<p><strong>Join us for a free two-day LECO Separation Science Workshop on September 23–24, 2026, at the </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/219"><strong>C³AL Laboratory</strong></a><strong> at Cal State LA. Registration is free, and meals and refreshments will be provided throughout the workshop.&nbsp;</strong></p><h4><strong>Registration</strong></h4><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=iYeNbqIuykW7qZP4_jUEVbznDB40eK1PgjPzhHyb__9URTFTTFA5UEEzQ1A4MUtFV0o4TEJTNlZCOS4u&amp;route=shorturl"><strong>Register HERE</strong></a></p><p class="cke-user_style-important"><strong>Space is limited, register today!</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg" alt="LECO: LECO Separation Science Workshop - QR code for registration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg 156w," sizes="100vw" width="437" height="437"></p></blockquote><h4><strong>Hand-on Experience with the LECO Complex Chemical Composition Analysis Lab C<sup>3</sup>AL</strong></h4><ul><li>Work directly with LECO instruments in the C<sup>3</sup>AL Laboratory</li><li>Learn complete analytical workflows from sample to answer</li><li>Get expert guidance from LECO application scientists</li><li>Develop methods and solve real-world challenges</li><li>Collaborate, ask questions, and build your skills</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg" alt="Cal State LA: The LECO Pegasus BTX system in Cal State LA’s LECO Complex Chemical Compositional Analysis Lab enhances research and student training in advanced chemical analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg 227w," sizes="100vw" width="1252" height="863"></p><p>The first day will focus on the <strong>fundamentals and theory</strong> of comprehensive two-dimensional gas chromatography (<strong>GC×GC</strong>), with an emphasis on understanding how GC×GC can enhance your research, solve complex analytical challenges, and support your laboratory or company goals.&nbsp;</p><p>The second day will be dedicated to <strong>hands-on activities</strong>, giving participants the opportunity to work directly with <strong>LECO instrumentation</strong>, learn <strong>practical analytical workflows</strong>, and <strong>analyze their own samples</strong> with guidance from LECO application scientists.&nbsp;</p><p>Whether you are new to GC×GC or looking to expand its use in your research or organization, this workshop offers a unique opportunity to learn, explore, and apply the technology in a practical setting. Space is limited, so register early!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg" alt="Cal State LA: LECO QUADJET GCxGC coupled to Pegasus BT 4D TOM MS in the Complex Chemical Composition Analysis Lab (C³AL)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/thumbnail_Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg 234w," sizes="100vw" width="1949" height="1299"></p>

LECO Separation Science Workshop

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p><strong>The </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a><strong> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</strong></p><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/644"><strong>35th International Symposium on Chromatography</strong></a></h4><p>📆<strong>6. - 10. September 2026</strong></p><p>📍<strong>Prague, Czech Republic</strong></p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register HERE for the ISC 2026</strong></a></p><p><strong>Late Registration until 25 August 2026!</strong></p><p><strong>From 26 August 2026 only Onsite Registration.</strong></p></blockquote><h4><strong>Publishing Workshop</strong></h4><ul><li>Wednesday, 9 September 2026&nbsp;</li><li>12:30–14:00&nbsp;</li></ul><p>This interactive workshop will provide practical guidance on scientific publishing in the field of separation science. Participants will have the opportunity to hear directly from journal editors about key aspects of the publication process and how to improve their chances of successful publication.</p><p>Topics will include <strong>manuscript preparation, peer review</strong>, <strong>editorial decision-making, open access publishing</strong>, and the responsible <strong>use of artificial intelligence in scientific publishing</strong>. Editors will share insights into what they look for in submissions, common reasons for rejection, and strategies for preparing strong manuscripts. The workshop will also cover selected Wiley-specific topics, including the publisher’s submission platform and current guidelines on the use of AI in scientific publications.</p><p>The session will include opportunities for questions and discussion, allowing participants to interact directly with editors and gain valuable advice for their future publishing activities.</p><h5><strong>Attending Editors-in-Chief:</strong></h5><ul><li><strong>Michael Lämmerhofer</strong> — Journal of Separation Science and Separation Science Plus&nbsp;</li><li><strong>Sebastiaan Eeltink</strong> — Analytical Science Advances&nbsp;</li><li><strong>Mario Thevis</strong> — Drug Testing &amp; Analysis&nbsp;</li></ul>

