Analytical Challenges and Strategies for Compound Identification Using Gas Chromatography–Ion Mobility Spectrometry

<p><strong>Measurement results are only fit for purpose if the measurement uncertainty (MU) is reliable and has a magnitude small enough for the intended use. The target MU is the maximum admissible uncertainty defined for a specific measurement goal.&nbsp;</strong></p><p>In compliance assessment, the MU should be small enough to enable identification of deviations from compliance relevant to the interests to be protected (such as public health or industrial productivity). Too large an uncertainty would not provide the required protection, while an uncertainty that is too small could mean the use of unnecessary expensive measurements.&nbsp;</p><p>The Eurachem/CITAC guide on ‘<i><strong>Setting and Using Target Uncertainty in Chemical Measurement</strong></i>’ suggests how to set upper boundaries for the uncertainty based on the intended use of the result [1].&nbsp;</p><p><strong>The impact of the MU on decisions is illustrated in a fictional scenario.&nbsp;</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Setting_Target_Measurement_Uncertainty_2_daf2cb4ec8.jpg" alt="Eurachem: Setting Target Measurement Uncertainty" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Setting_Target_Measurement_Uncertainty_2_daf2cb4ec8.jpg 150w," sizes="100vw" width="740" height="770"></p><p>Mr. Reis is a farmer planning to sell oranges to a juice producer. The juice producer checks oranges for thiabendazole pesticide residues and Brix level (degrees Brix provides a measure of orange juice sweetness). The producer only accepts oranges with thiabendazole residues below 1 mg kg<sup>-1</sup> and a Brix level above 55 °Bx, paying more if the Brix level is above 65 °Bx.&nbsp;</p><p>Mr. Reis contracted Laboratory C to analyse his oranges before shipping them to the producer knowing that the customer also checks the oranges in its laboratory. Mr. Reis was very happy with the results provided by Laboratory C although the pesticide residue analyses were expensive.&nbsp;</p><p>The producer accepted the oranges but decided to pay less than expected.&nbsp;</p><p>After asking the juice producer, the detailed results of both laboratories were compared. This showed that although the results were metrologically compatible they supported different decisions on the oranges’ price.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Setting_Target_Measurement_Uncertainty_3_aa7c28e61a.jpg" alt="Eurachem: Setting Target Measurement Uncertainty - Laboratory C" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Setting_Target_Measurement_Uncertainty_3_aa7c28e61a.jpg 245w," sizes="100vw" width="927" height="192"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Setting_Target_Measurement_Uncertainty_4_4588f40881.jpg" alt="Eurachem: Setting Target Measurement Uncertainty - Juice producers Laboratory" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Setting_Target_Measurement_Uncertainty_4_4588f40881.jpg 245w," sizes="100vw" width="911" height="195"></p><p>The measurement of thiabendazole residues performed by Laboratory C is associated with an extremely low uncertainty making measurements more expensive than necessary. However, the uncertainty associated with the determination of the Brix level is too large, making compliance decisions too uncertain.</p><p>Measurement results are only fit for the intended use if the measurement uncertainty (MU) is smaller than a maximum acceptable value (i.e. the target MU).&nbsp;</p><p>Even if the customer or the regulator does not define the target MU, the laboratory should define it to decide if the measurement is fit for the intended use. The Eurachem/CITAC guide [1] suggests the use of different indicators of the measurement quality requirement to define the target MU. Information used to define the target MU is presented from the most likely to become harmonised to the ones supported with less adequate data. The following figure presents this hierarchy of adequacy with numbers from #1 to #9.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Setting_Target_Measurement_Uncertainty_01cd73bb2c.jpg" alt="Eurachem: Setting Target Measurement Uncertainty" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Setting_Target_Measurement_Uncertainty_01cd73bb2c.jpg 245w," sizes="100vw" width="1600" height="900"></p><blockquote><p>Approaches to defining the target MU described in the Eurachem/CITAC Guide, where u<sup>tg</sup> and U<sup>tg</sup> represent the target standard and expanded uncertainties, respectively. (the numbers in the bottom of the circles identify the sections of the Guide)</p></blockquote>

