<p><strong>The human body is the most sophisticated atomic engineer. This idea underpins a breakthrough technology developed by an international research team led by scientists from the Czech Advanced Technology and Research Institute (CATRIN) at Palacký University Olomouc and the Centre for Energy and Environmental Technologies (CEET) at VSB – Technical University of Ostrava. By drawing inspiration from the way enzymes function in the human body, the researchers have created a novel material that could fundamentally change the industrial production of hydrogen peroxide and other important chemicals. The new approach simplifies the production process, eliminates the need for toxic organic solvents and expensive precious metals, and requires only sunlight, oxygen and water to operate. The results </strong><a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-025-67189-3"><strong>were published by the prestigious journal </strong><i><strong>Nature Communications</strong></i></a><strong>, which ranked the study among the 50 most significant scientific discoveries of the year.</strong></p><p>Hydrogen peroxide is one of the most important industrial chemicals. It is widely used not only in the chemical industry but also in pharmaceuticals, medicine, the textile industry and water-treatment technologies. The global hydrogen peroxide market is estimated to exceed USD 5 billion annually. Conventional production involves a multistep process that relies on toxic organic solvents and costly palladium-based catalysts. In addition, both the starting chemicals and the resulting waste products can have negative impacts on human health and the environment.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Cesti_vedci_vyvinuli_material_pro_vyrobu_chemikalii_z_vody_a_slunce_Inspirovali_se_lidskymi_enzymy_2_c4d5ecbafb.webp" alt="CATRIN: Czech scientists develop a material for producing chemicals from water and sunlight, inspired by human enzymes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Cesti_vedci_vyvinuli_material_pro_vyrobu_chemikalii_z_vody_a_slunce_Inspirovali_se_lidskymi_enzymy_2_c4d5ecbafb.webp 208w," sizes="100vw" width="1600" height="1200"></p><p><i>“Our aim was to develop a material that enables the efficient, environmentally friendly and affordable production of hydrogen peroxide. When designing this photocatalyst, we were inspired by the structure and behaviour of enzymes in the human body. The result is a technology that does not require toxic organic solvents or expensive precious metals and instead uses a low-cost material based on carbon, nitrogen and copper. It operates in water using only sunlight and oxygen from the air,”</i> said<strong> Radek Zbořil, leader of research teams at CATRIN and CEET</strong>.</p><p>In developing the new photocatalyst, the Czech scientists mimicked the function of cytochrome c oxidase—an enzyme that enables human cells to obtain energy by transferring electrons to oxygen. This process relies on copper atoms embedded in the enzyme’s structure, and it was precisely this mechanism that the researchers sought to reproduce.</p><p><i>“We very precisely replicated the chemical environment of metals within the enzyme’s structure and anchored copper atoms onto the surface of extremely small carbon nanoparticles with photocatalytic properties. When exposed to light, highly efficient electron transfer occurs between the carbon nanoparticles, the copper atoms and oxygen molecules. This process closely resembles an enzymatic reaction and enables high hydrogen peroxide production,”</i> explained the first author of the study, <strong>Lukáš Zdražil, who is affiliated with both CATRIN and CEET</strong>.</p><p>Producing hydrogen peroxide using sunlight and water has been a long-standing goal of research teams worldwide, as it eliminates the use of toxic organic solvents and avoids the formation of hazardous by-products. Until now, however, research in this area has largely remained at an academic level, mainly due to the use of noble metals and often complex photocatalyst designs. Laboratory studies have also resulted in relatively low hydrogen peroxide yields, which could not compete with existing industrial processes.</p><p><i>“<strong>The new photocatalyst achieves hydrogen peroxide production rates up to two orders of magnitude higher than all previously reported systems</strong>, bringing us much closer to industrial requirements. In addition, the material is completely non-toxic, easily recyclable and reusable,”</i> added Zdražil.</p><p>The Czech teams are now focusing on potential applications of this technology in decentralised production units. Such systems could enable efficient, local production of hydrogen peroxide, for example for use in agriculture, pharmaceutical manufacturing or environmental applications. The combination of solar energy and materials inspired by enzymatic systems may also lead to further promising advances.</p><p><i>“I believe that mimicking the structures and functions of iron- and copper-based enzymes could pave the way for other innovative technologies in the chemical industry and pharmaceuticals, such as the production of epoxides, alcohols or phenols,”</i> concluded Zbořil.</p>

 Czech scientists develop a material for producing chemicals from water and sunlight, inspired by human enzymes

