<p><strong>The quality of drinking water is under closer scrutiny than ever before. Beyond microbiological safety and major chemical contaminants, trace-level organic compounds increasingly determine whether water is perceived as clean, safe, and acceptable by consumers. Among these substances, volatile organic compounds (VOCs) play a central role — both from a regulatory and a sensory perspective.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_VOC_Analysis_in_Drinking_Water_Achieving_ppt_Level_Sensitivity_with_ITEX_Dynamic_Headspace_GC_MS_b4de2f994a.jpg" alt="Thermo Fisher Scientific: VOC Analysis in Drinking Water: Achieving ppt-Level Sensitivity with ITEX Dynamic Headspace GC-MS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_VOC_Analysis_in_Drinking_Water_Achieving_ppt_Level_Sensitivity_with_ITEX_Dynamic_Headspace_GC_MS_b4de2f994a.jpg 245w," sizes="100vw" width="1024" height="512"></p><p>Modern analytical laboratories face a dual challenge: complying with stringent legal requirements while simultaneously detecting compounds that are noticeable by humans at concentrations far below established health-based limits. This is particularly true for odor-active VOCs, where customer complaints may arise even when water is fully compliant.</p><h3><strong>What are VOCs — and why are they so challenging?</strong></h3><p>VOCs are a heterogeneous group of compounds defined primarily by their physical properties rather than their chemical structure. They typically exhibit:</p><ul><li>Low molecular weight</li><li>Relatively low boiling points (approximately 50–260 °C)</li><li>High vapor pressure</li><li>Low to moderate solubility in water</li></ul><p>This group includes substances such as <strong>light halogenated hydrocarbons (LHKW)</strong>, <strong>aromatic hydrocarbons (BTEX)</strong>, and <strong>trihalomethanes (THMs)</strong>, many of which are regulated in drinking water due to toxicological concerns or their role as disinfection by-products from an analytical standpoint, these same properties make VOCs difficult to quantify at ultra-trace levels. Losses during sample handling, insufficient enrichment, and water interference can all limit sensitivity — especially when target concentrations are in the low µg/L or ng/L range.</p><h3><strong>Regulatory pressure drives method sensitivity</strong></h3><p>European drinking water legislation defines not only maximum allowable concentrations but also strict performance criteria for analytical methods. <a target="_blank" rel="noopener noreferrer" href="https://eur-lex.europa.eu/eli/dir/2009/90/oj/eng?utm_source=chatgpt.com"><strong>Directive 2009/90/EC</strong></a> requires limits of quantification to be no higher than <strong>30% of the applicable environmental quality standard</strong>. For many VOCs, this translates directly into <strong>ppt-level analytical requirements</strong>.</p><p>As a result, laboratories must rely on techniques that go beyond conventional workflows while still maintaining robustness, reproducibility, and ease of use.</p><h3><strong>Headspace GC-MS: established — but not always sufficient</strong></h3><p>Headspace GC-MS remains a cornerstone of VOC analysis in water. <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/64"><strong>Static headspace</strong></a><strong> (SHS)</strong> methods are widely used due to their simplicity, cleanliness, and compatibility with routine laboratories. However, SHS relies on a single equilibrium extraction of the gas phase, which can limit sensitivity — particularly for very volatile compounds or analytes present at trace concentrations.</p><p>For these applications, additional enrichment steps are often required.</p><h3><strong>ITEX dynamic headspace: turning sampling into enrichment</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/order/catalog/product/1R77010-1125"><strong>ITEX (In-Tube Extraction) Dynamic Headspace</strong></a> bridges the gap between simplicity and sensitivity. Unlike static headspace, ITEX repeatedly draws defined volumes of headspace gas through an adsorbent trap, actively enriching analytes before injection into the GC system.</p><p><strong>This dynamic approach offers several decisive advantages:</strong></p><ul><li>True analyte enrichment directly from the headspace</li><li>Solvent-free sample preparation</li><li>Reduced risk of contamination and carryover due to a closed, syringe-based design</li><li>Straightforward maintenance with easy access to trap and syringe components</li></ul><p>By passing the headspace through the trap multiple times, ITEX effectively increases the sampled analyte mass without increasing sample volume — a key advantage for ppt-level analysis.</p><h3><strong>Tailored adsorbents for targeted performance</strong></h3><p><strong>ITEX performance can be optimized through the selection of appropriate adsorbent materials:</strong></p><ul><li><strong>Tenax TA</strong> for volatile and semi-volatile compounds</li><li><strong>Carbopack</strong> for hydrophobic analytes with minimized water displacement</li><li><strong>Carboxen and Carbosieve materials</strong> for very volatile compounds such as vinyl chloride</li></ul><p>This flexibility allows laboratories to adapt ITEX methods to a wide range of drinking water applications, from regulatory VOC panels to specialized odor investigations.