Setting Target Measurement Uncertainty

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p><strong>The </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a><strong> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</strong></p><h4><strong>35th International Symposium on Chromatography</strong></h4><p>📆<strong>6. - 10. September 2026</strong></p><p>📍<strong>Prague, Czech Republic</strong></p><h3><strong>REGISTRATION</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register HERE for the ISC 2026</strong></a></p><p><strong>Late Registration until 25 August 2026</strong></p></blockquote><h3><strong>VENDOR SEMINARS</strong></h3><p>Discover the vendor seminars taking place during ISC 2026 in Prague, where leading analytical technology companies will present the latest developments in chromatography, mass spectrometry, and biopharmaceutical analysis. The programme covers stationary phase selectivity, UHPLC and ion chromatography innovations, superficially porous particle columns, virtual GC-MS method modelling, and advanced LC-MS workflows for emerging therapeutics.</p><h4><strong>Lunch seminar Avantor</strong></h4><h5><strong>Stationary Phase Selectivity: A Powerful Tool for Challenging Separations</strong></h5><ul><li>Monday, 7 September 2026&nbsp;</li><li>13:00-14:00</li><li><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://form.jotform.com/262112522534345"><strong>REGISTER HERE</strong></a></li></ul><p>Stationary phase chemistry is one of the most influential variables in chromatographic method development, providing a powerful means of controlling selectivity and achieving successful separations. While the wide range of commercially available stationary phase chemistries provides extensive opportunities to optimise selectivity, navigating these choices can be challenging, often leading to suboptimal column selection and missed opportunities to improve separation performance or speed of analysis.</p><p>This seminar will explore why stationary phase selectivity is one of the most powerful tools available to chromatographers for method development. Approaches for characterizing selectivity, including the Tanaka and Neue methodologies, will be discussed as practical tools for understanding and differentiating column chemistries. These concepts will then be used to demonstrate how stationary phase design can be rationalized and how a deeper understanding of selectivity can guide more effective column selection.</p><p>Application examples will highlight the impact of stationary phase chemistry across a range of analytes, including small molecules and peptides. The seminar will also examine how rational stationary phase selection can be incorporated into streamlined workflows for reversed-phase LC, HILIC and SFC method development.</p><p>Attendees will gain a deeper understanding of how strategic column selection can enhance resolution, reduce method development time, and enhance overall method performance. The concepts presented will provide a practical framework for scientists seeking a more structured, efficient, and knowledge-driven approach to method development.</p><blockquote><p><strong>Dr Matt James</strong></p><p>Matt James is a Senior Research Scientist at Avantor Sciences. Matt gained his PhD at University of Bristol and over the last 15 years, he has worked within the Technical Support, Applications and R&amp;D teams within Hichrom, now part of Avantor. Recent focuses have been HPLC/UHPLC method transfer and translation, the use of solid core phases, development of next generation LC stationary phases and the development of LC methods for key applications, such as the analysis of nitrosamines and PFAS by LC-MS/MS.</p></blockquote><h4><strong>Lunch seminar Shimadzu</strong></h4><h5><strong>Three New Reasons to Rethink Your Workflow</strong></h5><ul><li><strong>Dr. Gesa Schad</strong>, Shimadzu Europa GmbH</li><li><strong>Dr. Waldemar Weber</strong>, Shimadzu Europa GmbH</li><li>Monday, 7 September 2026&nbsp;</li><li>13:00-14:00</li><li><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.shimadzu.eu/forms/vendor-seminar-registartion_isc2026.html"><strong>REGISTER HERE</strong></a></li></ul><p>Join us for an engaging seminar introducing three new analytical solutions designed to help laboratories work smarter, respond faster, improve robustness, and achieve greater confidence in their results. As analytical demands continue to grow, laboratories need technologies that not only deliver strong performance, but also enhance efficiency, flexibility, and ease of operation. This seminar will highlight how the latest innovations can streamline workflows, support complex applications, and create new opportunities for productivity across the laboratory.</p><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=1&amp;search=nexera+IC"><strong>Nexera IC</strong></a><strong> – new compact ion chromatograph&nbsp;</strong></h5><ul><li>This new ion chromatography solution is designed to deliver reliable, high-sensitivity analysis for a anions and cations. With a focus on stability, ease of operation, and workflow efficiency, it helps laboratories achieve consistent results while supporting applications in environmental, food, chemical, and pharmaceutical testing.</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=1&amp;search=x4"><strong>Nexera X4</strong></a><strong> – No more compromise in UHPLC analysis</strong></h5><ul><li>This next-generation UHPLC platform is designed for laboratories that demand both ultra-high performance and robust operation, without compromise. Combining improved usability with dependable, consistent results, it helps optimize throughput, improve data quality, and simplify daily workflows across both routine and advanced analyses.</li></ul><h5><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ+RX"><strong>GCMS-TQ RX Series</strong></a><strong> – Enhanced Sensitivity and Reliability in GC-MS/MS Analysis&nbsp;</strong></h5><ul><li>Our new advanced triple quadrupole GC-MS/MS systems are engineered to provide highly sensitive, selective, and dependable analysis for complex samples. Designed to support challenging applications such as trace-level detection and regulatory testing, they enable laboratories to strengthen analytical confidence, improve reproducibility, and manage demanding workflows more effectively.</li></ul><p>Join us to explore the latest innovations and gain valuable insights into our technologies. Register today to secure your place.</p><h4><strong>Lunch seminar Advanced Materials Technology</strong></h4><h5><strong>Advantages of Superficially Porous Particle Columns for HPLC and LC-MS</strong></h5><ul><li><strong>Stephanie Schuster, Joshua McBee, Conner McHale, Peter Pellegrinelli</strong> (Advanced Materials Technology, 3521 Silverside Rd., Wilmington, DE 19810)</li><li>Tuesday, 8 September 2026&nbsp;</li><li>13:00-14:00</li><li><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://halocolumns.com/isc-2026-vendor-lunch-seminar/"><strong>REGISTER HERE</strong></a></li></ul><p><br>Superficially porous particle (SPP) columns have existed in one form or another since the late 1960s. However, the benefits of the particle with the solid silica core surrounded by the porous silica shell were not realized for small molecules until 2006 when the first sub-3-µm superficially porous particle columns were introduced. This particle technology enabled efficiencies similar to sub-2-µm fully porous particles (FPPs) without the need for ultra-high pressure capable instrumentation. As a result of the high efficiencies and lower back pressure, the columns may be run at faster flow rates to enable high throughput separations. Additionally, the SPP columns are rugged and offer long column lifetimes. This presentation will highlight comparisons between SPP columns and FPP columns for separations of pharmaceuticals, pesticides, and oligonucleotides.</p><h4><strong>Lunch seminar Restek</strong></h4><h5><strong>Virtual Chromatographic Modelling Software For Optimising Separation Of Isobaric Compounds in GC-MS Methods</strong></h5><ul><li><strong>Sebastian Prisacariu, Anna Pulte</strong></li><li>Tuesday, 8 September 2026&nbsp;</li><li>13:00-14:00</li><li><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://form.jotform.com/262112099571355"><strong>REGISTER HERE</strong></a></li></ul><p>There is a constant balance for high-throughput laboratories between method run times for large panel analyses and resolution of analytes across these panels to allow sufficient data quality. Developing such methods is often time consuming and expensive for laboratories, as dedicated resources are required to test methods iteratively. Chromatographic modelling tools are becoming increasingly popular for method setup and refinement in high-throughput laboratories looking to minimise instrument and analyst downtime. These tools traditionally offer column phase and method condition suggestions based on the separation of a list of analytes, which can then be modified to improve specific separations as necessary.</p><p>When developing gas chromatography (GC) methods, shortening cycle time often comes at the cost of compounds co-eluting, with the expectation that a mass selective detector, such as a mass spectrometer (MS) will allow resolution through ion-selective quantitation. An issue arises when the method attempts to analyse isobaric compounds, which cannot be distinguished by MS, and as a result labs must rely upon physical separation via column phase chemistry.</p><p>As GC-MS techniques continue to be adopted by laboratories, there is a need for more tools that consider mass data for analytes when optimising large panel separations. The virtual chromatographic modelling tool used in this study is built with mass spectrum data for compounds included in libraries. When operating in “MS mode”, the software identifies isobaric compounds and prioritises their separation when making recommendations regarding column phase and method conditions. For those using non-mass selective detection methods, the tool is easily toggled to “FID mode” for users interested in resolving all compounds, regardless of specific mass, allowing for flexibility in instrumentation. Results help labs save time and resources in method development and refinement by considering the instrumentation involved in the model.</p><h4><strong>Lunch seminar Thermo Fisher Scientific</strong></h4><h5><strong>ASOs, ADCs, and Other Therapeutics: Advanced Characterization with Novel Reversed-Phase Columns and Integrated LC–MS Platform</strong></h5><ul><li>Tuesday, 8 September 2026&nbsp;</li><li>13:00-14:00</li><li><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=LXJ9toqqd0ehaevremo7Zz9X1b58h7ZKmlE1n_EPKh5URFJOMFFMVlZWOEc2NUQzWUlTTVY2UEhSTy4u&amp;route=shorturl"><strong>REGISTER HERE</strong></a></li></ul><p>Biotherapeutics are becoming increasingly structurally diverse, placing greater demands on analytical platforms that can support efficient development and regulatory readiness. Reversed-phase chromatography (RPC) remains a widely adopted and adaptable technique, supporting applications that range from oligonucleotide analysis to detailed protein characterization and post-translational modification assessment.</p><p>This seminar explores the integration of a macroporous, monodisperse reversed-phase column with a next-generation bioinert LC system for the analysis of two emerging classes of biotherapeutics. Antisense oligonucleotides were examined under optimized chromatographic conditions, using a design-of-experiments strategy to evaluate how ion-pairing reagents influence both LC separation and downstream MS performance. The platform was further applied to antibody–drug conjugates, combining RPC with Orbitrap mass spectrometry to support multi-level characterization. Intact, sub-unit, and bottom-up analyses enabled drug-to-antibody ratio determination alongside detailed PTM profiling — including glycosylation, oxidation, and deamidation — under native and stress conditions. Collectively, these studies demonstrate a streamlined and adaptable workflow for comprehensive biotherapeutic characterization.</p><blockquote><p><strong>Sara Carillo, Ph.D. &nbsp;</strong>(Bioanalytical Research Lead, Characterization and Comparability Laboratory National Institute for Bioprocessing Research and Training (NIBRT), Dublin, Ireland)</p><p>Sara Carillo completed her Ph.D. in chemical sciences in 2013 at the University of Naples Federico II, where she focused on the structural characterization of polysaccharides and glycoconjugates from Gram-negative bacteria using NMR and mass spectrometry techniques. In 2015, she joined the CCL group at NIBRT, led by Prof. Jonathan Bones. She began her postdoctoral research investigating the effects of extractables and leachables from single-use bioreactors on both the CHO cell N-glycome and the monoclonal antibodies they produce. She currently serves as Bioanalytical Research Lead at NIBRT, where her work centers on developing new mass spectrometry–based analytical approaches to enable deeper and more accessible understanding of biomanufacturing processes and the structural complexity of biopharmaceuticals.</p><p><strong>Sukhdev Bangar</strong> (Senior Product Marketing Manager, Thermo Fisher Scientific, Hemel Hempstead, UK)</p><p>Sukhdev graduated from De Montfort University (UK) with a BSc. in Pharmaceutical Sciences. After which he worked in the Pharmaceutical industry at GSK &amp; Astra Zeneca performing LC &amp; LC-MS analyses. From 2005 till 2023 Sukhdev worked various roles at Waters Corporation; LC-MS applications, Pharma LC-MS Demo group leader and HPLC Product manager. In his current role at Thermo Fisher Scientific he is responsible for marketing activities for the Vanquish analytical LC’s product portfolio. In this role, he represents the voice of the customer helping shape the future of Vanquish LC systems.&nbsp;</p></blockquote>

