Thermo Scientific™ TSQ™ 9000 GC-MS/MS System

High-performance triple quadrupole GC-MS/MS platform for routine trace-level quantitation in complex matrices

The TSQ™ 9000 GC-MS/MS system is built for laboratories that demand uncompromising sensitivity, throughput, and robustness for trace-level analysis in food safety, environmental, and forensic/toxicology applications. Designed to increase productivity and reduce cost-per-sample, this system delivers best-in-class performance with intuitive tools for routine and advanced users alike.

Key features and benefits

🚀 Unstoppable Sensitivity

• Advanced Electron Ionization (AEI) source for attogram-level sensitivity, ideal for demanding applications like dioxins and pesticides in baby food.
• ExtractaBrite™ ion source: robust EI/CI performance, proven in routine use; fully removable under vacuum with NeverVent™.
• Ionization modes: EI, PCI, NCI (CI available with ExtractaBrite only)

🔬 Unstoppable Performance

• EvoCell™ collision cell: up to 800 SRM transitions/s with excellent precision
• 0.5 ms minimum dwell time; up to 97 scans/s; 20,000 u/s quadrupole scan speed
• Mass range: 1.2–1100 u, unit mass resolution
• Mass stability: <0.1 u over 48 h

🔧 Unstoppable Uptime

• NeverVent™ technology (with VPI & ExtractaBrite): perform maintenance or column changes without venting
• V-Lock column isolation prevents system venting during GC maintenance
• Dual heated source lenses for minimal contamination and high matrix tolerance

Ease of Use and Intelligent Method Development

• AutoSRM™: Automated SRM development wizard
• SIM Bridge™: Convert legacy SIM methods into SRM in seconds
• Timed-SRM and Retention Time Alignment (RTA): Maintain optimal sensitivity and peak tracking across injections
• SmartTune™: Intuitive system tuning with error guidance

Software Platforms

Chromeleon™ CDS

• Fully integrated control of chromatography and mass spectrometry
• One-click eWorkflows™, Intelligent Run Control, automated compliance tools
• Environmental Analysis Extension Pack for U.S. EPA workflows

TraceFinder™

• Comprehensive solution for method development, acquisition, processing, and reporting
• Preloaded SRM database for over 1300 pesticides (environmental/food safety versions)
• Application-specific variants for clinical research, toxicology, and environmental labs

System Specifications

• Ion sources: AEI and ExtractaBrite (CI optional)
• Transfer line temperature: up to 400 °C
• Detector: DynaMax™ XR system with off-axis dynode and wide dynamic range (>10⁷)
• Mass resolution: Adjustable 0.4–2.5 u, preset or manual
• Pumping system: High-capacity turbomolecular with rotary vane or optional oil-free scroll
• Direct Probe Options (VPI only): DIP and DEP probes for solid and rapid samples

Sample Introduction Options

• AI/AS 1310 Autosampler: high-precision injections, advanced rinse protocols
• TriPlus™ RSH Autosampler: robotic automation including dilution, internal standard addition, derivatization, and tool switching

System Dimensions and Compatibility

• Fully compatible with Thermo Scientific™ TRACE™ 1300/1310 GC
• Mass spectrometer: 44 × 40 × 89 cm; 61 kg
• Modular design enables scalable performance and easy upgrades

Thermo Scientific™ TSQ™ 9000 GC-MS/MS System