<p><strong>Interlaboratory comparisons (ILCs) have been used for more than a century and many important concepts are linked to them. This leaflet addresses the basic terminology of ILCs, why some colloquial terms can be misleading or misunderstood, and the importance of harmonisation.&nbsp;</strong></p><p>An ‘ILC’ is the <i>organisation, performance and evaluation of measurements or tests on the same or similar items by two or more laboratories in accordance with predetermined conditions</i> [1]. ILCs have a variety of overall – and detailed – objectives, the three most common [2] being:</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Let_s_call_a_PT_scheme_a_PT_scheme_3_9993b9fb0f.jpg" alt="Eurachem: Let’s call a PT scheme a PT scheme" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Let_s_call_a_PT_scheme_a_PT_scheme_3_9993b9fb0f.jpg 245w," sizes="100vw" width="1516" height="472"></p><h4><strong>Some comparisons have special names&nbsp;</strong></h4><p>The evaluation of participant (laboratory, organisation or individual) performance is typically referred to as ‘<strong>proficiency testing</strong>’ (PT) or ‘<strong>external quality assessment</strong>’ [1]. When the main objective is evaluating the performance of, for example, a candidate standard method, the ILC is often called a ‘<strong>method performance study</strong>’ or a ‘<strong>collaborative study</strong>’ [2, 3]. The former is quite clear whereas wording such as “<strong>collaborative</strong>” and “<strong>cooperative</strong>” just stresses joint effort. A project aimed at producing a new certified reference material may involve several laboratories conducting analyses on agreed properties [4]. Not surprisingly, this work is sometimes labelled as a ‘<strong>material certification study</strong>’. Special ILCs used to demonstrate measurement capabilities of National Metrology Institutes are called ‘<strong>key comparisons</strong>’, ‘<strong>supplementary comparisons</strong>’, and ‘<strong>pilot studies</strong>’ [5].&nbsp;</p><h4><strong>Some terms can be confusing&nbsp;</strong></h4><p>Other terms for ILCs, including ‘ring test’, ‘round robin’ and ‘circle analysis’, are common in the literature. They have, however, been used for different objectives and different designs and may be ambiguous or understood differently by laboratory staff. The use of these terms may, for example, imply a specific way of distributing the ILC sample. ISO/IEC 17043 uses ‘sequential scheme’, for a PT where a unique item is transferred between the participants and ‘simultaneous scheme’, in which similar items from a batch are distributed simultaneously to the participants [1].&nbsp;</p><p>Terms like ‘<strong>measurement audit</strong>’, ‘<strong>interlaboratory testing scheme</strong>’, ‘<strong>measurement comparison scheme</strong>’, ‘<strong>rapid performance evaluation scheme</strong>’ and ‘<strong>intercalibration</strong>’ may not correctly reflect the category of laboratory involved, or the type of work participants do during the ILC.&nbsp;</p><p>When in 1994 the IUPAC defined and described three major types of ‘interlaboratory studies’, the word ‘study’ was preferred to synonyms such as ‘trial’, ‘exercise’, ‘test’, ‘evaluation’ or ‘check’ [2].</p><h4><strong>Let’s try to harmonise&nbsp;</strong></h4><p>Many laboratory staff are unaware of official terms related to ILCs but recognise the acronym PT and words like ‘ring test’. Ideally, we would use a common scientific language, but harmonisation is time consuming. Terms appear and disappear and definitions change. The same term can be defined differently, even in different international standards. Lack of standards and guidelines in local languages can cause confusion and contribute to spreading of less appropriate terms.&nbsp;</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Let_s_call_a_PT_scheme_a_PT_scheme_2_820043ce8b.jpg" alt="Eurachem: Let’s call a PT scheme a PT scheme" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Let_s_call_a_PT_scheme_a_PT_scheme_2_820043ce8b.jpg 234w," sizes="100vw" width="1006" height="671"></p><p>Much confusion can be avoided by clear reference to relevant standards and sectoral guides. ISO/ IEC 17043 [1] and ISO 13528 [6] contain many important concepts related to PT schemes and other ILCs. Some of these are also incorporated into ISO/IEC 17025 [7]. Additional useful, and free, tools are the Eurachem PT Guide [8] and the ISO online browsing platform [9].&nbsp;</p><p>In writing guidance and instructions, remember that the term ‘interlaboratory comparison’ has a broad meaning and can be used for all cases described above. Sometimes this is clear enough for the reader. In other cases, use acknowledged terms that reflect the detailed objective of the ILC. Let’s call a PT scheme a PT scheme!</p>

Let’s call a PT scheme a PT scheme!

