We are pleased to announce that a maintenance release is now available for KnowItAll 2026. Maintenance releases are an important way to introduce improvements and bug fixes between major releases to make sure users get the most out of KnowItAll.In Fall 2025, we announced the KnowItAll 2026 major release featuring a new principal component analysis tool, Trendfinder, and various advances for spectral analysis workflows. This is the first update available after that release.<h5>Updates in the 2026.1 maintenance release include:</h5><ul><li>Continued to LC-MS deconvolution improvement</li><li>Updated the DEA regulations rulebase that’s used to automatically categorize structures in databases you build in MineIt according to current Drug Enforcement Agency controlled substance regulations.</li><li>Various bug fixes</li></ul>We encourage users to update now to the most recent version of the software to ensure the best performance.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://get.knowitall.com/Download?_gl=1*18h0vjr*_gcl_au*Mjk3ODY0Mzg1LjE3MTMyNzcyMDEuMTkwNDkyNDI4NS4xNzEzMzY3NDc0LjE3MTMzNjc0Nzk.">Download the most recent version here</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/whats-new-in-knowitall-2026/">What's New in KnowItAll 2026</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/knowitall-version-history/">KnowItAll version history</a></li></ul><h4>About KnowItAll</h4>KnowItAll Software offers solutions to analyze and manage multiple types of spectral and chemical data in multiple file and instrument formats. KnowItAll's integrated toolsets eliminate the need for multiple software packages and increase overall lab efficiency and staff proficiency. Combined with Wiley’s comprehensive, high-quality spectral reference libraries, it provides an unparalleled solution for fast, reliable spectral analysis. Learn more.<h4>About <a target="_blank" rel="noopener noreferrer" href="https://www.wiley.com/en-ie/">Wiley</a></h4>Wiley (NYSE: WLY) is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning. Visit us at Wiley.com and Investors.Wiley.com. Follow us on Facebook, X, LinkedIn and Instagram.

KnowItAll 2026.1 maintenance release now available - Upgrade for the latest features and fixes

