Join us for a free two-day LECO Separation Science Workshop on September 23–24, 2026, at the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/219">C³AL Laboratory</a> at Cal State LA. Registration is free, and meals and refreshments will be provided throughout the workshop.&nbsp;<h4>Registration</h4><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=iYeNbqIuykW7qZP4_jUEVbznDB40eK1PgjPzhHyb__9URTFTTFA5UEEzQ1A4MUtFV0o4TEJTNlZCOS4u&amp;route=shorturl">Register HERE</a>Space is limited, register today!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg" alt="LECO: LECO Separation Science Workshop - QR code for registration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg 156w," sizes="100vw" width="437" height="437"></blockquote><h4>Hand-on Experience with the LECO Complex Chemical Composition Analysis Lab C3AL</h4><ul><li>Work directly with LECO instruments in the C3AL Laboratory</li><li>Learn complete analytical workflows from sample to answer</li><li>Get expert guidance from LECO application scientists</li><li>Develop methods and solve real-world challenges</li><li>Collaborate, ask questions, and build your skills</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg" alt="Cal State LA: The LECO Pegasus BTX system in Cal State LA’s LECO Complex Chemical Compositional Analysis Lab enhances research and student training in advanced chemical analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg 227w," sizes="100vw" width="1252" height="863">The first day will focus on the fundamentals and theory of comprehensive two-dimensional gas chromatography (GC×GC), with an emphasis on understanding how GC×GC can enhance your research, solve complex analytical challenges, and support your laboratory or company goals.&nbsp;The second day will be dedicated to hands-on activities, giving participants the opportunity to work directly with LECO instrumentation, learn practical analytical workflows, and analyze their own samples with guidance from LECO application scientists.&nbsp;Whether you are new to GC×GC or looking to expand its use in your research or organization, this workshop offers a unique opportunity to learn, explore, and apply the technology in a practical setting. Space is limited, so register early!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg" alt="Cal State LA: LECO QUADJET GCxGC coupled to Pegasus BT 4D TOM MS in the Complex Chemical Composition Analysis Lab (C³AL)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/thumbnail_Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg 234w," sizes="100vw" width="1949" height="1299">

LECO Separation Science Workshop

An international research team, which included scientists from the Faculty of Science at Palacký University and the Institute of Physics of the Czech Academy of Sciences, has succeeded in unraveling the complex mechanism by which a chemical bond is formed during a collision between molecules. The experts found that the reaction only takes place if the molecules are oriented towards each other within a very narrow range of angles – within the so-called cone of reaction. This joint research has thus provided an answer to one of the fundamental questions of chemistry: under what conditions do chemical bonds form between molecules. The results of the study&nbsp;Spatially resolving the cone of reaction for a single molecule&nbsp;were published in the prestigious scientific journal&nbsp;Science.Many chemical reactions begin with the collision of two particles. However, for a new chemical bond to form, it is not enough for the molecules simply to come into contact. Their collision must occur with sufficient energy, in the correct relative orientation and at the right location. Under normal conditions, such as in solutions or gases, molecules collide chaotically, and the precise parameters of these collisions cannot therefore be controlled.<h4>Molecules under control</h4>Scientists were able to control the collisions of individual molecules on a copper surface and monitored the process using a scanning tunnelling microscope. They used the instrument not only to visualise individual molecules, but also to deliberately accelerate the reactants towards one another. They subsequently analysed each collision with atomic-level resolution. This enabled them to determine unequivocally whether a new chemical bond had formed between the molecules.<h5>“What is hidden in the statistics of billions of collisions in conventional chemistry, we have managed to break down into individual cases and map directly.” Adam Matěj</h5>A key finding of the study is that the outcome of a collision is determined by the extremely precise orientation of the molecules. A new bond was formed only when the target molecule was oriented within a few degrees of the direction of movement of the other molecule. When rotated by more than fifteen degrees, the molecules simply bounced off each other without any reaction.<h4>The precise orientation of the molecules is crucial</h4>“For the first time, we were able to observe, using a single molecule, exactly how precisely it must be oriented for the reaction to take place at all. What is hidden in the statistics of billions of collisions in conventional chemistry, we have managed to break down into individual cases and map directly,” said Adam Matěj from the Department of Physical Chemistry at the Faculty of Science.The theoretical part of the study, in which researchers from Palacký University and the Institute of Physics of the Czech Academy of Sciences were involved, played a significant role. Using quantum-mechanical calculations, they explained why the ‘reaction cone’ is so narrow. It turned out that the reactive carbon atom is surrounded by hydrogen atoms, which block the access of the reacting molecule from almost all directions.<h4>The arrangement of atoms restricts access to the reaction</h4>The calculations also shed light on a surprising experimental result. The chemical reaction took place even when the molecule moved along an adjacent row of copper atoms, where, according to the original assumptions, no bond should have formed.<h5>“The strength of this work lies in the fact that the experiment and theory have been brought together into a single picture. The microscope showed what happens during the collision, and the calculations explained why.” Pavel Jelínek</h5>“The explanation lies in the slight displacement of a single copper atom on the surface. The target’s bond to the surface pulls it out of its position and brings it close enough to the neighbouring row that it can literally take over the projectile and direct it to the correct spot. This shows that the surface is not merely a passive substrate, but actively participates in the reaction itself and can even facilitate pathways that would otherwise be unfavourable,” noted Adam Matěj.<h4>The surface also determines the course of the reaction</h4>The results are significant for the development of so-called surface reactions, in which new materials and nanostructures are purposefully assembled from individual molecules. A better understanding of the influence of the spatial arrangement of molecules will enable the design of molecular building blocks so that they bond more reliably and efficiently. This represents an important step towards the development of technologies based on the controlled construction of structures atom by atom.“The strength of this work lies in the fact that experiment and theory have been brought together into a single picture. The microscope showed what happens during the collision, and the calculations explained why. Without a theoretical model, we would have found it difficult to discover that the movement of a single surface atom is behind the unexpected course of the reaction,” added Pavel Jelínek from the Institute of Physics of the Czech Academy of Sciences.<blockquote>The study&nbsp;Spatially resolving the cone of reaction for a single molecule&nbsp;was produced in collaboration between researchers from the University of Graz, the Institute of Physics of the Czech Academy of Sciences, Palacký University in Olomouc, Charles University and Humboldt University in Berlin.</blockquote>

