Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 6th April 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies, BaySpec, poster by MDCW / William &amp; Mary and brochure by Shimadzu!<h3>1. Agilent Technologies: High-Throughput BTEX Analysis in Nail Products by SPME and GC/TQ</h3>Minimal steps, maximum precision<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_btex_analysis_nail_products_spme_gctq_5994_9009en_agilent_24ef32dd13.pdf">Full PDF for download</a></li></ul>BTEX compounds—benzene, toluene, ethylbenzene, and xylenes—are volatile aromatic hydrocarbons widely used as solvents in industrial and consumer products. Among these, toluene is the most prevalent in nail polish formulations, where it serves as a solvent to dissolve resins and pigments, ensuring smooth application, uniform color dispersion, and rapid drying. Historically, these properties made toluene a preferred ingredient in nail coatings, including traditional polishes, gel formulations, and nail art products. However, its inclusion presents challenges for regulatory compliance and product reformulation. In response to these challenges, the California Department of Toxic Substances Control (DTSC) has listed nail products containing toluene as Priority Products under the Safer Consumer Products Regulations.1 Manufacturers selling such products in California must submit a Priority Product Notification and conduct an Alternative Analysis if toluene concentrations exceed the 100-ppm threshold.&nbsp;To support compliance and ensure accurate monitoring of BTEX levels in nail products, robust analytical methods are essential. Solid phase microextraction (SPME) coupled with gas chromatography/triple quadrupole mass spectrometry (GC/TQ) has emerged as a preferred approach for volatile organic compound analysis due to its solvent-free sample preparation, high sensitivity, and compatibility with complex cosmetic matrices. The 8890 GC with 7000 Series GC/TQ offers enhanced detection capabilities through dynamic multiple reaction monitoring (dMRM), enabling precise quantification of BTEX compounds at trace levels, below regulatory thresholds. This platform provides the analytical rigor required for method validation, including limits of detection, recovery, and precision, ensuring compliance with California's stringent performance criteria and supporting industry efforts toward improving consumer product&nbsp;quality.&nbsp;<h4>Experimental</h4><h5>GC/TQ analysis&nbsp;</h5>Analyses were performed on an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890+GC">8890 GC</a> coupled to a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7000">7000 Series GC/TQ </a>equipped with an EI extractor ion source (Figure 2). The instrument operating parameters are listed in Table 2. The system was operated in splitless mode with an inlet temperature of 200&nbsp;°C, a purge flow of 3 mL/min, and a purge flow to split vent of 50&nbsp;mL/min at 2&nbsp;minutes. Carrier gas was helium at a constant flow of 0.693&nbsp;mL/min with a total flow of 53.7 mL/min. The chromatographic separation was accomplished on an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=DB-624+Ultra+Inert+column">Agilent J&amp;W DB-624 Ultra Inert column</a> (20&nbsp;m × 0.18&nbsp;mm, 1&nbsp;µm, part number 121-1324UI). The oven program started at 40&nbsp;°C (hold 2&nbsp;minutes), ramped at 35&nbsp;°C/min to 160&nbsp;°C, and held for 2.58&nbsp;minutes, giving a total run time of 8.0&nbsp;minutes. The transfer line was maintained at 230&nbsp;°C, with the ion source at 230&nbsp;°C and quadrupoles at 150&nbsp;°C.<h4>Conclusion&nbsp;</h4>A rapid, high-throughput headspace‑SPME GC/TQ method was developed for quantifying BTEX in nail product matrices, using a 100-µm PDMS Agilent Smart SPME fiber on an Agilent 8890 GC with Agilent 7000 Series GC/TQ. The method provides solvent-free extraction, 8-minute chromatographic runs, and an ~11-minute total cycle time, enabling high-throughput analysis with robust selectivity in dMRM mode. Quality control results demonstrated mean recoveries of 100 to 107% with RSDs ≤ 8%, meeting method acceptance criteria for compliance-focused testing for toluene. Integration of Smart SPME automation and the intelligent features of the 8890 GC and 7000 Series GC/TQ allows a practical, defensible solution for routine laboratories monitoring BTEX in nail products. Calibration performance showed high linearity and low variance across the working ranges, with all compounds meeting initial calibration criteria via R² ≥ 0.995 or average RF RSD ≤ 20%. Combined with the short cycle time and automated fiber tracking, this workflow is ideally suited for routine compliance testing of BTEX in nail products using the 8890 GC and 7000&nbsp;Series GC/TQ.<h3>2. BaySpec: Detection of residual pesticides on fruits and vegetables using Portability miniature mass s pectrometer</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Bay_Spec_App_Note_Portability_Pesticides_4a7311fb3e.pdf">Full PDF for download</a></li></ul>Pesticides are used in a variety of different ways during the production of food. Ranging from preventing crop damage by insects, rodents and molds during growth to prolonging storage of food after harvest. Because of the frequent usage, the residual pesticides are often found in many agricultural products and their monitoring and control is an important step in achieving and maintaining overall food safety in the modern society.&nbsp;Mass spectrometry in connection with different separation techniques currently represents the main analytical approach for determination of residual pesticides in food. Traditionally, samples need to be collected and send to a laboratory for analysis using techniques such as GC-MS or HPLC-MS, which are costly and time-consuming. In addition, the conventional mass spectrometry usually requires laborious sample pretreatment, which does not allow for immediate in-situ sample determination. Presented here is an application of Thermal Desorption ElectroSpray Ionization (TD-ESI) for pesticide screening coupled to a portable mass spectrometer.&nbsp;TD-ESI is a mass spectrometry technique from the family of ambient ionization methods that utilizes very simple probing of different surfaces with no or limited sample pretreatment while it is still noted for its selective and sensitive detection capabilities. In TD-ESI a solid surface or a liquid sample is touched by a simple metallic probe that absorbs the analyte. The probe is then inserted into a heated tube and the desorbed analyte is carried by gas flow into an orthogonally mounted electrospray. The electrospraty plume extracts the analyte and further ionization and ion introduction follows the conventional electrospray mechanism.