</p><h3><strong>Managing water — without compromising sensitivity</strong></h3><p>Water is often the hidden enemy of trace VOC analysis. In ITEX, excess water can be efficiently removed by purging the trap with inert gas at low temperature before thermal desorption. The trap itself can then be heated to temperatures of up to <strong>350 °C</strong>, ensuring complete desorption of analytes while maintaining excellent repeatability.</p><p>Carryover testing demonstrated values of ≤0.027% for all analytes, even without blank subtraction — a critical requirement for trace analysis in regulated environments.</p><h3><strong>Chromatographic focusing for very volatile compounds</strong></h3><p>Highly volatile VOCs remain chromatographically challenging, even after enrichment. Combining ITEX with <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/gas-chromatography-gc/gc-systems/modules.html"><strong>PTV injection</strong></a><strong> and dedicated focusing liners</strong> significantly improves peak shape and signal-to-noise ratio. This double-focusing approach is especially effective for compounds such as vinyl chloride and other light halogenated hydrocarbons. When paired with <strong>SIM acquisition in </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/484"><strong>GC-MS</strong></a>, the result is robust, sensitive, and selective detection across a broad VOC range.</p><h3><strong>Taste and odor: why ppt really matters</strong></h3><p>One of the most demanding applications in drinking water analysis is the detection of odor-active compounds such as <strong>geosmin</strong>. Produced naturally by cyanobacteria and actinomycetes, geosmin causes an earthy, musty taste and odor that consumers can detect at concentrations as low as <strong>5–10 ng/L</strong>.</p><p>Although geosmin poses no health risk, even trace levels can trigger complaints and damage public trust. ITEX Dynamic Headspace GC-MS enables reliable detection well below the sensory threshold, supporting proactive water quality management rather than reactive troubleshooting.</p><h3><strong>Automation and flexibility for the modern laboratory</strong></h3><p>Drinking water laboratories often analyze a wide range of sample types and concentration levels. Automated platforms such as the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/422"><strong>TriPlus RSH SMART</strong></a><strong> autosampler</strong> support multiple injection and sampling techniques — including liquid injection, static headspace, SPME, and ITEX — with automatic tool change functionality.</p><p>Intelligent sequence control and consumable monitoring help laboratories maximize productivity while maintaining consistent analytical performance.</p><h3><strong>Conclusion: a future-proof approach to VOC analysis</strong></h3><p>ITEX Dynamic Headspace has proven to be a powerful and versatile alternative to purge-and-trap for the analysis of VOCs in drinking water. Its ability to deliver <strong>ppt-level sensitivity</strong>, combined with operational simplicity and excellent robustness, makes it ideally suited for both regulatory compliance and advanced odor analysis.</p><p>When integrated with PTV injection and SIM-based GC-MS detection, ITEX-DHS supports reliable quantification of even the most challenging VOCs — helping laboratories meet today’s requirements while preparing for tomorrow’s expectations</p><p><strong>Call to action</strong>:</p><p>To learn more about this interesting technology in a FREE webinar, register here:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5250532/C85F8F6AC85928EE5DB65E38D3C9B23F"><strong>April 23-Trinkwasserübewachung mit der ITEX</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5250534/258DDD452DE6AAA5FDEB0E72CBF70889"><strong>June 11th VOC Analytik in Trinkwasser mittels Headspace GC-MS und ITEX</strong></a></li></ul><h3><strong>Acknowledgement</strong></h3><p>I would like to thank <strong>Dr. Klaus Schrickel</strong>, Thermo Fisher Scientific Dreieich, Germany, for the contribution to this blog.</p><ul><li><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a>&nbsp;#GC #GC/MS # ITEX #Headspace</li></ul><blockquote><h5><strong>Petra Gerhards</strong></h5><p>Petra Gerhards, Dipl-Ing, is Regional Marketing Manager of GC and GC-MS for EMEA at Thermo Fisher Scientific. She has more than 29 years of experience in the fields of GC-MS, SPE and LC-MS. Since joining the regional team she has contributed to workflow solutions combining vials and closures with SPE solutions, GC-MS and LC-MS. She works with KOL's on data for regional specific marketing campaigns, organizes in-house seminars and works on customer specific solutions. Her main expertise is in the field of doping and drugs-of-abuse analysis.</p></blockquote>

