Join us for a free two-day LECO Separation Science Workshop on September 23–24, 2026, at the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/219">C³AL Laboratory</a> at Cal State LA. Registration is free, and meals and refreshments will be provided throughout the workshop.&nbsp;<h4>Registration</h4><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=iYeNbqIuykW7qZP4_jUEVbznDB40eK1PgjPzhHyb__9URTFTTFA5UEEzQ1A4MUtFV0o4TEJTNlZCOS4u&amp;route=shorturl">Register HERE</a>Space is limited, register today!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg" alt="LECO: LECO Separation Science Workshop - QR code for registration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg 156w," sizes="100vw" width="437" height="437"></blockquote><h4>Hand-on Experience with the LECO Complex Chemical Composition Analysis Lab C3AL</h4><ul><li>Work directly with LECO instruments in the C3AL Laboratory</li><li>Learn complete analytical workflows from sample to answer</li><li>Get expert guidance from LECO application scientists</li><li>Develop methods and solve real-world challenges</li><li>Collaborate, ask questions, and build your skills</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg" alt="Cal State LA: The LECO Pegasus BTX system in Cal State LA’s LECO Complex Chemical Compositional Analysis Lab enhances research and student training in advanced chemical analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg 227w," sizes="100vw" width="1252" height="863">The first day will focus on the fundamentals and theory of comprehensive two-dimensional gas chromatography (GC×GC), with an emphasis on understanding how GC×GC can enhance your research, solve complex analytical challenges, and support your laboratory or company goals.&nbsp;The second day will be dedicated to hands-on activities, giving participants the opportunity to work directly with LECO instrumentation, learn practical analytical workflows, and analyze their own samples with guidance from LECO application scientists.&nbsp;Whether you are new to GC×GC or looking to expand its use in your research or organization, this workshop offers a unique opportunity to learn, explore, and apply the technology in a practical setting. Space is limited, so register early!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg" alt="Cal State LA: LECO QUADJET GCxGC coupled to Pegasus BT 4D TOM MS in the Complex Chemical Composition Analysis Lab (C³AL)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/thumbnail_Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg 234w," sizes="100vw" width="1949" height="1299">

