Rotary evaporation has long been a staple in laboratories for removing solvents from samples efficiently. However, as technology advances and the demand for higher throughput and more efficient processes increases, alternative methods are becoming more attractive. One such alternative is <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=338">Organomation's S-EVAP evaporators</a>. For laboratories interested in processing several samples simultaneously, the S-EVAP offers significant advantages over multiple rotary evaporators.<h3>Understanding Rotary Evaporation</h3>Rotary evaporation is a technique widely used in chemical and biochemical labs to remove solvents from samples by applying heat and reducing pressure to induce evaporation. The process involves a rotating flask, which increases the surface area for evaporation, making it efficient for solvent removal. Despite its effectiveness, rotary evaporation has limitations, especially when dealing with high-throughput requirements or multiple samples simultaneously.<h3>Criteria for Choosing an Alternative</h3>When selecting an alternative to rotary evaporation, several factors need to be considered:<ul><li>Efficiency: How quickly and effectively can the alternative remove solvents?</li><li>Cost-effectiveness: What is the initial investment and operating cost?</li><li>Ease of use: How user-friendly is the equipment?</li><li>Applicability: Can the alternative handle a variety of solvents and sample types?</li><li>Scalability: Is the method suitable for processing multiple samples simultaneously?</li></ul><h3>Alternatives to Rotary Evaporation</h3><h4>1. Organomation's S-EVAP Evaporators</h4>Organomation's S-EVAP evaporators, available in<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1904"> Kuderna-Danish (KD)</a> and<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1905"> round-bottom (RB)</a> flask models, are designed for laboratories requiring high throughput and efficient solvent removal.&nbsp;<ul><li>S-EVAP KD is available in 8 or 10 position models and can handle sample sizes up to 500 mL</li><li>S-EVAP RB models also offer 8 or 10 positions with capacities up to 250 mL per sample</li></ul>The S-EVAP system is tailored for general evaporation and concentration of analytical or environmental samples using various glassware configurations to meet specific method requirements under controlled and reproducible conditions.This system features rapid solvent evaporation with solvent vapor recovery, achieving solvent recoveries exceeding 96% by volume under ideal conditions.&nbsp;It can operate with cold tap water or a recirculating chiller system, ensuring efficient cooling. The digital controlled water bath provides even and uniform heating without scorching the final samples.&nbsp;The parallel water manifold system ensures even cooling water distribution to each condenser, while the rotary water manifold allows unlimited instrument rotation for easy front loading without condenser tubing entanglement.<h5>Advantages of S-EVAP Over Rotary Evaporation:</h5><ul><li>Higher Throughput: The S-EVAP can process multiple samples simultaneously, significantly increasing throughput compared to using several rotary evaporators.</li><li>Cost-Effectiveness: Although the initial investment may be higher than a single rotary evaporator, the S-EVAP's ability to handle multiple samples at once reduces the need for additional equipment. Lower maintenance costs and reduced need for additional space and infrastructure.</li><li>Ease of Use: User-friendly design with straightforward controls and easy maintenance. Reduced handling time compared to managing multiple rotary evaporators, allowing technicians to focus on other tasks.</li><li>Consistency and Precision: Uniform evaporation conditions ensure consistent results across all samples. Precise control over temperature allows for tailored evaporation conditions for different sample types.</li><li>Space Efficiency: A single S-EVAP unit occupies less space compared to multiple rotary evaporators, making it ideal for labs with limited bench space.</li></ul><h5>Integration in EPA Method 1699</h5>Rotary Evaporator Usage:<ul><li>Initial Solvent Reduction: Rotary evaporators are used first to remove bulk solvent from the sample extract. This step efficiently reduces the volume of the extract to a manageable level under reduced pressure, ensuring that the majority of the solvent is removed without significant loss of analytes.</li><li>Controlled Conditions: The rotary evaporator's ability to control temperature and vacuum precisely helps in handling large initial volumes and reducing them quickly.</li></ul>S-EVAP Evaporator Usage:<ul><li>Further Concentration: After the rotary evaporation step, the concentrated extract is transferred to the S-EVAP system. The S-EVAP evaporators, including the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1904">S-EVAP-KD</a> and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1905">S-EVAP-RB</a> models, are designed to handle smaller volumes and provide a final concentration of the sample.</li><li>Solvent Recovery: The S-EVAP systems offer efficient solvent recovery, with the S-EVAP-RB capable of achieving solvent recoveries exceeding 96% by volume under ideal conditions. This high recovery rate is crucial for environmental and analytical labs that aim to minimize solvent waste and ensure consistent results.</li><li>Even Heating and Cooling: The S-EVAP-RB features a digital controlled water bath for uniform heating, preventing scalding of the final samples. Additionally, the parallel water manifold system ensures even cooling to each condenser, enhancing the efficiency and reproducibility of the evaporation process.</li></ul>Benefits of Tandem Use<ul><li>Enhanced Efficiency: Using both systems in tandem allows for the initial large volume reduction by the rotary evaporator, followed by precise final concentration using the S-EVAP. This combination maximizes throughput and ensures high-quality results.</li><li>Cost and Space Efficiency: The rotary evaporator handles the bulk of the solvent reduction, reducing the strain on the S-EVAP system. This distribution of workload helps in maintaining the equipment and optimizing laboratory space.</li><li>Method Compliance: Following this tandem approach ensures compliance with EPA Method 1699, which outlines specific procedures for pesticide analysis in various environmental samples.</li></ul>Organomation's S-EVAP evaporators, when used in conjunction with rotary evaporators, provide an efficient and reliable solution for laboratories performing high-throughput solvent evaporation tasks, such as those required by EPA Method 1699. This tandem use ensures precise control over the evaporation process, high solvent recovery rates, and consistent sample preparation, making it an ideal approach for environmental and analytical laboratories.