Learn how to diagnose and fix retention time shifts in GC. This guide explains common column performance issues, their causes, and practical remedies for consistent chromatographic results.

Understanding GC column polarity and selectivity is key to achieving optimal separations. Learn how to choose the right stationary phase for your compounds and improve chromatographic performance.

Learn how to fix baseline offset in gas chromatography. Identify causes like voltage changes, contamination, or gas flow issues and apply targeted maintenance for stable results.

Negative peaks in GC can affect your analysis accuracy. Learn about the main causes, from detector overload to contamination, and how to correct them effectively.

Learn how to identify and fix sensitivity loss in GC. Discover key causes, from column contamination to injector leaks, and apply remedies for reliable, accurate results.

Practical troubleshooting guide for low recovery in SPE methods. Learn how to identify problems with solvents, flow rate, pH, or sorbent choice step by step.

Over-drying silica-based SPE cartridges during conditioning can reduce analyte retention and recovery. Learn best practices to avoid losses and ensure reproducible results.

Missing peaks in GC runs? This technical tip reviews key causes like syringe, inlet, detector, or column issues, with practical solutions to restore results.

Learn how to troubleshoot and fix broad solvent peaks/fronts in GC analysis with practical tips from Phenomenex to improve peak shape and accuracy.

GC column issues often arise from improper installation. The table below helps you diagnose and resolve common problems using your Column Performance Test Mixture.