Publishing Workshop at ISC 2026

<p><strong>We are excited to announce that the 18th MDCW will take place from January 25-27, 2027, in Liège, Belgium. This in-person event will feature:</strong></p><ul><li><strong>Keynote presentations</strong> from leading researchers</li><li><strong>Flash talks and poster sessions</strong> highlighting the latest innovations</li><li><strong>Focus group discussions</strong> addressing current challenges and future developments</li><li>💸<strong>FREE registration </strong>ensures that this event remains accessible to all researchers, students, and industry professionals interested in multidimensional chromatography. ​​We hope to see you there!</li></ul><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://app.oxfordabstracts.com/auth?redirect=https%3A%2F%2Fapp.oxfordabstracts.com%2Fregister%2Fevent%2F77272%3Fpreview%3Dfalse"><strong>Register HERE</strong></a></p><p><strong>Registration deadline: December 1, 2026</strong></p></blockquote><h3><strong>Abstract Submission</strong></h3><p>Abstracts for <strong>oral presentations</strong> must be submitted by <strong>September 15, 2026</strong>, to be considered.</p><p><strong>​Poster abstracts</strong> submitted by <strong>September 15, 2026</strong>, will be included in the <strong>preliminary program</strong>. Additional <strong>last-minute poster submissions </strong>will be accepted until <strong>November 30, 2026</strong>, for inclusion in the final program.</p><blockquote><p class="cke-user_style-important">👉<a target="_blank" rel="noopener noreferrer" href="https://app.oxfordabstracts.com/auth?redirect=/stages/81780/submitter"><strong>Submit your abstract HERE</strong></a></p><p><strong>&nbsp;Deadline for abstract submission: September 15, 2026</strong></p></blockquote><h4><strong>Presentation guidelines</strong></h4><h5><strong>Poster Presentations</strong></h5><ul><li><strong>Presenters must print and bring their own posters</strong>—onsite printing services and mailed submissions are not available.</li><li>Posters should be in <strong>landscape format: 36" tall × 48" wide</strong>.</li><li>Set up your poster <strong>during registration</strong> on the day of your assigned session and remove it at the <strong>end of the same day</strong>.</li><li>Poster presenters <strong>must</strong> be present at their posters during the designated poster session.</li><li>Posters will also be available for viewing <strong>during coffee and lunch breaks</strong>.</li><li>Presenters may optionally stand by their posters during these times for further discussions.</li></ul><h5><strong>Oral Presentations</strong></h5><ul><li><strong>Keynote presentations: </strong>30 minutes (25–28 min + Q&amp;A)</li><li><strong>Full oral presentations: </strong>20 minutes (18 min + 2 min Q&amp;A)</li><li><strong>Flash presentations: </strong>10 minutes (8 min + 2 min Q&amp;A)</li></ul><p><strong>Presentation Format:</strong></p><ul><li>Submit your slides as a <strong>PowerPoint (PPT)</strong> file (.ppt or .pptx).</li><li>Name your file with program code and surname, e.g. "O-28 Smith.pptx".</li><li>For optimal display, use <strong>16:9 slide format </strong>(4:3 is also supported).</li></ul><p><strong>Technical &amp; Session Logistics:</strong></p><ul><li>A <strong>headset or portable microphone</strong> will be available.</li><li>A <strong>laser pointer with a slide change button</strong> will be provided.</li><li>Ensure your presentation allows time for <strong>questions</strong> within your allocated time.</li><li><strong>Before your session</strong>, check in and introduce yourself to the conference or session chairs.</li></ul><h3><strong>Program</strong></h3><h4><strong>Keynote Speakers</strong></h4><h5><strong>Finding Clarity in Challenging Samples: Multiple Heart-Cutting 2D-LC and the Technologies That Enable It &nbsp; &nbsp;</strong></h5><ul><li>Stephan Buckenmaier (Principal Scientist R&amp;D, Agilent Technologies)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_Stephan_Buckenmaier_c84239ec30.jpg" alt="MDCW: Stephan Buckenmaier" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MDCW_Stephan_Buckenmaier_c84239ec30.jpg 151w," sizes="100vw" width="284" height="294"></p><p>Stephan Buckenmaier is a Principal Scientist in R&amp;D at Agilent Technologies, specializing in advanced separation science and the development of two-dimensional liquid chromatography (2D-LC) solutions. Since joining Agilent in 2006, he has held a variety of scientific and technical roles, with a particular focus on innovative chromatographic technologies. He earned his Ph.D. from the University of the West of England (Bristol, UK) and conducted postdoctoral research at the University of Tübingen. Stephan has authored numerous scientific publications, contributed a book chapter, and is listed as an inventor on numerous patents in the field of separation science. He regularly presents his work at international scientific conferences.