<p><strong>In this technical tip from </strong><span><strong>Phenomenex</strong></span><strong>, the topic of gas chromatography (GC) column trimming is addressed from a troubleshooting perspective. The key question explored is whether trimming a GC column is necessary and how it impacts chromatographic performance.</strong></p><h3><strong>Why Trim a GC Column?</strong></h3><p>Column trimming is primarily used to <strong>restore chromatographic performance</strong> by removing damaged or contaminated sections, typically located at the column inlet.</p><h5><strong>1. Baseline Bleed, Noise, Ghost Peaks, Poor Peak Shape</strong></h5><ul><li><strong>Cause:</strong> Column contamination</li><li>Removing the contaminated stationary phase at the column entrance helps restore performance.</li></ul><h5><strong>2. Elevated Baseline (Especially at High Temperature)</strong></h5><ul><li><strong>Cause:</strong> Column bleed</li><li>Degradation of the stationary phase due to <strong>oxygen exposure or thermal damage</strong> leads to increased baseline.</li></ul><h5><strong>3. Ghost Peaks (Peaks Without Injection)</strong></h5><ul><li><strong>Cause:</strong> Residual sample or contamination</li><li>Compounds trapped at the beginning of the column can appear as peaks even when no sample is injected.</li></ul><h5><strong>4. Peak Tailing (Asymmetrical Peaks)</strong></h5><ul><li><strong>Cause:</strong> Damaged or contaminated column sections</li><li>These issues result in <strong>adsorption effects or poor flow dynamics</strong>.</li></ul><h5><strong>5. Retention Time Shifts</strong></h5><ul><li><strong>Cause:</strong> Contamination or damage near the inlet</li><li>Although trimming slightly changes retention time, it can correct shifts caused by inlet-side issues.</li></ul><h5><strong>6. Baseline Noise and Spikes</strong></h5><ul><li><strong>Cause:</strong> Particulate matter or degraded stationary phase</li><li>These can lead to <strong>detector instability</strong> and random signal fluctuations.</li></ul><h5><strong>7. Baseline Drift or Wander</strong></h5><ul><li><strong>Cause:</strong> Contamination or oxidized column sections</li><li>Removing these regions stabilizes the baseline.</li></ul><h5><strong>8. Loss of Resolution or Sensitivity</strong></h5><ul><li><strong>Cause:</strong> General column degradation</li><li>Trimming removes the most exposed and damaged portions, effectively <strong>rejuvenating column performance</strong>.</li></ul><h3><strong>How to Trim a GC Column</strong></h3><p>A capillary GC column consists of:</p><ul><li><strong>Polyimide outer coating</strong> (protective layer)</li><li><strong>Fused silica tubing</strong> (fragile but flexible core)</li></ul><h3><strong>Step-by-Step Procedure</strong></h3><h5><strong>1. Scoring the Column</strong></h5><ul><li>Use a <strong>ceramic wafer</strong></li><li>Hold it at an <strong>inclined angle</strong></li><li>Score the polyimide coating <strong>perpendicular to the column</strong></li></ul><h5><strong>2. Breaking the Column</strong></h5><ul><li>Perform a <strong>quick, decisive flick</strong></li><li>This ensures a <strong>clean, square cut</strong></li></ul><h5><strong>3. Inspecting the Cut</strong></h5><p>After trimming, visually inspect the column end.</p><h3><strong>Examples of Column Cuts</strong></h3><h4><strong>Good Cut</strong></h4><ul><li>Clean, <strong>square end</strong></li><li>Ensures proper sealing and connection</li></ul><h5><strong>Bad Cuts</strong></h5><ul><li><strong>Slight Irregularity</strong><ul><li>Small imperfection at the edge</li><li>Can cause <strong>leaks</strong> and <strong>active sites</strong></li></ul></li><li><strong>Poor / Rough Cuts</strong><ul><li>Uneven or jagged edges</li><li>Lead to:<ul><li>Poor connections</li><li>Active sites</li><li>Peak tailing</li></ul></li></ul></li></ul><h2><strong>Conclusion</strong></h2><p>Trimming a GC column is a simple yet effective troubleshooting step. By removing contaminated or damaged sections—especially near the inlet—it can resolve a wide range of chromatographic issues, including baseline instability, ghost peaks, and loss of performance.</p><p>Proper cutting technique is essential to avoid introducing new problems such as leaks or active sites.</p>