<p><span><strong>The countdown is on for one of the world’s leading conferences dedicated to food analysis. The 12th International Symposium on Recent Advances in Food Analysis (RAFA 2026), taking place in Prague from 3–6 November 2026, is approaching two important milestones: the Early Bird registration deadline and the deadline for oral abstract submissions, both ending on 30 June 2026. Researchers, analysts, industry professionals, regulators, and students are encouraged to secure their participation at a reduced registration rate and take advantage of the opportunity to present their latest scientific results to the international food analysis community.</strong></span></p><p><span>RAFA 2026 will once again bring together leading experts from academia, industry, and regulatory organizations to discuss the latest developments in food safety, authenticity, contaminants, non-target screening, PFAS, microplastics, food contact materials, artificial intelligence, and advanced analytical technologies. The preliminary program already features an outstanding lineup of internationally recognized speakers addressing some of the most pressing challenges in modern food analysis and food safety.</span></p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://rafa.easyevent.eu/tickets/"><strong>Register to attend RAFA 2026!</strong></a></p><p><strong>Early-bird registration until 30 June, 2026</strong></p></blockquote><p>After successful submission of your registration, you will receive by e-mail (i) an automatic confirmation of receipt indicating the total amount of payment due (either for bank transfer or for on-line payment by card), (ii) login to Member section where you can administrate your profile, submit your abstracts, and from <strong>September 2026</strong> register for satellite events, workshops and seminars. If it will not be delivered within a few minutes after submission of your registration please contact us at <strong>RAFA2026@vscht.cz</strong>.</p><p>As soon as payment of registration fee is processed, you will also receive by e-mail (iii) confirmation of payment.</p><h4><strong>Registration Fees</strong></h4><ul><li><strong>Smart rate (Until 30 June, 2026): </strong>€ 655</li><li><strong>Regular registration (Until 30 September, 2026):</strong> € 855</li><li><strong>Late registration (From 1 October, 2026):</strong> € 955</li><li><strong>Student rate*&nbsp;</strong><ul><li><strong>Until 30 June, 2026: </strong>€ 465</li><li><strong>From 1 July, 2026:</strong> € 605</li></ul></li></ul><p><i>* The proof of student status (e.g. copy of a student identify card) is requested as an attachment of the registration form.</i></p><h5><strong>The regular registration fee will include:</strong></h5><ul><li>Attendance at all scientific sessions, workshops, seminars, vendor seminars and other satellite events</li><li>Access to the poster and exhibition area</li><li>Conference kit (name badge, conference bag, conference documents, certificate of participation, certificate of presentation on request)</li><li>Final programme</li><li>E-Book of Abstracts</li><li>Coffee breaks</li><li>Buffet luncheons</li><li>Welcome drink</li></ul><p>In the registration form you can r<strong>egister free of charge for the welcome drink</strong> and you can also order <strong>ticket(s) for the conference dinner (€ 85).</strong></p><p><i>Please note that your registration is firm when your payment has been received.</i></p><h3><strong>Abstract submission</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://rafa.easyevent.eu/tickets/"><strong>Submit your ABSTRACT HERE!</strong></a></p><p>In order to submit an abstract, you must <strong>first register to attend RAFA 2026</strong>. <strong>After registration</strong> you will receive an <strong>access to the Member section </strong>where you can <strong>submit your abstract(s).</strong></p></blockquote><p>&nbsp;After successful submission of your abstract you will receive an automatic confirmation of receipt of submitted abstract via e-mail. If it will not be delivered within a few minutes after submission of your abstract please check at first your spam box-mail and then contact us at <strong>RAFA2026@vscht.cz</strong>.</p><p>Please ensure that your abstract does not contain spelling, grammatical or scientific errors. Even though modifications of your submitted abstract will be allowed in the Abstract section of the Member section until the deadline for the abstract submission, please be confident on the lack of errors in your final version prior to starting the submission process.</p><p>The abstract will be reproduced exactly as submitted. No proofreading will be done, although some corrections may be requested by the reviewers.</p><p>If you need to withdraw your abstract, a written statement reflecting the reasons for this decision must be sent to <strong>RAFA2026@vscht.cz</strong> no later than <strong>September 30, 2026</strong>.</p><h4><strong>Important notice:</strong></h4><blockquote><p><strong>1 registered participant can submit no more than 2 abstracts.</strong></p></blockquote><p>To apply for a young scientist’s oral presentation, as an indication please respect the rule that you should be born in 1991 or later.</p><p>The <strong>text of the abstract </strong>should be<strong> limited to 3000 characters including spaces</strong>. Tables and pictures are not allowed.</p><p><strong>Abstracts of oral presentations and posters</strong> will be included into the "<strong>e-Book of Abstracts</strong>" only after receipt of the conference registration fee. Any payment of the registration fee has to be received until <strong>September 30, 2026</strong>, otherwise contribution(s) will not be included into the e-Book of Abstracts and the Conference programme.</p><h3><strong>Program</strong></h3><h4><strong>Invited Speakers</strong></h4><h5><strong>Food allergen risk assessment: Past, present, future</strong></h5><ul><li>Ben Remington from Remington Consulting Group B.V., Utrecht, the Netherlands &amp; University of Nebraska, USA</li></ul><p>Food allergy and allergen management are global public health issues, and consumer protection depends on transparent and trustworthy labelling. While 30 years of scientific advances show that low level exposures, or reference doses, are unlikely to trigger reactions in most allergic individuals, harmonized and globally aligned regulations are still needed to promote consistent allergen risk assessment and labelling decisions. This presentation will discuss the landscape of allergen risk assessment, global policy developments, current research and future needs in the area.</p><h5><strong>Unmasking hidden adulteration in honey: Strategies for detecting and characterizing honeys produced from sugar-fed colonies</strong></h5><ul><li>Oscar Nuñez Burcio from University of Barcelona, Barcelona, Spain</li></ul><p>From hive to jar, not all honey tells the same story. This presentation addresses hidden adulteration associated with sugar-fed bee colonies, highlighting implications for authenticity, production practices, and the need for a more precise characterization of honey to ensure consumer trust.</p><h5><strong>Analytical and toxicological methods for safety of food contact materials</strong></h5><ul><li>Erich Leitner from Graz University of Technology, Institute of Analytical Chemistry and Food Chemistry, Graz, Austria</li></ul><p>Food packaging plays a critical role in protecting and preserving food throughout the supply chain. All packaging materials intended to come into contact with food must comply with strict EU safety rules. Due to increased complexity of packaging solutions, lowering legal limits and increasing numbers of target compounds, we also have to adapt the strategies used to verify and guarantee the safety of these materials.</p><h5><strong>Data-driven strategies to reduce complexity in non-target HRMS analysis of food samples</strong></h5><ul><li>Anneli Kruve from Stockholm University, Stockholm, Sweden</li></ul><p>LC/HRMS based non-target screening can detect hundreds to thousands of chemical features in complex food and environmental samples. Investigating all of these in detail is practically impossible, so which ones to focus on? Novel computational tools developed in computational mass spectrometry allow predicting the toxicity and concentration of the detected chemical features even if these have not yet been fully structurally elucidated. Combining these predictions enables us to focus on the chemical features possessing high risk.</p><h5><strong>Role of AI in the identification of emerging food systems risks</strong></h5><ul><li>Ákos Bernard Jóźwiak from Syreon Research Institute, Budapest, Hungary</li></ul><p>AI-assisted evidence synthesis – spanning curated scientific evidence, exposome data, and network analysis – is the backbone of next-generation emerging chemical food safety risk identification, enabling earlier signals and more resilient surveillance systems.</p><h5><strong>Challenges of microplastics analysis in the context of food safety</strong></h5><ul><li>Dorte Herzke from Norwegian Institute of Public Health, Oslo, Norway</li></ul><p>Food and food packaging are major sources of micro- and nanoplastic exposure. Plastics used in processing, storage, and packaging can release particles through heat, abrasion, and degradation. Small particles below 2 µm may cross gut barriers and carry chemicals, highlighting the need for robust and sensitive measurement methods.</p><h5><strong>Never-ending analytical challenges in PFAS analysis of food</strong></h5><ul><li>Darina Dvořáková from University of Chemistry and Technology Prague, Prague, Czechia</li></ul><p>Exploring and monitoring PFAS in food requires advanced strategies. Combining targeted, suspect, and non-target HRMS analysis, determination of total fluorine and sum parameters, and novel sensors provides new insights into PFAS occurrence and supports food safety monitoring.</p><h5><strong>An overview of the latest scientific knowledge on process contaminants in food for appropriate risk management measures</strong></h5><ul><li>Thierry Delatour from Nestlé Research, Lausanne, Switzerland.</li></ul><p>Recent scientific findings related to acrylamide and furans formation, occurrence and analytical methods in food provide important insights for risk management.</p>

Deadline for RAFA 2026 Early Registration and Oral Abstract Submission is approaching

