Confident Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap-Mass-Spectrometer-Based GC-MS
Applications | 2016 | Thermo Fisher ScientificInstrumentation
GC/MSD, GC/MS/MS, GC/HRMS, GC/Orbitrap
IndustriesPharma & Biopharma, Materials Testing
ManufacturerThermo Fisher Scientific
Key wordsring, mass, match, triphenylphosphine, elemental, exactive, container, closure, accurate, identification, spectrum, accuracy, formula, leachable, quickly, leachables, full, identifying, pci, using, extractables, extractable, peaks, identify, chemical, parent, eliminated, compounds, scan, pharmaceutical, can, very, packaging, library, confident, unique, extract, spectral, potentially, deconvolution, fragments, toxic, propose, molecule, molecular, formulae, thermo, number, data, hits
Similar PDF
Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based GC-MS
2016|Thermo Fisher Scientific|Posters
Dominic Roberts1, Andrew Feilden2, Richard Barlow2, Jason Cole1, Alexander Semyonov1, Kyle D’Silva1, and Paul Silcock1 1 Thermo Fisher Scientific, Runcorn, UK; 2Smithers Rapra, Shawbury, UK. Poster Note 64741 Identification of Leachable Impurities from Pharmaceutical Container Closure Materials Using Orbitrap based…
Key words
thethe, thethering, ringmass, massoctanoate, octanoatepci, pciadducts, adductstentative, tentativeforfor, forforfigure, figurewere, wereaccurate, accuratecluster, clustersamples, samplesspectrum, spectrumdeconvoluted
ISCC 2016: Identification of Leachable Impurities from Pharmaceutical Container Closure Materials using Orbitrap based GC-MS
2016|Thermo Fisher Scientific|Posters
and accurate differential analysis to be performed to isolate unique features in extracts. Routine mass resolution of 60,000 FWHM and consistent sub-ppm mass accuracy ensures selective and confident compound detection and identification. POSTER NOTE Introduction The investigation of potentially toxic…
Key words
mass, massclosure, closureextractables, extractablesoctanoate, octanoatedeconvoluted, deconvolutedpackaging, packagingmigrate, migrateeach, eachelevated, elevatedshown, shownscan, scancontainer, containerfigure, figureidentification, identificationchromatograms
Analytical Workflow for Extractable and Leachable Impurities
2015|Thermo Fisher Scientific|Presentations
Analytical Workflow for Extractable and Leachable Impurities AAPS 2015 | 26 October 2015, Orlando FL Kyle D’Silva The world leader in serving science WHAT are EXTRACTABLES and LEACHABLES? 2 What is E&L testing for? 3 Areas of concern 4 CONTAMINANT…
Key words
extractables, extractablesbase, baseftms, ftmsesi, esifull, fullleachables, leachablesdiscoverer, discovererbrown, brownring, ringtracefinder, tracefinderpeak, peakwhite, whiteexactive, exactiveblack, blackhrf
High Resolution Accurate Mass GC-MS based on Orbitrap Technology - A new chapter in GC-MS
2017|Thermo Fisher Scientific|Presentations
High Resolution Accurate Mass GC-MS based on Orbitrap Technology - A new chapter in GC-MS Webinar on 25 November 2016 The world leader in serving science Overview • Introduction to the new Thermo Scientific™ Orbitrap™ GC-MS family • Insight into…
Key words
targeted, targetedorbitrap, orbitrapscan, scanscreening, screeningfull, fullmetabolomics, metabolomicsnon, nonuntargeted, untargetedunknown, unknownidentification, identificationpesticides, pesticideshrf, hrfvpi, vpiinsight, insightexactive