Trimming a GC Column: Purpose, Symptoms, and Proper Technique

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 30th March 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by <strong>Agilent Technologies, Thermo Fisher Scientific, </strong>brochure by<strong> Shimadzu </strong>and presentation by<strong> MDCW / LECO!</strong></p><h3><strong>1. Agilent Technologies: Extraction and Analysis of Pesticides from Water by Solid Phase Extraction and GC/MS</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_extraction_analysis_pesticides_water_gcms_5994_8996en_agilent_28fc35d0e7.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Drinking water is defined as water intended for human consumption obtained from different sources. Several guidelines/regulations exist for ensuring that undesirable substances such as pesticides are not present in excessive amounts that may be harmful to human health. These regulations ensure that water intended for human consumption can be consumed safely. In India, the Bureau of Indian Standards (BIS) has set regulatory limits for residual pesticides in drinking water (IS 10500)<sup>1</sup> , packaged drinking water (IS 14543)<sup>2</sup> , and natural mineral water (IS 13428).<sup>3</sup> A total of 26 pesticides are regulated by BIS standards, of which four compounds (monocrotophos, phorate, 2,4-D, and isoproturon) are more suitable for analysis by liquid chromatography.&nbsp;</p><p>EPA Method 525.2 is a general-purpose method for determination of organic compounds in finished drinking water or water from any source or treatment stage.<sup>4</sup> This method is applicable to a range of organic compounds that are partitioned from the water sample onto a C18 organic phase packed in a disk or cartridge. The organic compounds are then eluted using a suitable eluent, concentrated, and analyzed by GC/MS.&nbsp;</p><p>This application note describes the use of EPA Method 525.2 for extraction of pesticide residues at trace levels in water using solid-phase extraction (Agilent Bond Elut C18: Straight barrel cartridges, p/n 12102118) and analysis using Agilent 8890-5977 GC/MS.&nbsp;</p><p>Excellent linearity with R2 &gt; 0.995 was obtained for all pesticides considered for the study. Recoveries were obtained in the range of 80–120% with associated RSDs &lt; 15% at 0.005–0.080 ng/mL level of fortification.</p><h4><strong>Experimental</strong></h4><h5><strong>Instrument parameters</strong></h5><ul><li><strong>GC:</strong> <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=8890"><strong>Agilent 8890</strong></a></li><li><strong>Column:</strong> Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=J%26W+HP-5ms"><strong>J&amp;W HP-5ms</strong></a> UI 30 m × 0.25 mm, 0.25 μm&nbsp;</li><li><strong>Carrier Gas:</strong> Helium, constant flow, 1.2 mL/min&nbsp;</li><li><strong>Inlet:</strong> Agilent Multimode Inlet (MMI)</li><li><strong>MS:</strong> <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=1&amp;search=5977"><strong>5977 GC/MS</strong></a></li></ul><h4><strong>Conclusion&nbsp;</strong></h4><p>A simple, easy, and efficient method based on EPA 525.2 was implemented for the determination of 22 pesticides in water. The method demonstrated good sensitivity, precision, and accuracy, and allows for rapid analysis. The results demonstrate that pesticide residues can be detected below the current maximum residue levels (MRL) required by the BIS specifications. Acceptable recoveries and precision were obtained at concentrations as low as 5 ng/L for all pesticides. The method is ideally suited for use in a regulatory laboratory for the determination of pesticides in surface, drinking, and packaged drinking water.</p><h3><strong>2. MDCW / LECO: Exploring PFAS in Consumer Goods Using GCxGC and High-Resolution Mass Spectrometry</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_3_Alonso_6f61e3ea43.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Per- and polyfluoroalkyl substances (PFAS) are widely used in consumer and industrial products due to their unique physicochemical properties, but their persistence and potential health risks have made their detection increasingly important. This study focuses on developing an untargeted analytical approach for screening PFAS and related compounds in consumer goods using advanced chromatographic and mass spectrometric techniques.</p><p>The analytical workflow combines gas chromatography with time-of-flight mass spectrometry (GC-TOFMS) and comprehensive two-dimensional gas chromatography coupled with high-resolution TOFMS (GC×GC-HRTOFMS), using systems such as the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1097"><strong>LECO Pegasus® BTX</strong> </a>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/38"><strong>Pegasus® HRT+</strong></a> platforms. Sample introduction is performed via thermal desorption or pyrolysis, enabling analysis of both volatile and complex matrices. High-resolution MS provides accurate mass measurements and elemental composition, which are essential for identifying unknown compounds and reducing matrix interferences.</p><p>In the first case study, anti-fog solutions were analyzed and found to contain a wide range of compounds, including fluorotelomer alcohols and related PFAS species. While GC-TOFMS enabled initial screening, high-resolution TOFMS was necessary to characterize unknown compounds through accurate mass determination and complementary ionization techniques (EI and PCI). This approach allowed tentative structural assignment using external databases, demonstrating the importance of HRMS in identifying compounds not present in standard libraries.</p><p>The second case study focused on chewing gum, a highly complex matrix with diverse chemical constituents and trace-level analytes. The use of GC×GC-HRTOFMS significantly improved chromatographic separation and spectral clarity, enabling detailed profiling of volatile and semi-volatile compounds. A dedicated PFAS screening workflow based on mass defect analysis and spectral filtering was applied, leveraging the characteristic CF₂ patterns of PFAS molecules to simplify data interpretation.</p><p>Despite the complexity of the sample, no PFAS were detected in the chewing gum, its packaging, or the box. Overall, the study demonstrates that combining GC×GC separation, high-resolution mass spectrometry, and advanced data processing tools provides a powerful and reliable strategy for untargeted PFAS screening in complex consumer products, particularly when unknown or emerging contaminants are of concern.</p><h3><strong>3. Shimadzu: Gas Chromatograph Nexis GC-2060</strong></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c184_e056_06c3456516.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The Shimadzu <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=3&amp;search=Nexis+GC-2060"><strong>Nexis GC-2060</strong></a> represents a new generation of gas chromatographs, built on over 70 years of GC development and designed to serve as a flexible and future-proof analytical platform. It integrates the concept of <i>Analytical Intelligence</i>, which enables automated system monitoring, troubleshooting, and optimization, helping both experienced and less experienced users achieve reliable and consistent results. The system is highly configurable, supporting up to two injectors, three injection units, and four detectors simultaneously, allowing a single instrument to cover multiple analytical applications.</p><p>A key advantage of the Nexis GC-2060 is its versatility in sample introduction and detection. The Multi-Mode Injection Unit (MMI) supports a wide range of injection techniques, including split/splitless, PTV, direct injection, large-volume injection (LVI), and thermal desorption, significantly reducing the need for complex sample preparation. The system is also equipped with next-generation detectors such as FID and TCD, offering high sensitivity, stability, and linearity, with additional detector options (ECD, FPD, FTD, BID) enabling broad application coverage.</p><p>The instrument is designed to maximize laboratory efficiency and minimize downtime. Features such as tool-free column installation (ClickTek), automated startup/shutdown, Easy sTop maintenance mode, and Clean Pilot for automated column conditioning simplify routine operation and reduce manual intervention. In addition, Eco Idling technology automatically optimizes gas and power consumption during standby, significantly lowering operational costs while maintaining readiness for analysis.</p><p>From an analytical performance perspective, the Nexis GC-2060 delivers excellent reproducibility and sensitivity, supported by advanced autosamplers (e.g., AOC-30) and compatibility with third-party systems. The platform supports hydrogen carrier gas for faster analysis and includes smart gas management features such as automatic gas switching. Its modular design allows seamless integration with various sample preparation systems, autosamplers, and detectors, ensuring adaptability to evolving laboratory needs.</p><p>Overall, the Nexis GC-2060 combines high performance, operational efficiency, and flexibility in a single platform, making it suitable for a wide range of applications, including pharmaceutical analysis, environmental testing, food analysis, and energy-related measurements. Its scalability and continuous software updates ensure long-term usability and alignment with future analytical requirements.</p><h3><strong>4. Thermo Fisher Scientific: Accurate multi-component blast furnace gas analysis maximizes iron production and minimizes coke consumption</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/epm_AN_Iron_Production_Prima_PRO_bd5de98b44.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Over a billion tonnes of iron a year are produced in blast furnaces, representing around 94% of global iron production¹. The blast furnace consists of a large steel stack, lined with refractory brick. Iron ore, coke and limestone are dropped into the top of the furnace and preheated air blown into the bottom through nozzles called ‘Tuyeres’. Iron oxides are reduced in the melting zone, or ‘Bosh’, forming liquid iron (called ‘hot metal’) and liquid slag. These liquid products are drained from the furnace at regular intervals, and the blast furnace will run continuously for several years, until the refractory lining needs replacing.</p><p>Analysis of carbon monoxide (CO) and carbon dioxide (CO₂) give vital information on the efficiency of the reduction processes. Historically, two non-dispersive infrared (NDIR) analyzers were used, one to measure CO, the other CO₂. Additional discrete analyzers were required to monitor oxygen and hydrogen – typically paramagnetic O₂ analyzers and thermal conductivity analyzers for H₂.&nbsp;</p><p>Thermo Scientific™ process mass spectrometers have been widely used for many years for key gas analysis applications in iron and steel plants, including blast furnace, basic oxygen steelmaking, coke oven gas analysis, secondary steel process control, fuel gas analysis and direct reduction iron processes²</p><h4><strong>Process control requirements&nbsp;</strong></h4><p>The advantages of process MS over conventional analysis techniques have been proven over many years in the iron and steel industry. The ability to measure a wide range of components on a single analyzer, coupled with advanced calibration, data transmission, and self-diagnostic software, makes the modern mass spectrometer ideal for integration into the modern plant. On blast furnaces, superior gas analysis is being used to calculate gas efficiency, mass and heat balances, and heat profiles through probe analysis, as well as being an essential tool in the early detection of cooling water leaks and sample system failures.&nbsp;</p><p>Figure 2 shows 64 hours of data from a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2305"><strong>Thermo Scientific™ Prima™ PRO Process MS</strong></a> monitoring the six gases in a blast furnace top gas every 10 seconds. The pulse every 12 hours is generated by an automatic nitrogen blowback from the sample conditioning system, to keep the sample probe clear of particulates.</p><h4><strong>Hydrogen analysis&nbsp;</strong></h4><p>An increase in the hydrogen level in the furnace can indicate a leak from the furnace cooling system, as water dissociates into hydrogen and oxygen in the furnace. This has implications both for plant efficiency and plant safety. Water leaks will lower the furnace temperature, causing heat loss and a consequent increase in fuel consumption. In extreme cases, damage to plant and personnel can be caused by ignition of these hazardous mixtures of explosive gases.&nbsp;</p><p>Figure 4 shows a plot of top gas hydrogen concentration measured by Thermo Scientific process MS over a 24-hour period, with the departure of the measured H2 value from that predicted by the mass balance model indicating a water leak. This leak was caused by the failure of a cooling member, and the furnace was taken off blast for repair. The mass spectrometer’s ability to provide fast, accurate hydrogen analysis removes the need for an additional discrete analyzer.&nbsp;</p><p>Gas composition measurement is particularly important during the end-of-campaign blowdown that takes place prior to rebuilds and relines, because explosive gas mixtures can be generated.&nbsp;</p><h4><strong>Probe analysis&nbsp;</strong></h4><p>The fast analysis provided by MS offers another significant advantage over discrete analyzers—a number of process streams can be analyzed using a single instrument. This is achieved using a fully automated multi-inlet system, designed to switch between sample streams at high speeds with minimal sample flushing times. For example, as well as furnace top gas, the MS can also analyze gases from probes placed above and below the burden (the furnace charge of iron ore, coke and limestone). These are known as above-burden and sub-burden probes and provide valuable information on fuel efficiency, iron conversion and furnace charging. Figure 5 shows a schematic of these two probes; they can be moved across the furnace to build a cross-sectional profile of the furnace.</p><h4><strong>Summary&nbsp;</strong></h4><p>Thermo Scientific process mass spectrometers have been successfully monitoring blast furnace off gas at many of the world’s iron and steel companies for over 30 years. For a blast furnace producing 5,000 tonnes a day, a reduction in coke consumption of just 10 kg per tonne of iron produced provides a payback of over $10,000 a day. Users report that the combination of fast, accurate MS gas analysis for gas efficiency, heat and mass balances and hydrogen analysis, with advanced process control and mathematical modeling, has reduced coke consumption by up to 100 kg per tonne and increased iron production. Upgrading to Prima PRO MS can therefore result in complete installation payback within a few weeks.&nbsp;</p><ul><li>Reduces coke consumption&nbsp;</li><li>Produces consistent quality iron&nbsp;</li><li>Reduces downstream processing costs&nbsp;</li><li>Detects water leaks fast&nbsp;</li><li>Improves thermal control of furnace&nbsp;</li><li>Enables safer operation during blowdown</li></ul>

