GC column trimming helps resolve contamination, ghost peaks, baseline instability, and peak tailing. Learn key symptoms and the correct technique for proper column cutting.

Guidance on selecting key GC column parameters — length, internal diameter, and film thickness — and their influence on resolution, retention, run time, and sample capacity.

Proper drying of the SPE sorbent is a critical step to achieve high sensitivity, good reproducibility, and maximum analyte recovery, especially for complex sample matrices.

How can you extend GC column lifetime and prevent contamination? Part 2 focuses on using liners with glass wool and proper column bake-out to maintain separation performance.

Dirty samples can quickly damage your GC column and shorten its lifetime. Learn simple, proven ways to protect your column, improve performance, and reduce downtime. Part 1 focuses on smart sample preparation.

An SPE technical tip focused on identifying the sources of interferences and extra peaks observed after sample extraction.

Although 100% recovery is expected in SPE, values above 100% are sometimes observed. This article explains the most common causes and provides practical guidance on how to identify and resolve them.

A technical guide to troubleshooting low analyte recovery in SPE. Explains relative vs. absolute recovery and provides practical solutions for conditioning, loading, and sorbent selection.

How can neutral analytes be efficiently concentrated in the presence of ionized acidic or basic contaminants? This SPE tip explains how mixed-mode cartridges improve selectivity and cleanup.

A clear guide to Normal Phase SPE: when to use it, how polar interactions drive retention, and which solvents to choose in increasing polarity—plus a quick reference list for optimized sample preparation.