Vendor Seminars at ISC 2026

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Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Thermo Scientific SII for Empower Software

Incorporate and operate Thermo Scientific UHPLC, HPLC, GC, and IC instruments within other vendors' software platforms with the Thermo Scientific™ SII for Empower 3 Software plug-in.

<div id="product-description"><p><strong>Incorporate and operate Thermo Scientific UHPLC, HPLC, GC, and IC instruments within other vendors' software platforms with the Thermo Scientific™ Standard Instrument Integration (SII) for Empower 3 Software plug-in. The SII for Empower 3 plug-in is based on the </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS)</strong></a><strong> and offers unique and smart features that deliver maximum ease-of-use, reliability, and performance. It also enables Thermo Scientific™ chromatography systems to be operated and controlled by </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627"><strong>Waters™ Empower™ 3 CDS software</strong></a><strong>.</strong></p></div><div><p>While <strong>Chromeleon CDS</strong> is the recommended software for control of <strong>Thermo Scientific UHPLC, HPLC, GC, and IC </strong>instruments due to its maximum ease of use, reliability, and performance, other vendors' CDS software can also incorporate and operate these instruments with the <strong>SII for Empower™ 3 Software</strong> plug-in.</p><p>The SII for Empower™ Software installs and uses portions of<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon CDS</strong></a>, such as the Services Manager, Instrument Configuration Manager, Instrument View, and Instrument Method Editor, to deliver flawless integration of Thermo Scientific LC, IC, and GC instrumentation into Empower™ 3 CDS without loss of functionality. Instrument control, data acquisition, and data processing are performed completely under Empower™ 3 Software.</p><p><strong>Configure your instruments</strong><br>Up to four instruments can be configured per Empower™ node using the standard Chromeleon Instrument Configuration Manager.</p><p><strong>Control your instruments</strong><br>SII for Empower™ Software provides a complete set of commands because they are present under native <strong>Chromeleon CDS </strong>control. For the user, this means that all the Chromeleon CDS tools and advanced features, such as preparing the next sample during an ongoing analysis, can be implemented to increase productivity and receive more data with fewer injections.</p><p><strong>SII for Empower™ controls the following systems:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=37&amp;manufacturerItems=3&amp;search=Vanquish"><strong>Thermo Scientific™ Vanquish™ HPLC and UHPLC systems</strong></a></li><li><strong>Thermo Scientific™ UltiMate™ 3000 HPLC systems</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/410"><strong>Thermo Scientific™ Dionex™ ICS-6000 HPIC™ system</strong></a></li><li><strong>Thermo Scientific™ Dionex™ ICS-5000 HPIC™ system</strong></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/408"><strong>Thermo Scientific™ Dionex™ Integrion™ HPIC™ system</strong></a></li><li><strong>Thermo Scientific™ Dionex™ Aquion™ system</strong></li><li><strong>Thermo Scientific™ TRACE™ 1300 GC systems</strong></li></ul><p>Monitoring instrument status within Empower™ can be performed using the <strong>Empower™ Control Panel. </strong>Here, an enhanced SII Instrument View is easily accessed to provide further options to control and monitor the instrument and its modules.</p><p><strong>Instrument Methods</strong><br>Setting up an instrument method is simple, intuitive, and fast due to the <strong>SII for Empower™ Instrument Method Wizard and Editor</strong>, both of which are integrated into the Instrument <strong>Method Editor of Empower™</strong>. The wizard guides the user through all modules, enabling the entry of all necessary information, while the editor allows the review and modification of all aspects of a method.</p><p><strong>Process your data</strong><br>Complete data processing takes place inside<strong> Empower™ Software</strong>, which allows you to use all functionalities as you would normally, for example, overlay of chromatograms or other channels like pressure traces. The Empower™ user experience <strong>does not change </strong>for any data processing aspect.</p></div>

Thermo Scientific SureSTART Vials and Well Plates Collection

Start your analysis with confidence using SureSTART vials, caps, well plates, and kits—offering full compatibility, quality materials, and performance across three levels.