News from LabRulezGCMS Library - Week 14, 2026

<h3><strong>We're excited to announce that </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a><strong> version 10.1.2 is now available!</strong></h3><p><strong>This minor update expands Clarity’s portfolio with new control modules.</strong></p><h4><strong>Newly added Instrument control modules</strong></h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4><strong>Updated Instrument control modules</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168"><strong>Ecom</strong></a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328"><strong>Knauer</strong></a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote><p>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1"><strong>Changelog</strong></a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622"><strong>Clarity 10.1 release highlights</strong></a>.</p><p>Clarity can control <strong>1000+ instruments</strong>; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls"><strong>list can be previewed here</strong></a>.</p></blockquote><h4><strong>Supported Instruments in Clarity (DataApex) — Quick Guide</strong></h4><p>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via <strong>digital control (DD)</strong> and <strong>analog acquisition (A/D)</strong> using the <strong>Colibrick</strong> module.</p><h5><strong>Gas Chromatographs (GC)</strong></h5><p>Digital integration over LAN/RS232 (many via ICF):</p><ul><li><strong>Agilent</strong>: 5890, 6890, 7890, 8860, 8890, <strong>Intuvo 9000</strong></li><li><strong>Shimadzu</strong>: GC-2010/2014, <strong>Nexis GC-2030</strong></li><li><strong>Thermo Fisher</strong>: TRACE 1300/1310</li><li><strong>PerkinElmer</strong>: Clarus 400–690</li><li>Also supported: <strong>Dani</strong>, <strong>Ellutia</strong>, <strong>Young In Chromass</strong>, <strong>Apix</strong>, <strong>Fuli</strong>, <strong>GOW-MAC</strong> (selected models)</li></ul><blockquote><p>Note: Most Agilent 6890–8890 and Intuvo use <strong>LAN – ICF</strong>.</p></blockquote><h5><strong>HPLC Systems</strong></h5><p>Full system/module control:</p><ul><li><strong>Agilent</strong> 1100–<strong>1290 Infinity II</strong> (ICF)</li><li><strong>Shimadzu</strong> LC-10/20 and <strong>Nexera LC-40</strong></li><li><strong>PerkinElmer</strong> Flexar / NexSAR</li><li><strong>Knauer</strong> Azura / BlueShadow / Smartline</li><li><strong>Hitachi</strong> Chromaster / Primaide</li><li><strong>Young In Chromass</strong> ChroZen series</li><li><strong>Sykam</strong> S500–S600, <strong>Watrex</strong> Streamline, <strong>Hanon</strong> LC7000–7300</li></ul><h5><strong>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</strong></h5><ul><li><strong>Pumps</strong>: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li><strong>Detectors</strong>: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li><strong>Column Ovens</strong>: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li><strong>Fraction Collectors</strong>: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5><strong>Autosamplers</strong></h5><ul><li><strong>Agilent</strong> GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li><strong>Shimadzu</strong> AOC-20 / AOC-5000+, SIL-10 / SIL-20 / <strong>SIL-40</strong> series</li><li><strong>CTC Analytics PAL</strong>, <strong>HTA</strong> autosamplers, <strong>Spark</strong> Alias/UHPLC, <strong>Knauer</strong> AS 6.1L</li><li><strong>PerkinElmer</strong> Flexar / NexSAR AS</li></ul><h5><strong>Other Devices</strong></h5><ul><li><strong>GC×GC modulators</strong> (e.g., Charles University GC×GC Modulator)</li><li><strong>Valves &amp; switch modules</strong> (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li><strong>Degassers, flow monitors, managers, interfaces</strong></li><li><strong>LC-MS / GC-MS</strong>: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li><strong>Balances (EA extension)</strong>: Mettler Toledo, Sartorius</li></ul><h5><strong>Analog Acquisition (Colibrick)</strong></h5><p>A/D support for legacy or analog-output devices:</p><ul><li><strong>GC</strong>: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li><strong>HPLC Detectors</strong>: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li><strong>Elemental &amp; Amino Acid Analyzers</strong>: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul><p>If you are interested in a <strong>DEMO VERSION</strong>, contact us!</p>