Scientists reveal when chemical bonds form in molecular collisions 

Injecting water into a gas chromatography (GC) system has always raised concerns for analysts. Many wonder if water will damage their <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products?category=7&amp;manufacturerItems=50">GC column</a> or instrument. In fact, one of the most common questions in gas chromatography water analysis is whether aqueous samples can be safely introduced without compromising results.Selecting the right GC column for water analysis and following proper injection techniques can minimize the risk of column damage and maintain reliable analytical results.<h3>Why Water Injections Are Risky in GC</h3>Water injections in gas chromatography columns are risky due to the following reasons:<h4>Backflash Issues</h4>Water expands significantly when vaporized at high inlet temperatures (e.g., 250–300 °C). If the expansion volume exceeds the inlet liner capacity, backflash can occur. This contaminates injector parts, leaving residues that cause ghost peaks, carryover, sample loss, and elevated baselines, ultimately reducing reproducibility and accuracy.<h4>Stationary Phase Degradation</h4>As a highly polar solvent, water can hydrogen bond with stationary phase polymers such as polyethylene glycol (PEG) or wax phases. Repeated exposure alters selectivity, shifts retention times, and may increase bleed in non-crosslinked phases. While older immobilized PEG phases are especially vulnerable, modern chemically bonded and crosslinked stationary phases offer improved resistance, making them more suitable to inject up to 100% water samples.<h4>Incomplete Vaporization</h4>Water’s high boiling point and poor wetting of non-polar stationary phases can result in incomplete vaporization. This may lead to peak splitting, band broadening, or reduced sensitivity. For this reason, injection settings need to be finely adjusted to avoid these effects.<h4>Detector Issue</h4>Standard GC detectors do not directly detect water. Excess water injected into a flame ionization detector (FID) can quench or even extinguish the flame, while moisture in an electron capture detector (ECD) can interfere with electron capture efficiency, suppressing signals or causing false responses.<h3>Choosing the Right GC Columns for Water-Containing Samples</h3>Here are some strategies that can help you increase the life of GC columns when analyzing water-containing samples.<ul><li>Use of cross-linked phases: Modern stationary phase design has greatly improved tolerance to water injections in GC. Cross-linking chemically bonds the stationary phase to the silica surface, making it far more resistant to leaching or washout from polar solvents. Traditionally immobilized but not cross-linked phases were much more vulnerable to degradation. For example, polyethylene glycol (PEG) phases are inherently hydrophilic and prone to water damage unless cross-linked. With technologies such as engineered self-crosslinking (ESC), used in Phenomenex <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1571">Zebron ZB-WAXplus GC columns</a>, PEG phases can withstand repeated water injections without significant loss of efficiency.</li><li>Use of non-polar columns: Non-polar bonded and cross-linked columns (e.g., PDMS phases) are inherently resistant to water damage, though incomplete vaporization may still affect peak quality.</li></ul><h3>Tips to Protect Your GC System from Water Damage</h3>Implementing a few key tips can help protect your GC system from water damage. Here are some of the important recommendations:<ul><li>Keep injections small: Limit water injections to ≤0.2 µL to minimize backflash and protect the stationary phase.</li><li>Select the right liner: Use an appropriately sized inlet liner (e.g., 4.0 mm ID tapered or with a double gooseneck) to reduce backflash. A deactivated glass wool plug can promote rapid vaporization, though it may not be suitable for all analytes.</li><li>Reduce syringe carryover: Rinse syringes with a 50:50 methanol–water mixture between injections. In some methods, preparing samples with a small percentage of methanol can improve reproducibility and syringe performance.</li><li>Optimize solvent and injector conditions: Limit water injections to ≤0.2 µL to minimize backflash and protect the stationary phase.</li><li>Adjust carrier gas conditions: Ensure your <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/5538">gas chromatography injector setup</a> is correct to prevent water buildup. Combining water with a lower-expansion solvent (e.g., methanol) and maintaining an optimized injector temperature helps improve vaporization while limiting expansion.</li><li>Maintain a clean carrier gas supply: Replace gas cylinders before they are nearly empty to avoid backflow or moisture intrusion into the system While injecting water into a GC system is not simple and ideal, it can be managed safely with the right precautions. By choosing the appropriate stationary phase, following proper GC injector setup, and maintaining your instrument, you can conduct gas chromatography water analysis with confidence. For more information on GC hardware and maintenance, explore the <a target="_blank" rel="noopener noreferrer" href="https://www.phenomenex.com/resources/knowledge-center/gc-knowledge-center/understanding-the-essential-components-of-gas-chromatography">key parts of a GC instrument</a>.</li></ul>

