<p><strong>Clarity 10.2 expands instrument control capabilities with new control modules and updates the MS extension to help you work more efficiently.</strong></p><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity</strong></a><strong> 10.2 highlights</strong></h4><ul><li>New and updated control modules</li><li>Improved MS data import and export</li><li>Obsolete hardware support ended</li></ul><h4><strong>Instrument control modules</strong></h4><p>Clarity 10.2 introduces new instrument control modules from Annuo (AS-3117, FAS-3823) and updated instrument controls form Sykam and Ecom.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Instrument_control_modules_5de26782b0.jpg" alt="DataApex: Instrument control modules" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Instrument_control_modules_5de26782b0.jpg 228w," sizes="100vw" width="380" height="260"></p><h4><strong>MS data import/export improvements</strong></h4><p>Clarity improves MS data exchange, especially for *.cdf files. MS instruments now support export and import of multiple spectral data and non-spectral signal data in the same CDF file. Import also better handles uniform sampling information, m/z Step values, scale factors, and file names with non-ASCII characters. Exporting individual chromatogram signals from MS instruments is now available through a separate Export Chromatogram dialog.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg" alt="DataApex: MS data import-export improvements" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_MS_data_import_export_improvements_a7967a4020.jpg 228w," sizes="100vw" width="378" height="259"></p><h4><strong>Obsolete hardware support terminated</strong></h4><p>Due to changes in Windows driver security requirements, this update discontinues support for obsolete hardware, including INT7, INT9, U-PAD, U-PAD2, and CB20.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg" alt="DataApex: Obsolete hardware support terminated" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Data_Apex_Obsolete_hardware_support_terminated_24d9329419.jpg 228w," sizes="100vw" width="378" height="259"></p><blockquote><p><strong>Explore the complete list of all changes, fixes, and additions in version 10.2.</strong></p><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1"><strong>See the complete changelog&nbsp;</strong></a></p></blockquote>

Clarity Chromatography Software 10.2 released!