&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2219">Bayspec’s Portability mass spectrometer</a> is less than 10kg highly portable and battery operated linear ion trap mass spectrometer with atmospheric pressure inlet (API). When TD-ESI is combined with PortabilityTM then it is possible to perform fast in-field detection of analytes including residual pesticides, directly of the surfaces of fresh food products without any sample pre-treatment. Fast pesticide screening by Portability mass spectrometer can immediately disclose fake organic food products as well as to discover elevated levels of residual pesticides.&nbsp;TD-ESI-MS was used to rapidly screen residual pesticides on the surfaces of different fruits and vegetables. Direct sampling probe was used to introduce analytes from surfaces of unprocessed samples. Due to short analysis times (1-5s a sample), the technique allows for fast screening for applications in food and environmental safety. MS (as well as MS/MS) analyses can be performed on surface-residual pesticides at ppm and sub-ppm levels. The miniaturized TD-ESI ion source compatible with Portability is available from BaySpec. This ion source mounts on the Portability front inlet and does not require any additional support, external power or gases. The simple intuitive software interface is operated by touch screen and makes the instrument extremely easy to control. The external TD-ESI source is fully integrated into the main software environment and the hyphenated system is thus very user-friendly, does not require excessive training and can be operated by persons with no previous mass spectrometry experiences.<h3>3. MDCW / William &amp; Mary: Volatile Characterization of American Foulbrood Disease Using Comprehensive Two-Dimensional Gas Chromatography</h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/P_15_Christensen_39521e3391.pdf">Full PDF for download</a></li></ul>American foulbrood (AFB) is a deadly disease spread by Paenibacillus larvae bacterial spores, targeting the brood stage of Apis mellifera honey bees. Broods perish in a matter of days after exposure to the spores, forming infected colloidal scales in the hive that adult bees cannot remove. 1,2 The spores are extremely persistent and resistant to typical treatment methods, which standardized the immediate euthanasia of bees and destruction of the hive and associated equipment by burning. 3 In an effort to expedite identification of the spores, scent-detection dogs have been trained for use in apiaries. Furthermore, gammairradiation has been tested as a proposed treatment method as it would offer a nondestructive alternative to sterilization.The goals of this study were to use comprehensive two-dimensional gas chromatography – time-of-flight mass spectrometry (GC×GC-TOFMS) to characterize the volatiles associated with AFB disease for understanding scent detection and to measure the effectiveness of gamma-irradiation in sterilizing these volatiles.<h4>Methods</h4>Samples included blanks, material from healthy comb, aged unsterilized diseased scales, fresh unsterilized diseased scales, and diseased scales sterilized with the proposed treatment method of gamma-irradiation. These samples were stored in headspace vials (Figure 3) in the freezer when not in use. No sample preparation was required before injection with solidphase microextraction using the LPAL-3 (CTC Analytics).Analysis was performed using a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/37">Pegasus BT4D</a> (LECO Corporation) according to the parameters described below in Table 1. <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/41">ChromaTOF software</a> (LECO Corporation) was used to analyze the chromatographic data. Preliminary identifications were assigned to peaks using a minimum signal to noise of 200 and a minimum stick count of 3.<h4>Conclusions</h4>GC×GC-TOFMS can be used to distinguish the volatile profiles of A. mellifera samples at different stages of infection with AFB disease. Future Directions for Research:&nbsp;<ul><li>Discrimination of volatiles specific to AFB from non-specific volatiles&nbsp;</li><li>Characterization of AFB-specific volatiles for scent-detection purposes&nbsp;</li><li>Measurement of gamma-irradiation sterilization success in removing AFB volatiles</li></ul><h3>4. Shimadzu: Screening System for Phthalate Esters, Brominated Flame Retardants and Other Regulated Substances Py-Screener Ver.3</h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c146_e507_45f041b0d7.pdf">Full PDF for download</a></li></ul>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Py-Screener">Py-Screener™ Ver. 3</a> can screen for 7 types of phthalate esters and brominated flame retardants (PBBs, PBDEs), including substances regulated under the RoHS Directive. In addition, it can also test for PIP (3:1), which is regulated under the US TSCA (Toxic Substances Control Act), as well as UV-328, Dechlorane Plus (DP), and short-chain chlorinated paraffins (SCCPs) and medium-chain chlorinated paraffins (MCCPs), which are regulated under the Stockholm Convention (POPs Convention) on Persistent Organic Pollutants (POPs). These regulated compounds, thermally extracted from the sample by Pyrolysis-GC-MS (Py-GC-MS), are selectively detected and quantified. Py-Screener Ver. 3 consists of dedicated software for easy screening, special standard samples, and a sampling tool kit, making it simple to operate even for first-time users.<h5>Shimadzu Corporation’s Solutions for Complying with International Hazardous Substance Regulations</h5>When manufacturing and exporting products, it is necessary to comply with the chemical and hazardous substance regulations established by each country. Products contain many parts and use various materials and substances. Therefore, it is the manufacturer’s responsibility to manage the entire supply chain to ensure that harmful substances are not contained. Shimadzu Corporation provides analysis solutions that comply with these regulations.<h5>Applicable Systems and Software</h5><ul><li>GC-MS: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-QP2020+NX">GCMS-QP™2020 NX</a>, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-QP2020">GCMS-QP2020,</a> <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-QP2010+Ultra">GCMS-QP2010 Ultra</a></li><li>Pyrolyzer: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=42&amp;search=EGA%2FPY-3030D">EGA/PY-3030D</a> multi-shot pyrolyzer</li><li>Autosampler: AS-2020E, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=42&amp;search=AS-1020E">AS-1020E auto-shot sampler&nbsp;</a></li><li>GC-MS Workstation: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMSsolution">GCMSsolution</a>™ (Ver. 4.60SP2 or later) + <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=LabSolutions+Insight">LabSolutions Insight</a>™ (Ver. 5.0 or later)</li><li>Py Workstation: EGA-PY3030 program (Ver. 1.54 or later)</li></ul>