Water Injections in GC: Is it Safe?

Article

Events

Academy

Science and research

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

Phenomenex

In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

LECO

Palacký University Olomouc (UP) is an internationally respected and scientifically and academically highly productive university in Central Europe. Founded 22 December 1573, it is the second-oldest university in the Czech Republic and the oldest one in Moravia. For 450 years it has contributed to the intellectual wealth of society and to its scientific, cultural, and social development.

Palacký University Olomouc

Separation Science

Gulf Bio Analytical Group

SepSolve Analytical

SelectScience

Join SepSolve Analytical as they demonstrate how the latest advances in GC×GC hardware and software are extending the capabilities of the technique from the niche to the mainstream.
Flow modulation of the gas stream overcomes the practical difficulties of applying GC×GC for routine analyses and has reduced cost of ownership. Easy-to-use chemometrics tools make life easier by preventing data processing becoming the bottleneck of analytical workflows.
In this presentation, we’ll cover some fascinating examples of real-life applications that have benefited from the separating power of GC×GC, in both research and routine laboratories. These include biomarker discovery, aroma profiling and environmental monitoring:
<ul>
<li>Total petroleum hydrocarbons (TPH) – Robust and routine monitoring of total petroleum hydrocarbons (TPH) in environmental matrices using GC×GC-FID.
</li>
<li>Chemical fingerprinting of pyrolysis oils – Detailed characterisation of pyrolysis oils from solid waste plastics using GC×GC–TOF MS to identify possible contaminants, and help to refine process design.
</li>
<li>Biomarker discovery – Thermal desorption coupled with GC×GC–TOF MS to capture comprehensive breath profiles and uncover potential biomarkers of disease.
</li>
<li>Aroma profiling – Comparison of whisky aroma profiles by SPME–GC×GC–TOF MS to distinguish between whiskies from different regions and evaluate the impact of maturation.
</li>
</ul>
By attending this presentation you will:
<ul>
<li>Learn the basics of GC×GC and what it offers over and above standard GC
</li>
<li>Debunk the myths of GC×GC being a ‘research-only’ tool
</li>
<li>See how cutting-edge software tools can simplify everyday use of GC×GC
</li>
<li>Familiarise yourself with the latest GC×GC applications
</li>
</ul>
Who should attend:
<ul>
<li>GC and GC-MS users who want to enhance their ability to analyse complex samples
</li>
<li>Separation scientists who want to find out more about GC×GC
</li>
<li>GC×GC practitioners wanting to further their knowledge on recent advances in applications, hardware and software
</li>
</ul>
<blockquote>
Presenter: Laura McGregor (Product Marketing Manager, SepSolve Analytical)
</blockquote>
<blockquote>
Laura McGregor received an M.Chem. in chemistry from the University of St Andrews, UK, followed by an M.Sc. in forensic science at the University of Strathclyde, UK. Her Ph.D. in environmental forensics, also at the University of Strathclyde, sparked her interest in GC×GC and she has been a strong advocate of the technique ever since. In her current role as Product Marketing Manager at SepSolve Analytical, she continues to apply GC×GC–TOF MS to challenging applications.
</blockquote>

Separation Science: Demystifying comprehensive two-dimensional gas chromatography (GC×GC)

Demystifying comprehensive two-dimensional gas chromatography (GC×GC)

Examples of real-life applications that have benefited from the separating power of GC×GC, in both research and routine laboratories.