</p><h4><strong>Short Course</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/18th_MDCW_short_course_41ecd3c6cf.jpg" alt="18th MDCW: Short course" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_18th_MDCW_short_course_41ecd3c6cf.jpg 245w," sizes="100vw" width="1100" height="619"></p><p>There will be <strong>20 spaces available</strong> in a short course related to multidimensional chromatography. If you want to register for the short course, indicate so during your registration. We will send a separate link to pay for the short course to reserve your seat (<strong>$50 USD</strong>).&nbsp;</p><h4><strong>A Beginner’s Guide to Multidimensional Chromatography short course</strong></h4><ul><li><strong>Instructors:</strong> Pierre-Hugues Stefanuto, Katelynn Perrault Uptmor, Dwight Stoll, Petr Vozka</li></ul><h5><strong>Course Description&nbsp;</strong></h5><p>So...you want to do multidimensional chromatography? If you are getting started in the field using either liquid or gas chromatography, you’re in the right place. This course will cover a brief history and introduction to both multidimensional gas chromatography and multidimensional liquid chromatography. Discussion will also include basic system components and data handling strategies to apply after acquiring your data. A hands-on portion of the course will also include familiarization with common system components and consumables for both GC and LC, as well as the opportunity to use a commercial GC×GC instrument.</p><h5><strong>Target Participants&nbsp;</strong></h5><p>This course is intended to be an initial touchpoint for those who are looking to explore multidimensional chromatography as a new option/capability, or who might be using it for the first time. The course is intended for new users to obtain a background on the techniques as a primer to the workshop. &nbsp;Advanced topics will not be discussed.</p><h5><strong>Course Logistics&nbsp;</strong></h5><ul><li>Morning Session (8:30 AM – 12:00 PM)</li><li>Afternoon Session (1:00 PM – 4:30 PM)</li></ul><p><strong>Lunch and coffee will be provided.</strong></p><h5><strong>Cost&nbsp;</strong></h5><p>A <strong>$50 fee</strong> is required to reserve a spot in the course. <strong>20 seats are available</strong>. An expression of interest form will be available to indicate interest in a seat within the course. On November 10th, participants will be informed about seat availability and the payment process will be communicated.</p><h4><strong>Outline (Total Time ~ 4 hrs)&nbsp;</strong></h4><h5><strong>Part I (1 hr) – History, Terminology, Fundamental Concepts&nbsp;</strong></h5><ul><li>Brief history of the development of multidimensional separations&nbsp;</li><li>Terminology&nbsp;</li><li>Fundamental Concepts&nbsp;<ul><li>In what ways are multidimensional separations useful for analytical chemistry / measurement science?&nbsp;</li><li>First and second separations should be orthogonal / complementary&nbsp;</li><li>Fast second dimension separations are important to avoid undersampling&nbsp;</li><li>Structured chromatograms can provide chemical insight and facilitate data interpretation&nbsp;</li><li>Highlights of an example data processing workflow – from raw data to actionable information &nbsp;</li></ul></li><li>Break (30 min)&nbsp;</li></ul><h5><strong>Part II (1.5 hrs) Introduction to Multidimensional Gas Chromatography&nbsp;</strong></h5><ul><li>Method basics&nbsp;<ul><li>Column selection&nbsp;</li><li>Method parameters&nbsp;</li><li>Carrier gas choices&nbsp;</li><li>Detector considerations&nbsp;</li></ul></li><li>Modulator selection with a focus on current market options&nbsp;<ul><li>Thermal modulators&nbsp;</li><li>Flow modulators&nbsp;</li><li>Other commercial options&nbsp;</li></ul></li><li>Method development made simple&nbsp;</li><li>Data preprocessing and initial handling&nbsp;</li><li>Lunch (1 hr)&nbsp;</li></ul><h5><strong>Part III (1 hr) Introduction to Multidimensional Liquid Chromatography&nbsp;</strong></h5><ul><li>Modes of multidimensional separation commonly used with LC&nbsp;<ul><li>Heartcut&nbsp;</li><li>Multiple heartcut / selective comprehensive&nbsp;</li><li>Fully comprehensive&nbsp;</li></ul></li><li>Interfaces used for multidimensional LC (i.e., the hardware that does the transfer from first to second dimension)&nbsp;</li><li>Common use cases of multidimensional LC illustrated using examples from industry and academic research&nbsp;<ul><li>Evaluating peak purity&nbsp;</li><li>Unknown identification via multidimensional and MS or NMR detection&nbsp;</li><li>Multi-stage separation with analyte transformation between stages&nbsp;</li><li>Multi-attribute methods&nbsp;</li><li>Making complete analysis of moderately complex samples attainable in a reasonable analysis time&nbsp;</li><li>Digging deeper – comprehensive separations for comprehensive analysis&nbsp;<br>Introduction to method development strategies&nbsp;</li></ul></li></ul><h5><strong>Part IV (2 hrs) Laboratory Instrument Familiarization</strong></h5><h5><strong>Part V (30 min) Wrap-up and Q&amp;A &nbsp;</strong></h5><h4><strong>Venue</strong></h4><ul><li>University of Liege</li><li>Pl. du Vingt Août 7</li><li>4000 Liège</li><li>​Belgium</li><li><strong>​Main Room:</strong> Salle Academique</li></ul>