VOC Analysis in Drinking Water: Achieving ppt-Level Sensitivity with ITEX Dynamic Headspace GC-MS

<p><strong>Visit the LabRulez booth at </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/871"><strong>analytica 2026</strong></a><strong> in Munich, 24. - 27. March 2026! You can find us in Hall A1, Booth A1.506. At the booth, you will be able to explore live demonstrations of how the LabRulez portals work and see selected analytical instruments from our pre-owned marketplace section.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg" alt="LabRulez at Analytica 2026: Hall A1 Floor Plan and Booth Location" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_Analytica_2026_Floor_plan_55e1057e03.jpg 245w," sizes="100vw" width="1516" height="881"></p><h3><strong>Would you like to learn how the LabRulez portals work?</strong></h3><p>➡︎ <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/"><strong>LabRulezLCMS</strong></a><br>➡︎ <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/"><strong>LabRulezGCMS</strong></a><br>➡︎ <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/"><strong>LabRulezICPMS</strong></a></p><ul><li>A <strong>unique online solution</strong> for <strong>your marketing</strong></li><li>A <strong>targeted audience</strong> from the <strong>analytical chemistry community</strong></li><li><strong>Modern technologies</strong> and a unique concept</li><li><strong>Design optimized for most smart devices</strong> – PC, mobile, and tablet</li><li><strong>Advanced statistical tools</strong> fully available to users</li></ul><h3><strong>Services Offered</strong></h3><h4><strong>News + Company Updates</strong></h4><ul><li>Publish <strong>news related to your instrumentation, applications, services, events, job openings</strong>, and more</li><li><strong>News is shared</strong> both on our <strong>portals</strong> and across our <strong>social media channels</strong></li></ul><h4><strong>Library – All Documents in One Place</strong></h4><ul><li><strong>Applications, posters, presentations, technical articles, brochures, specifications</strong></li><li><strong>Fas</strong>t and <strong>advanced search</strong> capabilities</li><li>Over <strong>32,000 documents</strong> currently available in our database</li></ul><h4><strong>Webinars</strong></h4><ul><li><strong>Upcoming and on-demand webinars</strong> from the field of analytical chemistry</li><li>More than <strong>5,500 webinars</strong> covering chromatography, mass spectrometry, and spectroscopy</li></ul><h4><strong>Careers</strong></h4><ul><li><strong>Targeted job</strong> listings in <strong>analytical chemistry</strong></li><li>Clear filtering by specialization or location</li><li><strong>Increased visibility for job postings</strong></li></ul><h4><strong>Companies</strong></h4><ul><li><strong>Company profile</strong> with key information and contacts</li><li><strong>Integration of all your activities on our portal:</strong> News, Library documents, Webinars, Upcoming Events, Careers, and mentions by partners or customers</li><li><strong>Connection to your Products </strong>listed on LabRulez portals</li></ul><h4><strong>Products and Services</strong></h4><ul><li>Comprehensive <strong>overview of instrumental techniques and services</strong></li><li>Targeting the analytical chemistry community and customers in the growing online environment</li></ul><h4><strong>Marketplace</strong></h4><ul><li><strong>Buying and selling pre-owned analytical equipment</strong></li><li>We purchase analytical instrumentation of all brands and ages</li><li><strong>Sell your equipment through LabRulez</strong></li><li>Request and purchase <strong>complete systems, modules</strong>, or <strong>spare parts</strong> with warranty and service</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg" alt="LabRulez at analytica 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_at_analytica_2026_bazar_7edf4a0872.jpg 88w," sizes="100vw" width="1600" height="2844"></p><h3><strong>What Will Be on Display at Our Booth?</strong></h3><p>Come and explore selected spare parts and modules from our marketplace section. These include both new, tested, and pre-owned items.</p><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar"><strong>LabRulezLCMS Marketplace</strong></a></h4><p><strong>Spare parts for LC/MS:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=378"><strong>Vacuum turbo pumps for LC/MS</strong></a></li></ul><p><strong>Spare parts for HPLC:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=397"><strong>Degassers for HPLC/UHPLC</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=368&amp;search=valve"><strong>Automatic valves for HPLC</strong></a></li><li>HPLC components for Agilent 1100, 1200, and 1260 Infinity II series</li></ul><p><strong>Consumables:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=377"><strong>HPLC lamps</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/bazaar?category=48"><strong>HPLC columns</strong></a></li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar"><strong>LabRulezGCMS Marketplace</strong></a></h4><p><strong>Spare parts for GC/MS:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=367&amp;search=turbo"><strong>Turbo pumps for GC/MS</strong></a></li></ul><p><strong>Spare parts for GC:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=366&amp;search=EPC"><strong>EPC modules</strong></a></li></ul><p><strong>Sample injection</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar/432"><strong>Autosampler 7693A for GC</strong></a></li></ul><p><strong>Consumables:</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/bazaar?category=7"><strong>GC columns </strong></a>and selected accessories</li></ul>

