EU Regulation 396/2005: Pesticide Residue Testing and the Critical Role of QuEChERS Evaporation in Food Safety

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 4th May 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you application note by Shimadzu, presentation by MDCW / JEOL and technical note by Thermo Fisher Scientific!<h3>1. MDCW / JEOL: Flow-Modulated GCxGC-QMS Analysis Without Splitting Off the GC Flow</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_16_Jensen_11e29d5022.pdf">Full PDF for download</a></li></ul><section><div><div><div><div><div><div>This presentation by Kirk Jensen (JEOL USA) explores the feasibility of performing flow-modulated comprehensive two-dimensional gas chromatography (GC×GC) coupled with quadrupole mass spectrometry (QMS) without splitting the GC flow, which is traditionally required to protect MS systems from high carrier gas flows. The core concept builds on GC×GC, where compounds are separated using a primary and secondary column connected via a modulator, significantly increasing separation power compared to one-dimensional GC. The presentation contrasts thermal modulation (offering sharper peaks and higher theoretical sensitivity but requiring cryogenic cooling) with flow modulation, which avoids cryogens, handles volatile analytes well, and is more flexible, but typically demands higher gas flows that standard MS systems cannot tolerate .To address this limitation, the study utilizes the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=24&amp;search=JMS-Q1600GC">JEOL JMS-Q1600GC</a> UltraQuad quadrupole GC-MS system, which can accept unusually high carrier gas flows (up to ~20 mL/min), enabling direct coupling with a SepSolve INSIGHT flow modulator without splitting the effluent . The analytical setup includes dual GC columns (e.g., Zebron ZB-5MSplus for the first dimension and BPX50 for the second), high secondary flow rates (~25 mL/min), and electron ionization (EI) MS detection. Additional system components include optional FID detection, bleed line control, and ChromeSpace software for data processing . This configuration allows full analyte transfer into the MS, eliminating the need for flow splitting and potentially improving detection efficiency.Experimental results demonstrate the applicability of this approach to complex mixtures, including a pesticide mixture containing over 200 compounds and real-world samples such as perfumes and fuels. The GC×GC-MS system produced detailed two-dimensional chromatograms with high spectral quality, enabling the correct identification of approximately 120 compounds despite relatively moderate spectral match factors . Comparisons at different flow rates (e.g., 25 vs. 50 mL/min) showed that spectral integrity and compound identification remain robust, indicating that higher flow operation does not significantly compromise MS performance.In conclusion, the work demonstrates that flow-modulated GC×GC-QMS without flow splitting is feasible, provided that the MS system can tolerate high carrier gas flows. While further optimization is needed (e.g., column selection, inlet pressure, and separation conditions), the approach offers a practical alternative to thermal modulation by eliminating cryogens and simplifying operation. Future work will focus on improving sensitivity, optimizing separations, and exploring alternative carrier gases such as hydrogen to reduce costs and expand applicability</div></div></div></div></div></div></section><h3>2. Shimadzu: Detailed Hydrocarbon Analysis by Nexis GC-2030 Using ASTM D6730</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00863_en_eb633bc741.pdf">Full PDF for download</a></li></ul><h5>User Benefits</h5><ul><li>Detailed compositional analysis of gasoline in accordance with ASTM D6730 is feasible using the Nexis GC-2030.&nbsp;</li><li>By employing PONAsolution, a PONA/DHA analysis software, laborious identification tasks can be reduced, and quantitation calculations and report generation can be performed automatically.</li></ul>ASTM D6730 specifies the analysis of hydrocarbons in gasoline and oxygenates such as ethanol, methyl tert-butyl ether (MTBE), and ethyl tert-butyl ether (ETBE) over a boiling point range up to 225 ̊C. Identification and quantification of individual compounds in gasoline are critically important for refinery process control and product quality assurance. In this application news, we report compositional analysis of gasoline conforming to ASTM D6730 using the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Nexis+GC-2030">Nexis GC-2030 gas chromatograph</a>. Gasoline typically comprises over 100 hydrocarbons, making identification tasks highly complex; however, PONAsolution, a PONA/DHA analysissoftware,simplifies this process.