DataApex Clarity Chromatography software 10.1.2 just released!

Article

Product

Application

Academy

Presentation

Software

Video

Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

DataApex

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

Phenomenex

Separation Science

The Analytical Scientist

Agilent Technologies

Technology Networks

LECO

<ul>
<li><p><strong>Discuss what GC-MS/MS is and what applicaitons it is used for (Dioxins, POPs, etc.)</strong></p>
</li>
<li><p><strong>Transition into an overview of APGC as a solution</strong></p>
</li>
<li><p><strong>Discuss challenges or limitations of the current GC/MS/MS technology</strong></p>
</li>
<li><p><strong>Share why using nitrogen as a carrier gas for GC/MS/MS analysis is optimal</strong></p>
</li>
</ul>
<p>Webinar Learning Objectives:</p>
<ul>
<li><p>Understanding GC-MS/MS and Its Applications:- Discuss the principles of gas chromatography-mass spectrometry (GC-MS/MS) and its role in analytical chemistry.- Explore specific applications of GC-MS/MS, including its use in detecting dioxins, persistent organic pollutants (POPs), and other environmental contaminants.</p>
</li>
<li><p>Introduction to APGC (Atmospheric Pressure Gas Chromatography):-. Provide an overview of Atmospheric Pressure Gas Chromatography (APGC) as an alternative solution to traditional GC-MS/MS.- Highlight the advantages and unique features of APGC, such as improved sensitivity, reduced matrix effects, and enhanced selectivity.</p>
</li>
<li><p>Challenges and Innovations in GC-MS/MS Technology:- Identify the current challenges and limitations faced by GC-MS/MS technology.- Discuss recent innovations and advancements aimed at overcoming these challenges.- Emphasize the importance of using nitrogen as a carrier gas for GC-MS/MS analysis, considering its inertness, availability, and compatibility with various detectors.</p>
</li>
</ul>
<blockquote>
<p><strong>Prtesenter:</strong> Frank Dorman (Senior Principal Market Development Mgr, Waters Corporation)</p>
</blockquote>
<blockquote>
<p>Frank Dorman is currently Senior Principal Market Development Manager for Waters focusing on their global environmental business and, concurrently, a Resident Scholar in the Chemistry Department at Dartmouth College in Hanover, NH where he is active in teaching analytical chemistry to undergraduates and graduate students.</p>
</blockquote>
<blockquote>
<p>In his role at Waters, Frank manages the research-focused environmental market, external collaborations, and interfaces with R&amp;D for new product development. Prior to this, Frank was an Associate Professor in the Department of Biochemistry and Molecular Biology (BMB) sat Penn State University in University Park, PA. At Penn State, Frank served as a member of the Graduate Faculty in: Biochemistry, Microbiology and Molecular Biology (BMMB), Chemistry (CHEM), Biogeochemistry (BGC) and the Forensic Science Program (FRNSC) and the Center for Molecular Toxicology and Carcinogenesis. Franks scientific interests are in gas and liquid chromatography and fundamental characterization, instrumentation and column development, as well as mass spectrometry and atomic spectroscopy as applied to trace analysis in complex sample matrices.</p>
</blockquote>
<blockquote>
<p><strong>Presenter:</strong> Sarah Dowd (Principal Mass Spectrometry Applications Specialist, Waters Corporation)</p>
</blockquote>
<blockquote>
<p>Sarah Dowd joined Waters as a mass spectrometry application specialist in 2015 after earning her PhD in analytical chemistry from the University of Illinois at Urbana Champaign.</p>
</blockquote>
<blockquote>
<p>In her eight years at Waters in the Americas application lab, Sarah has collaborated with many customers looking to expand the MS capabilities of their laboratories with Water&#39;s instruments and software. Specializing in analyses in food, environmental, and polymeric materials characterization, she has done extensive work looking at environmental contaminants with tandem quadrupole and high resolution mass spectrometers.</p>
</blockquote>
<blockquote>
<p>One of the hot topics for the past couple of years is the analysis of per- and polyfluoroalkyl substances (PFAS) and Sarah has collaborated with customers and other scientists within Waters to guide the next phase of PFAS testing with Waters mass spectrometry systems.</p>
</blockquote>


Waters Corporation: APGC Roundtable: Unveiling the Pathways of GC-MS/MS Evolution

APGC Roundtable: Unveiling the Pathways of GC-MS/MS Evolution

Discuss what GC-MS/MS is and what applicaitons it is used for (Dioxins, POPs, etc.)

