<div><div>Moumita Das and Petr Bouř from IOCB Prague have demonstrated in a recent paper in the Journal of the American Chemical Society (JACS) that far-from-resonance magnetic Raman optical activity (MROA) is measurable for a wide variety of molecules and that its sensitivity does not depend on intrinsic molecular chirality. This discovery makes MROA a distinctive analytical method with potential applications in probing the conformational behavior of both chiral and achiral molecules in solution and other liquid systems.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/IOCB_Prague_Structural_sensitivity_without_chirality_Observation_of_magnetic_Raman_optical_activity_outside_resonance_5794fae70a.jpeg" alt="IOCB Prague: Structural sensitivity without chirality: Observation of magnetic Raman optical activity outside resonance" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_IOCB_Prague_Structural_sensitivity_without_chirality_Observation_of_magnetic_Raman_optical_activity_outside_resonance_5794fae70a.jpeg 245w," sizes="100vw" width="992" height="537"></div></div><div>Magnetic Raman optical activity (MROA) is traditionally associated with systems fulfilling resonance conditions, i.e., those absorbing the excitation radiation. Its presence in far-from-resonance (FFR) regimes, where absorption is negligible, has not been previously reported.In a recent study, Moumita Das and <a target="_blank" rel="noopener noreferrer" href="https://bour.group.uochb.cz/en">Petr Bouř</a> from IOCB Prague identified MROA signals under FFR conditions in a range of common organic molecules. This observation challenges the established understanding of the phenomenon and suggests that MROA is more general than previously assumed.The authors developed a theoretical description of the effect and implemented a computational protocol for simulating MROA intensities. The predicted spectral features show reasonable agreement with experimental data and reproduce observed trends.The results further indicate that MROA spectra are sensitive not only to molecular identity but also to conformational changes. Researchers also detected this structural sensitivity in solution even when molecules lacked intrinsic chirality.These findings position MROA as a potentially valuable analytical tool for conformational studies of both chiral and achiral molecules in liquids, with implications for spectroscopy and structural chemistry.<blockquote><h4>The Original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/jacs.5c22470">Structural Sensitivity without Chirality: Observation of Magnetic Raman Optical Activity outside Resonance</a></h4>Moumita Das, and Petr BouřJ. Am. Chem. Soc. 2026, 148, 10, 11058–11067<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/jacs.5c22470">https://doi.org/10.1021/jacs.5c22470</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>Magnetic Raman optical activity (MROA) has been considered to be confined to a few systems fulfilling the resonance conditions. In a far-from-resonance (FFR) case when the systems do not absorb the excitation radiation, it has not been reported. However, we find it present in many common organic molecules. The underlying theory was elaborated, and a procedure for quantum chemical simulations of MROA intensities was implemented. The spectral features predicted at the density functional theory (DFT) level reasonably agree with the observations, describe the trends in the experimental data, and allow one to understand the phenomenon more deeply. It appears that not only do molecules have specific MROA patterns but the intensities are also very much dependent on the conformation. The sensitivity to the structure in solutions without the need for intrinsic molecular chirality makes MROA a unique tool for analytical chemistry and potentially usable for conformational studies of both chiral and achiral molecules in solutions and other liquids.</div>

Structural sensitivity without chirality: Observation of magnetic Raman optical activity outside resonance