News from LabRulezGCMS Library - Week 15, 2026

Microplastics and Nanomaterials: Understanding Emerging Contaminants in Environmental Testing

<div><div><div>Our immune system is incredibly powerful: among other things, it can recognize and destroy cancer cells. But tumors can be just as effective at avoiding detection – they build “invisibility shields” to protect themselves from attack.</div></div><div>One breakthrough in cancer therapy has been immune checkpoint inhibitors (ICIs), drugs that reactivate immune T cells and help them fight tumors again. However, only about 20–50% of patients respond well to this treatment. Researchers are therefore seeking alternative therapeutic strategies. A small and well-known molecule called adenosine plays a key role in these efforts.When tumor cells are stressed or dying, they release ATP, which is normally a signal that something is wrong in the tissue. But in the tumor microenvironment, ATP gets rapidly broken down by two enzymes, CD39 and CD73. Released adenosine acts like a chemical “calm-down” signal, binds to immune cells (T cells, NK cells, and others), and tells them to slow down, reducing their ability to kill cancer cells. Targeting CD73 therefore represents a promising strategy for developing new cancer treatments.</div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Nove_latky_mohou_podporit_imunitni_system_v_boji_s_rakovinou_88c5e82cd5.jpeg" alt="IOCB Prague: Development of potent inhibitors to boost the immune system's ability to fight cancer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Nove_latky_mohou_podporit_imunitni_system_v_boji_s_rakovinou_88c5e82cd5.jpeg 245w," sizes="100vw" width="661" height="363">At IOCB Prague, interdisciplinary teams led by Jan Řezáč, Jan Konvalinka, and Michal Hocek used a newly developed high-throughput screening method to test over 5,000 compounds, identifying two ribonucleoside derivatives as promising CD73 inhibitors.The scientists then improved the compounds’ activity by carefully modifying the ribonucleoside scaffold with bulky (het)aryl groups. Further optimization improved the pharmacokinetic properties of these compounds, yielding inhibitors with low clearance, long half-life, high solubility, and strong selectivity over related enzymes such as CD39.In cellular experiments, the compounds reduced adenosine production in cancer cells, restored T cell activation, and showed no toxicity toward human fibroblasts. The most active compound showed a single-digit picomolar inhibition constant (Ki).These findings establish a strong foundation for further in vivo efficacy and combination studies, which will explore the therapeutic potential of this novel inhibitor class.<blockquote><h4>The Original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsptsci.5c00707">Potent Competitive Inhibitors of Ecto-5′-nucleotidase (CD73) based on 6-(Het)aryl-7-deazapurine Ribonucleoside 5′-O-Bisphosphonates</a></h4>Ugnė Šinkevičiu̅tė, Magdalena Šímová, Radek Staník, Lenka Poštová Slavětínská, Kristýna Blažková, Pavel Šácha, Martin Lepšík, Jan Řezáč, Jan Konvalinka, Tereza Ormsby, Michal Tichý, Michal HocekACS Pharmacol. Transl. Sci. 2026, 9, 1, 191–213<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsptsci.5c00707">https://pubs.acs.org/doi/10.1021/acsptsci.5c00707</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>CD73 generates immunosuppressive adenosine in the tumor microenvironment and is a promising target for cancer immunotherapy. We have designed and systematically studied diverse 2-substituted 7-deazapurine ribonucleoside 5′-O-bisphosphonates bearing a variety of (het)aryl groups at position 6 and discovered their highly potent and selective CD73 inhibition activity. The most active compounds (with single-digit picomolar Ki) contained bicyclic (het)aryl groups at position 6 in combination with chlorine at position 2. Further optimization of pharmacokinetic properties identified inhibitors with low clearance, long half-life, high solubility, and excellent selectivity over CD39 and NTPDase3. They effectively suppressed adenosine formation in MDA-MB-231 cells, rescued CD8+ T cell activation, and were nontoxic to human fibroblasts. Overall, their profile compares favorably with AB680, a CD73 inhibitor currently in phase I/II clinical trials.</div>