<h4><strong>Streamlined choice. Trusted quality.</strong></h4><p><strong>Start your analysis with confidence using Thermo Scientific™ SureSTART™ vials, caps, inserts, well plates, mats, and certified kits designed to meet your analytical, regulatory, and performance requirements. With full instrument compatibility, high material quality, and consistent performance across three defined levels, the SureSTART collection offers a smarter way to choose the right sample containment solution for your workflow.</strong></p><h3><strong>Why choose SureSTART?</strong></h3><ul><li><strong>Proven reliability</strong>: Every product is manufactured and certified to meet physical specifications—no weak links in your workflow.</li><li><strong>Clear selection</strong>: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial.</li><li><strong>Universal compatibility</strong>: Designed for seamless integration with all major GC, HPLC/UHPLC, and MS autosamplers across all vendors.</li><li><strong>Certified cleanliness</strong>: Products are manufactured using the purest glass and plastics with low extractables and leachables, including GOLD-grade and silanized glass.</li><li><strong>Maximum sample integrity</strong>: Minimize analyte loss and background peaks with precision-engineered sealing, surface chemistry, and material composition.</li><li><strong>Bulk savings &amp; simplified inventory</strong>: Available in multiple pack sizes, performance levels, and formats to support your lab’s needs and budget.</li></ul><h3><strong>The Three Performance Levels</strong></h3><ul><li><strong>Level 1 – Everyday analysis</strong>: For general-purpose GC/HPLC detection (e.g. UV/Vis, FID, RI). These chromatography-approved products are ideal for routine analyses with cost-efficiency in mind.</li><li><strong>Level 2 – High-throughput analysis</strong>: Designed for regulated labs requiring robust and reproducible data, especially when using MS detectors for routine quantification.</li><li><strong>Level 3 – High performance</strong>: For the most sensitive and selective analyses near the method detection limit. Packed in cleanroom environments and made with ultra-pure materials for maximum sample security and MS compatibility.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Three performance levels help you balance sensitivity, robustness, and cost, now visually marked with one, two, or three waves on the vial." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_5a8b0da936.jpg 245w," sizes="100vw" width="1182" height="270"></p><h3><strong>SureSTART Certified Vial and Cap Kits</strong></h3><ul><li><strong>Specification Certified</strong>: Routine analyses – Certified for physical specifications; no individual certificate.</li><li><strong>LC/GC Certified</strong>: Chromatography-grade – Tested for 15 physical parameters with LC-UV &amp; GC-FID; certificate included.</li><li><strong>MSCERT</strong>: For LC-MS/GC-MS – Certified low-adsorption kits tested with MS; includes SureStop™ vials with AVCS™ caps.</li><li><strong>MSCERT+</strong>: For trace-level MS or DIA – Pre-cleaned, tested with LC-MS/GC-MS, and sold only as kits to ensure purity.</li><li><strong>Application Certified</strong>: Pre-matched kits for specific instruments or validated applications.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: There are several factors to consider when choosing a vial or well plate for your application. The table below will help guide you through this process to determine what type of product/performance level is most suitable for your application requirements." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_2_fef6049d71.jpg 204w," sizes="100vw" width="1515" height="1159"></p><h3><strong>SureSTART Well Plates and Mats</strong></h3><p>Thermo Scientific™ WebSeal™ well plates are ideal for laboratories seeking to increase autosampler capacity, reduce solvent usage, and streamline high-throughput workflows. Available in <strong>96- and 384-well formats</strong>, they offer a certified alternative to traditional vials and are fully compatible with automated SPE/SLE platforms.</p><ul><li><strong>Space-saving efficiency</strong>: Replace vials with well plates to increase sample capacity up to 8× and reduce storage footprint.</li><li><strong>Flexible performance levels</strong>:<ul><li><strong>Level 1: Standard plates for routine</strong>, non-regulated use (GC-tested).</li><li><strong>Level 2: Low-bleed plates and high-performance mats</strong>, validated for LC-MS/GC-MS.</li><li><strong>Level 3: Premium WebSeal Plate+</strong> with glass-coated plastic wells—ideal for trace analytes and protein adsorption control.</li></ul></li><li><strong>Solvent stability and clean sample contact</strong>: WebSeal Plate+ uses nanolayered silicon dioxide for minimal extractables and ultra-low adsorption.</li><li><strong>Compatible sealing options</strong>:<ul><li><strong>Silicone mats: </strong>For long-term storage and consistent results.</li><li><strong>Pre-slit mats: </strong>For autosampler injection without evaporation or contamination.</li><li><strong>Adhesive seals: </strong>For single-use workflows and re-sealing options with cavity protection.</li></ul></li></ul><p>Whether you work with polar solvents, proteins, or trace-level analyses, SureSTART well plates and sealing accessories help you optimize throughput, precision, and data confidence across all chromatography workflows.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg" alt="Thermo Scientific SureSTART Vials and Well Plates Collection: Selecting the perfect Thermo Scientific WebSeal well plates and mats for your chromatography requirements is easy using our selector tools and resources." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Sure_START_Vials_and_Well_Plates_Collection_3_abce3dd960.jpg 245w," sizes="100vw" width="1516" height="902"></p>

VUV Analytics VGA-100 Gas Chromatography Detector for TRACE 1600 Series GC

The VGA-100 GC detector with VUV technology and TRACE 1600 GC delivers rapid, accurate analysis of isomers and complex mixtures with higher productivity and reliability.

<p><strong>The Thermo Scientific™ VGA-100™ Gas Chromatography Detector (developed by VUV Analytics, Inc.) introduces the next generation of GC detection through revolutionary vacuum ultraviolet (VUV) absorption technology. Delivering unmatched sensitivity, selectivity, and precision, the VGA-100 provides both qualitative and quantitative data with exceptional accuracy.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_2_e45d1cf5c3.jpg" alt="Thermo Scientific VGA-100 Gas Chromatography Detector." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_2_e45d1cf5c3.jpg 165w," sizes="100vw" width="752" height="710"></p><h3><strong>Key Benefits</strong></h3><ul><li><strong>Seamless integration with TRACE 1600 Series GC</strong> – Together, the VGA-100 and<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/483"><strong> TRACE™ 1600 GC </strong></a>form a powerful, scalable, and intuitive system designed to meet the most demanding laboratory workflows.</li><li><strong>Enhanced productivity and speed</strong> – Faster analysis, higher throughput, and reduced operational costs thanks to automated spectral deconvolution and streamlined data processing.</li><li><strong>Superior selectivity and clarity</strong> – Compound-specific absorption spectra enable confident identification of isomers and co-eluting compounds without baseline separation.</li><li><strong>Universal and mass-sensitive detection</strong> – Provides comprehensive 3D data (time, wavelength, intensity) with library matching for reliable compound identification across a broad range of analytes.</li><li><strong>Ease of use</strong> – No vacuum pumps required, minimal maintenance, intuitive operation, and full compatibility with both R&amp;D and QC environments.</li><li><strong>VUV Analyze™ Software integration</strong> – Push-button workflows, automated Time Internal Deconvolution™ (TID), and ready-to-use spectral libraries deliver fast, reliable, and reproducible results.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_5_e387eb9360.jpg" alt="Thermo Scientific VGA-100 Gas Chromatography Detector: VUV spectra of hydrocarbons exhibit class-based similarities, simplifying complex fuel mixture analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_5_e387eb9360.jpg 245w," sizes="100vw" width="1170" height="552"></p><h3><strong>Applications</strong></h3><p>The VGA-100 detector addresses critical analytical challenges such as accurate isomer identification, analyte co-elution, long run times, and complex data interpretation. It is especially impactful in:</p><ul><li><strong>Petrochemical analysis</strong> – Simplifies PIONA (paraffins, isoparaffins, olefins, naphthenes, aromatics) characterization in finished fuels, enabling rapid, automated fuel analysis.</li><li><strong>Environmental, food, and pharmaceutical testing</strong> – Reliable quantification of complex mixtures with improved accuracy and reduced calibration complexity.</li><li><strong>Quality control and research labs</strong> – Scalable, intuitive platform supporting compliance, throughput, and robust data integrity.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_3_ddcbe84bde.jpg" alt="Thermo Scientific VGA-100 Gas Chromatography Detector: Simplified PIONA compound analysis in finished gasoline." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_3_ddcbe84bde.jpg 245w," sizes="100vw" width="956" height="426"></p><h3><strong>Summary</strong></h3><p>The <strong>VGA-100 GC Detector</strong> sets a new benchmark in gas chromatography by combining VUV absorption technology with the robust performance of the TRACE 1600 Series GC. Laboratories gain a powerful “ready-to-use” solution that enhances throughput, accuracy, and confidence across diverse industries.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_4_5595ee9da1.jpg" alt="Thermo Scientific VGA-100 Gas Chromatography Detector." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_VGA_100_Gas_Chromatography_Detector_4_5595ee9da1.jpg 139w," sizes="100vw" width="816" height="918"></p>