<p><strong>Traditional EI library searching works exceptionally well when the unknown compound is already present in the spectral library. However, analytical chemists frequently encounter compounds that are structurally related to library entries but are not exact matches. NIST's EI Hybrid Search addresses this challenge by combining conventional spectral matching with mass-shifted fragment alignment, allowing the identification of analogs, derivatives, and novel compounds that may not exist in the database.</strong></p><p>This guide summarizes the workflow presented by James Little and demonstrates how to use NIST 26 Hybrid Search in conjunction with the Chromatogram Window and MS Interpreter to obtain more meaningful structural information from unknown EI GC-MS spectra.</p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/33370"><strong>You can download PDF Handout for this guide HERE</strong></a></p></blockquote><h4><strong>Why Hybrid Search Matters</strong></h4><p>Conventional EI library searching relies on direct matching between an unknown spectrum and spectra stored in a library. Hybrid Search expands this concept by allowing fragment ions to be matched even when they are shifted by a consistent mass difference (Δm). This enables the software to recognize compounds that differ by substituents or structural modifications.</p><p><strong>Key advantages include:</strong></p><ul><li>Identification of structurally related compounds not present in the library</li><li>Detection of analogs, derivatives, and emerging compounds</li><li>Integration of exact fragment matches and mass-shifted matches into a single score</li><li>Improved interpretation of unknowns through proposed structural modifications</li><li>Enhanced confidence when molecular weight information is available</li></ul><p>Although Hybrid Search does not require the molecular ion to be present, performance improves significantly when the molecular weight can be estimated or constrained. In these cases, the observed mass difference between the unknown and library compounds can often be translated directly into a plausible chemical modification.</p><h4><strong>Configuring Hybrid Search</strong></h4><p>Before performing a search, the Hybrid Search settings should be configured within the NIST Library Search window.</p><p>Recommended settings:</p><ul><li>Select the Similarity search mode</li><li>Enable Hybrid Search</li><li>Keep the In Spectrum option checked under normal circumstances</li><li>Allow the software to estimate the molecular weight automatically</li><li>If the estimated molecular weight appears incorrect, manually enter a nominal molecular weight</li><li>Select all relevant libraries (NIST, Wiley, user libraries, etc.)</li><li>Save the configuration for future use</li></ul><p>The selected molecular weight used to constrain the search is displayed in the lower-right corner after the search is completed.</p><h4><strong>Optimizing the Results Display</strong></h4><p>Hybrid Search produces several unique parameters that are not shown in the default results table.</p><p>Additional columns should be added by right-clicking within the results table and selecting Properties. Recommended columns include:</p><ul><li>DeltaMass</li><li>dForm</li><li>pctRelForm</li><li>o.Match (equivalent to the traditional EI Normal Match score)</li></ul><p>Without these parameters, much of the structural interpretation power of Hybrid Search is lost.</p><h4><strong>Working with Spectra from the Chromatogram Window</strong></h4><p>Currently, the Chromatogram Window performs standard EI library searching. When a potentially interesting unknown is encountered:</p><ul><li>Perform the normal EI search in the Chromatogram Window</li><li>Send the spectrum to the standalone Library Search module</li><li>Perform a Hybrid Search using the enhanced Hybrid Search functionality</li></ul><p>This workflow combines rapid screening with advanced structural interpretation.</p><h4><strong>Understanding Key Hybrid Search Parameters</strong></h4><h5><strong>DeltaMass (Δm)</strong></h5><p>DeltaMass represents the mass difference between the unknown compound and the matched library compound.</p><p>A consistent Δm across multiple high-scoring hits often indicates a specific structural modification.</p><h5><strong>dForm</strong></h5><p>dForm provides a proposed elemental composition that explains the observed mass difference.</p><p>Examples include:</p><ul><li>H–1F</li><li>CH₂</li><li>O–1</li><li>C₁H₃F</li></ul><p>These transformations can suggest likely chemical modifications between the library compound and the unknown.</p><h5><strong>pctRelForm</strong></h5><p>New in NIST 26, pctRelForm estimates how frequently a given elemental transformation occurs relative to the most common transformation (CH₂ = 100%).</p><p>Interpretation:</p><ul><li>High values indicate chemically plausible and commonly observed transformations</li><li>Very low values suggest the proposed transformation may be accidental or unlikely</li></ul><h5><strong>o.Match</strong></h5><p>Represents the traditional EI match score and allows comparison between standard searching and Hybrid Search results.</p><h4><strong>Case Study: Identifying a Fluorinated Unknown</strong></h4><p>The presentation demonstrates the identification of an unknown compound with a proposed molecular weight of 152 Da.</p><p>Hybrid Search returned several high-scoring hits with consistent evidence suggesting fluorine substitution:</p><p><strong>Hit #1</strong></p><ul><li>Library MW: 134</li><li>DeltaMass: +18</li><li>dForm: H–1F</li><li>Interpretation: Addition of fluorine</li></ul><p><strong>Hit #5</strong></p><ul><li>Library MW: 138</li><li>DeltaMass: +14</li><li>dForm: CH₂</li><li>Interpretation: Related fluorinated analog</li></ul><p><strong>Hit #6</strong></p><ul><li>Library MW: 168</li><li>DeltaMass: –16</li><li>dForm: O–1</li><li>Interpretation: Structurally consistent fluorinated compound</li></ul><p>Multiple independent hits converged on the same conclusion: the unknown was likely a fluorinated analog of known aromatic compounds.</p><p>This illustrates the major strength of Hybrid Search: identifying structural relationships even when the exact compound is absent from the library.</p><h4><strong>Moving from Hybrid Search to Structural Interpretation</strong></h4><p>Once a plausible structure is identified:</p><h5><strong>Step 1 – Export the Structure</strong></h5><p>From the Hybrid Search results:</p><ul><li>Right-click the best hit</li><li>Use Send To → Default Structure Editor</li><li>Open the structure in a drawing program such as ChemSketch</li><li>Copy the proposed structure to the clipboard</li></ul><h5><strong>Step 2 – Open MS Interpreter</strong></h5><p>Within MS Interpreter:</p><ul><li>Paste the proposed structure</li><li>Load the unknown spectrum</li><li>Compare predicted fragmentation with observed ions</li><li>Evaluate isotope patterns and fragment assignments</li></ul><h5><strong>Step 3 – Validate the Proposal</strong></h5><p>Indicators of a good structural proposal include:</p><ul><li>Consistent isotope ratios</li><li>Logical fragmentation pathways</li><li>Agreement between observed and predicted fragment ions</li><li>Multiple Hybrid Search hits supporting the same structural modification</li></ul><p>In the example presented, MS Interpreter showed excellent agreement between the proposed fluorinated structure and the observed EI spectrum, although the exact positions of the fluorine and methyl substituents on the aromatic ring could not be definitively assigned.</p><h4><strong>Best Practices</strong></h4><ul><li>Always review DeltaMass, dForm, and pctRelForm together</li><li>Do not rely solely on the highest match score</li><li>Give greater weight to transformations supported by multiple independent hits</li><li>Use molecular weight information whenever possible</li><li>Confirm structural hypotheses using MS Interpreter</li><li>Consider Hybrid Search as a structure-elucidation tool rather than simply a library search tool</li></ul><h4><strong>Conclusion</strong></h4><p>NIST 26 Hybrid Search significantly extends the capabilities of conventional EI library searching by identifying structural relationships between unknown compounds and library entries. Through the use of DeltaMass calculations, elemental transformation analysis (dForm), and statistical plausibility metrics (pctRelForm), Hybrid Search provides valuable clues for elucidating compounds that are absent from spectral libraries.</p><p>When combined with MS Interpreter, it becomes a powerful workflow for the characterization of unknowns, analogs, degradation products, metabolites, and emerging compounds in EI GC-MS analysis.</p>

Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 22nd June 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you brochure by <strong>Agilent Technologies, </strong>application note<strong> </strong>by<strong> Shimadzu </strong>and posters by <strong>MDCW / William &amp; Mary </strong>and <strong>Waters Corporation / ASMS!</strong></p><h3><strong>1. Agilent Technologies: Operational efficiency for your GC and GC/MS labs with the </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890B"><strong>Agilent 8890B gas chromatography system</strong></a></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/br_8890b_gc_5994_9205en_agilent_fb5db29527.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><h4><strong>Analyze more samples every day with faster cycle times&nbsp;</strong></h4><p>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890B"><strong>8890B GC </strong></a>provides faster maximum oven temperature ramps and cooldown rates for conventional dual-channel GC. If you want even faster cycle times, an optional rapid cooling fan is available.&nbsp;</p><h4><strong>Achieve excellent repeatability across multiple injections&nbsp;</strong></h4><p>Consistent retention time and area count performance are the cornerstone of what you can expect from the 8890B GC. The system also meets all specifications required for regulatory methods such as USP Method &lt;467&gt; (residual solvents).</p><h4><strong>Shine a new light on your connections and components&nbsp;</strong></h4><p>Make maintenance easier and faster with a built-in oven light that illuminates the internal space on the 8890B GC. That means you can perform tasks like troubleshooting and column installation in less time—and with fewer errors.</p><h4><strong>Boost GC performance with capillary flow technology&nbsp;</strong></h4><ul><li><strong>Backflush</strong> significantly reduces timing between injections, increasing productivity.&nbsp;</li><li><strong>Purged Ultimate unions</strong> provide leak-free connections, reducing downtime.&nbsp;</li><li><strong>Flow splitters</strong> enable data collection from up to three detectors.&nbsp;</li><li><strong>New CFT calculators</strong> let you download calculated setpoints to your method—avoiding time-consuming, error-prone manual input.&nbsp;</li><li><strong>Multidimensional chromatography:&nbsp;</strong><ul><li><strong>Deans Switch</strong> facilitates heart cutting, enabling resolution of trace compound in complex matrices.&nbsp;</li><li><strong>GC x GC flow modulation</strong> enables multidimensional chromatography without the need for cryogen</li></ul></li></ul><h4><strong>Helium conservation module&nbsp;</strong></h4><p>Extend the life of your helium tanks by up to 30 times. The Agilent helium conservation module allows you to use helium for your GC runs and switch to a different gas (typically nitrogen) when your GC is idle. That means you can achieve better control of laboratory operating expenses and avoid workflow disruptions.</p><h4><strong>Alternative carrier gas support&nbsp;</strong></h4><p>Alternative carrier gases like hydrogen and nitrogen are popular low-cost options.&nbsp;</p><p>The <strong>Agilent Hydrogen Sensor Module Series 2 </strong>option adds built-in peace of mind when operating with H2 gas.&nbsp;</p><p>The <strong>Agilent HydroInert source </strong>minimizes sensitivity loss and spectral anomalies associated with H2. It also:&nbsp;</p><ul><li>Maintains spectral fidelity, even for compounds highly susceptible to hydrogenation.&nbsp;</li><li>Improves peak shape for high-boilers, especially polycyclic aromatic hydrocarbons (PAHs)</li></ul><h3><strong>2. MDCW / William &amp; Mary: Decomposition Analysis Using Differing Data Processing Methods to Identify Volatile Organic Compounds</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/P_25_Weina_2ae94f0998.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>When a body decomposes it emits volatile organic compounds (VOCs). VOCs from decomposing remains have been studied before,1 however there is a gap that remains in the knowledge on VOCs that evolve from submerged decomposing remains. 2 In this study, submerged animal tissue was tested to see how the VOCs can be utilized in forensic settings.&nbsp;</p><p>This study used data obtained last summer using comprehensive two-dimensional gas chromatography – time-of-flight mass spectrometry (GC×GC-TOFMS). Pigs (Sus scrofa domesticus) are often used as analogs in decomposition studies due to similarities with humans. 3 In this study, pork belly samples were submerged in mason jars filled with water and stored at different temperatures. The GC×GC-TOFMS instrument was used to collect odor from above water samples for a period of twelve days.</p><p>GC×GC is often used to analyze complex odor profiles. When analyzing samples with GC×GC, there is a lack of standardization to process the data acquired from time trials. There is a need to discover effective ways to track VOCs for chemical identification and longitudinal analysis.</p><p>The goal of this research was to compare different software approaches to analyze GC×GC longitudinal data to achieve accurate analyte identification, representation of data over time, and effective class characterization.</p><h4><strong>Methods</strong></h4><p>For the first four days, 5 mL of water was taken and run on the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/37"><strong>GC×GC-TOFMS</strong></a>. Thereafter, the samples were sampled and run every three days until day twelve. Data were analyzed initially using <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/41"><strong>ChromaTOF</strong></a> (LECO Corporation). The samples were then analyzed using <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/348"><strong>ChromaTOF Tile </strong></a>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1873"><strong>ChromaTOF Sync 2D</strong></a> to compare how they can be used in a forensic setting.</p><p>Peak tables were curated in Tile and Sync 2D. Then, ChromaTOF was used as a guide to confirm which peaks were identified correctly. If the compound was correctly identified, the peak would be accepted or kept on the table. If not correctly identified, the peak would either be rejected or deleted. Once the tables were complete from the different software approaches, they were exported to Excel for further comparison.</p><p>In excel, the relevant hits that were identified as decomposition VOCs were compared across the software approaches. The compounds that were most commonly found were compared to existing literature on decomposition VOCs. From there, two tables were built; where one table was compounds confirmed with literature and the other table was compounds not confirmed with literature.</p><p>Comparison between software approaches included looking at different criteria to see which method was the most effective and efficient. The criteria included how long the software approach took, the number of compounds found in each software approach, the accuracy of peak area in the software approach compared to ChromaTOF data, and principal component analysis (PCA) comparison to see which software approach was best used for forensic practice or research.