Development of potent inhibitors to boost the immune system's ability to fight cancer

Article

Application

Environment

Scientific article

Science and research

Poster

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

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LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Organomation NiGen GC/HC Nitrogen Generator

The NiGen GC/HC is available in both a basic and HC version which completely removes hydrocarbons using a Pt/Pd catalyzer. 

The NiGen GC/HC is available in both a basic and HC version which completely removes hydrocarbons using a Pt/Pd catalyzer. It is capable of distributing 500 mL/min with greater than 99.9995% purity. It's designed to be connected to a dedicated AirComp compressor (can be purchased separately).&nbsp;Parallel connection allows for up to 4 generators to be stacked in a tower configuration. It features a CPU with touch screen display, which can be linked to a generator using CAN-BUS. This enables monitoring of the operating status and provides access to the maintenance menu, alarm reports, and functional parameters. It is capable of supporting up to 12 FIDs or NPDs with makeup gas or up to 7 ECDs.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_Ni_Gen_GC_modular_configuration_75ae60afb0.jpg" alt="Organomation: NiGen GC - Modular configuration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_Ni_Gen_GC_modular_configuration_75ae60afb0.jpg 147w," sizes="100vw" width="727" height="768"><h4>Standard features</h4><ul><li>Modular configuration</li><li>Capacity to supply up to 12 FIDs/NPDs with makeup gas, or up to 7 ECDs or 5 S/S</li><li>Easy, "plug and play" integration with the dedicated Brezza series air compressor AirComp</li><li>Included Fast Start technology guarantees UHP after only 30 minutes</li><li>HC model includes Pt/Pd to remove up to .1ppm of THC</li><li>CPU with Touch Screen Display (connectable with CAN BUS) allows you to monitor the operational status</li><li>CPU also has an Ethernet output for PC connection&nbsp;</li></ul><h4>Specification</h4>Key Features:<ul><li>Flow Rate: 500 mL/min</li><li>Output Pressure: 0 – 87 PSI (0 – 6 bar)</li><li>Purity: &gt; 99.9995%</li><li>Total Hydrocarbons: &lt; 0.1 ppm (HC model only)</li></ul>Air Input Requirements:<ul><li>Particulates: ≤ 0.01 mm</li><li>Oil Vapors: ≤ 0.01 mg/m³</li><li>Moisture: ≤ 3 °C dew point (ATP)</li><li>Minimum Pressure: 8 bar</li><li>Flow Rate: 6 L/min</li></ul>Electrical Requirements:<ul><li>NiGen GC: 115/230 V ±10%, 50–60 Hz, 50 W</li><li>NiGen GC HC:<ul><li>115 V ±10%, 60 Hz, 200 W</li><li>230 V ±10%, 50 Hz, 200 W</li></ul></li></ul>Additional Specifications:<ul><li>Protection Index: IP20</li><li>Noise Level:<ul><li>&lt; 50 dBA for 98% of operation</li><li>&lt; 60 dBA briefly during cycling</li></ul></li><li>Operating Temperature: 40 °F to 100 °F (5 °C to 40 °C)</li><li>Environmental Humidity: Max 90% (non-condensing)</li><li>Maximum Altitude: 2000 m (6561.68 ft)</li></ul>Dimensions &amp; Weight:<ul><li>GC Model:<ul><li>Height: 15.8" (40 cm)</li><li>Weight: 63 lbs (28 kg)</li></ul></li><li>GC HC Model:<ul><li>Height: 18.6" (47 cm)</li><li>Weight: 70.5 lbs (32 kg)</li></ul></li><li>Width: 14.9" (38 cm)</li><li>Depth: 20.8" (53 cm)</li></ul>Pneumatic Connections:<ul><li>Compressed Air Inlet: G 1/8” female</li><li>Nitrogen Outlet: G 1/8” female</li></ul>Warranty: 2 years<h4>Accessories</h4><ul><li>AirComp oil free compressor</li><li>CPU: User interface with touch screen display Brezza version</li><li>Installation kit</li><li>Maintenance kit for 8,000 or 16,000 running hours</li></ul>

Organomation NiGen Micro Nitrogen Generator

The Organomation NiGen Micro delivers up to 4 L/min nitrogen with 99.5% purity, PSA technology, and scalable modular configuration.

