<div><p><strong>In 2025, two outstanding young female researchers, Drs. Filipa Oliveira and Stella Gonsales, both originally from outside the Czech Republic, received prestigious JUNIOR STAR grants from the Czech Science Foundation (GAČR). JUNIOR STAR enables early career researchers to establish their own independent research groups and significantly advance their scientific careers. Their projects reflect cutting-edge research in materials science and sustainable chemistry, highlighting the international reach and welcoming research environment at UCT Prague.</strong></p><p><strong>Dr. Stella Gonsales is also a&nbsp;laureate of the Dagmar Procházková Fund, which supports promising scientific projects in sustainable and advanced organic chemistry. Another recipient of this grant is Dr.&nbsp;Anna Valunchene, whose research complements UCT Prague’s&nbsp;sustainability goals. This dual funding underlines Stella’s&nbsp;remarkable achievements and the wide scope of innovative research at UCT Prague.</strong></p><p><strong>Both Filipa and Stella are actively looking for motivated students and researchers to join their teams, offering a&nbsp;unique opportunity to work at the forefront of science in a&nbsp;vibrant and supportive environment.</strong></p></div><div><h3><strong>Interview with Filipa Oliveira: Pioneering tubular MXenes for supercapacitor energy storage</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_2_da6e538579.jpeg" alt="VŠCHT Prague: JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science: Filipa Oliveira" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_2_da6e538579.jpeg 235w," sizes="100vw" width="1500" height="999"></p><h5><strong>Congratulations on receiving the JUNIOR STAR grant. What does this achievement mean for you and how will it influence your next steps?</strong></h5><p>Thank you. It’s&nbsp;a huge achievement to receive this prestigious grant. It gives me the opportunity to establish my own research group here at UCT Prague. The JUNIOR STAR program supports talented young scientists in building their teams and accessing resources. This means I&nbsp;now have the support to focus fully on my research about tubular MXenes and their application in supercapacitors.</p><h5><strong>Why are tubular MXenes so innovative for energy storage?</strong></h5><p>MXenes are a family of 2D materials with a layered, accordion-like structure and known for their excellent electrical conductivity. Our innovation is to produce them with a tubular morphology, combining the high conductivity and redox activity in superior ion-transport tubular architectures. Their open, hollow structure increases surface area, ion diffusion and charge transport. This could translate to faster, more efficient supercapacitors, critical for sustainable energy technologies.</p><h5><strong>How did your scientific interest lead you to this field?</strong></h5><p>Global challenges around green energy made me focus on materials that can improve energy storage. MXenes stood out because changes in the composition and structure can significantly change their properties. I&nbsp;was curious about how tuning different metallic elements in a&nbsp;tubular morphology can impact how MXenes perform and how to optimize them for practical applications.</p><h5><strong>What challenges have you encountered?</strong></h5><p>One major challenge is their stability: MXenes oxidize quickly which deteriorates performance. Another challenge is understanding how synthesis conditions of both MXenes and their precursors (MAX phases) must be adapted to create and preserve tubular morphologies since their synthesis mechanisms differ from conventional MXenes. Additionally, effectively communicating the project in the funding proposal to show to reviewers why I&nbsp;should obtain this funding was also a&nbsp;challenge, but thanks to mentorship and collaboration, I&nbsp;overcame these hurdles.</p><h5><strong>What motivates you most about working at UCT Prague?</strong></h5><p>The support from colleagues and the excellent technical infrastructure make it a&nbsp;great place to work. Also, being a&nbsp;former member of Professor Sofer’s&nbsp;leading group in 2D&nbsp;materials is inspiring and led me to this achievement.</p><h5><strong>How do&nbsp;you see your professional development going in the future?