ISCC 2016: Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap based GC-MS
Posters | 2016 | Thermo Fisher ScientificInstrumentation
GC/MSD, GC/MS/MS, GC/HRMS, GC/Orbitrap
IndustriesPharma & Biopharma
ManufacturerThermo Fisher Scientific
Key wordsmass, closure, octanoate, extractables, deconvoluted, packaging, migrate, each, elevated, shown, scan, identification, container, figure, chromatograms, identify, tics, deforming, leachable, isolating, tentative, from, ion, ring, destined, rings, confident, peak, combination, peaks, tracefinder, impurities, components, compounds, seek, library, profiling, unique, extract, map, blank, total, accurate, spectrum, exactive, chemical, accuracy, samples, ethyl, proposed
Similar PDF
Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based GC-MS
2016|Thermo Fisher Scientific|Posters
Dominic Roberts1, Andrew Feilden2, Richard Barlow2, Jason Cole1, Alexander Semyonov1, Kyle D’Silva1, and Paul Silcock1 1 Thermo Fisher Scientific, Runcorn, UK; 2Smithers Rapra, Shawbury, UK. Poster Note 64741 Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based…
Key words
thethe, thethering, ringmass, massoctanoate, octanoatepci, pciadducts, adductstentative, tentativeforfor, forforfigure, figurewere, wereaccurate, accuratecluster, clustersamples, samplesspectrum, spectrumdeconvoluted
Confident Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap-Mass-Spectrometer-Based GC-MS
2016|Thermo Fisher Scientific|Applications
Dominic Roberts,1 Andrew Feilden,2 Richard Barlow,2 Kyle D’Silva,1 and Paul Silcock1 1 Thermo Fisher Scientific, Runcorn, UK 2 Smithers Rapra, Shawbury, UK Key Words Extractables and Leachables, Q Exactive GC, Orbitrap mass spectrometry, differential analysis, unknown identification, container closure system,…
Key words
ring, ringmass, massmatch, matchelemental, elementaltriphenylphosphine, triphenylphosphineexactive, exactivecontainer, containerclosure, closureaccurate, accurateidentification, identificationspectrum, spectrumformula, formulaaccuracy, accuracyleachable, leachablequickly
Non-targeted screening of extractables from vial septa using high-resolution Orbitrap GC-MS
2021|Thermo Fisher Scientific|Applications
APPLICATION NOTE 000206 Non-targeted screening of extractables from vial septa using high-resolution Orbitrap GC-MS Authors: Jane Cooper, Cristian Cojocariu, and Dominic Roberts Thermo Fisher Scientific, Hemel Hempstead, UK Keywords: High-resolution accurate mass, HRAM, gas chromatography, accurate mass, GC, Orbitrap Exploris…
Key words
septa, septaorbitrap, orbitrapextractables, extractablesmass, massdeconvolution, deconvolutionfid, fidexploris, explorisfrontier, frontierelemental, elementalelucidation, elucidationthermo, thermoleachables, leachablesconfident, confidentstatistical, statisticalcomposition
Analytical Workflow for Extractable and Leachable Impurities
2015|Thermo Fisher Scientific|Presentations
Analytical Workflow for Extractable and Leachable Impurities AAPS 2015 | 26 October 2015, Orlando FL Kyle D’Silva The world leader in serving science WHAT are EXTRACTABLES and LEACHABLES? 2 What is E&L testing for? 3 Areas of concern 4 CONTAMINANT…
Key words
extractables, extractablesbase, baseftms, ftmsesi, esifull, fullleachables, leachablesdiscoverer, discovererbrown, brownring, ringtracefinder, tracefinderpeak, peakwhite, whiteblack, blackabundance, abundanceexactive