<h4>PONAsolution</h4>PONAsolution Ver.6 provides retention index libraries for each relevant standard (ASTM D6730, D6729, D5134, D6733). Identification of n-alkanes automatically corrects the retention times of the remaining several hundred components, thus streamlining the identification process. When only a specific retention region requires adjustment, the two-point identification function is useful (Fig. 1). In the two-point identification procedure, reference and sample chromatograms are compared while assigning corresponding peaks. First, click on an identified component mark in the reference data (Fig. 1, a), then click the matching sample peak (Fig. 1, b). Repeat this for a second pair of peaks. The retention times of components between these two anchor points are then automatically corrected.<h4>Conclusion</h4>Compositional analysis of gasoline in accordance with ASTM D6730 was performed. The combination of SH PONA Tuning Column and SH-1 PONA main column enabled separation of compounds with closely spaced retention times. Moreover, use of PONAsolution software greatly simplifies complex identification tasks.<h3>3. Thermo Fisher Scientific: Fiber optic probes add flexibility to Raman chemical analysis</h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/drx3_flex_tech_note_tn54708_bebb56b870.pdf">Full PDF for download</a></li></ul>Fourier Transform Infrared Spectroscopy (FTIR) and Raman Spectroscopy are non-destructive analytical techniques that rely on the interaction of electromagnetic radiation with molecular vibrations to provide information about the chemical composition and structure of a sample. Despite their similarities, there are some distinct differences between the two techniques. In principle, FTIR is based on the absorption of infrared radiation by molecules and measures changes in dipole moment during molecular vibrations. Raman spectroscopy, on the other hand, is based on the inelastic scattering of monochromatic light and measures changes in polarizability during molecular vibrations.&nbsp;When applied to bulk chemical analysis, both FTIR and Raman spectroscopy can be used to analyze solids, liquids, and gases, but the nature of Raman spectroscopy lends some unique sampling advantages. Additionally, Raman often requires little to no sample preparation. Presented herein are application examples that highlight some of the sampling advantages of Raman spectroscopy. All the spectral data in this technical note were collected using a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2238">Thermo Scientific™ DXR3 Flex Raman Spectrometer</a> equipped with a fiber optic probe. (Fiber optics are readily available for Raman spectroscopy because of the use of visible and NIR light and do not require the exotic materials associated with FTIR fiber optics.) Preliminary tests for all samples were carried out using both 532 nm and 785 nm excitations, and it was determined that the 785 nm laser set gave an overall better balance between fluorescence and Raman scattering efficiency.<h4>Summary&nbsp;</h4>In this technical note, the analyses of a variety of samples by Raman spectroscopy are demonstrated. All samples were analyzed without sample preparation.&nbsp;<ul><li>Precise and localized analysis at the focal point of the Raman-exciting laser allows sampling through glass bottles, blister packaging and plastic containers, which eliminates possible cross contamination and analyst exposure to hazardous materials. The contributions from the packaging and containers depend on the type of container material, the container thickness, and the materials’ chemical compositional complexity, but these contributions can be readily subtracted out when needed.&nbsp;</li><li>Water is a weak Raman scatterer. Raman therefore has reduced water sensitivity, making it a preferred technique for aqueous solution analysis over FTIR. As demonstrated in the analysis of an energy drink, the Raman bands from water can be subtracted from the spectrum of the aqueous solution, leading to the identification of the components of the solution.&nbsp;</li><li>Raman spectroscopy is well suited for the analysis of inorganic materials, especially in identifying the crystal phases and polymorphs, as demonstrated by the analyses of minerals and pigments in a painting.&nbsp;</li><li>Fiber optic probes provide flexibility and ease of maneuverability. This is particularly advantageous when analyzing samples that are difficult to access or manipulate, such as large containers, geological samples and paintings</li></ul>The DXR3 Flex has multiple sampling options available. A properly configured fiber-optic probe is arguably the most versatile accessory for the analysis of bulk solids and liquids. The advantages, both from those inherent to Raman spectroscopy and those resulting from the use of fiber optic probe, provide opportunities for a wide variety of different applications when using the DXR3 Flex Raman Spectrometer.