LECO Separation Science Workshop

An international research team, which included scientists from the Faculty of Science at Palacký University and the Institute of Physics of the Czech Academy of Sciences, has succeeded in unraveling the complex mechanism by which a chemical bond is formed during a collision between molecules. The experts found that the reaction only takes place if the molecules are oriented towards each other within a very narrow range of angles – within the so-called cone of reaction. This joint research has thus provided an answer to one of the fundamental questions of chemistry: under what conditions do chemical bonds form between molecules. The results of the study&nbsp;Spatially resolving the cone of reaction for a single molecule&nbsp;were published in the prestigious scientific journal&nbsp;Science.Many chemical reactions begin with the collision of two particles. However, for a new chemical bond to form, it is not enough for the molecules simply to come into contact. Their collision must occur with sufficient energy, in the correct relative orientation and at the right location. Under normal conditions, such as in solutions or gases, molecules collide chaotically, and the precise parameters of these collisions cannot therefore be controlled.<h4>Molecules under control</h4>Scientists were able to control the collisions of individual molecules on a copper surface and monitored the process using a scanning tunnelling microscope. They used the instrument not only to visualise individual molecules, but also to deliberately accelerate the reactants towards one another. They subsequently analysed each collision with atomic-level resolution. This enabled them to determine unequivocally whether a new chemical bond had formed between the molecules.<h5>“What is hidden in the statistics of billions of collisions in conventional chemistry, we have managed to break down into individual cases and map directly.” Adam Matěj</h5>A key finding of the study is that the outcome of a collision is determined by the extremely precise orientation of the molecules. A new bond was formed only when the target molecule was oriented within a few degrees of the direction of movement of the other molecule. When rotated by more than fifteen degrees, the molecules simply bounced off each other without any reaction.<h4>The precise orientation of the molecules is crucial</h4>“For the first time, we were able to observe, using a single molecule, exactly how precisely it must be oriented for the reaction to take place at all. What is hidden in the statistics of billions of collisions in conventional chemistry, we have managed to break down into individual cases and map directly,” said Adam Matěj from the Department of Physical Chemistry at the Faculty of Science.The theoretical part of the study, in which researchers from Palacký University and the Institute of Physics of the Czech Academy of Sciences were involved, played a significant role. Using quantum-mechanical calculations, they explained why the ‘reaction cone’ is so narrow. It turned out that the reactive carbon atom is surrounded by hydrogen atoms, which block the access of the reacting molecule from almost all directions.<h4>The arrangement of atoms restricts access to the reaction</h4>The calculations also shed light on a surprising experimental result. The chemical reaction took place even when the molecule moved along an adjacent row of copper atoms, where, according to the original assumptions, no bond should have formed.<h5>“The strength of this work lies in the fact that the experiment and theory have been brought together into a single picture. The microscope showed what happens during the collision, and the calculations explained why.” Pavel Jelínek</h5>“The explanation lies in the slight displacement of a single copper atom on the surface. The target’s bond to the surface pulls it out of its position and brings it close enough to the neighbouring row that it can literally take over the projectile and direct it to the correct spot. This shows that the surface is not merely a passive substrate, but actively participates in the reaction itself and can even facilitate pathways that would otherwise be unfavourable,” noted Adam Matěj.<h4>The surface also determines the course of the reaction</h4>The results are significant for the development of so-called surface reactions, in which new materials and nanostructures are purposefully assembled from individual molecules. A better understanding of the influence of the spatial arrangement of molecules will enable the design of molecular building blocks so that they bond more reliably and efficiently. This represents an important step towards the development of technologies based on the controlled construction of structures atom by atom.“The strength of this work lies in the fact that experiment and theory have been brought together into a single picture. The microscope showed what happens during the collision, and the calculations explained why. Without a theoretical model, we would have found it difficult to discover that the movement of a single surface atom is behind the unexpected course of the reaction,” added Pavel Jelínek from the Institute of Physics of the Czech Academy of Sciences.<blockquote>The study&nbsp;Spatially resolving the cone of reaction for a single molecule&nbsp;was produced in collaboration between researchers from the University of Graz, the Institute of Physics of the Czech Academy of Sciences, Palacký University in Olomouc, Charles University and Humboldt University in Berlin.</blockquote>

