this achievement.</p><h5><strong>How do&nbsp;you see your professional development going in the future?</strong></h5><p>The grant will help me build my own team, acquire equipment, and develop collaborations. My long-term vision is to contribute significantly to sustainable energy solutions and scientific progress both locally and internationally.</p><h5><strong>You are looking for new team members. What kind of students or scientists do&nbsp;you need?</strong></h5><p>We are currently welcoming enthusiastic master's&nbsp;students, PhD candidates, and postdocs who are passionate about materials science and eager to explore new frontiers in MXenes and energy storage. If you love curiosity-driven research and want to be part of a&nbsp;growing international team, we encourage you to join us.</p><h3><strong>Interview with Stella Gonsales: Catalysis as a&nbsp;key to polymer recycling</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_3_3d0ded6274.jpeg" alt="VŠCHT Prague: JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science: Stella Gonsales" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_3_3d0ded6274.jpeg 233w," sizes="100vw" width="1499" height="1000"></p><h5><strong>Congratulations on your JUNIOR STAR grant and also being awarded the Dagmar Procházková Fund. What does receiving both mean to you and how will they shape your work?</strong></h5><p>Thank you. Both grants are hugely important. The JUNIOR STAR grant allows me to expand my group and resources for research into catalytic recycling of polymers, while the Dagmar Procházková Fund supports complementary projects such as synthesizing new biodegradable polymers. Together, they help tackle the plastic waste problem from multiple scientific angles.</p><h5><strong>Could you explain your research in layperson’s&nbsp;terms?</strong></h5><p>Most plastics have strong carbon-carbon bonds. We insert more cleavable double bonds into polymers that can be broken down by catalytic reactions called olefin metathesis, making recycling on a&nbsp;molecular level more feasible.</p><h5><strong>What makes the JUNIOR STAR grant particularly important for your research and career development?</strong></h5><p>The JUNIOR STAR grant is a&nbsp;prestigious and highly competitive funding opportunity aimed at excellent early-career scientists within eight years of completing a&nbsp;Ph.D. It provides up to 25&nbsp;million CZK over five years, allowing recipients to establish independent research groups and pursue innovative scientific topics. This grant is crucial for building a&nbsp;solid foundation, acquiring necessary equipment, and recruiting talented team members, enabling the pursuit of ambitious projects that can significantly contribute to both the Czech scientific community and global challenges.</p><h5><strong>What collaborations support your research?</strong></h5><p>The collaboration between UCT Prague and the Institute of Organic Chemistry and Biochemistry (IOCB) of the Czech Academy of Sciences primarily provides financial and technical support. The cooperation helps with funding, access to advanced equipment, and operational resources needed for running research projects.</p><h5><strong>What advice would you give young scientists aiming to succeed?</strong></h5><p>I&nbsp;encourage thinking outside the box and combining diverse knowledge you acquire during your career to address complex problems that are exciting and relevant to you.</p><h5><strong>Your laboratory bears the name of Otto Wichterle and was ceremonially opened in the presence of Professor Kamil Wichterle. How does Wichterle’s&nbsp;legacy inspire you personally?</strong></h5><p>Wichterle’<s>’</s>s&nbsp;innovative spirit motivates me to push creative boundaries and pursue novel solutions in sustainable chemistry.</p><h5><strong>What are your visions for the future?</strong></h5><p>I&nbsp;aim to build a&nbsp;research group that advances sustainable polymer recycling, contributing to environmental responsibility and the circular economy.</p><h5><strong>You are recruiting people for your team. What skills do&nbsp;they need to have?</strong></h5><p>We are looking for talented Ph.D. students and postdocs experienced in air-sensitive catalysis techniques. If you want to contribute to transformative research in sustainable chemistry and join a&nbsp;dynamic team, this is a&nbsp;great opportunity.</p></div>

JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science

News from LabRulezGCMS Library - Week 06, 2026

<p><strong>Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from deoxyribonucleic acid (DNA) into ribonucleic acid (RNA) can be initiated. The researchers focused on a specific class of molecules known as alarmones, which are found in cells across a wide range of organisms and whose levels often increase under conditions of cellular stress. The results were published in the prestigious scientific journal </strong><i><strong>Nature Chemical Biology</strong></i><strong>.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_bc2bfffa6c.jpg" alt="IOCB Prague/Tomáš Belloň: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: Dr. Hana Cahová, head of the Chemical Biology of Nucleic Acids research group." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_bc2bfffa6c.jpg 234w," sizes="100vw" width="2000" height="1335"></p><div><p>Molecules of ribonucleic acid can carry a variety of chemical modifications at one end, known as caps. In eukaryotic organisms, including human cells, the best-known cap plays an important role in RNA stability and in regulating its subsequent fate. In recent years, however, it has become clear that alternative, non-canonical RNA caps also exist, although their formation and the mechanisms by which they are attached to RNA remain only partially understood. These include alarmone caps, formed by dinucleoside polyphosphate molecules, that protect cellular RNA at moments when the cell is under threat.</p><p>In their study,<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://cahova.group.uochb.cz/en"><strong>Dr. Hana Cahová</strong></a> and colleagues examined bacterial RNA polymerase and investigated how this enzyme can initiate transcription using dinucleoside polyphosphates (NpNs) instead of the standard RNA building blocks. For the first time, the scientists described, at the atomic level, how RNA bearing an alarmone cap can be generated directly at the initiation of gene transcription. They also observed that NpNs bind through a different type of base pairing than is typically observed.</p><p>The work was significantly shaped by <strong>Valentina Serianni from Hana Cahová’s team</strong>, who demonstrated the ability of dinucleoside polyphosphates to initiate gene transcription, and by <strong>Jana Škerlová</strong>, who focused on the structural analysis of RNA polymerase. Using cryogenic electron microscopy data, she showed how dinucleoside polyphosphate molecules bind within the active site of RNA polymerase – that is, the core of the enzyme where genetic information is transcribed. Together, their findings help to elucidate the processes that accompany the transcription of genetic information from DNA to RNA.</p><p>Hana Cahová adds: <i>“We’re describing something that truly occurs in cells and that we’re now able to observe directly at the level of individual molecules. This allows us to answer fundamental questions about cellular processes, such as how cells adapt to stress. RNA plays a central role in this, as it carries the cascade of information underlying any cellular response – for example, to threatening conditions caused by nutrient deprivation or temperature shock.”</i></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_2_0fe88ff9e9.jpg" alt="IOCB Prague/Tomáš Belloň: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: Dr. Tomáš Kouba, head of the Cryogenic Electron Microscopy core facility." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_2_0fe88ff9e9.jpg 234w," sizes="100vw" width="2000" height="1335"></p><div><p>Cryogenic electron microscopy (cryo-EM) was central to the project. This part of the work was led by<strong> Dr. Tomáš Kouba</strong>, one of the authors of the study. <i>“Cryogenic electron microscopy allows us to freeze biological molecules in a state very close to their natural form and then determine their three-dimensional structure. This makes it possible to look directly into the active centers of enzymes and observe their function down to the atomic level,”</i> he explains.</p><p>Last year, IOCB Prague opened a new <a target="_blank" rel="noopener noreferrer" href="https://cryoem.group.uochb.cz/en"><strong>cryo-EM center</strong></a><strong> </strong>that is unique within the Czech research environment. State-of-the-art cryogenic electron microscopes are housed in a specially designed building and enable the study of biological processes with exceptional structural precision.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_3_4d881e7a58.jpg" alt="IOCB Prague: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: This work shows how NpnNs initiate bacterial transcription. Cryo-EM reveals how nucleobases pair with the template: one in canonical and one in reverse Watson–Crick mode, providing a structural basis for their function as non-canonical RNA caps." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_3_4d881e7a58.jpg 245w," sizes="100vw" width="2000" height="1077"></p><blockquote><h4><strong>The Original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41589-025-02134-5"><strong>Molecular insight into 5′ RNA capping with Np<sub>n</sub>Ns by bacterial RNA polymerase</strong></a></h4><p>Valentina M. Serianni, Jana Škerlová, Anna Knopp Dubánková, Anton Škríba, Hana Šváchová, Tereza Vučková, Anatolij Filimoněnko, Milan Fábry, Pavlína Řezáčová, Tomáš Kouba &amp; Hana Cahova&nbsp;</p><p>Nat. Chem. Biol. 21 (2026)</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1038/s41589-025-02134-5">https://doi.org/10.1038/s41589-025-02134-5</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><h4><strong>Abstract</strong></h4><p>RNA capped with dinucleoside polyphosphates has been discovered in bacteria and eukaryotes only recently. The likely mechanism of this specific capping involves direct incorporation of dinucleoside polyphosphates by RNA polymerase as noncanonical initiating nucleotides. However, how these compounds bind into the active site of RNA polymerase during transcription initiation is unknown. Here, we explored transcription initiation in vitro, using a series of DNA templates in combination with dinucleoside polyphosphates and model RNA polymerase from <i>Thermus</i> <i>thermophilus</i>. We observed that the transcription start site can vary on the basis of the compatibility of the specific template and dinucleoside polyphosphate. Cryo-electron microscopy structures of transcription initiation complexes with dinucleoside polyphosphates revealed that both nucleobase moieties can pair with the DNA template. The first encoded nucleotide pairs in a canonical Watson–Crick manner, whereas the second nucleobase pairs noncanonically in a reverse Watson–Crick manner. Our work provides a structural explanation of how dinucleoside polyphosphates initiate RNA transcription.</p></div></div>

Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription

Article

Application

Scientists

Science and research

Video

The University of Chemistry and Technology, Prague is a natural centre of first-rate study and research in the area of chemistry in Czechia and is one of the country's largest educational and research institutions focused on technical chemistry, chemical and biochemical technologies, material and chemical engineering, food chemistry, and environmental studies.

UCT Prague

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Thermo Scientific TraceGOLD™ TG-624 and TG-624SilMS GC Columns

Analyze residual solvents, volatile organic compounds, alcohols, and oxygenates using Thermo Scientific™ TraceGOLD™ TG-624 and TG-624SilMS GC Columns.

<p><strong>Analyze residual solvents, volatile organic compounds, alcohols, and oxygenates using Thermo Scientific™ TraceGOLD™ TG-624 and TG-624SilMS GC Columns. Both phases offer the low to mid polarity phase, 6% cyanopropylphenyl methypolysiloxane.</strong></p><ul><li><strong>TraceGOLD TG-624 GC Columns </strong>provide 90+% resolution of the first six gases in EPA Method 8260 and EPA Method 524.4. These columns are also ideal for EPA Methods 624 and 608.</li><li><strong>TraceGOLD TG-624SilMS GC Columns</strong> provide high thermal stability with maximum temperatures up to 320°C, which is ideal for volatile organics analysis. They are highly inert, providing excellent peak shape for a wide range of compounds.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Trace_GOLD_TG_624_and_TG_624_Sil_MS_GC_Columns_d515fd8ed9.jpg" alt="Thermo Scientific: TraceGOLD™ TG-624 and TG-624SilMS GC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Trace_GOLD_TG_624_and_TG_624_Sil_MS_GC_Columns_d515fd8ed9.jpg 244w," sizes="100vw" width="650" height="416"></p><h4><strong>Applications:</strong></h4><ul><li>Alcohols</li><li>Volatile organic compounds</li><li>Oxygenates</li><li>Residual solvents</li></ul>

Thermo Scientific TraceGOLD TG-17MS GC Columns

Thermo Scientific™ TraceGOLD TG-17MS GC Columns are particularly suited for GCMS applications that require more polarity than a 5% phenyl column.

<p><strong>Thermo Scientific™ TraceGOLD TG-17MS GC Columns are particularly suited for GCMS applications that require more polarity than a 5% phenyl column.</strong></p><ul><li>Mid-polarity phase of 50% diphenyl/50% dimethyl polysiloxane</li><li>Ideal for confirmational analysis</li><li>Excellent inertness for active compounds such as pesticides</li><li>Very low-bleed ideal for analysis by GCMS<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_17_MS_GC_columns_ad70df875d/Pragolab-GC-kolona-TraceGOLD-TG-17MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD TG-17MS GC Columns" width="1331" height="817"></figure><h4><strong>Recommended for:</strong></h4><ul><li>Pesticides and herbicides</li><li>Rosin acids</li><li>Phthalate esters</li><li>Triglycerides</li><li>Sterols</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rxi™-17</li><li>DB-17</li><li>DB-608</li><li>VF-17ms</li><li>CP-Sil 24 CB</li></ul>

Thermo Scientific TraceGOLD TG-1701MS GC Columns

Thermo Scientific™ TraceGOLD TG-1701MS GC Columns feature a mix of cyano and phenyl groups for increased polarity and a different elution order

<p><strong>Thermo Scientific™ TraceGOLD TG-1701MS GC Columns feature a mix of cyano and phenyl groups for increased polarity and a different elution order relative to less polar columns.</strong></p><ul><li>Mid-polarity phase (14% cyanopropylphenyl, 86% dimethyl polysiloxane)</li><li>Fully characterized for long-term reproducibility, column-to-column consistency and low-bleed</li><li>Optimal for confirmation analysis</li><li>Equivalent to USP G46 phase<br><br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1319/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_1701_MS_GC_columns_eee6a3200d/Pragolab-GC-kolona-TraceGOLD-TG-1701MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD TG-1701MS GC Columns" width="1319" height="817"></figure><h4><strong>Recommended for:</strong></h4><ul><li>Alcohols</li><li>Pesticides</li><li>Oxygenates</li><li>PCB cogeners</li><li>Aroclor mixes</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx-1701</li><li>DB-1701</li><li>HP-1701</li><li>SPB-1701</li><li>VF-1701</li><li>CP-Sil 19 CB</li></ul>

