<p><strong>In the week from January 13, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>3 500 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Shimadzu Corporation: Enhancing Non-Targeted Screening In Challenging Matrices</strong></h5><div><div><ul><li><div>We, 15.1.2025 09:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4570">Registration</a></div></li></ul></div><p>Don’t miss this opportunity to experience the future of non-targeted screening and explore how GCxGC-TOF MS can elevate your research!</p></div><h5><strong>2.&nbsp;Agilent Technologies: Agilent 8700 LDIR Workflows</strong></h5><div><div><ul><li><div>Th, 16.1.2025 20:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4637">Registration</a></div></li></ul></div><p>The two main worklflows of the LDIR will be discussed and demonstrated.</p></div><h5><strong>3. Agilent Technologies: All About USP 467 Residual Solvent: Regulatory and Application Updates</strong></h5><div><div><ul><li><div>Tu, 21.1.2025 17:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4513">Registration</a></div></li></ul></div><p>Recent changes in USP 467, latest trends &amp; applications in residual solvent analysis along with analytical workflow in order to get accurate &amp; reproducible results.</p></div><h5><strong>4. Agilent Technologies:</strong> <strong>Make Your GC lab more productive with OpenLab CDS</strong></h5><div><div><ul><li><div>We 22.1.2025 10:30 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4671">Registration</a></div></li></ul></div><p>The latest variant of OpenLab CDS. OpenLab CDS in sync with GC platform provides latest features familiarization to ensure your lab is productive, efficient and compliant.</p><div>&nbsp;</div></div><h5><strong>5. Agilent Technologies:</strong> <strong>Using LDIR for Advanced Microplastics Characterization</strong></h5><div><div><ul><li><div>Th, 23.1.2025 09:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4683">Registration</a></div></li></ul></div><p>This session will highlight the advanced features of LDIR technology and its critical applications in analyzing microplastics within various matrices.</p></div><h5><strong>6.&nbsp;Waters Corporation: Empower Tips: Ask Me Anything About Navigating Data Governance - Risk and Vigilant Monitoring</strong></h5><div><div><ul><li><div>Th, 23.1.2025 16:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4550">Registration</a></div></li></ul></div><p>We will explore critical aspects of data governance and critical thinking, insights and strategies to help navigate the current environment, evolving your approach and modernizing your way of working.</p></div>

Webinars LabRulezGCMS Week 3-4/2025

A fast thermal desorption unit for micro thermal desorption tubes, Part I: Development of the system and proof of concept measurements with hyper-fast gas chromatography