Scientists reveal when chemical bonds form in molecular collisions 

Injecting water into a gas chromatography (GC) system has always raised concerns for analysts. Many wonder if water will damage their <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products?category=7&amp;manufacturerItems=50">GC column</a> or instrument. In fact, one of the most common questions in gas chromatography water analysis is whether aqueous samples can be safely introduced without compromising results.Selecting the right GC column for water analysis and following proper injection techniques can minimize the risk of column damage and maintain reliable analytical results.<h3>Why Water Injections Are Risky in GC</h3>Water injections in gas chromatography columns are risky due to the following reasons:<h4>Backflash Issues</h4>Water expands significantly when vaporized at high inlet temperatures (e.g., 250–300 °C). If the expansion volume exceeds the inlet liner capacity, backflash can occur. This contaminates injector parts, leaving residues that cause ghost peaks, carryover, sample loss, and elevated baselines, ultimately reducing reproducibility and accuracy.<h4>Stationary Phase Degradation</h4>As a highly polar solvent, water can hydrogen bond with stationary phase polymers such as polyethylene glycol (PEG) or wax phases. Repeated exposure alters selectivity, shifts retention times, and may increase bleed in non-crosslinked phases. While older immobilized PEG phases are especially vulnerable, modern chemically bonded and crosslinked stationary phases offer improved resistance, making them more suitable to inject up to 100% water samples.<h4>Incomplete Vaporization</h4>Water’s high boiling point and poor wetting of non-polar stationary phases can result in incomplete vaporization. This may lead to peak splitting, band broadening, or reduced sensitivity. For this reason, injection settings need to be finely adjusted to avoid these effects.<h4>Detector Issue</h4>Standard GC detectors do not directly detect water. Excess water injected into a flame ionization detector (FID) can quench or even extinguish the flame, while moisture in an electron capture detector (ECD) can interfere with electron capture efficiency, suppressing signals or causing false responses.<h3>Choosing the Right GC Columns for Water-Containing Samples</h3>Here are some strategies that can help you increase the life of GC columns when analyzing water-containing samples.<ul><li>Use of cross-linked phases: Modern stationary phase design has greatly improved tolerance to water injections in GC. Cross-linking chemically bonds the stationary phase to the silica surface, making it far more resistant to leaching or washout from polar solvents. Traditionally immobilized but not cross-linked phases were much more vulnerable to degradation. For example, polyethylene glycol (PEG) phases are inherently hydrophilic and prone to water damage unless cross-linked. With technologies such as engineered self-crosslinking (ESC), used in Phenomenex <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1571">Zebron ZB-WAXplus GC columns</a>, PEG phases can withstand repeated water injections without significant loss of efficiency.</li><li>Use of non-polar columns: Non-polar bonded and cross-linked columns (e.g., PDMS phases) are inherently resistant to water damage, though incomplete vaporization may still affect peak quality.</li></ul><h3>Tips to Protect Your GC System from Water Damage</h3>Implementing a few key tips can help protect your GC system from water damage. Here are some of the important recommendations:<ul><li>Keep injections small: Limit water injections to ≤0.2 µL to minimize backflash and protect the stationary phase.</li><li>Select the right liner: Use an appropriately sized inlet liner (e.g., 4.0 mm ID tapered or with a double gooseneck) to reduce backflash. A deactivated glass wool plug can promote rapid vaporization, though it may not be suitable for all analytes.</li><li>Reduce syringe carryover: Rinse syringes with a 50:50 methanol–water mixture between injections. In some methods, preparing samples with a small percentage of methanol can improve reproducibility and syringe performance.</li><li>Optimize solvent and injector conditions: Limit water injections to ≤0.2 µL to minimize backflash and protect the stationary phase.</li><li>Adjust carrier gas conditions: Ensure your <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/article/5538">gas chromatography injector setup</a> is correct to prevent water buildup. Combining water with a lower-expansion solvent (e.g., methanol) and maintaining an optimized injector temperature helps improve vaporization while limiting expansion.</li><li>Maintain a clean carrier gas supply: Replace gas cylinders before they are nearly empty to avoid backflow or moisture intrusion into the system While injecting water into a GC system is not simple and ideal, it can be managed safely with the right precautions. By choosing the appropriate stationary phase, following proper GC injector setup, and maintaining your instrument, you can conduct gas chromatography water analysis with confidence. For more information on GC hardware and maintenance, explore the <a target="_blank" rel="noopener noreferrer" href="https://www.phenomenex.com/resources/knowledge-center/gc-knowledge-center/understanding-the-essential-components-of-gas-chromatography">key parts of a GC instrument</a>.</li></ul>

Water Injections in GC: Is it Safe?

Article

Events

Academy

Science and research

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

Phenomenex

In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

LECO

Palacký University Olomouc (UP) is an internationally respected and scientifically and academically highly productive university in Central Europe. Founded 22 December 1573, it is the second-oldest university in the Czech Republic and the oldest one in Moravia. For 450 years it has contributed to the intellectual wealth of society and to its scientific, cultural, and social development.

Palacký University Olomouc

Separation Science

Agilent Technologies

PerkinElmer

Restek Corporation

C&EN

Shimadzu Corporation

Chromatographic Methods to Speed Up Your Analysis and Increase Your Throughput: A review of chromatography theory with a focus on using principles of chromatography to make your analysis more efficient and cost effective.
We will also review the Agilent software tools available to help with column selection and GC method conditions.
<blockquote>
Presenter: Shannon Coleman (GC Application Scientist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Shannon Coleman holds a B.S. degree in Chemistry from the University of Colorado and an M.S. in Chemistry from Emory University. He is currently a GC Application Scientist at Agilent. He has been working with multidimensional and valve gas chromatography across various industries for the past 20 years. He supports Agilent’s North America Field Organization and spends his time consulting with and delivering educational content on understanding the fundamentals of chromatography and understanding complex gas chromatography analysis to Agilent’s customers.
</blockquote>

Agilent Technologies: Chromatographic Methods to Speed Up Your Analysis and Increase Your Throughput