VUV Analytics VUV Detector for TRACE 1600 Series GC

Thermo Scientific VGA-100 and LUMA VUV detectors for TRACE 1600 GC deliver accurate hydrocarbon speciation, impurity detection, and trace-level analysis with speed and reliability.

<div><div><div><div><div><h4><strong>Precision, clarity, and confidence from VUV spectroscopy in GC</strong></h4></div></div><div><div><p>VUV detectors paired with the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/483"><strong>Thermo Scientific TRACE 1600 Series GC </strong></a>conquer the challenge of complex mixtures, co-eluting compounds, and isomer differentiation&nbsp;for accurate hydrocarbon speciation, impurity detection, and trace-level detection.</p><p>Gas Chromatography (GC) is evolving, and VUV (Vacuum Ultraviolet) technology is at the forefront of this transformation. Now available on the TRACE 1600 Series GC, VUV spectroscopy, through VUV <strong>Analytics VGA-100 </strong>detector and the<strong> LUMA detector</strong>, provides accuracy in hydrocarbon speciation, impurity detection, and trace-level analysis.</p><h5><strong>Greater accuracy, automation, and confidence in your GC analysis</strong></h5><p>Traditional GC detectors struggle with complex mixtures, co-eluting compounds, and isomer differentiation. VUV spectroscopy overcomes these limitations by using absorption-based detection, capturing unique molecular fingerprints for each compound.</p><div><h3><strong>How VUV technology works</strong></h3></div><div><div><div><div><div><p>VUV detection provides qualitative and quantitative spectral information for most gas phase compounds.&nbsp;</p></div></div></div></div><div><div><div><div><div><p><strong>Broad-spectrum absorption:&nbsp;</strong>VUV detectors measure how molecules absorb light in the vacuum ultraviolet range (120–240 nm), revealing unique spectral signatures.</p><p><strong>Automated compound ID:&nbsp;</strong>To reduce errors and improve analysis speed, VUV software automatically deconvolutes overlapping peaks. unlike traditional GC detectors.</p><p><strong>Quantitative and qualitative insights:&nbsp;</strong>VUV enables compound identification and quantification in a single run by analyzing complete spectral data.</p></div></div></div></div></div><div><div><div><div><h4><strong>Principle of operations</strong></h4><div><div><div><div><ol><li><b style="font-size:1.0pc;"><strong>Sample injection in the GC: </strong></b>A sample is injected into the GC system and separated into its components as it travels through the GC column.</li><li><strong>Elution from the analytical column:&nbsp;</strong>The separated components elute from the GC column and enter the VUV detector.</li><li><strong>VUV light source:&nbsp;</strong>A deuterium lamp as VUV light source emits light in the vacuum ultraviolet range (typically 120-200 nm).</li><li><strong>Flow cell:&nbsp;</strong>The eluted components pass through a flow cell where they are exposed to the VUV light.</li><li><strong>Analytes absorption of VUV light:&nbsp;</strong>As components pass through the flow cell, they absorb VUV light at specific wavelengths. Each compound has a unique absorption spectrum in the VUV range.</li><li><strong>Analytes detection:&nbsp;</strong>Photodiode array detector measures the intensity of the transmitted VUV light. The decrease in light intensity corresponds to the absorption by the analytes.</li><li><strong>Data processing:&nbsp;</strong>Detector sends the signal to a data processing system, which converts the absorption data into a chromatogram.</li></ol><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_VUV_Detector_for_TRACE_1600_Series_GC_e3f5a229d6.jpg" alt="Thermo Scientific  VUV Detector for TRACE 1600 Series GC." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_VUV_Detector_for_TRACE_1600_Series_GC_e3f5a229d6.jpg 245w," sizes="100vw" width="2048" height="1128"></p><div><div><div><h3><strong>VUV for petrochemical and refining</strong></h3><ul><li><strong>PIONA analysis: </strong>Accurately classify paraffins, isomers, olefins, naphthenes, and aromatics with automated deconvolution for fast, confident hydrocarbon speciation and group type analysis in complex fuels.</li><li><strong>Fuel quality control (ASTM D8071):</strong> Ensure compliant, efficient fuel characterization using VUV’s spectral fingerprints, delivering fast, automated analysis for gasoline and other fuel blends.</li><li><strong>Sulfur &amp; nitrogen speciation:</strong> Detect and speciate sulfur and nitrogen compounds at trace levels in fuels, ensuring regulatory compliance and protecting product quality.</li></ul></div></div></div><div><div><div><h3><strong>VUV for pharmaceutical and chemicals</strong></h3><ul><li><strong>Residual solvent analysis: </strong>Faster, more sensitive detection of residual solvents, ensuring compliance with USP &lt;467&gt; and reducing reanalysis with precise, automated detection.</li><li><strong>Impurity profiling in APIs: </strong>VUV absorbance provides greater selectivity and lower detection limits than traditional GC detectors, ensuring reliable impurity profiling in even the most complex APIs.</li><li><strong>Trace-level contamination detection: </strong>Identify unknown contaminants at low levels in pharmaceuticals, chemicals, and environmental samples with enhanced selectivity and sensitivity.</li></ul></div><div><div><div><div><div><h4><strong>Benefits of upgrading to GC-VUV</strong></h4><div><div><div><div><div><p><strong>Hydrocarbon speciation</strong></p><ul><li>Distinguish paraffins, olefins, naphthenes, and aromatics (PONA) effortlessly</li><li>Eliminate misidentification errors common with FID and MS</li><li>Automate peak integration and classification</li></ul><div><div><div><div><div><p><strong>Trace impurity detection</strong></p><ul><li>Detect sulfur, nitrogen, and oxygen compounds at trace levels</li><li>Ensure compliance with regulatory standards in fuels and pharmaceuticals</li><li>Identify unknown contaminants in a single run</li></ul><div><div><div><div><div><p><strong>Analysis and workload</strong></p><ul><li>Decrease complex calibration standards requirement</li><li>Automated spectral deconvolution = less manual processing</li><li>Improved lab efficiency and throughput</li></ul><div><h3><strong>Which detector is right for you?</strong></h3><p>VGA-100 and LUMA detectors integrate seamlessly with the TRACE 1600 Series GC, offering plug-and-play installation, intuitive software, and superior analytical performance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_VUV_Detector_for_TRACE_1600_Series_GC_2_f6a599c167.jpg" alt="Thermo Scientific  VUV Detector for TRACE 1600 Series GC." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_VUV_Detector_for_TRACE_1600_Series_GC_2_f6a599c167.jpg 245w," sizes="100vw" width="777" height="258"></p><blockquote><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2177"><strong>VGA-100 detector</strong></a></li><li><strong>LUMA detector</strong></li></ul></blockquote></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>