Comprehensive two-dimensional gas chromatography (GC×GC)

In the ever-evolving landscape of today&#39;s competitive market, the significance of maintaining the quality and safeguarding the integrity of your brands cannot be overstated.
It is becoming even more imperative to outpace your competitors by leveraging powerful technology which can enhance your workflows, elevate brand quality and empower your Aroma, Flavour and Fragrance analysis.
In this webinar, we explore the capabilities of LECO technology and the impact it is having on overcoming the challenges faced in the Aroma, Flavor, and Fragrance industry.
<h4>1. Enhanced Workflows for Essential Oils: Increase Confidence in QC Screening &amp; Characterisation</h4>
<ul>
<li>Presented by Sebastiano Panto
</li>
<li>Hydrogen Carrier Gas
</li>
<li>BT 1D GC-TOFMS
</li>
<li>Maximise efficiency with Sync Software
</li>
</ul>
<h4>2. Investigate Perfumes in Greater Depth &amp; Faster: Utilise GCxGC to characterise perfume complexity and understand important differences for both performance and quality assurance</h4>
<ul>
<li>Presented by Lena Dubois
</li>
<li>Unveiling the power of BT4D and GCxGC-TOFMS
</li>
<li>Distinguishing real from counterfeit perfumes
</li>
<li>Seamlessly navigate complexity with Tile Software
</li>
<li>Allergen analysis to ensure safety
</li>
</ul>
<h4>3. Non-Target Characterization and Simultaneous Quantitation for Reformulation of Complex Fragrance Samples with GCxGC-MS/FID</h4>
<ul>
<li>Presented by Dr. Liz Humston-Fuller
</li>
<li>Mastering BT4D, RFF, Splitter/FID technologies
</li>
<li>Characterisation in detail
</li>
<li>Confident quantification through enhanced FOD accuracy
</li>
</ul>
<h4>4. Whisky Analysis: Unravel the complexities and differences of Whiskies</h4>
<ul>
<li>Presented by Taff Morgan (The Open University)
</li>
<li>BT 1D/BT4D
</li>
<li>Complex characterisation
</li>
<li>Comparison of different origins and process types
</li>
<li>Fast interpretation of large sample sets with Sync/Tile
</li>
</ul>
By immersing yourself in these advanced technologies and software solutions, you stand to revolutionize your workflow, elevate quality control measures, protect your supply chain, uphold brand reputation, ensure product safety, and shape consumer perception.
<blockquote>
Presenter: (Alan Griffiths, Director of Separation Science Global Sales, LECO USA)
</blockquote>
<blockquote>
Initially joining LECO UK as an installation and service engineer 15 years ago before taking on the challenges of sales across the UK and Ireland territory, Alan has a vast experience and understanding of LECO’s separation science portfolio. In the webinar, Alan will both introduce the speakers and chair the Q&amp;A.
</blockquote>
<blockquote>
Presenter: (Dr. Liz Humston-Fuller, Applications Chemist, LECO USA)
</blockquote>
<blockquote>
Liz earned her PhD in Analytical Chemistry with Prof Robert Synovec in the group that developed the tile-based Fischer ratio algorithms that have been further developed in collaboration with LECO to underpin ChromaTOF Tile. Her presentation will introduce “Advanced processing software with ChromaTOF Tile &amp; ChromaTOF Sync.”
</blockquote>
<blockquote>
Presenter: (Dr. Lena Dubois, Applications Chemist, LECO Europe)
</blockquote>
<blockquote>
Lena has ten years’ experience in the field of application chemistry and gained her PhD under the mentorship of Prof. Jef Focant at Liège University. Lena will be discussing “Workflows for the assessment of key aroma compounds” by utilising the latest in advanced GC and GCxGC -TOFMS and data processing technologies.
</blockquote>
<blockquote>
Presenter: (Dr. Geraint (Taff) Morgan, Department of Physical Sciences, The Open University)
</blockquote>
<blockquote>
Taff is an analytical chemist with vast experience, applying his knowledge from the bottom of the ocean to the surface of a comet. His talk entitled “Comprehensive Evaluation of Scotch Whisky Aroma Profile Using SPME-GCxGC-TOFMS” will demonstrate the effective use of high-quality instrumentation and software to real world whisky samples.
</blockquote>

LECO: State of the Art Technology for Aroma, Flavour and Fragrance Analysis

State of the Art Technology for Aroma, Flavour and Fragrance Analysis

Explore the capabilities of LECO technology and the impact it is having on overcoming the challenges faced in the Aroma, Flavor, and Fragrance industry.

