<div>In 2025, two outstanding young female researchers, Drs. Filipa Oliveira and Stella Gonsales, both originally from outside the Czech Republic, received prestigious JUNIOR STAR grants from the Czech Science Foundation (GAČR). JUNIOR STAR enables early career researchers to establish their own independent research groups and significantly advance their scientific careers. Their projects reflect cutting-edge research in materials science and sustainable chemistry, highlighting the international reach and welcoming research environment at UCT Prague.Dr. Stella Gonsales is also a&nbsp;laureate of the Dagmar Procházková Fund, which supports promising scientific projects in sustainable and advanced organic chemistry. Another recipient of this grant is Dr.&nbsp;Anna Valunchene, whose research complements UCT Prague’s&nbsp;sustainability goals. This dual funding underlines Stella’s&nbsp;remarkable achievements and the wide scope of innovative research at UCT Prague.Both Filipa and Stella are actively looking for motivated students and researchers to join their teams, offering a&nbsp;unique opportunity to work at the forefront of science in a&nbsp;vibrant and supportive environment.</div><div><h3>Interview with Filipa Oliveira: Pioneering tubular MXenes for supercapacitor energy storage</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_2_da6e538579.jpeg" alt="VŠCHT Prague: JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science: Filipa Oliveira" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_2_da6e538579.jpeg 235w," sizes="100vw" width="1500" height="999"><h5>Congratulations on receiving the JUNIOR STAR grant. What does this achievement mean for you and how will it influence your next steps?</h5>Thank you. It’s&nbsp;a huge achievement to receive this prestigious grant. It gives me the opportunity to establish my own research group here at UCT Prague. The JUNIOR STAR program supports talented young scientists in building their teams and accessing resources. This means I&nbsp;now have the support to focus fully on my research about tubular MXenes and their application in supercapacitors.<h5>Why are tubular MXenes so innovative for energy storage?</h5>MXenes are a family of 2D materials with a layered, accordion-like structure and known for their excellent electrical conductivity. Our innovation is to produce them with a tubular morphology, combining the high conductivity and redox activity in superior ion-transport tubular architectures. Their open, hollow structure increases surface area, ion diffusion and charge transport. This could translate to faster, more efficient supercapacitors, critical for sustainable energy technologies.<h5>How did your scientific interest lead you to this field?</h5>Global challenges around green energy made me focus on materials that can improve energy storage. MXenes stood out because changes in the composition and structure can significantly change their properties. I&nbsp;was curious about how tuning different metallic elements in a&nbsp;tubular morphology can impact how MXenes perform and how to optimize them for practical applications.<h5>What challenges have you encountered?</h5>One major challenge is their stability: MXenes oxidize quickly which deteriorates performance. Another challenge is understanding how synthesis conditions of both MXenes and their precursors (MAX phases) must be adapted to create and preserve tubular morphologies since their synthesis mechanisms differ from conventional MXenes. Additionally, effectively communicating the project in the funding proposal to show to reviewers why I&nbsp;should obtain this funding was also a&nbsp;challenge, but thanks to mentorship and collaboration, I&nbsp;overcame these hurdles.<h5>What motivates you most about working at UCT Prague?</h5>The support from colleagues and the excellent technical infrastructure make it a&nbsp;great place to work. Also, being a&nbsp;former member of Professor Sofer’s&nbsp;leading group in 2D&nbsp;materials is inspiring and led me to this achievement.<h5>How do&nbsp;you see your professional development going in the future?</h5>The grant will help me build my own team, acquire equipment, and develop collaborations. My long-term vision is to contribute significantly to sustainable energy solutions and scientific progress both locally and internationally.<h5>You are looking for new team members. What kind of students or scientists do&nbsp;you need?</h5>We are currently welcoming enthusiastic master's&nbsp;students, PhD candidates, and postdocs who are passionate about materials science and eager to explore new frontiers in MXenes and energy storage. If you love curiosity-driven research and want to be part of a&nbsp;growing international team, we encourage you to join us.<h3>Interview with Stella Gonsales: Catalysis as a&nbsp;key to polymer recycling</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_3_3d0ded6274.jpeg" alt="VŠCHT Prague: JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science: Stella Gonsales" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_VSCHT_Praha_V_prestizni_soutezi_GACR_uspely_dve_zahranicni_vedkyne_z_VSCHT_3_3d0ded6274.jpeg 233w," sizes="100vw" width="1499" height="1000"><h5>Congratulations on your JUNIOR STAR grant and also being awarded the Dagmar Procházková Fund. What does receiving both mean to you and how will they shape your work?</h5>Thank you. Both grants are hugely important. The JUNIOR STAR grant allows me to expand my group and resources for research into catalytic recycling of polymers, while the Dagmar Procházková Fund supports complementary projects such as synthesizing new biodegradable polymers. Together, they help tackle the plastic waste problem from multiple scientific angles.<h5>Could you explain your research in layperson’s&nbsp;terms?</h5>Most plastics have strong carbon-carbon bonds. We insert more cleavable double bonds into polymers that can be broken down by catalytic reactions called olefin metathesis, making recycling on a&nbsp;molecular level more feasible.<h5>What makes the JUNIOR STAR grant particularly important for your research and career development?</h5>The JUNIOR STAR grant is a&nbsp;prestigious and highly competitive funding opportunity aimed at excellent early-career scientists within eight years of completing a&nbsp;Ph.D. It provides up to 25&nbsp;million CZK over five years, allowing recipients to establish independent research groups and pursue innovative scientific topics. This grant is crucial for building a&nbsp;solid foundation, acquiring necessary equipment, and recruiting talented team members, enabling the pursuit of ambitious projects that can significantly contribute to both the Czech scientific community and global challenges.<h5>What collaborations support your research?</h5>The collaboration between UCT Prague and the Institute of Organic Chemistry and Biochemistry (IOCB) of the Czech Academy of Sciences primarily provides financial and technical support. The cooperation helps with funding, access to advanced equipment, and operational resources needed for running research projects.<h5>What advice would you give young scientists aiming to succeed?</h5>I&nbsp;encourage thinking outside the box and combining diverse knowledge you acquire during your career to address complex problems that are exciting and relevant to you.<h5>Your laboratory bears the name of Otto Wichterle and was ceremonially opened in the presence of Professor Kamil Wichterle. How does Wichterle’s&nbsp;legacy inspire you personally?</h5>Wichterle’<s>’</s>s&nbsp;innovative spirit motivates me to push creative boundaries and pursue novel solutions in sustainable chemistry.<h5>What are your visions for the future?</h5>I&nbsp;aim to build a&nbsp;research group that advances sustainable polymer recycling, contributing to environmental responsibility and the circular economy.<h5>You are recruiting people for your team. What skills do&nbsp;they need to have?</h5>We are looking for talented Ph.D. students and postdocs experienced in air-sensitive catalysis techniques. If you want to contribute to transformative research in sustainable chemistry and join a&nbsp;dynamic team, this is a&nbsp;great opportunity.</div>

