EU Regulation 396/2005: Pesticide Residue Testing and the Critical Role of QuEChERS Evaporation in Food Safety

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 4th May 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you application note by Shimadzu, presentation by MDCW / JEOL and technical note by Thermo Fisher Scientific!<h3>1. MDCW / JEOL: Flow-Modulated GCxGC-QMS Analysis Without Splitting Off the GC Flow</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_16_Jensen_11e29d5022.pdf">Full PDF for download</a></li></ul><section><div><div><div><div><div><div>This presentation by Kirk Jensen (JEOL USA) explores the feasibility of performing flow-modulated comprehensive two-dimensional gas chromatography (GC×GC) coupled with quadrupole mass spectrometry (QMS) without splitting the GC flow, which is traditionally required to protect MS systems from high carrier gas flows. The core concept builds on GC×GC, where compounds are separated using a primary and secondary column connected via a modulator, significantly increasing separation power compared to one-dimensional GC. The presentation contrasts thermal modulation (offering sharper peaks and higher theoretical sensitivity but requiring cryogenic cooling) with flow modulation, which avoids cryogens, handles volatile analytes well, and is more flexible, but typically demands higher gas flows that standard MS systems cannot tolerate .To address this limitation, the study utilizes the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=24&amp;search=JMS-Q1600GC">JEOL JMS-Q1600GC</a> UltraQuad quadrupole GC-MS system, which can accept unusually high carrier gas flows (up to ~20 mL/min), enabling direct coupling with a SepSolve INSIGHT flow modulator without splitting the effluent . The analytical setup includes dual GC columns (e.g., Zebron ZB-5MSplus for the first dimension and BPX50 for the second), high secondary flow rates (~25 mL/min), and electron ionization (EI) MS detection. Additional system components include optional FID detection, bleed line control, and ChromeSpace software for data processing . This configuration allows full analyte transfer into the MS, eliminating the need for flow splitting and potentially improving detection efficiency.Experimental results demonstrate the applicability of this approach to complex mixtures, including a pesticide mixture containing over 200 compounds and real-world samples such as perfumes and fuels. The GC×GC-MS system produced detailed two-dimensional chromatograms with high spectral quality, enabling the correct identification of approximately 120 compounds despite relatively moderate spectral match factors . Comparisons at different flow rates (e.g., 25 vs. 50 mL/min) showed that spectral integrity and compound identification remain robust, indicating that higher flow operation does not significantly compromise MS performance.In conclusion, the work demonstrates that flow-modulated GC×GC-QMS without flow splitting is feasible, provided that the MS system can tolerate high carrier gas flows. While further optimization is needed (e.g., column selection, inlet pressure, and separation conditions), the approach offers a practical alternative to thermal modulation by eliminating cryogens and simplifying operation. Future work will focus on improving sensitivity, optimizing separations, and exploring alternative carrier gases such as hydrogen to reduce costs and expand applicability</div></div></div></div></div></div></section><h3>2. Shimadzu: Detailed Hydrocarbon Analysis by Nexis GC-2030 Using ASTM D6730</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00863_en_eb633bc741.pdf">Full PDF for download</a></li></ul><h5>User Benefits</h5><ul><li>Detailed compositional analysis of gasoline in accordance with ASTM D6730 is feasible using the Nexis GC-2030.&nbsp;</li><li>By employing PONAsolution, a PONA/DHA analysis software, laborious identification tasks can be reduced, and quantitation calculations and report generation can be performed automatically.</li></ul>ASTM D6730 specifies the analysis of hydrocarbons in gasoline and oxygenates such as ethanol, methyl tert-butyl ether (MTBE), and ethyl tert-butyl ether (ETBE) over a boiling point range up to 225 ̊C. Identification and quantification of individual compounds in gasoline are critically important for refinery process control and product quality assurance. In this application news, we report compositional analysis of gasoline conforming to ASTM D6730 using the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Nexis+GC-2030">Nexis GC-2030 gas chromatograph</a>. Gasoline typically comprises over 100 hydrocarbons, making identification tasks highly complex; however, PONAsolution, a PONA/DHA analysissoftware,simplifies this process.