Thermo Scientific TraceGOLD™ TG-17SilMS GC Columns

Thermo Scientific™ TraceGOLD™ TG-17SilMS GC Column has the stability and performance profile ideal for separation of active environmental compounds such as polycyclic aromatic hydrocarbons

<p><strong>Optimize separation when analyzing active environmental compounds with the Thermo Scientific™ TraceGOLD™ TG-17SilMS GC Column.&nbsp;</strong></p><p>The column has the stability and performance profile ideal for separation of active environmental compounds such as polycyclic aromatic hydrocarbons (PAHs). Superior inertness ensures excellent peak shape and sensitivity.</p><p><strong>Engineered for Superior Performance</strong></p><ul><li>Midpolarity phase similar to 50% phenyl methylpolysiloxane</li><li>High thermal stability — maximum temperatures up to 340° to 360°C<br><br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_17_Sil_MS_GC_columns_433dd5a774/Pragolab-GC-kolona-TraceGOLD-TG-17SilMS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD TG-17SilMS GC Columns" width="1331" height="817"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>A low-bleed, stable column produces consistent results</li><li>Low baseline noise enables improved limits of detection with enhanced resolution of low level analytes</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility</li></ul><h4><strong>Applications</strong></h4><ul><li>PAHs</li><li>Pesticides and herbicides</li><li>Phthalate esters</li><li>Triglycerides</li></ul><h4><strong>Alternative Uses</strong></h4><ul><li>Triglycerides</li><li>Ketones</li><li>Nitroaromatics</li><li>Plant sterols</li><li>Pyrethroids</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-17ms</li><li>VF-17ms</li><li>CP-Sil 24 CB</li><li>ZB-50</li><li>BPX-50</li></ul>

Thermo Scientific TraceGOLD™ TG-225MS GC Columns

Achieve higher thermal stability and increased efficiency using the Thermo Scientific™ TraceGOLD™ TG-225MS GC Columns.

<p><strong>Achieve higher thermal stability and increased efficiency using the Thermo Scientific<sup>TM</sup> TraceGOLD<sup>TM</sup> TG-225MS GC Columns.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar phase, 50% cyano propylmethyl/50% phenylmethyl polysiloxane</li><li>Innovative deactivation process for siloxane to reduce tailing and improves efficiency over comparable columns</li><li>Equivalent to USP G7, G19 phases<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_225_MS_GC_columns_3085e09816/Pragolab-GC-kolona-TraceGOLD-TG-225MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-225MS GC Columns" width="1331" height="817"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Alditol acetates (sugars)</li><li>FAMEs</li><li>Alternative Uses:</li><li>Ketones</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx™-225</li><li>DB-225</li><li>HP-225</li><li>SPB™-225</li></ul>

Thermo Scientific Compound Discoverer software

Compound Discoverer software addresses small molecule identification needs and workflows including untargeted metabolomics, drug metabolism, impurity, E&L, environmental, food & beverage, and forensic research.

Thermo Scientific TraceGOLD™ TG-200MS GC Columns

Resolve compounds that phenyl and cyano phases cannot using the Thermo Scientific™ TraceGOLD™ TG-200MS GC Column. 

<p><strong>Resolve compounds that phenyl and cyano phases cannot using the Thermo Scientific™ TraceGOLD™ TG-200MS GC Column. The TraceGOLD TG-200MS column has an exceptionally inert phase with selectivity and elution order optimized for difficult separations.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar phase, trifluoropropylmethyl polysiloxane solid phase to resolve compounds that phenyl and cyano phases cannot</li><li>Outstanding thermal stability and low bleed</li><li>Suitable for use with sensitive detectors including electrochemical detectors, nitrogen phosphorus detectors and mass spectrometers</li><li>Appropriate for use as a confirmation GC column<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_200_MS_GC_columns_3644b02ed8/Pragolab-GC-kolona-TraceGOLD-TG-200MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-200MS GC Columns" width="1331" height="817"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Solvents</li><li>Fluorocarbons</li><li>Alcohols and ketones</li><li>Silanes</li><li>Glycols</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Herbicides</li><li>Organochlorine pesticides</li><li>Phenols</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx™-200MS</li><li>DB-200</li><li>DB-210</li></ul>

Thermo Scientific TraceGOLD™ TG-WaxMS GC Columns

Analyze FAMEs with excellent thermal stability using the Thermo Scientific™ TraceGOLD™ TG-WaxMS GC Column.