APGC Roundtable: Unveiling the Pathways of GC-MS/MS Evo

<p><strong>Join us for an exclusive one-day hybrid event, here we&#39;ll explore the latest trends and innovations in microplastics analysis. The morning session will be live-streamed and recorded, allowing virtual  articipation for those unable to attend in person.</strong></p>
<p>We are excited to invite you to a special <strong>hybrid event</strong> in partnership with <strong>i3 Membrane</strong>, where we will delve into the latest trends and innovations in microplastics analysis. Whether you join us in person or virtually, you’ll gain invaluable insights and hands-on experience.</p>
<p><strong>Event also available in live stream</strong></p>
<h3><strong>Agenda:</strong></h3>
<ul>
<li><p><strong>Morning session:</strong> Gain key insights into <a href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=microplastics+analysis"><strong>microplastics analysis</strong></a>, as well as <a href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=PFAS"><strong>PFAS</strong></a> and other environmental contaminants, through engaging presentations by top researchers and industry experts.</p>
</li>
<li><p><strong>Afternoon session:</strong> Participate in interactive workshops designed to enhance your practical skills in sample preparation. This provides a unique opportunity to master advanced techniques and methodologies under the guidance of professionals. Attend a live demo on the IR QCL-based <a href="https://icpms.labrulez.com/library?mainauthorItems=10&amp;search=8700+LDIR"><strong>8700 LDIR</strong></a>. Additionally, enjoy a guided laboratory tour offering an exclusive glimpse into the state-of-the-art facilities at the HEREON campus.</p>
</li>
</ul>
<h5>9:15 a.m. - Welcome</h5>
<h5>9:20 a.m. - <strong>From Macroplastics to Mesoplastics: Challenges and Solutions</strong></h5>
<ul>
<li>Dr. Marion Börger, Agilent Technologies,</li>
<li>Dr. Andreas Kerstan, Agilent Technologies</li>
</ul>
<h5>9:40 a.m. - <strong>i3 Membrane Session: Filter Membranes/Packaging - Jacobs</strong></h5>
<ul>
<li>Kathrin Hahn, i3 Membrane</li>
</ul>
<h5>10:00 a.m. - <strong>Exploring Microplastic Sources and Distribution in Australian Soils</strong></h5>
<ul>
<li>Subharthe Samandra, University of Melbourne</li>
</ul>
<h5>10:20 a.m. - <strong>Advancing Analysis: Eurofins&#39; Path to ISO 17025 Accreditation for Microplastics Testing</strong></h5>
<ul>
<li>Julia Jäger, Eurofins</li>
</ul>
<h5>10:40 a.m. - Coffee Break</h5>
<h5>11:00 a.m. - <strong>Validation and Application of LDIR Imaging to Analyze Microplastics in Marine Samples</strong></h5>
<ul>
<li>Lars Hildebrandt, Hereon</li>
</ul>
<h5>11:20 a.m. - <strong>Applying Multiple Analytical Techniques to Answer Open Questions About Offshore Wind</strong></h5>
<ul>
<li>Alexa Zonderman, Hereon</li>
</ul>
<h5>11:40 a.m. - <strong>Sample-Based Subsampling Strategies to Analyze Large Quantities of Particles in LDIR</strong></h5>
<ul>
<li>Manuel Andrade, University La Coruna</li>
</ul>
<h5>12:00 p.m. - <strong>Beyond the Surface: Spotlight on Plastic [Metal(loid)] Additive Leaching and Unseen Contaminants</strong></h5>
<ul>
<li>Ole Klein, Hereon</li>
</ul>
<h5>12:20 p.m. - <strong>Microplastics back in food- Advantages of Thermal Desorption for a wide range of Samples</strong></h5>
<h5>12:40 p.m. - <strong>Struggling with Solvent Effects During the Analysis of PFAS</strong></h5>
<ul>
<li>Dr. Axel Ritter, Agilent Technologies</li>
</ul>
<h5>1:00 p.m. - Lunch Break</h5>
<h5>2:00 p.m. - <strong>An Analytical Toolbox to Unravel PFAS Source Fingerprints</strong></h5>
<ul>
<li>Frank Menger, Hereon</li>
</ul>
<h5>2:20 p.m. - <strong>LDIR for Assessment of Microplastics in the VAMAS Ring Trial and Tissue in a Murine Infection Model</strong></h5>
<ul>
<li>Christoph Krafft, IPHT</li>
</ul>
<h5>2:40 p.m. - <strong>Label-Free Infrared Spectroscopic Micro- and Nanoplastics Detection in Complex Matrices</strong></h5>
<ul>
<li>Markus Brandstetter, Recendt</li>
</ul>
<h5>3:00 p.m. - <strong>Break in Dividing the Guests into Subgroups</strong></h5>
<h5>3:10 p.m. - <strong>Lab Visits: Organic Lab, Microplastics Lab, Sample Prep, LDIR, and Other Techniques</strong></h5>
<h5>4:50 p.m. - Wrap up</h5>
<h3><strong>Meeting Information</strong></h3>
<ul>
<li><p><strong>Date:</strong> 29 October 2024</p>
</li>
<li><p><strong>Time:</strong> 9:00 a.m. to 4:50 p.m. CEST</p>
</li>
<li><p><strong>Location:</strong> GITZ GmbH, Max-Planck-Straße 2, 21502 Geesthacht, Germany </p>
</li>
<li><p><strong>Meals included:</strong> Enjoy complimentary lunch and snacks during the event.</p>
</li>
</ul>
<p><strong>Limited spots available!</strong> Hurry, to secure yours today.</p>
<blockquote>
<p><a href="https://explore.agilent.com/microplameeting24#form"><strong>Secure your spot</strong></a></p>
</blockquote>


Agilent Microplastics Meeting 2024

We'll explore the latest trends and innovations in microplastics analysis.

<p><strong>We’ll explore how outlier setup can help you focus on samples and compounds that require your attention, ensuring accurate and reliable results.</strong></p><p>Additionally, you’ll learn how viewing compounds and calibration at a glance can expedite data review, making the process faster and more intuitive.</p><p>Finally, we’ll demonstrate how easily you can summarize your results in comprehensive reports or export them to Excel, streamlining your workflow and enhancing productivity.</p><p>Don’t miss this opportunity to enhance your data analysis skills with MassHunter Quant!</p><blockquote><p><strong>Presenter:</strong> Peter Kornas (LC/MS Applikationsspezialist, Agilent Technologies)</p><p>Peter Kornas has more than 10 years of experience in the development and validation of analytical methods for the determination of pesticides, mycotoxins and contaminants using LC/MS/MS. Before joining Agilent as an LC/MS application specialist in 2018, he worked as an analytical chemist in the food industry. During this time, he was responsible for the development and validation of analytical methods and worked in close coordination with Regulatory Affairs to ensure compliance with the legal requirements of the LC/MS method portfolio.</p></blockquote>

Agilent Technologies: MassHunter Masterclass Months

MassHunter Quant – A Fast and Easy Way from Data to Results

Join us and discover how quickly a quantitation method can be set up, enabling efficient data processing.