</strong></h5><p>The grant will help me build my own team, acquire equipment, and develop collaborations. My long-term vision is to contribute significantly to sustainable energy solutions and scientific progress both locally and internationally.</p><h5><strong>You are looking for new team members. What kind of students or scientists do&nbsp;you need?</strong></h5><p>We are currently welcoming enthusiastic master's&nbsp;students, PhD candidates, and postdocs who are passionate about materials science and eager to explore new frontiers in MXenes and energy storage. If you love curiosity-driven research and want to be part of a&nbsp;growing international team, we encourage you to join us.</p><h3><strong>Interview with Stella Gonsales: Catalysis as a&nbsp;key to polymer recycling</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_3_3d0ded6274.jpeg" alt="VŠCHT Prague: JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science: Stella Gonsales" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_3_3d0ded6274.jpeg 233w," sizes="100vw" width="1499" height="1000"></p><h5><strong>Congratulations on your JUNIOR STAR grant and also being awarded the Dagmar Procházková Fund. What does receiving both mean to you and how will they shape your work?</strong></h5><p>Thank you. Both grants are hugely important. The JUNIOR STAR grant allows me to expand my group and resources for research into catalytic recycling of polymers, while the Dagmar Procházková Fund supports complementary projects such as synthesizing new biodegradable polymers. Together, they help tackle the plastic waste problem from multiple scientific angles.</p><h5><strong>Could you explain your research in layperson’s&nbsp;terms?</strong></h5><p>Most plastics have strong carbon-carbon bonds. We insert more cleavable double bonds into polymers that can be broken down by catalytic reactions called olefin metathesis, making recycling on a&nbsp;molecular level more feasible.</p><h5><strong>What makes the JUNIOR STAR grant particularly important for your research and career development?</strong></h5><p>The JUNIOR STAR grant is a&nbsp;prestigious and highly competitive funding opportunity aimed at excellent early-career scientists within eight years of completing a&nbsp;Ph.D. It provides up to 25&nbsp;million CZK over five years, allowing recipients to establish independent research groups and pursue innovative scientific topics. This grant is crucial for building a&nbsp;solid foundation, acquiring necessary equipment, and recruiting talented team members, enabling the pursuit of ambitious projects that can significantly contribute to both the Czech scientific community and global challenges.</p><h5><strong>What collaborations support your research?</strong></h5><p>The collaboration between UCT Prague and the Institute of Organic Chemistry and Biochemistry (IOCB) of the Czech Academy of Sciences primarily provides financial and technical support. The cooperation helps with funding, access to advanced equipment, and operational resources needed for running research projects.</p><h5><strong>What advice would you give young scientists aiming to succeed?</strong></h5><p>I&nbsp;encourage thinking outside the box and combining diverse knowledge you acquire during your career to address complex problems that are exciting and relevant to you.</p><h5><strong>Your laboratory bears the name of Otto Wichterle and was ceremonially opened in the presence of Professor Kamil Wichterle. How does Wichterle’s&nbsp;legacy inspire you personally?</strong></h5><p>Wichterle’<s>’</s>s&nbsp;innovative spirit motivates me to push creative boundaries and pursue novel solutions in sustainable chemistry.</p><h5><strong>What are your visions for the future?</strong></h5><p>I&nbsp;aim to build a&nbsp;research group that advances sustainable polymer recycling, contributing to environmental responsibility and the circular economy.</p><h5><strong>You are recruiting people for your team. What skills do&nbsp;they need to have?</strong></h5><p>We are looking for talented Ph.D. students and postdocs experienced in air-sensitive catalysis techniques. If you want to contribute to transformative research in sustainable chemistry and join a&nbsp;dynamic team, this is a&nbsp;great opportunity.</p></div>

JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science

News from LabRulezGCMS Library - Week 06, 2026

<p><strong>Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from deoxyribonucleic acid (DNA) into ribonucleic acid (RNA) can be initiated. The researchers focused on a specific class of molecules known as alarmones, which are found in cells across a wide range of organisms and whose levels often increase under conditions of cellular stress. The results were published in the prestigious scientific journal </strong><i><strong>Nature Chemical Biology</strong></i><strong>.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_bc2bfffa6c.jpg" alt="IOCB Prague/Tomáš Belloň: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: Dr. Hana Cahová, head of the Chemical Biology of Nucleic Acids research group." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_bc2bfffa6c.jpg 234w," sizes="100vw" width="2000" height="1335"></p><div><p>Molecules of ribonucleic acid can carry a variety of chemical modifications at one end, known as caps. In eukaryotic organisms, including human cells, the best-known cap plays an important role in RNA stability and in regulating its subsequent fate. In recent years, however, it has become clear that alternative, non-canonical RNA caps also exist, although their formation and the mechanisms by which they are attached to RNA remain only partially understood. These include alarmone caps, formed by dinucleoside polyphosphate molecules, that protect cellular RNA at moments when the cell is under threat.</p><p>In their study,<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://cahova.group.uochb.cz/en"><strong>Dr. Hana Cahová</strong></a> and colleagues examined bacterial RNA polymerase and investigated how this enzyme can initiate transcription using dinucleoside polyphosphates (NpNs) instead of the standard RNA building blocks. For the first time, the scientists described, at the atomic level, how RNA bearing an alarmone cap can be generated directly at the initiation of gene transcription. They also observed that NpNs bind through a different type of base pairing than is typically observed.</p><p>The work was significantly shaped by <strong>Valentina Serianni from Hana Cahová’s team</strong>, who demonstrated the ability of dinucleoside polyphosphates to initiate gene transcription, and by <strong>Jana Škerlová</strong>, who focused on the structural analysis of RNA polymerase. Using cryogenic electron microscopy data, she showed how dinucleoside polyphosphate molecules bind within the active site of RNA polymerase – that is, the core of the enzyme where genetic information is transcribed. Together, their findings help to elucidate the processes that accompany the transcription of genetic information from DNA to RNA.</p><p>Hana Cahová adds: <i>“We’re describing something that truly occurs in cells and that we’re now able to observe directly at the level of individual molecules. This allows us to answer fundamental questions about cellular processes, such as how cells adapt to stress. RNA plays a central role in this, as it carries the cascade of information underlying any cellular response – for example, to threatening conditions caused by nutrient deprivation or temperature shock.”</i></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_2_0fe88ff9e9.jpg" alt="IOCB Prague/Tomáš Belloň: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: Dr. Tomáš Kouba, head of the Cryogenic Electron Microscopy core facility." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_2_0fe88ff9e9.jpg 234w," sizes="100vw" width="2000" height="1335"></p><div><p>Cryogenic electron microscopy (cryo-EM) was central to the project. This part of the work was led by<strong> Dr. Tomáš Kouba</strong>, one of the authors of the study. <i>“Cryogenic electron microscopy allows us to freeze biological molecules in a state very close to their natural form and then determine their three-dimensional structure. This makes it possible to look directly into the active centers of enzymes and observe their function down to the atomic level,”</i> he explains.</p><p>Last year, IOCB Prague opened a new <a target="_blank" rel="noopener noreferrer" href="https://cryoem.group.uochb.cz/en"><strong>cryo-EM center</strong></a><strong> </strong>that is unique within the Czech research environment. State-of-the-art cryogenic electron microscopes are housed in a specially designed building and enable the study of biological processes with exceptional structural precision.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_3_4d881e7a58.jpg" alt="IOCB Prague: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: This work shows how NpnNs initiate bacterial transcription. Cryo-EM reveals how nucleobases pair with the template: one in canonical and one in reverse Watson–Crick mode, providing a structural basis for their function as non-canonical RNA caps." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_3_4d881e7a58.jpg 245w," sizes="100vw" width="2000" height="1077"></p><blockquote><h4><strong>The Original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41589-025-02134-5"><strong>Molecular insight into 5′ RNA capping with Np<sub>n</sub>Ns by bacterial RNA polymerase</strong></a></h4><p>Valentina M. Serianni, Jana Škerlová, Anna Knopp Dubánková, Anton Škríba, Hana Šváchová, Tereza Vučková, Anatolij Filimoněnko, Milan Fábry, Pavlína Řezáčová, Tomáš Kouba &amp; Hana Cahova&nbsp;</p><p>Nat. Chem. Biol. 21 (2026)</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1038/s41589-025-02134-5">https://doi.org/10.1038/s41589-025-02134-5</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><h4><strong>Abstract</strong></h4><p>RNA capped with dinucleoside polyphosphates has been discovered in bacteria and eukaryotes only recently. The likely mechanism of this specific capping involves direct incorporation of dinucleoside polyphosphates by RNA polymerase as noncanonical initiating nucleotides. However, how these compounds bind into the active site of RNA polymerase during transcription initiation is unknown. Here, we explored transcription initiation in vitro, using a series of DNA templates in combination with dinucleoside polyphosphates and model RNA polymerase from <i>Thermus</i> <i>thermophilus</i>. We observed that the transcription start site can vary on the basis of the compatibility of the specific template and dinucleoside polyphosphate. Cryo-electron microscopy structures of transcription initiation complexes with dinucleoside polyphosphates revealed that both nucleobase moieties can pair with the DNA template. The first encoded nucleotide pairs in a canonical Watson–Crick manner, whereas the second nucleobase pairs noncanonically in a reverse Watson–Crick manner. Our work provides a structural explanation of how dinucleoside polyphosphates initiate RNA transcription.</p></div></div>

Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription

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The University of Chemistry and Technology, Prague is a natural centre of first-rate study and research in the area of chemistry in Czechia and is one of the country's largest educational and research institutions focused on technical chemistry, chemical and biochemical technologies, material and chemical engineering, food chemistry, and environmental studies.