<p><strong>Traditional EI library searching works exceptionally well when the unknown compound is already present in the spectral library. However, analytical chemists frequently encounter compounds that are structurally related to library entries but are not exact matches. NIST's EI Hybrid Search addresses this challenge by combining conventional spectral matching with mass-shifted fragment alignment, allowing the identification of analogs, derivatives, and novel compounds that may not exist in the database.</strong></p><p>This guide summarizes the workflow presented by James Little and demonstrates how to use NIST 26 Hybrid Search in conjunction with the Chromatogram Window and MS Interpreter to obtain more meaningful structural information from unknown EI GC-MS spectra.</p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/33370"><strong>You can download PDF Handout for this guide HERE</strong></a></p></blockquote><h4><strong>Why Hybrid Search Matters</strong></h4><p>Conventional EI library searching relies on direct matching between an unknown spectrum and spectra stored in a library. Hybrid Search expands this concept by allowing fragment ions to be matched even when they are shifted by a consistent mass difference (Δm). This enables the software to recognize compounds that differ by substituents or structural modifications.</p><p><strong>Key advantages include:</strong></p><ul><li>Identification of structurally related compounds not present in the library</li><li>Detection of analogs, derivatives, and emerging compounds</li><li>Integration of exact fragment matches and mass-shifted matches into a single score</li><li>Improved interpretation of unknowns through proposed structural modifications</li><li>Enhanced confidence when molecular weight information is available</li></ul><p>Although Hybrid Search does not require the molecular ion to be present, performance improves significantly when the molecular weight can be estimated or constrained. In these cases, the observed mass difference between the unknown and library compounds can often be translated directly into a plausible chemical modification.</p><h4><strong>Configuring Hybrid Search</strong></h4><p>Before performing a search, the Hybrid Search settings should be configured within the NIST Library Search window.</p><p>Recommended settings:</p><ul><li>Select the Similarity search mode</li><li>Enable Hybrid Search</li><li>Keep the In Spectrum option checked under normal circumstances</li><li>Allow the software to estimate the molecular weight automatically</li><li>If the estimated molecular weight appears incorrect, manually enter a nominal molecular weight</li><li>Select all relevant libraries (NIST, Wiley, user libraries, etc.)</li><li>Save the configuration for future use</li></ul><p>The selected molecular weight used to constrain the search is displayed in the lower-right corner after the search is completed.</p><h4><strong>Optimizing the Results Display</strong></h4><p>Hybrid Search produces several unique parameters that are not shown in the default results table.</p><p>Additional columns should be added by right-clicking within the results table and selecting Properties. Recommended columns include:</p><ul><li>DeltaMass</li><li>dForm</li><li>pctRelForm</li><li>o.Match (equivalent to the traditional EI Normal Match score)</li></ul><p>Without these parameters, much of the structural interpretation power of Hybrid Search is lost.</p><h4><strong>Working with Spectra from the Chromatogram Window</strong></h4><p>Currently, the Chromatogram Window performs standard EI library searching. When a potentially interesting unknown is encountered:</p><ul><li>Perform the normal EI search in the Chromatogram Window</li><li>Send the spectrum to the standalone Library Search module</li><li>Perform a Hybrid Search using the enhanced Hybrid Search functionality</li></ul><p>This workflow combines rapid screening with advanced structural interpretation.</p><h4><strong>Understanding Key Hybrid Search Parameters</strong></h4><h5><strong>DeltaMass (Δm)</strong></h5><p>DeltaMass represents the mass difference between the unknown compound and the matched library compound.</p><p>A consistent Δm across multiple high-scoring hits often indicates a specific structural modification.</p><h5><strong>dForm</strong></h5><p>dForm provides a proposed elemental composition that explains the observed mass difference.</p><p>Examples include:</p><ul><li>H–1F</li><li>CH₂</li><li>O–1</li><li>C₁H₃F</li></ul><p>These transformations can suggest likely chemical modifications between the library compound and the unknown.</p><h5><strong>pctRelForm</strong></h5><p>New in NIST 26, pctRelForm estimates how frequently a given elemental transformation occurs relative to the most common transformation (CH₂ = 100%).</p><p>Interpretation:</p><ul><li>High values indicate chemically plausible and commonly observed transformations</li><li>Very low values suggest the proposed transformation may be accidental or unlikely</li></ul><h5><strong>o.Match</strong></h5><p>Represents the traditional EI match score and allows comparison between standard searching and Hybrid Search results.</p><h4><strong>Case Study: Identifying a Fluorinated Unknown</strong></h4><p>The presentation demonstrates the identification of an unknown compound with a proposed molecular weight of 152 Da.</p><p>Hybrid Search returned several high-scoring hits with consistent evidence suggesting fluorine substitution:</p><p><strong>Hit #1</strong></p><ul><li>Library MW: 134</li><li>DeltaMass: +18</li><li>dForm: H–1F</li><li>Interpretation: Addition of fluorine</li></ul><p><strong>Hit #5</strong></p><ul><li>Library MW: 138</li><li>DeltaMass: +14</li><li>dForm: CH₂</li><li>Interpretation: Related fluorinated analog</li></ul><p><strong>Hit #6</strong></p><ul><li>Library MW: 168</li><li>DeltaMass: –16</li><li>dForm: O–1</li><li>Interpretation: Structurally consistent fluorinated compound</li></ul><p>Multiple independent hits converged on the same conclusion: the unknown was likely a fluorinated analog of known aromatic compounds.</p><p>This illustrates the major strength of Hybrid Search: identifying structural relationships even when the exact compound is absent from the library.</p><h4><strong>Moving from Hybrid Search to Structural Interpretation</strong></h4><p>Once a plausible structure is identified:</p><h5><strong>Step 1 – Export the Structure</strong></h5><p>From the Hybrid Search results:</p><ul><li>Right-click the best hit</li><li>Use Send To → Default Structure Editor</li><li>Open the structure in a drawing program such as ChemSketch</li><li>Copy the proposed structure to the clipboard</li></ul><h5><strong>Step 2 – Open MS Interpreter</strong></h5><p>Within MS Interpreter:</p><ul><li>Paste the proposed structure</li><li>Load the unknown spectrum</li><li>Compare predicted fragmentation with observed ions</li><li>Evaluate isotope patterns and fragment assignments</li></ul><h5><strong>Step 3 – Validate the Proposal</strong></h5><p>Indicators of a good structural proposal include:</p><ul><li>Consistent isotope ratios</li><li>Logical fragmentation pathways</li><li>Agreement between observed and predicted fragment ions</li><li>Multiple Hybrid Search hits supporting the same structural modification</li></ul><p>In the example presented, MS Interpreter showed excellent agreement between the proposed fluorinated structure and the observed EI spectrum, although the exact positions of the fluorine and methyl substituents on the aromatic ring could not be definitively assigned.</p><h4><strong>Best Practices</strong></h4><ul><li>Always review DeltaMass, dForm, and pctRelForm together</li><li>Do not rely solely on the highest match score</li><li>Give greater weight to transformations supported by multiple independent hits</li><li>Use molecular weight information whenever possible</li><li>Confirm structural hypotheses using MS Interpreter</li><li>Consider Hybrid Search as a structure-elucidation tool rather than simply a library search tool</li></ul><h4><strong>Conclusion</strong></h4><p>NIST 26 Hybrid Search significantly extends the capabilities of conventional EI library searching by identifying structural relationships between unknown compounds and library entries. Through the use of DeltaMass calculations, elemental transformation analysis (dForm), and statistical plausibility metrics (pctRelForm), Hybrid Search provides valuable clues for elucidating compounds that are absent from spectral libraries.</p><p>When combined with MS Interpreter, it becomes a powerful workflow for the characterization of unknowns, analogs, degradation products, metabolites, and emerging compounds in EI GC-MS analysis.</p>

Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window

Article

Events

Academy

Video

Software

RAFA provides an overview of contemporary trends in ANALYTICAL & BIOANALYTICAL STRATEGIES IN FOOD QUALITY AND SAFETY CONTROL and discusses CHALLENGES / NOVEL APPROACHES IN FOOD AND NATURAL PRODUCTS ANALYSIS.

Recent Advances in Food Analysis (RAFA)

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

LECO Multi-Mode Source

Multi-Mode Source (MMS) integrates EI, PCI, and NCI/ECNI in a single GC-MS ion source, enabling instant software-based mode switching with perfect peak alignment and enhanced unknown identification.

<p><strong>The innovative Multi-Mode Source (MMS) integrates the strengths of the three most widely used GC-MS ionization techniques—Electron Ionization (EI), Positive Chemical Ionization (PCI), and Negative Chemical Ionization (NCI/ECNI)—into a single, easy-to-use source. With MMS, switching ionization modes is software-controlled and instantaneous, eliminating hardware changes and alignment concerns.</strong></p><p>Paired with the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/38"><strong>Pegasus GC-HRT+</strong></a>, MMS delivers excellent mass accuracy and high resolution for pseudo-molecular ions, complementing traditional high-resolution EI (HR-EI) to enable comprehensive characterization of unknown compounds. Because the hardware remains untouched during mode changes, chromatographic peaks stay perfectly aligned across ionization modes—simplifying comparison and interpretation.</p><p>All three ionization modes (EI, PCI, NCI/ECNI) are available for both <strong>GC-MS</strong> and <strong>GC×GC-MS</strong> workflows on the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/39"><span><strong>Pegasus GC-HRT+ 4D</strong></span></a> as well as the Pegasus GC-HRT+ systems.</p><h3><strong>Key Benefits</strong></h3><ul><li><strong>Three ionization modes in one source</strong>: EI, PCI, and NCI/ECNI</li><li><strong>No hardware swapping or realignment</strong>: mode changes at the click of a button</li><li><strong>Consistent peak alignment</strong> across ionization modes</li><li><strong>Enhanced unknown identification</strong> via complementary EI and CI information</li><li><strong>Compatible with GC-MS and GC×GC-MS</strong> on Pegasus GC-HRT+ platforms</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Multi_Mode_Source_2_79908249a5/LECO-Multi-Mode-Source-2.jpg" alt="LECO: Multi-Mode Source for the Pegasus GC-HRT+ and Pegasus GC-HRT+ 4D" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Multi_Mode_Source_2_79908249a5/thumbnail_LECO-Multi-Mode-Source-2.jpg 245w," sizes="100vw" width="1817" height="1082"></p>

LECO PEGASUS BT 4D GC×GC-TOFMS

LECO PEGASUS BT 4D GC×GC-TOFMS combines comprehensive two-dimensional GC with fast TOFMS to improve separation, sensitivity, and confidence in qualitative and quantitative analysis of complex samples.