<h4>2. Buchi's Syncore Evaporators</h4>Buchi's Syncore evaporators are advanced evaporation systems designed to provide high throughput and efficiency. They use parallel evaporation technology, allowing simultaneous processing of multiple samples under controlled conditions.<ul><li>Applications: Drug discovery, natural product extraction and chemical synthesis</li><li>Advantages: High efficiency with parallel evaporation capabilities, advanced safety features and precise control over evaporation parameters</li><li>Limitations: Potential cost considerations and specific application limitations</li></ul><a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/s-evap-rb-vs-buchi-syncore-download">Download our S-EVAP-RB vs Buchi Syncore comparison with pricing!</a><h4>3. Freeze Drying (Lyophilization)</h4>Freeze drying, also known as lyophilization, is a dehydration process used to preserve perishable materials or make them more convenient for transport. The process involves three main stages: freezing, primary drying (sublimation), and secondary drying (desorption).<ul><li>Applications: Pharmaceuticals, food industry, biological samples.</li><li>Advantages: Long-term stability of dried products.</li><li>Limitations: High cost and time-consuming process.</li></ul>For a more in-depth review, please visit our piece on <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/types-of-laboratory-evaporators">Types of Laboratory Evaporators</a>.<h4>4. Centrifugal Evaporation</h4>Centrifugal evaporation is a technique used to remove solvents from samples by combining centrifugal force, vacuum, and heat. This method is particularly effective for drying samples rapidly and efficiently, making it ideal for high-throughput laboratories.<ul><li>Applications: Used for concentrating and drying biological samples, drug formulations, and other compounds that require gentle handling. Ideal for processing DNA, RNA, proteins, and other sensitive biomolecules.</li><li>Advantages: The combination of centrifugal force and vacuum significantly speeds up the evaporation process compared to traditional methods. Multiple samples can be processed simultaneously, making it suitable for high-volume laboratories.</li></ul>Limitations:<ul><li>Equipment Cost: High-quality centrifugal evaporators can be expensive to purchase and maintain.</li><li>Limited Sample Types: Not all sample types are suitable for centrifugal evaporation, particularly those that require very specific temperature or pressure conditions.</li><li>Technical Expertise: Requires trained personnel to operate the equipment and optimize conditions for different sample types.</li></ul><h4>5. Vacuum Distillation</h4>Vacuum distillation is a technique used to separate mixtures of liquids by utilizing reduced pressure, which lowers the boiling points of the components. This method is particularly useful for separating heat-sensitive compounds that might decompose at higher temperatures.<ul><li>Applications: Used to purify reaction products and separate mixtures in organic synthesis. Essential for refining crude oil into various fractions, such as gasoline, diesel, and lubricants.</li><li>Advantages: Achieves high levels of purity by effectively separating components based on their boiling points. Reduces the risk of thermal decomposition by operating at lower temperatures. Applicable to a wide range of substances, including complex mixtures and heat-sensitive materials.</li></ul>Limitations:<ul><li>Complex Setup: Requires specialized equipment and careful control of vacuum and temperature conditions.</li><li>High Cost: Initial investment and maintenance costs can be high.</li><li>Technical Skill: Operators need to be skilled in managing the distillation process to achieve optimal results.</li></ul><h4>6. Spray Drying</h4>Spray drying is a process used to convert liquid materials into dry powders by rapidly drying them with a hot gas. This technique is widely used in the food, pharmaceutical, and chemical industries for creating stable, shelf-stable powders.<ul><li>Applications: Used to produce powdered milk, coffee, eggs, and flavors. Employed in the production of powdered drugs and formulations.</li><li>Advantages: Efficiently converts liquids into dry powders in a short time. Allows precise control over the size and distribution of the powder particles.</li></ul>Limitations:<ul><li>High Energy Consumption: Requires significant energy to heat the drying gas.</li><li>Thermal Degradation: High temperatures can cause thermal degradation of sensitive compounds.</li><li>Complexity: Requires careful control of operating conditions to achieve desired product characteristics.</li></ul><h4>7. Simple Distillation</h4>Simple distillation is a basic method used to separate liquids with significantly different boiling points. It involves heating the mixture to vaporize the more volatile component, which is then condensed and collected.<ul><li>Applications: Used to purify solvents, water, and other liquids by removing impurities. Ideal for separating simple mixtures of two components with different boiling points.</li><li>Advantages: Easy to set up and operate with minimal equipment. Low initial investment and operating costs. Effective for separating mixtures with large differences in boiling points.</li></ul>Limitations:<ul><li>Limited Precision: Not suitable for separating complex mixtures or components with close boiling points.</li><li>Scalability Issues: Less efficient for large-scale industrial processes.</li><li>Thermal Degradation: Higher temperatures can cause degradation of heat-sensitive components.</li></ul><h4>8. Microwave-Assisted Evaporation</h4>Microwave-assisted evaporation is a technique that uses microwave energy to heat and evaporate solvents from samples. This method is efficient and rapid, making it suitable for various laboratory applications.<ul><li>Applications: Used to speed up reactions and solvent removal in organic synthesis. Employed for drying drug formulations and preparing samples for analysis.</li><li>Advantages: Microwaves heat samples quickly and uniformly, reducing evaporation time.</li></ul>Limitations:<ul><li>Equipment Cost: Microwave evaporators can be expensive to purchase and maintain.</li><li>Sample Compatibility: Not all samples are suitable for microwave heating, particularly those with low dielectric properties.</li><li>Safety Concerns: Requires careful handling to avoid overheating and potential hazards.</li></ul><h3>Conclusion</h3>For laboratories that need to process several samples simultaneously, Organomation's S-EVAP evaporators present a compelling alternative to rotary evaporation. By offering higher throughput, cost-effectiveness, ease of use, and space efficiency, the S-EVAP can streamline laboratory workflows and improve overall productivity. As technology continues to evolve, staying informed about the latest advancements in evaporation methods will ensure that labs can maintain optimal performance and efficiency.