<p><strong>🎤 Presenter:</strong> Sarah C. Foster (William &amp; Mary)</p><p>💾 <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbFk5RFV6cGdVaThIVjRSQ0N3OVFkdzE5d2Y0QXxBQ3Jtc0trUHhzWGtLeTNKcFVhelU3X1E3U3A4Z1ZHUDBkME02MDl1ajk1QnpFc25ka3ZKUlhKOFVOdDZocnAwTEZZOTZEUE84cWJTUEVUVjgyY0FvT2xBcmpkenVYOVJTd3d0a1pQNVJkSENfZXFsVmF0dF9rMA&amp;q=https%3A%2F%2Fgcms.labrulez.com%2Flabrulez-bucket-strapi-h3hsga3%2FO_2_Foster_04b38f9b88.pdf&amp;v=e5w4zwhBzRY"><strong>PDF presentation</strong></a></p><h3><strong>Abstract</strong></h3><p><strong>Fermentation is a byproduct of microbial metabolism. When beverages become fermented, the microorganisms involved produce volatile organic compounds (VOCs). It is important to examine the VOC profile of fermented beverages to understand their consumer perception and health considerations. Traditionally, VOCs are detected by gas chromatography-mass spectrometry (GC-MS). However, more complex matrices, like fermented products, benefit from the enhanced separation of comprehensive two-dimensional gas chromatography (GC×GC). This study aimed to develop an understanding of the VOCs related to different fermented beverages through a nontargeted lens via comprehensive two-dimensional gas chromatography with dual detection using flame ionization detection and time-of-flight mass spectrometry (GC×GC-FID/TOFMS).&nbsp;</strong></p><p>Data analysis focused on developing a complete VOC profile of fermented products. Moreover, analysis aimed to identify differentiating VOCs to understand differences between products and distinguish the drink matrix from the microbial matrix. Results indicate that it is possible to attribute VOCs to one component of a complex sample, creating a microbial VOC profile and a base VOC profile. It was possible to discern products from one another, including contaminated products from non-contaminated products. Data visualization consisted of Principal Component Analysis (PCA) scores and loadings plots, bar chats, Hierarchical Cluster Analysis (HCA), and Partial Least Squares Discriminant Analysis (PLS-DA). Data analysis software was capable of processing and aligning samples with high levels of biological variation, making GC×GC a promising analytical tool for market research and regulation. Future studies will aim to correlate VOCs detected via GC×GC-FID/TOFMS to the microbial genetics of fermented products.</p><h3><strong>Video Transcription</strong></h3><h4><strong>1. Introduction</strong></h4><p>Sarah Foster introduces research focused on the application of comprehensive two-dimensional gas chromatography (GC×GC) for analyzing fermented beverages.</p><p>The laboratory primarily uses <strong>GC×GC</strong> for:</p><ul><li>Separation and identification of volatile organic compounds (VOCs)</li><li>Applications in forensic sciences and food sciences</li></ul><h5><strong>Forensic Applications</strong></h5><ul><li>Fingerprint residue</li><li>Gunshot residue</li><li>Pepper spray</li><li>Other trace evidence</li></ul><h5><strong>Food Science Applications</strong></h5><ul><li>Fermented beverages</li><li>Foods claiming health benefits</li></ul><p>An additional focus of the lab is transitioning GC×GC from proof-of-concept research toward real-world field applications, including improved data interpretation and presentation.</p><h4><strong>2. Challenges in Non-Targeted GC×GC Data</strong></h4><p>Working with complex, non-targeted datasets presents several challenges:</p><ul><li>Resolution of complex coelutions</li><li>Increased number of detectable features</li><li>Expansion of compound classes</li><li>Detection of low-level analytes previously masked by abundant compounds</li><li>Difficulty in longitudinal tracking due to increased data complexity</li></ul><p>While GC×GC reveals more chemical information, interpreting this data becomes more demanding.</p><h4><strong>3. Data Processing and Statistical Tools</strong></h4><h5><strong>Software Used</strong></h5><ul><li><strong>ChromaTOF</strong> – for single chromatogram peak detection and deconvolution</li><li><strong>ChromaTOF Sync 2D</strong> – alignment software for entire datasets</li><li><strong>R statistical software</strong> – for multivariate visualization<ul><li>vegan package</li><li>ComplexHeatmap package</li></ul></li></ul><h5><strong>Advantages of Sync 2D</strong></h5><ul><li>Performs peak detection and deconvolution across all chromatograms simultaneously</li><li>Generates a unified peak table for entire datasets</li><li>Facilitates trend analysis</li></ul><h5><strong>Dimensionality Reduction Techniques Used</strong></h5><ul><li>Principal Component Analysis (PCA)</li><li>Principal Coordinate Analysis (PCoA)</li><li>Hierarchical Cluster Analysis (HCA)</li></ul><p>Each data point includes:</p><ul><li>Primary retention time</li><li>Secondary retention time</li><li>Signal intensity</li></ul><h4><strong>4. Statistical Approaches Explained</strong></h4><h5><strong>PCA (Principal Component Analysis)</strong></h5><ul><li>Uses Euclidean distance</li><li>Assumes linear variance structure</li><li>Clustering based on shared analytes</li><li>Identifies key analytes driving variance</li><li>Loadings plots explain separation patterns</li></ul><h5><strong>PCoA (Principal Coordinate