Scientists at IOCB Prague reveal a previously unknown mechanism that initiates gene transcription. Using cryo-EM, they uncover how alarmone molecules enable RNA synthesis under stress.

Researchers at IOCB Prague have developed new fluorogenic labels that deliver high-contrast fluorescence microscopy, enabling precise visualization of cellular processes without background noise.

Structure-guided libraries and machine learning enable faster discovery of active nucleic acid sequences beyond random mutagenesis.

Alcohol consumption produces acetaldehyde, a toxic compound that damages DNA. Scientists from IOCB Prague reveal how cells repair this damage, shedding light on the link between alcohol and cancer.

IOCB Prague is co-founding Taveren Therapeutics, a new biotech spin-off developing a novel cancer treatment strategy based on reactivating the body’s natural tumor suppressors.

Researchers at IOCB Prague developed a highly precise and ultra-stable fluorescent labeling method that stays attached even inside cells, enabling long-term, reliable tracking of biomolecules.

Dr. Petr Cígler receives the Rudolf Lukeš Prize 2025 for groundbreaking lipid and diamond nanoparticles that advance gene therapy, cancer treatment, imaging, and modern vaccine development.

IOCB Prague scientists have developed light-driven molecular motors that remain fully functional even when anchored to metal surfaces, marking a major step toward controllable nanoscale machines.

IOCB Prague scientists led by Dr. Petr Cígler developed a method to create quantum nanodiamonds within minutes—over 1,000× faster than before, paving the way for affordable large-scale nanosensor production.

The Czech PROTOCELL experiment from IOCB Prague will study protocell formation on the ISS to explore whether life could originate beyond Earth.