<p><strong>The LECO PEGASUS BT 4D GC×GC-TOFMS is a high-performance benchtop system that combines comprehensive two-dimensional gas chromatography (GC×GC) with time-of-flight mass spectrometry (TOFMS) to deliver unmatched separation power, sensitivity, and confidence in compound identification. Designed for laboratories facing highly complex samples, the PEGASUS BT 4D enables qualitative and quantitative analysis in a single run while maximizing productivity and data quality.</strong></p><p>By coupling GC×GC separation with fast TOFMS acquisition, the system <strong>dramatically increases chromatographic peak capacity and resolves co-eluting compounds </strong>that are difficult or impossible to distinguish by conventional 1D GC-MS. Enhanced signal-to-noise ratios translate into lower detection limits, improved linearity, and more reliable quantification—even in challenging matrices.</p><h3><strong>What GC×GC Brings to Your Analysis</strong></h3><p>GC×GC modulation refocuses and reinjects analytes from the first column into a second column with a different stationary phase, providing structured chromatograms that improve interpretability of complex data. This approach improves both separation efficiency and interpretability of results, allowing you to identify more compounds with greater confidence and consistency.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_c9ad0bd186.jpg" alt="LECO PEGASUS BT 4D GC×GC-TOFMS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_c9ad0bd186.jpg 245w," sizes="100vw" width="1029" height="594"></p><h3><strong>Confident Identification and Quantification</strong></h3><p>The PEGASUS BT 4D excels in both comprehensive screening and targeted applications. Spectral deconvolution combined with high-speed TOFMS acquisition reveals analytes present in complex matrices, while GC×GC separation minimizes matrix interferences for superior quantitative performance. What was once a marginal library match in GC-MS becomes a confident identification in GC×GC-TOFMS.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_2_4e033e866c.jpg" alt="LECO PEGASUS BT 4D GC×GC-TOFMS: Quantitative analysis using the Pegasus BT 4D" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_2_4e033e866c.jpg 245w," sizes="100vw" width="1443" height="637"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_3_18eebd600d.jpg" alt="LECO PEGASUS BT 4D GC×GC-TOFMS: Qualitative analysis using the Pegasus BT 4D" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_3_18eebd600d.jpg 210w," sizes="100vw" width="1442" height="1069"></p><h3><strong>Robust Design for High-Throughput Labs</strong></h3><p>Equipped with LECO’s proven StayClean® ion source, the PEGASUS BT 4D minimizes routine maintenance and downtime, even when analyzing dirty or complex samples. Integrated with <strong>ChromaTOF®</strong> software, the system provides seamless instrument control, automated data processing, and powerful qualitative and quantitative tools within a single platform.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_c2644cd38e.jpg" alt="LECO - PEGASUS BT 4D GCxGC-TOFMS.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_c2644cd38e.jpg 202w," sizes="100vw" width="1099" height="849"></p><h3><strong>Key Benefits</strong></h3><ul><li>Exceptional chromatographic resolution and peak capacity with GC×GC</li><li>Enhanced sensitivity and lower detection limits through modulation-based signal focusing</li><li>High-speed TOFMS acquisition for accurate deconvolution of narrow GC×GC peaks</li><li>Reliable identification and quantification of analytes</li><li>Reduced maintenance with the StayClean® ion source</li><li>Fully integrated ChromaTOF® software for acquisition, processing, and reporting</li></ul><h3><strong>Applications</strong></h3><p>The LECO PEGASUS BT 4D GC×GC-TOFMS is ideally suited for demanding applications across environmental analysis, petrochemical and energy research, food and flavor/fragrance analysis, forensics, life sciences, and metabolomics—anywhere complex mixtures require maximum separation power and analytical confidence.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_4_8e8ec115ec.jpg" alt="LECO PEGASUS BT 4D GCxGC-TOFMS: Excellent Sensitivity" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_4_8e8ec115ec.jpg 244w," sizes="100vw" width="974" height="625">With the PEGASUS BT 4D, you can <strong>predict, quantify, and identify more compounds with confidence</strong>, turning complex data into clear, actionable results.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_5_625fed2f0d.jpg" alt="LECO PEGASUS BT 4D GCxGC-TOFMS: Identify MORE with confidence/non-target analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PEGASUS_BT_4_D_G_Cx_GC_TOFMS_5_625fed2f0d.jpg 240w," sizes="100vw" width="1034" height="672"></p>

LECO Pegasus GC-HRT+

Ultra-high-resolution GC-TOFMS with up to 50,000 FWHM, <1 ppm mass accuracy, and 200 spectra/s. Pegasus GC-HRT+ delivers unmatched sensitivity and confident identification in complex samples.

<p><strong>Now with even higher sensitivity, the Pegasus GC-HRT+ is designed to meet the most demanding analytical challenges. This high-performance GC-TOFMS delivers industry-leading mass accuracy, full-range acquisition at exceptional speed, precise isotopic abundance, and ultra-high mass resolution—all within a single injection.</strong></p><p>Folded Flight Path (FFP) technology combined with a novel data acquisition system enables up to <strong>50,000 FWHM resolution</strong>, <strong>&lt;1 ppm mass accuracy</strong>, and <strong>acquisition rates up to 200 spectra/s</strong>, supporting rich analyte discovery and high-confidence identification in highly complex samples.</p><h3><strong>Key features</strong></h3><ul><li><strong>Mass accuracy ≤1 ppm</strong> with peak capacity at least <strong>2× higher</strong> than conventional MS platforms</li><li><strong>Encoded Frequent Pushing (EFP)</strong> for markedly increased sensitivity, expanded dynamic range, and wide mass range</li><li><strong>Folded Flight Path (FFP)</strong> technology for ultra-high resolution, enhanced sensitivity, and advanced TOF focusing</li><li><strong>KADAS®</strong> ion-statistics-based acquisition to reduce noise, ensure mass accuracy, and minimize file size</li><li><strong>Ultra High Resolution + HRD</strong> to resolve highly isobaric ions (mass differences ~0.02 amu)</li><li><strong>Multi-Mode Source (MMS):</strong> EI, Positive CI, and ECNI in one system</li></ul><h3><strong>Models</strong></h3><ul><li><strong>Pegasus GC-HRT+</strong> – Full-scale GC-TOFMS</li></ul><h3><strong>Options</strong></h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/82"><strong>L-PAL3 Automated Sample Injector</strong></a></li></ul>

LECO Pegasus GC-HRT+ 4D

High-resolution GC×GC-TOFMS system combining extreme separation power, up to 200 spectra/s acquisition, and advanced HR deconvolution for confident identification of unknowns in complex samples.