Analysis)</strong></h5><ul><li>Uses non-Euclidean dissimilarity (e.g., Bray–Curtis)</li><li>Emphasizes compositional differences</li><li>Better for non-linear variance structures</li></ul><h5><strong>HCA (Hierarchical Cluster Analysis)</strong></h5><ul><li>Uses Euclidean dissimilarity (in this study)</li><li>Clustering based on:<ul><li>Presence/absence</li><li>Relative abundance</li></ul></li><li>Output: dendrogram<ul><li>Short branches = more similar</li><li>Long branches = more dissimilar</li></ul></li></ul><h4><strong>5. Research Goals</strong></h4><ul><li>Apply GC×GC-TOFMS for volatile analysis and aroma profiling of mead</li><li>Investigate impact of:<ul><li>Yeast strain</li><li>Honey concentration</li></ul></li><li>Use a non-targeted analytical approach</li><li>Extract and compare chemical features across samples</li></ul><h4><strong>6. Mead Production Overview</strong></h4><p>Mead is produced by fermenting honey with filtered water. Fruits or spices may be added. It may also be barrel-aged.</p><h5><strong>Experimental Design (Silverhand Meadery Collaboration)</strong></h5><ul><li>1-gallon batches</li><li>5 yeast strains</li><li>3 honey concentrations:<ul><li>1.5 lb/gal (low alcohol, expected dry finish)</li><li>3 lb/gal (standard)</li><li>5 lb/gal (high alcohol, expected sweet finish)</li></ul></li></ul><h5><strong>Yeast Strains Tested</strong></h5><ul><li><strong>Kveik Voss</strong> – neutral with citrus notes</li><li><strong>Munich</strong> – banana, clove (esters &amp; phenols)</li><li><strong>EC1118</strong> – neutral (sparkling wine yeast)</li><li><strong>D47</strong> – tropical/white floral</li><li><strong>Abbaye</strong> – temperature-dependent:<ul><li>Low temp: banana, tropical, spicy</li><li>High temp: raisin, fig</li></ul></li></ul><p>Fermentation lasted 9 months. Stabilizers were added post-fermentation.</p><h4><strong>7. Sample Preparation</strong></h4><h5><strong>Mead Samples</strong></h5><ul><li>3 mL in 20 mL headspace vial</li><li>0.5 g salt</li><li>5 µL (500 ppm) 1-decanol internal standard</li></ul><h5><strong>Honey Samples</strong></h5><ul><li>1.5 g honey + 1.5 mL water</li><li>Salt + internal standard</li></ul><h5><strong>Water Controls</strong></h5><ul><li>3 mL water + salt + internal standard</li></ul><p>All samples were vortexed and analyzed by GC×GC-TOFMS.</p><h4><strong>8. Instrumentation</strong></h4><p>Instrument: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=24&amp;search=Pegasus+BTX+4D"><strong>LECO Pegasus BTX 4D GC×GC-TOFMS</strong></a></p><p>Features:</p><ul><li>Dual TOFMS and FID detection</li><li>Reverse fill/flush modulator</li><li>Flow splitter</li></ul><p>The modulator:</p><ul><li>Fills loop in forward direction</li><li>Flushes to secondary column</li><li>High secondary flow split between TOFMS and FID</li></ul><h4><strong>9. Initial Observations</strong></h4><p>Key compounds identified:</p><ul><li>Furfurol (heated honey marker)</li><li>2-ethylhexanol (water)</li><li>3-methylbutanol (fermentation product)</li><li>Benzaldehyde (fermentation product)</li></ul><p>Total detected: <strong>96 volatile organic compounds</strong></p><h4><strong>10. Multivariate Results</strong></h4><h5><strong>PCA Findings</strong></h5><ul><li>Four groupings largely dictated by honey concentration</li><li>1.5 lb/gal group clustered together</li><li>3 lb/gal group tightly clustered</li><li>5 lb/gal showed pattern similar to 1.5 lb/gal</li><li>Abbey yeast formed a distinct cluster</li></ul><h5><strong>PCoA Findings</strong></h5><ul><li>Similar overall patterns</li><li>Abbey yeast more distinctly separated</li><li>Likely due to Bray–Curtis dissimilarity emphasizing compositional differences</li></ul><h5><strong>HCA + Heatmap Findings</strong></h5><ul><li>Clustering aligned with PCA/PCoA trends</li><li>Abbey yeast again formed distinct grouping</li><li>Appeared to contain similar compounds but in lower relative abundances</li></ul><p>Two major overall clusters:</p><ul><li>1.5 lb/gal group</li><li>All other meads</li></ul><h4><strong>11. Compound Trends vs Honey Concentration</strong></h4><p>Observed correlations:</p><ul><li><strong>Ethyl lactate</strong>: increased with honey concentration</li><li><strong>Furfurol</strong>: increased with honey concentration</li><li><strong>3-methylbutanol</strong>:<ul><li>Decreased with honey concentration (except Abbey strain)</li></ul></li><li><strong>Ethyl octanoate</strong>:<ul><li>Highest at 3 lb/gal</li><li>Lowest at 1.5 lb/gal</li><li>Intermediate at 5 lb/gal</li></ul></li></ul><p>Abbey strain showed unique behavior, possibly explaining its distinct clustering.</p><h4><strong>12. Conclusions</strong></h4><ul><li>GC×GC-TOFMS is highly effective for aroma profiling of mead</li><li>Dimensionality reduction techniques successfully highlighted relationships between samples</li><li>Honey concentration strongly influences volatile profile</li><li>Yeast strain (especially Abbey) significantly impacts composition</li></ul><h4><strong>13. Future Work</strong></h4><ul><li>Investigate microbial environment effects on VOC production</li><li>Link microbial kinetics data to volatile profiles</li><li>Explore compound-class-specific trends</li></ul><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote>