LabRulez at analytica 2026

<h4><strong>The future of chromatography is here – are you ready?</strong></h4><p><strong>Chromatography continues to evolve at an unprecedented pace, driven by the need for sustainability, analytical performance, and digital innovation. This dedicated analytica 2026 conference session brings together leading experts to explore how next-generation GC and LC technologies, advanced hyphenated techniques, microfluidics, additive manufacturing, and data-driven workflows are reshaping analytical science. From greener HPLC strategies and supercritical fluid chromatography to ion mobility–HRMS and multidimensional separations, the programme provides a forward-looking perspective on how laboratories can adapt to emerging analytical challenges and unlock new scientific insights.</strong></p><blockquote><h5><strong>Companies participating in the analytica 2026 trade fair:</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1200"><strong>Agilent Technologies</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1206"><strong>ANALYTIKA</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1197"><strong>Bruker</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1201"><strong>DataApex</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1195"><strong>KNAUER</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/7049"><strong>LabRulez</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/1227"><strong>LECO</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/1202"><strong>Markes International</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1214"><strong>Metrohm</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1213"><strong>PerkinElmer</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/1216"><strong>Restek</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1196"><strong>SCIEX</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1230"><strong>SciY</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1215"><strong>Shimadzu</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1191"><strong>Thermo Fisher Scientific</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/events/1217"><strong>Wasson-ECE</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/1228"><strong>Waters Corporation</strong></a></li></ul></blockquote><h4><strong>Programme Tuesday, 24 March 2026, ICM Saal 5</strong></h4><h5><strong>09:30 - 10:00 EuChemS-DAC Tribute to Prof. Dr. Wolfgang Buchberger presented by Dr. Martin Vogel</strong></h5><ul><li>Dr. Martin Vogel | Germany | University of Münster</li></ul><h4><strong>The Future of Chromatography Is Here – Are You Ready? Towards Sustainable HPLC: Are Narrower Columns the Solution? (GDCh)</strong></h4><h5><strong>10:00 - 10:30 From filament to chromatogram: using additive manufacturing to democratise miniaturisation and promote sustainability in analytical laboratories</strong></h5><ul><li>Dr. Thorsten Teutenberg | Germany | Institut für Umwelt &amp; Energie, Technik &amp; Analytik e.V. (IUTA)</li></ul><h5><strong>10:30 - 11:00 Supercritical fluid chromatography as a sustainable analytical method</strong></h5><ul><li>Prof. Dr. Caroline West | France | University of Orleans</li></ul><h5><strong>11:00 - 11:30 Microfluidic versus conventional LC–HRMS for HIV metabolomics: a comparative performance assessment</strong></h5><ul><li>Frederic Lynen | Belgium</li></ul><h5><strong>11:30 - 12:30 Poster Session sponsored by Shimadzu</strong></h5><h4><strong>The Future of Chromatography Is Here – Are You Ready? GC &amp; HPLC: The Cutting-Edge Advances You Need to Know - Part I (GDCh)</strong></h4><h5><strong>12:30 - 13:00 Next-Gen HPLC: A Column Technology Deep Dive</strong></h5><ul><li>Prof. Dr. Gert Desmet | Belgium | Free University Brussels</li></ul><h5><strong>13:00 - 13:30 GC-Based hyphenated techniques for detailed characterization of complex samples</strong></h5><ul><li>Prof. Dr. Giorgia Purcaro | Belgium | University of Liège</li></ul><h5><strong>13:30 - 14:00 Molecular Encoding as a Tool to Enable Data Science-Assisted Analytical Measurements</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Kevin+Schug"><strong>Prof. Kevin Schug</strong></a> | USA | The University of Texas at Arlington</li></ul><h5><strong>14:00 - 14:30 Good Resolutions for Bad Pollutants: Ion Mobility–HRMS to Resolve Complex Environmental Mixtures</strong></h5><ul><li>Prof. Dr. Gauthier Eppe | Belgium</li></ul><h4><strong>The Future of Chromatography Is Here – Are You Ready? GC &amp; HPLC: The Cutting-Edge Advances You Need to Know - Part II (GDCh)</strong></h4><h5><strong>15:00 - 15:30 GC×GC-TOFMS for Medical Volatolomics</strong></h5><ul><li>Prof. Dr. Jean-François Focant | Belgium | University of Liege</li></ul><h5><strong>15:30 - 16:00 Cryogenic band compression as a means to simplify the sample preparation step in 1D and comprehensive 2D GC food analysis</strong></h5><ul><li>Prof. Dr. Peter Q. Tranchida | Italy | University of Messina</li></ul><h5><strong>16:00 - 16:30 Significance of radial dispersion to effective modulation in two-dimensional liquid chromatography and its role in machine-learning based automated method development</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=bob+pirok"><strong>Bob Pirok</strong></a> | Netherlands | University of Amsterdam</li></ul><h5><strong>16:30 - 17:00 LCxSFC coupling: A robust tool to aid understanding of renewable and circular industrial processes&nbsp;</strong></h5><ul><li>Karine Faure | France | University of Lyon</li></ul>