<p><strong>The Pegasus GC-HRT+ 4D from </strong><span><strong>LECO</strong></span><strong> combines comprehensive two-dimensional gas chromatography (GC×GC) with high-resolution time-of-flight mass spectrometry (TOFMS) and advanced High-Resolution Deconvolution (HRD). Designed for the most complex sample matrices, the system enables detection, separation, and confident identification of more analytes than ever before. </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/41"><strong>ChromaTOF® software</strong></a><strong>, purpose-built for HRT+ instrumentation and GC×GC workflows, integrates advanced qualitative and quantitative tools into a single, user-friendly data system.</strong></p><h3><strong>Key Features</strong></h3><ul><li><strong>Compact benchtop design</strong> that saves valuable laboratory space</li><li><strong>Industry-leading sensitivity</strong> with proprietary deconvolution algorithms for clean, high-quality spectra</li><li><strong>High acquisition speed</strong> up to 200 spectra/s to properly define ultra-narrow GC×GC peaks (&lt;200 ms)</li><li><strong>Complete historical mass-spectral record</strong> retained for future data mining and reprocessing</li><li><strong>Proven Pegasus reliability and durability</strong> in a modern, space-efficient format</li></ul><h3><strong>GC×GC Performance Explained</strong></h3><p>GC×GC achieves exceptionally high peak capacity by trapping compounds eluting from the first column and reinjecting them into a second column for rapid secondary separation. These second-dimension separations occur within seconds, producing extremely narrow peaks that demand very high spectral acquisition rates. The Pegasus GC-HRT+ 4D meets and exceeds this requirement, enabling robust spectral deconvolution and confident compound identification in highly complex samples.</p><h3><strong>Available Configurations</strong></h3><ul><li><strong>Pegasus GC-HRT+ 4D with Liquid Nitrogen Thermal Modulator</strong></li><li><strong>Pegasus GC-HRT+ 4D with Cryogen-Free Modulator</strong></li></ul><h3><strong>Optional Accessories</strong></h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/82"><strong>L-PAL3 Autosampler</strong></a></li></ul>

Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer

Achieve high scanning speeds and reproducible measurements with the Thermo Scientific™ Prima BT Bench Top Mass Spectrometer.

<div><div><p><strong>Achieve high scanning speeds and reproducible measurements with the Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer. Specifically designed for process development laboratories, this real-time process gas analyzer is a highly precise, multi-port magnetic sector analyzer.</strong></p></div><div><p>The <strong>Prima BT Process Mass Spectrometer</strong> offers robust performance in the presence of off-gases and vapors that have the potential to contaminate internal vacuum components. As the ions are extracted from the ion source at high energy, excellent stability is achieved for low molecular weight compounds such as hydrogen and helium.</p><h4><strong>✔️ Key Features</strong></h4><ul><li>Scanning magnetic-sector technology</li><li>16-port Rapid Multistream Sampler (RMS)</li><li>Six-port automatic calibration manifold</li><li>High analytical precision, accuracy and stability</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/pharma-biopharma/manufacturing-control-pharma-biopharma/process-analytical-technology/gasworks-process-analysis-software.html">Thermo Scientific™ GasWorks Software</a></li></ul><h4><strong>Warranty and Service Offering</strong></h4><p>To maintain optimal product performance, you need immediate access to experts worldwide, as well as priority status when your analyzer needs repair or replacement. We offer <strong>comprehensive, flexible support solutions </strong>for all phases of the product life cycle. Through <strong>predictable, fixed-cost pricing</strong>, our services help protect the return on investment and total cost of ownership of your Thermo Scientific products.</p></div><div><p>The <strong>Thermo Scientific Prima BT Bench top Mass Spectrometer </strong>is an industrial laboratory gas analyzer based on scanning magnetic-sector mass spectrometry. Designed for continuous operation in a laboratory environment, the Prima BT mass spectrometer is simple to operate and easy to maintain.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_1_b38b34871c/Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-1.jpg" alt="Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_1_b38b34871c/thumbnail_Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-1.jpg 199w," sizes="100vw" width="927" height="726"></p><h3><span><strong>⚙️ Specifications</strong></span></h3><ul><li><strong>Analysis Time:</strong> 0.3 to 1.0 sec. per gas component</li><li><strong>Analyzer Type:</strong> Scanning Magnetic Sector Mass Spectrometer with Enclosed Electron Impact Dual Filament Ion Source</li><li><strong>Area Classification Options:</strong> General Purpose</li><li><strong>Depth (English):</strong> 1.8 ft.</li><li><strong>Depth (Metric):</strong> 0.56 m</li><li><strong>Dynamic Range:</strong> Faraday: 10 ppm to 100 ppm</li><li><strong>Dynamic Range (optional):</strong> Single MCP SEM: 1 ppm to 1000 ppm; Twin MCP SEM: 10 ppb to 1000 ppm</li><li><strong>Height (English):</strong> 1.7 ft.</li><li><strong>Height (Metric):</strong> 0.53 m</li><li><strong>No. of Calibration Gas Inlets:</strong> Up to 6</li><li><strong>No. of Sample Stream Inlets:</strong> Up to 15</li><li><strong>Power:</strong> 115/230 V, Consumption: 1.5 kVA</li><li><strong>Precision:</strong> ≤ 0.1% relative</li><li><strong>Stability:</strong> ≤ 1% relative over one week</li><li><strong>Weight (English):</strong> 220 lb., Additional floor mounting rotary pump: 66 lb.</li><li><strong>Weight (Metric):</strong> 100 kg, Additional floor mounting rotary pump: 30 kg</li><li><strong>Width (English):</strong> 2.8 ft.</li><li><strong>Width (Metric):</strong> 0.86 m</li><li><strong>Ambient Temperature:</strong> 12 °C to 30 °C</li><li><strong>Communication Protocols:</strong> Modbus serial RS232/422/485, Siemens 3964R, VGCP and PVGCP</li><li><strong>Mass Range:</strong> Adjustable, 1 to 150 amu at 1000 eV ion acceleration voltage, 1 to 200 amu at 750 eV ion acceleration voltage</li><li><strong>Product Type:</strong> Prima BT Bench Top Process Gas Analysis Mass Spectrometer</li><li><strong>Unit Size:</strong> Each</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_2_b4a02abf9d/Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-2.jpg" alt="Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_2_b4a02abf9d/thumbnail_Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-2.jpg 166w," sizes="100vw" width="1269" height="1189"></p></div></div>

Thermo Scientific Orbitrap™ Exploris™ GC Mass Spectrometer

Transform your data quality to deliver the right answer first time, every time with the Thermo Scientific™ Orbitrap™ Exploris™ GC Mass Spectrometer.