Exploring Alternatives to Rotary Evaporation in Modern Laboratories

Wastewater treatment plants struggle every day with substances that don’t simply disappear from the water. The removal of nitrogen compounds is very important at these plants. If too much of these substances remains in the water, they harm rivers and the life within them. Karel Havlíček from CXI TUL was a co-investigator on the HYMNA project, which combined two well-known treatment technologies into a single system. And he added something to them that isn’t commonly used at treatment plants: nanofibers.The full name of the project is “Hybrid MBR-MBBR System Using Nanomaterials for Advanced Wastewater Treatment.” The acronym is HYMNA. “It sounds a bit grand,” laughs co-investigator Karel Havlíček from the Department of Environmental Protection Technology. But the goal was indeed grand. The water that flows out of a treatment plant isn’t always as clean as it could be. And that’s a problem worth solving.<h4>A Screen and Beads</h4>Behind the acronyms MBR and MBBR lie two technologies that treatment plants typically deploy separately. But Karel combined them into a single process and demonstrated that together they can work significantly better. He validated the combination in practice and used it to design a technology with a clear procedure, measurable results, and the potential for real-world application.The MBR functions as a fine screen. The membranes trap impurities, organic matter, and undissolved particles. But even then, the process isn’t complete—nitrogenous compounds still remain in the clarified water.To address this, Karel Havlíček and his partners implemented the second part of the technology: MBBR. Small plastic beads with holes and nanofibers inside move freely in the tank with the help of aeration. Microorganisms grow and live on the surface of the nanofibers, converting ammonia nitrogen into nitrates.Why does this matter? Ammoniacal nitrogen is toxic to fish; it damages their gills and, at higher concentrations, kills them. An excess of nitrogen triggers algae blooms, causing the water to turn green, depleting oxygen levels, and suffocating aquatic life.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_2_6559ff2373.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_2_6559ff2373.jpg 117w," sizes="100vw" width="768" height="1024"><h4>Beads with a Nanofiber Core</h4>The beads are no accident. Karel inserted nanofiber carriers—a fine fibrous material to which microorganisms quickly and firmly attach—into plastic bodies with holes. He had already proposed this concept in his dissertation.The path to the final design was not straightforward. Originally, it was a nanofiber layer. However, it gradually washed off the beads. They replaced it with yarn, which holds its shape. The result is a utility model for new biomass carriers.The main advantage is the speed of colonization. On conventional materials, colonization takes much longer. Microorganisms colonize the nanofibers quickly. This is crucial, especially where the water is hostile or toxic to them.Industrial wastewater is often so polluted that bacteria cannot survive on conventional carriers. On a nanofiber surface, however, they manage to attach themselves before the environment destroys them. The system then works even where other technologies would fail.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_3_290e60625f.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_3_290e60625f.jpg 117w," sizes="100vw" width="768" height="1024"><h4>A Surprising Number</h4>The most important factor was how the system would handle ammonia nitrogen. The team even tested extreme concentrations of up to eighty milligrams per liter. And that’s not just fine-tuning. That’s a stress test pushing the limits—one that could cripple or completely halt the activity of the purifying microorganisms.The system handled it. At the outflow, they measured less than one milligram per liter.“We achieved a level that even a conventional treatment plant often can’t handle,” Karel said, expressing his surprise.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_4_00a10f7915.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_4_00a10f7915.jpg 117w," sizes="100vw" width="768" height="1024"><h4>Container-Based Treatment Plant</h4>Combining the two technologies brought an added benefit. The system can function not only as a post-treatment unit following a standard treatment plant but also as a standalone modular treatment plant. No construction is needed; the system can be delivered, connected, and put into operation.“Industrial facilities will especially appreciate this. Companies that currently transport contaminated water in barrels as hazardous waste could handle part of the treatment themselves,” explains Karel. According to him, this would mean less waste, less logistics, and lower costs for companies.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_5_15c7bfefc3.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_5_15c7bfefc3.jpg 117w," sizes="100vw" width="768" height="1024"><h4>A Myth That Didn’t Pan Out</h4>Apart from the main project, Karel’s team asked themselves another question: Can microorganisms in a standard wastewater treatment plant biofilm on carriers break down micropollutants—that is, traces of medications or pesticides that end up in the water?Some studies suggested that this might be possible.But the enthusiasm quickly faded. “No degradation occurs. The micropollutants simply accumulate in the system,” Karel states. The system captures them but does not destroy them. That requires more powerful methods, such as ozone or UV radiation.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_f8251f3b2e.jpg" alt="CXI TUL: Beads with a nanofiber core. This is a better way to purify water." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CXI_TUL_Kulicky_s_nanovlakennym_srdcem_Takhle_se_da_cistit_voda_lip_f8251f3b2e.jpg 110w," sizes="100vw" width="724" height="1024">The HYMNA project, part of the TREND program of the Technology Agency of the Czech Republic, in collaboration with ENVI-PUR, s.r.o. (principal investigator) and Pražské vodovody a kanalizace, a.s.

Beads with a nanofiber core. This is a better way to purify water.