<h4>PONAsolution</h4>PONAsolution Ver.6 provides retention index libraries for each relevant standard (ASTM D6730, D6729, D5134, D6733). Identification of n-alkanes automatically corrects the retention times of the remaining several hundred components, thus streamlining the identification process. When only a specific retention region requires adjustment, the two-point identification function is useful (Fig. 1). In the two-point identification procedure, reference and sample chromatograms are compared while assigning corresponding peaks. First, click on an identified component mark in the reference data (Fig. 1, a), then click the matching sample peak (Fig. 1, b). Repeat this for a second pair of peaks. The retention times of components between these two anchor points are then automatically corrected.<h4>Conclusion</h4>Compositional analysis of gasoline in accordance with ASTM D6730 was performed. The combination of SH PONA Tuning Column and SH-1 PONA main column enabled separation of compounds with closely spaced retention times. Moreover, use of PONAsolution software greatly simplifies complex identification tasks.<h3>3. Thermo Fisher Scientific: Fiber optic probes add flexibility to Raman chemical analysis</h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/drx3_flex_tech_note_tn54708_bebb56b870.pdf">Full PDF for download</a></li></ul>Fourier Transform Infrared Spectroscopy (FTIR) and Raman Spectroscopy are non-destructive analytical techniques that rely on the interaction of electromagnetic radiation with molecular vibrations to provide information about the chemical composition and structure of a sample. Despite their similarities, there are some distinct differences between the two techniques. In principle, FTIR is based on the absorption of infrared radiation by molecules and measures changes in dipole moment during molecular vibrations. Raman spectroscopy, on the other hand, is based on the inelastic scattering of monochromatic light and measures changes in polarizability during molecular vibrations.&nbsp;When applied to bulk chemical analysis, both FTIR and Raman spectroscopy can be used to analyze solids, liquids, and gases, but the nature of Raman spectroscopy lends some unique sampling advantages. Additionally, Raman often requires little to no sample preparation. Presented herein are application examples that highlight some of the sampling advantages of Raman spectroscopy. All the spectral data in this technical note were collected using a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2238">Thermo Scientific™ DXR3 Flex Raman Spectrometer</a> equipped with a fiber optic probe. (Fiber optics are readily available for Raman spectroscopy because of the use of visible and NIR light and do not require the exotic materials associated with FTIR fiber optics.) Preliminary tests for all samples were carried out using both 532 nm and 785 nm excitations, and it was determined that the 785 nm laser set gave an overall better balance between fluorescence and Raman scattering efficiency.<h4>Summary&nbsp;</h4>In this technical note, the analyses of a variety of samples by Raman spectroscopy are demonstrated. All samples were analyzed without sample preparation.&nbsp;<ul><li>Precise and localized analysis at the focal point of the Raman-exciting laser allows sampling through glass bottles, blister packaging and plastic containers, which eliminates possible cross contamination and analyst exposure to hazardous materials. The contributions from the packaging and containers depend on the type of container material, the container thickness, and the materials’ chemical compositional complexity, but these contributions can be readily subtracted out when needed.&nbsp;</li><li>Water is a weak Raman scatterer. Raman therefore has reduced water sensitivity, making it a preferred technique for aqueous solution analysis over FTIR. As demonstrated in the analysis of an energy drink, the Raman bands from water can be subtracted from the spectrum of the aqueous solution, leading to the identification of the components of the solution.&nbsp;</li><li>Raman spectroscopy is well suited for the analysis of inorganic materials, especially in identifying the crystal phases and polymorphs, as demonstrated by the analyses of minerals and pigments in a painting.&nbsp;</li><li>Fiber optic probes provide flexibility and ease of maneuverability. This is particularly advantageous when analyzing samples that are difficult to access or manipulate, such as large containers, geological samples and paintings</li></ul>The DXR3 Flex has multiple sampling options available. A properly configured fiber-optic probe is arguably the most versatile accessory for the analysis of bulk solids and liquids. The advantages, both from those inherent to Raman spectroscopy and those resulting from the use of fiber optic probe, provide opportunities for a wide variety of different applications when using the DXR3 Flex Raman Spectrometer.

