Wiley has released the NIST/EPA/NIH EI Mass Spectral Library 2026 and NIST MS/MS Spectral Library 2026, featuring expanded spectral collections, updated search software, and separate EI and MS/MS products.

Learn how to use MS Interpreter in NIST 26 to interpret accurate-mass EI GC-MS spectra, verify library hits, compare candidate structures, and improve compound identification.

Learn how to create retention index calibrations in NIST 26, calculate RI values automatically, and improve GC-MS compound identification by combining spectral library searching with retention indices.

Learn how NIST 26 Hybrid Search expands EI GC-MS library searching by identifying structurally related compounds using mass-shifted fragment matching, DeltaMass analysis, and MS Interpreter validation.

Learn how to use NIST 26 Lib Search with spectra sent from the Chromatogram Window, compare Full Spectrum and Reverse searches, and improve EI GC-MS identifications.

Learn how to process accurate-mass GC-MS data in NIST 26 using integrated deconvolution, library searching, MS Interpreter validation, filtering tools, and Excel reporting workflows.

Learn how to process EI GC-MS data in NIST 26 using integrated AMDIS deconvolution, library searching, filtering, spectral review, and Excel reporting for confident compound identification.

Learn how to configure, customize, and navigate the new NIST 26 Chromatogram Window. This practical guide covers layouts, zooming, filtering, structure display, and efficient data review workflows.

NIST EI Search V4.0 (2026) introduces integrated GC/MS deconvolution, accurate mass EI data support, and an expanded EI library with more than 431,000 spectra for more confident compound identification.