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 13th January 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you applications and other documents by <strong>Agilent Technologies</strong>, <strong>Thermo Fisher Scientific</strong>,<strong> </strong>and<strong> Shimadzu</strong>!</p><h4><strong>1. Thermo Fisher Scientific: </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_7000_mrm_toxicology_asms_2024_wp810_en_agilent_b9f153ff37.pdf"><strong>HERAtech Laboratories satisfies growing water-analysis demand and reduces costs using workflow automation</strong></a></h4><ul><li>Case study</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/28639"><strong>Full PDF for download</strong></a></li></ul><p><i>“Automation is fundamental because thirteen analysts are not enough to cope with our increase in samples. The automated approach we use allows for method consolidation with the analysis of PAHs and pesticides in a single GC run. Additionally, the possibility to perform sample extraction automatically, followed by online GC-MS/MS analysis, offers a significant reduction of labor spent and a significant reduction in solvent consumption.”</i></p><p><i><strong>Dr. Paolo Morelli</strong>, Laboratory Manager, HERAtech S.r.l., Sasso Marconi (BO), Italy</i></p><p><i>“It’s necessary to evaluate every possible marginal gain on every single process in the workflow to remove any bottlenecks. The bottleneck that Thermo Fisher Scientific has helped us solve is huge for sample preparation for pesticides and in particular for PAHs by eliminating manual SPE.”</i></p><p><i><strong>Dr. Paolo Morelli</strong>, Laboratory Manager, HERAtech S.r.l., Sasso Marconi (BO), Italy</i></p><blockquote><h5><strong>Analytical system used at HERAtech for automated determination of pesticides and PAHs in water samples</strong></h5><ul><li>TriPlus RSH SMART autosampler</li><li>Thermo Scientific™ TRACE ™ 1610 Series gas chromatograph with Thermo Scientific™ iConnect™ Programmable Temperature Vaporizing (PTV) injector module for large-volume injection</li><li>Thermo Scientific™ TSQ™ 9610 triple quadrupole mass spectrometer</li></ul></blockquote><p><i>“The key aspect of this automated solution is an analytical system capable of carrying out automatically, in a fully unattended way, all the extraction phases of the LLE protocol using microvolumes.”</i></p><p><i><strong>Dr. Paolo Morelli</strong>, Laboratory Manager, HERAtech S.r.l., Sasso Marconi (BO), Italy</i></p><p><i>“We made significant investments focused on automation in terms of instruments that allow us to analyze more analytes in one run. In particular, we aimed to consolidate different methods into a single method and provide as many analytical measurements as possible with a single machine. Our goal was simultaneous analysis of 70 analytes including pesticides and PAHs, with quantification limits between 0.0005 μg/L (0.5 ng/L) and 0.02 μg/L.”</i></p><p><i><strong>Dr. Paolo Morelli</strong>, Laboratory Manager, HERAtech S.r.l., Sasso Marconi (BO), Italy</i></p><p><i>“Only two solvents are necessary to perform automated DLLME, and the much lower volumes offer significant cost savings. The sample volume required is much lower, reducing logistic costs of transportation and storage.”</i></p><p><i><strong>Dr. Paolo Morelli</strong>, Laboratory Manager, HERAtech S.r.l., Sasso Marconi (BO), Italy</i></p><h4><strong>2. Agilent Technologies/ASMS: A Triple Quadrupole GC/MS MRM Database for Forensic and Toxicological Workflows</strong></h4><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/27204"><strong>Full PDF for download</strong></a></li></ul><p>Systematic toxicological analysis in forensic investigation demands continuous adaptability to an ever-evolving toxicant landscape.</p><p>The three main challenges are:</p><ol><li>low concentrations of the toxicants</li><li>an ever-growing number of analytes to be monitored and quantitated</li><li>the limitations in obtaining analytical standards for every chemical.</li></ol><p>For the volatile compounds, gas chromatography/mass spectrometry (GC/MS) is the method of choice when analyzing forensic drugs and toxicants [1, 2]. GC/MS <strong>forensic toxicological workflow</strong> greatly benefits from <strong>selectivity</strong> and <strong>sensitivity</strong> of multiple reaction monitoring (MRM) approach enabled with triple quadrupole GC/MS (GC/TQ).</p><p>The aim of this work was to develop an <strong>MRM database</strong> to help toxicological researchers build screening and quantitation methods simplifying method development.</p><p>The database of MRM transitions for relevant toxicants was established and successfully applied to creating GC/TQ methods for analyzing real-world authentic samples with <strong>greater sensitivity and confidence</strong> than the conventional GC/MS approach. The database will be available for download starting July 2024.</p><h4><strong>3. Shimadzu: GC/GC-MS Glass Insert/Liner Selection Guide</strong></h4><ul><li>Guide</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/26962"><strong>Full PDF for download</strong></a></li></ul><p>In a gas chromatograph, the sample is injected into the column via the injection unit. A glass insert / liner is used to vaporize the sample more efficiently, and to inject the vaporized sample into the column with no unnecessary dispersion. Additionally, using a glass insert reduces the extent to which contaminants such as high boiling point compounds from the sample contaminate the injection unit. Accordingly, selecting a glass insert appropriate for the objective heightens the accuracy of analysis and leads to more reliable results.</p><p>When selecting a glass insert, various selection standards are used depending on the application. For example, the following cases can be cited as selection standards for glass inserts.&nbsp;</p><ul><li>What type of injection unit is used? What sample injection method is used during analysis?</li><li>Is the glass insert filled with wool (glass wool)? What shape is the glass insert?</li><li>What are the dimensions of the glass insert?</li><li>Is surface treatment of the glass insert necessary?</li></ul><p>Glass inserts with a variety of specifications are commercially available to suit these varied selection criteria, so selecting a glass insert can be daunting.</p><p>This selection guide describes how to select an appropriate glass insert for the objective/application as well as points to consider in accordance with elements of the glass insert configuration. Additionally, this guide introduces glass inserts appropriate for your Shimadzu GC system.</p>