Chromatographic Methods to Speed Up Your Analysis and Increase Your Throughput

Analysis for ethanol and other volatiles in blood has traditionally been performed by Gas Chromatography with Flame Ionization detection (GC-FID). This technique has excellent quantitative accuracy, but the flame ionization detector provides no molecular or structural information (apart from the existence of C-C bonds). Structure specific information is helpful in ruling out co-elution and to verify the identity of the chromatographic peak. Vacuum ultraviolet (VUV) absorption spectroscopy can provide this sort of informative detection.
VUV detectors specifically designed for GC are commercially available and provide important benefits to blood alcohol analysis, such as verification of peak purity, facile deconvolution of coeluting peaks, and calibration based on Beer–Lambert law and molar absorptivity of the analyte. Since molar absorptivity is an inherent constant property of a molecule, calibration is straightforward and stable.
<blockquote>
Presenter: Alan Gallapsy (Field Application Scientist, PerkinElmer)
</blockquote>

PerkinElmer: Vacuum Ultraviolet Detection of Blood Volatiles

Vacuum Ultraviolet Detection of Blood Volatiles

<blockquote>
Presenter: Tom Mancuso (Product Specialist, PerkinElmer)
</blockquote>

PerkinElmer: Detectors for GC Analysis of Ethanol in Blood

Detectors for GC Analysis of Ethanol in Blood

<blockquote>
Presenter: Lee Marotta (Principal Field Application Scientist, PerkinElmer)
</blockquote>
<blockquote>
Lee Marotta started her career in gas chromatography at Exxon Corporate Research in 1988. In 1992, Lee moved onto PerkinElmer developing methods and helping people in all industries that require gas chromatography including headspace, thermal desorption and mass spectrometry. With 32 years experience in all fields of gas chromatography, Lee feels her main role is to help people be successful
</blockquote>

GC Tips and Tricks

Have you ever had a question about your GC/GCMS analysis and thought, &quot;I have no idea what to do,&quot; or that because the question seemed so simple, everyone must already know the answer and &quot;I’m the only one who doesn’t know what to do.&quot; We can assure you that you are not alone.
If you have a question, we can guarantee that you are not the first... nor the last person to ask it. Sometimes the simplest of questions can have the most complex answers. A question about which liner to use can lead to a discussion on the benefits of glass wool versus glass frits. A question about how long a column should last may trigger a discussion about the importance of a leak free system, the maximum temperature limit, proper phase selection, and how an application may benefit from using backflush.
There’s no such thing as an easy answer, because the answer always depends on many different factors. Therefore, we have complied a list of some of our most frequently asked questions, which may seem like simple questions, but in reality they have anything but simple answers.
Why not submit your question to us in advance when you register for the webinar.
<h3>By attending this webinar you will learn:</h3>
<ul>
<li>best practices with GC and GC/MS systems – from liner and column selection to why gas filters matter and instrument prep recommendations, and</li>
<li>why there is not always an easy answer to most GC(MS) questions</li>
</ul>
<h3>Why should you attend?</h3>
To gain more understanding on why different consumables are used for different applications, and listen to Agilent Scientists discuss the complexities of the most frequently asked questions they receive.
<blockquote>
Presenter: Angie Smith-Henry (Applications Chemist for GC and MS Supplies, Agilent)
</blockquote>
<blockquote>
Angie is is an applications chemist for GC and MS Supplies at Agilent in Wilmington, Delaware, USA. Previously, she was an applications chemist for the MSD Solutions and Applications group with a focus on developing analysers and applications for energy, chemical and environmental markets. Angie holds a PhD in Physical Chemistry from Lehigh University and BS in Chemistry from Juniata College.
</blockquote>
<blockquote>
Presenter: Vanessa Abercrombie (Gas Chromatography Applications Chemist, Agilent)
</blockquote>
<blockquote>
Vanessa is a GC Applications Chemist at Agilent in Folsom, California, USA. Vanessa has a broad background in GC and GC/MS, including experience as an instrument chemist at Bode Technology in Virginia working under contract to the FBI’s Laboratory Division. Prior to that, Vanessa worked for ETS Labs in St. Helena, California as an Analytical Chemist where she researched and developed quantitative separations by GC/MS and UHPLC for beer, wine, and spirits. She holds a Master of Forensic Science from The George Washington University and a Bachelor of Arts in Chemistry from Sonoma State University.
</blockquote>
<blockquote>
Moderator: Diane Turner (Director &amp; Senior Consultant, Anthias Consulting)
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<blockquote>
Diane Turner is Director and Senior Consultant of Anthias Consulting in Cambridgeshire, UK. A Warwick University graduate, Diane completed her masters in Analytical Chemistry and started her career in environmental chemistry, later gaining significant experience as an Applications Chemist. Diane’s area of research through her PhD studies at The Open University was disease diagnosis. She has developed methods for, and given support and training for companies in most industries around the world for more than 20 years. Diane also holds voluntary roles with The Royal Society of Chemistry and other scientific organisations.
</blockquote>