Thermo Scientific Triton Series Multicollector Thermal Ionization Mass Spectrometer (TIMS)

High-precision multicollector TIMS for demanding isotope ratio analysis, delivering exceptional sensitivity, stability, and accuracy for ultra-small and low-abundance samples.

<p><strong>The Thermo Scientific™ Triton™ Series Multicollector Thermal Ionization Mass Spectrometer (TIMS) is a high-precision platform designed for the most demanding isotope ratio measurements. Built on more than two decades of continuous development, the Triton Series combines field-proven TIMS performance with state-of-the-art detection and ion-optical technologies to deliver exceptional accuracy, stability, and sensitivity—especially for small samples and low-abundance isotopes.</strong></p><p>At the heart of the Triton Series is a <strong>high-stability thermal ionization source</strong>, optimized for maximum ion transmission and minimal kinetic energy spread. This ensures highly reproducible ion beams for both single- and double-filament techniques, enabling precise isotope ratio analysis across a wide range of elements and applications.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Triton_Series_Multicollector_Thermal_Ionization_Mass_Spectrometer_TIMS_2_e9fa5e958e.jpg" alt="Thermo Scientific Triton Series Multicollector Thermal Ionization Mass Spectrometer (TIMS)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Triton_Series_Multicollector_Thermal_Ionization_Mass_Spectrometer_TIMS_2_e9fa5e958e.jpg 182w," sizes="100vw" width="650" height="558"></p><h3><strong>Advanced detection and ion optics</strong></h3><p>The Triton Series integrates multiple complementary detector technologies to address diverse analytical challenges:</p><ul><li><strong>10¹³ Ω Amplifier Technology</strong> extends the lower detection limits, delivering faster response times, extremely low noise, and significantly improved internal precision for small ion beams.</li><li><strong>Retarding Potential Quadrupole (RPQ) lenses</strong> provide exceptional abundance sensitivity by suppressing scattered ions and mass tailing, enabling accurate quantification of minor isotopes even next to intense ion beams.</li><li><strong>Multi Ion Counting (MIC) packages</strong> allow simultaneous detection of the lowest-intensity ion beams using SEM and CDD ion counters, with flexible configurations tailored to nuclear, geochronological, and geochemical applications.</li><li><strong>Stable, linear SEM and CDD ion counters</strong> ensure reliable measurements for ultra-low sample amounts and rare isotopes.</li><li><strong>High-performance Faraday cups</strong> guarantee uniform response, long operational lifetime, and excellent linearity for high-precision static and dynamic measurements.</li><li><strong>Movable multicollector array</strong> supports up to nine Faraday cups with precise alignment over a wide mass range, extendable to static Ca and Li isotope measurements.</li><li><strong>Virtual amplifier technology</strong> enables cancellation of gain factor uncertainties through amplifier rotation, achieving low-ppm external reproducibility in efficient static measurement modes.</li></ul><h3><strong>Designed for the most demanding isotope ratio applications</strong></h3><p>The Triton Series is ideally suited for applications where ultimate precision and high abundance sensitivity are essential, including:</p><ul><li>Radiogenic and stable isotope geochemistry</li><li>Geochronology (U–Pb, Pb–Pb, Rb–Sr, Sm–Nd, Lu–Hf systems)</li><li>Nuclear safeguards and nuclear forensic isotope analysis</li><li>Environmental and cosmochemical research</li><li>Analysis of ultra-small sample amounts and isotopically scarce materials</li></ul><p>Available in configurations such as <strong>Triton XT</strong> and <strong>Triton Plus</strong>, tailored to different performance priorities within high-precision isotope ratio analysis, the Thermo Scientific Triton Series TIMS offers a flexible, future-proof solution that continues to set the benchmark for thermal ionization mass spectrometry.</p>

Thermo Scientific ConFlo IV Universal Continuous Flow Interface

Universal continuous flow interface for IRMS enabling automated multi-device control, higher throughput, lower costs, and stable, unattended isotope analysis.

<p><strong>Thermo Scientific™ ConFlo IV Universal Continuous Flow Interface is a versatile continuous flow interface designed to significantly expand the application range of stable isotope laboratories using isotope ratio mass spectrometry (IRMS). The ConFlo IV system enables seamless connection of multiple sample preparation devices, delivering fully automated, stable, and highly reproducible measurements.</strong></p><p>The system features <strong>intelligent management of all required reference gases, automatic sample-size recognition, precise matching of sample and reference signals, and advanced self-diagnostics</strong>. These capabilities reduce operator involvement, lower operating costs, and increase overall laboratory throughput.</p><h3><strong>Key features</strong></h3><ul><li><strong>Management of multiple devices</strong><br>Automated switching between different sample preparation units, including activation, deactivation, and reference gas changes, maximizes IRMS utilization.</li><li><strong>Continuous, unattended operation</strong><br>Application switching can occur at any time without operator intervention; preparation devices can be regenerated and reloaded while other analyses are running.</li><li><strong>Maximized performance and efficiency</strong><br>Using reference gases instead of bulk reference materials reduces operating costs by nearly 50 % while increasing sample throughput by almost 50 %.</li><li><strong>Enhanced accuracy and stability</strong><br>Automatic adjustment of reference gas pulse intensities equalizes conditions between sample and reference gases, improving precision and long-term reliability.</li><li><strong>Advanced data quality control</strong><br>Critical system parameters affecting data quality are automatically monitored across all sample sequences.</li><li><strong>Single-interface control</strong><br>All connected preparation and inlet devices are controlled through one interface, with the ability to add new samples or entirely new applications without interrupting ongoing data acquisition.</li></ul>

Thermo Scientific DELTA Q Isotope Ratio Mass Spectrometer

High-performance IRMS combining exceptional sensitivity, robust design, and intuitive Qtegra ISDS software for food authenticity, environmental, forensic, and research isotope applications.