</p><h4><strong>Conclusions</strong></h4><p>Sync 2D showed the capability of showing trends in decomposition compounds</p><ul><li>This software approach can be used in research environment where longitudinal data is needed to determine the trends of decomposition data&nbsp;</li><li>Best purpose: research applications requiring longitudinal tracking&nbsp;</li></ul><p>Coefficient of Variance’s and Fold Change’s PCA plots showed their ability for clear class differentiation&nbsp;</p><ul><li>The two software approaches can be used to distinguish water containing decomposition in a crime scene&nbsp;</li><li>Best purpose: comparison at a single point and time [detailed analysis]&nbsp;</li></ul><p>Fisher Ratio showed a proficiency in identifying top differentiating compounds and showed aptitude for class differentiation&nbsp;</p><ul><li>The software approach would be helpful for cursory analysis for crime scene evidence&nbsp;</li><li>Best purpose: quick comparison of biggest difference for swift identification</li></ul><h3><strong>3. Shimadzu: Determination of Ester and Linolenic Acid Methyl Ester Contents in Biodiesel According to EN 14103:2020</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_05_sca_180_054_en_93d1029b72.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=2060"><strong>NexisTM GC-2060</strong></a> provides reliable analysis of biodiesel samples regarding their ester and linolenic acid methyl ester contents using hydrogen as a cost-effective carrier gas&nbsp;</li><li>It delivers excellent repeatability and provides appropriate safety measures for the use of hydrogen as carrier gas&nbsp;</li><li>The optional multi-mode injection unit (MMI) offers performance equivalent to a conventional split-splitlessinjection unit (SPL), significantly reducing maintenance downtime</li></ul><p>Biofuels play an important role in enabling countriesto meet their greenhouse gas reduction targets. They can be produced from a range of raw materials, including plant oils, animal fats, and used cooking oils. Biodiesel is mainly being produced from rapeseed, soybean, and palm oils. Due to this diversity of feedstocks, continuous quality control is necessary as the quality of the raw material has an enormousimpact on the quality of the biodiesel.&nbsp;</p><p>The EN 14103:2020 describes the determination of total ester content and linolenic acid methyl ester content in biodiesel by means of gas chromatography with flame ionization detection (GC-FID). The total ester content covers a range of fatty acid methyl esters (FAME) from C6 to C24, and linolenic acid methyl ester is investigated separately as interfering reactive compound that might influence long-term stability of the biodiesel. According to the standard, the total ester content must be greater than 90 % (m/m) and the linolenic acid methyl ester content shall be between 1 and 15 % (m/m)1.</p><p>This study shows the analysis of biodiesel originating from rapeseed,soybean, and palm oil using the Nexis GC-2060.</p><h4><strong>Multi-Mode Injection Unit as Alternative&nbsp;</strong></h4><p>Shimadzu’s multi-mode injection unit (MMI) offers reliable splitsplitless mode functionality over a broad range of carbon numbers. It allows analysis of biodiesel samples with high repeatability and provides chromatographic results comparable to those measured with SPL as dedicated split-splitless injection unit. The use of MMI significantly shortens maintenance downtime from tens of minutes for a classical split-splitless injection unit to just a few minutes. Figure 3 gives a direct comparison of an exemplary rapeseed-based biodiesel sample measured with SPL (top) and MMI (bottom).</p><h4><strong>Conclusion</strong></h4><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=2060"><strong>Nexis GC-2060</strong></a> provides reliable analysis of biodiesel samples regarding their ester and linolenic acid methyl ester content according to EN 14103:2020, covering the various ester types commonly in use. It allows repeatable analysis using hydrogen as a cost-effective carrier gas. The optional multi-mode injection unit (MMI) can be selected as alternative to a classical splitsplitlessinjection unit (SPL).</p><h3><strong>4. Waters Corporation / ASMS: Putting the (Atmospheric) Pressure on Forever Chemicals: A Targeted Analysis of GC Amenable PFAS using APGC–MS/MS</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/720009413_dfa4082b45.pdf"><strong>Full PDF for download</strong></a></li></ul><p>This poster presents a targeted analytical method for the determination of gas chromatography (GC)-amenable PFAS compounds using atmospheric pressure gas chromatography coupled with tandem mass spectrometry (APGC-MS/MS). The study addresses a key limitation of conventional LC-MS/MS methods, which are highly effective for many PFAS but less suitable for more volatile species such as fluorotelomer alcohols (FTOHs), fluorotelomer acrylates (FTAcr), and fluorotelomer acetates (FTOAc). By incorporating GC-MS/MS analysis, laboratories can obtain a more complete characterization of PFAS contamination across environmental, biological, and food-contact materials.</p><p>The analytical workflow utilized an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890"><strong>Agilent 8890 gas chromatograph</strong></a> equipped with an autosampler and coupled to a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/554"><strong>Waters Xevo TQ Absolute tandem mass spectrometer</strong></a> operated with APGC ionization in positive-ion mode. Separation was performed on an Rtx-200 capillary column, while data acquisition and quantification were managed using <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1544"><strong>waters_connect software</strong></a>. Unlike traditional electron ionization (EI), APGC generated intact protonated molecular ions, significantly improving sensitivity and selectivity for GC-amenable PFAS. A method covering 35 PFAS compounds was developed, achieving lower limits of quantification (LLOQs) of 0.025–0.1 ng/mL for most analytes.</p><p>Several sample types were evaluated, including wastewater, surface water, soil, fish tissue, shrimp, and food-packaging materials. Environmental and biological samples were prepared according to EPA Method 1633A and had previously been analyzed by LC-MS/MS, allowing the GC-MS/MS method to serve as a complementary technique. Food-packaging samples were extracted with methanol containing ammonium hydroxide and analyzed for targeted PFAS. While no target PFAS were detected in the tested packaging materials, multiple GC-amenable PFAS were found in environmental samples. Fluorotelomer alcohols were the most frequently detected compounds, with wastewater and ski-wax-impacted soils showing the highest concentrations.</p><p>The results demonstrate that APGC-MS/MS provides a sensitive and robust solution for the analysis of volatile PFAS classes that may be missed by LC-MS/MS alone. The method delivered accurate quantification, effective chromatographic separation, and reliable recovery in spiked samples. The authors conclude that combining APGC-MS/MS with established LC-MS/MS workflows enables a more comprehensive assessment of PFAS contamination, particularly for emerging fluorotelomer compounds and other GC-amenable PFAS that are increasingly relevant in environmental monitoring and food-packaging investigations.</p></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 26, 2026