News from LabRulezGCMS Library - Week 3, 2025

<p><strong>In the week from January 20, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Agilent Technologies: All About USP 467 Residual Solvent: Regulatory and Application Updates</strong></h5><div><div><ul><li><div>Tu, 21.1.2025 17:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4513">Registration</a></div></li></ul></div><p>Recent changes in USP 467, latest trends &amp; applications in residual solvent analysis along with analytical workflow in order to get accurate &amp; reproducible results.</p></div><h5><strong>2. Agilent Technologies:</strong> <strong>Make Your GC lab more productive with OpenLab CDS</strong></h5><div><div><ul><li><div>We, 22.1.2025 10:30 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4671">Registration</a></div></li></ul></div><p>The latest variant of OpenLab CDS. OpenLab CDS in sync with GC platform provides latest features familiarization to ensure your lab is productive, efficient and compliant.</p><h5><strong>3. LECO: Two-Dimensional Gas Chromatography Coupled with Electron and Chemical Ionization Mass Spectrometry for the Analysis of Aviation Fuels</strong></h5><div><div><ul><li><div>We, 22.1.2025 20:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4688">Registration</a></div></li></ul></div><p>The identification of different types of unknown compounds in complex mixtures by using GCxGC coupled with TOF mass spectrometry using positive-ion mode EI and methane CI is discussed.</p></div></div><h5><strong>4. Agilent Technologies:</strong> <strong>Using LDIR for Advanced Microplastics Characterization</strong></h5><div><div><ul><li><div>Th, 23.1.2025 09:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4683">Registration</a></div></li></ul></div><p>This session will highlight the advanced features of LDIR technology and its critical applications in analyzing microplastics within various matrices.</p></div><h5><strong>5.&nbsp;Waters Corporation: Empower Tips: Ask Me Anything About Navigating Data Governance - Risk and Vigilant Monitoring</strong></h5><div><div><ul><li><div>Th, 23.1.2025 16:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4550">Registration</a></div></li></ul></div><p>We will explore critical aspects of data governance and critical thinking, insights and strategies to help navigate the current environment, evolving your approach and modernizing your way of working.</p></div>

Webinars LabRulezGCMS Week 4/2025

A fast thermal desorption unit for micro thermal desorption tubes, Part II: Method development and validation for explosives and chemical warfare agent simulants