News from LabRulezGCMS Library - Week 19, 2026

🎤Francis Femi OloyIn this episode of Concentrating on Chromatography, David speaks with Francis Femi Oloy about using chromatography to uncover hidden pollutants in real-world water systems.Femi’s team analyzed polychlorinated biphenyls (PCBs) in six major rivers in southwestern Nigeria — compounds that were banned decades ago but still persist in the environment. Using a workflow that many analytical labs will recognize — liquid–liquid extraction, cleanup, rotary evaporation, nitrogen blowdown, and GC-ECD detection — they quantified 25 PCB congeners at trace levels and linked the results to ecological and human health risk.<h4>In this conversation, we cover:</h4><ul><li>Why legacy pollutants like PCBs still show up today</li><li>Choosing GC-ECD vs LC-MS for halogenated compounds</li><li>Liquid–liquid extraction and matrix cleanup strategies</li><li>Why sample concentration is critical for dilute environmental samples</li><li>How rotovap + nitrogen blowdown work together without losing volatile analytes</li><li>Seasonal trends (why wet season levels were higher)</li><li>Translating concentration data into meaningful risk assessments</li></ul><h3>Video Transcription</h3><section><div><div><div><div><div><div>Persistent organic pollutants such as polychlorinated biphenyls (PCBs) remain a significant environmental concern despite decades of regulatory restrictions. In this interview, Francais Femi Oloy discusses the environmental and analytical challenges associated with monitoring PCB contamination in rivers of southwestern Nigeria, a rapidly industrializing region where urban growth, industrial activity, agriculture, and dense populations intersect with extensive aquatic systems.Oloy explains that his interest in environmental contaminant analysis emerged from observing unexplained health problems and environmental degradation while growing up in Nigeria. This motivated his transition into organic and environmental chemistry, with a focus on identifying pollutants present in drinking water, agricultural soils, and food systems. Southwestern Nigeria, particularly the Lagos region, represents a critical environmental monitoring area due to intense industrial development, shipping activity, and widespread human dependence on rivers for domestic use, agriculture, and fishing.Although PCBs are considered “legacy pollutants” and are no longer intentionally produced, the interview highlights why they continue to persist in aquatic environments. Old electrical transformers and aging industrial equipment still contain PCB residues, while historical contamination stored in river sediments can become remobilized during flooding, dredging, or sediment disturbance. Because PCBs are hydrophobic and resistant to degradation, they preferentially accumulate in sediments and bioaccumulate through aquatic food chains, creating long-term environmental and human exposure risks.A major focus of the discussion centers on the analytical workflow used for PCB determination in environmental water samples. Composite river water samples were collected in amber glass bottles to avoid contamination and photodegradation, preserved with sodium azide to minimize microbial activity, and stored under cooled conditions prior to extraction. The analytical protocol employed liquid–liquid extraction using dichloromethane (DCM) and hexane to recover both polar and nonpolar PCB congeners. Oloy emphasizes that liquid–liquid extraction was selected over solid-phase extraction (SPE) because of concerns about congener retention within sorbent materials and clogging issues associated with large-volume environmental samples.Following extraction, concentration and cleanup represented critical analytical stages due to the trace-level occurrence and volatility of PCBs. Silica and alumina cleanup procedures were used to remove matrix interferences prior to instrumental analysis. The concentration workflow combined rotary evaporation for bulk solvent reduction with nitrogen blowdown for final volume reduction to less than 1 mL, while carefully avoiding excessive temperature or complete dryness to minimize analyte loss. Oloy repeatedly stresses that improper concentration procedures are among the most common causes of analytical failure in PCB analysis.For instrumental determination, the study utilized gas chromatography coupled with electron capture detection (GC-ECD) rather than LC-MS or GC-MS. According to Oloy, GC was preferred because PCBs are sufficiently volatile for gas chromatographic separation, while ECD provided superior sensitivity and selectivity for chlorinated compounds at environmentally relevant concentrations. The interview also discusses analytical validation strategies, including the use of surrogate standards to assess recoveries, which ranged from approximately 85% to 114%, and signal-to-noise-based determination of detection limits.The study further examined seasonal variations in PCB concentrations, revealing higher levels during the wet season. This observation was attributed to rainfall-driven runoff from contaminated infrastructure, sediment resuspension, and lower temperatures that reduce volatilization losses. To communicate toxicological relevance beyond simple concentration reporting, the researchers also calculated toxic equivalency values (TEQs), converting mixtures of PCB congeners into biologically meaningful toxicity estimates comparable to dioxin toxicity metrics.Beyond environmental monitoring, Oloy highlights broader research interests focused on pollutant remediation and sustainable environmental protection. His group is also involved in developing catalytic materials capable of degrading or removing persistent contaminants from environmental systems. Throughout the discussion, he emphasizes that analytical chemistry plays a central role not only in detecting pollutants, but also in enabling prevention, remediation, and long-term environmental management strategies.</div></div></div></div></div></div></section><blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Tracking Toxic PCBs in River Water using Gas Chromatography–Electron Capture Detection