In today’s academic research environment, speed and precision are everything. Whether you're analyzing trace organic compounds, processing environmental extracts, or running a high-throughput metabolomics project, one bottleneck continues to slow down even the most well-equipped labs: solvent evaporation.If your lab still relies on aging hot plates or hand-drying methods, you’re not alone. But the consequences are real: inconsistent recovery, lost analytes, and valuable hours wasted each week.<h3>The Hidden Cost of Manual Evaporation</h3>Many academic labs were built on traditional sample prep methods. But as research needs evolve and sample volumes increase, these outdated tools can no longer keep up.Manual evaporation doesn’t just slow workflows—it undermines reproducibility.Hot plates can over-dry samples or introduce uneven heating that degrades sensitive compounds. Open evaporation risks contamination. And when multiple students share equipment, timing differences from sample to sample introduce variability that shows up later as noisy chromatography or inconsistent quantitation.Students and faculty alike often report frustration with drying steps taking far too long, especially when preparing dozens of samples for <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-lc-ms/ms-analysis?hsLang=en">LC-MS</a> or <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-gc-ms/ms-analysis?hsLang=en">GC-MS workflows</a>. In some cases, samples left unattended can be partially lost or require re-preparation entirely.For grant-funded research, that wasted time and material adds up quickly.<h3>A Better Way: Controlled Nitrogen Blowdown</h3>Nitrogen blowdown evaporation replaces guesswork with control. A steady stream of inert nitrogen combined with gentle, regulated heat speeds evaporation while protecting sensitive analytes.<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=362&amp;manufacturerItems=540">Systems from Organomation </a>are designed specifically for sample preparation—not as improvised solutions or general lab accessories, but as purpose-built tools for consistent concentration.The result is straightforward:<ul style="list-style-type:disc;"><li>Faster dry-downs</li><li>Better recoveries</li><li>Improved reproducibility</li><li>Less hands-on time</li></ul>So researchers can focus on generating data instead of babysitting samples.<h3>Why Academic Labs Choose the N-EVAP</h3>Research labs rarely process identical samples all day.One student may be concentrating a small organic extract, another working with aqueous environmental samples, and a third reducing a larger crude matrix—all at the same time. That variability is exactly where many batch systems fall short.The<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=362&amp;manufacturerItems=540&amp;search=n-evap"> N-EVAP</a> transforms sample preparation uncertainty into control through radical flexibility.Unlike systems that force you to work around equipment constraints, the N-EVAP’s individual per-sample valves let you adjust gas flow, temperature exposure, and needle positioning for each sample—simultaneously.This isn’t theoretical flexibility. It means you can:<ul><li>Concentrate a 10 mL aqueous sample</li><li>Reduce a 5 mL organic extract</li><li>Evaporate a 50 mL environmental sample</li></ul>—all in the same run, without compromise.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/manual-to-automated-solvent-drying-is-it-worth-the-switch">Learn how the University of Cincinnati achieved 20x faster sample prep with the N-EVAP evaporator.</a></blockquote><ul><li>For academic programs handling variable matrices, this eliminates the false choice between batch efficiency and analytical precision. Each sample gets exactly the conditions it needs, preserving analyte integrity while maintaining throughput. &nbsp;</li><li>Available in configurations from <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2352">6</a> to <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1911">45 </a>positions—with optional digital controls on larger models—the system scales easily from small teaching labs to large research groups without forcing workflow changes. &nbsp;</li><li>It’s built for scientists who want control over their experiments, not workarounds. &nbsp;</li><li>Our evaporators are the <a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/why-organomation-is-the-most-cited-blowdown-evaporator-brand-in-u.s.-epa-methods">most cited nitrogen blowdown sample concentrators</a> in standardized EPA methods, making Organomation the trusted, fail proof choice.</li></ul><h3>Built for Chromatography Workflows</h3>Since 1959, Organomation has focused exclusively on sample preparation. That specialization shows in the details that matter most to chromatography labs: uniform heating, consistent gas distribution, compatibility with common vial formats, and rugged construction that stands up to daily use in shared academic spaces.Whether you're preparing samples for LC-MS, GC-MS, or other analytical methods, nitrogen blowdown helps ensure:<ul><li>Faster turnaround between experiments</li><li>Consistent recoveries</li><li>Fewer re-runs</li><li>Less student labor tied up in drying steps</li></ul>Which ultimately means more time spent on analysis, interpretation, and publication.<h3>Prove the Time Savings for Yourself</h3>Upgrading your evaporation workflow can clearly improve efficiency—but how much time would your lab actually save? ➔ Rather than guessing, you can calculate it.Organomation’s free <a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/evaporation-time-calculator-excel-download">Evaporation Time Savings Calculator</a> lets you enter your real lab conditions—sample counts, volumes, current dry-down times, and run frequency—to quantify exactly how much time nitrogen blowdown could save each week, month, or semester.For many academic labs, the results are eye-opening:<ul><li>Hours of student and staff time reclaimed</li><li>Faster LC-MS/GC-MS queues</li><li>Reduced bottlenecks before analysis</li><li>Hard numbers that help justify equipment purchases in grants and budgets</li></ul>In just a few minutes, you’ll have concrete data showing whether flexible evaporation makes financial and workflow sense for your lab.<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/evaporation-time-calculator-excel-download">Download the Evaporation Time Savings Calculator and see what your lab could save.</a></blockquote>