The Organomation NiGen Micro is a compact nitrogen generator based on PSA (Pressure Swing Adsorption) technology, designed for laboratory applications requiring a stable nitrogen supply up to 4 L/min with purity up to 99.5%.The system is designed for plug &amp; play integration with the AirComp oil-free compressor (Brezza series) and supports parallel connection of up to four units for increased capacity.It features a CPU with touchscreen display, with CAN-BUS and Ethernet connectivity, enabling real-time monitoring, diagnostics, alarm reporting, and maintenance control.<h4>Key Features</h4><ul><li>Nitrogen flow up to 4 L/min</li><li>Purity up to 99.5%</li><li>PSA technology with Fast Purity process</li><li>Rapid high-purity nitrogen generation</li><li>Plug &amp; play integration with AirComp compressor</li><li>Parallel connection of up to 4 units</li><li>Touchscreen CPU with CAN-BUS communication</li><li>Ethernet connection for PC integration</li><li>Low noise operation (&lt;50 dBA)</li><li>Compact modular design</li></ul><h4>Standard Features</h4><ul><li>PSA nitrogen generator (Claind Fast Purity technology)</li><li>Touchscreen CPU</li><li>CAN-BUS communication</li><li>Ethernet interface</li><li>Modular stackable configuration</li><li>Compatibility with AirComp compressor</li></ul><h3>Technical Specifications</h3><h4>General</h4><ul><li>Model: NiGen Micro</li><li>Flow rate: 4 L/min</li><li>Purity: up to 99.5%</li><li>Technology: PSA (Pressure Swing Adsorption)</li></ul><h4>Output Parameters</h4><ul><li>Pressure: 0–6 bar (0–87 psi)</li><li>Dew point: &lt; -50 °C (±2 °C)</li></ul><h4>Air Input Requirements</h4><ul><li>Particles: ≤ 0.01 µm</li><li>Oil vapors: ≤ 0.01 mg/m³</li><li>Moisture: ≤ 3 °C dew point</li><li>Minimum pressure: 8 bar</li><li>Minimum flow: 18 L/min</li></ul><h4>Electrical</h4><ul><li>115/230 V, 50–60 Hz</li><li>Power consumption: 50 W</li></ul><h4>Operating Conditions</h4><ul><li>Temperature: 5–35 °C</li><li>Humidity: max 90% non-condensing</li><li>Max altitude: 2000 m</li></ul><h4>Noise</h4><ul><li>&lt;50 dBA (98% of operation)</li><li>&lt;60 dBA (short peaks)</li></ul><h4>Dimensions &amp; Weight</h4><ul><li>Dimensions: 47 × 38 × 53 cm</li><li>Weight: 28 kg</li></ul><h4>Connections</h4><ul><li>Compressed air inlet: G 1/8" female</li><li>Nitrogen outlet: G 1/8" female</li></ul><h4>Warranty</h4><ul><li>2 years</li></ul><h4>Accessories</h4><ul><li>AirComp oil-free compressor (Brezza series)</li><li>CPU interface (Brezza version)</li><li>Installation kit</li><li>Maintenance kit (8,000 / 16,000 hours)</li></ul>

Organomation NITRO Nitrogen Generator

The Organomation NITRO 35/70 delivers up to 70 L/min nitrogen with 99.99% purity, PSA technology, remote monitoring, and integrated storage.