In this episode of Concentrating on Chromatography, we sit down with Dr. Lee Polite from Axion Training Institute to break down one of analytical chemistry's most powerful yet misunderstood techniques: gas chromatography-mass spectrometry (GC/MS).<h4>What You'll Learn:</h4><ul><li>Why GC and MS are the "perfect pair" – and what happens when you try to use MS alone</li><li>The electron gun: how molecules get ionized and why they become positively charged (not negatively!)</li><li>The magnetic sector vs. quadrupole: from first principles to modern mass filtering</li><li>Why Dr. Lee uses the "corkscrew trajectory" analogy – and why it actually works</li><li>The cars and boats analogy: how fragmentation creates a unique molecular fingerprint</li><li>Scan mode vs. SIM (Selected Ion Monitoring): when to use each for identification vs. sensitivity</li><li>Real-world forensics: detecting pesticides in spinach and cocaine in hair follicles</li><li>Triple quad GC/MS and Multiple Reaction Monitoring (MRM): the future of trace analysis</li></ul><h4>Why This Matters:</h4>Over 2 million chromatographs operate worldwide, yet most users don't truly understand how they work. Dr. Polite has trained more than 14,000 professional scientists at Axion Labs to move beyond "pushing buttons" to genuinely comprehending the science. This conversation is designed for undergraduate students, academic researchers, and anyone preparing for analytical chemistry roles in pharma, environmental testing, or forensics. &nbsp;🎤 Dr. Lee Polite is a leading authority in analytical chromatography education and founder of Axion Training Institute, a real working laboratory where scientists come for hands-on GC and LC training. With nearly 30 years of experience and a PhD under Harold McNair (one of the grandfathers of modern chromatography), Dr. Polite is passionate about making complex instrumentation accessible to students and professionals alike.<h3>Video Transcription</h3>Mass spectrometry has a reputation for being one of the most intimidating analytical techniques. According to Dr. Lee Polite, however, that reputation is undeserved. During a recent interview, the founder of Axion Analytical Labs shared how decades of teaching scientists—from undergraduate students to forensic chemists and even lawyers—have convinced him that virtually anyone can understand GC/MS when the concepts are explained correctly.His approach relies less on equations and more on analogies, transforming complex physical principles into familiar everyday experiences.<h4>The biggest misconception about mass spectrometry</h4>"The first obstacle isn't the science—it's the belief that you'll never understand it."That is the misconception Dr. Polite encounters most often. Students frequently enter chromatography or mass spectrometry courses assuming the subject is too complex for them.His advice is simple: suspend that disbelief.Rather than viewing GC/MS as one enormous complicated system, he encourages learners to see it as a collection of simple processes connected together. Once each individual step becomes clear, the entire instrument suddenly makes sense.<h4>Teaching more than 14,000 scientists</h4>Dr. Polite founded Axion Analytical Labs nearly three decades ago. Although it operates as a fully functional chromatography laboratory, its primary mission is education.Scientists spend five days in the laboratory learning chromatography hands-on—disassembling instruments, rebuilding them, troubleshooting problems, and developing a practical understanding of how the technology works.Over the years, Axion has trained more than 14,000 scientists, along with hundreds of attorneys who need to understand analytical chemistry for courtroom testimony. Dr. Polite believes curiosity matters far more than formal education.<h4>Why every GC needs a mass spectrometer—and every mass spectrometer needs a GC</h4>One of the interview's clearest explanations addresses a question many beginners ask:<h5>Why do we combine gas chromatography with mass spectrometry?</h5>The answer lies in the strengths and weaknesses of each technique.Mass spectrometers excel at identifying pure compounds, but they struggle with complex mixtures. Real-world samples—environmental extracts, food, pharmaceuticals, forensic evidence—are almost always mixtures.Gas chromatography solves this problem by separating the mixture into individual components before they reach the mass spectrometer.As Dr. Polite summarizes:<blockquote>GC provides the separation power. Mass spectrometry provides the identification power.</blockquote>Without chromatographic separation, overlapping compounds generate confusing spectra that are difficult—or impossible—to interpret correctly.<h4>Explaining chromatography with a shopping mall</h4>Perhaps Dr. Polite's most famous teaching analogy compares chromatography to walking through a shopping mall.Imagine two people standing on a moving walkway. One walks straight through the mall, while the other repeatedly leaves the walkway to browse clothing stores, shoe stores, and accessory shops.Although both entered together, they exit at different times.Chromatographic separation works in exactly the same way. Every compound enters the column simultaneously, but molecules interact differently with the stationary phase. Those with stronger interactions spend more time "shopping" and therefore elute later.The analogy immediately illustrates retention time without requiring advanced chemistry.<h4>How can a mass spectrometer "weigh" molecules?</h4>Another concept that often confuses students is molecular weight determination.Since molecules are far too small to weigh directly, mass spectrometers first convert neutral molecules into ions using electron impact ionization.Once charged, the ions can be manipulated by electric or magnetic fields.Dr. Polite introduces the concept by first describing the historical magnetic sector instrument before moving to the quadrupole mass filter used in most modern GC/MS systems.His explanation replaces intimidating mathematics with a simple idea: only ions having the correct mass-to-charge ratio can successfully travel through the quadrupole and reach the detector.<h4>Fragmentation: the molecular fingerprint</h4>Simply measuring molecular weight rarely identifies a compound uniquely.The real power of GC/MS comes from fragmentation.High-energy electrons break molecules into characteristic fragments that create a unique mass spectrum—a molecular fingerprint.To explain this process, Dr. Polite asks readers to imagine a car packed with explosives. After the explosion, investigators identify the vehicle by examining scattered components such as wheels, doors, and the steering wheel.Mass spectrometry works the same way.Each fragment contributes evidence that allows software libraries, such as NIST, to determine compound identity with remarkable confidence.<h4>Scan mode versus SIM mode</h4>The interview also explores the practical difference between scan acquisition and Selected Ion Monitoring (SIM).Scan mode records a complete mass spectrum and is ideal for identifying unknown compounds.SIM, on the other hand, focuses only on a few selected ions, dramatically increasing sensitivity.Using pesticide analysis as an example, Dr. Polite demonstrates how compounds that are almost invisible in full-scan chromatograms become obvious when monitored using SIM.<h4>Why triple quadrupoles dominate trace analysis</h4>For laboratories measuring contaminants at parts-per-trillion concentrations, triple quadrupole instruments provide another major advantage.Instead of monitoring only a single ion, tandem MS follows a specific fragmentation pathway—known as a transition—greatly reducing background interference.This Multiple Reaction Monitoring (MRM) approach enables highly selective quantification of pesticides, PFAS, pharmaceutical residues, and numerous other trace contaminants in extremely complex samples.<h4>The chromatography lesson many users forget</h4>One message appears repeatedly throughout the interview:Most GC/MS problems are actually chromatography problems.Poor separations inevitably produce poor mass spectra.Dr. Polite argues that successful mass spectrometry begins with understanding chromatography fundamentals rather than relying on sophisticated detectors to compensate for inadequate separations.<h4>Looking ahead</h4>When asked about the future of mass spectrometry, Dr. Polite predicts continued improvements in sensitivity, smarter software, and increasing use of artificial intelligence.AI could assist laboratories by automatically recognizing problematic chromatographic peaks, identifying developing instrument issues, and simplifying interpretation of increasingly complex datasets.Yet despite these technological advances, he believes the fundamentals remain unchanged.Scientists who understand chromatography, ionization, fragmentation, and data analysis will continue to benefit regardless of how instrumentation evolves.<h4>Final thoughts</h4>After teaching analytical chemistry for more than 30 years, Dr. Lee Polite remains convinced that mass spectrometry is not inherently difficult.The challenge is rarely the science itself—it is finding the right explanation.By combining memorable analogies with practical laboratory experience, he demonstrates that one of analytical chemistry's most powerful techniques can also be one of its most approachable.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.<h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

How Mass Spectrometry Actually Works: The Quadrupole Explained

Article

Product

Academy

Video

Environment

Water

Interview

Science and research

The Institute for Nanomaterials, Advanced Technologies and Innovations of the Technical University of Liberec, also known as CXI TUL, was founded in 2009. Our mission is to support TUL's long-term vision of collaboration with industry and innovation.