JUNIOR STAR Grants at UCT Prague: Two talented women from abroad driving innovation in science

News from LabRulezGCMS Library - Week 06, 2026

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from deoxyribonucleic acid (DNA) into ribonucleic acid (RNA) can be initiated. The researchers focused on a specific class of molecules known as alarmones, which are found in cells across a wide range of organisms and whose levels often increase under conditions of cellular stress. The results were published in the prestigious scientific journal Nature Chemical Biology.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_bc2bfffa6c.jpg" alt="IOCB Prague/Tomáš Belloň: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: Dr. Hana Cahová, head of the Chemical Biology of Nucleic Acids research group." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_bc2bfffa6c.jpg 234w," sizes="100vw" width="2000" height="1335"><div>Molecules of ribonucleic acid can carry a variety of chemical modifications at one end, known as caps. In eukaryotic organisms, including human cells, the best-known cap plays an important role in RNA stability and in regulating its subsequent fate. In recent years, however, it has become clear that alternative, non-canonical RNA caps also exist, although their formation and the mechanisms by which they are attached to RNA remain only partially understood. These include alarmone caps, formed by dinucleoside polyphosphate molecules, that protect cellular RNA at moments when the cell is under threat.In their study, <a target="_blank" rel="noopener noreferrer" href="https://cahova.group.uochb.cz/en">Dr. Hana Cahová</a> and colleagues examined bacterial RNA polymerase and investigated how this enzyme can initiate transcription using dinucleoside polyphosphates (NpNs) instead of the standard RNA building blocks. For the first time, the scientists described, at the atomic level, how RNA bearing an alarmone cap can be generated directly at the initiation of gene transcription. They also observed that NpNs bind through a different type of base pairing than is typically observed.The work was significantly shaped by Valentina Serianni from Hana Cahová’s team, who demonstrated the ability of dinucleoside polyphosphates to initiate gene transcription, and by Jana Škerlová, who focused on the structural analysis of RNA polymerase. Using cryogenic electron microscopy data, she showed how dinucleoside polyphosphate molecules bind within the active site of RNA polymerase – that is, the core of the enzyme where genetic information is transcribed. Together, their findings help to elucidate the processes that accompany the transcription of genetic information from DNA to RNA.Hana Cahová adds: “We’re describing something that truly occurs in cells and that we’re now able to observe directly at the level of individual molecules. This allows us to answer fundamental questions about cellular processes, such as how cells adapt to stress. RNA plays a central role in this, as it carries the cascade of information underlying any cellular response – for example, to threatening conditions caused by nutrient deprivation or temperature shock.”<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_2_0fe88ff9e9.jpg" alt="IOCB Prague/Tomáš Belloň: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: Dr. Tomáš Kouba, head of the Cryogenic Electron Microscopy core facility." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_2_0fe88ff9e9.jpg 234w," sizes="100vw" width="2000" height="1335"><div>Cryogenic electron microscopy (cryo-EM) was central to the project. This part of the work was led by Dr. Tomáš Kouba, one of the authors of the study. “Cryogenic electron microscopy allows us to freeze biological molecules in a state very close to their natural form and then determine their three-dimensional structure. This makes it possible to look directly into the active centers of enzymes and observe their function down to the atomic level,” he explains.Last year, IOCB Prague opened a new <a target="_blank" rel="noopener noreferrer" href="https://cryoem.group.uochb.cz/en">cryo-EM center</a> that is unique within the Czech research environment. State-of-the-art cryogenic electron microscopes are housed in a specially designed building and enable the study of biological processes with exceptional structural precision.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_3_4d881e7a58.jpg" alt="IOCB Prague: Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription: This work shows how NpnNs initiate bacterial transcription. Cryo-EM reveals how nucleobases pair with the template: one in canonical and one in reverse Watson–Crick mode, providing a structural basis for their function as non-canonical RNA caps." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Vyzkum_z_UOCHB_odhaluje_dosud_nepoznany_zpusob_prepisu_geneticke_informace_3_4d881e7a58.jpg 245w," sizes="100vw" width="2000" height="1077"><blockquote><h4>The Original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41589-025-02134-5">Molecular insight into 5′ RNA capping with NpnNs by bacterial RNA polymerase</a></h4>Valentina M. Serianni, Jana Škerlová, Anna Knopp Dubánková, Anton Škríba, Hana Šváchová, Tereza Vučková, Anatolij Filimoněnko, Milan Fábry, Pavlína Řezáčová, Tomáš Kouba &amp; Hana Cahova&nbsp;Nat. Chem. Biol. 21 (2026)<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1038/s41589-025-02134-5">https://doi.org/10.1038/s41589-025-02134-5</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>RNA capped with dinucleoside polyphosphates has been discovered in bacteria and eukaryotes only recently. The likely mechanism of this specific capping involves direct incorporation of dinucleoside polyphosphates by RNA polymerase as noncanonical initiating nucleotides. However, how these compounds bind into the active site of RNA polymerase during transcription initiation is unknown. Here, we explored transcription initiation in vitro, using a series of DNA templates in combination with dinucleoside polyphosphates and model RNA polymerase from Thermus thermophilus. We observed that the transcription start site can vary on the basis of the compatibility of the specific template and dinucleoside polyphosphate. Cryo-electron microscopy structures of transcription initiation complexes with dinucleoside polyphosphates revealed that both nucleobase moieties can pair with the DNA template. The first encoded nucleotide pairs in a canonical Watson–Crick manner, whereas the second nucleobase pairs noncanonically in a reverse Watson–Crick manner. Our work provides a structural explanation of how dinucleoside polyphosphates initiate RNA transcription.</div></div>

