<h3><strong>Introduction: Careers in GC/MS Analytical Chemistry</strong></h3><p><strong>Analytical chemists</strong> specializing in <strong>gas chromatography with mass spectrometry (GC/MS)</strong> work across diverse industries, including forensics, environmental monitoring, petrochemical analysis, food testing, and pharmaceutical QA/QC. Their role is to detect, quantify, and characterize volatile and semi-volatile compounds in complex matrices.</p><h4><strong>What is GC/MS?</strong></h4><p><strong>Gas chromatography-mass spectrometry (GC-MS)</strong> combines the separation power of <strong>gas chromatography</strong> with the detection and identification capabilities of <strong>mass spectrometry</strong>. GC separates components of gaseous or volatile samples, and MS provides molecular weight and structural insights. It's widely used for trace-level analysis of complex mixtures.</p><h4><strong>Key Global Manufacturers of GC/MS Systems</strong></h4><ul><li><strong>Agilent Technologies</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/324"><strong>Thermo Fisher Scientific</strong></a></li><li><strong>LECO Corporation</strong></li><li><strong>Shimadzu</strong></li><li><strong>Bruker</strong></li><li><strong>Sciex (Triple Quad GC/MS/MS)</strong></li></ul><h3><strong>Job Opportunities in GC/MS</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/career"><strong>Job details in the CAREER section</strong></a></p><p class="cke-user_style-important"><strong>👉Search and filter in the largest database with over 1,000 jobs in analytical chemistry and laboratory technologies.</strong></p></blockquote><h4>🌎<strong> North America</strong></h4><h5><strong>1. LECO Corporation: Telephone Service Engineer</strong></h5><ul><li>St. Joseph (MI), USA</li><li>Service engineer, Elementary analysis, GC-MS, GC</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2258"><strong>Job details can be found here</strong></a></li></ul><h5><strong>2. LECO Corporation: Demo Applications Chemist – Separation Science</strong></h5><ul><li>St. Joseph (MI), USA</li><li>Application Specialist, GC, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2079"><strong>Job details can be found here</strong></a></li></ul><h5><strong>3. LECO Corporation: Separation Science Field Service Engineer - Midwestern</strong></h5><ul><li>Midwestern, USA</li><li>Service engineer, GC, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2073"><strong>Job details can be found here</strong></a></li></ul><h5><strong>4. Shimadzu: Field Sales Engineer</strong></h5><ul><li>South Carolina – Western North Carolina, USA</li><li>Sales Representative, LC, LC-MS, GC, GC-MS, Spectroscopy</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2252"><strong>Job details can be found here</strong></a></li></ul><h5><strong>5. Shimadzu: Field Service Engineer (GC, GCMS, TOC)</strong></h5><ul><li>Huntsville (AL), USA</li><li>Service engineer, LC, GC, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2246"><strong>Job details can be found here</strong></a></li></ul><h5><strong>6. Agilent Technologies: Field Service Engineer - GC/GCMS</strong></h5><ul><li>Remote (MN), USA</li><li>Service engineer, GC, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2219"><strong>Job details can be found here</strong></a></li></ul><h5><strong>7. Agilent Technologies: Product Specialist - Mass Spectrometry</strong></h5><ul><li>Remote, USA</li><li>Product Specialist, GC-MS, LC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2210"><strong>Job details can be found here</strong></a></li></ul><h4>🌍 <strong>Europe</strong></h4><h5><strong>8. Agilent Technologies: Product Specialist - GC GCMS</strong></h5><ul><li>Basel, Switzerland</li><li>Product Specialist, GC, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2216"><strong>Job details can be found here</strong></a></li></ul><h5><strong>9. Thermo Fisher Scientific: Field Service Engineer</strong></h5><ul><li>Oslo, Norway</li><li>Service engineer, LC, LC-MS, GC, GC-MS, AAS, ICP/OES, ICP/MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2177"><strong>Job details can be found here</strong></a></li></ul><h5><strong>10. Thermo Fisher Scientific: Technical Sales Specialist, GC/GC-MS</strong></h5><ul><li>Remote, Germany</li><li>Sales Representative, GC, GC-MS, Product Specialist</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2066"><strong>Job details can be found here</strong></a></li></ul><h5><strong>11. Thermo Fisher Scientific: Field Service Engineer For LC/GC/MS</strong></h5><ul><li>Bratislava, Slovakia</li><li>Service engineer, GC, GC-MS, LC, LC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/968"><strong>Job details can be found here</strong></a></li></ul><h5><strong>12. J. Heyrovsky Institute: Postdoctoral Researcher in Gas Phase Ion Chemistry</strong></h5><ul><li>Prague, Czech Republic</li><li>Academic staff, Analytical chemist, LC-MS, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/1893"><strong>Job details can be found here</strong></a></li></ul><h4>🌏<strong> Asia &amp; Australia</strong></h4><h5><strong>13. Agilent Technologies: Field Service Engineer</strong></h5><ul><li>New Delhi, India</li><li>Service engineer, GC, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2212"><strong>Job details can be found here</strong></a></li></ul><h5><strong>14. Thermo Fisher Scientific: Account Manager, Chrom &amp; MS</strong></h5><ul><li>Daejeon, South Korea</li><li>Sales Representative, GC, GC-MS, LC, LC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2176"><strong>Job details can be found here</strong></a></li></ul><h5><strong>15. Thermo Fisher Scientific: Sales Development Manager (Semicon &amp; Battery)</strong></h5><ul><li>Seoul, South Korea</li><li>Sales Representative, GC, GC-MS, LC, LC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2170"><strong>Job details can be found here</strong></a></li></ul><h5><strong>16. Thermo Fisher Scientific: Sales Manager - Mass Spectrometry</strong></h5><ul><li>Remote, Australia</li><li>Sales Representative, LC-MS, GC-MS, AAS, ICP/OES, ICP/MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/2175"><strong>Job details can be found here</strong></a></li></ul><h5><strong>17. Eurofins: Senior Chemist (GCMS, LCMS)</strong></h5><ul><li>Mumbai, India</li><li>Analytical chemist, GC-MS, LC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/710"><strong>Job details can be found here</strong></a></li></ul><h4><strong>Canada</strong></h4><h5><strong>18. Eurofins: GC-MS/MS Specialist</strong></h5><ul><li>Toronto (ON), Canada</li><li>Analytical chemist, GC, GC-MS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/713"><strong>Job details can be found here</strong></a></li></ul><h5><strong>19. Eurofins: GC Analyst</strong></h5><ul><li>Toronto (ON), Canada</li><li>Analytical chemist, GC, GC-MS, LC, LC-MS, UV-Vis, RAMAN, FTIR</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/job/712"><strong>Job details can be found here</strong></a></li></ul>