Article

Product

Application

Video

Scientists

Environment

Food

Presentation

Interview

Science and research

Laboratories

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Separation Science

Agilent Technologies

Phenomenex

Thermo Fisher Scientific

Wasson-ECE Instrumentation

Wiley

SciY/Mestrelab Research

Have you ever seen analyte peaks show up in a blank, or extra peaks suddenly appear out of nowhere?
It is likely that you have some carryover or contamination in your system. Contamination that creates ghost and carryover peaks can be introduced at different points, including sample preparation, introduction, and separation. The additional peaks can cause false positive identifications and/or inaccurate quantitative results. 
Join us as we discuss the most common sources of carryover and how to address them.
<blockquote>
Presenter: Alex Ucci (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.
</blockquote>

Agilent Technologies: Don’t Get Carried Away by Carryover: Troubleshooting GC Chromatography

Don’t Get Carried Away by Carryover: Troubleshooting GC Chromatography

The most common sources of carryover and how to address them.

Troubleshooting GC Chromatography

<h3>PhenoAcademy Webinars - Gas Chromatography Series</h3>
<h4>Gas Chromatography Tips and Tricks</h4>
<ul>
<li>Find new best practices for gas management, and how to keep your system clean
</li>
<li>Identify active sites and impurities within the column and system
</li>
<li>Learn how to properly cut your column, and make the best connections
</li>
</ul>
<blockquote>
Presenter: Duilio Romanello (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Duilio Romanello graduated with his Bachelors of Science in Pharmaceutical Chemistry and Technology from University of Bologna. Duilio then joined Phenomenex in 2008 as an Inside Technical Sales Consultant becoming Team Leader in Italy for GC/SPE in 2010 and then for the Environmental &amp; Food Team.
</blockquote>
<blockquote>
Since 2016 he has been covering the role of Account Manager for the South of Italy working remotely and acting as GC Specialist. Since November 2023 he is Senior Technical Specialist for the Technical team at Phenomenex.
</blockquote>
<blockquote>
Presenter: Zachary Woodward (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Zachary Woodward is a Senior Technical Specialist with Phenomenex, Inc, assisting laboratories with method development in the bio-pharma, environmental, and food industries. Zachary spent his formative years developing HPLC and GC methods with a pharmaceutical lab in Albany, NY, after which he developed HPLC and SPE methods in the clinical setting here in Southern California. Zachary received his B.Sci. in Chemistry from the College of William and Mary, was awarded his Master’s in Chemistry at San Diego State University, and is happy to speak with you today!
</blockquote>
<blockquote>
Presenter: Lucia Geis Asteggiante (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Lucia is a Senior Technical Specialist that has recently joined Phenomenex’s Global Technical Team. She has a broad experience in the field of Analytical Chemistry with a particular focus on LC chromatography coupled with mass spectrometry. Lucia comes from a strong academic and regulatory background with experiences ranging from method development and analysis of small molecules to large protein complexes. She gained her Ph.D. at the University of Maryland - College Park, USA and did her post-doctoral work at the University of Oxford, UK. During her time as a researcher, she has authored/co-authored 23 scientific publications and 2 book chapters.
</blockquote>