18th MDCW - Registration and abstract submission opens

Article

Events

The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography Workshop

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

LECO

Separation Science

Thermo Fisher Scientific

Shimadzu Corporation

Plasmion

Spectroscopy & Separation Science

<h3><strong>Direct screening enables fast identification and comparison of substances</strong></h3>
<p>Fast &amp; Direct Screening enables to identify or compare different substances without any sample preparation.</p>
<h3><strong>Screening with quantification delivers reliable concentration levels</strong></h3>
<p>Screening with quantification not only enables a fast identification of substances but also provides reliable information about concentration levels to compare with standards or thresholds.</p>
<h3><strong>Automated all-in-one workflow simplifies routine analytics</strong></h3>
<p>All-in-one-Workflow reduces effort and cost in routine analytics as it enables to only perform detailed GC-MS analysis for positively screened samples.</p>
<h4><strong>Conventional Ionization Technologies</strong></h4>
<p>With conventional atmospheric pressure methods, the ions are mostly <strong>formed outside the inlet of an MS</strong>. This implies that the substance to be analyzed (e.g. coffee) cannot be analyzed directly, but is usually &quot;sprayed&quot; into the MS in the form of a sample (liquid extract) via the ionization source.</p>
<h4><strong>SICRIT® Technology</strong></h4>
<p>The SICRIT® (Soft Ionization by Chemical Reaction In Transfer) ionization source is <strong>interfaced with</strong> the atmospheric pressure <strong>inlet of the MS</strong> and ionizes every substance which is drawn into the MS by its inherent vacuum.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Plasmion_Conventional_MS_Ionization_Technologies_vs_SICRIT_Technology_8999716e25/Plasmion-Conventional-MS-Ionization-Technologies-vs.-SICRIT(r)-Technology.png" alt="Plasmion: Conventional MS Ionization Technologies vs. SICRIT® Technology"/></p>
<h4><strong>SICRIT® Characteristics</strong></h4>
<ul>
<li>Simple extension of MS inlet</li>
<li>Concentric dielectric barrier discharge</li>
<li>Sample ionized during transfer into MS</li>
<li>Soft ionization by proton transfer and UV light</li>
<li>No consumables</li>
</ul>