Research from IOCB Prague reveals a previously unknown mechanism of genetic transcription

Article

Application

Scientists

Science and research

Video

The University of Chemistry and Technology, Prague is a natural centre of first-rate study and research in the area of chemistry in Czechia and is one of the country's largest educational and research institutions focused on technical chemistry, chemical and biochemical technologies, material and chemical engineering, food chemistry, and environmental studies.

UCT Prague

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Separation Science

Gulf Bio Analytical Group

Agilent Technologies

SepSolve Analytical

LECO

SelectScience

In today&#39;s competitive market, quality and protection of your brands are vital for staying ahead of your competitors. Discover how powerful technology can enhance your workflows, elevate brand quality and empower your Aroma, Flavour and Fragrance analysis.
In this informative webinar, we will explore how LECO technology is being used in the market to tackle common challenges faced by the Aroma, Flavor and Fragrance industry. Our experts will showcase innovative techniques such as:
<ul>
<li>GC×GC-TOFMS-Pegasus BT4D for allergens quantification</li>
<li>Hydrogen carrier gas for speed and cost saving</li>
<li>SYNC software for data sets</li>
</ul>
Learn how these advanced technologies and software can improve your workflow, enhance quality control, protect your supply chain, maintain brand quality and reputation, ensure safety, and shape consumer perception.
We will end the webinar with a live demonstration at our European Application &amp; Technology Center in Berlin, and a Q&amp;A session, so come prepared with your questions!

LECO: State of the Art Technology for Aroma, Flavour and Fragrance Analysis

State of the Art Technology for Aroma, Flavour and Fragrance Analysis

We will explore how LECO technology is being used in the market to tackle common challenges faced by the Aroma, Flavor and Fragrance industry.