Global GC-MS Careers: 19 Job Offers in Gas Chromatography-Mass Spectrometry

<p><strong>Agavins, recently characterized fructans, can be rapidly detected using FT-MIR, while GC-MS offers valuable structural information. This study integrated data from both techniques to characterize agavins metabolism in </strong><i><strong>Agave angustifolia</strong></i><strong> and </strong><i><strong>Agave potatorum</strong></i><strong>. FT-MIR efficiently revealed species and age differences, while GC-MS glycosidic linkage analysis proved highly effective for multivariate data analysis.</strong></p><p>Correlation of specific MIR spectral regions with GC-MS structural features enhanced the structural detail obtainable from IR data. This integrated approach offers a faster, more comprehensive method for studying agavins metabolism and could accelerate research on these unique fructans.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c01074"><strong>Potential of FT-MIR/GC-MS Multivariate Hyphenation for the Fast Characterization of Agavins Metabolism</strong></a></h4><p>Luis F. Salomé-Abarca, Ruth E. Márquez-López, Patricia A. Santiago-García, Mercedes G. López*</p><p>Anal. Chem. 2025, XXXX, XXX, XXX-XXX</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acs.analchem.5c01074">https://doi.org/10.1021/acs.analchem.5c01074</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p><strong>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.</strong></p><p>Fructans are polymers made of fructose, if any, with one glucose in their structures. <a href="javascript:void(0);">(1)</a> Fructans are classified as linear inulins (β2→1) and levan (β2→6) with terminal glucose; neo-series of inulins and levan with internal glucose; moderate branched graminans (β2→1/β2→6); and agavins, highly branched neo-fructans. <a href="javascript:void(0);">(2,3)</a> Agavins are of great interest because of their metabolic effects and correlation with tequila production. <a href="javascript:void(0);">(4−6)</a> Thus, several studies have been conducted on the metabolism of agavins including their biosynthesis, accumulation, applications, and content in agave derived-products. <a href="javascript:void(0);">(7−10)</a> To perform such characterizations, several analytical platforms have been employed, for instance, thin layer chromatography (TLC), high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC), matrix assisted laser desorption ionization mass spectrometry (MALDI-MS), Fourier transform mid infrared spectrometry (FT-MIR), gas chromatography coupled to mass spectrometry (GC-MS), high performance anion exchange chromatography coupled to pulsed amperometric detection (HPAEC-PAD), and nuclear magnetic resonance (NMR). <a href="javascript:void(0);">(9−15)</a></p><p>Each of these techniques possesses advantages and drawbacks. Some examples include the parallel analysis of samples by TLC, but low reproducibility when manually performed. Even the implementation of HPTLC cannot properly separate agavins with a degree of polymerization (DP) higher than 12. <a href="javascript:void(0);">(16)</a> HPLC provides total inulin content data, but it cannot separate agavins with DP higher than four. <a href="javascript:void(0);">(13)</a> Conversely, HPAEC-PAD separates fructans with DP up to 40 units, but it does not provide specific structural data, is time-consuming, and needs standard compounds for identification and quantitation. <a href="javascript:void(0);">(10)</a> Proton NMR (<sup>1</sup>H NMR) is limited to overlapped fructose signals and general DP information obtained by integrating all fructose signals in respect to the glucose anomeric proton. <a href="javascript:void(0);">(2,9,15)</a> On the other hand, carbon and bidimensional experiments provide more valuable structural information, but they are time-consuming. <a href="javascript:void(0);">(2,9,15)</a> GC-MS yields structural and molar contribution data; however, samples need complex and time-consuming derivatization, and the resulting structures depend on the predominant type of fructan in the extracts. <a href="javascript:void(0);">(2,14)</a> Finally, FT-MIR possesses the fastest time of analysis, but its structural information is limited to functional groups. <a href="javascript:void(0);">(17)</a></p><p>Each analytical platform offers a specific time and space view of these molecules. Nonetheless, the study of metabolites and biomolecules tends to become more efficient and more informative. This has been achieved by the creation of new technology or the on- and offline hyphenation of multiple analytical platforms. <a href="javascript:void(0);">(16)</a> In this regard, FT-MIR gathers the fast analysis character of a high throughput approach, and GC-MS provides specific structural data based on glycosidic linkage analysis. <a href="javascript:void(0);">(2)</a> Therefore, this research aimed to evaluate the efficiency of FT-MIR and GC-MS data for the characterization of agavin metabolism and assess the feasibility of their offline hyphenation through multivariate data analysis (MVDA). Finally, we characterize the effect of the type of agavins present in the extracts on the molecular structure prediction and MVDA output. To carry out such a task, we used a previously characterized sample set of fructans extracted from the emblematic <i>Agave potatorum</i> Zucc. and <i>Agave angustifolia</i> Haw. as the model. <a href="javascript:void(0);">(18)</a></p><h4><strong>Materials and Methods</strong></h4><h5><strong>Fourier-Transformed Infrared (FT-IR) Spectroscopy</strong></h5><p>Infrared analysis was performed on a <strong>Nicolet 6700 FTIR</strong> spectrometer (Thermo Scientific) with a single bounce Smart ITR diamond ATR-accessory and a DTGS KBr detector. The IR measurements were recorded by placing 50 mg of each sample on an ATR crystal plate. For all samples (<i>n</i> = 108), 32 scans were performed between 4000 and 650 cm<sup>–1</sup> with nominal resolution of 4 cm<sup>–1</sup> in transmittance mode (%T). The MIR spectra were analyzed with OMNIC software V. 8.3.103 (Thermo Fisher Scientific Inc.). Data were used for spectra interpretation and MVDA. The spectral analysis lasted 4 h and MDVA around 2 days.</p><h5><strong>Glycosidic Linkage Analysis by GC-MS</strong></h5><p>The analysis was performed in a gas chromatograph <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7890B"><strong>7890B </strong></a>(Agilent Technologies) equipped with an automatic liquid sampler 7386B and a selective mass detector 5779A (Agilent Technologies). The separation occurred in an HP5-MS capillary column (30 m × 0.250 mm × 0.25 μm). All conditions were programed as previously described for analysis of fructan samples. <a href="javascript:void(0);">(10)</a></p><h4><strong>Results and Discussion</strong></h4><p>The GC-MS data were further scrutinized by OPLS modeling for the correlation between structural variation, age, Tfru, and °Bx. The best models for age correlation were produced by aFOS in both agave species (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S8A,B</a>). The models’ <i>Q</i><sup>2</sup> values were 0.97 and 0.98, and <i>p</i>-values of 0.02 and 0.001, respectively for <i>A. potatorum</i> and <i>A. angustifolia</i>. For Tfru correlations, the best models were also produced by aFOS (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S8C,D</a>) with <i>Q</i><sup>2</sup> values of 0.97 and 0.99, and <i>p</i>-values of 0.02 and 0.0006, respectively for <i>A. potatorum</i> and <i>A. angustifolia</i>. Among the °Bx models, the CF data produced the best one for <i>A. potatorum</i> (<i>Q</i><sup>2</sup> = 0.96, <i>p</i> = 0.00004) (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S8E</a>). For <i>A. angustifolia</i>, the best model was produced by aFOS (<i>Q</i><sup>2</sup> = 0.91, <i>p</i> = 0.02) (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S8F</a>).