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 20th January 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you applications and other documents by <strong>Shimadzu, Agilent Technologies </strong>and <strong>Thermo Fisher Scientific</strong>!</p><h4><strong>1. Shimadzu Corporation: Analysis of Volatile Organic Compounds (VOCs) in Water Using Trap-Headspace-GCMS in Accordance with US EPA Method 8260D Criteria</strong></h4><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/28645"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li>Using trap-headspace-GCMS as an alternative technique to purge-and-trap with GCMS in accordance with US EPA Method 8260D criteria for the analysis of VOCs in water matrix.</li><li>Capability of analyzing volatile organic compounds (VOCs) at very low limit of quantitation, as low as 0.5 ng/mL.</li></ul><h5><strong>Introduction</strong></h5><p>According to United States Environmental Protection Agency (US EPA), volatiles organic compounds (VOCs) are defined as compounds with high vapor pressure that can easily evaporate into gases. Improper dumping of waste or industrial leachates contaminates underground water. This contaminated water exposes humans to VOCs in their daily lives. Each VOC poses different exposure risk based on its individual constituents. To protect human health and the environment, the US EPA developed Method 8260D1) to identify and quantify VOCs in water using single quadrupole GCMS.</p><p>Purge-and-trap is a common sampling technique for this application. However, in this study, Shimadzu’s Trap-Headspace system is utilized as an alternative sampling technique and is evaluated against EPA 8260D criteria. VOCs sampled from the headspace are concentrated in a trap before being injected into the GC, providing high sensitivity in the analysis. The headspace system, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=6&amp;mainauthorItems=1&amp;search=HS-20+NX"><strong>HS-20 NX</strong></a> (Trap Model), also features heated and inert sample lines with a short transfer line to suppress analytes adsorption. In this application news, the HS-20 NX (Trap Model) is coupled with <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=3&amp;mainauthorItems=1&amp;search=QP2020+NX"><strong>Shimadzu GCMS-QP2020 NX</strong></a> (Fig. 1) to achieve high sensitivity in VOCs in water analysis.</p><h5><strong>Conclusion</strong></h5><p>The analysis results unequivocally validate the concept of using trap-headspace system as a viable pretreatment method for further exploration and application for the US EPA Method 8260D.</p><h4><strong>2.&nbsp;Agilent Technologies: Analysis of Sulfides, Formaldehyde, and Organic Halides in High-Purity Hydrogen for Fuel Cell Vehicles</strong></h4><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/28649"><strong>Full PDF for download</strong></a></li><li>Using an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890"><strong>8890 GC</strong></a>/<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8355"><strong>8355 SCD</strong></a>/<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=5977"><strong>5977 MSD System</strong></a></li></ul><h5><strong>Abstract</strong></h5><p>This application note describes a robust analytical procedure for the detection of sulfides, formaldehyde, and organic halides in hydrogen for fuel cell vehicles. This analysis was executed using an Agilent 8890 gas chromatography (GC) system equipped with an Agilent 8355 sulfur chemiluminescence detector (SCD) and an Agilent 5977 mass spectrometer detector (MSD). Samples were preconcentrated using a thermal desorption system, followed by separation on an Agilent J&amp;W DB-Sulfur SCD column. A purged two-way splitter was used to split the sample at a 3:1 ratio onto the SCD and MSD. This flexible configuration demonstrated excellent performance for these three categories of compounds. The correlation coefficients for all target compounds exceeded 0.9971, with reproducibility results varying between 0.3% and 7.9%. The detection limits for sulfides, formaldehyde, and organic halides were 0.01, 0.1, and 0.5 nmol/mol, respectively.</p><h5><strong>Introduction</strong></h5><p>Contrasted with traditional internal combustion engine vehicles, hydrogen fuel cell vehicles (FCVs) that use hydrogen as an energy source present many advantages. These advantages include superior conversion efficiency and zero emissions, thus being esteemed as another groundbreaking revolution in the automobile industry.<sup>1</sup> FCVs deploy proton exchange membrane fuel cells (PEMFCs), transforming chemical energy into electrical energy through the reaction between hydrogen and oxygen facilitated by a catalyst. The purity of hydrogen fundamentally determines the battery performance and lifespan. Hydrogen derived from fossil fuels, for example, referred to as grey hydrogen, is a substantial source. Grey hydrogen can include impurities, such as sulfides, carbon monoxide, carbon dioxide, ammonia, light hydrocarbons, formaldehyde, formic acid, and inert gases originating from the raw materials or the chemical reaction process.<sup>2</sup> Other colors of hydrogen from different sources may include various combinations of impurities as well. These impurities are crucial elements affecting the durability of the fuel cell. Sulfides are severe catalyst poisons, causing irreversible degradation of fuel cell performance even at part per trillion (ppt) levels. Both CO and CO<sub>2</sub> impurities in the hydrogen fuel can cause fuel cell performance degradation, with CO being more severe. Formaldehyde, an intermediate product in the process of hydrogen production from natural gas or methanol, has a poisoning mechanism like CO, but is more harmful. Trace amounts of ammonia can decrease the mass transfer ability of the electrolyte membrane, leading to irreversible degradation of the battery performance. Halides also irreversibly affect the performance of hydrogen fuel cells. Inert impurities in hydrogen (such as He, Ar, N<sub>2</sub>) do not poison the fuel cell but dilute the hydrogen fuel, reducing the cell potential and leading to power loss.</p><p>To ensure the long-term stable operation of hydrogen fuel cells, various organizations have established quality standards for hydrogen used in FCVs. The International Organization for Standardization (ISO) and the Society of Automotive Engineers (SAE) in the United States have established specific standards for hydrogen used in PEMFCs, namely ISO 14687-20193 and SAE J2719-2015.4 China has also established GB/T 37244-20185 to regulate the quality of hydrogen products. These standards consistently specify limits for certain impurities in hydrogen, such as sulfides not exceeding 0.004 μmol/mol, formaldehyde not exceeding 0.01 μmol/mol, and total halides not exceeding 0.05 μmol/mol. The GB/T 44243-20246 method details the determination of sulfide, formaldehyde, and organic halides in hydrogen for FCVs, gives reference instrument configurations, and also presents performance results.</p><p>In accordance with those standards, this study has established a comprehensive analytical method for multiple key trace impurities in hydrogen for FCVs. An analytical platform has been designed for seven sulfides, formaldehyde, and eight organic halides. Sulfides are detected using a GC/SCD, while formaldehyde and organic halides are detected using a GC/MSD. The detection limits of all compounds in this study fully met the requirements for hydrogen quality control described in ISO 14687-2019, SAE J2719-2015, and GB/T 37244-2018 methods.</p><h4><strong>3.&nbsp;Thermo Fisher Scientific: Gas chromatography consumables ordering guide</strong></h4><ul><li>Guide</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/28640"><strong>Full PDF for download</strong></a></li></ul><p>Proven consumables for optimum system performance.</p><h5><strong>Select the right GC consumable for your GC system</strong></h5><p>Optimize your gas chromatography (GC) system’s performance by selecting the proper GC consumables. Reference the compatibility and recommended use when ordering your consumables for the following systems:</p><ul><li>Thermo Scientific™ TRACE™ 1300 and TRACE™ 1600 Series Gas Chromatographs</li><li>Thermo Scientific™ AI/AS 1310 and AI/AS 1610 Liquid Autosamplers</li><li>Thermo Scientific™ TriPlus™ RSH and TriPlus™ RSH SMART Autosamplers</li><li>Thermo Scientific™ TriPlus™ 500 Headspace Autosampler</li></ul><h5><strong>Contents</strong></h5><ul><li>GC syringes and SPME arrows and fibers<ul><li>AI/AS 1310 and AI/AS 1610 liquid autosamplers</li><li>TriPlus RSH and TriPlus RSH SMART autosamplers</li></ul></li><li>Injection ports<ul><li>iConnect Split/Splitless (SSL) injector module</li><li>iConnect Programmable Temperature Vaporizer (PTV) injector module</li></ul></li><li>Mass spectrometer transfer line connections</li><li>Gas management</li><li>GC columns</li><li>GC column connectors</li><li>Sample handling</li></ul>