Technology for Aroma, Flavour and Fragrance Analysis

Join Agilent and GERSTEL for our annual virtual seminar discussing how you can assure safety, authenticity, and quality of alcoholic beverages. Sharing the latest in technology developments and capabilities, new applications, and customer stories. Topics include distilled beverages, wine and beer. There is something for everyone in this seminar series and we hope to see you there.
Attend live and receive an Agilent GC wine glass!
<h3>Presentation 1: Non-targeted and Targeted Analysis of Spirits Aroma/Flavor Compounds using DHS-GC(-GC)-MS</h3>
Chromatographic analysis of distilled spirits has witnessed a sea change over a recent short period of years. Previous approaches which relied on solvent extraction procedures to enrich the secondary aroma/flavor compounds from the dominant ethanol-water base, can now be replaced by solventless, automated instrumental methods. Such solventless approaches comprise Stir Bar Sorptive Extraction, Static and Dynamic Headspace and Large Volume Injection. These methods rely on the ability of a PTV (Programmable Temperature Vaporization) injector to enrich analytes of interest before transfer to the GC column, while venting unwanted matrix.
Complex GC-MS data files obtained in this way, can also be further processed by powerful filters such as Spectral Deconvolution followed by RI based isolation and verification of identities of aroma/flavor compounds. The sequential progress of the GC-MS data file through these various filters and finally into a chemometric software for investigative discrimination of samples is achieved by simple mouse clicks. This is a very attractive outcome for practicing flavor Chemists and could be regarded as the final fulfillment of what previously could only be an outcome to aspire to.
These solventless techniques can be so efficient, and sometimes give such complex GC-MS data files, that often an additional chromatographic dimension may be required, especially for detection of ultra-trace compounds. This is supplied by chromatographic heart cutting where elution segments from one column are transferred to a second column of different polarity for increased resolution. The necessary instrumental configurations required for this purpose are also available in fully automated format.
Key Learning Objectives/What attendees will learn:
<ul>
<li>Appreciation of how analysis of distilled spirits has moved into a more modern approach using solventless extraction techniques featuring full automation from sample treatment to GC injection.</li>
<li>Aroma Office in conjunction with MS Spectral Deconvolution will be introduced as a powerful combination for filtering and listing of aroma compounds from complex GC-MS data files.</li>
<li>Two-dimensional Gas Chromatography (2D-GC-GC) will also feature as a valuable tool for isolation of key compounds from interfering matrix in extremely complex data files.</li>
</ul>
Who Should Attend: Chemists and Technicians involved in aroma research and analysis
<blockquote>
Presenter: Dr. Kevin Mac Namara (Consultant)
</blockquote>
<blockquote>
Dr Kevin Mac Namara graduated from the National University of Ireland with a speciality in synthetic organic chemistry. He later joined the Irish Government Alcohol Monopoly and subsequently moved to Irish Distillers Group in 1981 as Head of Technical Development where he established a high profile centre for distilled spirits research. When Irish Distillers merged into the global Pernod Ricard Group in 1990 he assumed a much enlarged role and represented Ireland in EU alcohol affairs for many years before retiring in 2012.
</blockquote>
<h3>Presentation 2: A Variety of Extraction Techniques Used to Determine Analytes of Interest in Distilled Spirits</h3>
Analysis of distilled spirits using GC-MS can be challenging due to the multitude of flavor and aroma compounds that exist in the predominantly ethanol-water mixture. The optimal extraction technique or techniques must be able to isolate and pre-concentrate the analytes before introduction into the GC-MS to produce meaningful data. GERSTEL offers numerous automated sample introduction and extraction techniques including Static Headspace (SHS), Solid Phase Microextraction (SPME), Thermal Desorption (TD), Dynamic Headspace (DHS), and Thin Film Solid-Phase Microextraction (TF-SPME) and Pyrolysis. GERSTEL offers additional features to each extraction technique including Multiple Headspace Sample Enrichment (MHSE) and TDx Multidesorption that can provide significantly more mass on column and lower detection limits. GERSTEL also offers unique detection capabilities with the olfactory detection port (ODP) allowing the analyst to smell compounds as they elute from the GC column. With simultaneous mass spectral detection, key odor-active compounds can be identified in complex products.
Common challenges encountered when analyzing distilled spirits include reproducibility of batches, identifying and quantifying off-odors produced during the fermentation process, and consumer satisfaction, especially in the context of competitors, to name a few. This presentation will show how GERSTEL addresses these complex challenges by having a complete “toolbox” of extraction, introduction and detection options that can be combined and optimized as needed.
Key Learning Objectives/What attendees will learn:
<ul>
<li>Theory and applicability of SHS, SPME, SBSE, TF-SPME, DHS, and pyrolysis.</li>
<li>How to decide on the most optimal extraction technique based on research challenges.</li>
</ul>
Who Should Attend: Analytical chemists in the food, flavor, fragrance, and beverage industries
<blockquote>
Presenter: Megan Harper (Applications Scientist l, GERSTEL, Inc.)
</blockquote>
<blockquote>
Megan Harper graduated from the University of Maryland Baltimore County in 2020 with a Bachelor of Science Degree in chemistry and received her Master of Science Degree in forensic science with an analytical chemistry track from Towson University in 2022. At GERSTEL, Inc., Harper applies her knowledge on sample extraction and introduction techniques to help solve complex problems for customers across the USA, including those involving distilled spirits.
</blockquote>

Pixabay/Bruno/Germany: 3rd Annual Alcoholic Beverages Virtual Symposium - Spirits

3rd Annual Alcoholic Beverages Virtual Symposium - Spirits

Non-targeted and Targeted Analysis of Spirits Aroma/Flavor Compounds using DHS-GC(-GC)-MS. Extraction Techniques Used to Determine Analytes of Interest