Technology for Aroma, Flavour and Fragrance Analysis

Discover the cutting-edge workflow for the analysis of Mineral Oil Saturated Hydrocarbons (MOSH) and Mineral Oil Aromatic Hydrocarbons (MOAH) using GC×GC-TOFMS/FID.
Join our exclusive webinar where we will delve into the exciting advancements in analytical technology that are revolutionizing the way we identify and characterize these crucial components.
What To Expect:
<h4>GC×GC-TOFMS: Unraveling The Mysteries Of MOH</h4>
<ul>
<li>Learn how to set up a robust classification method using GC×GC-TOFMS and the MOH-mix, enabling precise and reliable analysis
</li>
<li>Witness the power of the classification method as we apply it to real samples, gaining valuable insights into various matrices
</li>
<li>Explore the market substances in mineral oils and understand how they aid in verifying and characterizing the contamination source
</li>
<li>Unravel the complexity of the MOAH fraction as we demonstrate the separation and identification of different ring systems, as discussed in the “Draft opinion update risk assessment of MOH in food for public consultation” by the European Food Safety Authority
</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Figure_1_Schematic_view_of_the_GC_GC_TOFMS_FID_instrument_setup_b6949cc782/LECO-Figure-1-Schematic-view-of-the-GCGC-TOFMS-FID-instrument-setup.jpg" alt="LECO: Obrázek 1: Schematic view of the GC×GC-TOFMS-FID instrument setup"/>
<h4>GC×GC-FID: Expanding Possibilities For Mineral Oil Analysis</h4>
<ul>
<li>Discover the seamless hardware setup for aligning GC×GC-TOFMS and GC×GC-FID signals, combining the strengths of both technologies
</li>
<li>Explore our state-of-the-art software tool for quantifying MOSH and MOAH fraction with GC×GC-FID, which can be implemented for accurate verification of SCoPAFF values
</li>
<li>Dive into the capabilities of our innovative software tool for quantifying different ring systems within the MOAH fraction, enhancing the depth of your analysis
</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Figure_2_GC_GC_contour_plot_of_LECO_s_MOH_mix_which_is_used_to_setup_the_classification_method_within_the_Chroma_TOF_software_44db161d98/LECO-Figure-2-GCGC-contour-plot-of-LECO's-MOH-mix-which-is-used-to-setup-the-classification-method-within-the-ChromaTOF(r)-software.jpg" alt="LECO: Obrázek 2: GC×GC contour plot of LECO’s MOH mix which is used to setup the classification method within the ChromaTOF® software"/>
Why Attend:
<ul>
<li>This webinar is a must-attend for scientists, researchers, and professionals in the field of analytical chemistry and food safety. Gain a deeper understanding of the latest techniques and technologies used in MOSH/MOAH analysis, equipping you with the knowledge to elevate your research and ensure compliance with industry standards.</li>
</ul>
<blockquote>
 Presenter: Sebastiano Panto (LECO Europe B.V., Head of Separation Science Applications Europe)
</blockquote>
<blockquote>
Presenter: Stefan Vinnenberg (LECO Instrumente GmbH, Account Manager DACH &amp; BeNeLux – Separation Science)
</blockquote>

LECO: Unlock the Power of GC×GC-TOFMS/FID – MOSH/MOAH

Unlock the Power of GC×GC-TOFMS/FID – MOSH/MOAH

Exciting advancements in analytical technology that are revolutionizing the way we identify and characterize these crucial components.