News from LabRulezGCMS Library - Week 4, 2025

<p><strong>In the week from January 27, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Agilent Technologies: Sample ID and Material Analysis by Handheld FTIR</strong></h5><div><div><ul><li><div>Tu, 28.1.2025 11:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4645">Registration</a></div></li></ul></div><p>Learn how the Agilent 4300 can deliver an actionable result at site or in production in less than 30 seconds.</p></div><h5><strong>2.&nbsp;Separation Science/Markes International: Real-World Implementation of Dual Canister and Tube Analysis of Hazardous Air Pollutants Using TD–GC–MS</strong></h5><div><div><ul><li><div>Tu, 28.1.2025 11:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4642">Registration</a></div></li></ul></div><p>In this webinar, join environmental chemistry experts as they share Biochemie Lab’s journey in integrating both canister and tube sampling.</p></div><h5><strong>3.&nbsp;Mettler-Toledo: Routine Testing of Balances and Scales</strong></h5><div><div><ul><li><div>Tu, 28.1.2025 14:30 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4657">Registration</a></div></li></ul></div><p>This webinar will give you a good understanding of why balance and scale testing is crucial for the accuracy of your weighing results in laboratory and production environments.</p></div><h5><strong>4.&nbsp;Technology Networks/Agilent Technologies: From Residues to Regulations: The Evolution of Pesticide Analysis With GC-MS</strong></h5><div><div><ul><li><div>We, 29.1.2025 17:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4689">Registration</a></div></li></ul></div><p>This live panel discussion will explore key challenges faced by the industry, technological innovations driving change and emerging trends that are shaping the future of pesticide analysis.</p></div><h5><strong>5.&nbsp;US HUPO: Don’t Just Trust the Algorithm: Why You Need To Look at Your Spectra</strong></h5><div><div><ul><li><div>We, 29.1.2025 18:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4679">Registration</a></div></li></ul></div><p>Join us for a lesson in how to look at your spectra from Sue Weintraub. Using examples from her research, Sue will highlight the importance of looking at mass spectra and teach you how to get started.</p></div>