<p><strong>Analyze FAMEs with excellent thermal stability using the Thermo ScientificTM TraceGOLDTM TG-WaxMS GC Column.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar phase, polyethylene glycol</li><li>Polar-deactivated surface that tightly binds polymer for excellent thermal stability</li><li>Resistive to oxidative damage and damage from strongly acidic or basic volatiles better than silicone solid phases<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_Wax_MS_GC_columns_8ee57e55f2/Pragolab-GC-kolona-TraceGOLD-TG-WaxMS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-WaxMS GC Columns" width="1331" height="817"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Aldehydes</li><li>Essential oils</li><li>Solvents</li><li>Xylenes</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Acids</li><li>Alcohols</li><li>Alcohols in beverages</li><li>Alditol acetates (sugars)</li><li>Amines–Aliphatic</li><li>Amines–Aromatic</li><li>Herbicides</li><li>Ketones</li><li>Nitroaromatics</li><li>Phenols</li><li>Volatiles</li></ul><h4><strong>Applications:</strong></h4><ul><li>Fatty acid methyl esters (FAMEs)</li><li>Flavor compounds and essential oils</li><li>Solvents</li><li>Xylene isomers</li><li>EPA Method 603 for Acrolein/Acrylonitrile</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-WAX</li><li>DB-WAXetr</li><li>HP-Wax</li><li>HP-Innowax</li><li>SUPELCOWAX™ 10</li><li>CP-Wax 52 CB</li><li>Stabilwax™</li><li>Rtx™-Wax</li><li>BP20</li><li>ZB-Wax</li><li>Optima™ Wax</li><li>AT™-Wax</li></ul>

Thermo Scientific TraceGOLD™ TG-WaxMS A GC Columns

Identify organic acids with high performance, sensitivity and reproducibility while preventing oxidative damage using Thermo Scientific™ TraceGOLD™ TG-WaxMS A GC column.

<p><strong>Identify organic acids with high performance, sensitivity and reproducibility while preventing oxidative damage using Thermo Scientific™ TraceGOLD™ TG-WaxMS A GC column.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar phase, acid-deactivated polyethylene glycol</li><li>Resists oxidative damage and adsorption of acids</li><li>Excellent peak shapes for high MW acids</li><li>Equivalent to USP G25, G35 phases<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1305/798;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_Wax_MS_A_GC_columns_c81b8bbcb3/Pragolab-GC-kolona-TraceGOLD-TG-WaxMS-A-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-WaxMS A GC Columns" width="1305" height="798"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Acids</li><li>Carboxylic acids</li><li>Organic acids</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Alcohols</li><li>Alcohols in beverages</li><li>Aldehydes</li><li>Alditol acetates (sugars)</li><li>Essential oils</li></ul><h4><strong>Applications:</strong></h4><ul><li>Organic acids</li><li>Free fatty acids</li><li>Alcohols</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-FFAP</li><li>HP-FFAP</li><li>Nukol™</li><li>OV™-351</li><li>CP-Wax 58 CB</li><li>Stabilwax™-DA</li><li>BP-21</li><li>Optima™ FFAP</li></ul>

Thermo Scientific TraceGOLD™ TG-WaxMS B GC Columns

Identify basic analytes with high performance, sensitivity, and reproducibility without derivatization or column priming using Thermo Scientific™ TraceGOLD™ TG-WaxMS B columns.

<p><strong>Identify basic analytes with high performance, sensitivity, and reproducibility without derivatization or column priming using Thermo Scientific™ TraceGOLD™ TG-WaxMS B columns.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar, base-deactivated polyethylene glycol phase</li><li>Reduced absorption and improved responsiveness for basic compounds</li><li>Not suitable for use with water or alcohols</li></ul><p><br>&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_Wax_MS_B_GC_columns_5941c8d641/Pragolab-GC-kolona-TraceGOLD-TG-WaxMS-B-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-WaxMS B GC Columns" width="1331" height="798"></p><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Amines–Aliphatic</li><li>Amines–Aromatic</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Alcohols</li><li>Alcohols in beverages</li><li>Aldehydes</li><li>Alditol acetates (sugars)</li><li>Essential oils</li></ul><h4><strong>Similar to:</strong></h4><ul><li>CAM</li><li>Carbowax™ Amine</li><li>CP Wax51</li><li>Stabilwax™-DB</li></ul>

Related content

Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription

JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science

News from LabRulezGCMS Library - Week 06, 2026