Is Your University Lab Losing Time and Data in Sample Prep? Here’s How to Fix It

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 20th April 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies and Shimadzu, brochure by BaySpec and presentation by MDCW / William &amp; Mary!<h3>1. Agilent Technologies: Analysis of Aromatic Amines in Textile Samples</h3>Using hydrogen carrier gas and an Agilent 8890 gas chromatography system coupled with an Agilent 5977C GC/MSD with an Agilent HydroInert source<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_amines_textile_gcms_5994_8997en_agilent_1a9ca88e41.pdf">Full PDF for download</a></li></ul>Azo dyes, characterized by the azo group (–N=N–), represent the largest class of synthetic organic colorants, accounting for approximately 70% of the global dye market with over 3,000 variants in use.1 Their widespread application in textiles, leather, plastics, cosmetics, food, and pharmaceuticals is attributed to their low cost, colorfastness, and structural versatility. Global textile dye production exceeded 1 million tons in 2020.1 Despite their industrial significance, azo dyes pose serious environmental and health concerns.1,2 Up to 15% of these dyes are discharged into wastewater or solid waste streams, and as much as 40% may be lost during textile processing. Resistant to degradation, they persist in ecosystems and can release harmful aromatic amines under certain conditions.1 Numerous GC/MS-based analytical methods are available for the estimation of amine compounds. These methods use helium as the carrier gas. For a sustainable analytical solution, there is a need for an alternative carrier gas to overcome the challenges occurring due to helium scarcity.&nbsp;The method adopted for this application note demonstrates the use of hydrogen as a carrier gas in the Agilent 8890 gas chromatography system coupled with the Agilent 5977C GC/MSD using a HydroInert source for the quantification of aromatic amines residues in textile&nbsp;samples.&nbsp;<h4>Experimental</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890">Agilent 8890 Gas Chromatography System</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=5977C">Agilent 5977C GC/MSD</a></li></ul><h4>Conclusion&nbsp;</h4>This application note presents key strategies for the analysis of amines using GC/MS with hydrogen as the carrier gas, while maintaining sensitivity to meet the maximum residue limits (MRLs) as mentioned in part 1 of ISO:14362. The method includes an Agilent J&amp;W DB-35ms column (20 m × 0.18 mm, 0.18 µm) and a hydrogen‑compatible electron ionization source, the Agilent HydroInert source. The optimized setup with hydrogen showed good chromatographic resolution. The HydroInert source was shown to provide good sensitivity. The method presented here allowed for the quantitation of 24&nbsp;target amines analytes at concentrations ranging from 0.25 to 20 µg/mL in an aqueous standard. Good repeatability was found with %RSD values below 5 for 22 of the 24&nbsp;compounds. Real world textile samples were also analyzed using the same method and three target compounds—aniline, o-toluidine, and benzidine—were observed as present in those samples.<h3>2. BaySpec: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2221">Ion-K9</a> The World’s First Portable, Non-Contact Trace Vapor Detector</h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/AFT_u_MS_flyer_final_e882bcb462.pdf">Full PDF for download</a></li></ul>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2221">Ion-K9</a> represents a breakthrough in trace detection technology as the world’s first portable, non-contact vapor detector. Designed for rapid and reliable field deployment, this system enables real-time identification of trace-level threats without the need for direct sample contact. By utilizing advanced vapor sampling and mass spectrometry, it provides a safe and efficient solution for detecting hazardous substances in security, forensic, and environmental applications .At the core of the Ion-K9 is a miniature linear ion trap mass analyzer combined with a non-radioactive ionization source, allowing detection of a wide range of explosives and narcotics. The system achieves ultra-high sensitivity down to parts-per-trillion levels (pptv), ensuring reliable identification of compounds such as TNT, RDX, fentanyl, and methamphetamine. Its ability to operate in both positive and negative ion modes further enhances detection flexibility across diverse chemical classes .The instrument is engineered for operational reliability in real-world environments, offering a low false alarm rate below 0.001% while maintaining detection rates above 99.999%. An integrated Intel® Core™ i7 system with a touchscreen interface provides intuitive operation and immediate visual feedback, enabling users to quickly assess whether a threat is present and access detailed analytical data when needed .With its compact, portable design and capability for battery operation, the Ion-K9 is well suited for deployment in airports, border control, law enforcement, and emergency response scenarios. By combining high sensitivity, rapid analysis, and non-contact sampling, it delivers a powerful tool for modern security and analytical workflows, ensuring both efficiency and operator safety in demanding environments.<h3>3. MDCW / William &amp; Mary: Developing a Combined Approach to Green Gunshot Residue Analysis in the Forensic Laboratory</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_24_Saunders_f2c5bcdb20.pdf">Full PDF for download</a></li></ul><section><div><div><div><div><div><div>The growing adoption of environmentally friendly (“green”) ammunition presents new analytical challenges for forensic laboratories, particularly in the detection of gunshot residue (GSR). Traditional approaches rely heavily on identifying inorganic particles containing heavy metals such as lead, barium, and antimony. However, green ammunition eliminates these markers, producing residues composed of more ubiquitous materials that are significantly harder to detect and interpret. This shift necessitates the development of new analytical strategies capable of identifying both inorganic and organic components of GSR.To address this challenge, a combined analytical approach integrating scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS) and comprehensive two-dimensional gas chromatography (GC×GC) was developed. SEM-EDS enables detailed morphological and elemental characterization of particles, identifying features such as size, shape, and elemental composition. In parallel, GC×GC provides enhanced separation and detection of organic gunshot residue (OGSR), offering significantly improved resolution and peak capacity compared to conventional one-dimensional GC methods.Method development focused on optimizing GC×GC parameters, including inlet temperature, modulation period, and chromatographic conditions, to improve analyte detectability. As illustrated by chromatographic data, optimized conditions led to better separation and increased visibility of key compounds compared to standard methods. The approach was validated using multiple standards, including phthalates, nitroaromatic compounds, nitroglycerin, and gun surveillance mixtures, demonstrating reliable identification of relevant analytes in complex matrices.Overall, this integrated workflow represents a promising strategy for modern GSR analysis, particularly for samples derived from green ammunition. By combining inorganic particle characterization with advanced organic residue analysis, the method enhances analytical confidence and expands the capability of forensic laboratories. Future work will focus on further method refinement, including sorbent-based extraction techniques and the incorporation of retention indices, to strengthen robustness and support admissibility under forensic standards.</div></div></div></div></div></div></section><h3>4. Shimadzu: Simple Aroma Component Analysis Using <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=gc-2060">Nexis GC-2060</a> with a Multi-Mode Inlet (MMI) Detectors</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_01165_en_9af6a30e20.pdf">Full PDF for download</a></li></ul><h5>User Benefits</h5><ul><li>By installing an MMI in a Nexis GC-2060 system, a wide variety of injection methods can be used .</li><li>By using a MonoTrap silica monolith sorbent to collect aroma components, highly sensitive analysis can be achieved without cumbersome extraction procedures.</li><li>With the MMI thermal desorption/extraction mode, aroma components can be analyzed without dedicated sample-preparation equipment.</li></ul>Given that aroma is an important attribute of foods, gas chromatography (GC) and gas chromatography–mass spectrometry (GC-MS) are often used for qualitative and quantitative analysis of aroma components. Aroma components are typically collected from foods using headspace sampling, solid-phase microextraction (SPME), or liquid extraction methods, but for this article, a MonoTrap silica monolith sorbent was used to collect aroma components from alcoholic beverages. With the MonoTrap, aroma components can be collected and concentrated without cumbersome extraction procedures, enabling highly sensitive analysis.&nbsp;In this case, aroma components were analyzed using a Nexis GC-2060 gas chromatograph system equipped with a MultiMode Inlet (MMI). The MMI is a newly developed inlet that supports a wide range of injection methods. This article describes using the thermal desorption/extraction mode, one of the methods available with the MMI, to desorb the aroma components collected on the MonoTrap sorbent and inject them into the GC unit. That enabled highly sensitive aroma analysis while reducing analysis costs, without using dedicated sample-preparation equipment.<h4>Overview of the Multi-Mode Inlet (MMI)</h4>The Nexis GC-2060 can be equipped with a Multi-Mode Inlet (MMI) (Fig. 1 (right)), a new type of inlet . The MMI is a newly developed inlet that allows many injection methods to be used with a single inlet—not only the commonly used split/splitless injection methods, but also programmed temperature vaporizing (PTV) injection, direct injection, large volume injection, and thermal desorption/extraction methods . It supports a wide range of applications across many fields, including analyzing pesticide residues in foods using largevolume injection and aroma analysis using thermal desorption. Because the MMI enables rapid temperature ramping at rates up to 1200 °C/min, it can suppress peak broadening. In addition, by selecting optional cooling with compressed air or liquid nitrogen, analysis cycle times can be shortened with fast cooling. The GC-2060 also comes standard with the “Easy sTop” function, which allows inlet maintenance to be performed immediately with simple steps, enabling smooth maintenance operations, such as insert replacement, even after cooling.<h4>Conclusion</h4>By analyzing aroma components using the Nexis GC-2060 in combination with a Multi-Mode Inlet (MMI) and a MonoTrap silica monolith sorbent, aroma characteristics of respective alcoholic beverages could be analyzed and evaluated easily without dedicated sample-preparation equipment and without performing cumbersome extraction procedures. Acknowledgements We would like to express our sincere gratitude to President Shiro Yamada and Mr. Dai Takai of Far Yeast Brewing Co., Ltd., and to President Narihiro Suzuki and Mr. Takuma Yamamiya of ISEKADO (Isekadoya Brewery) for their cooperation in conducting these measurements.

