GCMS
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike
Author
LCGC
LCGC is the leading global provider of digital and print content to the separation science market, enhancing the productivity, efficiency, and the overall value of separation techniques globally. With our commitment to editorial excellence we have pioneered innovation across a broad portfolio of digital and print platforms. LCGC covers all key growth areas in the field of separation science by providing unbiased peer-reviewed content, educational webinars, trusted troubleshooting advice, and best-practice applications solutions. Laboratory-based analytical chemists and influential chromatographers can improve productivity and enhance their proficiency through LCGC’s practical information, giving them a competitive advantage for the real-world analysis they face.
Tags
Article
Various
Logo of LinkedIn

The LCGC Blog: Are You Sick of Hearing About ChatGPT?

We, 8.11.2023
| Original article from: The LCGC Blog/Petr Vozka
Are you getting tired of reading or hearing about ChatGPT? This blog post might give you some tips and tricks on taking advantage of ChatGPT while avoiding its application beyond its intended scope.
- **Photo:** LabRulez/AI: The LCGC Blog: Are You Sick of Hearing About ChatGPT?
  • Photo: LabRulez/AI: The LCGC Blog: Are You Sick of Hearing About ChatGPT?

ChatGPT is a language model developed by OpenAI, designed to understand and generate human-like text based on the input it receives. ChatGPT does not predict the future, solve highly technical chromatographic problems, or troubleshoot an instrument for you. So, what can ChatGPT do, and why is the entire world talking about it?

I first want to mention that I am not an AI expert (nor blogger), but rather someone who loves separations, gas chromatography, and anything that could simplify academic work. I believe ChatGPT is such a tool; however, it is sometimes misunderstood for something that it is not. Allow me to share my story with ChatGPT and some of its intriguing “tricks” with you.

In January 2023, just two months after the public release of ChatGPT, I was traveling to the 14th Multidimensional Chromatography Workshop in Liege, Belgium, all the way from Los Angeles (true story). Amid a longer layover, I decided to give ChatGPT a try. The initial requirement was to complete registration, and that's precisely where my journey took a pause. Tired of repeatedly entering my information and fabricating fake email addresses, I often encountered rapid responses like, "This email address ([email protected]) does not exist." Their efficiency left me intrigued. This marked my initial, almost comical first encounter with ChatGPT.

Following an enjoyable conference experience, I made my way back, engaging with my students and prompting them to embark on a paper-writing endeavor. Our starting point was the creation of a paper outline. Concluding the meeting, I strolled to my office (a 90-second walk), receiving a text from my students along the way:

The LCGC Blog: Are You Sick of Hearing About ChatGPT - text messages (Petr Vozka, 2023)

In no time, the outline landed in my inbox. And at that point, I finished the registration and started exploring ChatGPT's capabilities. And if you're wondering why, simply see below: the ChatGPT-generated outline (achieved in under 90 seconds) with the outline I had envisioned (added parts are marked in italics and omitted parts with <u> underlines</u> ).

The LCGC Blog: Are You Sick of Hearing About ChatGPT - prompt 1 (Petr Vozka, 2023)

I. Introduction

A. Brief overview of the importance of olefin quantification in <u>gas chromatography</u> fuels made from plastic waste

B. Introduction of two dimensional gas chromatography (GCXGC) and flame ionization detector (FID)

II. Method Development

A. Selection of column dimensions and stationary phases

B. Optimization of GCXGC parameters such as modulation time and flow rate

C. Determination of optimum temperature programs for each column

E. Development of calibration standards using olefinic compounds and saturated hydrocarbons

F. Comparison of FID response factors for olefins and saturated hydrocarbons

G. Derivatization techniques for improving olefin detection and quantification

H. Normalization of chromatograms and calculations

III. Results and Discussion

A. Evaluation of the developed method for olefin detection and quantification

B. Comparison of the developed method with existing <u>GC methods</u> ASTM-approved methods

C. Discussion of the advantages and limitations of the developed method

D. GCxGC method linearity

IV. Conclusion

A. Summary of the key findings of the study

B. <u>Implications of the developed method for olefin quantification in various industries</u>

C. Future directions for further improvements of the developed method.

So, that isn't bad, is it? It's important to note that ChatGPT may not always provide accurate or reliable information, and its responses are based on patterns it learned from its training data. It can sometimes generate plausible-sounding yet incorrect or nonsensical answers, so critical thinking is advised when using its outputs. This aspect becomes particularly evident when ChatGPT is prompt to provide reference suggestions, as the references it generates are mostly made up but sound plausible due to ChatGPT's lack of direct access to external databases.