<div><div id="product-description"><strong>Simplify operations and deliver consistently accurate results in analytical testing using the Thermo Scientific™ Orbitrap™ Exploris™ GC Mass Spectrometer. This GC-MS system offers a unique depth of analysis and unparalleled accuracy and precision to improve everyday quantitation, screening and sample profiling. It provides the flexibility to keep pace with ever-changing regulations and explore new analytical opportunities through increased scope and method consolidation. Simple instrument set up and intelligent informatics enable users of all abilities to easily access data-rich information.</strong></div><div><h4><strong>Deliver accurate quantitative results and spend less time reviewing data in high throughput analytical testing</strong></h4><ul><li>Offers the power and flexibility of full-scan high-resolution accurate mass data to quantitative, screening and discovery workflows</li><li>Accelerates data reviewing with multi-point compound identification, including spectral matching, isotope pattern match, retention indices and multiple confirmation ions</li></ul><h4><strong>Be one step ahead of changing demands</strong></h4><ul><li>Provides the flexibility to keep pace with ever-changing regulations and enables you to explore new business opportunities through increased scope and method consolidation</li><li>Offers the option to configure the system with either 30,000 or 60,000 mass resolving power and the ability to add MS/MS capability today or in the future</li></ul><h4><strong>Focus on results, not instrument setup</strong></h4><ul><li>Simple instrument set up and intelligent informatics enable users of all abilities to easily access data-rich information</li><li>Next-generation software, including built-in method templates, provides easy-to-use and flexible options that are fully accessible to all members of the analytical team</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Thermo_Scientific_Orbitrap_Exploris_GC_Mass_Spectrometer_337a570de7.jpg" alt="Thermo Fisher Scientific: Thermo Scientific Orbitrap™ Exploris™ GC Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Thermo_Scientific_Orbitrap_Exploris_GC_Mass_Spectrometer_337a570de7.jpg 245w," sizes="100vw" width="1032" height="617"></p><h4><strong>Benefits that boost productivity</strong></h4><h5><strong>Increase scope</strong></h5><p>Gain the flexibility to quickly add new compounds without compound optimization and decide post acquisition which analytes to measure.</p><h5><strong>Fast system setup</strong></h5><p>Walk up, tune, and calibrate in under five minutes with full confidence that the system is operating at maximum performance for all users.</p><h5><strong>Efficient review and reporting</strong></h5><p>Use multiple points of identification to quickly confirm or reject detections, increasing peace of mind. Spectral matching, isotope patterns, retention indices, and elemental compositions provide high confidence in results.</p><h5><strong>Accurate quantitation</strong></h5><p>Six orders of linear dynamic range covers the concentrations encountered in even the most complex sample matrices.</p><h5><strong>Method consolidation</strong></h5><p>Combine acquisition methods onto a single system, reducing the need for multiple systems and streamlining data processing.</p><h5><strong>Retrospective analysis</strong></h5><p>Interrogate previously acquired high-resolution accurate-mass (HRAM) data in multiple ways to answer additional analytical questions without additional sample injections.</p><h4><strong>Power GC-MS with Thermo Scientific software solutions</strong></h4><ul><li><strong>Chromeleon CDS:</strong> Enterprise-ready, regulatory-compliant quantitation</li><li><strong>TraceFinder software:</strong> High-throughput screening and quantitation</li><li><strong>Compound Discoverer software:</strong> Small-molecule unknown identification</li></ul><h3><strong>Specifications</strong></h3><ul><li><strong>Dynamic Range:</strong> &gt;5000 within a single Orbitrap mass analyzer spectrum</li><li><strong>Mass Range: </strong>30 to 3000 m/z</li><li><strong>Mass Accuracy: </strong>External calibration achieves &lt;3 ppm RMS drift over 24 hours, Internal lock mass calibration achieves &lt;1 ppm RMS drift over 24 hours</li><li><strong>Resolution: </strong>Up to 60,000 at m/z 200</li><li><strong>Scan Rates: </strong>Up to 40 Hz at resolution setting 7,500 at m/z 200</li><li><strong>Description:</strong> Orbitrap Exploris GC Mass Spectrometer, no MS/MS</li></ul></div></div>

Thermo Scientific™ Orbitrap™ Exploris™ GC 240 Mass Spectrometer

Take research capability to a new, unprecedented level of performance with the Thermo Scientific™ Orbitrap Exploris™ GC 240 mass spectrometer and accelerate your scientific discovery. 

<p><strong>Simplify the most complex analytical challenges and achieve excellent data quality with the Thermo Scientific™ Orbitrap™ Exploris™ GC 240 mass spectrometer.&nbsp;</strong></p><p>By delivering <strong>uncompromising qualitative and quantitative information</strong>, this <strong>high-resolution accurate-mass GC-MS system</strong> addresses the evolving requirements of research laboratories for <strong>compound identification and quantitation</strong>. From <strong>discovery profiling</strong>, <strong>metabolomics</strong> and <strong>applied quantification</strong>, scientists gain <strong>unparalleled access to information-rich data and results</strong>.</p><p><strong>Experience breakthrough performance in high resolution GC-MS analysis</strong> to gain the <strong>deepest insights</strong> into your sample.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Orbitrap_Exploris_GC_240_Mass_Spectrometer_1_99d830b929/Thermo-Orbitrap-Exploris-GC-240-Mass-Spectrometer-1.jpg" alt="Thermo Scientific™ Orbitrap™ Exploris™ GC 240 Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Orbitrap_Exploris_GC_240_Mass_Spectrometer_1_99d830b929/thumbnail_Thermo-Orbitrap-Exploris-GC-240-Mass-Spectrometer-1.jpg 156w," sizes="100vw" width="650" height="650"></p><h5><strong>The Orbitrap Exploris GC 240 mass spectrometer:</strong></h5><ul><li><strong>Enables you to get the right answer first time</strong></li><li><strong>Offers the flexibility to adapt to ever-changing needs</strong> with its <strong>superior mass accuracy, dynamic range and robustness</strong></li><li><strong>Includes intelligent instrument setup and an intuitive user experience</strong> to make it fully accessible for users of all skill levels</li><li><strong>Offers unprecedented 240,000 resolution (at m/z 200)</strong> to deliver <strong>sub-1-ppm mass accuracy</strong> and <strong>sensitivity down to part-per-trillion concentrations</strong></li><li><strong>Maintains system sensitivity at all mass resolution levels</strong>, so there is <strong>no need to compromise between resolution and sensitivity</strong></li><li><strong>Features repeatable performance injection after injection</strong> to enable discoveries to be made across <strong>high sample studies</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Orbitrap_Exploris_GC_240_Mass_Spectrometer_2_8a411289bf/Thermo-Orbitrap-Exploris-GC-240-Mass-Spectrometer-2.jpg" alt="Thermo Scientific™ Orbitrap™ Exploris™ GC 240 Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Orbitrap_Exploris_GC_240_Mass_Spectrometer_2_8a411289bf/thumbnail_Thermo-Orbitrap-Exploris-GC-240-Mass-Spectrometer-2.jpg 156w," sizes="100vw" width="650" height="650"></p><h3><strong>Thermo Scientific™ Orbitrap™ Exploris™ GC 240 Mass Spectrometer Specifications</strong></h3><ul><li><strong>Description:</strong> Orbitrap Exploris GC 240 Mass Spectrometer</li><li><strong>Dynamic Range:</strong> &gt;5000 within a single Orbitrap mass analyzer spectrum</li><li><strong>Mass Accuracy:</strong> External calibration achieves &lt;3 ppm RMS drift over 24 hours, Internal lock mass calibration achieves &lt;1 ppm RMS drift over 24 hours.</li><li><strong>Scan Rates:</strong> Up to 40 Hz at resolution setting 7,500 at m/z 200</li><li><strong>Mass Range:</strong> 30 to 3000 m/z</li><li><strong>Resolution:</strong> Up to 240,000 at m/z 200</li><li><strong>Unit Size:</strong> Each</li></ul>

Thermo Scientific ISQ™ 7610 Single Quadrupole GC-MS

Thermo Scientific ISQ™ 7610 Single Quadrupole GC-MS. Simplified operation, automated workflows, and extended dynamic range deliver consistent results from system to system in every laboratory.