</p><p>Additionally, the VIP-pred-plot determined that the length of inulin chain, branching degree, number of terminal fructose, and levan ramifications are the most correlated structural features of agavins with age increase in <i>A. potatorum</i> (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S9A</a>). This represented an increase in the agavin DP and their complexity. In the case of <i>A. angustifolia</i>, all previous features, except for inulin chain length, were the most correlated structural features with age. Furthermore, <i>A. angustifolia</i> showed a correlation between age and the content of terminal glucose (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S9B</a>). This indicated that agavins in this species could possess shorter inulin chains than those of <i>A. potatorum</i> but higher branching frequency and longer levan branches along with a higher activity of sucrose:fructan 6-fructosyltransferase (6-SFT; EC 2.4.1.10). The correlation between terminal glucose and age indicated an important variation in the graminan:agavin ratio, favoring agavins, as the age of <i>A. angustifolia</i> increases. This implied an increase in the activity of fructan:fructan 6G-fructosyltransferase (6G-FFT; EC 2.4.1.243), responsible for synthetizing neo-series. <a href="javascript:void(0);">(36)</a> Differently, larger inulin chains in <i>A. potatorum</i> suggested a higher activity of fructan:fructan 1-fructosyltransferase (1-FFT). This demonstrated the power of GC-MS analysis to discriminate metabolic features between agave species. Therefore, the structural classification obtained by GC-MS can serve as an alternative tool to assign different agave materials for specific industrial purposes, for instance, aFOS-rich agaves for prebiotic production and high-DP-rich agaves as food additives or encapsulant agents. <a href="javascript:void(0);">(33)</a></p><p>As expected, the same variables were correlated in the same magnitude for the correlation of agavin structural variation through age and Tfru (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S9C,D</a>). Contrastingly, the VIP-pred-plot determined a different correlation order in the °Brix OPLS models. In the case of <i>A. potatorum</i>, internal and terminal glucose were the only two features not correlated to °Bx (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S9E</a>). This meant that carbohydrates other than graminans or agavins dictate the °Bx variation in <i>A. potatorum</i> through age. In <i>A. angustifolia</i>, levan moieties and internal glucose were not correlated with the increase of °Brix through agave age (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Figure S9F</a>). This suggested that carbohydrates determining °Brix differences through age possess similar levan branch lengths, and the ratio between graminans and agavins might affect the increase of °Brix in this species. Thus, considering FT-MIR and GC-MS data, we can state that °Bx might be a good Tfru content predictor, however, with limited potential to differentiate fructan structural variation.</p><p>For the first time, PMAAs data have been demonstrated as a tool not only for generating fructan structures but as a valuable chemometric data set. Nonetheless, this approach is time-consuming and needs specialized technical training. Therefore, establishing correlations between GC-MS and FT-MIR data could provide more structural meaning to specific wave numbers or regions, which could be later used for IR data interpretation. To assess the potential correlation between FT-MIR and GC-MS data, OPLS models were constructed setting GC-MS data (peak areas) as “Y” variables, and FT-MIR data (wave numbers) as “X” variables. For <i>A. potatorum</i>, only aFOS data produced validated results. The models for correlating inulin chains, levan chains, and branching degree produced <i>Q</i><sup>2</sup> = 0.98, 0.96, and 0.95, respectively and <i>p</i> ≤ 0.01 (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.5c01074?ref=utm_source=pubsw&amp;utm_medium=web&amp;utm_campaign=IC004_ST0004D_T000549_OA_Microsite_LP&amp;src=IC004_ST0004D_T000549_OA_Microsite_LP#fig2">Figure 2</a>A–C). Interestingly, most of the MIR ranges correlated with those features were overlapped. The ranges included 949–950, 954–956, 995, 1024–1028, 1037–1039, 1077–1078, 1091–1095, and 1106–1107 cm<sup>–1</sup> (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acs.analchem.5c01074/suppl_file/ac5c01074_si_001.pdf">Tables S8–S10</a>). Bands around 950 cm<sup>–1</sup> have been pointed as characteristic α- and β-anomers signals of cyclic carbohydrates. <a href="javascript:void(0);">(22)</a> Transmission at 995 cm<sup>–1</sup> was attributed to coupled vibrations of a −O–C–O–C–O– system. The overlapping ranges might be explained by intrinsic correlations between those structural features. For instance, increasing of the branching points indicates a parallel increase of the inulin chain length. In addition, there will be new levan moieties at each branching point. <a href="javascript:void(0);">(2,10)</a> However, an increase in levan moieties must be interpreted, along with the number of branching points. That is, an equal increase in both features might indicate more branches with short levan chains. Conversely, a small number of branching points and a high amount of levan moieties suggest less ramifications with larger levan chains.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/10_1021_acs_analchem_5c01074_Figure_2_Correlation_analysis_between_FT_MIR_and_GC_MS_data_through_OPLS_analysis_afaabe892e.jpg" alt="10.1021/acs.analchem.5c01074: Figure 2. Correlation analysis between FT-MIR and GC-MS data through OPLS analysis. (A) OPLS analysis for the correlation between inulin moieties and FT-MIR data from aFOS of Agave potatorum. (B) OPLS analysis for the correlation between levan moieties and FT-MIR data from the aFOS of A. potatorum. (C) OPLS analysis for the correlation between the branching degree and FT-MIR data from aFOS of A. potatorum. (D) OPLS analysis for the correlation between branching degree and FT-MIR data from aFOS of Agave angustifolia. (E) OPLS analysis for the correlation between terminal glucose and FT-MIR data from aFOS of A. angustifolia." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_10_1021_acs_analchem_5c01074_Figure_2_Correlation_analysis_between_FT_MIR_and_GC_MS_data_through_OPLS_analysis_afaabe892e.jpg 135w," sizes="100vw" width="1040" height="1200"></p><h4><strong>Conclusions</strong></h4><p>FT-MIR and GC-MS are robust fingerprinting platforms for the characterization of the agave fructan metabolism. FT-MIR determined that agave species are mainly differentiated by their DP-range, especially by HDP-agavins. The lower infraspecific variability of HDP-fructans conferred on them good species-biomarker character. Differently, aFOS represents a better age differentiator in agaves. GC-MS approached by MDVA provided specific linkage variation correlated to age increase, Tfru, °Bx, agave species, and age. Such correlations dilucidated an activity increase of 6G-FFT and 6-SFT in <i>A. angustifolia</i>, and 1-FFT in <i>A. potatorum</i>. Furthermore, correlations established between FT-MIR and GC-MS data corroborated the value of combining these analytical platforms by providing a more structural meaning to MIR signals. This positioned FT-MIR a step further from a common fingerprinting tool. Nonetheless, studies including a larger number of samples must be carried out to produce more robust models. FT-MIR/GC-MS correlations are species-dependent; thus, such correlations must be created for individual agave species. Finally, these correlations proved that most of the agavin structural variation in agave species through age can be profiled by aFOS. This highlights aFOS as the most informative block for the fast fingerprinting of agavins’ metabolism.</p>

