The Paradigm Flow Modulator with Reverse Fill-Flush (RFF) technology dramatically expands chromatographic peak capacity across the full volatility range while preserving quantitative accuracy. The RFF modulator fills a fixed-volume sample loop with effluent from the first-dimension column and then rapidly flushes it onto an orthogonal second-dimension stationary phase. This true comprehensive GC×GC transfer ensures excellent repeatability, robust quantitation, and high-quality separations for complex samples.
Paradigm eliminates complex offline flow calculations. Integrated ChromaTOF® software automatically performs all required calculations via a straightforward interface. The resulting methods are optimized to deliver complete analyte transfer, excellent peak shapes, and high chromatographic resolution—without manual trial-and-error.
LECO Paradigm Flow Modulator and Shift Flow Splitter: ChromaTOF Software identifies method calculation improvements for RFF modulation
The Shift Flow Splitter introduces a novel splitting mechanism that maintains a constant split ratio between MS and FID across the full GC oven program. Compared to traditional splitters, Shift delivers superior quantitative accuracy with minimal internal standardization, greatly simplifying compound-level and group-type quantitation in GC and GC×GC workflows.
LECO Paradigm Flow Modulator and Shift Flow Splitter: Close-up on the Shift Flow Splitter installed in a GC oven
ChromaTOF automatically balances and optimizes the flow directed to TOFMS and FID, ensuring proper peak shapes and matched sensitivity for reliable qualitative and quantitative results.
LECO Paradigm Flow Modulator and Shift Flow Splitter: ChromaTOF Software automatically optimizes flow rates