The LCGC Blog: Are You Sick of Hearing About ChatGPT - prompt 2 (Petr Vozka, 2023)

Here are a few examples generated by ChatGPT:

(1) Marriott, P. J., & Shellie, R. (2002). Comprehensive two-dimensional gas chromatography–a review. Journal of Chromatography A, 965(1-2), 175-195.

(2) Phillips, J. B., Harada, R. M., & Reichenbacher, K. (2011). Performance of a two-dimensional gas chromatography system with a nonpolar–polar column combination for the separation of compounds in gasoline and diesel fuels. Journal of Chromatography A, 1218(28), 4391-4397.

Unfortunately, these publications do not exist; however, if they were, we would definitely want to include them in our manuscript.

In a similar manner, ChatGPT can assist you in preparing the structure for the Introduction. Another useful tool is to ask ChatGPT to condense your Abstract if you need to meet a word count requirement. If the Abstract generated by ChatGPT turns out to be too short or long, you can continue with the instructions and direct ChatGPT to extend or shorten it. Alternatively, if you find yourself pressed for time and unable to read an entire paper, you can request ChatGPT to provide a summary of the results for you.

Since English is not my native language, I often use ChatGPT to check my grammar and even to rewrite, polish, or paraphrase certain paragraphs. For example, each paragraph presented here has been reviewed by ChatGPT. (Here is a helpful tip: copy and paste each paragraph individually before proceeding to the next one.) You might even move this one step forward and generate a paragraph.

The LCGC Blog: Are You Sick of Hearing About ChatGPT - prompt 3 (Petr Vozka, 2023)

“Using ChatGPT responsibly within academia involves a balanced approach that harnesses its advantages while upholding scholarly principles. Remember, ChatGPT is a tool, not a replacement for critical thinking or original research. To optimize its utility, define the specific aid you need, whether refining language or idea generation. Employ focused and evolving prompts to elicit accurate responses, cross-referencing its suggestions with reliable sources and experts to ensure credibility. While ChatGPT enhances your work, avoid overdependence by using it as a supplementary resource rather than a primary creator. Uphold ethical standards by transparently acknowledging ChatGPT's contributions in your work. By adhering to these practices, a symbiotic relationship between AI technology and academia can be nurtured, fostering responsible and effective integration.” – ChatGPT, 2023

No, there's no need to say "please." I just prefer to be polite, just in case ChatGPT becomes Skynet from “The Terminator” movies one day.

You might come across a rumor suggesting that ChatGPT can answer questions from MIT exams, leading to the assertion that AI could potentially earn a university degree from such esteemed institutions. This was later refuted by several studies, with the conclusion that ChatGPT is indeed not capable of obtaining a degree from MIT. However, ChatGPT can answer simpler questions in a very efficient way. During the COVID-19 pandemic, many universities switched to remote teaching, which included remote student exams. Since students were capable of consistently finding methods to search for answers online despite the exams not being open-book format, one solution was to implement essay-type or true/false questions. However, these are no longer viable options, as ChatGPT can solve these general questions without the need for students to gather information from several sources and writing the summary in their own words (see below).

The LCGC Blog: Are You Sick of Hearing About ChatGPT - exam answer 1 (Petr Vozka, 2023)

The LCGC Blog: Are You Sick of Hearing About ChatGPT - exam answer 2 (Petr Vozka, 2023)

An example of an essay-type question to support my argument could be: "Briefly describe how a TOF mass analyzer works, based on the relationship between flight time (t), mass-to-charge ratio (m/z), and electric field (E)." I haven't included the answer here, but you can give it a try yourself. As more and more students are using ChatGPT, professors will have to adapt as well.

So, what is the conclusion if there is one at all? Up until now, ChatGPT has remained ad-free and freely accessible, a rarity in my view. So, why not take advantage of it? Just keep in mind that ChatGPT is "only" proficient in a diverse array of natural language processing tasks, encompassing but not limited to: generating text (offering coherent and contextually relevant content based on given prompts, thus facilitating the creation of articles, blogs, poems, and more), completing text (forming sentences or paragraphs, serving as a valuable tool for brainstorming, writing prompts, and content generation), summarizing text (concisely condensing lengthy passages while retaining essential information), translating languages, extracting data (retrieving structured data from unstructured text), and much more.