Analytica 2026: The Future of Chromatography Is Here – Are You Ready?

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Thermo Scientific™ TSQ™ 9000 GC-MS/MS System

Triple quadrupole GC-MS/MS system offering exceptional sensitivity, robustness, and smart automation for trace-level quantitation in food, environmental, and forensic analysis.

<p><strong>High-performance triple quadrupole GC-MS/MS platform for routine trace-level quantitation in complex matrices</strong></p><p>The <strong>TSQ™ 9000 GC-MS/MS system</strong> is built for laboratories that demand <strong>uncompromising sensitivity, throughput, and robustness</strong> for trace-level analysis in <strong>food safety, environmental, and forensic/toxicology applications</strong>. Designed to increase productivity and reduce cost-per-sample, this system delivers best-in-class performance with intuitive tools for routine and advanced users alike.</p><h3><strong>Key features and benefits</strong></h3><h4>🚀 <strong>Unstoppable Sensitivity</strong></h4><ul><li><strong>Advanced Electron Ionization (AEI)</strong> source for attogram-level sensitivity, ideal for demanding applications like dioxins and pesticides in baby food.</li><li><strong>ExtractaBrite™ ion source</strong>: robust EI/CI performance, proven in routine use; fully removable under vacuum with NeverVent™.</li><li><strong>Ionization modes: </strong>EI, PCI, NCI (CI available with ExtractaBrite only)</li></ul><h4>🔬 <strong>Unstoppable Performance</strong></h4><ul><li><strong>EvoCell™ collision cell</strong>: up to 800 SRM transitions/s with excellent precision</li><li><strong>0.5 ms minimum dwell time</strong>; up to 97 scans/s; 20,000 u/s quadrupole scan speed</li><li><strong>Mass range</strong>: 1.2–1100 u, unit mass resolution</li><li><strong>Mass stability</strong>: &lt;0.1 u over 48 h</li></ul><h4>🔧 <strong>Unstoppable Uptime</strong></h4><ul><li><strong>NeverVent™ technology</strong> (with VPI &amp; ExtractaBrite): perform maintenance or column changes without venting</li><li><strong>V-Lock</strong> column isolation prevents system venting during GC maintenance</li><li><strong>Dual heated source lenses</strong> for minimal contamination and high matrix tolerance</li></ul><h3><strong>Ease of Use and Intelligent Method Development</strong></h3><ul><li><strong>AutoSRM™</strong>: Automated SRM development wizard</li><li><strong>SIM Bridge™</strong>: Convert legacy SIM methods into SRM in seconds</li><li><strong>Timed-SRM and Retention Time Alignment (RTA)</strong>: Maintain optimal sensitivity and peak tracking across injections</li><li><strong>SmartTune™</strong>: Intuitive system tuning with error guidance</li></ul><h3><strong>Software Platforms</strong></h3><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Chromeleon™ CDS</strong></a></h4><ul><li>Fully integrated control of chromatography and mass spectrometry</li><li>One-click eWorkflows™, Intelligent Run Control, automated compliance tools</li><li>Environmental Analysis Extension Pack for U.S. EPA workflows</li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/77"><strong>TraceFinder™</strong></a></h4><ul><li>Comprehensive solution for method development, acquisition, processing, and reporting</li><li>Preloaded SRM database for over 1300 pesticides (environmental/food safety versions)</li><li>Application-specific variants for <strong>clinical research</strong>, <strong>toxicology</strong>, and <strong>environmental labs</strong></li></ul><h3><strong>System Specifications</strong></h3><ul><li><strong>Ion sources</strong>: AEI and ExtractaBrite (CI optional)</li><li><strong>Transfer line temperature</strong>: up to 400 °C</li><li><strong>Detector</strong>: DynaMax™ XR system with off-axis dynode and wide dynamic range (&gt;10⁷)</li><li><strong>Mass resolution</strong>: Adjustable 0.4–2.5 u, preset or manual</li><li><strong>Pumping system</strong>: High-capacity turbomolecular with rotary vane or optional oil-free scroll</li><li><strong>Direct Probe Options (VPI only)</strong>: DIP and DEP probes for solid and rapid samples</li></ul><h3><strong>Sample Introduction Options</strong></h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/68"><strong>AI/AS 1310 Autosampler</strong></a>: high-precision injections, advanced rinse protocols</li><li><strong>TriPlus™ RSH Autosampler</strong>: robotic automation including dilution, internal standard addition, derivatization, and tool switching</li></ul><h3><strong>System Dimensions and Compatibility</strong></h3><ul><li>Fully compatible with <strong>Thermo Scientific™ TRACE™ 1300/1310 GC</strong></li><li><strong>Mass spectrometer</strong>: 44 × 40 × 89 cm; 61 kg</li><li>Modular design enables scalable performance and easy upgrades</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/application::product.product/Thermo-TSQtm-9000-1310-triplus-rsh_l.webp" alt="Thermo Scientific™ TSQ™ 9000 GC-MS/MS System" width="708" height="708"></p>