Potential of FT-MIR/GC-MS Multivariate Hyphenation for the Fast Characterization of Agavins Metabolism

<p><strong>In the week of August 11, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p class="cke-user_style-important"><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Separation Science/Wiley Science Solutions: Automate Non-Targeted LC-MS/MS and GC-MS Component Identification</strong></h5><ul><li>Th, 14.8.2025 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5360">Registration</a></li></ul><p>Streamline LC-MS and GC-MS workflows with Wiley’s KnowItAll software—automate unknown identification, search 8.5M+ spectra, and explore real-world application examples in this expert-led session.</p><h5><strong>2. Agilent Technologies: Quantitation Modeling for FTIR and Raman Measurements</strong></h5><ul><li>Th, 14.8.2025 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4927">Registration</a></li></ul><p>Learn how to develop robust models for FTIR quantitative analysis using the Cary 630 FTIR spectrometer and MicroLab FTIR software, including practical guidance and case studies.</p>

Webinars LabRulezGCMS Week 33/2025

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 11th August 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you poster by <strong>Agilent Technologies / ASMS, application note </strong>by<strong> Shimadzu </strong>and technical note by<strong> Thermo Fisher Scientific!</strong></p><h3><strong>1. Agilent Technologies / ASMS: Fully Automated Workflow for Volatile PFAS Analysis in Food Contact Materials Using GC-Triple Quadrupole</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ps_7010d_pal_autusampler_pfas_asms_2025_tp_456_en_agilent_50ffdde82b.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The analysis of per- and polyfluoroalkyl substances (PFAS) in food contact materials (FCMs) is crucial due to potential health and environmental concerns. Increased PFAS testing is needed to meet public demands and new regulations. Gas Chromatography coupled with Triple Quadrupole Mass Spectrometry (GC/TQ) offers a robust and sensitive method for detecting volatile PFAS. However, manual sample preparation could pose a bottleneck, impacting lab productivity. This study presents a robust and fully automated method using the PAL3 platform with GC/TQ for quantifying more than 30 volatile PFAS in FCMs, such as paper coffee cups. The automation approach minimizes human error, improving reliability and reproducibility for routine analysis and safety assessments of PFAS in FCMs.</p><h4><strong>Experimental</strong></h4><h5><strong>Automated Sample Preparation</strong>&nbsp;</h5><p>The integrated 120 cm <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=PAL3"><strong>PAL3</strong> <strong>Series 2 RTC autosampler</strong></a><strong>,</strong> paired with the Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7010D+GC%2FMS"><strong>7010D GC/TQ</strong></a>, facilitated a fully automated PFAS quantitation workflow using a paper cup matrix. It served as an automated liquid handling platform for preparing calibration standards, extracting samples, and injecting them into the GC/TQ system, equipped with essential tools and modules.</p><h5><strong>GCMS Instrumentation&nbsp;</strong></h5><p>The 7010D GC/TQ with HES 2.0 ion source was coupled to an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890+GC"><strong>8890 GC</strong></a> system equipped with an MMI inlet and splitless liner (p/n 5190-2293). SWARM autotune optimized the instrument settings. The Agilent 8890 GC, operated in pulsed splitless mode with a splitless inlet liner, was used for analysis. The PAL3-GC/TQ system, managed by <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=MassHunter+Acquisition+software"><strong>MassHunter Acquisition 13.0 software</strong></a>, provided an integrated single-software experience. <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=MassHunter+Optimizer"><strong>MassHunter Optimizer</strong></a> was used to obtain MRM transitions for 34 targets, along with collision energies1 . Instrument operating conditions and parameters are given in the table below</p><h4><strong>Conclusions</strong></h4><ul><li>This study demonstrated a robust, fully automated method for analyzing volatile PFAS in FCMs using the PAL3 Series 2 RTC autosampler and Agilent 7010D GC/TQ system.&nbsp;</li><li>Method detection limits (MDL), linearity, retention time (RT) precision, area precision, and QC recovery was performed to assess the workflow performance.&nbsp;</li><li>The MassHunter Optimizer simplified method development, while the HES 2.0 ion source provided exceptional sensitivity, achieving sub-ppb MDLs.&nbsp;</li><li>For all FTOHs, an LOQ of 20 μg/kg with recoveries of 65% to 135% and %RSD &lt; 10% were achieved, highlighting the high extraction efficiency, accuracy and reliability of the automated workflow.&nbsp;</li><li>Automation reduces human errors, decreases chemical usage, and enhances productivity, offering reliable trace-level volatile PFAS monitoring in FCMs for regulatory guidance.</li></ul><h3><strong>2. Shimadzu: Analysis of Benzene and Toluene by </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Brevis+GC-2050"><strong>Brevis GC-2050</strong></a><strong> Using ASTM D3606&nbsp;</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00902_en_41581fffcc.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User Benefits</strong></h4><ul><li>Quantitation of benzene and toluene in fuels based on ASTM D3606 is possible.&nbsp;</li><li>Highly accurate backflush analysis is possible by using the SMI flow device.&nbsp;</li><li>The compact design of the Brevis GC-2050 enables space-saving in the laboratory.</li></ul><p>Benzene and toluene are widely used as feedstocks for chemical products, but due to concerns about their effects on human health, the permissible concentrations of these two compounds are specified in various regulations. ASTM D3606 1) provides two quantification methods (Procedures A and B) for benzene and toluene in automotive fuels. The corresponding concentrations of benzene and toluene are 0.12-5.2 Vol% and 0.4-19.7 Vol% when using Procedure A and 0.10-5.0 Vol% and 2.0-20.0 Vol% when using Procedure B. In this Application News article, benzene and toluene were quantified by Procedure A in ASTM D3606. Satisfactory linearity of the calibration curves and reproducibility of the quantitation values could be obtained for both compounds.</p><h4><strong>System Configuration and Analysis Conditions</strong></h4><p>Table 1 shows the system configuration and analysis conditions. The compact <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Brevis+GC-2050"><strong>Brevis GC-2050,</strong></a> with a width of about 35 cm, can contribute to space-saving in the laboratory while also demonstrating high analytical performance. In procedure A, benzene and toluene are measured with a backflush system using a capillary column. Backflush has the advantage of shortening the analysis time. Fig. 1 shows a schematic diagram of the backflush system. In addition to the FID detector (FID1) connected to the Wax analytical column, a second FID detector (FID2) which is connected to the restrictor tube, is used for monitoring to determine the timing of backflushing. The gas that flows through the columns is supplied from the injection port (SPL) and digital flow controller (AUX-APC). This is connected to discs called an SMI Flow Disc and 2-DET Splitter, which are used to split the flow to the two detectors. The SMI Flow Disc is a flow device for capillary analysis, and has the features of minimal leakage, a low dead volume, a low heat capacity, and inertness. For this reason, the device has the advantages that the temperature inside the device easily follows the temperature of the column oven, and it is also possible to analyze components with high adsorptivity. Before backflushing, the SPL pressure is set high, and during the backflush operation, the gas in the pre-column is made to flow in the reverse direction (backflushed) by changing the pressures of the SPL and AUX-APC. In this experiment, the initial backflush time was set to 3.1 min to match the elution time of toluene (Fig. 2).</p><h4><strong>Conclusion</strong></h4><p>Using the Brevis GC-2050, an analysis of benzene and toluene as specified in ASTM D3606 was conducted. The analysis time could be shortened by using a backflush system. As the quantitation values of benzene and toluene were within the standard range for both reproducibility and repeatability, satisfactory results were obtained.</p><h3><strong>3. Thermo Fisher Scientific: How NeverVent technology enables consistent uptime for continued lab operation&nbsp;</strong></h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/sl_003311_gc_vacuum_probe_interlock_nevervent_food_beverage_sl003311_na_en_529ea8c8af.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>Benefit summary&nbsp;</strong></h4><ul><li>Eliminates unnecessary downtime&nbsp;</li><li>Maintains productivity&nbsp;</li><li>Simplifies maintenance&nbsp;</li><li>Enables disruption-free ionization type change&nbsp;</li><li>Increases ROI</li></ul><h4><strong>What is NeverVent technology and how does it work?&nbsp;</strong></h4><p><strong>Thermo Scientific™ NeverVent ™ technology</strong> is unique to <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products?category=5&amp;manufacturerItems=3"><strong>Thermo Fisher Scientific’s GC-MS products</strong></a>. It allows for routine maintenance, exchange of ionization mode, and direct probe work to be performed without the need to break the vacuum of the mass spectrometer:&nbsp;</p><ul><li><strong>Removing/replacing the ionization source:</strong> Utilizing the vacuum probe interlock (VPI) in combination with an isolation valve, the ionization source can be removed the from the system without venting the MS. The source can either be cleaned or replaced with a spare clean source, and samples can be run without long stabilization times which would be required if the system was vented.&nbsp;</li><li><strong>Changing ionization type: </strong>Using the VPI, the ionization source can be replaced with a different type of ionization source, for example, switching from Electron Ionization (EI) to Chemical ionization (CI) within a few minutes.&nbsp;</li><li><strong>Using direct sampling probes: </strong>The VPI also allows the use of direct probes on some NeverVent GC-MS systems. This enables direct sampling into the MS system, bypassing the GC separation, and is useful in compound characterization and when analyzing very difficult to volatilize samples like oils or metal complexes.&nbsp;</li><li><strong>Changing the GC column without venting: </strong>When performing common column maintenance like trimming, or replacing the column entirely, the V-Lock Source Plug allows the MS to be sealed off from inside the manifold. Columns can be exchanged or maintained without ever breaking vacuum.</li></ul><h4><strong>What are the benefits to NeverVent technology?&nbsp;</strong></h4><p>NeverVent technology allows a significant increase in instrument uptime. On a traditional GC-MS when performing maintenance, such as ionization source cleaning or column exchange, the MS must be vented. Venting the MS introduces air and moisture into the system. Once the maintenance is performed, the system is then pumped back down to vacuum and a stabilization period is required to ensure air and moisture are evacuated from the system. This process often takes overnight to complete and means samples cannot be run until the following day.</p><p>&nbsp;Due to the unique design of a NeverVent GC-MS system, the vacuum is maintained which means samples can be run shortly after the maintenance is performed. This could be the difference betwen running a batch of samples overnight or waiting for a system to be ready to run. Utilizing NeverVent technology eliminates unnecessary instrument downtime due to venting the systems during maintenance, thus increasing productivity. Figure 2 highlights the time savings that can be achieved with NeverVent technology.&nbsp;</p><p>For a typical GC-MS system where maintenance on the source is performed every three months, NeverVent technology can give you an extra four days of operation per year. When adding in column and ionization mode changings, the productivity gains are even more significant.</p>