Petr Vozka: Petr Vozka, Assistant Professor na California State University, Los Angeles

About the Author: Petr Vozka (Complex Chemical Composition Analysis Lab (C³AL)

Petr Vozka is an assistant professor of analytical chemistry in the Department of Chemistry and Biochemistry at the California State University, Los Angeles, USA. He is also the director of the Complex Chemical Composition Analysis Lab (C3AL). His research focuses on characterizing complex chemical mixtures using state-of-the-art techniques, such as two-dimensional gas chromatography (GC×GC) and high‑resolution mass spectrometry (HRMS). His primary focus is on developing methods for analyzing products from plastic waste conversion processes and organic compounds adsorbed on microplastics. He has one patent, six military reports, 25 journal publications, and over 30 research presentations, which include 10 invited lectures and invited presentations. He was invited as a keynote speaker to the 14th Multidimensional Chromatography Workshop in 2023.

LCGC
 

Related content

Simultaneous Analysis of Residual Pesticides Using High-Speed Scan and Smart SIM+ of GCMS-QP2050

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Food & Agriculture

Agilent 8850 GC system

Brochures and specifications
| 2024 | Agilent Technologies
Instrumentation
GC
Manufacturer
Agilent Technologies
Industries
Others

GC/GC-MS Glass Insert/Liner Selection Guide

Guides
| 2024 | Shimadzu
Instrumentation
Consumables, GC, GC/MSD
Manufacturer
Shimadzu
Industries
Others

Improving Battery Production Yield, Performance, and Stability Using FTIR

Applications
| 2024 | Agilent Technologies
Instrumentation
FTIR Spectroscopy
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals , Materials Testing

An advanced integrated GC-MS/MS and LC-MS/MS workflow for the comprehensive analysis of pesticide residues in food

Applications
| 2024 | Thermo Fisher Scientific
Instrumentation
GC/MSD, GC/MS/MS, GC/QQQ, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Food & Agriculture
 

Related articles


Article | Upcoming events

Cal State LA hosts 15th Multidimensional Chromatography Workshop

This January, Cal State LA became a hub for scientists and researchers as it hosted the 15th Multidimensional Chromatography Workshop.
Complex Chemical Composition Analysis Lab (C³AL)
more

Article | Video

Scientists from IOCB Prague are expanding the possibilities of using RNA in gene medicine

Dr Petr Cígler and his collaborators are working on refining molecular systems for transporting ribonucleic acid (RNA) molecules into cells.
Ústav organické chemie a biochemie AV ČR
more

Article | Video

New approach enhances muscle recovery in aged mice

Scientists have developed a promising new method to combat the age-related losses in muscle mass that often accompany immobility after injury or illness.
University of Illinois Urbana-Champaign
more

Article | Scientists

Gerrit Angst awarded the Lumina quaeruntur premium. He will start a new research team

Soil biologist Gerrit Angst from the Biology Centre of the CAS received the prestigious Lumina quaeruntur Premium from the President of the Czech Academy of Sciences.
Akademie věd České republiky
more
 

Related content

Simultaneous Analysis of Residual Pesticides Using High-Speed Scan and Smart SIM+ of GCMS-QP2050

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Food & Agriculture

Agilent 8850 GC system

Brochures and specifications
| 2024 | Agilent Technologies
Instrumentation
GC
Manufacturer
Agilent Technologies
Industries
Others

GC/GC-MS Glass Insert/Liner Selection Guide

Guides
| 2024 | Shimadzu
Instrumentation
Consumables, GC, GC/MSD
Manufacturer
Shimadzu
Industries
Others

Improving Battery Production Yield, Performance, and Stability Using FTIR

Applications
| 2024 | Agilent Technologies
Instrumentation
FTIR Spectroscopy
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals , Materials Testing

An advanced integrated GC-MS/MS and LC-MS/MS workflow for the comprehensive analysis of pesticide residues in food

Applications
| 2024 | Thermo Fisher Scientific
Instrumentation
GC/MSD, GC/MS/MS, GC/QQQ, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Food & Agriculture
 

Related articles


Article | Upcoming events

Cal State LA hosts 15th Multidimensional Chromatography Workshop

This January, Cal State LA became a hub for scientists and researchers as it hosted the 15th Multidimensional Chromatography Workshop.
Complex Chemical Composition Analysis Lab (C³AL)
more

Article | Video

Scientists from IOCB Prague are expanding the possibilities of using RNA in gene medicine

Dr Petr Cígler and his collaborators are working on refining molecular systems for transporting ribonucleic acid (RNA) molecules into cells.
Ústav organické chemie a biochemie AV ČR
more

Article | Video

New approach enhances muscle recovery in aged mice

Scientists have developed a promising new method to combat the age-related losses in muscle mass that often accompany immobility after injury or illness.
University of Illinois Urbana-Champaign
more