Gas Chromatography Tips and Tricks

Find new best practices for gas management, and how to keep your system clean

Gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) have been in use for more than 60 years, consistently meeting the analytical performance demands of labs around the world.
With the ever-changing landscape of laboratory and analyst needs, instrument usability and space requirements are an acute focus and highly prioritized.
This webinar will highlight the maintenance operation critical to keeping your GC and GC-MS systems healthy. Along with these tips and tricks, this demonstration will also display how Shimadzu has reshaped the Brevis GC-2050 and GCMS-QP2050 to fit challenging laboratory requirements with simple operation, compact design, built-in analytical intelligence, and best-in-class performance.
By attending this presentation, you will learn:
<ul>
<li>maintenance tips for GC and GC-MS from experts</li>
<li>how built-in analytical intelligence can support high-throughput laboratory operations</li>
<li>how high-performing systems can optimize your workflow</li>
</ul>
<blockquote>
Presenter: Ryo Takechi (Global GC Product Manager, Shimadzu Corporation)
</blockquote>
<blockquote>
Ryo Takechi majored in chemical engineering from Doshisha University in Kyoto, Japan, and now has more than ten years of experience in gas chromatography and engineering of analytical instrumentation.
</blockquote>
<blockquote>
Presenter: Alan Owens (GC and GC-MS Product Manager, Shimadzu Scientific Instruments, Inc.)
</blockquote>
<blockquote>
Alan Owens is the GC and GC-MS Product Manager at Shimadzu Scientific Instruments. Alan joined Shimadzu in 2016 with a bachelor’s degree in biology and chemistry as a GC-MS product specialist before ascending to the role of product manager in 2021 for GC-MS and 2023 for GC. With over a decade of hands-on experience, Alan has established himself as a distinguished authority in gas chromatography and gas chromatography-mass spectrometry.
</blockquote>

Separation Science: Ensure the Optimal Performance of Your GC/GC-MS: Tips and Features of the Brevis GC-2050 and GCMS-QP2050

Ensure the Optimal Performance of Your GC/GC-MS: Tips and Features of the Brevis GC-2050 and GCMS-QP2050

This webinar will highlight the maintenance operation critical to keeping your GC and GC-MS systems healthy.

Tips and Features of the Brevis GC-2050 and GCMS-QP2050

Intelligent GCs simplify life inside - and outside - the lab.
Agilent&#39;s intelligent GCs are equipped with robust diagnostic and troubleshooting functions, aimed at minimizing operational downtime. These functionalities are not only accessible locally but can also be efficiently utilized remotely through the built-in browser interface on the Agilent 8860, 8890, and Intuvo 9000 GCs. During our session, we’ll demonstrate specific instances to illustrate how these GCs effectively identify issues and how remote access allows you to address them independent of your proximity to the system. 
When you enable remote operations, you enable faster issue resolution, optimization of your technical resources, and creation of a scalable model for managing instrument schedules and productivity. Why lose time moving your experts from system to system when they could assist technicians in nearby rooms, adjacent buildings, or even across continents from a single location? Join us to explore the extensive diagnostic capabilities of your Agilent GC and bring your queries for an in-depth Q&amp;A discussion.
<blockquote>
Presenter: Jamie Wetuski (Global GC Training Specialist, Agilent Technologies)
</blockquote>
<blockquote>
Jamie Wetuski is the Global GC Training Specialist on the Technical Marketing Team at Agilent Technologies, where she focuses on assisting customers with achieving their GC goals. She began her career at Agilent in the Gulf Coast as a Field Support Scientist servicing Agilent GC/GCMS systems. Jamie received a B.S.in Chemistry from Fort Lewis College in Durango, Colorado and an M.S. in Analytical Chemistry from Illinois Institute of Technology.
</blockquote>
<blockquote>
Presenter: Abbey Fausett (Applications Scientist, Gas Phase Separations Division, Agilent Technologies)
</blockquote>
<blockquote>
Abbey Fausett is an applications scientist within Agilent’s Gas Phase Separation Division. Her responsibilities include developing methods for emerging markets, proving existing methods on new systems, and creating material focused on new features within GC and GCMS systems. Before joining Agilent in 2011, she was an Agilent customer for 10+years, tasked with multi-technique method development, validation, and troubleshooting.
</blockquote>

Agilent: Diagnostics From Your Desk, Troubleshooting From Your Kitchen Table

Diagnostics From Your Desk, Troubleshooting From Your Kitchen Table

Join us to explore the extensive diagnostic capabilities of your Agilent GC and bring your queries for an in-depth Q&A discussion.