Application of GC×GC for the investigation of fermented beverages (Sarah C. Foster, MDCW 2026)

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 16th February 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you technical note by <strong>Agilent Technologies, </strong>presentation by<strong> MDCW / C³AL </strong>and<strong> </strong>application notes by<strong> BaySpec </strong>and<strong> Shimadzu!</strong></p><h3><strong>1. Agilent Technologies: Why Do Loss of Resolution and Retention Time Shift Occur After Installing a New GC Column?</strong></h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/te_loss_resolution_retention_time_shifts_gc_column_5994_8773en_agilent_e5e79a5f5e.pdf"><strong>Full PDF for download</strong></a></li></ul><p>When a new column is installed on an instrument that has been running an application for a long time, and all the instrument parameters are set to the same values as before, the resolution between a pair of critical analytes can drop unacceptably, creating concern that the column is defective.&nbsp;</p><p>The chromatograms that accompany columns like these will show that the retention times of the poorly resolved peaks on the new column have shifted. This difference indicates a change in linear velocity of the carrier gas, since the run conditions were the same.&nbsp;</p><p>Why did the retention times of those compounds shift under seemingly identical run&nbsp;conditions? The answer is that the run conditions are not identical because the columns are not truly identical. In any manufacturing process, products are built to tolerances. In the case of a GC capillary column, these tolerances include diameter and length. Even small differences in diameter and length will affect the actual velocity and flow rate through a column at a given head pressure.</p><h3><strong>2. BaySpec: Illicit Drug Detection &amp; Identification Using the Continuity™ Field Portable Mass Spectrometer</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Bay_Spec_App_Note_C101_Illicit_Drug_Detection_1_5bd32f3fe9.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The trafficking and abuse of illicit drugs inflict tremendous harm upon individuals, families, and communities throughout the United States and the world. Based on the report of the United Nations Office on Drugs and Crime, nearly 296 million people worldwide used drugs in 2022, with an estimated 64 million suffering from drug use disorders. The opioid epidemic alone has claimed over 160,000 lives in the United States over the past two years, highlighting the urgent need for effective measures to combat this scourge.</p><p>Traditional methods of drug detection, such as laboratory-based analysis, are often time-consuming, costly, and require specialized personnel. These limitations make it challenging to address the rapid and widespread nature of drug trafficking and abuse. Moreover, the constant evolution of synthetic drugs and new psychoactive substances poses a significant challenge for law enforcement and public health officials, as these substances often evade detection using conventional methods.&nbsp;</p><p>In recent years, portable mass spectrometry has emerged as a promising solution for the rapid detection and identification of illicit drugs. Unlike traditional laboratory instruments, portable mass spectrometers offer the advantage of on-site analysis, enabling law enforcement officers and first responders to quickly identify substances in real-time. This technology can be deployed in various settings, including border checkpoints, public events, and field investigations, providing a versatile and efficient tool for combating drug-related crimes. As the opioid crisis and the rise of synthetic drugs continue to pose significant challenges, the integration of portable mass spectrometry into drug detection strategies represents a critical step towards a safer and healthier society.</p><h4><strong>Instrumentation&nbsp;</strong></h4><p><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2218"><strong>BaySpec Continuity™ Portable Mass Spectrometer</strong></a> was used equipped with a Swab-APCI source, specifically designed for TSA-approved swabs. The samples on swabs were converted into vapors via the Swab vaporizer unit, which then were drawn into the ionization chamber by the built-in sampling pump.</p><h4><strong>Conclusions&nbsp;</strong></h4><p>In this study, we demonstrated the use of the Continuity™ Field Portable Mass Spectrometer equipped with a SwabAPCI ionization source for the detection and identification of various drugs. The capabilities of the instrument were assessed through the creation of calibration curves and surface sampling experiments using ten drug standards and four selected analytes: fentanyl, cocaine, methamphetamine, and MDMA. By serial diluting these standards in methanol, we established calibration curves and determined the instrument’s Limits of Detection (LODs) in MS2 mode. These experiments highlighted the instrument’s ability to detect trace amounts of drugs with high sensitivity and specificity.&nbsp;</p><p>The performance of the Continuity™ field portable mass spectrometer in both controlled and real-world scenarios underscores its potential as a rapid, on-site analytical tool. The results obtained from triplicate measurements reinforce the reliability of this method, making it a valuable asset for law enforcement and public health agencies in their efforts to combat drug-related issues. This study confirms that the portable MS system can quickly and effectively identify illicit substances, offering a practical solution for field investigations and real-time decision-making. As the landscape of illicit drug use continues to evolve, such advancements in portable analytical technology will be crucial in providing timely and accurate information for intervention and prevention strategies.</p><h3><strong>3. MDCW / C³AL: COUNTING DOUBLE BONDS: GC×GC–FID FOR PLASTIC PYROLYSIS OILS</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_26_Petr_Vozka_04ef50f601.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The presentation focuses on the analytical challenge of accurately quantifying olefins (double bonds) in plastic pyrolysis oils and alternative fuels derived from plastic waste. As chemical recycling processes such as pyrolysis and hydrothermal processing gain importance, detailed compositional analysis becomes essential. Pyrolysis oils are highly complex mixtures containing paraffins, iso-paraffins, olefins, cycloalkanes, aromatics, and multi-ring structures. Because olefin content strongly affects fuel stability and upgrading requirements, reliable quantification is critical.</p><p>Traditional bulk methods such as bromine number, bromine index, iodine value, FTIR, Raman, and NMR provide only total unsaturation and often suffer from interferences or limited selectivity. To achieve detailed group-type and compound-level analysis, the authors apply comprehensive two-dimensional gas chromatography with flame ionization detection (GC×GC–FID). This technique delivers high resolution, reduces co-elution, and enables classification of linear, branched, cyclic, and aromatic olefins across wide boiling ranges.</p><p>To further improve quantitative accuracy, a selective adsorption approach using silver-modified silica (Ag–SiO₂) solid-phase extraction is introduced. Olefins are selectively retained, and comparison of GC×GC–FID chromatograms before and after adsorption allows precise determination of olefin content. This method is shown to be cost-effective and reliable for samples containing more than 5 wt% olefins.</p><p>Additionally, the presentation explores chemical derivatization of olefins using dimethyl disulfide (DMDS) and other disulfides to improve structural identification and quantification. While effective for lighter gasoline-range samples, challenges remain for heavier fuels such as jet and diesel fractions. Ongoing work focuses on testing heavier disulfides, optimizing reaction conditions, and validating results using ¹H NMR spectroscopy and future TOFMS analysis.</p><h3><strong>4. Shimadzu: Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) in Tattoo Inks Using GC-MS</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_09_ssk_023_en_ff47795f55.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li>&nbsp;GCMS-QP2020 NX supports effective analysis of PAHs in Tattoo inks.</li><li>It provides an MFDS-based GC-MS method for PAHs in tattoo inks, enabling compliance with Korean regulations.</li></ul><p>Tattoo inks have been utilized for diverse purposes throughout history, serving as cultural identifiers and means of personal expression. In contemporary society, tattooing extends beyond aesthetics and self-expression to include medical applications such as camouflage of scars and post-operative rehabilitation. Because these inks are injected directly into the dermal layer, rigorous safety and hygienic control are essential to ensure human health protection.&nbsp;</p><p>Among the regulated constituents in tattoo inks, polycyclic aromatic hydrocarbons (PAHs) are of particular concern. PAHs comprise over a hundred structurally related compounds, commonly generated through incomplete combustion processes, vehicle exhaust, and tobacco smoke. Several PAHs have been classified as carcinogenic, and chronic exposure may lead to bioaccumulation and subsequent adverse health effects.&nbsp;</p><p>In January 2022, the European Union implemented stringent restrictions through updated REACH regulations, limiting the presence of approximately 4,000 hazardous substances in tattoo and permanent make-up inks, including PAHs. 1) These regulations prohibit the use of carcinogenic, mutagenic, and sensitizing substances previously detected in such products. Since the enforcement date, only compliant inks are permitted for distribution and use within the EU.&nbsp;</p><p>In South Korea, tattoo inks were regulated as consumer chemical products under the Ministry of Environment until June 2025. Due to increasing safety concerns, they have since been reclassified as sanitary products under the authority of the Ministry of Food and Drug Safety (MFDS), resulting in the implementation of more stringent safety requirements. 2)&nbsp;</p><p>This application news introduces the analytical methodology for quantification of PAHs in tattoo inks based on the MFDS regulatory standards (Notice 2025-36). Samples were prepared in accordance with the prescribed protocol, and PAH concentrations were determined using gas chromatography– mass spectrometry (GC-MS) in selected ion monitoring (SIM) mode.</p><h4><strong>Analytical Conditions&nbsp;</strong></h4><p>For the determination of PAHs in tattoo inks, a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-QP2020+NX"><strong>GCMS-QP2020 NX</strong></a> system was employed, as shown in Figure 1. The instrumental parameters and selected ion monitoring (SIM) conditions used for PAH analysis are summarized in Table 1.</p><h4><strong>Conclusions</strong></h4><p>Quantitative analysis of PAHs in tattoo inks was performed using the GCMS-QP2020 NX. Sample preparation followed the procedure outlined in the MFDS ‘Standards and Specifications for Sanitary Products.’ All eight PAH analytes showed excellent linearity, with correlation coefficients (R²) exceeding 0.999. Recovery tests showed values between 81.6% and 115.1%, with relative standard deviations (%RSD) ranging from 0.11% to 3.13%, demonstrating good accuracy and precision. These results confirm that the GCMS-QP2020 NX is a suitable instrument for PAH analysis in tattoo inks.</p>