Plasmion: Direct MS Screening - Get Results Faster with SICRIT

Direct MS Screening - Get Results Faster with SICRIT

<p><strong>Solid-phase microextraction (SPME) has gained, since its introduction in the early 90s, a routine status in today’s analytical labs. Its simplicity of operation, ease of adoption and automation on a GC instrument makes it a valuable tool for many application fields. Variations from the classical SPME fiber configuration emerged in recent times.</strong></p>
<p>In this presentation we will show you and compare a recently developed SPME configuration (Arrow) with the classical SPME fibers with regards to dimensions, extraction and desorption behavior and analytical performance. Devices with PDMS coating as well as particle phases will be discussed. A special focus is put on the performance of the different particle adsorbent materials applied for the devices, as these are often used for sensitive headspace applications, a domain of SPME. Here differences in the particle structure and properties, in particular for the carbon particles, show a significant influence on the extraction and desorption behavior, and impact the analytical performance.</p>
<p>By attending this upcoming webinar you will learn</p>
<ul>
<li>the key differences between the classical SPME fibers and the recently developed configuration</li>
<li>the difference in analytical behavior</li>
<li>the importance of particle structure and properties for the extraction and desorption process.</li>
</ul>
<blockquote>
<p><strong>Presenter: Bob Shirey (Principal R&amp;D Scientist, MilliporeSigma, Bellefonte, Pennsylvania, USA)</strong></p>
</blockquote>
<blockquote>
<p>Bob Shirey received his BS degree in Chemistry from Shippensburg University and his MS degree in Biochemistry from West Virginia University. Bob started working at Supelco in 1984 as an R&amp;D chemist primarily focusing in sample preparation. Since 1993 Bob’s primary responsibilities have been on the development of SPME fiber coatings and hardware along with SPME applications. Bob has written multiple SPME articles for journals and contributed chapters for 2 books covering SPME. Bob continues to focus his efforts on SPME development and applications, and he especially enjoys helping customers with their SPME applications.</p>
</blockquote>


Pixabay/deepakrit: SPME Devices and Adsorbents – A Comparison

SPME Devices and Adsorbents – A Comparison

<p><strong>This is the fifth session in a series of webinars on fundamental concepts in gas chromatography.</strong></p>
<h3><strong>This session will cover:</strong></h3>
<ul>
<li>Headspace</li>
<li>Thermal desorption</li>
<li>SPME</li>
<li>Pyrolysis</li>
<li>Gas Sampling</li>
</ul>
<p>This series is perfect for anyone currently using GC, who&#39;d like to understand more about the technique, the hardware and the data produced. It&#39;s also suitable for anyone who is new to GC and who&#39;d like to understand more about it.</p>
<p>If you missed the previous sessions, we strongly recommend you watch them first. They are available to watch on <a href="www.shimadzu.co.uk/webinars">our website</a></p>
<h3><strong>Future sessions, which will be available from our website, will aim to cover:</strong></h3>
<ul>
<li>Choices of Detectors for GC</li>
<li>Processing GC Data </li>
<li>Maintenance &amp; Troubleshooting</li>
</ul>


Shimadzu: Shimadzu Theory & Key Principles Series - GC Session 5: Alternative to Liquid Injection

Shimadzu Theory & Key Principles Series - GC Session 5: Alternative to Liquid Injection

This is the fifth session will cover: Headspace, Thermal desorption, SPME, Pyrolysis, Gas Sampling.

GC Theory & Principles: Alternative to Liquid Injection

<p><strong>Separation Science, in collaboration with GERSTEL, Inc, offers an on-demand webinar describing applications using thin film solid-phase microextraction with analysis by thermal desorption GC/MS.</strong></p>
<blockquote>
<p><strong>Presenter: Jack Stuff, Ph.D. (Manager of the Analytical Services Group - GERSTEL, Inc.)</strong></p>
</blockquote>
<blockquote>
<p>Jack develops automated methods for sample preparation and introduction for gas chromatography-mass spectrometry. He develops and teaches customer training classes, conducts new product testing, and supports pre- and post-sales opportunities. He provides expert analytical support to a wide customer base including, food, flavor, fragrance, forensic, environmental, and chemical industries.</p>
</blockquote>
<h3><strong>Register for this on-demand learning event...</strong></h3>
<p>This webinar focuses on the use of TF-SPME for the analysis of a variety of sample types. Thin Film Solid- Phase Microextraction (TF-SPME) is an extension of regular SPME. It is simple to use and requires no solvent, yet it is more sensitive than regular SPME due to the increased surface area and phase volume.</p>
<p>The TF-SPME device is a 20 mm x 4.8 mm carbon mesh sheet that is impregnated with a sorptive phase. The TF-SPME devices can be used in headspace or immersive modes. In headspace mode, the TF-SPME device is suspended above a solid or liquid sample in an enclosed vial. In immersive mode, it is placed directly in a liquid sample. In both cases, the sample is agitated by stirring. After extraction, the devices are blotted dry and placed in an empty thermal desorption tube. They are analyzed by thermal desorption GC/MS. </p>
<h5><strong>By viewing this presentation you will learn:</strong></h5>
<ul>
<li>a new extraction technique and how it can be applied to different sample types.</li>
</ul>