News from LabRulezGCMS Library - Week 19, 2026

🎤Francis Femi OloyIn this episode of Concentrating on Chromatography, David speaks with Francis Femi Oloy about using chromatography to uncover hidden pollutants in real-world water systems.Femi’s team analyzed polychlorinated biphenyls (PCBs) in six major rivers in southwestern Nigeria — compounds that were banned decades ago but still persist in the environment. Using a workflow that many analytical labs will recognize — liquid–liquid extraction, cleanup, rotary evaporation, nitrogen blowdown, and GC-ECD detection — they quantified 25 PCB congeners at trace levels and linked the results to ecological and human health risk.<h4>In this conversation, we cover:</h4><ul><li>Why legacy pollutants like PCBs still show up today</li><li>Choosing GC-ECD vs LC-MS for halogenated compounds</li><li>Liquid–liquid extraction and matrix cleanup strategies</li><li>Why sample concentration is critical for dilute environmental samples</li><li>How rotovap + nitrogen blowdown work together without losing volatile analytes</li><li>Seasonal trends (why wet season levels were higher)</li><li>Translating concentration data into meaningful risk assessments</li></ul><h3>Video Transcription</h3><section><div><div><div><div><div><div>Persistent organic pollutants such as polychlorinated biphenyls (PCBs) remain a significant environmental concern despite decades of regulatory restrictions. In this interview, Francais Femi Oloy discusses the environmental and analytical challenges associated with monitoring PCB contamination in rivers of southwestern Nigeria, a rapidly industrializing region where urban growth, industrial activity, agriculture, and dense populations intersect with extensive aquatic systems.Oloy explains that his interest in environmental contaminant analysis emerged from observing unexplained health problems and environmental degradation while growing up in Nigeria. This motivated his transition into organic and environmental chemistry, with a focus on identifying pollutants present in drinking water, agricultural soils, and food systems. Southwestern Nigeria, particularly the Lagos region, represents a critical environmental monitoring area due to intense industrial development, shipping activity, and widespread human dependence on rivers for domestic use, agriculture, and fishing.Although PCBs are considered “legacy pollutants” and are no longer intentionally produced, the interview highlights why they continue to persist in aquatic environments. Old electrical transformers and aging industrial equipment still contain PCB residues, while historical contamination stored in river sediments can become remobilized during flooding, dredging, or sediment disturbance. Because PCBs are hydrophobic and resistant to degradation, they preferentially accumulate in sediments and bioaccumulate through aquatic food chains, creating long-term environmental and human exposure risks.A major focus of the discussion centers on the analytical workflow used for PCB determination in environmental water samples. Composite river water samples were collected in amber glass bottles to avoid contamination and photodegradation, preserved with sodium azide to minimize microbial activity, and stored under cooled conditions prior to extraction. The analytical protocol employed liquid–liquid extraction using dichloromethane (DCM) and hexane to recover both polar and nonpolar PCB congeners. Oloy emphasizes that liquid–liquid extraction was selected over solid-phase extraction (SPE) because of concerns about congener retention within sorbent materials and clogging issues associated with large-volume environmental samples.Following extraction, concentration and cleanup represented critical analytical stages due to the trace-level occurrence and volatility of PCBs. Silica and alumina cleanup procedures were used to remove matrix interferences prior to instrumental analysis. The concentration workflow combined rotary evaporation for bulk solvent reduction with nitrogen blowdown for final volume reduction to less than 1 mL, while carefully avoiding excessive temperature or complete dryness to minimize analyte loss. Oloy repeatedly stresses that improper concentration procedures are among the most common causes of analytical failure in PCB analysis.For instrumental determination, the study utilized gas chromatography coupled with electron capture detection (GC-ECD) rather than LC-MS or GC-MS. According to Oloy, GC was preferred because PCBs are sufficiently volatile for gas chromatographic separation, while ECD provided superior sensitivity and selectivity for chlorinated compounds at environmentally relevant concentrations. The interview also discusses analytical validation strategies, including the use of surrogate standards to assess recoveries, which ranged from approximately 85% to 114%, and signal-to-noise-based determination of detection limits.The study further examined seasonal variations in PCB concentrations, revealing higher levels during the wet season. This observation was attributed to rainfall-driven runoff from contaminated infrastructure, sediment resuspension, and lower temperatures that reduce volatilization losses. To communicate toxicological relevance beyond simple concentration reporting, the researchers also calculated toxic equivalency values (TEQs), converting mixtures of PCB congeners into biologically meaningful toxicity estimates comparable to dioxin toxicity metrics.Beyond environmental monitoring, Oloy highlights broader research interests focused on pollutant remediation and sustainable environmental protection. His group is also involved in developing catalytic materials capable of degrading or removing persistent contaminants from environmental systems. Throughout the discussion, he emphasizes that analytical chemistry plays a central role not only in detecting pollutants, but also in enabling prevention, remediation, and long-term environmental management strategies.</div></div></div></div></div></div></section><blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Tracking Toxic PCBs in River Water using Gas Chromatography–Electron Capture Detection

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Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