Thermo Scientific TSQ 9610 Triple Quadrupole GC-MS

The Thermo Scientific TSQ 9610 triple quadrupole GC-MS/MS systems is the best-in-class system for ultimate sensitivity and quantitation of targeted compounds. Optimized for high-throughput analytical laboratories.

<div><div id="product-description"><p><strong>To confidently stay ahead, your GC-MS/MS system must deliver ultimate performance while consistently producing trusted quantitative results. For this, turn to the Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System. User-centric Thermo Scientific™ NeverVent™ technology, extended-life detector, and intelligent software eliminate unnecessary downtime to maximize your sample throughput and return on investment (ROI). New extended linear dynamic range combined with proven high sensitivity ensures you keep ahead of the toughest regulatory methods and business demands.</strong></p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/mass-spectrometry/gas-chromatography-mass-spectrometry-gc-ms/gc-ms-systems/triple-quadrupole-gc-ms.html"><strong>Discover TSQ 9610 GC-MS highlights</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/store/instruments/configurators/trace1600"><strong>Build your GC-MS system</strong></a></li></ul></div><div><h4><strong>Increase instrument uptime</strong></h4><p>Eliminate unnecessary, unplanned instrument downtime to deliver high-confidence quantitative results, day after day. The TSQ 9610 Triple Quadrupole GC-MS/MS System combines unstoppable robustness with the ability to change the GC column and clean the ion source without interrupting analytical workflows.<br><br>Monitor key aspects of your GC-MS system. With Thermo Scientific™ SmartStatus™ instrument tracking within Chromeleon CDS, quickly see whether instruments are ready to run samples, if maintenance is required or if consumables should be replaced. The fully customizable software enables you to make data-driven decisions on when to perform maintenance and avoid unnecessary downtime.</p><h4><strong>Maximize sample throughput</strong></h4><p>When high sample throughput is essential, the system delivers results on time and with ease. Automated workflows and simplified operation ensure every user produces consistent results, sample after sample. Extended linear range and rapid selected reaction monitoring (SRM) scanning enable method consolidation so you can analyze more compounds in a single run. When these capabilities are combined with best-in-class uptime and sensitivity, you stay ahead of any productivity demand.</p><h4><strong>Realize rapid return on investment&nbsp;</strong></h4><p>Ensuring your system delivers results as soon as it’s installed is necessary to achieve rapid ROI. With built-in intelligence that simplifies instrument setup, analytical methods, and everyday operation, the TSQ 9610 Triple Quadrupole GC-MS/MS System is designed for accelerated deployment. Reduced needs for operator training and faster time to full productivity together with maximum sample throughput provide fast return on your instrument</p><h3><strong>TSQ 9610 GC-MS/MS highlights</strong></h3><h4><strong>Unstoppable confidence in quantitative performance</strong></h4><p>Delivering attogram-level sensitivity and best-in-class selected reaction monitoring (SRM) performance, the TSQ 9610 GC‑MS/MS system consistently meets required detection limits as you run samples. Choose the rugged Thermo Scientific ExtractaBrite ion source or the ultra-sensitive, ultra-robust Thermo Scientific Advanced Electron Ionization (AEI) ion source, depending on your sensitivity needs.</p><p>The XLXR electron multiplier detector which extends dynamic range twofold compared to the previous design. Extended dynamic range capability enables labs to combine methods, including calibration curve development, allowing analysis of low- and high-concentration compounds in a single run.</p><div container-id="cq-colctrl-lt0" comp-id="A2"><div><h4><strong>Unstoppable confidence in uptime for full-time productivity</strong></h4><p>The TSQ 9610 GC-MS/MS system is specifically designed for complex sample matrices in high-throughput applications.&nbsp;Using NeverVent technology with the Vacuum Probe Interlock (VPI) and V-Lock source plug, planned maintenance such as changing column and ion source cleaning can be performed without venting the mass spectrometer, increasing uptime. NeverVent technology is available on both the Thermo Scientific ExtractaBrite and the Thermo Scientific NeverVent Advanced Electron Ionization (NV-AEI) sources.</p></div></div><div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><h4><strong>Unstoppable confidence in your investment</strong></h4><p>Rapid instrument deployment reduces time to results and revenue generation. That’s why the TSQ 9610 Triple Quadrupole GC-MS/MS System includes a comprehensive set of automated tools to provide users with a seamless experience when transitioning from other platforms, developing methods, and analyzing samples. This built-in intelligence reduces operator training needs and time to full productivity for rapid ROI.</p></div></div></div><h4><strong>Unstoppable confidence in sample throughput</strong></h4><p>Maximizing sample throughput is essential to producing results on time. The TSQ 9610 Triple Quadrupole GC-MS/MS System incorporates user-centric innovations that extend service intervals, reduce maintenance, and allow methods consolidation to boost sample throughput while maintaining certainty in quality of results.</p></div></div>

Waters Xevo TQ-GC Mass Spectrometry System

The Xevo TQ-GC allows routine quantitation of multiple contaminants in matrix sample. The consistent high performance allows regulatory limits to be comfortably passed reducing the need for frequent user intervention and re-optimization.

