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Quantification of Nitrosamine Impurities in Metformin Using Agilent GC/MS/MS Instrumentation

 

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Nitrosamine Impurities Application Guide Confidently Detect and Quantify Mutagenic Impurities in APIs and Drug Products Sartan-Based Losartan Valsartan Candesartan Telmisartan Metformin Ranitidine Nitrosamines are formed by chemical reactions that occur during API manufacturing whether from starting materials, intermediates, reactants, reuse…
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Application Note Pharma & Biopharma Analysis of Five Nitrosamine Impurities in Drug Products and Drug Substances Using Agilent GC/MS/MS Instrumentation Authors Soma Dasgupta, Lalith Hansoge, Vivek Dhyani, Samir Vyas, and Melissa Churley Agilent Technologies, Inc. Abstract This application note highlights…
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Nitrosamines Analysis in Pharmaceuticals Using Single Quadrupole GC/MS or Triple Quadrupole GC/MS Consumables workflow ordering guide R1 N N R2 R O 2 R 1 R N N 2 R 1 R O R 2 1 N N N N…
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CASE STUDY 73263 Overcoming the challenges of nitrosamine impurities in drugs What pharmaceutical QA/QC laboratories need to know: Advanced GC-MS capabilities for cGMP nitrosamine testing Why we need to analyze nitrosamine impurities in drugs Unacceptable levels of nitrosamine impurities were…
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