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Agilent Technologies

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SelectScience

Headspace sampling is a simple and elegant method for volatile organic compound (VOC) extraction, which has been successfully used to detect and quantify biomarkers for respiratory disease and liver impairment.
Learn about an optimized method for the detection of key analytes such as aldehydes, alkanes and ketones from culture media samples. The method combines high-capacity sorptive extraction technology with automated thermal desorption (TD), coupled with gas chromatography (GC) separation and mass spectrometry (MS) analysis, to provide reliable detection below 1 ng and high-throughput analysis of samples.
This webinar will showcase how Owlstone Medical, in collaboration with Markes, has developed headspace analytical methods for the detection of volatile biomarkers, putting us much closer to breath-based diagnostics for lung disease and liver impairment.
<h3>By attending this webinar, you will:</h3>
<ul>
<li>Learn about HiSorb™ for the extraction and analysis of volatile and semi-volatile organic compounds as indicators of disease and organ impairment</li>
<li>See how the Centri® platform can fully automate sample extraction &amp; desorption, improving laboratory productivity and analytical sensitivity.</li>
<li>Understand how analyte preconcentration, using cryogen-free trapping technology, can be optimized for low-level compounds of interest in complex sample types</li>
<li>Hear how the technique helped to overcome complex challenges, enabling the discovery of biomarkers to advance breath-based diagnostics</li>
</ul>
<h3>Who should attend?</h3>
<ul>
<li>Laboratories thinking of extending their sample extraction and analysis portfolio to answer growing business and research demands</li>
<li>Scientists interested in simplifying and expediting the analysis of complex samples, whether for discovery and development or routine monitoring and quality control</li>
<li>Environmental, flavor, scents, toxicology and diagnostics scientists</li>
<li>Laboratory managers/directors/supervisors interested in how advanced analytical techniques can provide a competitive edge and expand capabilities</li>
</ul>
<h3>Certificate of attendance</h3>
<ul>
<li>All webinar participants can request a certificate of attendance, including a learning outcomes summary for continuing education purposes.</li>
</ul>
<blockquote>
Presenter: Dr. Alexandra Martin (Analytical research &amp; Development Scientist, Owlstone Medical Ltd)
</blockquote>
<blockquote>
Following her MSci in natural sciences at the University of Birmingham, Alexandra also completed her Ph.D. in biophysical chemistry at the University of Birmingham in 2020, researching the physicochemical differences between mammalian and bacterial model cell membranes. She joined Owlstone in 2020 as an applications scientist and now works in breath biopsy test projects aiming to diagnose early-stage lung cancer and other diseases using breath sampling, with a focus on headspace GC-MS techniques.
</blockquote>
<blockquote>
Presenter: Rachael Szafnauer (Applications Scientist, Markes International Ltd)
</blockquote>
<blockquote>
Rachael Szafnauer received an MSci in forensic science from the University of South Wales, UK, where her final-year project focused on fingerprinting emerging psychoactive substances using advanced techniques such as GCxGC–TOF MS, in collaboration with Markes International. She later took up the role of thermal desorption product specialist at Markes, providing technical and application support to the commercial team, before taking on her current role as product marketing manager for the Centri product line and specializing in the development of applications using extraction and enrichment techniques for GC-MS.
</blockquote>
<blockquote>
Presenter: Sarah Thomas (Selectscience)
</blockquote>
<blockquote>
Sarah studied biology at the University of Bath, UK, and has worked in the Pharmaceutical Sciences Department of St. Jude Children’s Research Hospital, Memphis. As a member of the Editorial team, Sarah plays an integral role in shaping the content on SelectScience.
</blockquote>

Unsplash/Brett Jordan: Detect, discover, diagnose: Uncovering biomarkers to advance non-invasive breath-based diagnostics

Detect, discover, diagnose: Uncovering biomarkers to advance non-invasive breath-based diagnostics