<p><strong>The Thermo Scientific™ DELTA™ Q Isotope Ratio Mass Spectrometer (IRMS) represents a new evolutionary step in isotope ratio analysis, combining outstanding analytical performance with intuitive operation powered by </strong><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1489"><strong>Qtegra™ Intelligent Scientific Data Solution (ISDS)</strong></a><strong> software.&nbsp;</strong></p><p>The DELTA Q IRMS is designed for seamless integration with a wide range of Thermo Scientific peripherals, making it a highly flexible platform for applications such as <strong>food authenticity testing, environmental and forensic analysis, doping control, and advanced scientific research</strong>.</p><h4><strong>Outstanding sensitivity</strong></h4><ul><li>Sensitivities of up to <strong>800 molecules per CO₂ ion</strong> in dual-inlet mode and <strong>1,000 molecules per ion</strong> in continuous-flow mode.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DELTA_Q_Isotope_Ratio_Mass_Spectrometer_2_671e47510f.jpg" alt="Thermo Scientific DELTA Q Isotope Ratio Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DELTA_Q_Isotope_Ratio_Mass_Spectrometer_2_671e47510f.jpg 197w," sizes="100vw" width="650" height="517"></p><h4><strong>Versatility for diverse applications</strong></h4><ul><li>Support for up to <strong>10 collectors</strong> in multiple configurations, covering all IRMS applications up to <strong>m/z 96</strong>.</li><li><strong>Simultaneous mass range up to ±25%</strong>, enabling efficient multi-isotope measurements.</li><li>Compatibility with <strong>preconcentrators, elemental analyzers, GC interfaces, LC interfaces</strong>, and continuous-flow inlets.</li><li><strong>On-line H₂ capability</strong> for hydrogen isotope analysis.</li></ul><h4><strong>Highly robust and reliable design</strong></h4><ul><li>A <strong>monolithic analyzer</strong> with fixed alignment of all ion-optical components, including the electromagnet, ensuring exceptional long-term stability and robustness.</li><li>Integrated signal amplifiers and digitizers minimize external connections and increase reliability.</li><li>Fixed-position ion optics eliminate the need for realignment during installation or routine maintenance.</li><li>Optimized pumping strategy enables <strong>single-stage turbo pumping</strong> for all standard continuous-flow applications.</li><li>Comprehensive, automated diagnostics driven by <strong>Qtegra ISDS software</strong> support continuous performance monitoring.</li></ul><h4><strong>Compact and user-friendly design</strong></h4><ul><li>Compact footprint requiring minimal laboratory space.</li><li>Dedicated space for online peripherals on top of the instrument.</li><li>Dual inlet, µ-volume, and multiport interfaces are neatly integrated inside the system.</li><li>Continuous-flow interfaces can be fully controlled from the front panel.</li><li>All pumps are located internally, reducing noise and laboratory clutter.</li></ul><h4><strong>Qtegra™ ISDS Software</strong></h4><ul><li>Significantly increases laboratory productivity with <strong>automatic Get Ready functionality</strong>, ready-to-use templates, and built-in quality control tools.</li><li>Intelligent, optimized workflows guide users from sample to result while allowing flexible switching between system configurations.</li><li>Ensures full <strong>data integrity and traceability</strong> for raw data, metadata, and reported results.</li></ul><h4><strong>ACT label certification</strong></h4><p>The DELTA Q IRMS is certified with the <strong>ACT Environmental Impact Label</strong> from My Green Lab, providing transparent, third-party verified information on environmental impact across manufacturing, energy and water use, packaging, and end-of-life considerations—supporting sustainable laboratory procurement and reduced carbon footprint.</p>

Thermo Scientific Prima PRO Process Mass Spectrometer

Thermo Scientific™ Prima PRO is a highly reliable process analyzer designed for fast, precise multi-stream analysis in industrial processes. It delivers high analytical accuracy, stability, and robust performance in demanding process control applications.

<p><strong>The Thermo Scientific™ Prima PRO Process Mass Spectrometer is a highly reliable and versatile gas analyzer designed for fast, precise, multi-stream gas analysis in industrial process environments. Utilizing scanning magnetic sector technology, the system delivers superior analytical accuracy, long calibration intervals, and strong resistance to contamination. These capabilities make it suitable for demanding process control applications across the chemical, petrochemical, biotechnology, semiconductor, and steel industries.</strong></p><p>The integrated Rapid Multi-Stream Sampler (RMS) inlet system enables selection from up to <strong>127 process streams</strong>, allowing a single analyzer to replace multiple gas chromatographs while maintaining high sampling frequency. The intuitive touchscreen interface, configurable user permissions, and flexible model configurations support efficient operation, regulatory compliance, and scalable deployment across diverse industrial workflows.</p><h4><strong>Key features</strong></h4><ul><li><strong>High-precision scanning magnetic sector technology</strong> for real-time gas analysis</li><li><strong>Rapid Multi-Stream Sampling (RMS)</strong> system for up to 127 process streams</li><li><strong>Programmable analytical methods</strong> with universal detector capability</li><li><strong>Optional Variable Pressure Inlet</strong> (1000 mbar to 0.3 mbar) for flexible integration</li><li><strong>Intuitive touchscreen interface</strong> with real-time data visualization</li><li><strong>Advanced security </strong>with multi-role user permissions</li><li><strong>Scalable configurations</strong> for diverse industrial applications</li></ul><h4><strong>Technical specifications</strong></h4><ul><li><strong>Analysis time: </strong>0.3–1.0 s per gas component</li><li><strong>Analyzer type: </strong>Scanning laminated electromagnet, 6 cm radius, 80° deflection</li><li><strong>Area classification:</strong> ATEX / IECEx / UKEx Zone 1 and Zone 2 T3</li><li><strong>Detector: </strong>Faraday and optional Faraday/SEM dual detector</li><li><strong>Dynamic range: </strong>1 ppm – 100% (application dependent)</li><li><strong>Power: </strong>115/230 VAC</li><li><strong>Precision: </strong>Better than 0.1% relative over 24 h</li><li><strong>Resolution: </strong>Switchable collector slits; standard resolving powers 60 (1 mm) and 20 (4 mm); optional higher resolutions</li><li><strong>Stability:</strong> Better than 10% relative over one month</li><li><strong>User interface:&nbsp;</strong><ul style="list-style-type:circle;"><li><strong>Prima PRO 710:&nbsp;</strong>Color touchscreen GUI</li><li><strong>Prima PRO 700:&nbsp;</strong>None (remote operation)</li></ul></li><li><strong>Ambient temperature:</strong> 12–42 °C</li><li><strong>Mass range:</strong> 1–200 amu</li></ul>

Thermo Scientific ITEX Dynamic Headspace Tool 

Thermo Scientific ITEX Dynamic Headspace Tool enables automated VOC enrichment with ppt sensitivity using dynamic headspace for GC workflows.