Webinars LabRulezGCMS Week 5/2025

<p><strong>In the week from February 3, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Agilent Technologies: Peak Perfection: A Guide to GC troubleshooting</strong></h5><div><div><ul><li><div>Tu, 4.2.2025 17:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4514">Registration</a></div></li></ul></div><p>We will discuss some of the most common chromatographic issues that you experience with Gas Chromatography and take a logical approach to finding the root cause and correcting the problem.</p></div><h5><strong>2. GERSTEL: Determination of mineral oil residues HPLC-GC analysis of MOSH &amp; MOAH</strong></h5><div><div><ul><li><div>We, 5.2.2025 10:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4639">Registration</a></div></li></ul></div><p>Experience the LC-GC-FID analysis for MOSH/MOAH in our informative webinar! We will introduce you to the key features of the GERSTEL LC-GC-FID system and show you how it simplifies your daily work.</p></div><h5><strong>3. DataApex: Clarity 10 Webinar</strong></h5><div><div><ul><li><div>Th, 6.2.2025 09:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4696">Registration</a></div></li></ul></div><p>Discover the new Dual Chromatogram Mode for dual tower samplers, enhanced User Account settings, updated control modules, Extensions' improvements, and more.</p></div><h5><strong>4. Anton Paar: Data Integrity - the Anton Paar way</strong></h5><div><div><ul><li><div>Th, 6.2.2025 10:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4551">Registration</a></div></li></ul></div><p>Data integrity has now been extended from the device to the AP Connect Pharma edition. This software allows you to store, verify, and validate your data easily in your own SQL database.</p></div><h5><strong>5. Technology Networks: Toward More Sustainable Labs: The Impact of Gas Supply</strong></h5><div><div><ul><li><div>Th, 6.2.2025 15:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4690">Registration</a></div></li></ul></div><p>This webinar will discuss the improvements you could make to your lab’s sustainability goals with the introduction of on-site gas generation.</p></div><h5><strong>6. Agilent Technologies: Eliminate errors with automation and stress-free sample tracking</strong></h5><div><div><ul><li><div>Th, 6.2.2025 17:00 CET</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4571">Registration</a></div></li></ul></div><p>Join us to hear about a new technology, linking samples and software for unprecedented control, to give you confidence in your laboratory workflow.</p></div>