As the demand for plant-based food substitutes continues to rise, attention has turned to improving the flavour of these products, as they often lack the richness and complexity that consumers expect from traditional meat and dairy products.
In this webinar, Dr. Laura McGregor, Product Marketing Manager at SepSolve Analytical, will describe how to overcome common challenges associated with sampling and analyzing aroma volatiles using novel, automated extraction techniques combined with GCxGC-TOF MS and easy-to-use data analysis software. She will demonstrate this workflow for a range of food matrices, including protein powders, meat and dairy substitutes, and even plant-based ‘milk’ chocolate.
<h5>Key learning objectives</h5>
<ul>
<li>Explore new techniques for the extraction and analysis of aroma volatiles to gain an understanding of plant-based flavorings</li>
<li>Discover how GC×GC–TOF MS can provide more comprehensive aroma profiles and improved detection of off-odours</li>
<li>Learn how smart software can automatically align and ‘spot the difference’ between complex aroma profiles to aid reverse engineering</li>
<li>Explore real-world examples, including the comparison of protein powders and chocolate alternatives</li>
</ul>
<h5>Who should attend?</h5>
<ul>
<li>GC(-MS) users who want to enhance their ability to analyze complex samples</li>
<li>Food, fragrance and flavor scientists interested in how advanced analytical techniques can provide a competitive edge</li>
</ul>
<h5>Certificate of attendance</h5>
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
<blockquote>
Presenter: Dr. Laura McGregor (Product Marketing Manager, SepSolve Analytical)
</blockquote>
<blockquote>
Laura’s background is in analytical forensic science, and her Ph.D. (at the University of Strathclyde, UK) focused on the chemical fingerprinting of environmental contamination using GC×GC-TOF MS. Following roles in application support and product marketing for Markes International’s TOF MS and software portfolios, she joined SepSolve in October 2017, where she continues to apply GC×GC–TOF MS to challenging applications.
</blockquote>
<blockquote>
Presenter: Sarah Thomas (SelectScience)
</blockquote>
<blockquote>
Sarah studied biology at the University of Bath, UK, and has worked in the Pharmaceutical Sciences Department of St. Jude Children’s Research Hospital, Memphis. As a member of the Editorial team, Sarah plays an integral role in shaping the content on SelectScience.
</blockquote>

SepSolve Analytical: Great taste and plant-based: Can advanced analytical tools help tackle flavour challenges in plant-based foods?

Great taste and plant-based: Can advanced analytical tools help tackle flavour challenges in plant-based foods?

How to overcome challenges associated with sampling and analyzing aroma volatiles using novel, automated extraction techniques combined with GCxGC-TOF MS.

Tackle flavour challenges in plant-based foods

Join SepSolve Analytical as they demonstrate how the latest advances in GC×GC hardware and software are extending the capabilities of the technique from the niche to the mainstream.
Flow modulation of the gas stream overcomes the practical difficulties of applying GC×GC for routine analyses and has reduced cost of ownership. Easy-to-use chemometrics tools make life easier by preventing data processing becoming the bottleneck of analytical workflows.
In this presentation, we’ll cover some fascinating examples of real-life applications that have benefited from the separating power of GC×GC, in both research and routine laboratories. These include biomarker discovery, aroma profiling and environmental monitoring:
<ul>
<li>Total petroleum hydrocarbons (TPH) – Robust and routine monitoring of total petroleum hydrocarbons (TPH) in environmental matrices using GC×GC-FID.
</li>
<li>Chemical fingerprinting of pyrolysis oils – Detailed characterisation of pyrolysis oils from solid waste plastics using GC×GC–TOF MS to identify possible contaminants, and help to refine process design.
</li>
<li>Biomarker discovery – Thermal desorption coupled with GC×GC–TOF MS to capture comprehensive breath profiles and uncover potential biomarkers of disease.
</li>
<li>Aroma profiling – Comparison of whisky aroma profiles by SPME–GC×GC–TOF MS to distinguish between whiskies from different regions and evaluate the impact of maturation.
</li>
</ul>
By attending this presentation you will:
<ul>
<li>Learn the basics of GC×GC and what it offers over and above standard GC
</li>
<li>Debunk the myths of GC×GC being a ‘research-only’ tool
</li>
<li>See how cutting-edge software tools can simplify everyday use of GC×GC
</li>
<li>Familiarise yourself with the latest GC×GC applications
</li>
</ul>
Who should attend:
<ul>
<li>GC and GC-MS users who want to enhance their ability to analyse complex samples
</li>
<li>Separation scientists who want to find out more about GC×GC
</li>
<li>GC×GC practitioners wanting to further their knowledge on recent advances in applications, hardware and software
</li>
</ul>
<blockquote>
Presenter: Laura McGregor (Product Marketing Manager, SepSolve Analytical)
</blockquote>
<blockquote>
Laura McGregor received an M.Chem. in chemistry from the University of St Andrews, UK, followed by an M.Sc. in forensic science at the University of Strathclyde, UK. Her Ph.D. in environmental forensics, also at the University of Strathclyde, sparked her interest in GC×GC and she has been a strong advocate of the technique ever since. In her current role as Product Marketing Manager at SepSolve Analytical, she continues to apply GC×GC–TOF MS to challenging applications.
</blockquote>

Separation Science: Demystifying comprehensive two-dimensional gas chromatography (GC×GC)

Demystifying comprehensive two-dimensional gas chromatography (GC×GC)

Examples of real-life applications that have benefited from the separating power of GC×GC, in both research and routine laboratories.