<p><strong>Join us for an insightful webinar where we will explore the critical aspects of differentiating good from bad data and how this distinction can significantly influence your results. From screening to quantification, discover the value of targeted data analysis workflows using non-targeted data with our innovative software and hardware.</strong></p><p>Find by Formula algorithm. Learn to identify the most suitable MS/MS approach for your experiments, initiate quantitation for your compounds of interest, and incorporate retention times (RTs) and MS/MS spectra into a custom database and library.</p><p>This session is designed to enhance your understanding and application of Q-TOF data analysis, ensuring robust and reliable outcomes.</p><blockquote><p><strong>Presenter:</strong> Hannah Florance (Agilent Technologies)</p><p>Hannah has had multiple roles in the life sciences, starting as a protein chemist, before moving into proteomics and then metabolomics. A major part of her time working in academia involved running LC and GCMS core facilities supporting projects ranging from synthetic biology to cancer research. She is currently an LCMS applications specialist for Agilent.<br><br><strong>Presenter:</strong> Stefan Schaebler (Application Specialist LC/MS, Agilent Technologies)</p><p>Stefan completed his PhD in Biology, specializing in LC-MS-based lipidomics and metabolomics. Following his doctoral studies, he joined Agilent Technologies as an LC/MS Application Specialist. In this role, Stefan focuses on small molecule applications using LC-QTOF, with a strong emphasis on software tools and data interpretation.</p></blockquote>

MassHunter Qual – The Solid Pillar in Q-TOF Data Analysis

We will explore the critical aspects of differentiating good from bad data and how this distinction can significantly influence your results.

<div><p><strong>In this session, discover how Wiley’s KnowItAll saves hours of GC-MS manual analysis time by combining fast, flexible deconvolution with an integrated reference database search into a single, automated workflow to identify components.</strong></p><p><strong>We will demonstrate through a series of live examples:</strong></p><ul><li>KnowItAll’s various methods for GC-MS analysis and how they can impact your workflow.</li><li>Professors and students engaged in chemistry and mass spectrometry courses or lab work.</li></ul><p><strong>About KnowItAll: </strong>KnowItAll combines all the tools and spectral databases you need for effective analysis into a single, easy-to-use interface to make your lab its most efficient. Compatible with over 130 instrument formats, it streamlines your entire workflow regardless of how many techniques and instruments you use. Learn more at sciencesolutions.wiley.com</p><blockquote><p><strong>Presenter:</strong> Dr. Leanna Ergin (Associate Editor, Wiley Science Solutions)</p><p>Dr. Leanna Ergin is an Associate Editor for Wiley Science Solutions, for which she helps create tools for spectroscopy, structural, and scientific standard reference data and helps create innovative software applications. Leanna completed her PhD in Clinical-Bioanalytical Chemistry from Cleveland State University, where she developed a protocol for processing hyperspectral image data that distinguishes the spectra, removes degeneracies caused by symmetry, and is generalized to work with any number of wavelength dimensions and spectra. The results are mapped to the full RGB colorspace of modern computer displays. Leanna joined Wiley in 2022.</p><div><strong>Presenter:</strong> Dr. Michelle D’Souza (Product Manager, Software Products, Wiley Science Solutions)</div><p>Dr. D’Souza has over 15 years of experience in the management and development of spectroscopy software, including her current position as product manager for software products at Wiley Science Solutions and prior to that at Bio-Rad Laboratories, Inc. She also worked many years in the pharmaceutical industry after obtaining a Ph.D. in chemistry from Northern Illinois University.</p></blockquote></div>

The Analytical Scientist: Introduction to KnowItAll for Mass Spectrometry

Introduction to KnowItAll for Mass Spectrometry

Discover how Wiley’s KnowItAll saves hours of GC-MS manual analysis time by combining fast, flexible deconvolution with an integrated reference database

<div><div id="inner_content_body_text" data-content-id="391110"><p><strong>Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals prevalent across numerous industries and used in many everyday products, but their persistent and bioaccumulative nature raises critical health and environmental concerns. Join us for our upcoming Ask Me Anything (AMA) Q&amp;A session, where you can explore the latest research, regulatory challenges and advancements in the field.</strong></p><p>During this hour-long virtual session, you’ll have the unique opportunity to ask your most pressing questions directly to our expert speaker, Dr. Ian Ross, in real time.</p><h4><strong>About Our Expert</strong></h4><p>We are honored to host Dr. Ian Ross, Global PFAS Practice Lead at CDM Smith and visiting professor at Manchester Metropolitan University. Dr. Ross is a distinguished biochemist specializing in contaminated land assessment and PFAS decontamination. His extensive expertise is reflected in over 100 publications, including a comprehensive 204-page chapter on PFAS in the Emerging Contaminants Handbook.</p><h4><strong>What to Expect</strong></h4><p>Ian will connect with our live audience to address a broad spectrum of topics related to PFAS. While the spontaneous nature of an AMA session makes it impossible to predict every question, we anticipate discussions will focus on:</p><ul><li><strong>PFAS contamination:</strong> Latest research and case studies</li><li><strong>Environmental and health impacts:</strong> Emerging evidence and implications</li><li><strong>Regulatory challenges: </strong>Current frameworks and future directions</li><li><strong>Applications and concerns:</strong> Industrial uses and associated risks</li></ul><div><div><h4><strong>Why Attend?</strong></h4></div></div><ul><li><strong>Expert insights:</strong> Gain knowledge directly from a leading authority in PFAS.</li><li><strong>Live interaction:</strong> Have your questions addressed in real time for personalized answers.</li><li><strong>Exclusive content:</strong> Access in-depth discussions that you won't find anywhere else.</li></ul><p><strong>Space is limited! Register now to secure your spot for this exclusive AMA session.</strong></p><p><span><strong>Presenter:</strong> Ian Ross, PhD </span>(CDM Smith / Global PFAS Practice Lead, Manchester Metropolitan University)</p></div></div>

Technology Networks: Ask Me Anything: PFAS

Ask Me Anything: PFAS

Ian will connect with our live audience to address a broad spectrum of topics related to PFAS.