The most essential part of a GC×GC system is the modulator, so it is important to choose the right device for the application.
Join this webinar to hear from Dr. Laura McGregor, Product Marketing Manager at SepSolve Analytical, as she explores recent advances in GC×GC technology and how they are extending their capabilities from the niche to the mainstream.
Dr. McGregor will demonstrate the advantages of both flow and thermal modulation to help simplify the decision-making process. She will also show how robust and repeatable flow modulation allows GC×GC to be a productive member of high-throughput labs, while thermal modulation delivers the enhanced sensitivity and increased peak capacity for unparalleled characterisation of even the most challenging samples.
Furthermore, Dr. McGregor will share some examples of real-life applications that have benefited from the separating power of GC×GC using both flow and thermal modulation.
Key learning objectives
<ul>
<li>Understand the benefits of GC×GC and what it offers over and above standard GC
</li>
<li>Discover the advantages of both flow and thermal modulation
</li>
<li>Learn about the new INSIGHT-Thermal modulator for GC×GC
</li>
<li>Explore the latest GC×GC applications for both research and routine laboratories, including odor profiling, petrochemical fingerprinting and environmental monitoring
</li>
</ul>
Who should attend?
<ul>
<li>GC users who want to enhance their ability to analyse complex samples
</li>
<li>GC analysts who want to find out more about GC×GC
</li>
<li>GC×GC practitioners wanting to further their knowledge on recent advances in applications, hardware and software
</li>
</ul>
<blockquote>
Presenter: Dr. Laura McGregor (SepSolve Analytical)
</blockquote>
<blockquote>
Dr. Laura McGregor received an M.Chem in chemistry from the University of St Andrews, UK, followed by an M.Sc. in forensic science at the University of Strathclyde, UK. Her Ph.D. in environmental forensics, also at the University of Strathclyde, sparked her interest in GC×GC and she has been a strong advocate of the technique ever since. In her current role as Product Marketing Manager at SepSolve Analytical, she continues to apply GC×GC–TOF MS to challenging applications.
</blockquote>
<blockquote>
Presenter: Jemima Arnold (Editorial Team, SelectScience)
</blockquote>
<blockquote>
Jemima studied Cellular and Molecular Medicine at the University of Bristol, UK, and as a member of the Editorial team, she now plays an integral role in shaping the content on SelectScience.
</blockquote>

SelectScience: Adapting GCxGC for every challenge

Adapting GCxGC for every challenge

Recent advances in GC×GC technology and how they are extending their capabilities from the niche to the mainstream.

<h4>Key learnings:</h4>
<ul>
<li>Learn the basics of GC×GC and what it offers over and above standard GC.
</li>
<li>Hear about the latest advances in both flow and thermal modulation.
</li>
<li>Find out how automated software workflows can speed up data processing.
</li>
<li>Explore the latest GC×GC applications including the analysis of sustainable aviation fuels, pyrolysis oils, and much more.
</li>
</ul>

Gulf Bio Analytical Group: Improving GC×GC workflows for petrochemical analyses

Improving GC×GC workflows for petrochemical analyses

Explore the latest GC×GC applications including the analysis of sustainable aviation fuels, pyrolysis oils, and much more.

To coincide with the International Day of Women and Girls in Science, SepSolve Analytical is delighted to host the 3rd annual eseminar celebrating women in science. This year we will focus on GC×GC, with three exciting presentations about the use of the technique across a range of flavour and aroma applications.
<h5>A holistic approach to food quality assessment: The importance of combining comprehensive chemical and sensory analyses</h5>
<ul>
<li>Presenter: Natasha D. Spadafora (University of Ferrara, Italy)</li>
</ul>
<h5>Identification of novel non-terpenoid compounds in cannabis using comprehensive GC×GC-FID/MS/SCD</h5>
<ul>
<li>Presenter Twinkle Paryani (Abstrax Tech, USA)</li>
</ul>
<h5>Exploring the flavour profiles of plant-based milk</h5>
<ul>
<li>Presenter: Helena Leask (SepSolve Analytical, UK)</li>
</ul>

SepSolve Analytical: A Celebration of Women In Science 2024

A Celebration of Women In Science 2024

Three exciting presentations about the use of GC×GC across a range of flavour and aroma applications