Comprehensive two-dimensional gas chromatography (GC×GC)

In the ever-evolving landscape of today&#39;s competitive market, the significance of maintaining the quality and safeguarding the integrity of your brands cannot be overstated.
It is becoming even more imperative to outpace your competitors by leveraging powerful technology which can enhance your workflows, elevate brand quality and empower your Aroma, Flavour and Fragrance analysis.
In this webinar, we explore the capabilities of LECO technology and the impact it is having on overcoming the challenges faced in the Aroma, Flavor, and Fragrance industry.
<h4>1. Enhanced Workflows for Essential Oils: Increase Confidence in QC Screening &amp; Characterisation</h4>
<ul>
<li>Presented by Sebastiano Panto
</li>
<li>Hydrogen Carrier Gas
</li>
<li>BT 1D GC-TOFMS
</li>
<li>Maximise efficiency with Sync Software
</li>
</ul>
<h4>2. Investigate Perfumes in Greater Depth &amp; Faster: Utilise GCxGC to characterise perfume complexity and understand important differences for both performance and quality assurance</h4>
<ul>
<li>Presented by Lena Dubois
</li>
<li>Unveiling the power of BT4D and GCxGC-TOFMS
</li>
<li>Distinguishing real from counterfeit perfumes
</li>
<li>Seamlessly navigate complexity with Tile Software
</li>
<li>Allergen analysis to ensure safety
</li>
</ul>
<h4>3. Non-Target Characterization and Simultaneous Quantitation for Reformulation of Complex Fragrance Samples with GCxGC-MS/FID</h4>
<ul>
<li>Presented by Dr. Liz Humston-Fuller
</li>
<li>Mastering BT4D, RFF, Splitter/FID technologies
</li>
<li>Characterisation in detail
</li>
<li>Confident quantification through enhanced FOD accuracy
</li>
</ul>
<h4>4. Whisky Analysis: Unravel the complexities and differences of Whiskies</h4>
<ul>
<li>Presented by Taff Morgan (The Open University)
</li>
<li>BT 1D/BT4D
</li>
<li>Complex characterisation
</li>
<li>Comparison of different origins and process types
</li>
<li>Fast interpretation of large sample sets with Sync/Tile
</li>
</ul>
By immersing yourself in these advanced technologies and software solutions, you stand to revolutionize your workflow, elevate quality control measures, protect your supply chain, uphold brand reputation, ensure product safety, and shape consumer perception.
<blockquote>
Presenter: (Alan Griffiths, Director of Separation Science Global Sales, LECO USA)
</blockquote>
<blockquote>
Initially joining LECO UK as an installation and service engineer 15 years ago before taking on the challenges of sales across the UK and Ireland territory, Alan has a vast experience and understanding of LECO’s separation science portfolio. In the webinar, Alan will both introduce the speakers and chair the Q&amp;A.
</blockquote>
<blockquote>
Presenter: (Dr. Liz Humston-Fuller, Applications Chemist, LECO USA)
</blockquote>
<blockquote>
Liz earned her PhD in Analytical Chemistry with Prof Robert Synovec in the group that developed the tile-based Fischer ratio algorithms that have been further developed in collaboration with LECO to underpin ChromaTOF Tile. Her presentation will introduce “Advanced processing software with ChromaTOF Tile &amp; ChromaTOF Sync.”
</blockquote>
<blockquote>
Presenter: (Dr. Lena Dubois, Applications Chemist, LECO Europe)
</blockquote>
<blockquote>
Lena has ten years’ experience in the field of application chemistry and gained her PhD under the mentorship of Prof. Jef Focant at Liège University. Lena will be discussing “Workflows for the assessment of key aroma compounds” by utilising the latest in advanced GC and GCxGC -TOFMS and data processing technologies.
</blockquote>
<blockquote>
Presenter: (Dr. Geraint (Taff) Morgan, Department of Physical Sciences, The Open University)
</blockquote>
<blockquote>
Taff is an analytical chemist with vast experience, applying his knowledge from the bottom of the ocean to the surface of a comet. His talk entitled “Comprehensive Evaluation of Scotch Whisky Aroma Profile Using SPME-GCxGC-TOFMS” will demonstrate the effective use of high-quality instrumentation and software to real world whisky samples.
</blockquote>

Explore the capabilities of LECO technology and the impact it is having on overcoming the challenges faced in the Aroma, Flavor, and Fragrance industry.