<p><strong>Sample preparation plays a significant role in GC–MS analysis, with various approaches available to enhance analytical sensitivity and provide a more comprehensive sample profile. Understanding the science behind microextraction techniques, such as SPME and sorptive extraction, enables chemists to optimize methods for challenging matrices, thus uncovering more from your sample.</strong></p><p>In this webinar, Professor Elia Psillakis from the Technical University of Crete will explore advanced sample preparation techniques for GC–MS. She will focus on evolving microextraction methods, including SPME, thin-film SPME, SPME Arrow, vacuum-assisted SPME, and HiSorb. Professor Psillakis will discuss the fundamentals of these extraction techniques and explain how a deeper understanding of the sample preparation workflow can lead to improved qualitative and quantitative GC–MS analysis, resulting in more accurate and efficient extractions.</p><p><strong>By attending this presentation, you will:</strong></p><ul><li>Understand the core scientific principles behind micro-extraction methods for GC–MS, including SPME and high-capacity extraction techniques</li><li>See how SPME is used in various applications, and how advanced sample concentration techniques can extend the scope of your analysis</li><li>Explore how vacuum-assisted extraction technologies improve sensitivity and efficiency in the analysis of complex samples</li></ul><blockquote><p><strong>Presenter:</strong> Elia Psillakis (Professor, Aquatic Chemistry Laboratory, Technical University of Crete)</p><p>Elefteria (Elia) Psillakis is a Professor in Water Chemistry at the School of Chemical and Environmental Engineering, Technical University of Crete, Greece. She is Editor-in-Chief of the Journal "<i>Advances in Sample Preparation</i>", Elsevier, Head of the Sample Preparation Network of the EuChemS-Division of Analytical Chemistry, and the Founder and Director of ExtraTECH Analytical Solutions, a spin-off company of the Technical University of Crete. From 2014–2016, she was the Vice Rector of Academic Affairs and Research at the Technical University of Crete.</p><p><strong>Presenter:</strong> Lucy Hearn (Application Specialist, Markes International)</p><p>Lucy Hearn received an MSc in Green Chemistry and sustainable industrial technologies from the University of York, UK, where her final-year project focused on the extraction and isolation of cannabinoids from hemp using supercritical CO<sub>2</sub> and Starbons. She later took up the role of application specialist at Markes, providing technical and application support to users around the world and developing applications using extraction and enrichment techniques for GC–MS.</p></blockquote>

Separation Science: Sorptive Extraction Fundamentals and Applications: Extracting More with SPME and HiSorb

Sorptive Extraction Fundamentals and Applications: Extracting More with SPME and HiSorb

We will focus on evolving microextraction methods, including SPME, thin-film SPME, SPME Arrow, vacuum-assisted SPME, and HiSorb.

Extracting More with SPME and HiSorb

<p><strong>Hear about the latest advancements in translational proteomics and metabolomics. From the molecular mechanisms of disease pathology to the latest technological developments in diagnostics and treatment.</strong></p><h5><strong>Key Learning Objectives:</strong></h5><ul><li>Spatial proteomics to assess health and diseases</li><li>Absolute quantitation of human proteins</li><li>The latest innovations in proteomics and metabolomics instrumentation and data analysis</li><li>Biomarker-guided precision medicine</li></ul><h4><strong>Day 2 – October 31</strong></h4><h5><strong>15:00 – 15:50 GMT: A Novel Strategy for the Absolute Quantification of Human Proteins</strong></h5><ul><li>Christoph Borchers, PhD (McGill University)</li></ul><h5><strong>15:50 – 15:55 GMT: </strong>Networking Break</h5><h5><strong>15:55 – 16:15 GMT: From Single Cells to the Metaproteome: Latest Developments in timsTOF Technology for Proteomics</strong></h5><ul><li>Matt Willetts, PhD (Bruker)</li></ul><h5><strong>16:15 – 16:20 GMT: </strong>Networking Break</h5><h5><strong>16:20 – 17:10 GMT: Single-Cell Chromatin Proteomics to Investigate the Biology of Exceptional Longevity</strong></h5><ul><li>Simone Sidoli, PhD (Albert Einstein College of Medicine)</li></ul><h5><strong>17:10 – 17:15 GMT: </strong>Networking Break</h5><h5><strong>17:15 – 17:35 GMT: Optimizing Metabolomics Workflows: From Sample Preparation to Multi-omics Integration</strong></h5><ul><li>Hagen Magnus Gegner, PhD (CTC Analytics)</li></ul><h5><strong>17:35 – 17:40 GMT:</strong> Networking Break</h5><h5><strong>17:40 – 18:10 GMT: Analyzing Metabolic Responses to a Standardized Meal Challenge Using Exhaled Breath</strong></h5><ul><li>Matteo Tardelli, PhD (Owlstone Medical)</li></ul><h5><strong>18:10 GMT: </strong>Event Close</h5><h5><strong>Who Should Attend:</strong></h5><ul><li>Scientists and researchers seeking to expand their knowledge</li><li>Pharmaceutical and biotech professionals driving drug development</li><li>Clinicians looking to improve patient care</li><li>Academicians exploring new research avenues</li><li>Graduate students and postdoctoral fellows building their careers</li></ul><blockquote><p><strong>Presenter: </strong>Mathias Uhlén, PhD (Professor, KTH - Royal Institute of Technology)</p><p><strong>Presenter:&nbsp;</strong>Christoph Borchers, PhD (Professor, McGill University)</p><p><strong>Presenter:</strong>&nbsp;Janne Lehtiö, PhD (Professor, Karolinska Institutet)</p><p><strong>Presenter:</strong>&nbsp;Crystal Montoya (Senior Marketing Product Manager, Miltenyi Biotec)</p><p><strong>Presenter:</strong>&nbsp;Kari Basso, PhD (Director of Mass Spectrometry Research and Education, University of Florida)</p><p><strong>Presenter:&nbsp;</strong>Fabian Coscia, PhD (Group Leader, Max Delbrück Center)</p><p><strong>Presenter:</strong>&nbsp;Simone Sidoli, PhD (Assistant Professor, Albert Einstein College of Medicine)</p><p><strong>Presenter:</strong>&nbsp;Hagen Magnus Gegner, PhD (Content and Digital Marketing, CTC Analytics)</p><p><strong>Presenter:</strong>&nbsp;Matt Willetts, PhD (Proteomics Applications Manager, Bruker Daltonics)</p><p><strong>Presenter:&nbsp;</strong>Matteo Tardelli, PhD (Senior Biomarker Scientist, Owlstone Medical)</p><p><strong>Presenter:&nbsp;</strong>Aaron Gajadhar, PhD (Director, Strategic Applications, Seer)</p><p><strong>Presenter:&nbsp;</strong>Gary Siuzdak, PhD (Professor and Senior Director, Scripps Research Institute)</p></blockquote>

Technology Networks: Advances in Proteomics & Metabolomics 2024

Advances in Proteomics & Metabolomics 2024 (Day 2)

Hear about the latest advancements in translational proteomics and metabolomics. 