The Organomation NITRO (NiGen Nitro 35 / 70) is a high-performance nitrogen generator based on PSA technology, designed for applications requiring flow rates up to 70 L/min and purity up to 99.99%.It is available in two models:<ul><li>NITRO 35 – up to 35 L/min</li><li>NITRO 70 – up to 70 L/min</li></ul>The system delivers a dew point below -50 °C and hydrocarbon levels below 0.01 ppm, making it suitable for demanding applications such as LC/MS.An integrated 24 L internal tank ensures stable nitrogen supply and reduces downtime. The unit features a touchscreen display, supports remote access via Claind4You, and enables full system integration using MODBUS, MQTT, and HTTPS protocols.<h4>Key Features</h4><ul><li>Two models: 35 and 70 L/min</li><li>Nitrogen purity up to 99.99%</li><li>Dew point &lt; -50 °C</li><li>Hydrocarbon content &lt; 0.01 ppm</li><li>PSA (Pressure Swing Adsorption) technology</li><li>24 L internal storage tank</li><li>Touchscreen display with monitoring and alerts</li><li>Remote control via Claind4You</li><li>Integration via MODBUS, MQTT, HTTPS</li><li>Automatic operation with leak detection</li><li>Mobile design with wheels</li><li>Reliable continuous operation</li></ul><h4>Available Models</h4><h5>NITRO 35</h5><ul><li>Flow rate: up to 35 L/min</li><li>Weight: 75 kg</li></ul><h5>NITRO 70</h5><ul><li>Flow rate: up to 70 L/min</li><li>Weight: 90 kg</li></ul><h4>Standard Features</h4><ul><li>PSA nitrogen generator (Claind technology)</li><li>Touchscreen display</li><li>Automatic operation with alarms</li><li>Alarm logging and diagnostics</li><li>24 L internal tank</li><li>Remote access (Claind4You)</li><li>Communication protocols (MODBUS, MQTT, HTTPS)</li><li>Wheels for mobility</li></ul><h3>Technical Specifications</h3><h4>General</h4><ul><li>Model: NiGen Nitro 35 / 70</li><li>Technology: PSA</li><li>Purity: up to 99.99%</li><li>Dew point: &lt; -50 °C</li><li>Hydrocarbons: &lt; 0.01 ppm</li><li>Output pressure: 0–6.5 bar (0–94 psi)</li></ul><h4>Flow Rate</h4><ul><li>NITRO 35: up to 35 L/min</li><li>NITRO 70: up to 70 L/min</li></ul><h4>Air Input Requirements</h4><ul><li>Particles: ≤ 0.01 µm</li><li>Oil: ≤ 0.01 mg/m³</li><li>Moisture: ≤ 3 °C dew point</li><li>Air flow:<ul><li>35: up to 90 L/min</li><li>70: up to 170 L/min</li></ul></li></ul><h4>Electrical</h4><ul><li>115 / 230 V</li><li>50–60 Hz</li><li>Power consumption: 200 W</li></ul><h4>Operating Conditions</h4><ul><li>Temperature: 5–40 °C</li><li>Humidity: 5–80%</li><li>Max altitude: 2000 m</li></ul><h4>Dimensions</h4><ul><li>92 × 26.5 × 75 cm</li></ul><h4>Weight</h4><ul><li>NITRO 35: 75 kg</li><li>NITRO 70: 90 kg</li></ul><h4>Communication</h4><ul><li>MODBUS (TCP), MQTT, HTTPS</li><li>Wi-Fi connectivity</li></ul><h4>Protection</h4><ul><li>IP20</li></ul><h4>Warranty</h4><ul><li>2 years</li></ul><h4>Accessories</h4><ul><li>100 L reservoir (air or nitrogen storage)</li><li>Installation kit for LC/MS (A200)</li><li>Dual Purity module (99.999% for LC-MS collision cell)</li></ul>

Organomation FLO Nitrogen Generator

The Organomation FLO provides adjustable nitrogen purity with integrated storage, real-time monitoring, and PSA technology for flexible lab applications.

The Organomation FLO (N2 FLO Series) is an advanced nitrogen generator based on PSA technology, designed for applications requiring flexible purity control and continuous operation.The system includes an oxygen analyzer and pressure regulator, enabling real-time nitrogen purity monitoring. Thanks to its integrated storage tank, no external buffer is required – one vessel serves both as buffer and supply reservoir.The generator automatically switches to energy-saving standby mode when production exceeds demand. An air quality analyzer (humidity and oil particles) ensures protection of the system and gas purity.The unit supports digital control and integration via MODBUS, MQTT, and HTTP protocols. An optional E941 food-grade configuration is available.<h4>Key Features</h4><ul><li>PSA technology (Claind Fast Purity)</li><li>Real-time nitrogen purity monitoring (O₂ analyzer)</li><li>Integrated storage tank (no buffer required)</li><li>Automatic standby mode for energy savings</li><li>Adjustable nitrogen purity</li><li>Digital control and communication (MODBUS, MQTT, HTTP)</li><li>Air quality protection (humidity, oil, particles)</li><li>Unattended continuous operation</li><li>Optional food-grade configuration (E941)</li></ul><h4>Available Models</h4><ul><li>N2 FLO 1</li><li>N2 FLO 2</li><li>N2 FLO 3</li><li>N2 FLO 4</li></ul><h4>Standard Features</h4><ul><li>PSA nitrogen generator</li><li>Oxygen analyzer</li><li>Pressure regulator</li><li>Digital control system</li><li>Integrated nitrogen tank</li><li>Air quality protection system</li><li>Communication interfaces (MODBUS, MQTT, HTTP)</li></ul><h3>Technical Specifications</h3><h4>General</h4><ul><li>Technology: PSA (Fast Purity)</li><li>Dew point: -50 °C</li><li>Output pressure: 1.5 bar below inlet pressure</li><li>Noise: ≤ 60 dB</li><li>Protection class: IP20</li></ul><h4>Electrical</h4><ul><li>115 / 230 V</li><li>50–60 Hz</li><li>Power consumption: 50 W</li></ul><h4>Operating Conditions</h4><ul><li>Temperature: 5–40 °C</li></ul><h4>Air Input Requirements</h4><ul><li>Pressure: 6.5–13 bar</li><li>Quality: ISO 8573-1 Class 1.4.1</li><li>Dry, clean, oil-free air</li></ul><h4>Dimensions</h4><ul><li>118 × 40 × 80 cm</li></ul><h4>Weight</h4><ul><li>FLO 1: 92 kg</li><li>FLO 2: 113 kg</li><li>FLO 3: 134 kg</li><li>FLO 4: 155 kg</li></ul><h4>Performance vs Purity (L/min at 8.5 bar, 20 °C)</h4><h5>N2 FLO 1</h5><ul><li>99.999%: 3 L/min</li><li>99.99%: 6 L/min</li><li>99.9%: 15 L/min</li><li>99.5%: 25 L/min</li><li>99%: 33 L/min</li><li>98%: 40 L/min</li><li>97%: 46 L/min</li></ul><h5>N2 FLO 2</h5><ul><li>99.999%: 8 L/min</li><li>99.99%: 13 L/min</li><li>99.9%: 30 L/min</li><li>99.5%: 48 L/min</li><li>99%: 60 L/min</li><li>98%: 76 L/min</li><li>97%: 88 L/min</li></ul><h5>N2 FLO 3</h5><ul><li>99.999%: 11 L/min</li><li>99.99%: 20 L/min</li><li>99.9%: 43 L/min</li><li>99.5%: 71 L/min</li><li>99%: 88 L/min</li><li>98%: 111 L/min</li><li>97%: 130 L/min</li></ul><h5>N2 FLO 4</h5><ul><li>99.999%: 16 L/min</li><li>99.99%: 28 L/min</li><li>99.9%: 61 L/min</li><li>99.5%: 96 L/min</li><li>99%: 120 L/min</li><li>98%: 151 L/min</li><li>97%: 176 L/min</li></ul>