Industrial laboratories have some of the most demanding analytical environments in the world. Whether monitoring refinery processes, ensuring product purity in petrochemical plants, or supporting quality control in chemical manufacturing, these labs rely on gas chromatography (GC) every hour of every day. Uptime, reproducibility, and serviceability are not “nice to haves” — they are mission-critical.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_A_Better_Path_for_Industrial_GC_Users_How_the_TRACE_1600_Series_GC_Delivers_Reliability_Innovation_and_Seamless_Open_Lab_CDS_Integration_613341c463.jpeg" alt="Thermo Fisher Scientific: A Better Path for Industrial GC Users — How the TRACE 1600 Series GC Delivers Reliability, Innovation, and Seamless OpenLab CDS Integration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_A_Better_Path_for_Industrial_GC_Users_How_the_TRACE_1600_Series_GC_Delivers_Reliability_Innovation_and_Seamless_Open_Lab_CDS_Integration_613341c463.jpeg 245w," sizes="100vw" width="1024" height="512">Frequent hardware failures, diminishing vendor responsiveness, and limited innovation may create pressure points for many labs already operating under lean staffing and nonstop production demands. However, the most common reason industrial labs hesitate to evaluate alternative GC systems is not hardware-related — it’s software-related. One perceived obstacle often holds them back: We can’t change our CDS!This hesitation makes perfect sense. Industrial labs often run anywhere from a dozen to fifty or more GCs in a familiar and well-integrated software environment. Every method is validated in it. Every QA and data integrity process depends on it. These labs run lean, often 24/7, and they simply don’t have the time, or the appetite, for a software migration. Even the idea of retraining operators is enough to stop the discussion before it starts.<h3>The industrial GC market is ready for change</h3>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/483">Thermo Scientific TRACE 1600 Series GC</a> and the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/487">Thermo Scientific AI/AS 1610 autosampler</a>, including the high-throughput dual-channel Gemini configuration, have been recently fully integrated into one of the most popular chromatography data systems in the industrial laboratories, Agilent OpenLab CDS.&nbsp;With the new SII 1.3 driver the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/483">TRACE 1600</a> and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/486">1610 GC</a> show up inside OpenLab just like the instruments customers are used to, giving users a modern, robust GC platform without disrupting the software environment they depend on. The integration is fully supported across the most commonly installed OpenLab versions 2.6, 2.7, 2.8, and 2.84, and works seamlessly in Windows 11 systems.In other words, labs don’t need to change their CDS at all. They don’t need to modify workflows, rewrite methods, or retrain their teams. They can keep everything exactly as it is, from the user interface to the reporting structures, while simply upgrading to a new, reliable hardware. For many laboratories, this alone removes the biggest barrier to exploring something new.<h3>Designed for the realities of industrial GC analysis</h3>The TRACE 1600 Series GC were built with industrial environments in mind, and that shows up in ways users immediately appreciate. For starters, the system emphasizes reliability and uptime. Its Integrated Electronic Control (IEC) is engineered for long-term stability, and the overall hardware is designed to stay online through continuous, high-throughput use.Another key benefit of the TRACE 1600 Series GC is modularity. Anyone who has worked in an industrial lab knows that maintenance windows are tight, and every minute counts. The TRACE 1600’s modular design makes it easy to access injector and detector modules, swap parts quickly, and get the instrument back online with minimal disruption. It also means that service visits tend to be smoother and faster, something that matters enormously in an environment where production schedules don’t stop.Flexibility is another important aspect. Industrial workflows aren’t all the same, and the TRACE 1600 Series supports a wide range of self-installable inlet and detector modules, from SSL, SSL-HeSaver and PTV to FID, TCD, ECD, NPD, FPD, and PDD, offering unlimited configurations available when needed, for applications ranging from basic QC to more complex analyses. Additionally, the modules are fully exchangeable between Thermo TRACE GC systems, getting the most out of the existing GC system in the lab.Many labs also appreciate that the TRACE 1600 Series uses common consumables, meaning they don’t have to overhaul their purchasing processes or introduce new suppliers.When you put all this together, the reliability, the modularity, the application flexibility, and the drop-in OpenLab CDS compatibility, the result is a GC platform that genuinely makes life easier for industrial labs. It helps them overcome possible hardware challenges slowing them down, without forcing them into the costly and time-consuming process of changing the software environment they rely on.For industrial laboratories that have felt stuck between the opportunity of new solutions and the fear of disrupting their CDS workflows, the TRACE 1600 Series GC offers a way forward.It is time to explore a GC platform engineered for uptime and stability.<ul><li>Visit us on <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/gas-chromatography-gc/gc-systems.html">Gas Chromatography Systems for High Performance Workflows</a></li><li>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#ChemicalAnalysis #ChromatographyDataSystem #GasChromatography #Industrial</li></ul><section><blockquote><h5>Dr. Daniela Cavagnino</h5>Dr. Daniela Cavagnino is Product Marketing Manager for GC and Sampling Solutions. She started her career in gas chromatography at Thermo Fisher Scientific spending several years in the R&amp;D laboratories working on GC technology innovation. Then, she conveyed her technical background into product management and marketing management roles with more than 20 years’ experience in promoting GC/GCMS technology and applications in several different market segments.</blockquote></section>

A Better Path for Industrial GC Users — How the TRACE 1600 Series GC Delivers Reliability, Innovation, and Seamless OpenLab CDS Integration