CXI TUL

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Anton Paar

Agilent Technologies

LECO

Thermo Fisher Scientific

SciY/Mestrelab Research

Waters Corporation

<div><h4>Navigating Challenges and Opportunities for Environmental Testing Labs Under the Revised EU Water Framework Directive</h4>The European Commission’s proposed updates to the Water Framework, Groundwater, and Environmental Quality Standards Directives are bringing new responsibilities and opportunities for environmental testing labs. With expanded pollutant lists - including PFAS, pharmaceuticals, and pesticide metabolites - and stricter monitoring and reporting requirements, the landscape of water analysis is rapidly evolving.Join the 4th Waters Environmental Webinar Series to explore how your lab can navigate these challenges and turn regulatory change into opportunity.Register for free and partner with us to shape the future of European water quality.<h5>Why Attend</h5>Stay ahead of new EU regulatory demands with insights from leading experts. Gain practical guidance, share experiences with peers, and prepare your lab for the next generation of water quality standards.<h5>Highlights</h5><ul><li>New pollutant categories and analytical challenges</li><li>Updates to monitoring protocols and reporting</li><li>Innovative methods to meet revised Environmental Quality Standards</li><li>Strategic guidance for compliance and adaptation</li></ul>Lead the change in water analysis—stay ahead, stay compliant, and make a real impact.<h4>EPISODE 6: Blue Thursdays 2026 – The Best Of</h4>In this final session, we’ll look back at the most important things we’ve learned throughout the Blue Thursday series. We’ll explore the big trends we’re seeing, the smart tools scientists use to study the environment, and what exciting developments will be coming next.<blockquote>Speaker: Claudia Rathmann (Principal F&amp;E Market Development Manager, Waters Corporation)Experienced and passionate analytical science professional with over 20 years of technical and strategic expertise in food and environmental applications. Currently serving as Principal Market Development Manager at Waters Corporation, Claudia specializes in connecting customers with product management to deliver innovative solutions for complex analytical challenges. With a strong scientific foundation and a proven track record in both technical and marketing roles, Claudia bridges the gap between customer needs and product innovation across the EMEA region.Speaker: Janitha De-Alwis (JD) (Principal F&amp;E Market Development Manager, Waters Corporation)Janitha De-Alwis (known as JD) is an applications chemist in the European demo lab, based in Wilmslow, UK. His main role focuses on application development work for the food and environmental sector. JD takes great pride in speaking to, and advising, many food and environmental customers. His position requires him to be reactive and proactive to the changes in the food industry, such as changing regulations, topical issues and food safety risks.</blockquote></div>

Blue Thursdays 2026 – The Best Of

In this final session, we’ll look back at the most important things we’ve learned throughout the Blue Thursday series.

We probably have all experienced this at some point when performing gas chromatography and our peak shape begins to appear a bit different. &nbsp;In this webinar, we will discuss some of the most common chromatographic issues that you experience with Gas Chromatography and take a logical approach to finding the root cause and correcting the problem. Often the best way to approach troubleshooting is to also consider what ‘cannot’ cause an issue so that precious time is not spent addressing something that cannot cause the issue. This webinar will arm you with some simple tools, and a different way to look at troubleshooting, should a problem arise.<blockquote>Speaker: Alex Ucci&nbsp;In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.</blockquote>

Agilent Technologies: Becoming A Better Chromatographer Webinar Series

Essential Techniques for Gas Chromatography Troubleshooting

Learn essential GC troubleshooting techniques with Agilent. Discover a logical, time-saving root-cause analysis approach to fix poor peak shapes

Essential Techniques for GC Troubleshooting

This presentation will cover products from Agilent that make GC connections more robust by utilizing new technologies that make connections easier, leak free and more inert for any application.Topics covered include: Self Tightening Stainless Column Nuts and ferrules, Press Fits, UltiMetal Plus and Stainless Steel Capillary Tubing, Ferrule Pre-swaging installation tool and MS interface installation tool, among others.<blockquote>Speaker: Mark Sinnott (Technical Support Engineer, Consumables and Supplies Division, Agilent Technologies)Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Twin Falls Idaho.</blockquote>

Agilent Technologies: Becoming A Better Chromatographer - GC Webinar Series

From Inlet to Detector: Building Better Connections in GC and GC/MS Workflows

Build better GC and GC/MS connections with Agilent. Explore self-tightening column nuts, pre-swaging tools, and inert capillaries to eliminate leaks

Building Better Connections in GC and GC/MS Workflows

Keeping your GC system running smoothly isn’t just about good method development; it’s also about being prepared. In this webinar, we’ll walk through the essential consumables every lab should keep on hand to avoid unnecessary downtime. &nbsp;From gas traps and syringes to columns and detector supplies, we will discuss what supplies to stock and how this can help save valuable time.If you are about to purchase an instrument, we will also discuss critical items you’ll need to have on hand to ensure the installation is completed smoothly.Whether you’re new to GC or looking to optimize your workflow, this webinar will help ensure your system and your lab team stay up and running.<blockquote>Speaker: Ryan Mayfield (Field Service Engineer, Agilent Technologies)Ryan Mayfield has over 11 years of experience as a Field Service Engineer supporting GC and GCMS systems. &nbsp;He also delivers on-site application consulting for customers across a wide range of industries, including environmental, biotech, and petrochemical fields. &nbsp;He has a BS and MS in Food Science from UC Davis.Additional Speaker: Alex Ucci (Application Engineer, Agilent Technologies)In his current position at Agilent, Alex provides application assistance and technical support for sample preparation products as well as GC and LC consumables. Before he joined Agilent in 2014, Alex was a graduate student at the Pennsylvania State University researching the morphology and surface properties of aerosol particles using a wide variety of analytical techniques. He has an MS degree in chemistry.</blockquote>