News from LabRulezGCMS Library - Week 17, 2026

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Presentation

Science and research

Laboratories

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

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Technology Networks

Bruker

Thermo Fisher Scientific

C&EN

<div>As gas chromatography instruments demand ever higher hydrogen purity, many labs are also under pressure to reduce environmental impact and operating costs.This webinar explores how recent advances in hydrogen gas generation are addressing both challenges at once. Dr. Ed Connor and Ian Cameron will discuss the current limitations of traditional gas supply methods and how modern on-site generation is reshaping laboratory workflows.As an attendee, you will gain insight into how today’s technologies can support consistent performance, greater reliability and more sustainable lab operations without compromising analytical quality.<h4>Attend this webinar to:</h4><ul><li>Learn how a gas generator can improve your lab’s uptime</li><li>Understand the operational efficiencies and cost savings you can get from an in-house gas generator</li><li>Gain insights into the sustainable, energy efficient benefits of on-site gas generation&nbsp;</li></ul><blockquote>Presenter: Ian Cameron (Hydrogen Design Team Lead at PEAK Scientific)As the Design Team Lead at PEAK Scientific Instruments, Ian guides a multidisciplinary team of engineers and designers in creating advanced scientific equipment for laboratory and analytical applications. With a background in mechanical engineering and physics and 15 years in the manufacturing and design industry, Ian brings a strong understanding of the scientific principles and engineering practices that underpin high performance instrumentation.Presenter: Ed Connor, PhD (Product Manager at PEAK Scientific)Dr. Ed Connor joined PEAK in 2013 as a gas chromatography (GC) product specialist before moving on to product management. He’s been working on many collaborative projects with PEAK customers and major instrument manufacturers worldwide. The main focus of these collaborations has been looking at conversion from helium to hydrogen carrier gas for GC applications. Ed completed his doctor of science degree at ETH Zurich in 2007 using GC-Mass Spectrometry (GC-MS) to look at herbivore induced plant volatiles and their interaction with beneficial insects. He then joined the University of Zurich where his work focused primarily on floral volatiles analysis using a variety of volatile collection methods, GC-MS and GC-Flame Ionization Detection.</blockquote></div>

Technology Networks: Advances in Hydrogen Gas Generation for Sustainable Laboratories

Advances in Hydrogen Gas Generation for Sustainable Laboratories

Webinar on hydrogen gas generation for GC, covering uptime improvement, cost savings, sustainability, and helium-to-hydrogen conversion strategies.