Pixabay/loufre: Ask the Agilent Experts: GC and GC/MS Scientists Answer Your Most Frequently Asked Questions

Ask the Agilent Experts: GC and GC/MS Scientists Answer Your Most Frequently Asked Questions

best practices with GC and GC/MS systems – from liner and column selection to why gas filters matter and instrument prep recommendations...

Agilent Experts: GC and GC/MS Scientists FAQ Answers

There a number of ways that the analysis time can be reduced. All depends on how well the components are separated in the present application.
<ul>
<li>Most easy is to trade in some resolution for speed using higher gas velocities or using a shorter column.</li>
<li>If the exact separation must be maintained, a choice has to be made between using hydrogen as carrier gas, or use a smaller ID capillary column (or a combination). </li>
<li>Important is that in the new method, the same chromatogram must be obtained. Using the EZGC method translator, you can simply calculate the oven program you need for that.</li>
</ul>
Also the ProEZGC chromatogram modeler, you can see the impact of any changed parameter, using your computer.
<blockquote>
Presenter: Jaap de Zeeuw (Gas Chromatography Specialist, Restek)
</blockquote>
<blockquote>
Jaap is a world-renowned chromatographer with over 40 years of experience, including 27 years with Varian/Chrompack focusing on industrial analysis challenges. For his 1979 graduation from The Institute for Higher Education, specialized in chemistry, Jaap authored a paper titled &quot;The Challenge of Coating Flexible Fused Silica Capillary Columns&quot; and has since distinguished himself as an authority on the subject. Directly involved with the creation of numerous chemically bonded columns, including the first bonded PEG column and the stabilized PLOT columns widely used in the petrochemical arena, Restek’s international GC specialist has helped develop new techniques, such as fast GC-MS using vacuum GC technology, and has filed two patents for his work. Based out of the Netherlands, Jaap celebrates 10 years with Restek. Jaap is extensively published and regularly travels internationally to share his knowledge.
</blockquote>

Restek: Reduction of analysis time in GC using existing instrumentation

Reduction of analysis time in GC using existing instrumentation

Higher gas velocities or using a shorter column? Using hydrogen as carrier gas, or use a smaller ID capillary column? Using the EZGC method translator?

Reduction of analysis time in GC

<h3>Learning objective:</h3>
<ul>
<li>Testing Detailed Hydrocarbon Analysis by ZB-DHA PONA COLUMN</li>
<li>How to improve Excellent Response and Peak Symmetry for Polar Oxygenates</li>
<li>Applications on DHA, PONA, PIONA, PIANO, and ASTM Methods - (D5134, D5441, D5501, D6729, D6730, D6733)</li>
</ul>
<blockquote>
Presenter: Rahela Banu (Business Development Manager, Phenomenex India)
</blockquote>
<blockquote>
Rahela Banu holds a master’s degree in Micro Biology from Osmania University. She worked as a Microbiologist in Royal life sciences doing analysis of FAME by Gas chromatography from various microbial samples. Later started working with Merck as Patient Support counselor. After successful 3 years stint with them she moved to Phenomenex.
</blockquote>
<blockquote>
She started as an Application specialist with Gas Chromatography; Being the sole person to handle GC technique entirely for 9 years, Rahela has gained vast experience in handling customer Applications/Inquiries catering to wide extended market segments. 
</blockquote>
<blockquote>
Rahela has traveled extensively through all parts of India reaching customers of various segments working with GC/HPLC/SPE technique as Industry Specialist; Having visited manufacturing plant of Phenomenex Torrance unit Rahela works very closely with GC developing team making a bridge between advanced technologies and customer applications. 
</blockquote>
<blockquote>
Currently she is working as a Business Development Manager at Phenomenex India and is responsible for Seminars/webinars/training&#39;s/Global coordination/market development in all product lines that goes into this applied market segment PAN India.
</blockquote>

Phenomenex: ASTM Methods for DHA, PONA, PIONA, PIANO with GC

ASTM Methods for DHA, PONA, PIONA, PIANO with GC

DHA by  ZB-DHA PONA COLUMN, Improve Polar Oxygenates and Applications on DHA, PONA, PIONA, PIANO, ASTM Methods (D5134, D5441, D5501, D6729, D6730, D6733).