<p><strong>To stay ahead, analytical testing laboratories need the ultimate confidence of a GC-MS system that easily and reliably produces trusted results, day after day. For this, you can count on the Thermo Scientific™ ISQ™ 7610 Single Quadrupole GC-MS System. Simplified operation, automated workflows, and extended dynamic range deliver consistent results from system to system in every laboratory. Thermo Scientific™ NeverVent™ technology, extended-life detector, and intelligent software eliminate unnecessary downtime to maximize sample throughput. To ensure you are ready for any analytical challenge, the system is upgradeable from entry-level to advanced configurations. Now you can take the lead with rapid return on investment (ROI) for your regulated GC-MS analyses.</strong></p><h4><strong>Unstoppable confidence in quantitative performance</strong></h4><p>Delivers femtogram-level sensitivity so you consistently meet required detection limits as you run samples, whether you run in SIM mode or Full Scan. The ISQ 7610 GC-MS features a unique ion path that neutral particles cannot navigate and a choice of an ExtractaBrite or AEI ion source, depending on your sensitivity needs. The instrument’s XLXR detector which is an electron multiplier detector has an extended lifetime and extended dynamic range. Extended dynamic range capability enables labs to combine methods allowing analysis of low- and high-concentration compounds in a single run.</p><h4><strong>The right choice for any workflow</strong></h4><p>The intuitive <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/cz/en/home/industrial/chromatography/chromatography-data-systems-cds.html">Thermo Scientific Chromeleon Chromatography Data System (CDS)</a> is available to help streamline quantitative workflows and ready-to-use Thermo Scientific eWorkflows can be downloaded from the <a target="_blank" rel="noopener noreferrer" href="https://appslab.thermofisher.com/">Thermo Scientific Appslab Library of Analytical Applications</a> to jump-start your method development. For U.S. EPA-based environmental applications, the Environmental Analysis Extension pack provides a set of GC-MS e-workflow and reporting templates.</p><h4><strong>Unstoppable instrument uptime for full-time productivity</strong></h4><p>The robust design of the ISQ 7610 GC-MS ensures that the system can work continuously to produce the highest quality results possible. High matrix tolerance minimizes routine maintenance, but when maintenance is required, the NeverVent technology available with the ExtractaBrite ion source enables source cleaning, column replacement or injector maintenance without requiring downtime to vent the instrument, so more time can be spent producing results.</p><h4><strong>Ease of use that helps you stay ahead</strong></h4><p>Automated software for instrument tuning, method development, targeted quantification and untargeted screening workflows make the ISQ 7610 GC-MS system easy to learn and enables quick transition to this system from other platforms. The ISQ 7610 Single Quadrupole GC-MS System features user-centric innovations including instrument health monitoring assists you in determining when maintenance is needed to avoid unnecessary downtime. As a result, you maximize instrument utilization, sample throughput, and ultimately ROI.</p><h4><strong>Unstoppable confidence in your future</strong></h4><p>To ensure you are ready for any analytical challenge, the ISQ 7610 Single Quadrupole GC-MS System is fully upgradable from entry-level to advanced configurations. Now you can be confident that your laboratory can adapt to new challenges using the same investments in GC-MS technology.</p><h3><span><strong>Specifications</strong></span></h3><ul><li><span><strong>Mass Range: </strong>1.2–1100 u with unit mass resolution&nbsp;</span></li><li><span><strong>Type:&nbsp;</strong>Single Quadrupole GC-MS</span></li><li><span><strong>Detectors:&nbsp;</strong>Triple off-axis Thermo Scientific™ DynaMax™ XTEND XR detection system, with off-axis 10 kV dynode, discrete dynode electron multiplier and electrometer, linear from 0 to 110 μA</span></li><li><span><strong>Modes:&nbsp;</strong>Electron Impact Ionization (EI), with Full Scan (FS), SIM, and FS/SIM, Simultaneous within the same injection</span></li><li><span><strong>Scanning Capabilities:&nbsp;</strong>Fast Quadrupole Scanning up to 20,000 U/s</span></li><li><span><strong>Source Type:</strong>&nbsp;Advanced Electron Ionization (AEI) Source for Ultra-Sensitivity and Robustness</span></li><li><span><strong>Item Description:&nbsp;</strong>Scalable GC-MS platform, fully upgradable from a base configuration to an advanced highly sensitive configuration</span></li><li><span><strong>Description:</strong>&nbsp;ISQ 7610 Large Turbo, No VPI with AEI</span></li><li><span><strong>Mass Stability:&nbsp;</strong>Better than 0.1 u/48 hours/∆T ≤2 K</span></li><li><span><strong>Dimensions:</strong>&nbsp;46 x 36 x 69 cm (18 x 14 x 27 in) (H x W x D)</span></li><li><span><strong>Mass Analyzer:&nbsp;</strong>Dual-stage mass filter with off-axis ion guide pre-filter for noise reduction and solid, homogeneous non- coated, maintenance-free quadrupole rods</span></li></ul>

Thermo Scientific TSQ 9610 Triple Quadrupole GC-MS

The Thermo Scientific TSQ 9610 triple quadrupole GC-MS/MS systems is the best-in-class system for ultimate sensitivity and quantitation of targeted compounds. Optimized for high-throughput analytical laboratories.

<div><div id="product-description"><p><strong>To confidently stay ahead, your GC-MS/MS system must deliver ultimate performance while consistently producing trusted quantitative results. For this, turn to the Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System. User-centric Thermo Scientific™ NeverVent™ technology, extended-life detector, and intelligent software eliminate unnecessary downtime to maximize your sample throughput and return on investment (ROI). New extended linear dynamic range combined with proven high sensitivity ensures you keep ahead of the toughest regulatory methods and business demands.</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/mass-spectrometry/gas-chromatography-mass-spectrometry-gc-ms/gc-ms-systems/triple-quadrupole-gc-ms.html"><strong>Discover TSQ 9610 GC-MS highlights</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/store/instruments/configurators/trace1600"><strong>Build your GC-MS system</strong></a></li></ul></div><div><h4><strong>Increase instrument uptime</strong></h4><p>Eliminate unnecessary, unplanned instrument downtime to deliver high-confidence quantitative results, day after day. The TSQ 9610 Triple Quadrupole GC-MS/MS System combines unstoppable robustness with the ability to change the GC column and clean the ion source without interrupting analytical workflows.<br><br>Monitor key aspects of your GC-MS system. With Thermo Scientific™ SmartStatus™ instrument tracking within Chromeleon CDS, quickly see whether instruments are ready to run samples, if maintenance is required or if consumables should be replaced. The fully customizable software enables you to make data-driven decisions on when to perform maintenance and avoid unnecessary downtime.</p><h4><strong>Maximize sample throughput</strong></h4><p>When high sample throughput is essential, the system delivers results on time and with ease. Automated workflows and simplified operation ensure every user produces consistent results, sample after sample. Extended linear range and rapid selected reaction monitoring (SRM) scanning enable method consolidation so you can analyze more compounds in a single run. When these capabilities are combined with best-in-class uptime and sensitivity, you stay ahead of any productivity demand.</p><h4><strong>Realize rapid return on investment&nbsp;</strong></h4><p>Ensuring your system delivers results as soon as it’s installed is necessary to achieve rapid ROI. With built-in intelligence that simplifies instrument setup, analytical methods, and everyday operation, the TSQ 9610 Triple Quadrupole GC-MS/MS System is designed for accelerated deployment. Reduced needs for operator training and faster time to full productivity together with maximum sample throughput provide fast return on your instrument</p><h3><strong>TSQ 9610 GC-MS/MS highlights</strong></h3><h4><strong>Unstoppable confidence in quantitative performance</strong></h4><p>Delivering attogram-level sensitivity and best-in-class selected reaction monitoring (SRM) performance, the TSQ 9610 GC‑MS/MS system consistently meets required detection limits as you run samples. Choose the rugged Thermo Scientific ExtractaBrite ion source or the ultra-sensitive, ultra-robust Thermo Scientific Advanced Electron Ionization (AEI) ion source, depending on your sensitivity needs.</p><p>The XLXR electron multiplier detector which extends dynamic range twofold compared to the previous design. Extended dynamic range capability enables labs to combine methods, including calibration curve development, allowing analysis of low- and high-concentration compounds in a single run.</p><div container-id="cq-colctrl-lt0" comp-id="A2"><div><h4><strong>Unstoppable confidence in uptime for full-time productivity</strong></h4><p>The TSQ 9610 GC-MS/MS system is specifically designed for complex sample matrices in high-throughput applications.&nbsp;Using NeverVent technology with the Vacuum Probe Interlock (VPI) and V-Lock source plug, planned maintenance such as changing column and ion source cleaning can be performed without venting the mass spectrometer, increasing uptime. NeverVent technology is available on both the Thermo Scientific ExtractaBrite and the Thermo Scientific NeverVent Advanced Electron Ionization (NV-AEI) sources.</p></div></div><div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><h4><strong>Unstoppable confidence in your investment</strong></h4><p>Rapid instrument deployment reduces time to results and revenue generation. That’s why the TSQ 9610 Triple Quadrupole GC-MS/MS System includes a comprehensive set of automated tools to provide users with a seamless experience when transitioning from other platforms, developing methods, and analyzing samples. This built-in intelligence reduces operator training needs and time to full productivity for rapid ROI.</p></div></div></div><h4><strong>Unstoppable confidence in sample throughput</strong></h4><p>Maximizing sample throughput is essential to producing results on time. The TSQ 9610 Triple Quadrupole GC-MS/MS System incorporates user-centric innovations that extend service intervals, reduce maintenance, and allow methods consolidation to boost sample throughput while maintaining certainty in quality of results.</p></div></div>