UCT Prague

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

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Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer

Shimadzu UV-2600i Plus and UV-2700i Plus spectrophotometers deliver high performance with flexible wavelength ranges, advanced optics, and efficient software control.

<h4><strong>Versatile, Expandable Mid-Range UV Spectrophotometers for Diverse Applications</strong></h4><section><section><section><ul><li><strong>The UV-2600i Plus </strong>is a<strong> single monochromator system </strong>with an <strong>expandable wavelength range up to 1400 nm </strong>using an optional integrating sphere, making it adaptable for various needs.</li><li><strong>The UV-2700i Plus </strong>is a <strong>double monochromator system capable of 8-Abs measurements</strong>, ideal for low transmittance samples.</li></ul><p>Both models come equipped with the intuitive <strong>Shimadzu LabSolutions UV-Vis software</strong>, ensuring data integrity and ease of use. Additionally, these spectrophotometers can be <strong>scheduled to shut down or enter sleep mode </strong>to save power and lamp life, and can <strong>automatically wake up at a specified time</strong>, enhancing efficiency. Elevate your analysis with these versatile and efficient spectrophotometers.</p><h3><strong>Features</strong></h3><h3><strong>Perfect for a Wide Variety of Applications</strong></h3><p>The functionality of the <strong>UV-2600i Plus /2700i Plus</strong> can be freely expanded to suit the measurement objective. By accommodating a wealth of accessories, the system can address any user’s applications and a variety of situations. Thanks to intuitive operations, anyone can easily obtain the data required.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_e5efa72f19.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_e5efa72f19.jpg 245w," sizes="100vw" width="1040" height="561"></p><h5><strong>Single monochromator UV-2600i Plus</strong></h5><p><strong>A key feature</strong> of the UV-2600i Plus equipped with a single monochromator is its<strong> measurement wavelength range</strong>. By using the optional ISR-2600Plus Integrating Sphere attachment, the measurement wavelength range can be extended from<strong> 220 nm to 1400 nm</strong>, significantly expanding its applications.</p><p><strong>Integrating Sphere Enables Measurements to 1400 nm</strong></p><p>The<strong> UV-2600i Plus</strong> is equipped with <strong>Shimadzu's proprietary LO-RAY-LIGH™ grade diffraction grating</strong>, which achieves high efficiency and low stray light levels. By installing the ISR-2600Plus two-detector integrating sphere, the <strong>300 nm to 1100 nm</strong> wavelength range of conventional models can be extended to <strong>1400 nm</strong>. In addition, the UV-2600i achieves a significant noise reduction, and can accommodate measurements of solar cell anti-reflective films and polycrystalline silicon wafers.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_11_40f2d1e598.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_11_40f2d1e598.jpg 245w," sizes="100vw" width="365" height="228"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_12_b71fa50d8f.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_12_b71fa50d8f.jpg 245w," sizes="100vw" width="1052" height="433"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_13_6adf0a1565.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_13_6adf0a1565.jpg 245w," sizes="100vw" width="1052" height="466"></p><h4><strong>Measures Slight Differences in Absorbance</strong></h4><p>Equipped with a double monochromator that achieves ultra-low stray light levels, the <strong>UV-2700i Plus</strong> is optimal for measuring low transmittance samples, such as polarization films used for LCD panels. The UV-2700i Plus is capable of <strong>8 Abs measurements</strong>, and can make accurate transmittance measurements to 1 part in 100 million, accommodating a variety of sample measurements.</p><p><strong>Achieves Ultra-Low Stray Light, Enabling 8-Abs Measurements</strong></p><p>In the case of a device equipped with a general double monochromator, the absorbance that can be covered is about<strong> </strong>5 to 6, but the UV-2700i Plus offers a range to 8 Abs, with a transmittance value of <strong>0.000001 %</strong> (1 part in 100 million). This system achieves high-level absorbance measurements with incomparable precision. In addition to measuring even high-concentration samples as is, eliminating the need to dilute samples, the system can be applied to evaluating the transmission characteristics of polarization films. Wavelengths in the<strong> 400 nm to 650 nm range</strong> can be measured to 8 Abs.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_16_a08f314ee7.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_16_a08f314ee7.jpg 164w," sizes="100vw" width="511" height="485"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_14_0d004ee208.