Thermo Scientific™ Exactive™ GC Orbitrap™ GC-MS System

Bringing high-resolution Orbitrap technology into routine GC-MS workflows

The Exactive GC Orbitrap system offers the unmatched mass accuracy, resolving power, and sensitivity of Orbitrap technology in a platform optimized for routine applications. This high-performance GC-MS system enables both targeted and non-targeted full-scan workflows with confident quantitation and trace-level detection, even in complex matrices. Designed for maximum robustness and usability, it streamlines operations across food safety, environmental, industrial, forensic, and anti-doping laboratories.

Key Features and Benefits

💡 Unmatched HRAM Performance

• Resolving power up to 60,000 FWHM at m/z 200
• Mass accuracy: <1 ppm (internal), <3 ppm (external)
• Quantitative dynamic range: >10⁶, with excellent linearity and precision
• Routine IDLs in the sub-ppb to ppt range

🧪 Full-Scan Sensitivity and Selectivity

• Combines triple-quad-like quantitation with full-scan Orbitrap capability
• Sub-ppb sensitivity for 100+ pesticides in food matrices
• High selectivity and confidence in trace-level compound identification
• Spectral deconvolution with accurate-mass fragment filtering

⚙️ Proven Orbitrap Design

• Curved linear trap (C-Trap) and bent flatapole ion optics
• ExtractaBrite™ ion source (EI/PCI/NCI) – removable under vacuum
• Vent-free column exchange using patented source plug
• Optional direct sample probes (DIP, DEP) for solid or thermolabile analytes

🧠 Streamlined Software and Data Processing

• Controlled by TraceFinder™ and Xcalibur™ platforms
• Full-scan acquisition with automated data mining
• Integrated spectral libraries (NIST, Thermo Food/Environmental)
• Spectral fidelity and mass accuracy retained across wide concentration range

🔁 Optimized GC Integration

• Built on the TRACE™ 1310 GC platform
• Supports all injection/detection configurations (SSL, PTV, backflush, etc.)
• Paired with TriPlus™ RSH autosampler for advanced robotic sample handling
• Excellent retention time stability and fast oven cycling

Ideal For Applications In:

• Food safety and authenticity (pesticide screening, additives)
• Environmental analysis (contaminants, pollutants, air toxics)
• Forensics and toxicology (unknowns, drugs, metabolites)
• Industrial QC (extractables, volatiles, impurity profiling)
• Non-targeted screening with full-scan HRAM and retrospective analysis

Thermo Scientific™ Exactive™ GC Orbitrap™ GC-MS System