Article

Product

Application

Academy

Video

Software

Poster

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

Agilent Technologies

Phenomenex

Thermo Fisher Scientific

Restek Corporation

<p><strong>Have you ever seen analyte peaks show up in a blank, or extra peaks suddenly appear out of nowhere?</strong></p>
<p>It is likely that you have some carryover or contamination in your system. Contamination that creates ghost and carryover peaks can be introduced at different points, including sample preparation, introduction, and separation. The additional peaks can cause false positive identifications and/or inaccurate quantitative results. </p>
<p>Join us as we discuss the most common sources of carryover and how to address them.</p>
<blockquote>
<p><strong>Presenter:</strong> Alex Ucci (Application Engineer, Agilent Technologies, Inc.)</p>
</blockquote>
<blockquote>
<p>In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.</p>
</blockquote>


Agilent Technologies: Don’t Get Carried Away by Carryover: Troubleshooting GC Chromatography

Don’t Get Carried Away by Carryover: Troubleshooting GC Chromatography

The most common sources of carryover and how to address them.

Troubleshooting GC Chromatography

<p><strong>Injecting water into your GC may be convenient, especially if you are working with compounds that have limited solubility in organic solvents or with water samples. However, there are many potential problems with water, including injector and detector issues.</strong></p>
<p>Join us as we take a dive deep and explore water injections and not only how to perform them correctly, but also the many pointers to keep in mind when working with water.</p>
<blockquote>
<p><strong>Presenter:</strong> Mark Sinnott (Application Engineer, Agilent Technologies, Inc.)</p>
</blockquote>
<blockquote>
<p>Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Twin Falls Idaho.</p>
</blockquote>


Agilent Technologies: Navigating Troubled Waters: A Deep Dive into Water Injections by GC

Navigating Troubled Waters: A Deep Dive into Water Injections by GC

Water injections and not only how to perform them correctly, but also the many pointers to keep in mind when working with water in GC.

A Deep Dive into Water Injections by GC

<h3><strong>PhenoAcademy Webinars - Gas Chromatography Series</strong></h3>
<h4><strong>Introduction to Gas Chromatography and Method Development</strong></h4>
<ul>
<li><p>Learn about basic Gas Chromatography theory, and review the GC System such as injectors, oven, detectors</p>
</li>
<li><p>Understand the correlation between efficiency, selectivity, and retention to the GC settings and components</p>
</li>
<li><p>Receive an overview on available phases, and an introduction to method development</p>
</li>
</ul>
<blockquote>
<p><strong>Presenter</strong>: Duilio Romanello (Senior Technical Specialist, Phenomenex)</p>
</blockquote>
<blockquote>
<p>Duilio Romanello graduated with his Bachelors of Science in Pharmaceutical Chemistry and Technology from University of Bologna. Duilio then joined Phenomenex in 2008 as an Inside Technical Sales Consultant becoming Team Leader in Italy for GC/SPE in 2010 and then for the Environmental &amp; Food Team.</p>
</blockquote>
<blockquote>
<p>Since 2016 he has been covering the role of  Account Manager for the South of Italy working remotely and acting as GC Specialist. Since November 2023 he is Senior Technical Specialist for the Technical team at Phenomenex.</p>
</blockquote>
<blockquote>
<p><strong>Presenter</strong>: Zachary Woodward (Senior Technical Specialist, Phenomenex)</p>
</blockquote>
<blockquote>
<p>Zachary Woodward is a Senior Technical Specialist with Phenomenex, Inc, assisting laboratories with method development in the bio-pharma, environmental, and food industries.  Zachary spent his formative years developing HPLC and GC methods with a pharmaceutical lab in Albany, NY, after which he developed HPLC and SPE methods in the clinical setting here in Southern California.  Zachary received his B.Sci. in Chemistry from the College of William and Mary, was awarded his Master’s in Chemistry at San Diego State University, and is happy to speak with you today!</p>
</blockquote>
<blockquote>
<p><strong>Presenter</strong>: Lucia Geis Asteggiante (Senior Technical Specialist, Phenomenex)</p>
</blockquote>
<blockquote>
<p>Lucia is a Senior Technical Specialist that has recently joined Phenomenex’s Global Technical Team. She has a broad experience in the field of Analytical Chemistry with a particular focus on LC chromatography coupled with mass spectrometry. Lucia comes from a strong academic and regulatory background with experiences ranging from method development and analysis of small molecules to large protein complexes. She gained her Ph.D. at the University of Maryland - College Park, USA and did her post-doctoral work at the University of Oxford, UK. During her time as a researcher, she has authored/co-authored 23 scientific publications and 2 book chapters.</p>
</blockquote>


Introduction to Gas Chromatography and Method Development 

Gas Chromatography theory, and review of the GC System such as injectors, oven, detectors