Organomation MAXI Nitrogen Generator

The Organomation MAXI delivers high-capacity nitrogen generation with PSA technology, real-time monitoring, and scalable industrial performance.

The Organomation MAXI (N2 MAXI Series) is a high-capacity industrial nitrogen generator based on PSA Fast Purity technology, designed for applications requiring very high flow rates and stable nitrogen supply.The system includes an oxygen analyzer and pressure regulator, enabling real-time purity monitoring. Its integrated tank eliminates the need for a buffer vessel, combining storage and delivery in one system.The generator automatically switches to energy-saving standby mode when production exceeds consumption. An air quality monitoring system (humidity and oil) protects both performance and gas purity.Full IT integration is enabled via MODBUS, MQTT, and HTTP, with an optional E941 food-grade configuration.<h4>Key Features</h4><ul><li>PSA technology (Claind Fast Purity)</li><li>Very high flow rates (up to thousands L/min)</li><li>Real-time nitrogen purity monitoring</li><li>Integrated storage tank (no buffer required)</li><li>Automatic standby mode</li><li>Adjustable purity levels</li><li>Digital control with IT integration</li><li>Air quality protection system</li><li>Unattended continuous operation</li><li>Optional food-grade configuration (E941)</li></ul><h4>Available Models</h4><ul><li>N2 MAXI 1</li><li>N2 MAXI 2</li><li>N2 MAXI 3</li><li>N2 MAXI 4</li></ul><h4>Standard Features</h4><ul><li>PSA nitrogen generator</li><li>Oxygen analyzer</li><li>Pressure regulator</li><li>Digital control system</li><li>Integrated nitrogen tank</li><li>Air quality monitoring system</li><li>Communication interfaces (MODBUS, MQTT, HTTP)</li></ul><h3>Technical Specifications</h3><h4>General</h4><ul><li>Technology: PSA (Fast Purity)</li><li>Dew point: -50 °C</li><li>Output pressure: 1.5 bar below inlet pressure</li><li>Noise: ≤ 60 dB</li><li>Protection class: IP20</li></ul><h4>Electrical</h4><ul><li>115 / 230 V</li><li>50–60 Hz</li><li>Power consumption: 50 W</li></ul><h4>Operating Conditions</h4><ul><li>Temperature: 5–40 °C</li></ul><h4>Air Input Requirements</h4><ul><li>Pressure: 6.5–13 bar</li><li>Quality: ISO 8573-1 Class 1.4.1</li><li>Dry, clean, oil-free air</li></ul><h4>Dimensions</h4><ul><li>Height: 207.5 cm</li><li>Depth: 117 cm</li><li>Width:<ul><li>MAXI 1: 62 cm</li><li>MAXI 2: 103 cm</li><li>MAXI 3: 142 cm</li><li>MAXI 4: 182 cm</li></ul></li></ul><h4>Weight</h4><ul><li>MAXI 1: 730 kg</li><li>MAXI 2: 1400 kg</li><li>MAXI 3: 2050 kg</li><li>MAXI 4: 2700 kg</li></ul><h4>Performance vs Purity (L/min at 8.5 bar, 20 °C)</h4><h5>N2 MAXI 1</h5><ul><li>99.999%: 103 L/min</li><li>99.99%: 150 L/min</li><li>99.9%: 311 L/min</li><li>99.5%: 518 L/min</li><li>99%: 651 L/min</li><li>98%: 828 L/min</li><li>97%: 931 L/min</li></ul><h5>N2 MAXI 2</h5><ul><li>99.999%: 206 L/min</li><li>99.99%: 300 L/min</li><li>99.9%: 623 L/min</li><li>99.5%: 1,035 L/min</li><li>99%: 1,311 L/min</li><li>98%: 1,648 L/min</li><li>97%: 1,850 L/min</li></ul><h5>N2 MAXI 3</h5><ul><li>99.999%: 310 L/min</li><li>99.99%: 450 L/min</li><li>99.9%: 935 L/min</li><li>99.5%: 1,553 L/min</li><li>99%: 1,965 L/min</li><li>98%: 2,483 L/min</li><li>97%: 2,780 L/min</li></ul><h5>N2 MAXI 4</h5><ul><li>99.999%: 413 L/min</li><li>99.99%: 600 L/min</li><li>99.9%: 1,246 L/min</li><li>99.5%: 2,070 L/min</li></ul>