<div><div><h4><strong>The perfect addition to your laboratory</strong></h4></div></div><div><div><p><strong>Demands to meet regulations are increasing pressure on laboratories, and in order to meet these challenges laboratories must develop and run methods that provide high-quality, consistent results, day in and day out.&nbsp;</strong></p><div><div><div><div><p>The <strong>Xevo TQ-GC</strong> is a robust <strong>Electron Ionization (EI) and Chemical Ionization (CI)</strong> Gas Chromatography (GC)-MS/MS platform that allows <strong>routine quantification of multiple contaminants in complex matrices</strong>. The <strong>Xevo TQ-GC</strong> consistently <strong>surpasses the sensitivity required to meet regulatory limits</strong>, thus reducing the need for frequent user intervention and re-optimization. In addition, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/635"><strong>MassLynx Software </strong></a><strong>security</strong> controls user access, giving you more control to assist with laboratory compliance.</p><p>Laboratories can also <strong>develop methods rapidly using Quanpedia</strong>, which allows fast response to changes in legislative demands and for customized methods. All the speed, sensitivity, and reliability you have come to expect from Xevo now with GC-MS/MS.</p><ul><li><strong>Reduce training time and costs</strong> with a single software workflow for GC-MS/MS and LC-MS/MS analysis</li><li><strong>Achieve comprehensive application coverage</strong> powered by Quanpedia database driven workflow</li><li><strong>Easily surpass regulatory limits</strong> with fit-for-purpose performance in difficult matrices</li><li><strong>Choose from a wide range of injection modes</strong>, including liquid, headspace, and solid phase microextraction (SPME) analysis</li><li><strong>Control access to the GC-MS system</strong> to meet regulatory requirements with MassLynx security</li><li><strong>Simplify maintenance tasks</strong> with a rapid and mistake-proof source design</li></ul></div></div><div><div><h4><strong>Recommended Use</strong></h4><p>For routine quantitation of multiple contaminants in an extracted matrix sample.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_4_fda01dffa7.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_4_fda01dffa7.jpg 245w," sizes="100vw" width="1024" height="606"></p><div><div><h3><strong>Maximize uptime to ensure your success</strong></h3><p>Ensuring you achieve <strong>reliable and predictable results</strong> is at the heart of the design of the Xevo TQ-GC. The system has been rigorously tested to ensure that you <strong>spend less time on routine maintenance</strong>, and that it can be scheduled to fit around the laboratory workload, <strong>maximizing uptime</strong> and <strong>minimizing disruption</strong>.</p><p>To ensure you don’t spend your precious time on lengthy instrument setup, <strong>Intellistart health check</strong> informs you whether the system is ready to run injections and, if not, how the situation can be remedied. Your lab only needs <strong>minimal tools for instrument maintenance</strong>, and if any maintenance is needed, it is <strong>fast and mistake-proof</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_5_ebae58fe9d.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Repeatability from replicate (n=200) injection of grape extract containing five pesticides at 0.01 mg/kg." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_5_ebae58fe9d.jpg 245w," sizes="100vw" width="1024" height="541"></p></div></div><div><div><h3><strong>Achieve efficiency and flexibility</strong></h3><p>In a busy analytical lab, time is precious, especially when demands change regularly and the requirement for shorter turnaround times is increasing. With <strong>Quanpedia</strong>, you can easily deal with a wide variety of sample matrices, target analytes and gas chromatography (GC) conditions. The <strong>fully customizable database</strong> means that you no longer need to be concerned about having the flexibility to adapt to changes in regulations, as it contains compound classes that are most relevant to regulations, and modifications to existing methods are quick and simple. You can reduce your method development time by including automatic scheduling of multiple reaction monitoring (MRM) transitions that account for any shift in retention times that occur because of column maintenance.</p><p>You can also <strong>shorten turnaround times</strong> by <strong>increasing the number of components in a single analytical run</strong>, which is enabled by <strong>acquisition rates of up to 500 MRM/sec</strong> with no significant degradation in performance. This means more MRM transitions can be added to a run while still achieving high quality results.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_caab24f949.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Generation of GC-MS acquisition and processing methods is performed automatically." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_caab24f949.jpg 245w," sizes="100vw" width="1024" height="546"></p></div></div><div><div><h3><strong>Capture the whole picture in targeted analyses</strong></h3><p>Reduce the risks to method performance and data quality associated with undetected interferences and unexpected compounds when conducting targeted analysis. <strong>RADAR improves method development and aids troubleshooting</strong> with the ability to detect and confirm analytes not specifically targeted through NIST library confirmation and routinely characterize unexpected contaminants. With this additional information, you can be completely confident in your data and avoid additional confirmatory analyses.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_2_48915d33e6.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Use of RADAR and NIST library search to identify a co-extracted compound in green tea matrix." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_2_48915d33e6.jpg 245w," sizes="100vw" width="1024" height="286"></p></div></div><div><div><h3><strong>Confidently meet regulatory demands</strong></h3><p>To ensure confidence in results, most analysts would prefer to operate comfortably below regulatory limits. You can achieve this confidence with Xevo TQ-GC, not only through <strong>reliable high performance</strong> but also as a result of <strong>TargetLynx</strong>, an Application Manager common across Waters LC and GC platforms. This means it not only gives full analyte quantification, simplified review of results, and customizable reporting, but also provides a common platform between instrument types simplifying data processing and reducing time to results.</p><p>With <strong>Waters MassLynx Basic Security</strong>, you are in control. Ideal for laboratories who need to manage or control access to a GC-MS system. MassLynx Basic Security contains an events audit log for added traceability for audits and accreditation, and the security can also be used with TargetLynx acquisition software.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Xevo_TQ_GC_Mass_Spectrometry_System_3_a0c5238bfe.jpg" alt="Waters Xevo TQ-GC Mass Spectrometry System: Comprehensive and streamlined results review with TargetLynx flags any results outside user-defined tolerances." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Xevo_TQ_GC_Mass_Spectrometry_System_3_a0c5238bfe.jpg 245w," sizes="100vw" width="1024" height="499"></p></div></div></div></div></div></div></div></div>

Products from category Triple quadrupoles focused on GC/MSD - page 1

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