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Analysis of Five Nitrosamine Impurities in Drug Products and Drug Substances Using Agilent GC/MS/MS Instrumentation

Applications | 2020 | Agilent TechnologiesInstrumentation
GC/MSD, GC/MS/MS, GC/QQQ
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
Key words
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Application Note Pharma and Biopharma Quantification of Nitrosamine Impurities in Metformin Using Agilent GC/MS/MS Instrumentation Authors Soma Dasgupta, Vivek Dhyani, Samir Vyas, and Melissa Churley, Agilent Technologies, Inc. Abstract Since June 2018, several drugs were recalled due to the presence…
Key words
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Nitrosamine Impurities Application Guide Confidently Detect and Quantify Mutagenic Impurities in APIs and Drug Products Sartan-Based Losartan Valsartan Candesartan Telmisartan Metformin Ranitidine Nitrosamines are formed by chemical reactions that occur during API manufacturing whether from starting materials, intermediates, reactants, reuse…
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Nitrosamines Analysis in Pharmaceuticals Using Single Quadrupole GC/MS or Triple Quadrupole GC/MS Consumables workflow ordering guide R1 N N R2 R O 2 R 1 R N N 2 R 1 R O R 2 1 N N N N…
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Application Note Pharma & Biopharma Screening of Nitrosamine Impurities in Drug Products and Drug Substances Using Agilent GC/MS/MS Instrumentation Authors Abstract Carole Antoine, Milan Macé, Elodie Barrau, and Emmanuel Desmartin Eurofins Amatsi Analytics This application note highlights a comprehensive solution…
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