Introduction to Gas Chromatography and Method Development

<p><strong>The quality and safety of pharmaceutical products are the top concerns of regulators. In recent years, regulatory agencies and pharmacopeia&#39;s have strengthened their position on preventing drug adulteration in both active pharmaceutical ingredients (API) and excipients by enacting new regulations and developing new documentary and reference standards.</strong></p>
<ul>
<li>In May’23, USFDA released ‘Guidance for Industry’ mentioning about quantitative testing of DEG and EG levels for representative samples of each shipment of each lot before use in product manufacturing by gas chromatography (GC) instrument.</li>
<li>Ministry of Commerce &amp; Industry (INDIA) also released notification for amendment in Chapter-30 of Schedule 2 (Export Policy) related to export of Cough Syrups.</li>
<li>WHO is also focusing on targeted quality testing of medicinal syrups imported to Rest of the World &amp; Developing nations to confirm quality &amp; compliance of syrups with respect to DEG &amp; EG levels.</li>
</ul>
<p><strong>Join this webinar to hear IPC, USP and Agilent experts share their views on:</strong></p>
<ol>
<li>Role of Pharmacopeia&#39;s in ensuring Quality of Pharmaceutical products and excipients</li>
<li>Importance of Excipient Quality to Medicine Quality</li>
<li>Understanding of high-risk excipients</li>
<li>Advanced workflows to comply with latest regulatory and Pharmacopeial updates</li>
</ol>
<blockquote>
<p><strong>Presenter</strong>: Dr. Tong (Jenny) Liu (Principal Scientist in Global Science and Standards - Excipients, United States Pharmacopeia)</p>
</blockquote>
<blockquote>
<p>Dr. Tong (Jenny) Liu is a Principal Scientist in Global Science and Standards — Excipients at the United States Pharmacopeial (USP). She is currently responsible for the development, update, and harmonization of excipient monographs and excipients-related general chapters under the work plan of the Pharmacopeial Discussion Group (PDG). PDG strives for the harmonization of compendial standards among European Pharmacopeia, Indian Pharmacopeia, Japanese Pharmacopeia, and the United States Pharmacopeia.</p>
</blockquote>
<blockquote>
<p>Dr. Liu has 20+ years of experience in analytical method development and validation for pharmaceutical products. She received her Ph.D. in chemistry from Boston University, Boston, USA. Supported by NIH Fellowship, she performed post-doctoral research in the Department of Chemical Biology, Ernest Mario School of Pharmacy in Rutgers University, New Jersey, USA.</p>
</blockquote>
<blockquote>
<p><strong>Presenter</strong>: Mr. Arvind Kumar Sharma (Scientific Assistant, Indian Pharmacopoeia Commission, Ministry of Health &amp; Family Welfare - Government of India)</p>
</blockquote>
<blockquote>
<p>With six years of experience as a Scientific Assistant at Indian Pharmacopoeia Commission, he has played a key role in the current development of Indian Pharmacopoeia Reference Substances (IPRS) and Impurity Reference Substances. He has been engaged in the preparation and updating of draft monographs for publishing in Indian Pharmacopoeia (IP). Additionally, he has played a major role in the development of the latest edition of the National Formulary of India 2021 and has been involved in work related to the Pharmacovigilance Programme of India (PvPI). He holds a a M. Pharmacy in Pharmacology from Sinhgad Institute of Pharmaceutical Sciences, Pune and a B. Pharmacy from the College of Pharmacy, IPS Academy Indore. He has authored several articles published in international journals and organized and represented IPC at various national and international conferences and workshops. He has also participated in joint inspections for registration of manufacturing units and testing laboratories.</p>
</blockquote>
<blockquote>
<p><strong>Presenter</strong>: Mr. Praveen Arya (Application Engineer - GC/MS, Agilent Technologies)</p>
</blockquote>
<blockquote>
<p>Praveen Arya, Application Engineer at Agilent technologies, has a commitment and appreciation for Gas-phase residue applications. In 2005, Mr. Praveen Arya completed his M.Sc. in Food Technology . After post-graduation, he served as a Senior Analyst at SGS, Gurgaon- a commercial testing laboratory for 6 years and developed expertise in Residue analysis using sophisticated chromatographic instruments such as LCMS and GCMS. After that, in 2011, He joined Agilent Technologies as an Application Engineer where he supported country-wide GCMS customers for resolving application issues and method development. He has more than 18 years of experience in residue analysis in food and environmental samples using various high end chromatographic and spectrometric techniques (GC, GCMS, GCMS/MS, TDS, Headspace, Purge &amp; trap etc.). His area of specialization includes new analytical method development and validation as per national and international guidelines.</p>
</blockquote>


Agilent: Evolving Landscape on Control of Excipients Quality in Pharmaceutical Products

Evolving Landscape on Control of Excipients Quality in Pharmaceutical Products

PC, USP and Agilent experts share their views on the role of Pharmacopeia's in ensuring Quality of Pharmaceutical products and excipients

Control of Excipients Quality in Pharmaceutical Products

<p><strong>USP General Chapter &lt;621&gt; Chromatography is one of the most significant general chapters of USP-NF compendia, referenced in several components such as identity, assay, impurities and foreign substances, etc., of almost all its monographs.</strong></p>
<p>Establishing meaningful system suitability criteria for chromatography procedures are the key in obtaining reportable results used for compendial/regulatory compliance purpose. The chapter provides definitions for chromatographic attributes and parameters and the extent of adjustments in chromatographic conditions that can be done to the compendial procedures provided the system suitability criteria set and other performance characteristics are met.</p>
<p>In this webinar we will give an overview of General Chapter &lt;621&gt; Chromatography and the allowed adjustments to chromatographic conditions in the USP monographs based on the recent revisions of General Chapter &lt;621&gt;. Some case studies will be discussed.</p>
<blockquote>
<p><strong>Presenter</strong>: Manu Grover (Business Development Manager – Pharma Markets, Agilent Technologies, Inc.)</p>
</blockquote>
<blockquote>
<p>Manu Grover holds a postgraduate degree in Pharmacy from Manipal Academy, India. He has more than 21 years of chromatography experience and has worked in pharmaceuticals to support IND, NDA, and ANDA filings incompanies such as Dr. Reddy&#39;s, Panacea Biotec, and Ozone Pharmaceuticals. During his professional journey, he has developed and validated analytical methods on HPLC, GC, particle sizing, DSC, pXRD, and LC/MS instruments, as well as successfully filing multiple analytical dossiers in U.S./EU markets. In his current role, he works closely with the Agilent sales team, regulators, and pharmaceutical scientists. He shares market updates, trends, and expertise related tothe Agilent portfolio of columns and supplies.</p>
</blockquote>
<blockquote>
<p><strong>Presenter</strong>: Edmond Biba, Phd (Principal Scientist, USP)</p>
</blockquote>
<blockquote>
<p>Dr. Edmond Biba is a Principal Scientist in the General Chapters Department, Science Division, at the United States Pharmacopeial (USP) Convention. He is responsible for the development of several new USP-NF General Chapters, including a suite of chapters on Analytical Methodologies Based on Scattering Phenomena, Nitrosamine Impurities, and Image Analysis of Pharmaceutical Systems. These were produced with the USP volunteers and expert committee/expert panel members.</p>
</blockquote>
<blockquote>
<p>One of his responsibilities is maintaining a portfolio of USP-NF General Chapters. This includes keeping up-to-date scientific and regulatory content in these chapters by continuously reviewing and revising the chapters as needed, with the help of responsible USP expert committees or expert panels. Some representatives of the current chapters in the portfolio are: &lt;621&gt; Chromatography, &lt;197&gt; Spectroscopic Identification Tests, &lt;467&gt; Residual Solvents, &lt;1469&gt; Nitrosamine Impurities, &lt;429&gt; Light Diffraction Measurements of Particle Size, &lt;430&gt; Particle Size Analysis by Dynamic Light Scattering, &lt;432&gt; Determination of Zeta Potential by Electrophoretic Light Scattering, &lt;854&gt; Mid-Infrared Spectroscopy.</p>
</blockquote>
<blockquote>
<p>Dr. Biba received his Ph.D. in Synthetic Organic Chemistry from the American University, Washington DC, and a B.Sc. and M.Sc. in Chemical Engineering and Chemistry from the University of Tirana, Albania. Dr. Biba is member of Sigma Xi, the Scientific Research Honor Society, the American Chemical Society, and the American Association of Pharmaceutical Scientists. He is USP’s representative for ICH’s Residual Solvents Q3C (R9) and Mutagenic Impurities M7 (R2) working groups, and to the Product Quality Technical Committee (PQTC) of the Product Quality Research Institute (PQRI).</p>
</blockquote>