Gas chromatography (GC) is considered a mature analytical technology with many critical industrial applications. Despite its maturity, the role of GC has not been diminished. Instead, its role continues to gain influence. Innovations that aid in widening the use of contemporary GC include: maintaining gas chromatographic performance without compromising affordability, enhanced data reliability between analysts, and precise digital pneumatic controls.
Join Dr. Ronda Gras and Dr. Alicia Stell as they discuss advancements in gas chromatography (GC) with novel system improvements that enable ease of use, even when operated by inexperienced operators. Since ease of use means nothing if the data is not meaningful, Drs. Gras and Stell will review applications in the petrochemical and chemical industries and determine if data is comparable to larger GC systems.
<h3>Key Learning Objectives:</h3>
<ul>
<li>Trends and recent developments of GC in industry </li>
<li>New column form factors with rapid column replacement capability </li>
<li>Relevant industrial petrochemical and chemical industry applications</li>
</ul>
<h3>Who Should Attend:</h3>
<ul>
<li>Laboratory managers </li>
<li>Chromatographers </li>
<li>New product developers</li>
</ul>
<blockquote>
Presenter: Ronda Gras, Ph.D. (Research Scientist of Analytical Science, Core R&amp;D of the Dow Chemical Company)
</blockquote>
<blockquote>
Presenter: Alicia Stell, Ph.D. (Lead R&amp;D Scientist, CEM Corporation)
</blockquote>
<blockquote>
Presenter: Jeff Huber (Contributing Editor, C&amp;EN Media Group)
</blockquote>

C&EN: Innovations and Developments in the Advancement of Gas Chromatography

Innovations and Developments in the Advancement of Gas Chromatography

<blockquote>
Presenter: Jaap de Zeeuw (Restek, Netherlands) 
</blockquote>
<blockquote>
Presenter: Jan Pschierer (Restek, Germany)
</blockquote>
<blockquote>
Presenter: Emanuele Ceccon (Restek, Italy)
</blockquote>
<a href="https://www.rafa2021.eu/vendor_webinars/nov_3/3_Nov%203_Restek_RAFA%202021_Vendor%20webinar.pdf">Presentation details</a>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Restek_Rafa_2021_New_Concepts_to_Speed_up_Pesticides_Residue_Analysis_1f441975ba/Restek-Rafa-2021-New-Concepts-to-Speed-up-Pesticides-Residue-Analysis.png" alt="Restek/Rafa 2021: New Concepts to Speed up Pesticides Residue Analysis.png"/>

Restek/RAFA 2021: New Concepts to Speed up Pesticides Residue Analysis

RAFA 2021: New Concepts to Speed up Pesticides Residue Analysis

The discussion on mineral oil hydrocarbons (MOH; divided into mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH) started already in the 1990’s when publications reported the possible migration from a food contact material into the packed good. The debate on those findings broadened afterwards and is continuing till today, dealing with the still remaining knowledge gaps of analysis, exposure assessment, hazard characterisation and risk assessment (1,2).
This talk will focus on mainly on the still present pitfalls of the analysis. Although there had been significant advancements, the analysis is still a huge challenge. There is a lack of validated and standardized analytical methods for the whole sample preparation procedure to allow generation of reliable occurrence data for the complex and highly variable matrix “food”. State-of-the-art analysis is done using the online-coupling of LC-GC-FID, but analysis reveals only unresolved humps with unknown origin. Therefore, confirmatory techniques using multi-dimensional chromatography, e.g. 2D-Comprehensvie GC×GC with various detector types, are used to allow for an adequate substance class identification, recognition of false-positive values and therefore correct quantification of the generated humps. Furthermore, toxicological studies on the identified individual substance classes are needed to fully understand and allow for the health risk assessment for consumers (3).
<blockquote>
Presenter: Andrea Hochegger (TU Graz, Institute of Analytical Chemistry and Food Chemistry, Graz, Austria)
</blockquote>

GCMS webinars focusing on GC - page 27