Hydrogen Gas Generation for Sustainable Laboratories

<div>Learn about how Fourier-Transform Infrared (IR) and Electron Paramagnetic Resonance (EPR) spectroscopies enable in-depth understanding of polymer reactions. This webinar will review two main topics:<ul><li>The curing process of polymers and how FT-IR allows for real time monitoring of kinetics and degree of cure, with calibration protocols to measure conversion percentages.</li><li>The use of EPR spectroscopy to study radical mechanisms involved in polymerization, degradation, and stability of polymer materials.</li></ul><h4>Webinar Overview</h4>Polymers are an integral part of everyday life, from household goods to various fields of research and industrial applications. The ability to study the formation, degradation and stability of polymers is an important endeavor in the development of materials with better performance and longevity. Join us for this informative webinar on understanding the mechanisms and kinetics of various polymer processes via Fourier-Transform Infrared (FT-IR) and EPR Spectroscopy.The polymer curing process, from reaction kinetics to quantification of the process, is important to understand for new materials. FT-IR is highly suited for tracking the curing process due to its sensitivity to changes in functional groups We will showcase the ability of FT-IR in monitoring reaction kinetics and quantifying the degree of cure. Attendees will also gain technical insights into optimized workflows for R&amp;D and QA environments. &nbsp; Polymerization or degradation of polymer materials can often involve the formation of free radicals. The best suited method for unambiguous detection of free radicals in polymer processes is EPR Spectroscopy, which is a high-sensitivity, versatile and non-destructive technique. We will showcase the ease-of-use the Magnettech ESR5000 benchtop spectrometer and how users can incorporate workflows to identify radicals/impurities, track kinetics, and stress test polymer materials. &nbsp;&nbsp;<h4>What to Expect</h4>In this webinar, we will show how FT-IR and EPR methods provide valuable information during polymer formation and degradation processes. Learn how FT-IR can track reaction kinetics in real time and provide calibration procedures for the curing process. Dive into EPR as a robust, non-destructive technique for studying radical driven mechanisms in polymer materials under diverse conditions.<h4>Key Learning Points</h4>This webinar demonstrates how FT-IR and EPR are suitable for studying polymer reactions and kinetics under various conditions<ul><li>FT-IR workflows for kinetics of curing and quantifying degree of cure</li><li>Case studies using UV treated acrylates and calibration procedures for curing percentages</li><li>EPR for tracking free radical driven processes in polymer reactions, degradation and testing of polymers exposed to various stimuli</li></ul><h4>Who Should Attend?</h4><ul><li>Polymer chemists and researchers developing new materials</li><li>Industry professionals working with polymer materials looking to add screening tools to their workflows</li><li>Polymer scientists wanting to understand the radical mechanisms that drive processes such as polymerization or degradation</li></ul><blockquote>Presenter: Alvaro Montoya (Ph.D. in chemistry from the University of Florida, EPR Application Scientist, Bruker BioSpin)Alvaro Montoya began his EPR career as a Ph.D. student at the University of Florida after obtaining his B.S. in Chemistry from Susquehanna University. Early in his graduate career, he made use of CW and High Field EPR in studying the catalytic mechanisms of metalloenzymes. He then grew a profound appreciation for FT EPR and expanded his EPR toolbox for his research endeavors. After completing his Ph.D., Alvaro joined Bruker in January of 2023 working as an Applications Scientist.Presenter: Dr. Sergey Shilov (Product Manager, &nbsp;Bruker Optics)Dr. Sergey V. Shilov is a Product Manager for North America at Bruker Optics. Sergey joined Bruker in 2001. He is responsible for the support and development of new applications for the Bruker research FTIR systems. He received his Ph.D. in 1992 from the Russian Academy of Sciences in Polymer Physics and his M.S. from St. Petersburg State University (Russia) in Physics in 1986. Alexander Von Humboldt Foundation (Germany) awarded him a research fellowship in 1996. Sergey published 37 papers in peer-reviewed journals. His research interests include time-resolved FTIR spectroscopy, surface science, polymer, and life-science applications.&nbsp;</blockquote></div>

Bruker: Understanding Polymer Reactions and Degradation with FT-IR and EPR Spectroscopy

Understanding Polymer Reactions and Degradation with FT-IR and EPR Spectroscopy

Use FT-IR and EPR to study polymer curing, reaction kinetics, and radical mechanisms in polymerization and degradation.

Polymer Reactions with FT-IR and EPR Spectroscopy

Raman microscopy is widely used for chemical identification and chemical imaging, yet many real-world organic samples remain difficult to analyze with Raman. Biological tissues, cells, and environmental microplastic samples often exhibit strong fluorescence backgrounds, while weak scattering limits sensitivity. This can lead to researchers frequently encountering long acquisition times, uncertain particle identification, or datasets that lack the quality needed for confident interpretation and identification.Infrared spectroscopy is a powerful technique for chemical identification of organic samples but it has poor spatial resolution compared to Raman, tied to its much larger wavelengths. This webinar will discuss a breakthrough new sub-500nm IR spectroscopy technique called Optical photothermal IR spectroscopy (O-PTIR). O-PTIR provides chemical imaging and spectroscopy without fluorescence interference in seconds on organic samples such as microplastics and life sciences.This webinar will also discuss examples of simultaneous sub-micron IR and Raman spectroscopy, from the same sample region, such that the complementarity of IR and Raman without fluorescence interference in seconds as well as new laser-scanning based innovations for high-speed imaging for improved throughput. Application examples in microplastics characterization and life science research will demonstrate how challenging samples can be analyzed more reliably, how chemical specificity can be improved, and how multimodal workflows can provide actionable chemical information where traditional Raman imaging struggles.<h5>Key Learning Objectives:</h5><ul><li>Understand the fundamental limitations of Raman microscopy when analyzing samples such as microplastics and life science.</li><li>Learn about the new breakthrough O-PTIR technique that allows one to get sub-500nm spectra on organic samples with examples provided from microplastics and life sciences.</li><li>Discover how a combination of IR and Raman spectra obtained simultaneously and from the same sample location, can improve confidence in unknowns identification and provided, and also improved data quality.</li></ul><h5>Who Should Attend:</h5><ul><li>Microplastics and environmental researchers studying polymer particles in complex matrices</li><li>Cell and tissue biologists using chemical imaging or microscopy techniques</li><li>Biopharmaceutical scientists investigating subvisible protein particles, aggregates, and formulation stability</li><li>Raman microscopy and spectroscopy users encountering fluorescence or weak signal limitations</li><li>Polymer and materials scientists performing particle or surface characterization</li><li>Analytical chemists working with heterogeneous or challenging samples</li><li>Core facility managers and laboratory directors responsible for analytical instrumentation selection</li></ul><blockquote>Presenter: Andrew P. Ault (Professor, Department of Chemistry, University of Michigan)Presenter:&nbsp;Dr. Mustafa Kansiz (Director of Product Management, Photothermal Spectroscopy Corp)</blockquote>

C&EN: Overcoming Raman Microscopy Challenges in Microplastics and Life Sciences

Overcoming Raman Microscopy Challenges in Microplastics and Life Sciences

Webinar on O-PTIR spectroscopy combining sub-micron IR and Raman for microplastics, life sciences, and fluorescence-limited samples.