Organomation PICO Nitrogen Generator

The Organomation PICO delivers flexible nitrogen generation with adjustable purity, integrated storage, and real-time monitoring.

The Organomation PICO (N2 PICO Series) is a compact and high-performance nitrogen generator based on PSA Fast Purity technology, designed for applications requiring flexible purity control and stable nitrogen supply.The system includes an oxygen analyzer and pressure regulator, enabling real-time purity monitoring. Its integrated tank eliminates the need for a buffer vessel, combining storage and delivery in one unit.The generator automatically switches to energy-saving standby mode when production exceeds consumption. An air quality analyzer (humidity and oil particles) protects system performance and gas quality.The system supports digital control and integration via MODBUS, MQTT, and HTTP, with an optional E941 food-grade configuration.<h4>Key Features</h4><ul><li>PSA technology (Claind Fast Purity)</li><li>Real-time nitrogen purity monitoring</li><li>Integrated storage tank (no buffer required)</li><li>Automatic standby mode</li><li>Adjustable nitrogen purity</li><li>Digital control and communication (MODBUS, MQTT, HTTP)</li><li>Air quality protection system</li><li>Unattended continuous operation</li><li>Optional food-grade configuration (E941)</li></ul><h4>Available Models</h4><ul><li>N2 PICO 3</li><li>N2 PICO 4</li><li>N2 PICO 5</li><li>N2 PICO 6</li></ul><h4>Standard Features</h4><ul><li>PSA nitrogen generator</li><li>Oxygen analyzer</li><li>Pressure regulator</li><li>Digital control system</li><li>Integrated nitrogen tank</li><li>Air quality monitoring system</li><li>Communication interfaces (MODBUS, MQTT, HTTP)</li></ul><h3>Technical Specifications</h3><h4>General</h4><ul><li>Technology: PSA (Fast Purity)</li><li>Dew point: -50 °C</li><li>Output pressure: 1.5 bar below inlet pressure</li><li>Noise: ≤ 60 dB</li><li>Protection class: IP20</li></ul><h4>Electrical</h4><ul><li>115 / 230 V</li><li>50–60 Hz</li><li>Power consumption: 50 W</li></ul><h4>Operating Conditions</h4><ul><li>Temperature: 5–40 °C</li></ul><h4>Air Input Requirements</h4><ul><li>Pressure: 6.5–13 bar</li><li>Quality: ISO 8573-1 Class 1.4.1</li><li>Dry, clean, oil-free air</li></ul><h4>Dimensions</h4><ul><li>138 × 40 × 130 cm</li></ul><h4>Weight</h4><ul><li>PICO 3: 230 kg</li><li>PICO 4: 270 kg</li><li>PICO 5: 310 kg</li><li>PICO 6: 350 kg</li></ul><h4>Performance vs Purity (L/min at 8.5 bar, 20 °C)</h4><h5>N2 PICO 3</h5><ul><li>99.999%: 25 L/min</li><li>99.99%: 41 L/min</li><li>99.9%: 90 L/min</li><li>99.5%: 143 L/min</li><li>99%: 173 L/min</li><li>98%: 230 L/min</li><li>97%: 268 L/min</li></ul><h5>N2 PICO 4</h5><ul><li>99.999%: 33 L/min</li><li>99.99%: 55 L/min</li><li>99.9%: 115 L/min</li><li>99.5%: 191 L/min</li><li>99%: 250 L/min</li><li>98%: 306 L/min</li><li>97%: 345 L/min</li></ul><h5>N2 PICO 5</h5><ul><li>99.999%: 38 L/min</li><li>99.99%: 66 L/min</li><li>99.9%: 153 L/min</li><li>99.5%: 240 L/min</li><li>99%: 306 L/min</li><li>98%: 383 L/min</li><li>97%: 441 L/min</li></ul><h5>N2 PICO 6</h5><ul><li>99.999%: 58 L/min</li><li>99.99%: 83 L/min</li><li>99.9%: 173 L/min</li><li>99.5%: 288 L/min</li><li>99%: 365 L/min</li><li>98%: 460 L/min</li><li>97%: 518 L/min</li></ul>

Products from category Nitrogen generators from Organomation - page 1

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