Agilent - Harmonized USP Chapter 621 Chromatography – Recent Revisions

Harmonized USP Chapter 621 Chromatography – Recent Revisions

An overview of General Chapter <621> Chromatography and the allowed adjustments to chromatographic conditions in the USP monographs

<p><strong>Are you ready to elevate your understanding of Nitrogen analysis by Gas Chromatography (GC)? Dive deep into the intricacies of N₂ analysis, gain valuable insights, and optimize your analytical processes for unparalleled precision.</strong></p>
<h4><strong>Webinar Highlights:</strong></h4>
<p><strong>1. Understanding the Importance of N₂ Analysis</strong></p>
<ul>
<li>Explore the significance of nitrogen analysis in various industries.</li>
<li>Learn how accurate N₂ measurements contribute to quality control and regulatory compliance.</li>
</ul>
<p><strong>2. Fundamentals of Gas Chromatography for N₂ Analysis</strong></p>
<ul>
<li>Delve into the basics of Gas Chromatography and its application in nitrogen analysis.</li>
<li>Gain insights into the key components and parameters for successful N₂ analysis.</li>
</ul>
<p><strong>3. Discover best practices for setting up and optimizing your GC system</strong></p>
<ul>
<li>Learn how to choose the right columns, detectors, and conditions.</li>
<li>Identify and overcome common issues encountered.</li>
<li>Get practical tips for troubleshooting to ensure accurate and reliable results.</li>
</ul>
<p><strong>4. Q&amp;A Session</strong></p>
<blockquote>
<p><strong>Presenter</strong>: Dr. Soma Dasgupta (Application Engineer GC/MS, Agilent Technologies)</p>
</blockquote>
<blockquote>
<p>With over 17 years of extensive experience in gas chromatography, Dr. Soma has explored diverse facets of this analytical technique, addressing inquiries across various sectors, from ensuring food safety to advancing pharmaceutical analyses. Her academic journey includes doctoral research at the University of Pune, where her focus was on developing comprehensive methods for analyzing agro-chemicals in fruits and vegetables.</p>
</blockquote>
<blockquote>
<p>Previously, having served as a Field Application Specialist for three years, she honed her expertise in the practical applications of gas chromatography. Since joining Agilent Technologies, she have been an integral part of a dynamic team dedicated to providing solutions that cater to our customers&#39; analytical needs. Her specialization encompasses multi-residue method development, with a specific focus on pesticides and environmental applications, as well as expertise in identifying genotoxic impurities in pharmaceuticals.</p>
</blockquote>
<blockquote>
<p>Throughout her career, She has contributed significantly to the field, with a portfolio of more than 25 publications, application notes, and a book chapter.</p>
</blockquote>


Agilent: Nitrogen (N₂) Analysis by Agilent GC

Nitrogen (N₂) Analysis by Agilent GC

Dive deep into the intricacies of N2 analysis, gain valuable insights, and optimize your analytical processes for unparalleled precision.

<p><strong>We just faced a new Helium shortage period which resulted in important price increase but also in supply issue.</strong></p>
<p>These critical events are becoming more and more frequent and if today there is no more issue with Helium delivery the price is still extremely high and will continue to increase. </p>
<p>In order to secure the lab from potential future shortage but also to reduce the analysis cost more and more analyst are switching to alternate carrier gas.</p>
<blockquote>
<p><strong>Presenter:</strong> Laurent Pascaud (Product Specialist GC &amp; GC/MS, Agilent)</p>
</blockquote>
<blockquote>
<p>After 10 years of experience within the French Anti-Doping Agency, Laurent Pascaud joined Agilent Technologies in 2007.</p>
</blockquote>
<blockquote>
<p>He now has over 15 years of analytical development expertise, first as an applications engineer and then as a GC and GCMS product specialist in various chemical markets.</p>
</blockquote>


Agilent - Tips & Tricks for a Smooth Transition from Helium to Alternate Carrier Gas

Tips & Tricks for a Smooth Transition from Helium to Alternate Carrier Gas

In order to secure the lab from potential future shortage but also to reduce the analysis cost more and more analyst are switching to alternate carrier gas.

Smooth Transition from Helium to Alternate Carrier Gas

<p><strong>In Gas chromatography 90% of trouble occurs in the injection system.</strong></p>
<p>In this troubleshooting session we will discuss the 10 most important maintenance points focusing on split/splitless injection systems. We will discuss the purpose and impact of the critical parts and setup used in split and splitless injection and how it impacts your results.  We will then cover installation, peak shape, contamination sources for sample and system, carrier gas, maintenance and life time using practical examples.</p>


Restek Corporation: Top 10 Maintenance Tips For Your GC Split/Splitless Injection System

Top 10 Maintenance Tips For Your GC Split/Splitless Injection System

In this troubleshooting session we will discuss the 10 most important maintenance points focusing on split/splitless injection systems.