Webinars LabRulezGCMS Week 6/2025

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 3rd February 2025? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you applications and other documents by <strong>Shimadzu, Agilent Technologies </strong>and <strong>Thermo Fisher Scientific</strong>!</p><h4><strong>1. Analysis of Essential Oils Using Comprehensive Two-Dimensional Gas Chromatography (GC × GC) and High-Resolution Mass Spectrometer</strong></h4><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_essential_oil_analysis_gcxgc_5994_8029en_agilent_7f4357b3cd.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The analysis of complex samples such as essential oils can benefit substantially from comprehensive two-dimensional gas chromatography (GC × GC), which provides a high degree of chromatographic separation due to the second dimension. Combining GC × GC with high-resolution accurate mass measurement increases the number of identifiable components and enhances confidence in the results.</p><p>The focus of this study was to establish a workflow for the analysis of essential oils using GC × GC with a reverse flow modulator (RFM) combined with a high-resolution quadrupole time-of-flight (GC/Q-TOF) mass spectrometer.</p><h5><strong>Experimental</strong></h5><p>The samples were separated on an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890"><strong>Agilent 8890 GC</strong></a> using a GC × GC configuration with an RFM and analyzed using a high-resolution accurate mass <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7250"><strong>Agilent 7250 GC/Q-TOF MS</strong></a> as well as an FID. A "normal" column set, combining a nonpolar primary column and a polar secondary column, was used. This set consisted of a 20 m × 0.1 mm, 0.1 μm Agilent DB-1ms column (100% dimethylpolysiloxane) and a 5 m × 0.25 mm, 0.15 μm Agilent DB-17ms column (equivalent to (50%-phenyl)-methylpolysiloxane).</p><p>To decrease flow to the MS, and to add an FID to the configuration as a second detector, the column flow must be split at the end of the secondary column by connecting it to a splitter. Two splitter types, purged and unpurged, have been explored to highlight the benefits and limitations of each configuration. In the case of a purged splitter, the column flow mixes with the makeup flow before splitting between the two detectors. In contrast, an unpurged splitter does not use makeup flow when splitting the column effluent between the two restrictors connected to the two detectors. A second FID (monitor, or vent) channel was added for method optimization and troubleshooting.</p><h5><strong>Conclusion</strong></h5><p>In this application note, a method for the analysis of essential oils using several comprehensive GC × GC configurations with a reverse flow modulator (RFM) and a high-resolution Agilent 7250 GC/Q-TOF system was developed. Method optimization was performed using a diesel sample. Essential oil components, separated by GC × GC, were reliably identified using the Unknowns Analysis tool. Agilent Mass Profiler Professional (MPP) software successfully determined the differences in chemical composition between the essential oils.</p><h4><strong>2.&nbsp;Utilizing hydrogen carrier gas for sensitive analysis of pesticides in food using gas chromatography mass spectrometry</strong></h4><ul><li>Poster / ASMS</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_142_utilizing_hydrogen_pesticides_food_gc_ms_po142_asms2024_en_7ed0951b93.pdf"><strong>Full PDF for download</strong></a></li></ul><p><strong>Purpose:</strong> To demonstrate the performance of the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=3&amp;search=HeSaver"><strong>Thermo Scientifc HeSaver-H2Safer kit </strong></a>for iConnect split-splitless (SSL) injection module for trace analysis of pesticides using H2 as a carrier gas as a safe and sustainable solution for laboratory operations.</p><p><strong>Methods: </strong>In this study, hydrogen was used as a carrier gas for <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=15&amp;mainauthorItems=3"><strong>GC-MS/MS analysis</strong></a> of trace levels of pesticides in food. The GC was fitted with a new hydrogen safer split/splitless injector, with chromatographic separation performed on a TG-5 SIL MS(30 m × 0.25 mm, 0.25 μm) capillary GC column. The chromatographic conditions applied ensured critical pair separation was achieved. The GC-MS/MS system was equipped with an advanced electron ionization (AEI) source to increase sensitivity for analyte detection. Quantification and assessment of critical regulatory requirements, such as linearity and sensitivity, were performed in a single software.</p><h5><strong>Conclusions</strong></h5><ul><li>The use of the HeSaver-H2Safer technology allows for a safe and compliant use of hydrogen as an alternative carrier gas in GC/GC-MS applications without the need to install a hydrogen sensor and removes any risk of unwanted reactions with the sample in the hot SSL injector.</li><li>When used with hydrogen, the limited carrier gas consumption offered by the HeSaver-H2Safer mode permits a very controlled system demand for hydrogen, making this solution ideal for laboratories working with hydrogen generators.</li><li>Migrating the GC-MS/MS method from helium to hydrogen requires an adaptation of method parameters to address (i.e., retention time shift and different fragmentation patterns).</li><li>97% of pesticides in baby food and 98% in honey showed a linear response in the concentration range 0.005–0.500 mg/kg and the relative standard deviation for N=5 repeats of each sample type at 0.01 mg/kg was equal or lower than 10% for 98% of the evaluated compounds.</li></ul><h4><strong>3.&nbsp;Analysis of VOC and SVOC Emissions from Automotive Interior Materials Using GCMS-QP2050 in Accordance with ISO 12219-11</strong></h4><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00845_en_9771953555.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=QP2050"><strong>GCMS-QP2050</strong></a> features a new interface that enables good peak shape and sensitivity even when analyzing compounds with high boiling points.</li><li>When used with the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=TD-30R"><strong>TD-30R</strong></a> thermal desorption system, it can analyze compounds in accordance with ISO 12219-11.</li><li>The TVOC Calculation Tool can calculate in a simple manner quantitative emissions (toluene and hexadecane equivalents) in accordance with ISO 12219-11.</li></ul><h5><strong>Introduction</strong></h5><p>In recent years, measures to reduce the use of organic compounds in automotive interiors have progressed, the ISO 12219-11 standard is being developed for the analysis of volatile organic compounds (VOCs) and semi-volatile organic compounds (SVOCs) that are emitted from automotive interior materials. The ISO 12219-11 analytical procedure involves filling a thermal desorption (TD) glass tube with a sample of materials, heating the tube using TD, and loading the VOCs (up to C25) and SVOCs (C14 to C32) that were emitted from the sample into a GC-MS system for analysis. Although this standardized procedure enables simple and quick analysis of VOC and SVOC emissions from these materials, contamination of the MS system caused by the simultaneous loading of compounds with high boiling points is a problem.</p><p>As shown in Fig. 1, the GCMS-QP2050 is equipped with a new contamination-resistant ion optical system that effectively minimizes contamination of the MS. Featuring a new interface (Fig. 2) that enables good peak shape and sensitivity even for compounds that are typically prone to adsorption, it is optimally suited to analyzing SVOCs, including those with high boiling points.</p><p>TD-30R and GCMS-QP2020 NX will be listed as examples for suitable test equipment on ISO 12219-11. This Application News describes analyzing VOC and SVOC emissions from the materials of vehicle interiors in compliance with ISO 12219-11 using the GCMS-QP2050 together with the NexisTM GC-2030 and the TD-30R thermal desorption system.</p><h5><strong>Conclusion</strong></h5><p>Using the new GCMS-QP2050, it was possible to consistently analyze SVOCs and other compounds with high boiling points. By combining this system with the TD-30R thermal desorption system and the TVOC Calculation Tool, even inexperienced users can rapidly analyze automotive interior materials and quantify emissions (i.e., calculate toluene and hexadecane equivalents) in compliance with ISO 12219-11.</p>