Agilent GC Diagnostics and Troubleshooting webinar

Selecting the best GC for you
<blockquote>
Presenter: John Wasson
</blockquote>
<blockquote>
John Wasson has over 40 years of experience in Gas Chromatography and Chemical Instrumentation. He is President of Wasson-ECE Instrumentation, Inc.
</blockquote>

Wasson-ECE Instrumentation: Selecting the Best GC

Selecting the Best GC

Webinar will cover the following topic: Selecting the best GC for you

Purge &amp; Trap technology is often used to achieve the legal detection limits of volatile and very volatile organic compounds in water samples. Especially in case of water intended for human consumption, the regulatory requirements are particularly stringent. When dealing with more complex matrices, headspace analysis offers a much cleaner approach compared to purging the sample. However, sensitivity could be limited without a suitable enrichment of the analytes before injection.
The technological developments in recent years on new headspace extraction/enrichment techniques, such as ITEX (In Tube Extraction), makes possible to achieve low detection limits for volatiles with a clean sampling approach, without purging. Different adsorbents can be used for ITEX depending on the analytical demand. Additionally, a suitable refocusing before transferring the sample into the chromatography column, provides narrow peaks, better signal-to-noise and enhanced sensitivity especially for very volatile organic compounds (VVOCs). This webinar gives an insight of the available technology along with various examples from a routine laboratory.
<h5>Who should attend:</h5>
<ul>
<li>Laboratory manager of environmental testing laboratories</li>
<li>Analysts who have to detect trace levels of VOCs and VVOCs in water</li>
<li>Analysts looking for a clean and sensitive sampling techniques for VOCs and VVOCs in water</li>
</ul>
<blockquote>
Presenter: Daniela Cavagnino (Product Marketing Manager, GC &amp; Autosampler, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Dr. Daniela Cavagnino received a Master Degree in Chemistry at the University of Milan, Italy. She started her career in gas chromatography at Thermo Fisher Scientific spending several years in the R&amp;D laboratories working on GC technology innovation and more than 15 years in product and marketing management roles promoting GC/GC-MS technology and applications.
</blockquote>
<blockquote>
Presenter: Petra Gerhards (Regional Marketing Manager EMEA GC &amp; GC-MS, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Petra Gerhards is a Regional Marketing Manager of GC and GC-MS at Thermo Fisher Scientific. She has more than 29 years of experience in the fields of GC-MS, SPE and LC-MS. Since joining the regional team, she has contributed to workflow solutions combining vials and closures with SPE solutions, GC-MS and LC-MS.
</blockquote>

ThermoFisher Scientific: Improvements for the analysis of very volatile organic compounds (VVOC) using static and dynamic headspace

Improvements for the analysis of very volatile organic compounds (VVOC) using static and dynamic headspace

Insight of the available technology for headspace extraction/enrichment techniques, such as ITEX, along with various examples from a routine laboratory.

Analysis of VVOC using static and dynamic headspace

In this session, discover how Wiley’s <a href="https://gcms.labrulez.com/products/1016">KnowItAll</a> saves hours of GC-MS manual analysis time by combining fast, flexible deconvolution with an integrated reference database search into a single, automated workflow to identify components.
In this session we will demonstrate through a series of live examples:
<ul>
<li><a href="https://gcms.labrulez.com/products/1016">KnowItAll’s</a> various <a href="https://gcms.labrulez.com/products/1020">methods for GC-MS analysis</a> and how they can impact your workflow. </li>
<li>How <a href="https://gcms.labrulez.com/products/1016">KnowItAll</a> is optimized for searching and review popular <a href="https://gcms.labrulez.com/products?category=249&amp;search=Wiley">GC-MS libraries</a>, such as the <a href="https://gcms.labrulez.com/products/886">Wiley Registry 2023</a>, <a href="https://gcms.labrulez.com/products/884">NIST</a>, <a href="https://gcms.labrulez.com/products/937">MMPW</a>, or <a href="https://gcms.labrulez.com/products/939">MS of Designer Drugs</a>.</li>
</ul>
This session is recommended for:
<ul>
<li>Scientists and chemists who use mass spectrometry or are interested in learning more about our capabilities. </li>
<li>Professors and students engaged in chemistry and mass spectrometry courses or lab work.</li>
</ul>
About KnowItAll:
KnowItAll combines all the tools and spectral databases you need for effective analysis into a single, easy-to-use interface to make your lab its most efficient. Compatible with over 130 instrument formats, it streamlines your entire workflow regardless of how many techniques and instruments you use. Learn more at <a href="sciencesolutions.wiley.com">sciencesolutions.wiley.com</a>
<blockquote>
Presenter: Dr. Leanna Ergin
</blockquote>
<blockquote>
Dr. Leanna Ergin is an Assistant Editor for Wiley Science Solutions, for which she helps create tools for spectroscopy, structural, and scientific standard reference data and helps create innovative software applications. Leanna completed her PhD in Clinical-Bioanalytical Chemistry from Cleveland State University, where she developed a protocol for processing hyperspectral image data that distinguishes the spectra, removes degeneracies caused by symmetry, and is generalized to work with any number of wavelength dimensions and spectra. The results are mapped to the full RGB colorspace of modern computer displays. Leanna joined Wiley in 2022.
</blockquote>