News from LabRulezGCMS Library - Week 33, 2025

<p><strong>In the week of August 18, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p class="cke-user_style-important"><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Shimadzu Corporation: Faster, Smarter Analysis For FAMEs And Pesticides</strong></h5><ul><li>We, 20.8.2025 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5351">Registration</a></li></ul><p>Explore how Shimadzu’s AOC-6000 Plus and Peakintelligence AI streamline GCMS and LCMS food workflows—boosting speed, throughput, and efficiency in FAME and pesticide analysis.</p><h5><strong>2. Thermo Fisher Scientific: Chromeleon CDS connections – Exploring options for interfaces</strong></h5><ul><li>We, 20.8.2025 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5383">Registration</a></li></ul><p>Learn how to integrate Chromeleon CDS with other software to streamline workflows, boost data integrity, and enhance lab efficiency. Live Q&amp;A with Thermo Fisher experts.</p><h5><strong>3. GERSTEL: Decoding Odors - Detection and Identification</strong></h5><ul><li>Th, 21.8.2025 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5405">Registration</a></li></ul><p>Discover the GERSTEL ODP 4 and ODI software for scent detection and identification using Sensory Directed Analysis, with real-world applications and expert tips.</p><h5><strong>4. Thermo Fisher Scientific: How to process MS data in Chromeleon CDS software</strong></h5><ul><li>Th, 21.8.2025 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5362">Registration</a></li></ul><p>Join us for an insightful webinar on MS Data Processing using Thermo Scientific Chromeleon 7.3.2 software.</p><h5><strong>5. Agilent Technologies: Comprehensive Guide to GC Column Bleed: From Troubleshooting to Prevention</strong></h5><ul><li>Th, 21.8.2025 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5040">Registration</a></li></ul><p>Join us as we distinguish between abnormal and normal bleed as well share some tips and tricks to control your bleed.</p>

Webinars LabRulezGCMS Week 34/2025

<p><strong>Fired cartridge cases are common evidence at shooting crime scenes. While fingerprints are often damaged and insufficient for identification, human scent traces may remain intact even after a gun is fired.</strong></p><p>In this pilot study, a simulated crime scene was created in which a volunteer loaded a weapon before firing. The scent remaining on fired cartridge cases was analyzed and compared to reference samples from several volunteers using olfactronics and olfactorics. Results suggest that scent analysis can support investigations by linking cartridge cases to the individual who handled the ammunition.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c06231"><strong>Analysis of the Human Scent on Fired Cartridge Cases from a Simulated Crime Scene</strong></a></h4><p>Ulrika Malá*, Václav Vokálek, Pavel Vrbka, Jana Čechová, Petra Pojmanová, Oleksii Kaminskyi, Veronika Škeříková, Štěpán Urban</p><p>Anal. Chem. 2025, 97, 7, 3799–3803</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acs.analchem.4c06231">https://doi.org/10.1021/acs.analchem.4c06231</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p><strong>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.</strong></p><p>Forensic olfactronics is a new field of forensic analysis whose aim is to analyze scent samples using advanced analytical chemistry techniques. <a href="javascript:void(0);">(1−3)</a> Unlike olfactorics (the odorology method using specially trained canines), forensic olfactronics is an objective method. On the other hand, the olfactory system of a canine is still more sensitive than the best contemporary instruments of analytical chemistry usable for human scent analysis. This is why both methods should be used for these purposes in the future during criminal investigations, so they can complement each other and be a desirable chain of evidence to present before the court. Cartridge cases are often one of the traces that can appear on the crime scenes usually connected with a shooting, mainly in the cases of very serious crimes. Unfortunately, the fingerprints tend to be partially spoiled; thus, they cannot be compared with the dactyloscopy database. In a previous study, <a href="javascript:void(0);">(4)</a> it was found that the less volatile substances that seem to be more significant for the individual identification of human scent <a href="javascript:void(0);">(5)</a> resist high temperatures for a short time (up to 500 °C for 1 min). That led to a presumption that at least a part of the human scent remaining on the cartridge after loading the gun and even after the gun’s firing would be sufficient for an individual identification. <a href="javascript:void(0);">(4)</a></p><h4><strong>Experimental Section</strong></h4><h5><strong>Instrumentation</strong></h5><p>For this experiment, only one gun type was used (a Sauer 38H, Sauer Sohn Germany, caliber 7.65 Browning, ammunition, type FMJ 73 grs, produced by Sellier Bellot, Czech Republic).</p><p>The samples were measured by a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7980B"><strong>7980B GC two-dimensional gas chromatograph</strong></a> (Agilent, USA) coupled with a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=24&amp;search=Pegasus+BT+4D"><strong>Pegasus BT 4D time-of-flight analyzer mass spectrometer</strong></a> (LECO, USA). The columns were connected in reverse order. The primary column was a semipolar Rtx-200MS (30 m + 2 m precolumn, Restek, USA), and the secondary column was a nonpolar <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1745"><strong>TG5-HT</strong></a> (1.1 m, Thermo Fisher Scientific, USA). The diameter of the columns was 0.25 mm, and the thickness of the stationary phase was 0.25 μm. Helium (purity 5.5, Linde CZ) was used as a carrier gas for gas chromatography. The sample was injected in a volume of 1 μL in splitless mode (2 min) at a temperature of 280 °C. The temperature gradient on the primary column started at 40 °C, held for 2 min, and ended at 320 °C, held for 10 min. The temperature increased at a rate of 5 °C/min. The temperature on the secondary column was always 5 °C higher than that on the primary column. The modulator between the two columns always had a temperature 15 °C higher than the secondary column. The cryogenic modulation at −80 °C with three modulation periods of 6, 8, and 10 s were used. The carrier gas flow rate was 1.5 mL/min. The interface between GC and MS was heated to 280 °C. The mass detector used electron ionization with an energy of 70 eV ionizing electrons, and the temperature of the ion source was 250 °C. Data collection took place in TIC (total ion current) mode, with a mass interval of 29–800 (<i>m</i>/<i>z</i>); data collection took place at a speed of 200 spectra/s. The time required to elute the solvent was set to 500 s. To increase the detection sensitivity, a 200 V higher voltage was set on the detector compared to tuning. The ratio of the signal and the noise was set at S/N 300.