Stocked for Success: Essential GC Supplies That Keep You Running

Stay prepared with essential GC supplies. Explore critical consumables, gas traps, and detector supplies needed to prevent downtime and ease installation

Essential GC Supplies to Keep Your System Up and Running

<div><div id="inner_content_body_text" data-content-id="394785">Polymers are complex materials, and understanding their performance requires more than just mechanical testing. Rheology provides valuable information on viscosity, elasticity, and flow, but it cannot fully explain the chemical and structural changes that occur during processing. By integrating rheology with Raman spectroscopy, researchers and engineers can correlate mechanical behavior with molecular-level insights in real time.This combined Rheo-Raman approach opens up new possibilities for understanding polymerization, crystallization, and thermal stability, supporting better formulation, troubleshooting, and quality control across the polymer industry.<h4>Key Learning Topics:</h4><ul><li>How Rheo-Raman correlates mechanical properties with chemical structure to deliver deeper insights into polymer behavior</li><li>How to monitor polymerization reactions and chemical transformations in real time</li><li>How to study crystallization pathways and their impact on material performance</li><li>How to assess thermal stability and degradation during processing or use</li><li>How Rheo-Raman supports faster material development, improved quality control, and problem-solving in industrial and research settings</li></ul><blockquote>Presenter: James P. Eickhoff Jr.James Eickhoff is the principal application engineer for the rheology division as a member of the Advanced Technical Support Center at Anton Paar USA. He has over 20 years of theoretical and experimental rheology training, including the last 17 years with Anton Paar having guided current and prospective customers on the use of rheological techniques in their industrial and academic research. James earned a Bachelor’s and Master’s Degree in Chemical Engineering from Michigan Technological University and Clemson University, respectively.</blockquote></div></div>

Anton Paar: Correlating Mechanical and Chemical Properties: Introduction to Rheo-Raman for Polymers

Correlating Mechanical and Chemical Properties: Introduction to Rheo-Raman for Polymers

Learn how Rheo-Raman combines rheology and Raman spectroscopy to study polymerization, crystallization, and polymer performance in real time.

Introduction to Rheo-Raman for Polymers

As materials become increasingly sophisticated, understanding their optical properties is essential for driving innovation, improving product performance, and ensuring quality. Whether developing anti-reflective coatings, optimising solar cell efficiency, designing specialty glass, or researching next-generation materials, accurate optical characterisation is a critical part of the workflow.Join us for this webinar to discover how the Agilent UV-Vis-NIR spectrophotometer enables researchers and industry professionals to measure and characterise a broad range of optical properties across diverse sample types and applications.The webinar will showcase measurement techniques for transmission, reflectance, diffuse reflectance, and angular measurements, highlighting how the Agilent UV-Vis-NIR platform delivers reliable and reproducible data for both research and industrial applications.<h4>Why Attend?</h4>In this session, you will learn:<ul><li>How the Agilent UV-Vis-NIR can be used to characterise thin films, coatings, solar materials, and glass.</li><li>Techniques for measuring transmission, reflectance, and diffuse reflectance with confidence.</li><li>Methods for determining film thickness and evaluating optical performance.</li><li>How specialised accessories expand measurement capabilities for challenging samples.</li><li>Best practices for obtaining accurate, reproducible results across a variety of applications.</li><li>Real-world examples demonstrating how optical measurements can accelerate research and product development.</li></ul><h4>Who Should Attend?</h4>This webinar is designed for:<ul><li>Academic Researchers and Students<ul><li>Researchers in materials science, physics, chemistry, and engineering.</li><li>Scientists investigating thin films, nanomaterials, optical materials, and photonic devices.</li><li>Graduate students and postdoctoral researchers seeking advanced optical characterisation techniques.</li></ul></li><li>Solar and Photovoltaics<ul><li>Scientists and engineers developing solar cells and photovoltaic materials.</li><li>Researchers evaluating anti-reflective coatings and light management strategies.</li><li>Teams working to improve solar cell efficiency through optical optimisation.</li></ul></li><li>Glass and Coatings Industries<ul><li>Manufacturers of architectural, automotive, and specialty glass.</li><li>Researchers developing low-emissivity and anti-reflective coatings.</li><li>Quality control and R&amp;D professionals responsible for optical performance testing.</li></ul></li><li>Advanced Materials and Industrial R&amp;D<ul><li>Thin film and semiconductor researchers.</li><li>Optical coating manufacturers.</li><li>Scientists working with displays, sensors, filters, and advanced functional materials.</li><li>Analytical laboratories requiring precise optical characterisation.</li></ul></li></ul><h5>Featured Applications</h5><ul><li>Thin film and multilayer coating analysis</li><li>Anti-reflective and optical coating characterisation</li><li>Solar cell and photovoltaic material evaluation</li><li>Optical filter transmission and blocking measurements</li><li>Architectural and specialty glass analysis</li><li>Reflectance measurements at varying angles of incidence</li><li>Film thickness determination</li><li>Diffuse reflectance measurements of scattering materials</li><li>Optical characterisation of emerging materials in academia and industry</li></ul>Discover how the Agilent UV-Vis-NIR platform combines exceptional optical performance, flexible sampling accessories, and intuitive workflows to provide the insights needed to advance research, optimise products, and solve challenging analytical problems.<blockquote>Presenter: Mr. Rajwar Chandra (Product Specialist - Spectroscopy, Agilent Technologies)Chandra Rajwar is a Product &amp; Market Specialist with over 20 years of experience in Molecular Spectroscopy products and analytical instrumentation. He specializes in UV-Vis, FTIR, Raman, and related spectroscopy solutions, supporting customers with application development, workflow optimization, and analytical excellence across pharmaceutical, chemical, environmental, and research industries.</blockquote><blockquote>Presenter: Ms. Vijaya Jyothi (Product Specialist - Spectroscopy, Agilent Technologies India Pvt. Ltd.)Vijaya Jyothi is a seasoned product specialist at Agilent Technologies. She manages the spectroscopy division, having extensive expertise in spectroscopy applications across diverse industries, offering deep insights and solutions tailored to varied analytical needs.</blockquote>

Agilent Technologies: Characterising Advanced Materials with the Agilent UV-Vis-NIR - From Thin Films and Solar Cells to Glass and Optical Coatings

Characterising Advanced Materials with the Agilent UV-Vis-NIR: From Thin Films and Solar Cells to Glass and Optical Coatings

Characterize thin films, solar cells, and coatings with Agilent UV-Vis-NIR. Master reflectance, transmission, and angular measurement workflows

Materials Characterization with Agilent UV-Vis-NIR

Diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) is a powerful technique for investigating catalyst surface chemistry under reaction conditions. In this live webinar, subject matter specialists from Michigan State University, Specac, and Thermo Fisher Scientific will discuss how in situ DRIFTS can be used to study dry reforming of methane over ceria-supported catalysts and provide insight into the surface species and reaction intermediates involved in catalytic CO₂ utilization.The session will explore DRIFTS experimental setup considerations, approaches for relating spectral observations to catalyst behavior, and examples of how researchers use in situ spectroscopy to investigate CO₂ activation and metal-support interactions. Presenters will also discuss complementary characterization techniques, including CO-DRIFTS, CO₂-DRIFTS, and CO₂-TPD-DRIFTS, and their role in catalyst research workflows.Attendees will be able to gain practical knowledge that can help strengthen catalyst characterization strategies, support experimental design, and improve interpretation of catalyst behavior in heterogeneous catalysis research.<h4>Key takeaways</h4>By attending this webinar, you can learn several aspects about this specific method of analysis:<ul><li>Apply in situ DRIFTS to investigate catalyst surface chemistry under reaction conditions</li><li>Monitor adsorbed species and reaction intermediates during dry reforming of methane</li><li>Relate spectral observations to catalyst behavior and reaction mechanisms</li><li>Investigate CO₂ activation and metal-support interactions in ceria-supported catalyst systems</li><li>Evaluate when to use complementary techniques such as CO-DRIFTS, CO₂-DRIFTS, and CO₂-TPD-DRIFTS</li><li>Incorporate DRIFTS into catalyst characterization workflows to support more informed research and development decisions.</li></ul><h4>Who should attend</h4><ul><li>Catalysis researchers</li><li>Materials scientists</li><li>Surface scientists</li><li>FTIR and vibrational spectroscopy users</li><li>Academic researchers studying heterogeneous catalysis</li><li>Scientists involved in catalyst development and characterization</li><li>Researchers working in CO₂ utilization, carbon management, and sustainable catalysis</li></ul><blockquote>Presenter: Md Monir Hossain, PhD Candidate, Michigan State UniversityResearcher focused on heterogeneous catalysis, carbon utilization, and DRIFTS studies of ceria-supported catalysts for dry reforming of methane.Presenter: Jim Delaney, Applications Team Lead, SpecacLeader of global spectroscopy application development and customer engagement efforts, supporting advanced research and industrial spectroscopy workflows.Presenter: Lena Woodis, PhD Product Manager, Thermo Fisher ScientificVibrational spectroscopy veteran with more than 15 years of experience in chemical instrumentation, FTIR spectroscopy, and analytical technologies.</blockquote>

Thermo Fisher Scientific: From Spectra to Mechanism: Using DRIFTS to Understand CO₂ Catalysis

From Spectra to Mechanism: Using DRIFTS to Understand CO₂ Catalysis

In this webinar, subject matter specialists will discuss how in situ DRIFTS can be used to study dry reforming of methane over ceria-supported catalysts.

Using DRIFTS to Understand CO₂ Catalysis

Exhaled breath is increasingly recognized as a powerful source of molecular information for personalized medicine. Containing hundreds to thousands of volatile organic compounds (VOCs) that reflect metabolic, inflammatory, microbiological, and environmental processes, breath offers a unique, completely non-invasive window into human health. Yet, unlocking this chemical complexity requires analytical platforms capable of delivering both exceptional separation power and high-confidence molecular characterization.At the forefront of this evolution is comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GCxGC-MS), which has emerged as a cornerstone technology in modern breathomics. By significantly expanding chromatographic peak capacity and resolving power compared with conventional one-dimensional approaches, GCxGC-MS enables a more comprehensive exploration of the human volatilome and facilitates the discovery of clinically relevant biomarkers that would otherwise remain undetected.This webinar will explore how advanced GCxGC-MS workflows are transforming breathomics research and accelerating its translation towards clinical implementation. Drawing on recent developments in untargeted and targeted analytical strategies, we will discuss how comprehensive volatilome profiling can be integrated with rapid and streamlined methodologies to create efficient multi-platform pipelines for biomarker discovery, validation, and routine application. Particular emphasis will be placed on the critical role of analytical design, quality control, and data processing in generating robust and reproducible results from highly complex breath samples.Beyond technology development, the presentation will address the key challenges facing the field, including standardization of sampling protocols, harmonization of analytical methodologies, and the transition from exploratory studies to clinically actionable solutions. Real-world applications will illustrate how breathomics can support disease detection, patient stratification, therapeutic monitoring, and precision healthcare.As analytical capabilities continue to advance, GCxGC-MS is positioning breathomics to move beyond proof-of-concept studies and towards a future where non-invasive molecular phenotyping becomes an integral component of personalized medicine.<blockquote>Speaker: Anaïs Rodrigues (Applications Chemist, LECO Europe)</blockquote><blockquote>Speaker: Pierre-Hugues Stefanuto (Lead Scientist &amp; Senior Lecturer, Liège University, Belgium)</blockquote>

