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Evaluation of Metabolite Variation by a Pooled Sample Approach between Normal Control and Traumatic Brain Injury Mice Using GCxGC-TOFMS with Data Analysis Using a Software Driven Reference Feature

 

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GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury Study John Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USA INTRODUCTION METHODS Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry has…
Key words
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Blood Serum Metabolomics Using Comprehensive Two-Dimensional Gas Chromatography High Resolution Time-of-Flight Mass Spectromery David E. Alonso, Joe Binkley, Lorne Fell, and Christina Kelly | LECO Corporation, St. Joseph, MI 10,11 17-19 Time (s) 400 600 800 1000 37 39,40 38…
Key words
hrt, hrttms, tmstrue, trueaic, aicsimilarity, similaritypeak, peakacid, acidbrain, brainformula, formulaibuprofen, ibuprofencholesterol, cholesterolformulas, formulasdatabase, databasepolar, polarpegasus
Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat Plasma John Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USA OBJECTIVES Demonstrate the enhanced detection and increased peak…
Key words
pooled, pooledobese, obeselean, leanfat, fatgcxgc, gcxgcreplib, replibtofms, tofmsuniquemass, uniquemasspool, poolname, namepools, poolsburied, buriedsimilarity, similarityresolves, resolvesglucopyranose
Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat Plasma John Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USA OBJECTIVES Demonstrate the enhanced detection and increased peak…
Key words
pooled, pooledobese, obeselean, leanfat, fatgcxgc, gcxgcreplib, replibtofms, tofmsuniquemass, uniquemasspool, poolname, namepools, poolsburied, buriedsimilarity, similarityresolves, resolvesglucopyranose
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