Discover the cutting-edge workflow for the analysis of Mineral Oil Saturated Hydrocarbons (MOSH) and Mineral Oil Aromatic Hydrocarbons (MOAH) using GC×GC-TOFMS/FID.
Join our exclusive webinar where we will delve into the exciting advancements in analytical technology that are revolutionizing the way we identify and characterize these crucial components.
What To Expect:
<h4>GC×GC-TOFMS: Unraveling The Mysteries Of MOH</h4>
<ul>
<li>Learn how to set up a robust classification method using GC×GC-TOFMS and the MOH-mix, enabling precise and reliable analysis
</li>
<li>Witness the power of the classification method as we apply it to real samples, gaining valuable insights into various matrices
</li>
<li>Explore the market substances in mineral oils and understand how they aid in verifying and characterizing the contamination source
</li>
<li>Unravel the complexity of the MOAH fraction as we demonstrate the separation and identification of different ring systems, as discussed in the “Draft opinion update risk assessment of MOH in food for public consultation” by the European Food Safety Authority
</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Figure_1_Schematic_view_of_the_GC_GC_TOFMS_FID_instrument_setup_b6949cc782/LECO-Figure-1-Schematic-view-of-the-GCGC-TOFMS-FID-instrument-setup.jpg" alt="LECO: Obrázek 1: Schematic view of the GC×GC-TOFMS-FID instrument setup"/>
<h4>GC×GC-FID: Expanding Possibilities For Mineral Oil Analysis</h4>
<ul>
<li>Discover the seamless hardware setup for aligning GC×GC-TOFMS and GC×GC-FID signals, combining the strengths of both technologies
</li>
<li>Explore our state-of-the-art software tool for quantifying MOSH and MOAH fraction with GC×GC-FID, which can be implemented for accurate verification of SCoPAFF values
</li>
<li>Dive into the capabilities of our innovative software tool for quantifying different ring systems within the MOAH fraction, enhancing the depth of your analysis
</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Figure_2_GC_GC_contour_plot_of_LECO_s_MOH_mix_which_is_used_to_setup_the_classification_method_within_the_Chroma_TOF_software_44db161d98/LECO-Figure-2-GCGC-contour-plot-of-LECO's-MOH-mix-which-is-used-to-setup-the-classification-method-within-the-ChromaTOF(r)-software.jpg" alt="LECO: Obrázek 2: GC×GC contour plot of LECO’s MOH mix which is used to setup the classification method within the ChromaTOF® software"/>
Why Attend:
<ul>
<li>This webinar is a must-attend for scientists, researchers, and professionals in the field of analytical chemistry and food safety. Gain a deeper understanding of the latest techniques and technologies used in MOSH/MOAH analysis, equipping you with the knowledge to elevate your research and ensure compliance with industry standards.</li>
</ul>
<blockquote>
 Presenter: Sebastiano Panto (LECO Europe B.V., Head of Separation Science Applications Europe)
</blockquote>
<blockquote>
Presenter: Stefan Vinnenberg (LECO Instrumente GmbH, Account Manager DACH &amp; BeNeLux – Separation Science)
</blockquote>

LECO: Unlock the Power of GC×GC-TOFMS/FID – MOSH/MOAH

Unlock the Power of GC×GC-TOFMS/FID – MOSH/MOAH

Exciting advancements in analytical technology that are revolutionizing the way we identify and characterize these crucial components.

The most essential part of a GC×GC system is the modulator, so it is important to choose the right device for the application.
Join this webinar to hear from Dr. Laura McGregor, Product Marketing Manager at SepSolve Analytical, as she explores recent advances in GC×GC technology and how they are extending their capabilities from the niche to the mainstream.
Dr. McGregor will demonstrate the advantages of both flow and thermal modulation to help simplify the decision-making process. She will also show how robust and repeatable flow modulation allows GC×GC to be a productive member of high-throughput labs, while thermal modulation delivers the enhanced sensitivity and increased peak capacity for unparalleled characterisation of even the most challenging samples.
Furthermore, Dr. McGregor will share some examples of real-life applications that have benefited from the separating power of GC×GC using both flow and thermal modulation.
Key learning objectives
<ul>
<li>Understand the benefits of GC×GC and what it offers over and above standard GC
</li>
<li>Discover the advantages of both flow and thermal modulation
</li>
<li>Learn about the new INSIGHT-Thermal modulator for GC×GC
</li>
<li>Explore the latest GC×GC applications for both research and routine laboratories, including odor profiling, petrochemical fingerprinting and environmental monitoring
</li>
</ul>
Who should attend?
<ul>
<li>GC users who want to enhance their ability to analyse complex samples
</li>
<li>GC analysts who want to find out more about GC×GC
</li>
<li>GC×GC practitioners wanting to further their knowledge on recent advances in applications, hardware and software
</li>
</ul>
<blockquote>
Presenter: Dr. Laura McGregor (SepSolve Analytical)
</blockquote>
<blockquote>
Dr. Laura McGregor received an M.Chem in chemistry from the University of St Andrews, UK, followed by an M.Sc. in forensic science at the University of Strathclyde, UK. Her Ph.D. in environmental forensics, also at the University of Strathclyde, sparked her interest in GC×GC and she has been a strong advocate of the technique ever since. In her current role as Product Marketing Manager at SepSolve Analytical, she continues to apply GC×GC–TOF MS to challenging applications.
</blockquote>
<blockquote>
Presenter: Jemima Arnold (Editorial Team, SelectScience)
</blockquote>
<blockquote>
Jemima studied Cellular and Molecular Medicine at the University of Bristol, UK, and as a member of the Editorial team, she now plays an integral role in shaping the content on SelectScience.
</blockquote>

SelectScience: Adapting GCxGC for every challenge

Adapting GCxGC for every challenge

Recent advances in GC×GC technology and how they are extending their capabilities from the niche to the mainstream.