Article | Scientists

Gerrit Angst awarded the Lumina quaeruntur premium. He will start a new research team

Soil biologist Gerrit Angst from the Biology Centre of the CAS received the prestigious Lumina quaeruntur Premium from the President of the Czech Academy of Sciences.
Akademie věd České republiky
more
 

Related content

Simultaneous Analysis of Residual Pesticides Using High-Speed Scan and Smart SIM+ of GCMS-QP2050

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Food & Agriculture

Agilent 8850 GC system

Brochures and specifications
| 2024 | Agilent Technologies
Instrumentation
GC
Manufacturer
Agilent Technologies
Industries
Others

GC/GC-MS Glass Insert/Liner Selection Guide

Guides
| 2024 | Shimadzu
Instrumentation
Consumables, GC, GC/MSD
Manufacturer
Shimadzu
Industries
Others

Improving Battery Production Yield, Performance, and Stability Using FTIR

Applications
| 2024 | Agilent Technologies
Instrumentation
FTIR Spectroscopy
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals , Materials Testing

An advanced integrated GC-MS/MS and LC-MS/MS workflow for the comprehensive analysis of pesticide residues in food

Applications
| 2024 | Thermo Fisher Scientific
Instrumentation
GC/MSD, GC/MS/MS, GC/QQQ, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Food & Agriculture
 

Related articles


Article | Upcoming events

Cal State LA hosts 15th Multidimensional Chromatography Workshop

This January, Cal State LA became a hub for scientists and researchers as it hosted the 15th Multidimensional Chromatography Workshop.
Complex Chemical Composition Analysis Lab (C³AL)
more

Article | Video

Scientists from IOCB Prague are expanding the possibilities of using RNA in gene medicine

Dr Petr Cígler and his collaborators are working on refining molecular systems for transporting ribonucleic acid (RNA) molecules into cells.
Ústav organické chemie a biochemie AV ČR
more

Article | Video

New approach enhances muscle recovery in aged mice

Scientists have developed a promising new method to combat the age-related losses in muscle mass that often accompany immobility after injury or illness.
University of Illinois Urbana-Champaign
more

Article | Scientists

Gerrit Angst awarded the Lumina quaeruntur premium. He will start a new research team

Soil biologist Gerrit Angst from the Biology Centre of the CAS received the prestigious Lumina quaeruntur Premium from the President of the Czech Academy of Sciences.
Akademie věd České republiky
more
 

Related content

Simultaneous Analysis of Residual Pesticides Using High-Speed Scan and Smart SIM+ of GCMS-QP2050

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Food & Agriculture

Agilent 8850 GC system

Brochures and specifications
| 2024 | Agilent Technologies
Instrumentation
GC
Manufacturer
Agilent Technologies
Industries
Others

GC/GC-MS Glass Insert/Liner Selection Guide

Guides
| 2024 | Shimadzu
Instrumentation
Consumables, GC, GC/MSD
Manufacturer
Shimadzu
Industries
Others

Improving Battery Production Yield, Performance, and Stability Using FTIR

Applications
| 2024 | Agilent Technologies
Instrumentation
FTIR Spectroscopy
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals , Materials Testing

An advanced integrated GC-MS/MS and LC-MS/MS workflow for the comprehensive analysis of pesticide residues in food

Applications
| 2024 | Thermo Fisher Scientific
Instrumentation
GC/MSD, GC/MS/MS, GC/QQQ, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Food & Agriculture
 

Related articles


Article | Upcoming events

Cal State LA hosts 15th Multidimensional Chromatography Workshop

This January, Cal State LA became a hub for scientists and researchers as it hosted the 15th Multidimensional Chromatography Workshop.
Complex Chemical Composition Analysis Lab (C³AL)
more

Article | Video

Scientists from IOCB Prague are expanding the possibilities of using RNA in gene medicine

Dr Petr Cígler and his collaborators are working on refining molecular systems for transporting ribonucleic acid (RNA) molecules into cells.
Ústav organické chemie a biochemie AV ČR
more

Article | Video

New approach enhances muscle recovery in aged mice

Scientists have developed a promising new method to combat the age-related losses in muscle mass that often accompany immobility after injury or illness.
University of Illinois Urbana-Champaign
more

Article | Scientists

Gerrit Angst awarded the Lumina quaeruntur premium. He will start a new research team

Soil biologist Gerrit Angst from the Biology Centre of the CAS received the prestigious Lumina quaeruntur Premium from the President of the Czech Academy of Sciences.
Akademie věd České republiky
more
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike