<blockquote><p>Welcome back to the topic of protecting your GC column! <strong>If you missed part 1</strong> or would like to refresh your knowledge, find further tips on GC column protection <a target="_blank" rel="noopener noreferrer" href="https://www.phenomenex.com/knowledge-center/gc-knowledge-center/protecting-your-gc-column-pt1-tech-tip-en-1025"><strong>here</strong>.</a></p></blockquote><p><strong>Protecting your GC column and instrument components from exposure to dirty samples or contaminants is important. Non-volatile or high molecular weight components can contaminate the stationary phase, causing poor peak resolution, lower accuracy, and poor column lifetime. Cutting off the damaged portion of column tubing will often restore your column’s performance, but over time performance will degrade to a point where the column can no longer be used. If you are experiencing rapid degradation of column performance, there are several simple ways to help protect your column and increase its lifetime.</strong></p><h3><strong>Use A Liner With Wool</strong></h3><p>The liner is the first line of defense for your column, and the style you choose can make a big impact in how much contamination gets onto the column. The easiest thing to do is to add a small amount of silanized glass wool to a liner, which traps the non-volatile compounds and prevents them from entering directly into the column.&nbsp;</p><blockquote><p><strong>Caution: </strong>glass wool can also add activity for acids, bases, and pesticides. Crushing the glass wool can expose undeactivated glass and free silanols (-OH groups) even if the wool has been deactivated. This leads to increased activity, so pre-packed liners, rather than self-packed ones are highly recommended to avoid reproducibility issues.</p></blockquote><p>In addition to choosing a liner with wool, ensure that your liner (and other system consumables) are free of contaminant build-up that may form over time. Septum cores and other particulates that remain can become trapped in the wool and are sometimes difficult to spot. Regularly replace the liner (and other system consumables as needed) to reduce troubleshooting and maintenance.</p><h3><strong>Bake Out Your Column</strong></h3><p>The easiest way to reduce column contamination is to add a short, high temperature bake-out at the end of your standard GC method. This bake out helps remove high boiling contaminants that would otherwise remain in the column and cause damage. To bake out, the final oven temperature needs to be set high enough to ensure elution of these compounds, but not so high as to cause thermal damage. This can be done either isothermally, or more commonly, via an oven ramp until the last components elute from the column. Caution: NEVER exceed the upper temperature limits of your column. DO NOT exceed more than fifteen minutes at the upper isothermal temperature limit specified for the column.</p>

How to Protect Your GC Column - Part 2

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</p><p>The major focus of the symposium will be on the impact of chromatography and separation science to meet the needs of the pharmaceutical, environmental, food and health industry, as well as science and medicine. The symposium programme will reflect these themes and highlight new challenges and emerging opportunities for the science and marketing of separation and detection systems and methods.</p><p>As an integral part of the scientific programme of lectures and poster sessions, an international exhibition and vendor seminars on instrumentation and services for chromatography, separation science and mass spectrometry will be organised. ISC 2026 will provide the perfect forum for attendees from academia, industry and government research institutions for scientific exchange and networking.</p><h3><strong>ISC 2026 SYMPOSIUM KEY DATES</strong></h3><h4><strong>6-10 SEPTEMBER 2026</strong></h4><ul><li><strong>15 January 2026:</strong> Opening of Early-bird Registration &amp; Abstract submission</li><li><strong>11 March 2026: </strong>Deadline for abstract submission (orals)</li><li><strong>21 April 2026: </strong>Sending acceptance letters (orals)</li><li><strong>15 May 2026: </strong>Deadline of early-bird registration and payment &amp; Author registration deadline (orals)</li><li><strong>1 June 2026: </strong>Preliminary detailed program on web</li><li><strong>1 June 2026: </strong>Deadline for abstract submission (posters)</li><li><strong>16 June 2026: </strong>Sending acceptance letters (posters)<ul><li>Authors who submit their abstracts with a poster preference by 5 May 2026 will be notified of the outcome by 12 May 2026 and will have the opportunity to register at the early-bird rate until 15 May 2026.</li></ul></li><li><strong>30 June 2026:</strong> Author registration deadline (posters)</li><li><strong>30 July 2026:</strong> Deadline for abstract submission (late-breaking posters)<ul><li>without the possibility of competing for the Best Poster Award</li></ul></li><li><strong>11 August 2026: </strong>Sending acceptance letters (late-breaking posters)</li><li><strong>18 August 2026:</strong> Author registration deadline (late-breaking posters)</li><li><strong>25 August 2026: </strong>Deadline for late registration &amp; payment&nbsp;</li><li><strong>6-10 September 2026: </strong>Symposium</li></ul><h3><strong>REGISTRATION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register HERE for the ISC 2026</strong></a></p></blockquote><h3><strong>ABSTRACT SUBMISSION</strong></h3><blockquote><p><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Submit your Abstract HERE</strong></a></p></blockquote><h3><strong>SCIENTIFIC PROGRAM</strong></h3><h4><strong>SHORT COURSES</strong></h4><h5><strong>SC 3 Interpretation of Mass Spectra: Basic Introduction for Chromatographers</strong></h5><p><strong>🗓️ SUNDAY, 6 SEPTEMBER 2026</strong></p><p><strong>🕗 8:30 – 11:45</strong></p><p>Mass spectrometry has become an essential tool in modern liquid chromatography, yet many chromatographers receive limited formal training in mass-spectral interpretation. This introductory short course provides a practical guide to understanding and interpreting mass spectra generated by the atmospheric-pressure ionization techniques coupled with LC: electrospray ionization (ESI), atmospheric-pressure chemical ionization (APCI), and atmospheric-pressure photoionization (APPI). The course begins by outlining the information that mass spectrometry adds beyond a chromatogram and clarifying which analytical questions mass spectrometry can – and cannot – answer. Participants receive a concise refresher on mass-spectrometric fundamentals, along with an introduction to key terminology. The principles and practical consequences of ionization methods are then discussed, with emphasis on how ionization physics, LC conditions, and mobile-phase additives shape spectral appearance. Building on this foundation, the course develops practical skills for interpreting LC-ESI spectra: locating the molecular ion, determining charge state, recognizing common adducts, distinguishing in-source artefacts, and using isotope patterns to support elemental-composition hypotheses. Participants then explore how MS/MS fragmentation provides structural clues, with straightforward rules of thumb for neutral losses and class-specific fragmentation behaviors. The course concludes with an integrative exercise that synthesizes chromatographic, full-scan, and MS/MS information to support spectral interpretation. By the end, participants will be equipped with the essential skills needed to interpret LC-MS spectra effectively and to apply mass-spectrometric reasoning in routine chromatographic analysis.&nbsp;</p><h4><strong>Lecturers</strong></h4><h5><strong>Josef Cvačka</strong></h5><ul><li>Josef Cvačka is head of the Mass Spectrometry Group at the Institute of <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/62"><strong>Organic Chemistry and Biochemistry of the Czech Academy of Sciences</strong></a> and an associate professor at the Faculty of Science, Charles University in Prague. His research focuses on the structural analysis of bioactive organic compounds using advanced mass-spectrometric techniques. He develops methods for pinpointing double-bond and methyl-branching positions in lipids and aims to discover new lipid classes in biological samples. His laboratory also designs new ion sources for MS and HPLC/MS. He teaches and supervises students at Charles University and founded the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/articles?search=Czech+Museum+of+Mass+Spectrometry"><strong>Czech Museum of Mass Spectrometry</strong></a>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Josef_Cvacka_5cc8a0d1d4.jpg" alt="ISC 2026: Josef Cvačka" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Josef_Cvacka_5cc8a0d1d4.jpg 156w," sizes="100vw" width="510" height="510"></p>

ISC 2026 Short Course 3 - Interpretation of Mass Spectra: Basic Introduction for Chromatographers

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 9th February 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you technical note by <strong>Agilent Technologies, </strong>presentation by<strong> MDCW / University of Copenhagen </strong>and<strong> </strong>application notes by<strong> Shimadzu </strong>and<strong> Thermo Fisher Scientific!</strong></p><h3><strong>1. Agilent Technologies: What Causes Spots on </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=19&amp;manufacturerItems=1&amp;search=PLOT"><strong>PLOT Columns</strong></a><strong>? Will It Affect the Performance of the Column?</strong></h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/te_what_causes_spots_plot_columns_affecting_performance_5994_8775en_agilent_3b7180512a.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Spots on porous layer open tubular (PLOT) columns are caused by small voids in the stationary phase coating inside the tube. These spots are areas where there is an uneven coating or lack of phase. It is normal to find some voids in the phase coating of PLOT columns. The stationary phase in PLOT columns is an opaque, solid, and porous material. In many Agilent PLOT columns such as the GS-Alumina phases, molecular sieves, porous polymers (Q and U), and the GS-OxyPLOT, the stationary phase is visible as a white powder. For many PLOT columns, the stationary phase fill solution is a viscous suspension of particles that are less than 10 microns in diameter. The phase is coated using a dynamic process in which a plug of fill solution is pushed through the tubing, and the plug’s speed and viscosity determines the thickness of the stationary phase layer. Once the PLOT’s stationary phase is deposited, it is held in place by electrostatic charge, chemical interactions between particles, and/or binding agents. In wall‑coated open tubular (WCOT) columns, stationary phases such as polysiloxanes or polyethylene glycols are immobilized by chemical bonding to the glass surface and cross-linking between polymer strands. Because this type of bonding and cross‑linking is not possible with PLOT phases, the result is a stationary phase layer that is both fundamentally different and inherently less stable in PLOT columns than in WCOT&nbsp;columns.</p><h3><strong>2. MDCW / University of Copenhagen: One-shot tensor decomposition of full-scale GC×GC-VUV datasets for resolving petrochemical groups</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_17_Schneide_67c8ff7866.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The presentation introduces a novel <strong>all-samples-at-once, shift-invariant tri-linear tensor decomposition approach</strong> for the analysis of full-scale <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?search=GC%C3%97GC-VUV"><strong>GC×GC-VUV</strong></a><strong> datasets</strong>, aimed at resolving and quantifying petrochemical groups. Traditional template-based or pixel-based methods struggle with retention-time shifts and co-eluting compounds, often requiring manual intervention and prior chemical knowledge. The proposed approach leverages the intrinsic low-rank structure of GC×GC-VUV data to enable robust, automated group-level analysis across multiple samples simultaneously.</p><p>At the core of the method is a <strong>shift-invariant tri-linear model</strong>, conceptually related to PARAFAC and multivariate curve resolution, but extended using frequency-domain (FFT-based) modeling to explicitly account for chromatographic peak shifts. By decomposing the entire dataset in one step, the model provides <strong>accurate estimates of peak landscapes, VUV spectra, and relative peak areas</strong>, while remaining agnostic to retention-time variability. Importantly, the approach requires only a small number of tunable parameters, making it practical for routine use.</p><p>The method was demonstrated on a <strong>case study involving 14 petrochemical gas-oil samples</strong>, including straight-run, hydrotreated, hydroconverted, coker, and light cycle oils. Extracted VUV spectra showed excellent agreement with reference spectra from a VUV spectral database, enabling confident assignment of components to chemical groups such as saturates, olefins, and mono- to poly-aromatics. Quantitative results exhibited <strong>high repeatability (RSD typically 3–9%)</strong> and strong correlation with established template-based reference methods.</p><p>Overall, the work demonstrates that <strong>one-shot, shift-invariant tensor decomposition</strong> provides a powerful and scalable alternative to conventional GC×GC data-analysis strategies. By combining chemical interpretability, robustness to chromatographic shifts, and strong quantitative performance, the approach opens new opportunities for automated, high-confidence group-level analysis of complex petrochemical samples and beyond.</p><h3><strong>3. Shimadzu: Py-Screener Ver. 3: Simultaneously Test for Substances Regulated Under RoHS, TSCA, and POPs</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00949_en_4754e50164.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li>In just one analysis, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=3&amp;search=Py-Screener"><strong>Py-Screener</strong></a> Ver. 3 can determine levels of phthalate esters, brominated flame retardants (PBBs, PBDEs), PIP (3:1), UV-328, dechlorane plus (DP), short-chain chlorinated paraffins (SCCPs), and medium-chain chlorinated paraffins (MCCPs).&nbsp;</li><li>It can also test for SCCPs and MCCPs by electron ionization (EI) instead of negative chemical ionization (NCI).&nbsp;</li><li>PIP (3:1), UV-328, DP, and SCCPs and MCCPs can be screened without the need for corresponding reference materials.</li></ul><p>Countries and regulatory bodies worldwide are introducing increasingly stringent regulations on the chemical substances used in electronic devices and industrial products. The RoHS Directive and REACH regulations in the EU, the Toxic Substances Control Act (TSCA) in the USA, and the Stockholm Convention on Persistent Organic Pollutants (POPs) are also targeting an increasingly broad range of substances. Therefore, manufacturers are required to accurately identify regulated substances in their products and comply with each regulation. While Py-Screener Ver. 2 can screen for seven phthalate esters and brominated flame retardants, including substances regulated under the RoHS Directive, version 3 can also screen for PIP (3:1), which is regulated under the TSCA, as well as UV328, DP, and SCCPs and MCCPs , which are regulated under the Stockholm Convention on POPs. A list of supported substances isshown in Table 1. This article introduces the simultaneous analysis of multiple regulated substances and a case study of testing specific regulated substances in samples, using Py-Screener Ver. 3.</p><h4><strong>Analysis Process</strong></h4><p>Py-Screener Ver. 3 can determine levels of phthalate esters and brominated flame retardants contained in products in accordance with the international analytical standards IEC62321-8 and IEC62321-3-3. It can also test for specific regulated substances (Table 1) under the same conditions and in the same analysis. In this test, background intensity and instrument sensitivity (S/N) were verified before analyzing samples. These parameters are prescribed by IEC62321-8 to ensure the accuracy of the methods used. Background intensity and instrument sensitivity were determined using a reference material (PN: 225-31003- 91) *1 that consisted of a plastic sheet that was spiked with seven phthalate esters. The results met the criteria for both parameters.</p><p>The testing workflow is shown in Fig. 1. Before testing samples, calibration curves were prepared by analyzing the 1000 mg/kg phthalate ester reference material and polypropylene spiked with brominated flame retardants (ERM-EC591). A hole puncher was used to punch out two discs at a time of the phthalate ester reference material, and a cutter was used to obtain pieces of the other materials. Each material was weighed in a sample cup for analysis. During the analysis of samples, phthalate esters and some of the regulated brominated flame retardants were quantitated using a one-point calibration curve. The remaining brominated flame retardants and specific regulated substances were quantitated using the correction factor database*2 that is included with Py-Screener Ver. 3.</p><h4><strong>Conclusion</strong></h4><p>Py-Screener Ver. 3 successfully determined in samples the concentrations of the regulated substances PIP (3:1), UV-328, DP, and SCCPs and MCCPs. Normally, SCCP and MCCP levels are tested using NCI, but Py-Screener Ver. 3 uses EI. This enables it to test for not only SCCPs and MCCPs but also phthalate esters, brominated flame retardants, and other regulated substances in just one analysis. In addition, by using the relative correction factors linked to DEHP in the phthalate ester reference material, the levels of these regulated substances were determined without the need for the corresponding reference materials. Py-Screener Ver. 3 can also create a screening program that addresses substance restrictions under the RoHS Directive, the US TSCA, and the POPs Convention.</p><h3><strong>4. Thermo Fisher Scientific: Improving low carbon steel production in specialty steel processes</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/prima_pro_process_mass_spectrometer_an1626_7fc840235f.pdf"><strong>Full PDF for download</strong></a></li></ul><p>World crude steel production reached 1,691 million tonnes in 2017, up by 5.3% compared to 2016.1 While much of this capacity is still produced in primary steel processes such as basic oxygen furnaces and electric arc furnaces, the need for refined steel with greater durability and resistance to heat and corrosion has led to the increased use of vacuum degassing processes, such as VOD and RH, in secondary steel production. These processes are able to achieve ultra-low levels of residual carbon, while at the same time retaining desired levels of other alloy materials. If these processes are to achieve the required level of steel product quality, they need fast, continuous gas analysis of the furnace exhaust gas. Without accurate information on the composition of the gas leaving the furnace, any variations in the decarburization process are only detected after the event, resulting in the production of out-of-specification steel.</p><h4><strong>Advantages of mass spectrometry&nbsp;</strong></h4><p>Traditional Non-Dispersive Infra-Red (NDIR) analyzers are used in many conventional steelmaking processes to measure CO and CO<sub>2</sub> , but they can only sample at atmospheric pressure. In vacuum steelmaking the process pressure changes dramatically, typically from atmospheric pressure down to less than 1 mbar, over the 20-30 minutes of the melt. So NDIR analyzers have to sample some distance downstream from the process. Analytical data is updated several minutes after the gas leaves the melt and the control system is forced to operate on historic rather than real-time data.&nbsp;</p><p>Paramagnetic analyzers can be used to measure O<sub>2</sub> , while thermal conductivity analyzers can be used to measure H<sub>2</sub> . These analyzers also suffer from slow response, while the need to operate three different types of analyzers adds to the plant maintenance burden. Moreover, the three analyzers cannot analyze inert gases, so N<sub>2</sub> is calculated by difference, a result that suffers from the sum of the errors of the three analytical techniques.&nbsp;</p><p>Mass spectrometry operates at high vacuum so it is ideal for monitoring vacuum processes. It is also able to monitor all seven components in Table 1 in seconds rather than minutes, ensuring the plant control model is frequently updated with accurate compositional data.</p><h4><strong>Precision of analysis&nbsp;</strong></h4><p>At the heart of the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=2&amp;search=Prima+PRO+Mass+Spectrometer"><strong>Thermo Scientific™ Prima PRO Mass Spectrometer</strong></a> (MS) is a magnetic sector analyzer which offers unrivalled precision and accuracy compared with other mass spectrometers. Thermo Fisher Scientific manufactures both quadrupole and magnetic sector mass spectrometers; over thirty years of industrial experience have shown the magnetic sector based analyzer offers the best performance for industrial on-line gas analysis.&nbsp;</p><p>Key advantages of magnetic sector analyzers include improved precision, accuracy, long intervals between calibrations, and resistance to contamination. Typically, analytical precision is between 2 and 10 times better than a quadrupole analyzer, depending on the gases analyzed and complexity of the mixture.&nbsp;</p><p>A unique feature of the Prima PRO magnet is that it is laminated. Its analysis times are similar to a quadrupole analyzer, offering the unique combination of rapid analysis and high stability. This allows the rapid and extremely stable analysis of an unlimited number of user-defined gases. The scanning magnetic sector is controlled with 24-bit precision using a magnetic flux measuring device for extremely stable mass alignment.&nbsp;</p><p>The ion source is an enclosed type for high sensitivity, minimum background interference, and maximum contamination resistance. This is a high-energy (1000 eV) analyzer that offers extremely rugged performance in the presence of gases and vapors that have the potential for contaminating the analyzer. Typical performance specifications for the Prima PRO MS are shown in Table 1. Analytical performance is demonstrated by analyzing the calibration bottle over 1 hour following calibration, with an analysis time of just 6 seconds. Standard deviations measured on the calibration cylinder will be equal to or better than the stated values.</p>

News from LabRulezGCMS Library - Week 07, 2026

Article

Events

Application

Academy

Presentation

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

Phenomenex

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Separation Science

Metrohm

Agilent Technologies

Bruker

GERSTEL

Wasson-ECE Instrumentation

SciY/Mestrelab Research

Waters Corporation

<div><div><div><div><div><div><p>Discover calibration techniques to ensure accurate, reliable analytical data. This webinar covers best practices to improve precision, reproducibility, and compliance.</p></div></div></div></div></div></div><blockquote><p><strong>Presenter:</strong> John Wasson</p><p>John Wasson has over 40 years of experience in Gas Chromatography and Chemical Instrumentation. He is President of Wasson-ECE Instrumentation, Inc.</p></blockquote>

Wasson-ECE Instrumentation: Free Webinar Series

Calibration Techniques for Accurate Data

Discover calibration techniques to ensure accurate, reliable analytical data.

<div><div><div><div><div><div><p>Learn how the Single Cylinder Autosampler (SAS-100) streamlines gas sampling with automated precision, improving accuracy, consistency, and laboratory efficiency.</p></div></div></div></div></div></div><blockquote><p><strong>Presenter:</strong> John Wasson</p><p>John Wasson has over 40 years of experience in Gas Chromatography and Chemical Instrumentation. He is President of Wasson-ECE Instrumentation, Inc.</p></blockquote>

Single Cylinder Autosampler (SAS-100)

Learn how the Single Cylinder Autosampler (SAS-100) streamlines gas sampling with automated precision.

<p><strong>Sustainable Aviation Fuels (SAF) are pivotal in reducing the carbon footprint of aviation, with diverse feedstocks and production routes under active development. Fuel quality and stability must be maintained throughout the process to meet ASTM and ICAO specifications and ensure safe engine performance.</strong></p><p>This session will focus on the role of gas chromatography (GC) and liquid chromatography (LC) in assessing SAF composition. Key areas include hydrocarbon profiling, measurement of aromatics, and detection of oxygenates such as FAME that influence fuel behavior. Case examples will show how analytical workflows support feedstock evaluation, refining optimization, and blend certification.</p><p>By linking analytical control to performance and safety, the session demonstrates how chromatography ensures SAF meets the stringent requirements of aviation applications.</p><blockquote><p><strong>Presenter:&nbsp;</strong> Naoto Hashikita (Product Specialist, Agilent Technologies, Japan)</p><p>Naoto joined Agilent in 2018 as a technical sales specialist specializing in GC and GC/MS. He holds a master’s degree from the University of Tokyo in the field of fuel cells. He has supported customers in the energy and chemical industries, with a focus on promoting green analytical solutions. His motto is: "Contributing to a carbon-neutral society through analytical instruments."</p></blockquote>

Agilent Technologies: Energy Transition Webinar Series

Sustainable Aviation Fuels: Path to Greener Skies

Webinar on Agilent GC/LC for Sustainable Aviation Fuels—analyze composition, certify blends, and ensure compliance with ASTM and ICAO standards.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Urban snow is an efficient scavenger of atmospheric contaminants—from polycyclic aromatic hydrocarbons (PAHs) generated by traffic emissions, to microplastics and associated additives from tyre wear. In Arctic cities such as Tromsø, Norway, large volumes of this contaminated snow are dumped into the sea each year, yet the environmental impacts remain poorly understood.</strong></p><p>In this webinar, Dr Cleo Davie-Martin (NILU, Norway) will present findings from the DUMP project (Direct analysis of Urban snow particulates for traffic-related microplastic additives and polycyclic aromatic hydrocarbons), which developed a solvent free, direct thermal desorption (TD) GC-MS approach for analysing particulates in snow, eliminating toxic solvents and reducing sample prep time. Cleo will discuss method optimization, including the use of analyte protectants and desorption aids to improve sensitivity, showing how PAH concentrations vary with traffic intensity.</p><p>Caroline Widdowson (Markes International) will showcase a novel TD–GC–MS methodology to track microplastics through all stages of a wastewater treatment plant, achieving large sample sizes, high reproducibility, and greater system robustness compared with traditional Py-GC-MS.</p><p>Together, these studies highlight how TD–GC–MS can streamline the analysis of complex particulate matrices, reduce environmental impact, and open up new opportunities for environmental monitoring and microplastic research.</p><h5><strong>By attending this webinar, you will learn:</strong></h5><ul><li>Direct TD–GC–MS can reduce sample preparation time and avoid toxic solvents.</li><li>Analyte protectants and desorption aids improve sensitivity and reproducibility.</li><li>The technique is applied to real-world challenges, from Arctic snow to microplastics in food and environmental samples.</li></ul><blockquote><p><strong>Presenter: </strong>Cleo Davie-Martin (Senior scientist, NILU)</p><p>Dr Cleo Davie-Martin is a senior scientist at NILU in Tromsø, Norway. She holds a PhD in Environmental and Analytical Chemistry from the University of Otago, where she studied volatilization processes affecting the distribution of semi-volatile organic contaminants (SVOCs). Her research spans bioremediation of PAHs, biogenic VOC emissions from the Arctic tundra and marine environments, and environmental monitoring of pollutants. Cleo has extensive experience in analytical method development and quantification across diverse contaminant classes and environmental matrices, working with techniques such as thermal desorption (TD), gas chromatography–mass spectrometry (GC-MS), and proton-transfer-reaction mass spectrometry (PTR-MS). At NILU, she also contributes to the digitalization and management of environmental monitoring data.</p><p><strong>Presenter:&nbsp;</strong>Caroline Widdowson (Material Emissions Specialist, Markes International)</p><p>Caroline works for Markes International, an advanced analytical instrument manufacturer. Having completed her chemistry degree at Cardiff University, she followed on with a Ph.D. in Organic Chemistry then an MBA. As part of her current role, Caroline advises manufacturers, test laboratories, and research institutes on equipment needed to monitor interior environments and study chemical emissions from materials. Caroline is the Chair of the UK BSi committee developing standard methods for the sampling and analysis of chemicals from products and materials (BSi EH2/5); she also participates in ISO, ASTM, and CEN standards and national regulatory committees relating to this area.</p></blockquote></div></div></div>

SeparationScience: Snow DUMP-ing: Using Direct TD–GC–MS to Tackle Urban Snow and Microplastic Pollution

Snow DUMP-ing: Using Direct TD–GC–MS to Tackle Urban Snow and Microplastic Pollution

Discover how TD–GC–MS simplifies complex particulate analysis, cuts environmental impact, and advances microplastic and environmental research.

TD–GC–MS to Tackle Urban Snow and Microplastic Pollution

<div><p><strong>Join our webinar for a quick and application-focused guide to FT-IR based gas analysis. Discover how our FT-IR solutions deliver precise, real-time, and calibration-free quantification of gas compounds in gas mixtures with real-world application examples.</strong></p><h4><strong>What You’ll Learn</strong></h4><ul><li>Basic workflow for FT-IR based gas analysis measurements and commonly used setups</li><li>Definition of quantification methods for real-time, calibration-free quantification of gas compounds in gas mixtures</li><li>Real world application examples:&nbsp;<ul><li>Quality control of calibration gases</li><li>Catalytic conversion of CO to CO₂</li><li>Exhaust gas analysis under real driving conditions</li></ul></li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Researcher in the field of catalytic reactions</li><li>Environmental scientists</li><li>Process engineers</li><li>Analytical chemists</li><li>Quality control professionals</li><li>Anyone interested in gas analysis techniques</li></ul><blockquote><p><strong>Presenter:</strong> Dr. Stephan Berner (Application Manager Gas Analytics)</p><p>Stephan Berner is Bruker’s global expert for FT-IR-based gas analysis.</p></blockquote></div>

Bruker: A Guide to FT-IR-based Gas Analysis

A Guide to FT-IR-based Gas Analysis

Join our webinar for a quick and application-focused guide to FT-IR based gas analysis.

<h4><strong>Analysis of Innovative Fermentation Aromas</strong></h4><h5><strong>From acid whey to microalgae – exploring new paths in aroma analysis</strong></h5><p>How can natural aromas from fermented products be precisely characterized?</p><p>In this webinar, Dr. Marina Rigling from the University of Hohenheim demonstrates how modern sorptive extraction techniques such as HS-SPME, HS-SBSE, and DI-SBSE provide new insights into complex matrices.</p><p>Through practical examples – from vegan cheese flavors and basil off-notes to fermented microalgae – you’ll learn how to identify, compare, and evaluate sensory-active compounds.</p><p>Machine learning also plays a role: helping to optimize analytical parameters and improve data interpretation.</p><p>👉 Experience how innovative fermentation processes and advanced aroma analysis come together – for more flavor, more knowledge, and new perspectives in research.</p><ul><li><strong>Duration:</strong> approx. 45 minutes</li><li><strong>Language:</strong> English</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Marina Rigling, University of Hohenheim</p></blockquote>

GERSTEL: Innovative Fermentation Aroma Analysis using HS- and DI-SBSE as well as HS-SPME

Innovative Fermentation Aroma Analysis using HS- and DI-SBSE as well as HS-SPME

In this webinar, Dr. Marina Rigling demonstrates how modern HS-SPME, HS-SBSE, and DI-SBSE provide new insights into complex matrices.

Fermentation Aroma Analysis by HS-, DI-SBSE, HS-SPME

<p><strong>Carrier gas is a necessary component to any functioning gas chromatographic system. The rising cost of helium, due to a global shortage in supply, has forced labs to consider alternatives such as hydrogen or even nitrogen, but is this a smart choice? Does it make sense for your laboratory? What are the common pitfalls or issues that might arise? In this talk we will take out some of the guesswork associated with making this important decision and help you decide if the switch is right for you.</strong></p><blockquote><p><strong>Presenter: </strong>Mark Sinnott (Application Engineer, Agilent Technologies, Inc.)</p><p>Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Twin Falls Idaho.</p></blockquote>

Agilent Technologies: Becoming a Better Chromatographer - Educational Webinar Series

Carrier Gas Conundrum: Smart Solutions for Helium Alternatives

Discover if switching from helium to hydrogen or nitrogen as a GC carrier gas is right for your lab.

Carrier Gas Solutions for Helium Alternatives

<div><p><strong>Risk is no longer a static concept—it’s dynamic, data-driven, and deeply tied to how organizations manage information across systems, teams, and workflows. In regulated industries, the ability to analyze, mitigate, and monitor risk effectively is essential for ensuring patient safety, product quality, and operational continuity.</strong></p><p>In this session, we will explore how modern data governance practices can help organizations proactively identify risks, implement targeted mitigation strategies, and establish vigilant monitoring to support compliance and resilience.</p><h5><strong>Attendees will gain practical insights into:</strong></h5><ul><li>Conducting meaningful risk analysis across data and operational domains</li><li>Designing mitigation strategies that align with CGMP and QMM expectations</li><li>Building monitoring frameworks that detect issues before they escalate</li><li>Equipping teams with the tools and mindset to think critically and respond effectively in high-risk environments</li></ul><p>Whether you're upgrading and implementing new systems or refining your compliance strategy, this session will provide actionable guidance to help you strengthen your risk posture and elevate your data governance maturity.</p><blockquote><p><strong>Presenter:</strong> Tracy Hibbs (Principal Consulting Product and Marketing Manager, Waters Corp.)</p><p>Tracy has worked for Waters Corporation since 1999 and has held a variety of positions including Technical Trainer, Business Impact Consultant, Training Manager for Informatics and Data Integrity, and currently, Principal Consulting Marketing Manager focusing on Informatics solutions. Tracy provides support for Waters Empower Software Suite and is concentrated on developing laboratory data management software solutions that help organizations achieve their scientific and operational objectives in regulated environments. Prior to joining Waters, Tracy was a Research Scientist where she gained experience in chromatography and the associated data systems.​</p></blockquote></div>

Waters Corporation: Analysis, Mitigation, and Monitoring in Modern Data Governance

Analysis, Mitigation, and Monitoring in Modern Data Governance

Learn how data governance strengthens risk analysis, mitigation, monitoring to enhance compliance, safety, and operational resilience in regulated industries.

Analysis, Mitigation, and Monitoring in Data Governance

<p><strong>Handheld Raman spectroscopy is a proven tool for quick, non-destructive analysis of chemicals and raw materials. While most devices can easily measure through simple transparent or translucent packaging, they often struggle with opaque, multi-layer containers – common in warehouses or emergency response to hazardous materials.</strong></p><p>This webinar will showcase how advanced through-container Raman systems overcome these limitations. By integrating specialized optical hardware with software algorithms, these instruments can obtain a true Raman spectrum from materials hidden behind multiple layers of opaque packaging, providing accurate identification without opening the container.</p><p>An interactive question-and-answer session with the presenter will follow our presentation.</p><h4><strong>Key Takeaways:</strong></h4><ul><li>Learn how hardware and software innovations enable sample identification through opaque and highly colored containers.</li><li>Application examples demonstrating enhanced workflow efficiency and operator safety in handling chemicals and raw materials, from the loading dock to the process line.</li><li>Practical considerations for implementing these methods, including container variability, signal optimization, and method validation.</li></ul><h4><strong>Who should attend?</strong></h4><ul><li>QA/QC chemists, first responders and hazmat professionals, method development and analytical scientists, process engineers, anyone responsible for chemical identification or incident assessment</li></ul><blockquote><p><strong>Presenter: </strong>Britan Stringer (Product Specialist Raman Spectroscopy, Metrohm Spectro)</p><p>Britan Stringer joined Metrohm in 2019 and is currently based at Metrohm Spectro’s Laramie, WY facility. Her work emphasizes practical, field- and lab-based Raman for rapid identification and verification across the pharmaceuticals, chemicals, and defense &amp; security. With a B.S. in Chemical Engineering, Britan aligns method design, documentation, and user enablement to deliver reproducible results from warehouse receipt to mission-critical field use.</p></blockquote>

Metrohm: Through-container Raman for chemicals, raw materials, and field response

Through-container Raman for chemicals, raw materials, and field response

Learn how through-container Raman technology identifies chemicals through opaque packaging, improving safety and workflow efficiency. Live webinar by Metrohm.