In an era marked by intricate chemical compositions and emerging contaminants, conventional targeted analysis methods often prove inadequate for gaining a comprehensive understanding of environmental and biological matrices.
Enter non-targeted screening – an innovative approach enabling the simultaneous detection and identification of thousands of compounds, regardless of prior knowledge of their presence. Positioned at the forefront of this transformative methodology is ToFMS, distinguished by its unparalleled sensitivity, resolution, and mass accuracy.
Join us as we navigate the landscape of non-targeted screening using ToFMS, led by esteemed experts in the field. Uncover the transformative potential of this advanced analytical technique and explore its diverse applications across environmental monitoring, food safety, pharmaceutical analysis, and beyond.
Whether you&#39;re a seasoned scientist, industry professional, or eager learner, this webinar offers a unique opportunity to gain insights into the capabilities of non-targeted screening with ToFMS. Secure your spot now and embark on a journey of discovery in chemical analysis.
<h5>Webinar Program:</h5>
Professor Susan Richardson from the University of South Carolina will delve into her groundbreaking research on a newly discovered class of disinfection byproducts in drinking water. Using advanced techniques such as gas chromatography coupled with high-resolution mass spectrometry, Professor Richardson sheds light on the implications for water safety and public health. Discover the benefits of mass spectrometry for environmental analysis and gain insight into the future of drinking water quality assessment.
Additionally, Nick Jones, Global Applications Director of Separation Science at LECO, will provide a comprehensive overview of the applicability of LECO&#39;s GC×GC and ToFMS products across various industries requiring non-targeted screening. Explore the capabilities of these state-of-the-art technologies and their impact on advancing analytical methodologies.
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Presenter: Susan Richardson (Professor, University of South Carolina)
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Presenter: Nick Jones (Global Applications Director of Separation Science at LECO)
</blockquote>

LECO: TNon-Targeted Screening (NTS) Using Time-Of-Flight Mass Spectrometry (ToFMS)

Non-Targeted Screening (NTS) Using Time-Of-Flight Mass Spectrometry (ToFMS)

Welcome To Our Groundbreaking Webinar On Non-Targeted Screening (NTS) Using Time-Of-Flight Mass Spectrometry (ToFMS)

Non-Targeted Screening Using ToFMS

<h4>Event Overview</h4>
Understanding the intricate relationship between environmental factors, such as climate change and pest infestation, and the flavor, nutrition, and taste quality of crops is paramount for ensuring food security and agricultural sustainability.
However, analyzing such natural products poses several challenges because of their diverse matrices and wide-ranging volatile components.
In this webinar, Dr Luke Bell (University of Reading) will demonstrate how the enhanced separation of GC×GC-TOF MS, alongside advanced extraction and enrichment techniques, can unravel the complexities of plant and food volatiles. By integrating sensory evaluations with advanced analytical methodologies, this research aims to provide a deeper understanding of how climate change and pest pressures influence the volatile profiles of food produce.
By attending this webinar, you will:
<ul>
<li>Discover how integrating sensory evaluation with chemical characterization can enhance your understanding of aroma profiles.</li>
<li>Learn how chemometric data analysis can identify key features that distinguish between complex samples.</li>
<li>See real-world applications spanning food, flavor, and environmental sciences, including the volatile composition of honey, the effects of herbivory and pollution on poplar tree VOC emissions, and the effects of growing media on flavor compounds produced by kale.</li>
</ul>
Who should attend?
<ul>
<li>Food and flavor scientists seeking insights about potential applications</li>
<li>Plant and environmental scientists interested in field sampling techniques for volatiles</li>
<li>GC(–MS) users eager to explore the value of GC×GC for complex sample analysis</li>
</ul>
What you need to know:
Date: 10 July, 2024
Start times:
Broadcast #1: 10 July - 10 am BST (London) / 11 am CEST (Paris/Berlin) / 2:30 pm IST (New Delhi) / 5 pm SGT (Singapore) Broadcast #2: 10 July - 10 am PDT (Los Angeles) / 12 pm CDT (Chicago) / 1 pm EDT (New York)
Duration: Approximately 60 minutes
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Presenter: Luke Bell (Lecturer in Temperate Horticulture, University of Reading, UK)
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Dr Luke Bell is Lecturer in Temperate Horticulture at the University of Reading and holds degrees in Ecology &amp; Biology (BSc) and Plant &amp; Environmental Science (MSc), as well as a PhD in Food &amp; Nutritional Science from the University of Reading. He has previously worked in industry as a vegetable plant breeder and geneticist and now leads a research group at the University of Reading investigating crop-environment interactions, with a particular focus on how changes in the environment give rise to differences in nutrition, taste, and flavor quality of crops.
</blockquote>

Separation Science: Nature’s Influence: Understanding Environmental Impacts on Crop Flavor and Nutrition

Nature’s Influence: Understanding Environmental Impacts on Crop Flavor and Nutrition

Discover how GC×GC-TOF MS is used, alongside dvanced extraction techniques, to unravel the complexities of plant and food volatiles.