News from LabRulezGCMS Library - Week 08, 2026

Article

Application

Video

Presentation

Science and research

The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography Workshop

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

CATRIN

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Agilent Technologies

Organomation

Milestone

Thermo Fisher Scientific

Shimadzu Corporation

<p><strong>Join us for an exciting launch as SepSolve Analytical and Shimadzu Asia Pacific unveil their new collaboration to deliver GCxGC–TOF MS solutions to the Asia Pacific region. In non-targeted screening of complex samples, every detail matters. Misidentifying compounds can lead to costly errors and wasted time. Unfortunately, conventional one-dimensional GC–MS struggles to fully resolve the complex chemical compositions found in petrochemical, food, and biological matrices. Frequent co-elution often result in low-confidence identifications or missed compounds altogether.</strong></p><p>This webinar will provide an overview of how GCxGC–TOF MS addresses these challenges with enhanced separation, reliable compound identification, and advanced data analysis tools — enabling researchers to gain detailed insights with a new level of efficiency.</p><p>Don’t miss this opportunity to experience the future of non-targeted screening and explore how GCxGC-TOF MS can elevate your research! shimadzu gc/ms</p><p><strong>Learning Objectives:</strong></p><ul><li>Understand the benefits of GC×GC and the advantages of both flow and thermal modulation to upgrade Shimadzu Nexis GC-2030 to GC×GC capability</li><li>Discover the benefits of BenchTOF2 mass spectrometers for high sensitivity, confident identification, and user-friendly workflows</li><li>Learn how chemometric data analysis can automatically identify key features that distinguish between complex samples</li><li>See real-world applications, from analysis of sustainable fuels, to aroma profiling of food and beverages and essential oil comparisons</li></ul><blockquote><p><strong>Presenter: </strong>Laura McGregor (Product Marketing Manager, SepSolve Analytical)</p><p>Laura McGregor completed a Ph.D. in Environmental Forensics at the University of Strathclyde in 2012. Her research interests included the chemical fingerprinting of coal tar contamination using GC×GC–TOF MS. In her current role at SepSolve Analytical, she oversees marketing activities for the full product portfolio and specialises in applying GC×GC and chemometrics to challenging samples.&nbsp;</p><p><strong>Presenter:&nbsp;</strong>Jackie (Assistant Product Manager GC &amp; GCMS, Shimadzu, Asia Pacific, Pte Ltd)</p><p>Jackie obtained his PhD in Analytical Chemistry from the National University of Singapore, He has garnered over 10 years of research, training, and facilitation experience. Jackie meets scientists from various industries to share technical knowledge and collect feedback, understanding their problems and helping them find well-suited solutions in GC-related analyses.</p><p><strong>Presenter:&nbsp;</strong>Anthony Buchanan (Portfolio Product Manager, SepSolve Analytical)</p><p>Anthony Buchanan received a master’s degree in Analytical Toxicology at King’s research contract labs using GC–MS. He joined SepSolve in 2018 as an Application Engineer and then Service Engineer, before becoming the Portfolio Product Manager for the GCxGC and TOF mass spectrometry technologies in 2022.</p></blockquote>

Shimadzu corporation: Enhancing Non-Targeted Screening In Challenging Matrices

Enhancing Non-Targeted Screening In Challenging Matrices

Don’t miss this opportunity to experience the future of non-targeted screening and explore how GCxGC-TOF MS can elevate your research!

<p><strong>This live panel discussion brings together experts from IDA and Agilent to explore market trends, quality assessment, and challenges in dairy testing. Key topics include detecting contaminants, ensuring regulatory compliance, and maintaining product quality.</strong></p><p><strong>The panel will discuss advanced technologies for testing adulteration, pesticides, and heavy metals, and share tips on improving workflows and aligning with regulations. Attendees will also have the opportunity for live interaction with the panelists.</strong></p><blockquote><p><strong>Presenter: </strong>Prof. (Dr) J. B. Prajapati (Chairman, Indian Dairy Association (West Zone))</p><p>Professor (Dr.) Jashbhai B. Prajapati is a veteran Dairy Professional with 45 years of experience in research, teaching and professional manpower development. He is a technology graduate from Anand and Ph.D from NDRI and retired as Dean of the Faculty of Dairy Science, AAU, Anand. He worked as the Chairman of Verghese Kurien Centre of Excellence at IRMA and now the Chairman of IDA (West Zone). He is Vice President of National Academy of Dairy Science (India) apart from being member in several professional bodies. He is associated with FSSAI, NADSI, NDDB, IDF, Gut microbiota Foundation, SASNET and many other organizations. His core area of research is probiotics and functional dairy foods and he is the first Indian scientist to have deposited and whole genome sequenced two Indian probiotic cultures at IMTech, Chandigarh as the Indian Patent deposits. He is a well-travelled scholar with more than 500 publications.</p><p><strong>Presenter:&nbsp;</strong>Dr. Satish Kulkarni (Chairman, Indian Dairy Association (South Zone))</p><p>Dr. Satish Kulkarni earned both his Dairy Diploma and Doctoral degree in Dairy Technology from the National Dairy Research Institute (NDRI), Karnal/Bangalore. He conducted post-doctoral research in Germany for three years. As a scientist, he has guided numerous students at the master’s and doctoral levels.</p><p>Dr. Kulkarni has been honoured four times by the ICAR for team research and received the Best Teacher Award in 2008. He served as the Head of NDRI, Bangalore, from 2008 to 2015. Currently, he is a practicing advocate specializing in food law and works as a food regulatory consultant. He is the founder-partner of Dairy Skills &amp; Food Quality Academy and Legalwrax Business Solutions, Bangalore. Dr. Kulkarni has also served as the President of AFSTI, Mysore, Vice President of IDA, New Delhi, and is currently the Chairman of IDA (South Zone).</p><p><strong>Presenter:&nbsp;</strong>Dr. Rajesh Nair (Dy. Managing Director, NDDB - CALF Ltd.)</p><p>Dr. Rajesh Nair is currently working as Dy. Managing Director at NDDB CALF LTD, Anand, a wholly subsidiary National Dairy Development Board. He has professional experience spanning 30 years in the field of Testing &amp; Inspection of Food &amp; Agricultural products. He has held key leadership positions in several Government, Private and Multinational Companies. He has done his Bachelors, Masters, &amp; Ph.D. in Chemistry.</p><p>He is a member of the Scientific Panel of Method of Sampling and Analysis of FSSAI, a member of a few technical committees of the Bureau of Indian Standards (BIS), standing committee member of Analytical Methods on Additives and Contaminants of IDF. He is also working closely with NABL in different disciplines. He has several publications on Analytical methods and validations of food &amp; Agricultural products and genetic materials in leading scientific journals.</p><p><strong>Presenter:&nbsp;</strong>Mr. Vivek Dhyani (Country Application Solutions Manager, Agilent Technologies India Pvt. Ltd.)</p><p>Mr. Vivek Dhyani is the Application Head and COE Manager at Agilent India. He is responsible for complete demo and Application Engineers’ (AE) management, as well as key workflow development. Prior to this, he served as the Product Manager for GC/GCMS at Agilent India and as a Product Specialist at Agilent Singapore, where he was responsible for technical support for GCMS across Singapore, Indonesia, and South Asia. He has over 20 years of experience in the fields of mass spectrometry and chromatography. Before his current role, he worked at Agilent India as a Product Specialist and Application Engineer for GC/GCMS. Additionally, he was associated with PerkinElmer for more than five years as an Application Specialist for Chromatography and LIMS, providing support to India, neighbouring countries, and the Middle East. Vivek is regularly invited to deliver seminars and training sessions on chromatography by government institutions and private companies.</p><p><strong>Presenter:&nbsp;</strong>Dr. Chandrasekar Kandaswamy (Business Manager, GC/MS, Agilent Technologies India Pvt. Ltd.)</p><p>Dr. Chandra completed his Ph.D. in Chemistry at NIT Trichy. With over 22 years of experience in analytical method development across the food safety, pharmaceutical, and fertilizer industries, he currently serves as a Product Manager for the GC and GCMS portfolio at Agilent. Chandra has extensive expertise in method development and validation. Before joining Agilent in 2009, he worked in various roles within the fertilizer, food, and pharmaceutical sectors. He is passionate about sharing his knowledge and has published six analytical findings in reputed journals. He enjoys engaging with the scientific community and has delivered numerous national and international oral and poster presentations. Outside of work, Chandra loves practicing yoga and spending time with his family.</p><p>The Ph.D. in chemistry from the National Institute of Technology, Tiruchirappalli, is a dedication to education and research. Moreover, his active engagement with the scientific community through numerous national and international presentations, in both oral and poster formats towards commitment to sharing knowledge and fostering dialogue within the field with 10 different journal publications.</p></blockquote>