Waters Xevo TQ-GC Mass Spectrometry System

The Xevo TQ-GC allows routine quantitation of multiple contaminants in matrix sample. The consistent high performance allows regulatory limits to be comfortably passed reducing the need for frequent user intervention and re-optimization.

<div><div><h4><strong>The perfect addition to your laboratory</strong></h4></div></div><div><div><p><strong>Demands to meet regulations are increasing pressure on laboratories, and in order to meet these challenges laboratories must develop and run methods that provide high-quality, consistent results, day in and day out.&nbsp;</strong></p><div><div><div><div><p>The <strong>Xevo TQ-GC</strong> is a robust <strong>Electron Ionization (EI) and Chemical Ionization (CI)</strong> Gas Chromatography (GC)-MS/MS platform that allows <strong>routine quantification of multiple contaminants in complex matrices</strong>. The <strong>Xevo TQ-GC</strong> consistently <strong>surpasses the sensitivity required to meet regulatory limits</strong>, thus reducing the need for frequent user intervention and re-optimization. In addition, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/635"><strong>MassLynx Software </strong></a><strong>security</strong> controls user access, giving you more control to assist with laboratory compliance.</p><p>Laboratories can also <strong>develop methods rapidly using Quanpedia</strong>, which allows fast response to changes in legislative demands and for customized methods. All the speed, sensitivity, and reliability you have come to expect from Xevo now with GC-MS/MS.</p><ul><li><strong>Reduce training time and costs</strong> with a single software workflow for GC-MS/MS and LC-MS/MS analysis</li><li><strong>Achieve comprehensive application coverage</strong> powered by Quanpedia database driven workflow</li><li><strong>Easily surpass regulatory limits</strong> with fit-for-purpose performance in difficult matrices</li><li><strong>Choose from a wide range of injection modes</strong>, including liquid, headspace, and solid phase microextraction (SPME) analysis</li><li><strong>Control access to the GC-MS system</strong> to meet regulatory requirements with MassLynx security</li><li><strong>Simplify maintenance tasks</strong> with a rapid and mistake-proof source design</li></ul></div></div><div><div><h4><strong>Recommended Use</strong></h4><p>For routine quantitation of multiple contaminants in an extracted matrix sample.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_4_fda01dffa7.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_4_fda01dffa7.jpg 245w," sizes="100vw" width="1024" height="606"></p><div><div><h3><strong>Maximize uptime to ensure your success</strong></h3><p>Ensuring you achieve <strong>reliable and predictable results</strong> is at the heart of the design of the Xevo TQ-GC. The system has been rigorously tested to ensure that you <strong>spend less time on routine maintenance</strong>, and that it can be scheduled to fit around the laboratory workload, <strong>maximizing uptime</strong> and <strong>minimizing disruption</strong>.</p><p>To ensure you don’t spend your precious time on lengthy instrument setup, <strong>Intellistart health check</strong> informs you whether the system is ready to run injections and, if not, how the situation can be remedied. Your lab only needs <strong>minimal tools for instrument maintenance</strong>, and if any maintenance is needed, it is <strong>fast and mistake-proof</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_5_ebae58fe9d.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Repeatability from replicate (n=200) injection of grape extract containing five pesticides at 0.01 mg/kg." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_5_ebae58fe9d.jpg 245w," sizes="100vw" width="1024" height="541"></p></div></div><div><div><h3><strong>Achieve efficiency and flexibility</strong></h3><p>In a busy analytical lab, time is precious, especially when demands change regularly and the requirement for shorter turnaround times is increasing. With <strong>Quanpedia</strong>, you can easily deal with a wide variety of sample matrices, target analytes and gas chromatography (GC) conditions. The <strong>fully customizable database</strong> means that you no longer need to be concerned about having the flexibility to adapt to changes in regulations, as it contains compound classes that are most relevant to regulations, and modifications to existing methods are quick and simple. You can reduce your method development time by including automatic scheduling of multiple reaction monitoring (MRM) transitions that account for any shift in retention times that occur because of column maintenance.</p><p>You can also <strong>shorten turnaround times</strong> by <strong>increasing the number of components in a single analytical run</strong>, which is enabled by <strong>acquisition rates of up to 500 MRM/sec</strong> with no significant degradation in performance. This means more MRM transitions can be added to a run while still achieving high quality results.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_caab24f949.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Generation of GC-MS acquisition and processing methods is performed automatically." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_caab24f949.jpg 245w," sizes="100vw" width="1024" height="546"></p></div></div><div><div><h3><strong>Capture the whole picture in targeted analyses</strong></h3><p>Reduce the risks to method performance and data quality associated with undetected interferences and unexpected compounds when conducting targeted analysis. <strong>RADAR improves method development and aids troubleshooting</strong> with the ability to detect and confirm analytes not specifically targeted through NIST library confirmation and routinely characterize unexpected contaminants. With this additional information, you can be completely confident in your data and avoid additional confirmatory analyses.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_2_48915d33e6.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Use of RADAR and NIST library search to identify a co-extracted compound in green tea matrix." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_2_48915d33e6.jpg 245w," sizes="100vw" width="1024" height="286"></p></div></div><div><div><h3><strong>Confidently meet regulatory demands</strong></h3><p>To ensure confidence in results, most analysts would prefer to operate comfortably below regulatory limits. You can achieve this confidence with Xevo TQ-GC, not only through <strong>reliable high performance</strong> but also as a result of <strong>TargetLynx</strong>, an Application Manager common across Waters LC and GC platforms. This means it not only gives full analyte quantification, simplified review of results, and customizable reporting, but also provides a common platform between instrument types simplifying data processing and reducing time to results.</p><p>With <strong>Waters MassLynx Basic Security</strong>, you are in control. Ideal for laboratories who need to manage or control access to a GC-MS system. MassLynx Basic Security contains an events audit log for added traceability for audits and accreditation, and the security can also be used with TargetLynx acquisition software.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_3_a0c5238bfe.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Comprehensive and streamlined results review with TargetLynx flags any results outside user-defined tolerances." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_3_a0c5238bfe.jpg 245w," sizes="100vw" width="1024" height="499"></p></div></div></div></div></div></div></div></div>

Products from category Mass detectors - page 3

Related content

Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window

Deadline for RAFA 2026 Early Registration and Oral Abstract Submission is approaching

Let’s call a PT scheme a PT scheme!