Agilent and GERSTEL are happy to host this 4-day live virtual seminar discussing how you can assure safety, authenticity, and quality of alcoholic beverages. The focus will be on sharing the latest in technology developments and capabilities, new applications, and customer stories. Topics include spirits, wine, beer, and cider. There is something for everyone in this seminar series and we are glad to see you here.
<h3>Presentation 1: Undergraduate Research in the Fermentation Science of Aroma Using HS-SPME-GC-MS</h3>
<ul>
<li>Presenter: Dr. Callie Cole (Associate Professor of Chemistry, Fort Lewis College)</li>
</ul>
Headspace Solid Phase Microextraction Gas Chromatography Mass Spectrometry (HS-SPME-GC-MS) Analysis has been previously employed as an efficient and robust method for the detection of trace analytes in a wide variety of foods and beverages. However, the many variables that influence the volatile organic compounds (VOCs) released by hopped cider and beer remain to be studied in detail. Undergraduate research students at Fort Lewis College have collaborated with local cideries and breweries in Montezuma County and La Plata County Colorado to prepare hopped ciders and beers controlling for important fermentation variables to better understand their impact on final beverage quality.
<h5>Key Learning Objectives/What attendees will learn:</h5>
<ul>
<li>An instrumental analysis project that is manageable in an undergraduate research laboratory</li>
<li>What VOCs are produced by hopped beverages and how to measure them by HC-SPME-GC-MS</li>
<li>Practical take-aways for hopped beer and cider producers to improve aroma quality</li>
</ul>
<h5>Who Should Attend:</h5>
Those interested in undergraduate research and hopped beverage analysis
<h3>Presentation 2: Evaluating New England IPAs using TF-SPME-GC-MS</h3>
<ul>
<li>Presenter: Scott Frost (Postdoctoral Fellow, Tufts University)</li>
</ul>
New England IPAs are one of the most popular styles of craft beers. This hop-centric beer is commonly brewed with a large quantity of Citra and/or Mosaic hops, which produces the characteristic tropical and citrus fruit aromas. Thin film-solid phase microextraction (TF-SPME) in conjunction with gas chromatography mass spectrometry is an excellent tool to evaluate the volatile profile of this unique beer style.
<h5>Key Learning Objectives/What attendees will learn:</h5>
<ul>
<li>Application of TF-SPME for beer analysis.</li>
<li>Evaluation of: PDMS-twister; TF-SPMS DVB/PDMS; PDMS-twister + TF-SPMS DVB/PDMS</li>
</ul>
<h5>Who Should Attend:</h5>
Beer professionals, beer chemists, anyone who like GC/MS and beer
<blockquote>
Presenter: Callie Cole, PhD (Assistant Professor, Fort Lewis College)
</blockquote>
<blockquote>
Dr. Cole is an assistant professor of Chemistry at Fort Lewis College: a small, rural, primarily undergraduate institution (PUI) in Durango, CO. She joined the college in 2015 and teaches undergraduate courses in first year programs, general chemistry, analytical chemistry, instrumental analysis, and senior research. In spring 2015, Dr. Cole received her Ph.D. in Analytical Chemistry as a National Science Foundation Graduate Research Fellow from the University of Colorado at Boulder. She was recently honored to receive the 2019-2020 American Society for Mass Spectrometry (ASMS) Research at PUIs Award from Agilent Technologies as well as the 2019-2020 Undergraduate Analytical Research Program (UARP) Award from the Society of Analytical Chemists of Pittsburg (SACP) to support her and her undergraduate student’s research at Fort Lewis College. Dr. Cole&#39;s research centers around mass spectrometry and includes the analysis of volatile compounds responsible for the aroma and taste of locally-produced ciders, the quantification of metals in environmental samples (soil and plant), as well as the reactivity and fragmentation of astrophysically-relevant ions.
</blockquote>
<blockquote>
Dr. Cole&#39;s work has recently been published in Beverages, The Astrophysical Journal, Journal of the American Chemical Society, and the Journal of Physical Chemistry A. Her recent conference presentations include the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, Chicago, IL (2020), the American Society for Mass Spectrometry National Meeting, Atlanta, GA (2019), the American Chemical Society National Meeting, New Orleans, Louisiana (2018), the Geological Society of America National Meeting, Denver, CO (2016), and the Astrochemistry of Dust, Ice, and Gas Faraday Discussion, Leiden, The Netherlands (2014).
</blockquote>
<blockquote>
Presenter: Scott Frost (Postdoctoral Fellow, Tufts University
</blockquote>
<blockquote>
Scott Frost is a sensory scientist and flavor chemist with Tufts University. His research explores how production practices influence consumer choice. After receiving his Master of Science from UC Davis, Scott ran a winery lab in California. This experience sparked his desire to understand how wine production can influence flavor chemistry. Since completing his Ph.D. he has worked on various food and beverages including wine, coffee, cheese, and beer.
</blockquote>

Agilent Technologies: Alcoholic Beverages Virtual Seminar

Alcoholic Beverages Virtual Seminar - Beer and Cider

2 Presentation: Undergraduate Research in the Fermentation Science of Aroma Using HS-SPME-GC-MS & Evaluating New England IPAs using TF-SPME-GC-MS.