Maintenance Tips For GC Split/Splitless Injection System

<h3><strong>PhenoAcademy Webinars - Gas Chromatography Series</strong></h3>
<h4><strong>Troubleshooting for Gas Chromatography</strong></h4>
<ul>
<li>Master how to recognize symptoms of challenges with method performance</li>
<li>Identify active sites and impurities within the column and system</li>
<li>Understand how to attribute common maintenance practices to specific remedies</li>
</ul>
<blockquote>
<p><strong>Presenter</strong>: Duilio Romanello (Senior Technical Specialist, Phenomenex)</p>
</blockquote>
<blockquote>
<p>Duilio Romanello graduated with his Bachelors of Science in Pharmaceutical Chemistry and Technology from University of Bologna. Duilio then joined Phenomenex in 2008 as an Inside Technical Sales Consultant becoming Team Leader in Italy for GC/SPE in 2010 and then for the Environmental &amp; Food Team.</p>
</blockquote>
<blockquote>
<p>Since 2016 he has been covering the role of  Account Manager for the South of Italy working remotely and acting as GC Specialist. Since November 2023 he is Senior Technical Specialist for the Technical team at Phenomenex.</p>
</blockquote>
<blockquote>
<p><strong>Presenter</strong>: Zachary Woodward (Senior Technical Specialist, Phenomenex)</p>
</blockquote>
<blockquote>
<p>Zachary Woodward is a Senior Technical Specialist with Phenomenex, Inc, assisting laboratories with method development in the bio-pharma, environmental, and food industries.  Zachary spent his formative years developing HPLC and GC methods with a pharmaceutical lab in Albany, NY, after which he developed HPLC and SPE methods in the clinical setting here in Southern California.  Zachary received his B.Sci. in Chemistry from the College of William and Mary, was awarded his Master’s in Chemistry at San Diego State University, and is happy to speak with you today!</p>
</blockquote>
<blockquote>
<p><strong>Presenter</strong>: Lucia Geis Asteggiante (Senior Technical Specialist, Phenomenex)</p>
</blockquote>
<blockquote>
<p>Lucia is a Senior Technical Specialist that has recently joined Phenomenex’s Global Technical Team. She has a broad experience in the field of Analytical Chemistry with a particular focus on LC chromatography coupled with mass spectrometry. Lucia comes from a strong academic and regulatory background with experiences ranging from method development and analysis of small molecules to large protein complexes. She gained her Ph.D. at the University of Maryland - College Park, USA and did her post-doctoral work at the University of Oxford, UK. During her time as a researcher, she has authored/co-authored 23 scientific publications and 2 book chapters.</p>
</blockquote>


Troubleshooting for Gas Chromatography

Recognize symptoms of challenges with method performance , identify active sites and impurities within the column and system

<p><span><strong>Purge &amp; Trap technology is often used to achieve the legal detection limits of volatile and very volatile organic compounds in water samples. Especially in case of water intended for human consumption, the regulatory requirements are particularly stringent. When dealing with more complex matrices, headspace analysis offers a much cleaner approach compared to purging the sample. However, sensitivity could be limited without a suitable enrichment of the analytes before injection.</strong></span></p><p><span>The technological developments in recent years on new headspace extraction/enrichment techniques, such as ITEX (In Tube Extraction), makes possible to achieve low detection limits for volatiles with a clean sampling approach, without purging. Different adsorbents can be used for ITEX depending on the analytical demand. Additionally, a suitable refocusing before transferring the sample into the chromatography column, provides narrow peaks, better signal-to-noise and enhanced sensitivity especially for very volatile organic compounds (VVOCs). This webinar gives an insight of the available technology along with various examples from a routine laboratory.</span></p><h5><span><strong>Who should attend:</strong></span></h5><ul><li><span>Laboratory manager of environmental testing laboratories</span></li><li><span>Analysts who have to detect trace levels of VOCs and VVOCs in water</span></li><li><span>Analysts looking for a clean and sensitive sampling techniques for VOCs and VVOCs in water</span></li></ul><blockquote><p><span><strong>Presenter:</strong> Daniela Cavagnino (Product Marketing Manager, GC &amp; Autosampler, Thermo Fisher Scientific)</span></p><p><span>Dr. Daniela Cavagnino received a Master Degree in Chemistry at the University of Milan, Italy. She started her career in gas chromatography at Thermo Fisher Scientific spending several years in the R&amp;D laboratories working on GC technology innovation and more than 15 years in product and marketing management roles promoting GC/GC-MS technology and applications.</span></p><p><span><strong>Presenter:</strong> Petra Gerhards (Regional Marketing Manager EMEA GC &amp; GC-MS, Thermo Fisher Scientific)</span></p><p><span>Petra Gerhards is a Regional Marketing Manager of GC and GC-MS at Thermo Fisher Scientific. She has more than 29 years of experience in the fields of GC-MS, SPE and LC-MS. Since joining the regional team, she has contributed to workflow solutions combining vials and closures with SPE solutions, GC-MS and LC-MS.</span></p></blockquote>

Thermo Scientific: Improvements for the analysis of VVOC using static and dynamic headspace

Improvements for the analysis of VVOC using static and dynamic headspace

Webinar on ITEX and headspace techniques for sensitive VOC and VVOC analysis in water, supporting regulatory compliance and routine environmental testing.

GCMS webinars focusing on GC - page 12

Improvements for the analysis of VVOC using static and dynamic headspace

Don’t Get Carried Away by Carryover: Troubleshooting GC Chromatography

Top 10 Maintenance Tips For Your GC Split/Splitless Injection System

Troubleshooting for Gas Chromatography

Tips & Tricks for a Smooth Transition from Helium to Alternate Carrier Gas

Navigating Troubled Waters: A Deep Dive into Water Injections by GC

Harmonized USP Chapter 621 Chromatography – Recent Revisions

Nitrogen (N₂) Analysis by Agilent GC

Evolving Landscape on Control of Excipients Quality in Pharmaceutical Products

Introduction to Gas Chromatography and Method Development

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