Wiley: Introduction to KnowItAll for Mass Spectrometry

Introduction to KnowItAll for Mass Spectrometry

Discover how Wiley’s KnowItAll saves hours of GC-MS manual analysis time

Explore advanced analytical techniques and methodologies for assessing hydrocarbon contamination in water sources, increase sample throughput and gain valuable insights into environmental monitoring. Hydrocarbons, originating from various sources such as industrial discharges, urban runoff, or natural processes, can adversely impact aquatic ecosystems. Understanding the Hydrocarbon Index is essential for safeguarding water resources, protecting ecosystems, and promoting public health and environmental sustainability.
Public environmental service providers and contract testing laboratories could greatly increase sample throughput of water samples for the analysis of total hydrocarbon index according to the method EN ISO 9377-2, thanks to an automated workflow for liquid-liquid extraction, clean-up and on-line large volume injection into the GC, through the robotic Thermo Scientific TriPlus RSH SMART Autosampler. The system is fully controlled by Thermo Scientific Chromeleon Chromatography Data System (CDS) Software. Thanks to the Intelligent Sequence and the eWorkflow functionalities, it offers a complete automated management of the samples, automated reporting and transfer to LIMS, enabling 24/7 operations with significant labor and cost saving. 
What you will learn:
<ul>
<li>How to optimize mineral oil analysis in water samples</li>
<li>How to stay compliant with ISO 9377-2 guideline</li>
<li>How to face increasing sample demand through automation</li>
</ul>
Who should attend:
<ul>
<li>Laboratory managers of environmental testing laboratories</li>
<li>Laboratory managers at water service providers</li>
<li>Analysts looking for increasing throughput for mineral oil analysis in water samples</li>
</ul>
If you have questions for our experts, please submit them during registrations or send them anytime in advance via email to analyze.eu@thermofisher.com. Live questions will be handled during the webinar in our Q&amp;A chat.
Short notice: Can&#39;t attend the live broadcast? No problem! Register anyway and you will automatically receive the link to the webinar recording.
<blockquote>
Presenter: Petra Gerhards (Regional Marketing Manager, GCMS and TEA, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Her background is over 34 years of experience in the field of GCMS, SPE and LCMS. Since joining the EMEA Regional Marketing Team for CCS in 2016, she has been involved in a lot of workflow solutions combining Vials and Closures with SPE solutions, GCMS and LCMS.
</blockquote>
<blockquote>
Presenter: Daniela Cavagnino (Product Marketing Manager, GC and Sampling Solutions, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Dr. Daniela Cavagnino received her Masters Degree in Chemistry at the University of Milan, Italy. She started her career in gas chromatography at Thermo Fisher Scientific spending several years in the R&amp;D laboratories working on GC technology innovation. Then, she conveyed her technical background into product management and marketing management roles with more than 15 years experience in promoting GC/GCMS technology and applications in several different market segments.
</blockquote>

ThermoFisher Scientific: Unlocking water quality insights: Hydrocarbon index analysis for environmental monitoring

Unlocking water quality insights: Hydrocarbon index analysis for environmental monitoring

Explore advanced analytical techniques and methodologies for assessing hydrocarbon contamination in water sources.