<h4>Key learnings:</h4>
<ul>
<li>Learn the basics of GC×GC and what it offers over and above standard GC.
</li>
<li>Hear about the latest advances in both flow and thermal modulation.
</li>
<li>Find out how automated software workflows can speed up data processing.
</li>
<li>Explore the latest GC×GC applications including the analysis of sustainable aviation fuels, pyrolysis oils, and much more.
</li>
</ul>

Gulf Bio Analytical Group: Improving GC×GC workflows for petrochemical analyses

Improving GC×GC workflows for petrochemical analyses

Explore the latest GC×GC applications including the analysis of sustainable aviation fuels, pyrolysis oils, and much more.

To coincide with the International Day of Women and Girls in Science, SepSolve Analytical is delighted to host the 3rd annual eseminar celebrating women in science. This year we will focus on GC×GC, with three exciting presentations about the use of the technique across a range of flavour and aroma applications.
<h5>A holistic approach to food quality assessment: The importance of combining comprehensive chemical and sensory analyses</h5>
<ul>
<li>Presenter: Natasha D. Spadafora (University of Ferrara, Italy)</li>
</ul>
<h5>Identification of novel non-terpenoid compounds in cannabis using comprehensive GC×GC-FID/MS/SCD</h5>
<ul>
<li>Presenter Twinkle Paryani (Abstrax Tech, USA)</li>
</ul>
<h5>Exploring the flavour profiles of plant-based milk</h5>
<ul>
<li>Presenter: Helena Leask (SepSolve Analytical, UK)</li>
</ul>

SepSolve Analytical: A Celebration of Women In Science 2024

A Celebration of Women In Science 2024

Three exciting presentations about the use of GC×GC across a range of flavour and aroma applications

In an era marked by intricate chemical compositions and emerging contaminants, conventional targeted analysis methods often prove inadequate for gaining a comprehensive understanding of environmental and biological matrices.
Enter non-targeted screening – an innovative approach enabling the simultaneous detection and identification of thousands of compounds, regardless of prior knowledge of their presence. Positioned at the forefront of this transformative methodology is ToFMS, distinguished by its unparalleled sensitivity, resolution, and mass accuracy.
Join us as we navigate the landscape of non-targeted screening using ToFMS, led by esteemed experts in the field. Uncover the transformative potential of this advanced analytical technique and explore its diverse applications across environmental monitoring, food safety, pharmaceutical analysis, and beyond.
Whether you&#39;re a seasoned scientist, industry professional, or eager learner, this webinar offers a unique opportunity to gain insights into the capabilities of non-targeted screening with ToFMS. Secure your spot now and embark on a journey of discovery in chemical analysis.
<h5>Webinar Program:</h5>
Professor Susan Richardson from the University of South Carolina will delve into her groundbreaking research on a newly discovered class of disinfection byproducts in drinking water. Using advanced techniques such as gas chromatography coupled with high-resolution mass spectrometry, Professor Richardson sheds light on the implications for water safety and public health. Discover the benefits of mass spectrometry for environmental analysis and gain insight into the future of drinking water quality assessment.
Additionally, Nick Jones, Global Applications Director of Separation Science at LECO, will provide a comprehensive overview of the applicability of LECO&#39;s GC×GC and ToFMS products across various industries requiring non-targeted screening. Explore the capabilities of these state-of-the-art technologies and their impact on advancing analytical methodologies.
<blockquote>
Presenter: Susan Richardson (Professor, University of South Carolina)
</blockquote>
<blockquote>
Presenter: Nick Jones (Global Applications Director of Separation Science at LECO)
</blockquote>

LECO: TNon-Targeted Screening (NTS) Using Time-Of-Flight Mass Spectrometry (ToFMS)

Non-Targeted Screening (NTS) Using Time-Of-Flight Mass Spectrometry (ToFMS)

Welcome To Our Groundbreaking Webinar On Non-Targeted Screening (NTS) Using Time-Of-Flight Mass Spectrometry (ToFMS)

GCMS webinars focusing on GCxGC - page 4

Non-Targeted Screening (NTS) Using Time-Of-Flight Mass Spectrometry (ToFMS)

A Celebration of Women In Science 2024

Improving GC×GC workflows for petrochemical analyses

Adapting GCxGC for every challenge

Unlock the Power of GC×GC-TOFMS/FID – MOSH/MOAH

State of the Art Technology for Aroma, Flavour and Fragrance Analysis

Demystifying comprehensive two-dimensional gas chromatography (GC×GC)

State of the Art Technology for Aroma, Flavour and Fragrance Analysis

Great taste and plant-based: Can advanced analytical tools help tackle flavour challenges in plant-based foods?

3rd Annual Alcoholic Beverages Virtual Symposium - Spirits

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