Agilent Technologies: Panel discussion on improving dairy safety and quality frameworks

Panel discussion on improving dairy safety and quality frameworks

The panel will discuss advanced technologies for testing adulteration, pesticides, and heavy metals, and share tips on improving workflows.

Improving dairy safety and quality frameworks

<div><div id="inner_content_body_text" data-content-id="394785"><p><strong>Join us for an exclusive look into the future of biofoods, where innovation meets sustainability. In this webinar, Dan Merriman from Thermo Fisher Scientific, and Andrew Saarni from Geltor share their expert insights on the transformative role of mass spectrometry (MS) technology in collagen fermentation.</strong>&nbsp;</p><p>Learn how the Thermo Scientific™ Prima PRO Process Mass Spectrometer is setting new standards in biofoods manufacturing, offering unparalleled control, efficiency, and yields.</p><h4><strong>What You Will Learn</strong></h4><ul><li>The critical role of advanced fermentation techniques in biofood production</li><li>How real-time MS monitoring revolutionizes fermentation processes</li><li>Strategies for optimizing manufacturing efficiency and maximizing yields</li><li>Insights into future trends from leading experts in the field</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Professionals in the biofoods industry, bioprocess engineers, and anyone intrigued by the future of food technology will find this webinar invaluable for gaining insights into the next generation of sustainable food production.</li></ul><blockquote><p><strong>Presenter:</strong> Dan Merriman (Senior Advisor, Marketing Process Monitoring, Thermo Fisher Scientific)</p><p>With 35 years of expertise in mass spectrometry and process analytics, Dan will explore the intricacies of collagen fermentation and the impact of MS technology on sustainable food production.</p><p><br><strong>Presenter:</strong> Andrew Saarni (Director of Fermentation, Geltor)</p><p>&nbsp;Andrew brings frontline experience from bio-designed protein production, sharing Geltor's success in implementing advanced bacterial fermentation techniques for high-quality, ethical biofoods.</p></blockquote></div></div>

Thermo Fisher Scientific: Pioneering Collagen Fermentation with Advanced MS Technology

Pioneering Collagen Fermentation with Advanced MS Technology

Insights on the transformative role of mass spectrometry (MS) technology in collagen fermentation. 

<p><strong>In the world of analytical chemistry, efficiency is key. As laboratories strive to enhance their sample preparation processes for GC-MS and LC-MS analyses, one technique stands out: nitrogen blowdown evaporation. This method, which uses a stream of nitrogen gas to dry down liquid samples, has revolutionized the way we concentrate samples post-extraction. Let's dive into how this process can dramatically improve your lab's efficiency, with insights from real-world case studies.</strong></p><p><strong>The Organomation Legacy</strong></p><p>For 65 years, Organomation has been at the forefront of nitrogen evaporator manufacturing. The company's founder, Dr. Neal McNiven, a chemist with a mechanical bent, invented the first commercially successful multiple sample evaporator while working as a researcher at the Worcester Foundation. This innovation set the stage for the advancements we see today.</p><h3><strong>Case Studies: Real-World Impact</strong></h3><h4><strong>University of Cincinnati: From Hours to Minutes</strong></h4><ul><li><strong>The Challenge:</strong> The Department of Chemical &amp; Environmental Engineering needed to dry 10 samples at a time, each with a 5ml starting volume of methanol or acetonitrile, to complete dryness.</li><li><strong>The Solution: </strong>A 12-position N-EVAP nitrogen evaporator.</li><li><strong>The Results:</strong><ul><li>Time reduction: From over 2 hours per sample to just 1 hour for all 10 samples</li><li>Precision improvement: Better control of gas flow to each sample</li><li>Enhanced sensitivity: Ability to evaporate to complete dryness with ease</li></ul></li></ul><h4><strong>University of Chicago: Longevity and Adaptability</strong></h4><p>Dr. Poorna Yalagala's research on DHA's role in brain function showcases the longevity and adaptability of Organomation's equipment:</p><ul><li>Used an N-EVAP for over 15 years</li><li>Recently upgraded to a 24-sample capacity dry bath N-EVAP</li><li>Appreciates the flexibility to fit various test tube sizes</li></ul><h4><strong>Microbac Laboratories: Scaling Up for PFAS Analysis</strong></h4><ul><li><strong>The Challenge: </strong>Need for higher sample capacity within limited benchtop space.</li><li><strong>The Solution:</strong> Transition from N-EVAPs to a MULTIVAP batch evaporator.</li><li><strong>The Benefits:</strong><ul><li>Doubled sample capacity in the same space</li><li>Digital features like thermostat and timer</li><li>400% increase in efficiency for PFAS analysis</li></ul></li></ul><h4><strong>Choosing the Right Evaporator</strong></h4><p><strong>When selecting an evaporator, consider:</strong></p><ul><li>Batch size and total sample volume</li><li>Variety of vial sizes used</li><li>Specific application needs</li></ul><p>For academic settings with diverse protocols, the N-EVAP's flexibility shines. Commercial labs running consistent applications might benefit more from high-capacity batch evaporators like the MULTIVAP.</p><h4><strong>Why Partner with Organomation?</strong></h4><ul><li>Lifetime support at no cost</li><li>Free virtual training for new users</li><li>Money-back performance guarantee</li><li>Some of the longest standard warranties in the industry</li><li>Trusted by industry leaders like Agilent and Waters</li></ul><p>Nitrogen blowdown evaporation is more than just a technique; it's a game-changer for laboratories seeking to optimize their sample preparation processes. Whether you're in academic research or commercial testing, the right evaporator can significantly boost your efficiency, precision, and overall productivity. As we continue to push the boundaries of analytical chemistry, tools like those provided by Organomation will undoubtedly play a crucial role in shaping the future of laboratory science.</p><blockquote><p><strong>Presenter: </strong>David Oliva (General Manager of Organomation)</p><p>One of Oliva’s favorite responsibilities is visiting academic institutions and environmental laboratories around the world. He was named to the 40 Under Forty Class of 2022 from the Worcester Business Journal and is a winner of a B2B Innovator Award from Demand Gen Report.</p></blockquote>