Advances in Proteomics & Metabolomics 2024  (Day 1)

<div pardot-region="webinar-information" pardot-region-type="pardot" id="description" data-id="29767" data-hml-enabled="1"><p><strong>LECO will regularly invite key leaders of the NTS space from all industries to present and discuss their groundbreaking work. This series promises not only to delve deeper into the intricacies of non-targeted screening but also to foster collaboration and knowledge exchange among experts and enthusiasts alike. Secure your spot now and embark on a journey of discovery in chemical analysis, with each instalments of our monthly webinar series delivering fresh perspectives and invaluable insights.</strong></p></div><div pardot-region="speaker-information" pardot-region-type="pardot" id="speakers" data-id="29770" data-hml-enabled="1"><div><div><p>In his talk, Prof. Zoccali&nbsp;will explore the pioneering applications of Comprehensive Two-Dimensional Gas Chromatography coupled with Time-of-Flight Mass Spectrometry in the analysis of extra virgin olive oil (EVOO), measured on our newly released Pegasus BTX GCxGC-ToF MS.</p><p>He will demonstrate how this advanced technique provides insights in both targeted and non-targeted analyses , offering deeper understanding&nbsp;into EVOO's chemical profiles. Dr. Zoccali will also highlight how GCxGC-ToF MS enhances the detection of contaminants and key compounds, such as antioxidants and sterols, which are essential for assessing quality, authenticity and flavor.</p><p>Don't miss this opportunity to gain valuable knowledge from an expert in food analysis.&nbsp;</p><blockquote><p><strong>Presenter:</strong> Professor. Mariosimone Zoccali (University of Messina, Italy)</p><p>Joining us from the University of Messina, Mariosimone Zoccali, Assistant Professor of Analytical Chemistry, will present on 'Boosting Food Analysis Using GCxGC-ToFMS.&nbsp;</p></blockquote></div></div></div>

LECO: Non-Targeted Screening in Food: Boosting Food Analysis using GC×GC-ToF MS

Non-Targeted Screening in Food: Boosting Food Analysis using GC×GC-ToF MS

Applications of GCxGC coupled with TOF MS in the analysis of extra virgin olive oil (EVOO), measured on our newly released Pegasus BTX GCxGC-ToF MS.

Boosting Food Analysis using GC×GC-ToF MS

<p><strong>Following up from our very successful previous sessions, we are delighted to offer another panel discussion in the ever-popular “Ask the Agilent Experts” series.</strong></p><p><strong>Have you ever had a question about your GC/GCMS analysis and thought, “I have no idea what to do,” or that since the question seemed so simple, everyone must already know the answer and “Am I the only one who doesn’t know what to do?” We can assure you that you are not alone.</strong></p><p>If you have a question, we can guarantee that you are not the first…nor the last person to ask the question, especially when it comes to gases. Sometimes the simplest of questions can have the most complex answers. A question about the leaks on your mass spectrometer can lead to a discussion about how gas quality impacts sensitivity. A question about what to do when converting a method from helium to hydrogen carrier gas can lead to a discussion about column dimensions, column bleed, and what thermal stability means. There’s no such thing as an easy answer because the answer always depends on many different factors.</p><p>Experts from Agilent, as well as from the field, will discuss some of the most frequently asked questions about GC and GCMS (which may seem like simple questions but have anything but simple answers). We'll also answer new questions that we hope you will submit to us.</p><p><strong>By attending this webinar, you will learn:</strong></p><ul><li>How different carrier gases impact results and what to consider when converting methods from one carrier gas to another.</li><li>What is column bleed, how it relates to thermal stability, how your carrier gas can impact it, and why it matters even when using selective detectors like mass specs.</li><li>What is the difference between gas cylinders and gas generators, and should you consider using gas saving measures when using a generator.</li></ul><p><strong>What you need to know:</strong></p><p><strong>Date: 7th November, 2024</strong></p><p><strong>Start times:</strong></p><ul><li>Broadcast #1: 7th November - 7:00 PST (Los Angeles) / 9:00 CST (Chicago) / 10:00 EST (New York) / 15:00 GMT (London) / 16:00 CET (Paris/Berlin)</li><li>Broadcast #2: 7th November - 11:00 PST (Los Angeles) / 13:00 CST (Chicago) / 14:00 EST (New York)</li><li>Broadcast #3: 8th November - 8:30 IST (New Delhi) / 11:00 SGT (Singapore) / 11:00 CST (Shanghai) / 12:00 JST (Tokyo) / 14:00 AEDT (Sydney) / 16:00 NZDT (Auckland)</li></ul><p>Duration: Approximately 60 minutes</p><blockquote><p><strong>Presenter:</strong> Vanessa Abercrombie (MFS, GC Applications Chemist, Agilent Technologies)</p><p>Vanessa Abercrombie is a GC applications chemist at Agilent Technologies in Folsom, California, USA. Vanessa has a broad background in GC and GC/MS, including experience as an instrument chemist at Bode Technology in Virginia working under contract to the FBI’s Laboratory Division. Prior to that, Vanessa worked for ETS Labs in St. Helena, California, as an analytical chemist, where she researched and developed quantitative separations by GC/MS and UHPLC for beer, wine, and spirits. She holds a Masters of Forensic Science from The George Washington University and a Bachelor of Arts in Chemistry from Sonoma State University.</p><p><strong>Presenter: </strong>Ed Connor (Product Manager, PEAK Scientific Instruments)</p><p>Ed joined PEAK in 2013 as a GC product specialist and then moved to product management. He’s been working on many collaborative projects with PEAK customers and major instrument manufacturers worldwide. The main focus of these collaborations has been looking at conversion from helium to hydrogen carrier gas for GC applications. Ed completed his Dr.Sc. at ETH Zurich in 2007 using GC-MS to look at herbivore-induced plant volatiles and their interaction with beneficial insects. He then joined the University of Zurich where his work focused primarily on floral volatile analysis using a variety of volatile collection methods, GC-MS, and GC-FID.</p><p><strong>Moderator: </strong>Diane Turner (Director &amp; Senior Consultant, Anthias Consulting Ltd)</p><p>A Warwick University graduate, Diane completed her Master's in analytical chemistry and started her career in environmental chemistry, later gaining significant experience as an applications chemist. Diane’s area of research through her PhD studies at The Open University was disease diagnosis. She has developed methods and given support and training for companies in most industries around the world for more than 20 years. Diane holds voluntary roles with The Royal Society of Chemistry and other scientific organizations.</p></blockquote>

Separation Science: Ask the Agilent Experts Series – Part 6: The Gas Edition

Ask the Agilent Experts Series – Part 6: The Gas Edition

GC and GC/MS scientists discuss and answer more of your most frequently asked questions.

GCMS webinars focusing on GC/MS - page 16