</p><h4><strong>Results and Discussion</strong></h4><p>By comparing the chromatograms of the scent samples collected on the original and the prewashed cartridges, significant differences supporting the necessity of the cleaning procedure before the collection itself were not found. The chromatogram area where the lubricant peaks were found was more concentrated on the original cartridges, but the differences were not significant. From a practical point of view, that is efficient for our experiments, as it gets closer to reality at the crime scene. Other experiments were carried out on nonprewashed ammunition based on these results.<named-content></named-content><named-content></named-content></p><p>Our olfactronic analysis showed successful individual separation/variance between different volunteers on the glass beads (see <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c06231#fig3">Figure 3</a>). However, the system could not link the human scent extracted from the gun-fired cartridge cases to the volunteers. This could have been caused by the different kinds of background material that was provided by glass beads (see <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c06231#fig1">Figure 1</a>) and cartridge cases (see <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acs.analchem.4c06231#fig2">Figure 2</a>), despite the fact that data editing was done in an attempt to eliminate these differences. Another option could be that even if the significant substances for the identification withstand high temperatures, the explosion heat could slightly change them. Therefore, one of the solutions could be to equalize the conditions before the extraction by heating the glass beads to the same temperature to which the bullets are exposed when fired. Nevertheless, the surface differences from which the unknown trace was collected at the crime scene do not seem to play a significant role. This is important for further investigation, as the cartridge cases remaining at the crime scene could lay on many kinds of surfaces, and the analyses of the evidence must not depend on them. The inconsistency of the result from the previous experiment <a href="javascript:void(0);">(4)</a> where the cartridge cases were successfully linked to the volunteer who had loaded the gun before the shooting could be based on the fact that another mass spectrometer (Pegasus BT-4D) with new commercial software (ChromaTOF, version 5.51.06.0) was used for this experiment. The software having issues with processing the chromatograms (mainly peak areas) may have contributed to the inconsistency.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anal_Chem_2025_97_7_3799_3803_Figure_1_Chromatogram_of_a_volunteer_s_sample_from_our_small_database_captured_on_the_glass_beads_f34c95896c.jpg" alt="Anal. Chem. 2025, 97, 7, 3799–3803: Figure 1. Chromatogram of a volunteer’s sample from our small database captured on the glass beads. The x axis represents the retention time of the first column [s], and the y axis represents the retention time of the second column [s]. The areas corresponding to individual groups of substances are indicated in the image." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anal_Chem_2025_97_7_3799_3803_Figure_1_Chromatogram_of_a_volunteer_s_sample_from_our_small_database_captured_on_the_glass_beads_f34c95896c.jpg 215w," sizes="100vw" width="2100" height="1524"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anal_Chem_2025_97_7_3799_3803_Figure_2_Chromatogram_of_an_unknown_sample_from_the_cartridge_case_736c975356.jpg" alt="Anal. Chem. 2025, 97, 7, 3799–3803: Figure 2. Chromatogram of an unknown sample from the cartridge case. The x axis represents the retention time of the first column [s]; the y axis represents the retention time of the second column [s]. The areas corresponding to individual groups of substances are indicated in the image." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anal_Chem_2025_97_7_3799_3803_Figure_2_Chromatogram_of_an_unknown_sample_from_the_cartridge_case_736c975356.jpg 207w," sizes="100vw" width="2100" height="1577"></p><h4><strong>Conclusions</strong></h4><p>Two methods for comparing four scent traces from a simulated crime scene with 22 different volunteer scent samples were used. The aim was to find a certain volunteer who loaded the gun using eight analogous cartridges. Four samples of cartridge cases were then subjected to olfactronic analysis. These were collected from a heterogeneous crime scene. These four analogous samples were also compared by trained police canines. The olfactory method was successful and correctly identified the shooter. Both methods indicated that the surface (plastic sheet, wooden palette, and concrete floor) from which the scent traces were collected does not play a significant role in the identification. The results from the forensic olfactronic method showed the ability to distinguish each volunteer sampled on the glass beads; however, it has not yet been possible to link the fired cartridge cases to any of the volunteers. In the future, this problem can be eliminated by solving the problems with processing the peaks with commercial software that comes with the two-dimensional gas chromatograph. On the other hand, the issue could also be solved by equalizing the parameters on both surfaces (cartridge cases and glass beads) by heating the glass beads after the scent is collected on them. This heating would partly simulate the process of firing the gun.</p><p>Additionally, olfactronic identification could also be complemented by a dactyloscopy comparison as well. Since both can be crucial for the investigation and together can form a desirable chain of evidence. The only question is in which order should the methods be used for the optimal analysis of both.</p><p>The future prospects for the study include expanding the research to involve more volunteers and diversifying the types of weapons and ammunition tested. Additionally, further optimization of the sample preparation process is necessary, particularly to determine whether heating the glass beads to simulate gunfire can effectively link unknown samples to the shooter. Finally, addressing the issue of data alignment will be a critical step moving forward.</p>