Organomation: Improving Sample Preparation Efficiency - The Power of Nitrogen Blowdown Evaporation

Improving Sample Preparation Efficiency - The Power of Nitrogen Blowdown Evaporation

Learn how nitrogen blowdown evaporation can streamline your GC-MS and LC-MS sample prep. Real case studies show its impact on lab efficiency.

Sample Preparation - Power of Nitrogen Evaporation

<p><strong>Come learn about the considerations, configuration, and results achieved using Gerstel thermal desorption technology with Agilent GC/TQ.</strong></p><blockquote><p><strong>Presenter:</strong> Matthew Curtis (GC/MS Applications Scientist, Agilent)</p><p>Matt joined Agilent in 2013 as a GC/MS applications scientist in the Santa Clara, CA Center of Excellence. His primary responsibility is focused on providing instrument demos for customer interested in each technology Agilent offers; the GC/MS single quadrupole, triple quadrupole and the quadrupole Time-of-Flight. The variety of different samples submitted to the demo lab provide a unique knowledge of optimizing parameters for different applications to provide the best quality data from the instrument.<br>&nbsp;</p></blockquote>

Agilent Technologies: Choose Intelligence

PFAS: Wait! Are You Saying there are PFAS in Air Now?

Come learn about the considerations, configuration, and results achieved using Gerstel thermal desorption technology with Agilent GC/TQ.

<div><div><div><div><div><div><h5><strong>Why is Raman so ideal for the energy industry, including hydrogen and SAF?</strong></h5><p><strong>With its high-resolution compositional data, linear response to concentration, and real-time measurement capabilities, Raman spectroscopy has become an affordable and data-rich alternative to traditional methods of analysis in the energy industry.</strong></p><p>This webinar covers the applications for Raman analysis in two expanding areas of energy production: hydrogen conversion and sustainable aviation fuel.</p><p><strong>Hydrogen:&nbsp;</strong>Hydrogen is growing in popularity as an energy source. Monitoring the conversion process of hydrogen spin isomers from the ortho form to the para form is crucial for efficient hydrogen liquefaction and storage. The speaker covers how Raman analysis can play a pivotal role in providing real-time insights into the hydrogen conversion process to enable improved product quality and process efficiency.</p><p><strong>Sustainable aviation fuel (SAF):&nbsp;</strong>The development of sustainable aviation fuel is an emerging field. Uncover how Raman analysis, specifically with the <strong>Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer</strong>, facilitates in-line material identification and quantification. The speaker will cover how Raman analysis enables faster, safer, and more efficient fuel production.</p><p>Join us to discover the potential of Raman spectroscopy in revolutionizing energy production and shaping a greener tomorrow.</p></div></div></div></div></div></div>

Thermo Fisher Scientific: Leveraging Raman Spectroscopy for Advancements in Energy Production

Leveraging Raman Spectroscopy for Advancements in Energy Production

This webinar covers the applications for Raman analysis in two expanding areas of energy production: hydrogen conversion and sustainable aviation fuel.

Leveraging Raman Spectroscopy in Energy Production

<p><strong>As Shimadzu celebrates 150 years in analytical testing, we highlight what we've learned in cosmetics testing needs: how to get robust reproducibility, improve sensitivity, and manage complex mixtures.&nbsp;</strong></p><p>Our seminar will cover a variety of testing needs, including fragrance analysis and skin sensitization, analysis of regulated UV-adsorbents used in sunscreen products, and heavy metals in items like lipstick, foundation, and eyeshadow. This webinar will be presented in English with an introduction and Q&amp;A in Spanish.</p>

Shimadzu Corporation: Ensuring Beauty is Safe: Shimadzu's Solutions for Cosmetic Product Testing

Ensuring Beauty is Safe: Shimadzu's Solutions for Cosmetic Product Testing

Best practices in cosmetics testing, including fragrance analysis, UV filters, and heavy metals.

Ensuring Cosmetic Safety: Shimadzu Testing Solutions

<div><div><div><p><strong>The increasing use of plastics in our daily lives and in manufacturing processes often culminates in a slow degradation of the materials and the subsequent contamination of our environment and food chain. Several studies are evaluating how plastics break down into smaller parts, known as microplastics (MPs), and how they impact the health of humans, animals, and ecosystems.&nbsp;</strong></p><p>In this webinar we will present two new methods for microplastic determinations that aim to simplify and expedite this type of analysis. Featuring presentations by two experts in the field, we will see how the use of microwave technology has been applied to microplastic determinations by two different analytical techniques.</p></div></div></div><h5><strong>What you will learn:</strong></h5><ul><li>How microwave solvent extraction can be applied to MPs determinations</li><li>How to combine microwave extraction to Py-GC–MS</li><li>Microwave digestion followed by gravimetric determination of MPs</li><li>The use of the microwave for selective digestion</li></ul><blockquote><p><strong>Presenter:</strong> Prof. Jacopo La Nasa (Department of Chemistry and Industrial Chemistry, University of Pisa )</p><p><strong>Presenter:</strong> Prof. Cezar Augusto Bizzi (Universidade Federal de Santa Maria (UFSM) Departamento de Química (DQ) Setor de Química Industrial e Ambiental (SQIA))</p><p><strong>Presenter:</strong> Gianpaolo Rota (Application Specialist at Milestone)</p></blockquote>

Milestone: Novel methodology for microplastic determination 

Novel methodology for microplastic determination 

Learn how microwave extraction and digestion simplify microplastics analysis, including Py-GC–MS workflows and gravimetric determination of MPs.