Raman Microscopy in Microplastics and Life Sciences

The aromatic profile of Trigonella caerulea (blue fenugreek) develops predominantly after harvest, yet its detailed chemical characterization has long been limited by analytical challenges associated with highly volatile and low-abundance compounds. In this study, conventional GC–MS headspace analysis was complemented by high-resolution GC–MS employing cyanopropyl-functionalized stationary phases to improve compound separation and identification.While standard GC–MS enabled the detection of major volatile aldehydes and monoterpenoids, high-resolution GC–MS proved essential for resolving co-eluting compounds and identifying very volatile aroma constituents with greater confidence. In parallel, non-volatile α-keto acids were quantified by LC–MS to provide a comprehensive view of aroma precursors.Comparative analysis demonstrates that high-resolution GC–MS significantly enhances analytical depth and accuracy, allowing a more complete understanding of aroma formation dynamics during drying and storage. These results underline the critical role of advanced chromatographic techniques in elucidating complex herbal aroma systems.<h4>Learning points:</h4><ul><li>Analytical resolution matters: High-resolution GC–MS provides superior chromatographic separation and compound identification compared to conventional GC–MS, enabling reliable detection of highly volatile and low-abundance aroma compounds that would otherwise remain unresolved.</li><li>Method choice shapes interpretation: The apparent aromatic profile of Trigonella caerulea depends strongly on the analytical technology used, with advanced GC–MS approaches revealing a substantially higher chemical complexity than standard methods.</li><li>Integrated analytics are essential: Combining high-resolution GC–MS for volatile compounds with LC–MS for non-volatile aroma precursors allows a more complete understanding of aroma formation dynamics during drying and storage.</li></ul><h4>Who should attend?</h4><ul><li>Analytical chemists and method developers&nbsp;</li><li>Food, flavor, and fragrance scientists&nbsp;</li><li>Natural products and phytochemistry researchers&nbsp;</li></ul>If you cannot attend this webinar please register to receive a link to the On Demand version the following day.<blockquote>Presenter: Dr. Thomas Stegemann (Lab Manager and group leader, Christian-Alberts-University Kiel)Thomas has a Dr. in pharmacy, deep GC and GC/MS knowledge and combines both assets working for the University in cooperation with Pharma companiesPresenter:&nbsp;Petra Gerhards (Regional Marketing Manager, EMEA, AAT, Thermo Fisher Scientific)</blockquote>

Thermo Fisher Scientific: Aromatic profiling using GCMS and HRGCMS

Aromatic profiling using GCMS and HRGCMS

Learn how HRMS GC–MS and LC–MS improve characterization of blue fenugreek aroma compounds and reveal complex flavor formation during drying and storage.

<h4>Topic 1: Trace and Ultra Trace levels of Micro Nano Plastics using Py-GCMS (20 minutes)</h4>Pyrolysis–GC/MS is increasingly demonstrating its capabilities for mass-based analysis of micro and nano-plastics. This seminar aims to provide an overview of the Pyrolysis–GC/MS technique and explain its application for the direct analysis of micro- and nano-plastics from various environmental matrices, enabling both identification and quantification.<h4>Topic 2: Advancing Trace-Level Chemical Analysis with the Agilent 5977C GC/MSD: Sensitivity, Stability, and Smart Performance for Modern Laboratories (20 minutes)</h4>As analytical laboratories face increasing pressure to deliver faster results, lower detection limits, and greater operational efficiency, choosing the right GC/MS platform has never been more critical. The Agilent 5977C GC/MSD represents the latest evolution in single quadrupole mass spectrometry, delivering enhancements that directly address today’s analytical challenges—whether in environmental testing, materials analysis, food safety, or industrial applications.In this webinar, we will introduce the key capabilities of the Agilent 5977C GC/MSD, including advanced ion source technologies, improved robustness and system intelligence, and workflow-friendly software tools that support confident, reproducible quantification.<blockquote>Presenter: Dr. Sathrugnan Karthikeyan (Regional Technical Manager, Frontier Laboratories, Japan)Dr. Sathrugnan Karthikeyan received his Ph.D. in Analytical Chemistry and did postdoctoral research in the USA, Japan, and Singapore universities. He has over 20 years of experience in analytical chemistry, food, and environmental safety fields of research. He is currently working as the Regional Technical Manager for Frontier Laboratories, JapanPresenter:&nbsp;Dr. Shruthi Kini (GC/GCMS Product Specialist, Agilent Technologies, Singapore)Dr. Shruthi Kini holds a Ph.D. from Nanyang Technological University, Singapore. She first gained experience with Agilent’s instruments as a customer before joining Agilent in 2021. Shruthi currently serves as a Product Specialist for GC and GC/MS solutions, supporting Singapore and South Asia.Originally a Research Scientist, she has in-depth knowledge of Agilent’s GC and GC/MS systems, with expertise in method development, method transfer, and validation for a wide range of analytical samples, including flavor compounds, edible oils, microbial, and clinical samples.</blockquote>

Agilent Technologies: Trace the Threat: Py-GC/MS Workflows for Microplastics Characterization

Trace the Threat: Py-GC/MS Workflows for Microplastics Characterization

Py-GC/MS and the Agilent 5977C GC/MSD improve trace analysis of microplastics and chemicals.

