Overcoming the challenges of nitrosamine impurities in drugs
Technical notes | 2020 | Thermo Fisher ScientificInstrumentation
GC/MSD, GC/MS/MS, HeadSpace, GC/SQ, GC/QQQ
IndustriesPharma & Biopharma
ManufacturerThermo Fisher Scientific
Key wordsmin, ndma, ndea, nitrosamine, neipa, time, temperature, impurities, orbitrap, aquisition, mass, source, exactive, loop, kpa, injection, ppm, sim, hold, nitrosamines, ion, mode, vial, counts, aei, extractabrite, compound, headspace, pressure, thermo, electron, incubation, msx, purge, spiked, pharmaceutical, coupled, ionization, energy, autosampler, scientific, technology, nevervent, ndipa, xylene, metformin, cycles, equilibration, washing, accuracy
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Overcoming the challenges of nitrosamine impurities in drugs
2020|Thermo Fisher Scientific|Others
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Application note | 001561 Pharma Determination of 18 nitrosamine impurities in sartan drug products using gas chromatography coupled with high-resolution Orbitrap mass spectrometry (GC-HRMS) Authors Goal Arnab Goon, Aarti Karkhanis, 1 The aim of this study is to develop a…
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