Water quality: Hydrocarbon index analysis

Join us for an insightful session where scientists and IT professionals from AstraZeneca come together to explore the complexities of managing analytical data within a purification lab setting. In this session, Carolina Sanchez, Senior Scientist, and Katie Proctor, Senior Scientist, will discuss the challenges of manually processing and reviewing large volumes of analytical data, and explain how automation software solutions are boosting efficiency and benefiting them in their day-to-day work. Following that, Dr. Christoph Bauer, Associate Principal Scientist, will discuss the IT architecture and integration aspects of the solution implementation.A lab with significant analytical capacity entails managing a large number of instruments and extensive analytical data on a daily basis. Within our purification labs, analytical screening data generated for compounds submitted for purification, as well as data from instrument suitability testing, was traditionally reviewed manually by an analyst to determine the most appropriate method for purification. However, this changed with the implementation of the automation solution from Mnova. The solution includes the Chrom SST brick, which monitors the performance of our instruments, and Chrom Best Method, which automatically processes the screening data and identifies the best conditions for purification, thereby freeing up analyst time.In this webinar, we will explain how these solutions fit into our day-to-day work and the benefits they have brought us. We will also discuss the IT architecture and integration aspects, the server-based processing logic, as well as the content and formats of the output.<blockquote>Presenter: Carolina Sanchez (Senior Scientist, AstraZeneca)Carolina is a chemical engineer and biotechnologist with a keen interest in data science. Since 2015, she’s been deeply involved in chromatography, getting better at developing analytical techniques for various uses. For the past four years, she’s been at AstraZeneca, working as a separation scientist where she focuses on preparative chromatography of small molecules, using both liquid and supercritical fluid chromatography methods.Presenter: Christoph Bauer (Associate Principal Scientist, AstraZeneca)Christoph holds a PhD in theoretical Chemistry and has transitioned to the field of chemoinformatics and modeling where he applies quantum chemistry, statistical analysis, and machine learning methods to chemical data within the pharmaceutical science domain. Over the past four years, he has been working in the Pharm Sci Data Science &amp; Modelling group at AstraZeneca, developing cheminformatics and computational solutions aimed at streamlining chemistry workflows.Presenter: Katie Proctor (Senior Research Scientist, AstraZeneca)Katie is a Senior Research Scientist in the Analytical and Purification group at AstraZeneca Cambridge since 2018. She has a keen interest in data science and has a focus on developing software solutions to automate system suitability assessments and analytical to purification method selection. In the lab, Katie focuses on achiral SFC and RP purification of small molecules.</blockquote>

Mestrelab Research: Automation in a purification lab at AstraZeneca

Automation in a purification lab at AstraZeneca

Session where scientists and IT professionals from AstraZeneca explore the complexities of managing analytical data within a purification lab setting.

Purge &amp; Trap technology is often used to achieve the legal detection limits of volatile and very volatile organic compounds in water samples. Especially in case of water intended for human consumption, the regulatory requirements are particularly stringent. When dealing with more complex matrices, headspace analysis offers a much cleaner approach compared to purging the sample. However, sensitivity could be limited without a suitable enrichment of the analytes before injection.The technological developments in recent years on new headspace extraction/enrichment techniques, such as ITEX (In Tube Extraction), makes possible to achieve low detection limits for volatiles with a clean sampling approach, without purging. Different adsorbents can be used for ITEX depending on the analytical demand. Additionally, a suitable refocusing before transferring the sample into the chromatography column, provides narrow peaks, better signal-to-noise and enhanced sensitivity especially for very volatile organic compounds (VVOCs). This webinar gives an insight of the available technology along with various examples from a routine laboratory.<h5>Who should attend:</h5><ul><li>Laboratory manager of environmental testing laboratories</li><li>Analysts who have to detect trace levels of VOCs and VVOCs in water</li><li>Analysts looking for a clean and sensitive sampling techniques for VOCs and VVOCs in water</li></ul><blockquote>Presenter: Daniela Cavagnino (Product Marketing Manager, GC &amp; Autosampler, Thermo Fisher Scientific)Dr. Daniela Cavagnino received a Master Degree in Chemistry at the University of Milan, Italy. She started her career in gas chromatography at Thermo Fisher Scientific spending several years in the R&amp;D laboratories working on GC technology innovation and more than 15 years in product and marketing management roles promoting GC/GC-MS technology and applications.Presenter: Petra Gerhards (Regional Marketing Manager EMEA GC &amp; GC-MS, Thermo Fisher Scientific)Petra Gerhards is a Regional Marketing Manager of GC and GC-MS at Thermo Fisher Scientific. She has more than 29 years of experience in the fields of GC-MS, SPE and LC-MS. Since joining the regional team, she has contributed to workflow solutions combining vials and closures with SPE solutions, GC-MS and LC-MS.</blockquote>

Thermo Scientific: Improvements for the analysis of VVOC using static and dynamic headspace

Improvements for the analysis of VVOC using static and dynamic headspace

Webinar on ITEX and headspace techniques for sensitive VOC and VVOC analysis in water, supporting regulatory compliance and routine environmental testing.

GCMS webinars focusing on GC - page 11