Environmental Impacts on Crop Flavor and Nutrition

<h3>Non-Targeted Screening with TOFMS: A Monthly Webinar Series</h3>
In an era marked by intricate chemical compositions and emerging contaminants, conventional targeted analysis methods often prove inadequate for gaining a comprehensive understanding of environmental and biological matrices. Enter non-targeted screening – an innovative approach enabling the simultaneous detection and identification of thousands of compounds, regardless of prior knowledge of their presence. Positioned at the forefront of this transformative methodology is Time of Flight Mass Spectrometry (TOFMS), distinguished by its unparalleled sensitivity, resolution, and mass accuracy.
Join us as we navigate the landscape of non-targeted screening (NTS) using TOFMS, led by esteemed experts within the field. Uncover the transformative potential of this advanced analytical technique and explore its diverse applications across environmental monitoring, food safety, pharmaceutical analysis, and beyond. Whether you’re a seasoned scientist, industry professional, or eager learner, this webinar offers a unique opportunity to gain insights into the capabilities of non-targeted screening with TOFMS.
Moreover, we’re excited to announce that what was once a standalone event has now evolved into a monthly webinar series. Nick Jones, the Global Applications Director of Separation Science at LECO, has invited key leaders of the NTS space from all industries to present and discuss their groundbreaking work. This series promises not only to delve deeper into the intricacies of non-targeted screening, but also to foster collaboration and knowledge exchange among experts and enthusiasts alike. Each session will last approximately 45 minutes, with a question and answer portion to follow.
<h3>This webinar:</h3>
NTS in Metabolomics:Insights from University of Liège
27 June, 2024 @ 1400 CEST
Nick Jones will regularly invite key leaders of the NTS space from all industries to present and discuss their groundbreaking work. This series promises not only to delve deeper into the intricacies of non-targeted screening but also to foster collaboration and knowledge exchange among experts and enthusiasts alike. Secure your spot now and embark on a journey of discovery in chemical analysis, with each instalments of our monthly webinar series delivering fresh perspectives and invaluable insights.
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Presenter: Prof Jean-François &quot;Jef &quot; Focant (University of Liège, Belgium)
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Professor Jef Focant, Head of the Department of Chemistry and Director of the Organic and Biological Analytical Chemistry Group at the University of Liège, Belgium will provide a comprehensive overview of testing complex matrices samples, elucidating the wealth of information that can be gleaned from their analysis across various application areas of metabolomics non-targeted screening using GCxGC-TOFMS.
</blockquote>
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Presenter: Dr. Pierre-Hugues &quot;PH&quot; Stefanuto (University of Liège, Belgium)
</blockquote>
<blockquote>
Dr. Pierre-Hugues Stefanuto, Lead Scientist and Lecturer at the University of Liège&#39;s Organic Biological Analytical Chemistry Group, will delve deeper into the microbiome application for metabolomics non-targeted screening. Dr. Stefanuto&#39;s presentation promises to offer intricate insights into the utilization of GCxGC-TOFMS for unraveling the complexities of microbiome samples, paving the way for innovative discoveries in metabolomics research.
</blockquote>
<h3>Upcoming Webinars</h3>
Secure your spot now and embark on a journey of discovery in chemical analysis, with each installment of our monthly webinar series delivering fresh perspectives and invaluable insights.
25 July | Flavor and Aroma
<ul>
<li>Dr. Geraint “Taff” Huw Morgan (The Open University, United Kingdom)</li>
</ul>
29 August | Forensics
<ul>
<li>Dr. Kate Perrault Uptmor (William &amp; Mary University, Williamsburg, VA, USA)</li>
</ul>

LECO: Non-Targeted Screening with TOFMS: A Monthly Webinar Series

NTS in Metabolomics: Insights from University of Liège

Nick Jones will regularly invite key leaders of the NTS space from all industries to present and discuss their groundbreaking work. This series promises not only to delve deeper into the intricacies of non-targeted screening but also to foster collaboration and knowledge exchange among experts and enthusiasts alike. Secure your spot now and embark on a journey of discovery in chemical analysis, with each instalments of our monthly webinar series delivering fresh perspectives and invaluable insights.
<blockquote>
Presenter: Dr. Geraint Huw Morgan (Open University, UK)
</blockquote>
<blockquote>
Dr. Geraint Huw Morgan, STEM Research Infrastructure Lead and Director of the Centre for Analytical Solutions at the Open University, UK, will present an in-depth exploration of non-targeted screening techniques for complex aroma profiles in this upcoming webinar. Drawing on his extensive experience in developing advanced methods for volatile organic compounds (VOCs), Dr. Morgan will highlight innovative approaches and methodologies using advanced technologies like GCxGC-MS, and TOF-MS.
</blockquote>
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Dr. Morgan&#39;s research in the world of aroma analysis spans across various sectors, from distilled spirits to fragrance industries all the way to measurement of bacteria in samples from outer space.
</blockquote>

GCMS webinars focusing on GCxGC - page 4

New Dimensions in Non-Targeted Screening of Complex Aroma Profiles