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_14_0d004ee208.jpg 245w," sizes="100vw" width="1052" height="466"></p><p><strong>Sample Polarization Film Measurement</strong></p><p>With the rotating film holder (image below), two film samples can be set on the same optical axis. In this example, the polarization film is rotated in the plane, and the transmittance is measured when the film transmits and blocks light.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_1_5ff393836a.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_1_5ff393836a.jpg 163w," sizes="100vw" width="397" height="381"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_2_f293cd4e0e.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_2_f293cd4e0e.jpg 184w," sizes="100vw" width="450" height="381"></p><h4><strong>Enables Compliance with ER/ES Regulations and Stronger Data Management</strong></h4><div><div><p><strong>Compatible with Validation from PC Software</strong></p><p>Validation can be implemented with PC software using UV validation software. In addition to simplifying daily inspections, this makes instrument performance checks and records management easier, enabling more secure regulatory compliance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_1900i_Plus_UV_VIS_spectrophotometer_18_1aa29e9a5d.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_1900i_Plus_UV_VIS_spectrophotometer_18_1aa29e9a5d.jpg 232w," sizes="100vw" width="450" height="302"></p><ul><li>Inspection results can not only be printed but also saved to a file, so the results can be called up later for confirmation.</li><li>The inspection parameters can also be saved to separate files for periodic and routine inspections and then called up for use.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_1900i_Plus_UV_VIS_spectrophotometer_19_7395087cba.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_1900i_Plus_UV_VIS_spectrophotometer_19_7395087cba.jpg 232w," sizes="100vw" width="450" height="302"></p><ul><li>The user can select confirmation of instrument performance indicators as per JIS K 0115 General rules for molecular absorptiometric analysis, as well as the general test methods in the Japanese Pharmacopeia. (Order inspection jigs and reagents separately.)</li></ul><p><i>Note: Optional validation software is required to support the US Pharmacopeia and European Pharmacopeia.</i></p><p><strong>Support for FDA 21 CFR Part 11, PIC/S GMP Guidelines and Other Regulations and Guidelines</strong></p><p>Ensuring the integrity of data (database management), including the user management, user authority management, and data audit trails required for compliance with <strong>FDA 21 CFR Part 11, PIC/S GMP guidelines</strong>, and <strong>other ER/ES regulations</strong> is possible.</p><p><strong>Option Software Assists with Regulation-Compliant Validation</strong></p><p>UV validation software assists with performing the measurements and calculations required for validation. The software is included standard with UV-2600i/2700i models. In addition to routine inspections, it can also be used to perform instrument validation that is compliant with Japanese, US, and European pharmacopoeias.</p><p><strong>Assist Function</strong></p><p>The instrument assists the user to ensure that measurements are performed using the correct procedure.*1</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_1900i_Plus_UV_VIS_spectrophotometer_10_a30e63a8a4.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_1900i_Plus_UV_VIS_spectrophotometer_10_a30e63a8a4.jpg 245w," sizes="100vw" width="1201" height="212"></p><p>*1 This function can be enabled/disabled.</p><p><strong>Shutdown/Wakeup Functions</strong></p><section><div><p>The instrument can be shut down, and put into sleep mode. Putting the instrument into sleep mode limits power consumption and helps preserve the lamp. After a long period of measurements, the instrument and software can automatically be shut down. After shutdown, the instrument can also be set to wake up automatically at a specified time. With this function, analysis can start the instant the user arrives at the laboratory.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_15_45b844fcc9.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_15_45b844fcc9.jpg 245w," sizes="100vw" width="781" height="258"></p></div></section><h3><strong>Applications</strong></h3><h4><strong>Electricity, Electronics, and Optics</strong></h4><p><strong>Band Gap Measurements for Compound Semiconductors</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_3_03d8793fe0.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: The diffuse reflection spectra for two types of compound semiconductors (red line: Culn0.5Ga0.5Se2, blue line: CulnSe2) used as solar cell materials were measured using the ISR-2600Plus integrating sphere. It is evident that the absorption edge (position where the reflectance drops) differs depending on the sample. This difference signifies a difference in the band gap* for these samples. (The samples were provided by Wada Laboratory, Faculty of Science and Technology, Ryukoku University.) The band gaps for the samples were calculated utilizing the Tauc method. The results obtained were 1.27 eV for Culn0.5Ga0.5Se2 (red line) and 0.99 eV for CulnSe2 (blue line).  *The term band gap refers to the energy difference between the top of the valence band, which is full of electrons, and the bottom of the conduction band, which does not contain electrons." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_3_03d8793fe0.jpg 222w," sizes="100vw" width="519" height="364"></p><h4><strong>Chemicals</strong></h4><p><strong>Thickness Measurements of Cling Films</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_4_a5e83ed3ad.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: Undulating interference waveforms sometimes occur if light is passed through a film. The film thickness of a sample can be determined by using these interference waveforms. The figure shows transmittance data for a cling film. A clear interference waveform is produced. Utilizing optional film thickness measurement software, the film thickness is calculated as 10.4 μm. (Caution) The sample's refractive index must be entered for the film thickness calculation." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_4_a5e83ed3ad.jpg 222w," sizes="100vw" width="1038" height="728"></p><h4><strong>Medicines</strong></h4><p><strong>Evaluating Thermal Stability (T<sub>m</sub>) Analysis of Oligonucleotide Therapeutics</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_5_c80d107f38.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: Oligonucleotide therapeutics samples (9 to 60 M) were analyzed using TMSPC™-8i and 1 mm optical path length cells. Since UV-2600i Plus /2700i Plus can measure over a wide dynamic range, it is possible to perform a thermal stability analysis of nucleic acid drugs by obtaining the Tm value from the melting curve." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_5_c80d107f38.jpg 222w," sizes="100vw" width="1038" height="728"></p><h4><strong>Construction</strong></h4><p><strong>Window Glass Transmission Measurements</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_6_41420fd6ba.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: Two types of window glass were measured utilizing the ISR-2600Plus integrating sphere. The sample shown by the red line is highly transparent to near-infrared light at 800 nm or more. The sample shown by the blue line, however, is apparently not very transparent to near-infrared light." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_6_41420fd6ba.jpg 222w," sizes="100vw" width="519" height="364"></p><h4><strong>Cosmetics</strong></h4><p><strong>Measurement of the Ultra Violet Protection Factor Assigned to Ultraviolet Protection Clothes</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_7_528f748880.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: The UV protection provided by clothes and an umbrella were analyzed by an ISR-2600Plus integrating sphere accessory. The transmittance spectrum of the umbrella (green) shows that very little UV radiation transmits through the umbrella. In regards to the clothing, the black areas block more UV radiation than do the white areas." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_7_528f748880.jpg 159w," sizes="100vw" width="474" height="465"></p><h4><strong>Textiles</strong></h4><p><strong>Total Transmittance Spectrum of CNF</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_8_adb8c09844.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: An ISR-2600Plus integrating sphere was used to measure the total transmittance spectrum of cellulose nanofiber (CNF). Depending on the raw materials used, spectra can vary, transparency can vary, and spectral tendencies in the ultraviolet region can vary." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_8_adb8c09844.jpg 222w," sizes="100vw" width="519" height="364"></p><h4><strong>Life Sciences</strong></h4><p><strong>DNA and Protein Measurements</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_9_40a6f16a7b.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: The red and blue lines are the absorption spectra for dsDNA and BSA (bovine serum albumin), respectively. The concentration values are 45 ng/μL for dsDNA and 2.2 mg/mL for BSA." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_9_40a6f16a7b.jpg 222w," sizes="100vw" width="519" height="364"></p><h4><strong>Foods</strong></h4><p><strong>Vitamin Measurements</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_10_c7f5e10b1e.jpg" alt="Shimadzu UV-2600i Plus, UV-2700i Plus UV-VIS-NIR Spectrophotometer: This shows the absorption spectra for riboflavin (vitamin B2). The sample concentrations are, in order from the highest absorbance, 0.08, 0.04, 0.02, and 0.01 mg/mL." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Shimadzu_UV_2600i_Plus_UV_2700i_Plus_UV_VIS_NIR_Spectrophotometer_10_c7f5e10b1e.jpg 222w," sizes="100vw" width="1038" height="728"></p></div></div></section></section></section>

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