GERSTEL: Applications using Thin Film Solid-Phase Microextraction (TF-SPME) with Analysis by Thermal Desorption GC/MS

Applications using Thin Film Solid-Phase Microextraction (TF-SPME) with Analysis by Thermal Desorption GC/MS 

<p><strong>There is a large number of flavoring substances, which occur in nature and are known to contain undesirable active components. These compounds are called biologically active flavorings. They are used to improve or modify the organoleptic properties of foods. They either alter or enhance the flavors of natural food, or they add flavor to food products that do not have the desired flavors.</strong></p>
<p>Some of these compounds, when consumed in large amounts can be very dangerous for consumers, and some can be toxic or potentially carcinogenic. It is for this reason that they are regulated. In 2008 the EU published a new regulation that contains two lists of these compounds. The first list contains 15 banned flavorings, and the second list 10 compounds with stipulated limits.</p>
<p>A method was developed using automated headspace solid-phase microextraction coupled with GC-MS/MS to simultaneously determine the presence of seven biologically active flavoring substances whose levels of use in processed foods is controlled by statutory limits.</p>
<p>The method has been optimized and validated for three different generic food types categorized on the basis of composition and anticipated use levels of flavorings and food ingredients. The food categories are alcoholic and non-alcoholic beverages; semi-solid processed foods (e.g., soups, sauces, confectionery, etc.); and solid foods (muesli, bakery products, etc.). The method is simple, inexpensive, and rapid, and eliminates the use of flammable and toxic solvents. There is no sample preparation, and using SRM, unequivocal confirmation of identification is achieved even in highly complex matrices containing many potentially interfering volatiles.</p>
<h3><strong>What will you learn?</strong></h3>
<p>In this informative webinar, we will explain how to optimize and validate a simple, inexpensive, and rapid method to confirm and identify biologically active flavorings using automated headspace solid-phase micro-extraction coupled with GC-MS/MS.</p>
<blockquote>
<p><strong>Presenter: Dr Elena Ciceri</strong></p>
</blockquote>
<blockquote>
<p>joined Thermo Fisher Scientific in 2007. She has been actively involved in various roles at the organization with a focus on research and development. She is the author of several Application Notes and Technical Notes, which range from determination of contaminants in environmental samples to validation/authentication of food and beverage samples. As an analytical chemist she has vast expertise in troubleshooting skills and solving customer’s analytical challenges. Elena Ciceri received her PhD in Chemistry from the University of Insubria, Italy.</p>
</blockquote>


Pixabay/Tim Toomey: Direct Analysis of Food and Beverages using SPME-GC-MS/MS – No Sample Cleanup, Automated and Highly Specific

Direct Analysis of Food and Beverages using SPME-GC-MS/MS – No Sample Cleanup, Automated and Highly Specific

<h5><strong>The advantages of TF-SPME as an extraction technique will be discussed using the following examples:</strong></h5>
<ul>
<li>Comparing off-flavor chemicals in beer by sequential-SBSE and TF-SPME</li>
<li>Analysis of vegetable oils by HS-TF-SPME</li>
<li>Chemicals in vaping products by HS-TF-SPME</li>
<li>Analysis of free and glycosidically bound volatile phenolics in smoke-tainted wines.</li>
</ul>
<h5><strong>By attending this presentation you will learn:</strong></h5>
<ul>
<li>about the advantages of TF-SPME sample preparation for GC-MS, including sensitivity, ease of use, versatility, and precision</li>
<li>how one sample preparation technique does not always work best for all sample types and analytes</li>
<li>how with GERSTEL thermal desorption instrumentation, selecting the most appropriate extraction technique from many options is possible.</li>
</ul>
<blockquote>
<p><strong>Presenter: Ray Marsili (Marsili Consulting Group, Rockford, Illinois, USA)</strong></p>
</blockquote>
<blockquote>
<p>Ray has published over 30 journal papers on food and flavor chemistry. He has edited four books on flavor, fragrance and odor analysis <em>Techniques for Analyzing Food Aroma (1997); Flavor, Fragrance and Odor Analysis (2002); Sensory-Directed Flavor Analysis (2006) and Flavor, Fragrance and Odor Analysis, 2nd Ed. (2012)</em>. He has 35 years&#39; experience as an R&amp;D analytical laboratory manager/flavor chemist for major national and international food and ingredient companies. Today, he is an independent analytical flavor consultant, with a laboratory at Rockford University, Rockford, Illinois, USA.</p>
</blockquote>