<h3>Introduction</h3>Modern analytical laboratories often operate multiple chromatographic instruments simultaneously, which places high demands on software usability and workspace navigation. <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/999">Clarity Chromatography Software</a> developed by DataApex provides a structured, instrument-oriented user interface designed to simplify work even in complex multi-instrument environments. This article explains how to efficiently move between windows in Clarity.<h3>Concept of Instrument-Centric Workspace Organization</h3><h4>Instrument-Specific Color Schemes</h4>Each instrument in Clarity is visually distinguished by its own color scheme. This design choice allows users to:<ul><li>Instantly recognize which windows belong to the same instrument</li><li>Avoid confusion when multiple instruments are open simultaneously</li><li>Maintain orientation within complex analytical workflows</li></ul>Color coding is consistent across all windows associated with a given instrument.<h3>Types of Windows in Clarity</h3>Within a single instrument context, Clarity typically provides access to several interconnected windows, including:<ul><li>Instrument Window – the central control and overview window</li><li>Chromatogram Window – displays acquired chromatographic data</li><li>Sequence Window – manages sample sequences and runs</li></ul>Efficient navigation between these windows is essential for smooth operation.<h3>Navigation Methods Between Windows</h3>Clarity offers multiple complementary ways to switch between related windows. Users can choose the method that best fits their workflow preferences.<h4>1. Instrument Window Tiles</h4>Within the Instrument Window, large tiles represent related windows.Example workflow:<ul><li>Select the large chromatogram tile to switch directly from the Instrument Window to the Chromatogram Window</li></ul>This tile-based approach is intuitive and visually guided.<h4>2. Toolbar Icons</h4>Each instrument window contains a toolbar with window icons that provide direct access to other related windows.Key characteristics:<ul><li>The same set of window icons is available across all instrument-related windows</li><li>Enables quick transitions, for example:<ul><li>From Chromatogram Window → Sequence Window</li></ul></li><li>Ideal for experienced users who prefer icon-based navigation</li></ul><h4>3. Window Menu</h4>For users who prefer menu-driven control, Clarity includes a Window menu.Typical use case:<ul><li>Select Main from the Window menu to return to the Clarity main window</li></ul>This method is particularly useful when:<ul><li>Navigating back to the global workspace</li><li>Managing multiple instruments at once</li></ul><h3>Practical Navigation Workflow Example</h3>A typical navigation sequence demonstrated in the video follows this logic:<ol><li>Start in the Instrument Window</li><li>Click the Chromatogram tile to open chromatographic data</li><li>Use the toolbar icon to switch to the Sequence Window</li><li>Open the Window menu and select Main to return to the Clarity main interface</li></ol>This combination of tiles, icons, and menus ensures flexible and efficient workspace control.<h3>Advantages of Clarity’s Navigation Design</h3>The navigation system in Clarity provides several practical benefits:<ul><li>Consistency – identical navigation tools across instrument windows</li><li>Efficiency – rapid switching without losing context</li><li>Scalability – effective even with many instruments open</li><li>User preference flexibility – toolbar or menu-based workflows</li></ul>These features are especially valuable in high-throughput laboratories and 24/7 operational environments.<h3>Conclusion</h3>Clarity Chromatography Software uses a well-structured, instrument-oriented window system that simplifies navigation even in complex multi-instrument setups. By combining color-coded instruments, tile-based access, universal toolbar icons, and traditional menus, Clarity allows users to move quickly and confidently between windows.Mastering these navigation techniques significantly improves workflow efficiency, reduces errors, and enhances overall user experience—making Clarity a robust platform for modern chromatographic laboratories.For additional tutorials and practical demonstrations, users are encouraged to explore further educational resources provided by DataApex.

How to switch between the Clarity Windows

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Agilent O-ring, 2-320, fluorocarbon for 7000 GC/QQQ, 0905-1592 (New)

Agilent O-ring (2-320), fluorocarbon for 7000 GC/QQQ. Ensures leak-free sealing, durability, and stable system operation.

Agilent O-ring, 0.362ID,0.103W, BunaN,70,568A-110 (New)

Agilent O-ring, Buna-N 70A, 0.362″ ID × 0.103″ W, 4035-0012 / 568A-110. Durable seal for fluidic and vacuum connections in Agilent instruments.

Agilent Tee, 1/8 in, brass, 0100-0090 (New)

Brass tee fitting (1/8", 0100-0090) designed for secure gas distribution in GC and ICP systems. Provides reliable, leak-free sealing, durability, and long service life.

Agilent 1/8 Nut And Ferrule Set Brass Swagelok, 5181-7481 (New)

Agilent 1/8″ brass nut and ferrule set (5181-7481) for GC gas systems. Provides secure, leak-free sealing, long service life, and mechanical strength.

Agilent Internal nut, CFT capillary fitting, G2855-20530 (New)

The Agilent internal nut (G2855-20530) is designed for use with Capillary Flow Technology (CFT) capillary fittings.

Agilent Column storage fitting, G2855-20590 (New)

The Agilent column storage fitting (G2855-20590) is designed to protect capillary GC columns during storage or transport.

Agilent Needle, headspace transfer line, deactivated, 0.5 mm od, 0.2 mm id., 2322590004 (New)

Agilent deactivated headspace transfer line capillary (0.5 mm OD, 0.2 mm ID) ensures inert sample transfer in GC-HS. Compatible with G1289A/B, G1290B, G1883A.

Agilent Septum retainer nut, for transfer line, G3452-60835 (New)

Agilent Septum Retainer Nut (G3452-60835) for transfer lines ensures a secure septum seal, preventing leaks and maintaining reliable GC/MS performance.

Agilent Tee, 1/4 in, brass, 0100-0088 (New)

Agilent 1/4-inch brass tee (0100-0088) provides a durable, leak-tight 3-way connection for GC gas lines and laboratory fluid systems.

Agilent 1/4" Brass Nut & Ferrule, 5183-0392 (New)

Agilent 5183-0392 1/4" brass nut & ferrule set provides durable, leak-tight compression connections for GC gas lines and general lab gas distribution.

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KnowItAll 2026.1 maintenance release now available - Upgrade for the latest features and fixes