News from LabRulezGCMS Library - Week 6, 2025

<p><strong>In the week from February 10, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.</strong></p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></p><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>4 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Merck: Webinar Series &amp; Expert Roundtable (Day 1)</strong></h5><ul><li>Monday, February 10, 2025, 10:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4647">Registration</a></li></ul><p>Webinar Series &amp; Expert Roundtable (Day 1) - Navigating Quality Grades Part 1: Inorganics and Solvents for Classical Analysis and Research and Part 2: Solvents and Reagents for Chromatography Applications</p><h5><strong>2. Merck: Webinar Series &amp; Expert Roundtable (Day 2)</strong></h5><ul><li>Tuesday, February 11, 2025, 10:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4646">Registration</a></li></ul><p>Webinar Series &amp; Expert Roundtable (Day 2) - Part 1: Dihydropinene, γ-Valerolactone, and Dimethyl Isosorbide: Solvents for Organic Synthesis and Part 2: Enhance Your PFAS Testing</p><h5><strong>3. Mettler-Toledo: Laboratory Balance Cleaning</strong></h5><ul><li>Tuesday, February 11, 2025, 10:30 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4654">Registration</a></li></ul><p>Join our free live webinar to find out more about the benefits of and solutions for cleaning your balance.</p><h5><strong>4. Merck: Webinar Series &amp; Expert Roundtable (Day 3)</strong></h5><ul><li>Wednesday, February 12, 2025, 10:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4648">Registration</a></li></ul><p>Webinar Series &amp; Expert Roundtable (Day 3) - Part 1: Optimize Your Karl Fischer Titration and Part 2: Beyond Safety Standards – Best Practices for Safe Handling of Hazardous Chemicals</p><h5><strong>5. GERSTEL: Efficiency boost through automation MOSH/MOAH</strong></h5><ul><li>Wednesday, February 12, 2025, 10:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4640">Registration</a></li></ul><p>In this webinar we will show you the different sample preparation methods for MOSH &amp; MOAH analyses and their automation with the GERSTEL MultiPurpose Sampler.</p><h5><strong>6. C&amp;EN/Metrohm: From Challenges to Solutions: Revolutionizing Moisture Analysis with NIR and Titration</strong></h5><ul><li>Wednesday, February 12, 2025, 19:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4731">Registration</a></li></ul><p>Join industry experts as they explore modern approaches to moisture analysis in chemical, polymer, and petrochemical environments.</p><h5><strong>7. Merck: Webinar Series &amp; Expert Roundtable (Day 4)</strong></h5><ul><li>Thursday, February 13, 2025, 10:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4649">Registration</a></li></ul><p>Webinar Series &amp; Expert Roundtable (Day 4) - Part 1: Greener Solvents - Making Big Moves for More Sustainability in the Lab! and Part 2: Tips and Tricks for LC-MS Troubleshooting.</p><h5><strong>8. Thermo Fisher Scientific: Detecting PFAS in drinking water for regulations in Europe</strong></h5><ul><li>Thursday, February 13, 2025, 11:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4740">Registration</a></li></ul><p>Discover a comprehensive solution for PFAS analysis, from sample preparation to reporting, tailored to meet European regulatory standards.</p><h5><strong>9. Agilent Technologies: New Improvements to MP Workflow</strong></h5><ul><li>Thursday, February 13, 2025, 20:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4552">Registration</a></li></ul><p>Improvements to Microplastics workflow will be demonstrated.</p><h5><strong>10. Merck: Webinar Series &amp; Expert Roundtable (Day 5)</strong></h5><ul><li>Friday, February 14, 2025, 10:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4650">Registration</a></li></ul><p>Webinar Series &amp; Expert Roundtable (Day 5) - Roundtable Expert Discussion.</p>

Webinars LabRulezGCMS Week 7/2025

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