Novel methodology for microplastic determination

<h4><strong>Take the first steps to journey from GC/MS ChemStation software into the realm of MassHunter software!</strong></h4><p><strong>MassHunter delivers outstanding performance in all MS processes (GC &amp; LC MS, MSMS, TOF, QTOF, and ICPMS), reducing the number of different software programs required to control and collect analytical data in your laboratory. This software suite provides detailed instrument control, monitoring, and data analysis. Please join us to discover the powerful and time saving tools found in the MassHunter software platforms of qualitative, quantitative, and unknowns data analysis.</strong></p><h5><strong>MassHunter Unknowns Analysis for the Forensic Chemist-Fundamental Workflow Part I</strong></h5><p>The MassHunter Unknowns Analysis video Part I is designed to introduce the student to the workflows involved when using Unknowns Analysis. The video begins a 15-minute PowerPoint explanation of the deconvolution process, difference between deconvolution and peak integration, and some of the variables involved when using this powerful data analysis tool. Working through forensic data, the video is designed to help translate established workflows within ChemStation Data Analysis to MassHunter Unknowns Analysis.</p><blockquote><p><strong>Presenter: </strong>Kirk Lokits, PhD</p><p>Kirk received his B.S. in Forensic Science and Chemistry from Eastern Kentucky University and began working as a Forensic Drug Chemist in the Miami Valley Regional Crime Laboratory in Dayton, Ohio. He then moved to Orlando, Florida where he worked as a Forensic Toxicologist for the Florida Department of Law Enforcement in the Orlando Regional Crime Laboratory and later as a Crime Analyst Supervisor in the Pensacola Regional Crime Laboratory. Kirk left the forensic realm and began his tenure with Hewlett Packard/Agilent Technologies, working as a Customer Service Engineer (CE) supporting the LC, GC, LC/MS, GC/MS, and ICP/MS products. While working for HP Kirk earned his M.S. in Analytical Chemistry from Middle Tennessee State University and in 2005 Kirk left Agilent Technologies to attend the University of Cincinnati to earn his Ph.D. in Analytical Chemistry. After receiving his Ph.D., Kirk worked for the Midwest Research Institute (MRI) in Kansas City, MO where he worked as a Principal Chemist and Sr. Program Manager on Department of Defense projects, staffing, designing, and building remote laboratories for placement throughout the world. In 2014, Kirk re-joined Agilent Technologies as a GC/MS Applications Scientist focusing on forensic applications.</p></blockquote>

Agilent Technologies: GC/MS MassHunter Virtual Workshop

MassHunter Unknowns Analysis for the Forensic Chemist-Fundamental Workflow Part I

Learn basics of MassHunter Unknowns Analysis of this forensic GC/MS series, focusing on deconvolution principles and workflow migration from ChemStation.

MassHunter Unknowns Analysis for the Forensic Chemist

<h4><strong>Take the first steps to journey from GC/MS ChemStation software into the realm of MassHunter software!</strong></h4><p><strong>MassHunter delivers outstanding performance in all MS processes (GC &amp; LC MS, MSMS, TOF, QTOF, and ICPMS), reducing the number of different software programs required to control and collect analytical data in your laboratory. This software suite provides detailed instrument control, monitoring, and data analysis. Please join us to discover the powerful and time saving tools found in the MassHunter software platforms of qualitative, quantitative, and unknowns data analysis.</strong></p><h5><strong>MassHunter Unknowns Analysis for the Forensic Chemist-Fundamental Workflow Part II</strong></h5><p>The MassHunter Unknowns Analysis video Part II is designed to reinforce the workflows of Unknowns Analysis illustrated in Part I to actual forensic samples. The student will also learn how to create additional components, manually and apply background subtraction. Working through forensic data, the video is designed to help translate established workflows within ChemStation Data Analysis to MassHunter Unknowns Analysis.</p><blockquote><p><strong>Presenter: </strong>Kirk Lokits, PhD</p><p>Kirk received his B.S. in Forensic Science and Chemistry from Eastern Kentucky University and began working as a Forensic Drug Chemist in the Miami Valley Regional Crime Laboratory in Dayton, Ohio. He then moved to Orlando, Florida where he worked as a Forensic Toxicologist for the Florida Department of Law Enforcement in the Orlando Regional Crime Laboratory and later as a Crime Analyst Supervisor in the Pensacola Regional Crime Laboratory. Kirk left the forensic realm and began his tenure with Hewlett Packard/Agilent Technologies, working as a Customer Service Engineer (CE) supporting the LC, GC, LC/MS, GC/MS, and ICP/MS products. While working for HP Kirk earned his M.S. in Analytical Chemistry from Middle Tennessee State University and in 2005 Kirk left Agilent Technologies to attend the University of Cincinnati to earn his Ph.D. in Analytical Chemistry. After receiving his Ph.D., Kirk worked for the Midwest Research Institute (MRI) in Kansas City, MO where he worked as a Principal Chemist and Sr. Program Manager on Department of Defense projects, staffing, designing, and building remote laboratories for placement throughout the world. In 2014, Kirk re-joined Agilent Technologies as a GC/MS Applications Scientist focusing on forensic applications.</p></blockquote>

MassHunter Unknowns Analysis for the Forensic Chemist-Fundamental Workflow Part II

MassHunter Unknowns Analysis Part II applies workflows to real forensic samples, focusing on manual component creation and background subtraction.

Related content

Czech scientists develop a material for producing chemicals from water and sunlight, inspired by human enzymes

News from LabRulezGCMS Library - Week 08, 2026

Application of GC×GC for the investigation of fermented beverages (Sarah C. Foster, MDCW 2026)