Gerstel: Advantages of TF-SPME Sample Extraction Prior to GC-MS

Advantages of TF-SPME Sample Extraction Prior to GC-MS

<p><strong>There is increased concern regarding the authenticity of basmati rice throughout the world. For years, traders have been passing off a lesser quality rice as the world&#39;s finest long-grained, aromatic rice, basmati, in key markets like the US, Canada and the EU.</strong></p>
<p>In this on-demand webinar, we describe a proof of principle method to assess the authenticity of basmati rice using the latest advancements in high resolution GC-MS and informatics technologies. Volatile compounds of interest were extracted from heated dry rice via SPME and headspace. Following a generic GC separation, detection was performed using a SYNAPT G2-Si MS run in HDMSE mode. Collection of a HDMSE dataset offers a high level of specificity owing to the orthogonal nature of the ion mobility separation to the GC separation.</p>
<p>Progenesis QI, the latest OMICS informatics package from Waters, is designed to utilize the 4-dimensional data produced during a SYNAPT G2-Si HDMSE acquisition. Initially, alignment of all injections was performed followed by the unique peak co-detection process resulting in the same number of analyte measurements in every sample and no missing values. Data from all isotopes and adducts of a parent compound were then deconvoluted giving a single robust and accurate quantitative measurement for that parent compound. The peak picking and deconvolution algorithms ensure a high quality compound table where adducts and isotopes are grouped with the parent m/z. Compounds of interest from the rice samples were highlighted using various multivariate statistical techniques such as PCA and identified using elucidation tools and relevant database searches within the software platform.</p>
<p>This workflow has general applicability to many areas of discovery OMICS and food research where biomarkers differentiating between two or multiple groups are required.</p>
<h3><strong>What will I learn?</strong></h3>
<ul>
<li>An experimental workflow to evaluate the authenticity of foodstuffs</li>
<li>A basic workflow for the discovery of volatile biomarkers between multiple groups of samples</li>
<li>The basics of HDMSE data independent acquisition</li>
<li>How Progenesis QI is used to analyze metabolomics data</li>
</ul>
<h3><strong>Who should attend?</strong></h3>
<ul>
<li>Food research scientists</li>
<li>Metabolomics research scientists</li>
<li>Biomarker research scientists</li>
</ul>
<blockquote>
<p><strong>Presenter: Robert Tonge, Ph.D. (Senior Product Manager, OMICS Informatics, Waters Corporation)</strong></p>
</blockquote>
<blockquote>
<p>Dr Robert Tonge is Senior Product Manager for OMICS Informatics at Waters Corporation, Manchester UK. Robert has been at Waters for 4 years in both Product Development and Field Marketing and has approaching 20 years experience in OMICS science. He trained initially in Biochemistry and Toxicology before moving to &#39;Big Pharma&#39; where he worked in Discovery and Translational Research across a wide variety of disease areas from cancer, cardiovascular disease and infection research.</p>
</blockquote>
<blockquote>
<p><strong>Presenter: Gareth Cleland, Ph.D. (Principal Scientist, Food &amp; Environmental Business, Waters Corporation)</strong></p>
</blockquote>
<blockquote>
<p>Dr Gareth Cleland is a Principal Scientist within the Food and Environment Business Operations at Waters Headquarters, USA. Following his Chemistry studies, he started his professional career working as a Development Chemist for a small coatings company in Oxfordshire, UK. He joined Waters Corporation in 2002 and has held various roles within the organization, both UK and US based, over the last 12 years.</p>
</blockquote>


Pixabay/Trung Hieu Dang: Discovery OMICS and Progenesis QI for Food Authenticity Testing

GCMS webinars focusing on SPME - page 7