The analysis of ETOX and 2-CE in various food products is important to guarantee food safety and meet international regulatory requirements; this is extremely challenging mainly due to the accumulation of high amounts of nonvolatile material in the liner, column and possible interference with Acetaldehyde.
Join this webinar to learn and master how you can develop and implement a robust and automated GC-MS/MS based method in your lab.
<h3>Topics</h3>
<ul>
<li>Ethylene oxide in food commodities- Regulations and Testing Requirements</li>
<li>Overcome challenges of ETOX analysis using the most advanced GC-MS/MS system</li>
<li>Fully automated cryogen-free analysis of ethylene oxide and 2-chloroethanol in foods using extraction &amp; multi-step enrichment (MSE®) techniques</li>
</ul>
<blockquote>
Presenter: Dr. Kaushik Banerjee (Principal Scientist, National Reference Laboratory, ICAR-National Research Centre for Grapes)
</blockquote>
<blockquote>
Dr Kaushik Banerjee is a Principal Scientist from the ICAR-National Research Centre for Grapes, Pune, India. He is a recipient of Fellow of the Indian National Academy of Agricultural Sciences (FNAAS) and Fellow of the Royal Society of Chemistry (FRSC), London. He is a member of the Scientific Panels of the Food Safety Standards Authority of India (FSSAI) on pesticide residues and methods of analysis.Dr Banerjee has widely published in peer-reviewed journals and offered numerous presentations at international meetings and conferences around the world.
</blockquote>
<blockquote>
Presenter: Praveen Arya (Product Specialist - GCMS, Agilent Technologies)
</blockquote>
<blockquote>
Praveen Arya, Application Engineer at Agilent technologies, has a commitment and appreciation for Gas-phase residue applications. In 2005, Mr. Praveen Arya completed his MSc. in Food Technology from CCS University, Meerut, Uttar Pradesh. After post-graduation, he served as a Senior Analyst at SGS, Gurgaon- a commercial testing laboratory for 6 years and developed expertise in Residue analysis using sophisticated chromatographic instruments such as LCMS and GCMS. After that, in 2011, He joined Agilent Technologies as an Application Engineer where he supported country-wide GCMS customers for resolving application issues and method development. He has more than 15 years of experience in residue analysis in food and environmental samples using various high end chromatographic and spectrometric techniques (GC, GCMS, GCMS/MS, TDS, Headspace, Purge &amp; trap etc.). His area of specialization includes new analytical method development and validation as per national and international guidelines.
</blockquote>
<blockquote>
Presenter: Rachael Szafnauer (Product Marketing Manager, Extraction &amp; Enrichment Products, Markes International)
</blockquote>
<blockquote>
Rachael Szafnauer received an M.Sci in forensic science from the University of South Wales, UK where her final-year project focused on fingerprinting emerging psychoactive substances using advanced techniques such as GCXGC-TOF MS, in collaboration with Markes International. She later took up the role of thermal desorption product specialist at Markes, providing technical and application support to the commercial team, before taking on her current role as Product Marketing Manager for Centri® product line and specialising in the development of applications using extraction &amp; enrichment techniques for GCMS.
</blockquote>