Analysis of the Human Scent on Fired Cartridge Cases from a Simulated Crime Scene

<p><strong>Gas chromatography (GC) is one of the most widely used analytical techniques in chemistry, pharmaceuticals, food safety, and environmental monitoring. A GC system typically consists of an autosampler, injector, columns, detectors, and a data system. Each of these modules plays a critical role in ensuring accurate, reproducible separations and quantitation.</strong></p><p>Like any complex instrument, GC systems are subject to wear and tear. Certain components are exposed to high temperatures, corrosive gases, and mechanical stress, making them more prone to failure.</p><h4><strong>Which Parts Break Down Most Often and Why?</strong></h4><ul><li><strong>Inlets (Split/Splitless, PTV, On-Column):</strong> High thermal cycling, septum punctures, and contamination from dirty samples can damage inlet bodies, liners, and seals.</li><li><strong>EPC Modules (Electronic Pneumatic Control):</strong> Precision electronics and valves regulating carrier and detector gases are sensitive to leaks, dirt, and aging, leading to flow instability.</li><li><strong>Detectors (ECD, FID, SCD, NCD):</strong> Detector assemblies rely on delicate components such as filaments, burners, or electrodes, which degrade over time.</li><li><strong>Oven Components:</strong> Fans, heaters, and exhaust deflectors can fail due to prolonged high-temperature operation.</li><li><strong>Electronic Boards and Power Supplies:</strong> Provide stable operation for all modules; aging components can lead to intermittent failures.</li></ul><h4><strong>What Needs to Be Replaced Frequently?</strong></h4><ul><li><strong>Septum and liners:</strong> Daily to weekly, depending on use.</li><li><strong>O-rings, seals, ferrules:</strong> Regular wear items, replaced as part of routine maintenance.</li><li><strong>Detector components (ECD cells, FID jets, SCD/NCD burners):</strong> Replaced when signal stability drops.</li><li><strong>EPC modules and valves:</strong> Every few years, or when gas flows become unstable.</li></ul><p>Proactive replacement of these consumable and wear parts prevents downtime and ensures your GC delivers consistent results.</p><h3><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=366"><strong>Offered GC Spare Parts</strong></a></h3><h5><strong>1.&nbsp;Agilent: Quartz Heater Burner XCD, G3488-60203 (Tested)</strong></h5><p>Quartz heater burner for Agilent 8355/8255 xCD detectors. Provides stable high-temperature combustion for accurate sulfur and nitrogen detection in GC chemiluminescence analysis.</p><ul><li><strong>Price:</strong> €1,900.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/483">Detailed offer can be found here</a></li></ul><h5><strong>2. Agilent: ECD EPC Manifold for GC 7890, G3433-60533 (Tested)</strong></h5><p>EPC manifold ensures precise gas flow to the ECD for stable and sensitive halogen compound analysis. OEM part for optimal performance.</p><ul><li><strong>Price:</strong> €2,250.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/481">Detailed offer can be found here</a></li></ul><h5><strong>3. Agilent: GC 6890 EPC Flow Control Module, G1531-69720 (Tested)</strong></h5><p>EPC flow control module for Agilent 6890 GC. Ensures precise carrier gas regulation for consistent chromatographic performance. Ideal for service or system restoration.</p><ul><li><strong>Price:</strong> €1,650.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/480">Detailed offer can be found here</a></li></ul><h5><strong>4. Agilent: SSL Manifold Assembly, G3452-60852 (Tested)</strong></h5><p>Critical mechanical and pneumatic subassembly used in Agilent GC/MS systems equipped with a Split/Splitless inlet.</p><ul><li><strong>Price: </strong>€1,650.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/459">Detailed offer can be found here</a></li></ul><h5><strong>5. Agilent: SSL with EPC Assembly, 100 PSI for 8890 GC, G3547-60100 (Refurbished)</strong></h5><p>High-pressure SSL inlet with EPC for Agilent 8890 GC, supporting split/splitless modes, precise flow control, and fast heating—ideal for trace-level and routine GC applications.</p><ul><li><strong>Price:</strong> €2,900.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/433">Detailed offer can be found here</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Agilent_SSL_with_EPC_Assy_100_PSI_for_8890_GC_ab9e45f919.jpg" alt="Agilent: SSL with EPC Assembly, 100 PSI for 8890 GC, G3547-60100" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Agilent_SSL_with_EPC_Assy_100_PSI_for_8890_GC_ab9e45f919.jpg 208w," sizes="100vw" width="1600" height="1200"></p><h5><strong>6. Agilent: 8890 EPC Module, Cool On-Column, G3450-60405 (New)</strong></h5><p>EPC module designed for precise carrier gas regulation in Agilent 8890 GC systems equipped with a Cool On-Column (COC) inlet.</p><ul><li><strong>Price:</strong> €2,200.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/402">Detailed offer can be found here</a></li></ul><h5><strong>7. Agilent: GC Exhaust Deflector, G1530-80650 (New)</strong></h5><p>Exhaust deflector assembly safely redirects heated exhaust from the oven fan away from surrounding components in Agilent GC systems.</p><ul><li><strong>Price: </strong>€250.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/400">Detailed offer can be found here</a></li></ul><h5><strong>8. Agilent: Split/Splitless Inlet Module incl. EPC for GC 7890, G3452-60800 (New)</strong></h5><p>Complete inlet with EPC module for Agilent 7890 GC, ensuring consistent and accurate sample injection.</p><ul><li><strong>Price: </strong>€2,600.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/394">Detailed offer can be found here</a></li></ul><h5><strong>9. Agilent: DPS-B Digital Power Supply Board, 01050-69374 (New)</strong></h5><p>Core electronic module responsible for providing regulated power and digital control interfaces to key subsystems within Agilent GC instruments.</p><ul><li><strong>Price</strong>: €300.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/363">Detailed offer can be found here</a></li></ul><h5><strong>10. Agilent: Split/Splitless Inlet Body, G3452-64000 (New / Refurbished)</strong></h5><p>Split/Splitless inlet body including heater/sensor and insulation, designed for use with Agilent 7890 GC systems.</p><ul><li><strong>Condition:</strong> New</li><li><strong>Price: </strong>€3,400.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/358">Detailed offer can be found here</a></li><li><strong>Condition:</strong> Refurbished</li><li><strong>Price:</strong> €2,600.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/327">Detailed offer can be found here</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Agilent_Technologies_Split_Splitless_inlet_body_2_fcdc711b29.jpg" alt="Agilent: Split/Splitless Inlet Body, G3452-64000" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Agilent_Technologies_Split_Splitless_inlet_body_2_fcdc711b29.jpg 215w," sizes="100vw" width="1597" height="1161"></p><h5><strong>11. Agilent: Deactivated Sample Probe for G1888 Headspace Sampler, 2322700011 (New)</strong></h5><p>Deactivated sample probe for the G1888 headspace sampler ensuring clean transfer of volatiles with minimal adsorption for accurate GC analysis.</p><ul><li><strong>Price:</strong> €250.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/551">Detailed offer can be found here</a></li></ul><h5><strong>12. Agilent: Small Circuit Board for 7694 Headspace Sampler, 415-305-HSP (New)</strong></h5><p>Small circuit board for the 7694A headspace sampler; detects carousel position for accurate vial alignment and reliable automated handling.</p><ul><li><strong>Price:</strong> €250.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/550">Detailed offer can be found here</a></li></ul><h5><strong>13. Agilent: Sample Vial Motor Drive Belt for 7694 Headspace Sampler, 301-010-HSP (New)</strong></h5><p>Motor drive belt for the 7694A headspace sampler; ensures smooth vial handling and dependable autosampling.</p><ul><li><strong>Price:</strong> €120.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/549">Detailed offer can be found here</a></li></ul><h5><strong>14. Agilent: Temperature Controller Board for G1888A Headspace Sampler, 3411500113 (New)</strong></h5><p>Temperature controller board (replaces board #1 or #2) for stable temperature control and reliable sample heating in the G1888A.</p><ul><li><strong>Price: </strong>€350.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/548">Detailed offer can be found here</a></li></ul><h5><strong>15. Agilent: Horizontal Loader Drive Belt for 7694 Headspace Sampler, 301-007-HSP (New)</strong></h5><p>Horizontal loader drive belt for the 7694A; enables smooth vial transfer and reliable automated sample handling.</p><ul><li><strong>Price: </strong>€95.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/547">Detailed offer can be found here</a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Agilent_Horizontal_loader_drive_belt_for_7694_headspace_sampler_301_007_HSP_2_6d8335ed2c.jpg" alt="Agilent: Horizontal Loader Drive Belt for 7694 Headspace Sampler, 301-007-HSP" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Agilent_Horizontal_loader_drive_belt_for_7694_headspace_sampler_301_007_HSP_2_6d8335ed2c.jpg 208w," sizes="100vw" width="1700" height="1275"></p><h5><strong>16. Agilent: Syringe Motor Assembly for 7673 ALS, 07673-60890 (New)</strong></h5><p>Syringe motor assembly for 7673A/7673B/G1513A ALS; delivers precise syringe control for consistent automated injections.</p><ul><li><strong>Price:</strong> €215.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/546">Detailed offer can be found here</a></li></ul><h5><strong>17. Agilent: Turret Motor Assembly for 7673 ALS, G1513-60810 (New)</strong></h5><p>Turret motor assembly for 7673 ALS G1513A; ensures precise vial positioning for reliable automated injections.</p><ul><li><strong>Price:</strong> €215.00</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/545">Detailed offer can be found here</a></li></ul>

Keep Your GC Running: Essential Spare Parts for Every Lab

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 18th August 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you poster by <strong>Agilent Technologies / ASMS </strong>and application note<strong> </strong>by<strong> Shimadzu!</strong></p><h3><strong>1. Agilent Technologies / ASMS: New Pollutant Screening of Environmental Samples Using High-Resolution GC/Q-TOF and Accurate Mass Spectral Library of Emerging Environmental Pollutants&nbsp;</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ps_7250_pdcl_library_pal3_suremass_asms_2025_thp_083_en_agilent_3f1ac53d50.pdf"><strong>Full PDF for download</strong></a></li></ul><p>This paper conducts qualitative and semi - quantitative analysis of complex GC/Q-TOF sample data by using high-resolution, accurate-mass gas chromatography/quadrupole time-of-flight mass spectrometry (GC/Q-TOF), an accurate mass spectral library of environmental pollutants specifically created for emerging pollutant screening, and analytical software with a screening process platform. Actual environmental water samples are used to verify the sensitivity, accuracy, and spiked recovery rate of the solution. All results confirm that this solution is simple, stable, and effective, providing technical support for emerging pollutant screening.</p><h4><strong>Experimental</strong></h4><h5><strong>Instrument Analysis&nbsp;</strong></h5><p>The samples were analyzed by <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890+GC"><strong>Agilent 8890 GC</strong></a> and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7250+GC%2FQ-TOF"><strong>7250 high resolution accurate mass GC/Q-TOF system</strong></a>, It was configurated with a mid-column backflush setup (Figure 1). A 55.5 - min retention time locked GC oven temperature program is utilized which is listed in Table 1. The key mass spectrometry parameters of the GC/Q-TOF are as follows: It operates in the Electron Ionization (EI) mode with an energy of 70 electron volts, conducts detection in the time-of-flight scan mode within a mass-to-charge ratio range of 50 - 1000. The spectral acquisition rate is 5 Hz, and both the interface temperature and the source temperature are set at 280 °C. Data analysis is performed with the assistance of MassHunter data analysis software. The high-resolution accurate mass spectral library employed in the screening process is independently created by the laboratory.</p><h5><strong>Data Analysis&nbsp;</strong></h5><ul><li>The data processing used Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=Masshunter+software"><strong>Masshunter data analysis software</strong></a>, including Suremass.&nbsp;</li><li>The target screening of new pollutants was based on an independently created by the laboratory GC/Q-TOF PCDL library<sup>1</sup>.</li></ul><h4><strong>Conclusions&nbsp;</strong></h4><ul><li>Based on the currently collected list of new pollutants, a truly meaningful new pollutant PCDL high-resolution spectral library has been created.&nbsp;</li><li>This work demonstrated a total workflow for targeted screening and semi-quantification in real water sample.&nbsp;</li><li>The confidence in identification of new pollutants was enhanced by stable RT and excellent mass accuracy as a result of using an RTL backflush method and highresolution accurate mass measurement.</li></ul><h3><strong>2. Shimadzu: Analysis of SAF Using Comprehensive Two- Dimensional Gas Chromatography (GC× GC)&nbsp;</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00862_en_f1ee0a435f.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User Benefits</strong></h4><ul><li>By comparing chromatograms obtained as two-dimensional images, it can be utilized for quality control Inspection of SAF.</li><li>Changing the column combination customizes separation characteristics to the sample composition.</li><li>Utilizing the FASST (Fast Automated Scan/SIM Type) allows for the simultaneous analysis of the composition of SAF and the quantitative analysis of antioxidants.</li></ul><p>SAF (Sustainable Aviation Fuel) produced from waste cooking oil, used paper, and sugarcane has gained attention in recent years from the perspective of achieving a carbon neutral society. The physical properties of SAF,such as combustibility, vary depending on its components. Therefore, component analysis of SAF is crucial; however, since SAF is a mixture of various hydrocarbons, complete separation of each component is extremely challenging. Comprehensive two-dimensional gas chromatography (GC×GC), which utilizes the separation characteristics of two different types of columns, is an effective method for analyzing SAF with such a complex composition. Additionally, the GCMS-QP2050 enables ultra-fast scanning (30,000 u/sec), which improves the separation of adjacent peaks and allows for high-precision qualitative analysis(Application News No.01-00788-EN).</p><p>In this application, two types of SAF (A and B) and one intermediate product from the SAF production process (C) were measured using a combination of GC×GC with a non-polar column as the first column and a medium-polarity column as the second column. The two-dimensional images allow for a visual representation of the composition distribution, making quality control Inspection. Moreover, high separation of paraffins and naphthenes using a combination of a medium-polar column as the first column and a non-polar column asthe second column, as well as the quantification of antioxidants in SAF, which are regulated by concentration in ASTM D2425 will be introduced.</p><h5><strong>System Configuration</strong></h5><ul><li><strong>GC Model</strong>: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Nexis%E2%84%A2+GC-2030"><strong>Nexis GC-2030</strong></a> / <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=AOC-30i"><strong>AOC-30i</strong></a></li><li><strong>MS Model</strong>: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-QP2050"><strong>GCMS-QP2050</strong></a> (TMP exhaust: 255 L/sec)</li><li><strong>Injection Port</strong>: SPL</li><li><strong>Modulator: </strong>ZX1 thermal modulator (ZOEX corp.)</li><li><strong>Nitrogen generator: </strong>MT-24F (System Instruments Co., Ltd.)</li><li><strong>Software</strong>:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Labsolutions+GCMS"><strong>Labsolutions<sup>TM</sup> GCMS</strong></a></li><li>GC Image (GC Image, LLC)</li></ul></li><li><strong>Library: </strong>NIST Mass Spectral Library</li></ul><h4><strong>Conclusion</strong></h4><p>Three SAF samples were measured using a combination of lowpolar to medium polar columns and compared the twodimensional images. The two-dimensional images allow for intuitive comprehension of the distribution of each component, making it easy to identify differences in composition and conducting quality control Inspection. Additionally, in the measurement of SAF using a combination of medium-polar to non-polar columns, the separation of paraffins and naphthenes was improved. Furthermore, by utilizing the FASST, composition analysis of SAF and quantitative analysis of antioxidants were simultaneously performed, which are regulated by concentration in ASTM D2425.</p>

News from LabRulezGCMS Library - Week 34, 2025

<p><strong>In the week of August 25, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><h4><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 500 GC, LC, MS and spectroscopy webinars</strong>.</h4></blockquote><h5><strong>1. GERSTEL: Uncovering the Cause – Identifying Off-Odors with Sensory Directed Analysis</strong></h5><ul><li>Tu, 26.8.2025 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5406">Registration</a></li></ul><p>Learn how Sensory Directed Analysis (SDA) pinpoints trace off-odors in complex samples using GC-MS, human nose, and advanced extraction techniques.</p><h5><strong>2. Separation Science: Green Chemistry in Forensic and Clinical Toxicology: HF-LPME in Action</strong></h5><ul><li>Tu, 26.8.2025 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5352">Registration</a></li></ul><p>Learn how HF-LPME aligns with green chemistry by reducing solvent use, enabling miniaturization, and simplifying workflows—shown through real-world toxicology and NPS case studies.</p><h5><strong>3. Restek Corporation: Clean + Fast: Improve Productivity for Pesticides Analysis with Resprep FL + CarboPrep Plus SPE</strong></h5><ul><li>Tu, 26.8.2025 19:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5415">Registration</a></li></ul><p>Learn how dual-bed Resprep FL+CPP SPE cartridges improve cleanup of soil and water extracts, extend column life, reduce maintenance, and deliver more reliable pesticide data.</p><h5><strong>4. Agilent Technologies: How Critical is Spectral Range to Identification of Microplastics?</strong></h5><ul><li>Tu, 26.8.2025 21:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5046">Registration</a></li></ul><p>Learn about the impact of narrowing the IR spectral range from 4,000–650 cm⁻¹ to 1,800–975 cm⁻¹ on the identification of microplastics using three different IR microscopic techniques.</p><h5><strong>5. GERSTEL: From Aroma to Insights – Identifying Key Sensory-Active Compounds</strong></h5><ul><li>We, 27.8.2025 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5407">Registration</a></li></ul><p>Explore how SDA with GC-MS and the human nose uncovers key aroma compounds in bourbon and perfume, enhanced by ADA, NIF, and advanced GC techniques.</p><h5><strong>6. LECO: Explore Complex Environmental Samples for PFAS-Related Compounds Using HR-TOFMS and Spectral Analysis Software Tools</strong></h5><ul><li>We, 27.8.2025 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5388">Registration</a></li></ul><p>Discover advanced methods for detecting PFAS in household dust and complex environmental samples using HR-TOFMS and spectral analysis software.</p><h5><strong>7. MDPI: Advancements in Analysis of Biomarkers via Gas Chromatography</strong></h5><ul><li>Th, 28.8.2025 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5416">Registration</a></li></ul><p>Join MDPI Separations’ free webinar on chromatographic biomarker analysis. Hear experts discuss GC innovations, VOC profiling, and breath biomarkers shaping medicine and health.</p><h5><strong>8. Agilent Technologies: Simplified Measurement of Content Distribution of Pharma Tablets</strong></h5><ul><li>Th, 28.8.2025 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/3905">Registration</a></li></ul><p>In this session, imaging of pharmaceutical ingredients in tablets will be discussed.</p>

Webinars LabRulezGCMS Week 35/2025

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