Py-GC/MS Workflows for Microplastics Characterization

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div>Looking to further elevate your Thermo Scientific Chromeleon CDS skills? Want to learn more about the administration tools for your Chromeleon software setup? Already attended <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5981">Administration Console I webinar (tips, shortcuts, and user/access management)</a>? Part II is the next step – focused on system-level management, structured resources, and automation across your Chromeleon software environment.In this practical session, we’ll dive into more Administration Console capabilities that help you manage and standardize your setup at scale – from Data Vault configuration and Chromeleon Resources to eWorkflows and automated rollout of updates. You’ll leave with proven approaches for keeping multi-station environments consistent, controlled, and easier to support.<h4>What’s different in Part II (vs. <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinar/5981">Part I</a>):</h4><ul><li>Beyond users &amp; permissions: Shift from access management to managing Chromeleon Resources and system components.</li><li>System structure &amp; governance: Learn how Data Vaults support secure, controlled data handling and standardized operations.</li><li>Remote administration: Explore methods for remotely updating Chromeleon Stations and reducing manual touchpoints.</li><li>Real-world best practices: Practical guidance to help maintain stability, security, and compliance as environments grow.</li></ul><h4>Who should attend:</h4>This session is designed for anyone wanting to learn more about administration of Chromeleon CDS, administrators, lab IT/support teams, and power users who want to take on administration responsibilities – especially those supporting multiple stations or managing standardized deployments.Get practical, immediately usable techniques to keep your Chromeleon software setup scalable, consistent, and supportable – with less manual effort and fewer surprises.Cannot attend the broadcast on March 26? Please register anyway to automatically receive the link to the recording.<blockquote>Presenter: Pascal Bächli (Sr. Engineer, Field Applications • Analytical Instrruments Group, Thermo Fisher Scientific)Pascal Bächli is a Sr. Field Application Engineer at Thermo Fisher Scientific with over 12 years of laboratory experience in both GMP and non-GMP environments. He specializes in the administration, implementation, and support of laboratory data systems, including Thermo Scientific Chromeleon CDS and Waters Empower. He supports networked Chromeleon software installations, delivering consulting and user training, and troubleshooting for complex technical and workflow issues.Pascal also holds a degree in Business IT, complementing his strong lab background and scientific expertise with deep knowledge of digital systems and business processes. This combination allows him to bridge the gap between the practical challenges scientists face and available technology to deliver efficient and compliant laboratory data solutions.</blockquote></div></div></div>

Thermo Fisher Scientific: Chromeleon Admin Console II: System management and automation

Chromeleon Admin Console II: System management and automation

In this practical session, we’ll dive into more Administration Console capabilities that help you manage and standardize your setup at scale

Chromeleon Admin Console II: System management & automation

Detecting gas leaks quickly and accurately is essential for safe operations, regulatory compliance, and emissions reduction. Optical gas imaging (OGI) cameras are an outstanding technology for assessing potential leaks in complex or potentially hazardous settings.In this webinar, Thermo Fisher Scientific and Opgal experts will discuss the benefits of handheld OGI cameras for real-time visualization of gas leaks in oil &amp; gas and industrial environments. The session will highlight how solutions such as the Opgal EyeCGas Multi, CO, CO₂, and long-range cameras enable faster inspections, improved leak detection efficiency, and safer, non-intrusive monitoring to support LDAR programs and methane reduction initiatives.<h4>The webinar will cover these key topics and more:</h4><ul><li>How handheld optical gas imaging works and where it adds the most value</li><li>Key advantages of handheld OGI compared to traditional leak detection methods</li><li>Typical applications for methane, CO, and CO₂ detection</li><li>How OGI supports LDAR, safety, and emissions compliance programs</li><li>Practical considerations when selecting a handheld OGI camera</li></ul><blockquote>Presenter: Bob GallagherBob Gallagher joined Thermo Fisher Scientific as the Product Line Manager for the Industrial Hygiene Strategy at the end of 2017. &nbsp;Bob has over 35 years of experience in Engineering and Product Management roles in the area of LDAR, site remediation, dust monitoring and other various industrial applications. &nbsp;Over Bob’s career, he’s worked for various technical companies such as Texas Instruments and Pentair and has successfully launched several innovative global products. &nbsp;Bob has a BS in Materials Science &amp; Engineering from Penn State University and an MBA from Boston University.Presenter: Michael TsudikovMichael Tsudikov is the Global Sales Director at Opgal, a Gevasol company, where he leads global sales and business development for advanced thermal and optical gas imaging solutions. He brings over seven years of experience driving growth through strategic partnerships, market expansion, and customer-focused sales initiatives. With a background spanning highly regulated industries and international markets, Michael is skilled at aligning innovative technologies with real-world operational and compliance needs. He is passionate about collaboration, innovation, and delivering high-quality solutions that create meaningful impact across industrial and environmental applications.</blockquote>

Thermo Fisher Scientific: Seeing Gas Leaks in Real Time: How Handheld Optical Gas Imaging Improves LDAR

Seeing Gas Leaks in Real Time: How Handheld Optical Gas Imaging Improves LDAR

Thermo Fisher Scientific and Opgal experts will discuss the benefits of handheld OGI cameras for real-time visualization of gas leaks in oil & gas.