Agilent Technologies: Analysis of ETOX and 2-CE in various food products

Analysis of ETOX and 2-CE in various food products

Join Agilent and GERSTEL for our annual virtual seminar discussing how you can assure safety, authenticity, and quality of alcoholic beverages. Sharing the latest in technology developments and capabilities, new applications, and customer stories. Topics include distilled beverages, wine and beer. There is something for everyone in this seminar series and we hope to see you there.
Attend live and receive an Agilent GC wine glass!
<h3>Presentation 1: Non-targeted and Targeted Analysis of Spirits Aroma/Flavor Compounds using DHS-GC(-GC)-MS</h3>
Chromatographic analysis of distilled spirits has witnessed a sea change over a recent short period of years. Previous approaches which relied on solvent extraction procedures to enrich the secondary aroma/flavor compounds from the dominant ethanol-water base, can now be replaced by solventless, automated instrumental methods. Such solventless approaches comprise Stir Bar Sorptive Extraction, Static and Dynamic Headspace and Large Volume Injection. These methods rely on the ability of a PTV (Programmable Temperature Vaporization) injector to enrich analytes of interest before transfer to the GC column, while venting unwanted matrix.
Complex GC-MS data files obtained in this way, can also be further processed by powerful filters such as Spectral Deconvolution followed by RI based isolation and verification of identities of aroma/flavor compounds. The sequential progress of the GC-MS data file through these various filters and finally into a chemometric software for investigative discrimination of samples is achieved by simple mouse clicks. This is a very attractive outcome for practicing flavor Chemists and could be regarded as the final fulfillment of what previously could only be an outcome to aspire to.
These solventless techniques can be so efficient, and sometimes give such complex GC-MS data files, that often an additional chromatographic dimension may be required, especially for detection of ultra-trace compounds. This is supplied by chromatographic heart cutting where elution segments from one column are transferred to a second column of different polarity for increased resolution. The necessary instrumental configurations required for this purpose are also available in fully automated format.
Key Learning Objectives/What attendees will learn:
<ul>
<li>Appreciation of how analysis of distilled spirits has moved into a more modern approach using solventless extraction techniques featuring full automation from sample treatment to GC injection.</li>
<li>Aroma Office in conjunction with MS Spectral Deconvolution will be introduced as a powerful combination for filtering and listing of aroma compounds from complex GC-MS data files.</li>
<li>Two-dimensional Gas Chromatography (2D-GC-GC) will also feature as a valuable tool for isolation of key compounds from interfering matrix in extremely complex data files.</li>
</ul>
Who Should Attend: Chemists and Technicians involved in aroma research and analysis
<blockquote>
Presenter: Dr. Kevin Mac Namara (Consultant)
</blockquote>
<blockquote>
Dr Kevin Mac Namara graduated from the National University of Ireland with a speciality in synthetic organic chemistry. He later joined the Irish Government Alcohol Monopoly and subsequently moved to Irish Distillers Group in 1981 as Head of Technical Development where he established a high profile centre for distilled spirits research. When Irish Distillers merged into the global Pernod Ricard Group in 1990 he assumed a much enlarged role and represented Ireland in EU alcohol affairs for many years before retiring in 2012.
</blockquote>
<h3>Presentation 2: A Variety of Extraction Techniques Used to Determine Analytes of Interest in Distilled Spirits</h3>
Analysis of distilled spirits using GC-MS can be challenging due to the multitude of flavor and aroma compounds that exist in the predominantly ethanol-water mixture. The optimal extraction technique or techniques must be able to isolate and pre-concentrate the analytes before introduction into the GC-MS to produce meaningful data. GERSTEL offers numerous automated sample introduction and extraction techniques including Static Headspace (SHS), Solid Phase Microextraction (SPME), Thermal Desorption (TD), Dynamic Headspace (DHS), and Thin Film Solid-Phase Microextraction (TF-SPME) and Pyrolysis. GERSTEL offers additional features to each extraction technique including Multiple Headspace Sample Enrichment (MHSE) and TDx Multidesorption that can provide significantly more mass on column and lower detection limits. GERSTEL also offers unique detection capabilities with the olfactory detection port (ODP) allowing the analyst to smell compounds as they elute from the GC column. With simultaneous mass spectral detection, key odor-active compounds can be identified in complex products.
Common challenges encountered when analyzing distilled spirits include reproducibility of batches, identifying and quantifying off-odors produced during the fermentation process, and consumer satisfaction, especially in the context of competitors, to name a few. This presentation will show how GERSTEL addresses these complex challenges by having a complete “toolbox” of extraction, introduction and detection options that can be combined and optimized as needed.
Key Learning Objectives/What attendees will learn:
<ul>
<li>Theory and applicability of SHS, SPME, SBSE, TF-SPME, DHS, and pyrolysis.</li>
<li>How to decide on the most optimal extraction technique based on research challenges.</li>
</ul>
Who Should Attend: Analytical chemists in the food, flavor, fragrance, and beverage industries
<blockquote>
Presenter: Megan Harper (Applications Scientist l, GERSTEL, Inc.)
</blockquote>
<blockquote>
Megan Harper graduated from the University of Maryland Baltimore County in 2020 with a Bachelor of Science Degree in chemistry and received her Master of Science Degree in forensic science with an analytical chemistry track from Towson University in 2022. At GERSTEL, Inc., Harper applies her knowledge on sample extraction and introduction techniques to help solve complex problems for customers across the USA, including those involving distilled spirits.
</blockquote>

Pixabay/Bruno/Germany: 3rd Annual Alcoholic Beverages Virtual Symposium - Spirits

3rd Annual Alcoholic Beverages Virtual Symposium - Spirits

Non-targeted and Targeted Analysis of Spirits Aroma/Flavor Compounds using DHS-GC(-GC)-MS. Extraction Techniques Used to Determine Analytes of Interest