LECO: Breathomics - Advancing Personalized Medicine Through Next-Generation Analytical Solutions 

Breathomics: Advancing Personalized Medicine Through Next-Generation Analytical Solutions

Discover how GCxGC-MS transforms breathomics and VOC profiling. Learn how non-invasive molecular phenotyping enables personalized medicine

Breathomics & GCxGC-MS for Personalized Medicine

Laboratories are under growing pressure to handle increasing volumes of samples and data while operating under tighter regulatory inspection, all without compromising turnaround times or traceability. In this context, many organizations attempt to extend existing workflows and legacy tools, which can introduce inefficiencies, increase manual effort, and create compliance risks. At the same time, it is not always clear which digital solutions are best suited to address these challenges.This presentation illustrates how modern digital laboratory environments streamline routine activities by minimizing manual tasks and embedding compliance directly into everyday workflows. Drawing on a real-world use case, we show how automated capture of data from multiple sample measurements at the point of execution enables a continuous, sample-centric workflow.By removing manual interventions and paper-based processes, laboratories can improve efficiency and visibility, support faster and more reliable decision-making while remaining responsive to evolving customer demands.<h4>Learning Points</h4><ul><li>The role of different systems (LIMS, SDMS, ELN) within the digital lab landscape and how they differ from each other's</li><li>How WebLab manages laboratory operations from a sample perspective, enabling you to track every sample, stage, and next action across workflows</li><li>How automated data capture from connected instruments helps reduce errors, lower contamination risks, and accelerate sample processing</li><li>You will see, through a real-life example, how integrated digital workflows improve data quality, accelerate reporting, and increase operational efficiency</li></ul><h4>Who should attend</h4>Professionals working in small to mid‑sized laboratories, including:<ul><li>Directors and Managers of Analytical, QC, or Contract Labs</li><li>Lab Operations and QA/QC Leaders</li><li>Digitalization and IT at organizations transitioning from paper, Excel, or legacy systems to LIMS</li></ul><blockquote>Presenter: Peter Bellstedt, PhD (Director of Business Development and Product Manager at SciY)Peter studied Biochemistry at the University of Jena before completing a PhD on the structural characterization of a DNA repair protein using solution and solid-state NMR. He was then appointed as the head of the NMR Spectroscopy Platform in Jena, Germany, where he pioneered the implementation of modern, highly efficient data-driven workflows. After five years, he moved to the University of Zurich, Switzerland, as a principal investigator, where his lab focused on structure-based drug discovery. This year, he brought his wealth of experience to the LOGS by SciY team, focusing on efficient workflow solutions for research labs and facilities on a global scale.</blockquote>

SciY: From Legacy Workflows to Paperless Labs: Track Every Sample, Process, and Decision

From Legacy Workflows to Paperless Labs: Track Every Sample, Process, and Decision

Transition from paper to a paperless lab. Discover how WebLab, LIMS, and automated data capture streamline sample tracking and boost compliance

Paperless Labs & Sample Tracking: Digital LIMS Workflows

The challenge of developing and maintaining robust chemometric models for use within Process Analytical Technology (PAT) deployment remains a significant barrier to implementation. This webinar explores how Iterative Optimization Technology (IOT) is advancing the principles of lean chemometrics by reducing the calibration burden associated with PAT deployment. Case studies will demonstrate how these methods enable faster model deployment, improved lifecycle management, and greater operational efficiency without compromising product quality or process understanding. Attendees will gain insights into how innovative chemometric strategies can accelerate PAT adoption while supporting the industry's drive towards agile, data-driven manufacturing.<h4>Learning Points</h4><ul><li>You will learn how lean chemometrics reduces model complexity and data requirements</li><li>Discover how to simplify model deployment and lifecycle management</li><li>Explore how to accelerate PAT adoption while maintaining process understanding and quality</li></ul><h4>Who should attend</h4><ul><li>Process development and MSAT teams scaling processes to manufacturing</li><li>PAT scientists and analytical experts developing chemometric models</li><li>Lab managers driving efficient and scalable PAT implementation</li><li>Development and manufacturing and digitalization leaders advancing data-driven operations</li></ul><blockquote>Presenter: Jonique Samuels (Scientific Advisor for Innovations, SciY)Jonique Samuels is a Scientific Advisor for Innovations at SciY where she leads research and development projects on new, novel functionality for synTQ, the orchestration and real-time process-control platform that enables PAT and advanced, quality-centric control strategies. Currently, Jonique's focus is on supporting sustainability initiatives with customers, which includes investigating and developing lean chemometrics methods.&nbsp;</blockquote><blockquote>Presenter: Anna Codina, Ph.D. ( Senior Director Strategy and Business Development, SciY)Anna Codina is Senior Director of Strategy and Business Development at SciY, where she focuses on enabling data-driven orchestration across the pharmaceutical value chain. With a background in experimental science, analytical development, and digital innovation, she works at the intersection of data, automation, and AI to accelerate scientific workflows and decision-making.Anna holds a Ph.D. in protein NMR from the University of Barcelona and completed postdoctoral research at the MRC Laboratory of Molecular Biology in Cambridge. She spent seven years in Analytical R&amp;D at Pfizer, specializing in reaction monitoring, impurity characterization, and regulatory submissions, and was recognized with a Pfizer Worldwide Achievement Award for implementing NMR-based reaction monitoring in an open-access environment.Since joining Bruker, Anna has held multiple leadership roles across applications, product management, and biopharma business development and market management. In her current role at SciY, she drives strategy for vendor-agnostic data platforms and digital solutions that connect instruments, robotics, and enterprise systems enabling orchestration, AI-powered experimentation and scalable workflows across R&amp;D, CROs/CDMOs, and manufacturing.</blockquote>

SciY: Advancing Lean Chemometrics: Iterative Optimization Technology as a Process Analytical Technology Tool for Reducing Calibration Burden

Advancing Lean Chemometrics: Iterative Optimization Technology as a Process Analytical Technology Tool for Reducing Calibration Burden

Reduce PAT calibration burden with Lean Chemometrics and IOT. Learn to accelerate model deployment and simplify lifecycle management in this webinar

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