 Handheld Optical Gas Imaging Improves LDAR

Comprehensive nanoscale characterization of 2D materials using AFM Characterizing 2D materials involves examining a wide range of nanoscale structures, properties, and chemistry. Atomic force microscopy (AFM) is extremely versatile, making it ideal for addressing these complexities. With AFM, researchers can investigate various aspects of 2D materials (often simultaneously), gaining detailed insights that are essential for advanced applications.<h4>Webinar Summary</h4>AFM plays a pivotal role in the nanoscale characterization of 2D materials by providing high-resolution topographical, mechanical, and electrical property mapping at the nanoscale, down to the atomic level. Identifying and characterizing single layers and multilayers is routine, while crystal orientation can often be determined with the proper choice of mode and probe. Since the AFM probe can act as a nanoscale electrode, it is possible to directly measure electrical properties of these materials at the relevant length scales between 1 and 100 nm. Photothermal AFM-IR (AFM-IR) adds localized chemical identification with nanometer scale spatial mapping by integrating infrared spectroscopy with AFM. Together, these capabilities correlate structure and chemistry, enabling comprehensive studies of complex 2D material systems. The AFM probe can also be used for nanomanipulation and nanolithography, allowing device fabrication by cutting, folding, or oxidation.<h5>In this webinar, we discuss:</h5><ul><li>Commonly used AFM modes for identification and characterization of 2D materials</li><li>Recent advancements in consistency of high-resolution 2D material mapping</li><li>Characterization of nanoelectrical properties in 2D materials through conductivity, impedance, and surface potential measurements</li><li>Nanoscale chemical identification through AFM-IR spectroscopy and mapping</li><li>Nanolithography on 2D materials, for example by tip-induced local anodic oxidation</li></ul><blockquote>Speaker:&nbsp;Bede Pittenger, Ph.D., Sr. Staff Development Scientist, AFM Applications, Bruker Nano SurfacesDr. Bede Pittenger is a Senior Staff Development Scientist in the AFM Unit of Bruker's Nano Surfaces Business. &nbsp;He received his PhD in Physics from the University of Washington (Seattle, WA) in 2000, but has worked with scanning probe microscopes for 25 years, building systems, developing techniques, and studying properties of materials at the nanoscale. &nbsp;His work includes more than thirty publications and three patents on various techniques and applications of scanning probe microscopy. &nbsp;Dr. Pittenger's interests span topics from interfacial melting of ice, to mechanobiology of cells and tissues, to the nanomechanics of polymers and composites.Speaker:&nbsp;Ming Ye, Ph.D., Applications Scientist, BrukerMing Ye earned his Ph.D. in chemistry from the Chinese Academy of Sciences and has more than 15 years of BioAFM experience.Speaker:&nbsp;Peter De Wolf, Ph.D., Director of Technology &amp; Application DevelopmentPeter De Wolf is director for AFM technology &amp; application development at Bruker Nano Surfaces, covering all applications related to Scanning Probe Microscopy (SPM). He obtained his PhD from IMEC, Belgium on the development of new SPM methods for 2D carrier profiling in semiconductors and has more than 25 years of experience on SPM. He is the author and co-author of over 30 publications related to electrical characterization using SPM. He also owns several SPM patents, and developed several new SPM modes for electrical characterization.</blockquote>

Bruker: Advances in AFM for the Characterization of 2D Materials

Advances in AFM for the Characterization of 2D Materials

AFM webinar on nanoscale characterization of 2D materials, including AFM-IR, electrical mapping, and nanolithography.

Experience how Agilent’s Gas Analyzers and Micro GC platforms deliver dependable, high‑efficiency gas analysis across the chemical and energy value chain.This three‑part webinar series offers market perspectives, expert technical guidance, and practical workflows designed to help laboratories enhance operational agility and performance.<h5>Webinar Series Details</h5><ul><li>Register once to attend the complete 3-part series</li><li>Submit your questions beforehand</li><li>Access recorded sessions anytime within one year</li><li>Certificate of attendance will be provided to all attendees</li><li>APAC-wide: 11:30 a.m. IST | 1:00 p.m. ICT | 2:00 p.m. SGT | 5:00 p.m. AEST</li></ul><h4>Part 1: Mastering Gas Sampling: Valve Fundamentals to ASTM Ready RGA &amp; TOGA Analysis</h4>In this session, learn how to achieve reliable permanent gas analysis, starting from proper valve selection and sampling fundamentals. This session covers analytical strategies for RGA, NGA, and TOGA using Agilent GC systems helping your lab improve accuracy, consistency, and ASTM‑aligned performance.<blockquote>Presenter: Mr. Praveen Arya (Application Engineer, Agilent Technologies)Presenter: Dr. Manoj Surwade (Product Specialist, Agilent Technologies)</blockquote>

Agilent Technologies: Agilent Gas Analyzers in the Chemical & Energy Market

Mastering Gas Sampling: Valve Fundamentals to ASTM Ready RGA & TOGA Analysis

In this session, learn how to achieve reliable permanent gas analysis, starting from proper valve selection and sampling fundamentals.

Mastering Gas Sampling: Valve Fundamentals & TOGA Analysis

Whether you are new to FTIR microscopy or looking to refine your existing workflows, this live webinar will provide practical guidance to help strengthen your analytical approach. We will explore key considerations in measurement modes, sample preparation, method optimization and data interpretation—focused on helping you generate clear, reliable results across a range of applications.Through real-world examples and applied strategies, we will discuss how to select appropriate measurement techniques, optimize parameters for improved spectral quality and address common analysis challenges. Our goal is to support you in building confidence when working with complex or heterogeneous samples.<h5>You will learn:</h5><ul><li>Transmission, reflectance or micro-ATR—how to determine an appropriate mode for your sample</li><li>Practical considerations for microscopy sample preparation and handling</li><li>Approaches to optimizing measurement parameters for improved spectral quality</li><li>Library matching strategies to address common interpretation challenges</li><li>Tips for analyzing complex and multi-layered materials</li></ul><blockquote>Presenter: Suja Sukumaran, PhDSuja Sukumaran, Ph.D., is a Product Manager at Thermo Fisher Scientific. She received her Ph.D. in Biophysics from Johann Wolfgang Goethe University, Germany, as part of the International Max Planck Research School. She has expertise and extensive experience in molecular spectroscopy, visible and fluorescence Imaging, and protein and lipid biochemistry. Her current research interests are AI for protein folding, microplastics, and polymer recycling.</blockquote>

Thermo Scientific: FTIR microscopy: Practical guidance for effective sample analysis

FTIR microscopy: Practical guidance for effective sample analysis

Live webinar on FTIR microscopy workflows: measurement modes, sample preparation, optimization and data interpretation for reliable analytical results.

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