Through-container Raman for chemicals, raw materials

<p><strong>Content uniformity and assay are critical quality attributes for solid oral dosage forms, yet traditional wet chemistry methods are time consuming and destructive. In this webinar, we’ll showcase the automated SciYbotic Tablet Testing (TT) system that enables faster, more accurate non-destructive testing for tablet release.</strong></p><p>The system showcases a fully automated workflow for tablet quality testing that integrates robotic handling, 3D vision, and spectroscopic analysis with the Bruker Multi Purpose Analyzer (MPA) to eliminate manual variability and enhance precision. By aligning with Process Analytical Technology (PAT) and Pharma 4.0 goals, the SciYbotic TT enables real-time predictions of API content. It supports efficient, compliant tablet release, demonstrating the transformative impact of automation in pharmaceutical manufacturing.</p><h4><strong>Learning Points</strong></h4><ul><li>You’ll discover how the SciYbotic Tablet Testing (TT) system enables non-destructive, real-time analysis of content uniformity and assay.&nbsp;</li><li>Explore the integration of robotic handling, 3D vision, and spectroscopic analysis by Bruker MPA in a fully automated workflow.&nbsp;</li><li>Learn how the system aligns with PAT and Pharma 4.0 initiatives.&nbsp;</li><li>See how automation enhances precision, compliance, and efficiency in tablet release processes.&nbsp;</li></ul><h4><strong>Who should attend</strong></h4><ul><li>Oral Solid Dose (OSD) manufacturing professionals seeking to modernize quality control.&nbsp;</li><li>Quality assurance and quality control specialists focused on improving tablet release workflows.&nbsp;</li><li>Senior managers, process engineers and automation leads exploring Pharma 4.0 solutions and technology transfer.&nbsp;</li><li>PAT and advanced control strategy experts and leaders.&nbsp;</li></ul><blockquote><p><strong>Presenter:</strong> Andrew Anderson (Consultant)</p><p>Andrew Anderson is a strategic pharma leader with extensive expertise in small molecule development and advanced analytical technologies. At GSK and Johnson &amp; Johnson, he led the technology strategy, roadmaps, automation, and Process Analytical Technology (PAT) across R&amp;D and commercial operations. Recognized for forging impactful government, academic, and cross-pharma partnerships, Andrew promotes innovation through cross-functional leadership and comprehensive tech implementation, delivering measurable improvements in efficiency, data integrity, and resource optimization.</p><p><strong>Presenter: </strong>Matt Jones (Account Manager, SciY)</p><p>Matt Jones is a seasoned automation specialist with over 20 years of experience delivering engineered solutions across highly regulated sectors, including pharmaceuticals, biotechnology, and advanced manufacturing. His work frequently involves the application of process analytical technology (PAT) within custom automation systems designed to meet stringent industry standards.<br>With a strong foundation in vision systems and robotics engineering, Matt has deep expertise in machine integration, control architecture, and data-driven process optimization. He excels at translating complex requirements into scalable, compliant automation platforms that enhance throughput, quality, and traceability.</p><p><strong>Presenter: </strong>Holger Lutz (Business Unit Manager Chemistry, Pharma &amp; Process Applied Spectroscopy - Bruker Optics GmbH &amp; Co. KG)</p><p>PhD in Chemistry at University of Karlsruhe, Germany, focus on Analytical Chemistry. Starting 2002 as a NIR sales person at Bruker Optics. In 2007, took over the sales responsibility of PAT solutions in Germany. In parallel, built up a global sales and support infrastructure for PAT. Since 2018, is business unit manager of the newly created business unit “Chemistry, Pharma &amp; Process”. In this function, is involved in the product management of the new PAT analyzers and related software, supports the global sales &amp; application team, and is the main contact for Key Accounts.</p></blockquote>

SciY: Tablet Release Reinvented: Robotics, Vision, and Spectral Intelligence

Tablet Release Reinvented: Robotics, Vision, and Spectral Intelligence

Learn how automated robotic, vision, and spectroscopic workflows streamline non-destructive tablet testing, compliance, and Pharma 4.0 readiness.

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