Non-alcoholic (NA) and low alcoholic beers (LABs) are growing in demand worldwide. However, dealcoholization or arrested fermentation leads to changes in the overall aroma and flavor profiles compared to full strength (FS) beer analogues.
This webinar Dr. Tiffany Crawford, Kalsec Inc., Megan Harper, GERSTEL, Inc., and Matt Curtis, Agilent will discuss a semi-targeted method developed using DHS-GC-MS technology that allows for the improvement of NA beer flavor through the addition of specialized hops products. They will also examine the use of GC-MS-O technology to determine the source of off-odors in a plant extract matrix. A brief overview of the GERSTEL dynamic headspace (DHS), Thermal Desorption Unit (TDU), and olfactory detection port (ODP) systems will be highlighted in order to understand their contributions to this work. The Agilent 7250 GC/QToF functionality will also be reviewed, along with the software tools e.g. SureMass feature-finding and MassProfiler Professional.
Key learning objectives
<ul>
<li>Understand the analytical challenges in the determination of off-flavors and off-odors in complex matrices
</li>
<li>Discover how a combination of GERSTEL and Agilent instrumentation and software can improve analysis for food and beverage applications
</li>
<li>Explore how analytical techniques can be used to identify and solve sensory issues in food products
</li>
</ul>
Who should attend?
<ul>
<li>Chemists and lab managers from contract testing labs and the food and beverage industry</li>
</ul>
<blockquote>
Presenter: Dr. Tiffany Crawford (Lead Scientist 1: Hops, Kalsec Inc.)
</blockquote>
<blockquote>
Dr. Tiffany Crawford works for Kalsec Inc. as a lead scientist in the hops business unit. In her role, she develops methods using GC-MS and LC-MS technology for the detection of small molecules of interest in different food matrices. She holds a Ph.D in Chemistry from the University of North Carolina at Chapel Hill.
</blockquote>
<blockquote>
Presenter: Megan Harper (Applications Scientist I, GERSTEL, Inc.)
</blockquote>
<blockquote>
Megan Harper works for GERSTEL, Inc. as an Applications Scientist. In her role, she applies her knowledge of GC-MS and sample extraction and introduction techniques to help solve complex problems for customers across the USA.
</blockquote>
<blockquote>
Presenter: Matt Curtis (GCMS Application Scientist, Agilent)
</blockquote>
<blockquote>
Matt Curtis joined Agilent in 2013 as a GC/MS applications scientist in the Santa Clara, CA Center of Excellence. His primary responsibility is providing instrument demonstrations for customer interested in each technology Agilent offers: the GC/MS single quadrupole, triple quadrupole and the quadrupole Time-of-Flight. The variety of different samples submitted to the demo lab provides a unique knowledge of optimizing parameters for different applications to provide the best quality data from the instrument.
</blockquote>
<blockquote>
Presenter: Ellen Simms (Editorial Team, SelectScience)
</blockquote>
<blockquote>
Ellen studied biological sciences at the University of the West of England, UK, before completing a master&#39;s in epidemiology from the University of Bristol. As a member of the Editorial team, she now plays an integral role in shaping the content on SelectScience.
</blockquote>

SelectScience: GC-MS solutions for sensory analysis in non-alcoholic beers

GC-MS solutions for sensory analysis in non-alcoholic beers

Semi-targeted method developed using DHS-GC-MS technology that allows for the improvement of NA beer flavor through the addition of specialized hops products.

This webinar will illustrate the GERSTEL Thermal Desorption Unit, highlighting the hardware components, thermal desorption process, and extraction techniques with examples. Additionally, thermal desorption as it pertains to analyte mass on column will be discussed in the context of Sensory Directed Analysis.<h4>Key Takeaways</h4><ul><li>Thermal desorption techniques effectively extract various compounds from a diverse sample set and introduce significantly more analyte mass on column than traditional techniques.</li><li>The GERSTEL TDU has an ideal flow path to ensure optimal transfer of analytes onto the GC-MS.</li></ul><blockquote>Presenter: Megan Harper-Kerr (Applications Scientist, GERSTEL, Inc.)</blockquote>

GERSTEL: Advantages and Capabilities of the GERSTEL TDU for Sample Extraction and Introduction

Advantages and Capabilities of the GERSTEL TDU for Sample Extraction and Introduction

This webinar will illustrate the GERSTEL Thermal Desorption Unit, highlighting the hardware components

GCMS webinars focusing on GC/MS, HeadSpace, Thermal desorption - page 1