<p><strong>The Thermo Scientific™ ITEX Dynamic Headspace Tool is an autosampler accessory for the</strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/63"><strong> TriPlus™ RSH </strong></a><strong>and </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/422"><strong>TriPlus RSH SMART</strong></a><strong> Autosamplers designed for the enrichment of volatile organic compounds (VOCs) using dynamic headspace technology. It enables ppt-level sensitivity and allows sample enrichment to be easily integrated into an automated gas chromatography (GC) workflow.</strong></p><ul><li>The ITEX-DHS technique uses a gas-tight syringe to collect the headspace and a microtrap inside the syringe needle to efficiently trap and concentrate VOCs through repeated syringe strokes.&nbsp;</li><li>Sensitivity can be scaled according to the number of strokes, making the method suitable for both low- and high-concentration samples.&nbsp;</li><li>The system is designed for easy method set-up with only a few parameters, simple access to the trap, and excellent robustness for long-term operation.&nbsp;</li><li>A closed system removes any risk of breakthrough.&nbsp;</li><li>Independent trap desorption temperature and flow control maximize desorption efficiency without affecting GC inlet settings.&nbsp;</li><li>When used with the TriPlus RSH SMART autosampler, the SMART gas-tight syringe enables automatic usage traceability.&nbsp;</li><li>The entire automated workflow can be fully controlled through <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76"><strong>Thermo Scientific™ Chromeleon™ CDS</strong></a>.</li></ul><p>For VOC analysis in many liquid and solid samples, ITEX offers a valuable alternative to classical enrichment techniques by combining ease of use with robust performance.</p><h3><strong>Key features</strong></h3><ul><li>Dynamic headspace VOC enrichment with<strong> ppt-level sensitivity</strong></li><li><strong>Easy integration</strong> into automated GC workflows</li><li><strong>Gas-tight syringe and microtrap</strong> in the needle for efficient analyte concentration</li><li><strong>Scalable sensitivity</strong> based on the number of syringe strokes</li><li><strong>Easy method set-up</strong> with few parameters</li><li><strong>Robust design </strong>for long-term operation</li><li><strong>Closed system</strong> minimizing the risk of breakthrough</li><li><strong>Independent desorption</strong> temperature and flow control</li><li><strong>Automatic usage</strong> traceability with SMART gas-tight syringe</li><li>Full control through <strong>Chromeleon CDS</strong></li></ul><h3><strong>Technical specifications</strong></h3><ul><li><strong>Description: </strong>includes SMART gas-tight syringe, focusing trap, built-in trap heating, cooling fan, and trap cleaning capability</li><li><strong>Application: </strong>enrichment of volatile organic compounds (VOCs)</li><li><strong>Compatible equipment: </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/63"><strong>TriPlus RSH</strong></a> and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/422"><strong>TriPlus RSH SMART </strong></a>Autosamplers</li><li><strong>Type:</strong> autosampler accessory</li><li><strong>Unit size: </strong>each</li></ul>

Thermo Scientific Orbitrap Exploris GC S Mass Spectrometer

Orbitrap Exploris GC S delivers high-resolution GC-MS analysis of dioxins, pesticides, and POPs with accurate mass, exceptional sensitivity, and automated workflows for routine and regulatory laboratories.

<p><strong>The Thermo Scientific Orbitrap Exploris GC S is a next-generation high-resolution GC-MS system designed for the analysis of dioxins, pesticides, persistent organic pollutants (POPs), and other trace contaminants. Combining Orbitrap high-resolution accurate mass (HRAM) technology with streamlined workflows, the system enables quantitative analysis, screening, and confirmation within a single acquisition while delivering exceptional sensitivity, selectivity, and robustness.</strong></p><h4><span><strong>Key Features</strong></span></h4><ul><li>Orbitrap HRAM technology for high-resolution accurate mass measurements</li><li>Full-scan data acquisition for quantitation, screening, and confirmation</li><li>Reliable low-level detection in complex environmental and food matrices</li><li>Enhanced selectivity through accurate mass and isotope pattern recognition</li><li>Mass resolving power up to 60,000 FWHM at m/z 200</li><li>Regulatory-ready identification of dioxins, pesticides, and POPs</li><li>Expanded analytical scope without system reconfiguration</li><li>Supports method consolidation across multiple compound classes</li><li>Reduced matrix interferences and false positive results</li><li>Fast deployment and simplified system operation</li><li>Automated workflows through Chromeleon™ CDS software</li><li>Standardized procedures that reduce reliance on expert operators</li><li>Compact footprint suitable for modern analytical laboratories</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Orbitrap_Exploris_GC_S_Mass_Spectrometer_4_94149e8563.jpg" alt="Thermo Scientific: Orbitrap Exploris GC S Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Orbitrap_Exploris_GC_S_Mass_Spectrometer_4_94149e8563.jpg 156w," sizes="100vw" width="650" height="650"></p><h4><span><strong>Advanced Identification Capabilities</strong></span></h4><ul><li>Accurate mass measurements</li><li>Isotope pattern matching</li><li>Retention index confirmation</li><li>Confirmation ions</li><li>Multi-point compound identification in a single analysis</li></ul><h4><span><strong>Typical Applications</strong></span></h4><ul><li>Dioxin analysis</li><li>PCB and brominated flame retardant testing</li><li>Persistent Organic Pollutants (POPs)</li><li>Pesticide residue analysis</li><li>Environmental monitoring</li><li>Food and feed safety testing</li><li>Industrial contaminant analysis</li><li>Non-targeted screening workflows</li><li>Regulatory and forensic laboratories</li></ul><h4><span><strong>Technical Specifications</strong></span></h4><ul><li><strong>Mass Analyzer: </strong>Orbitrap HRAM</li><li><strong>Mass Range: </strong>30–3000 m/z</li><li><strong>Resolving Power: </strong>Up to 60,000 FWHM at m/z 200</li><li><strong>Scan Speed: </strong>Up to 40 Hz at resolution setting 7,500 (m/z 200)</li><li><strong>Mass Accuracy</strong><ul><li>External calibration: &lt;3 ppm RMS drift over 24 hours</li><li>Internal lock-mass calibration: &lt;1 ppm RMS drift over 24 hours</li></ul></li><li><strong>Acquisition Mode: </strong>Full-scan HRAM acquisition</li><li><strong>Software</strong><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76"><strong>Chromeleon™ Chromatography Data System (CDS)</strong></a></li><li>Dioxin HRAM eWorkflow</li><li>Automated data processing and reporting</li></ul></li></ul><h4><span><strong>Laboratory Benefits</strong></span></h4><ul><li>Single platform for targeted and non-targeted analysis</li><li>Retrospective data mining capabilities</li><li>Lower method development and validation costs</li><li>Higher productivity through workflow automation</li><li>Future-proof analytical capability without additional hardware</li><li>Ready for evolving regulatory requirements and emerging contaminants</li></ul>

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