In the week of April 13, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4>👉 Search and filter in the largest global database with over 5 500 GC, LC, MS and spectroscopy webinars.</blockquote><div><div><div><div><div><div><h5>1. Agilent Technologies: The Journey of Safer Science through Safer Labs</h5><ul><li>Tu, 14.4.2026 07:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6104">Registration</a></li></ul>Agilent Safer Labs webinar highlights best practices in lab safety, including handling, storage, and instrumentation, helping professionals build safer, more efficient laboratory environments.<h5>2. Agilent Technologies: Column Confidence: Making the Right Choice for Your GC Needs</h5><ul><li>Tu, 14.4.2026 17:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/5725">Registration</a></li></ul>Learn how to choose the right GC or GC/MS column by understanding stationary phase chemistry and column dimensions. Improve selectivity, peak behavior, and resolution for a more robust analysis.<h5>3. Metrohm: Measure smarter, spend less – NIR spectroscopy for polymer analysis</h5><ul><li>Th, 16.4.2026 15:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6032">Registration</a></li></ul>Discover how NIR spectroscopy enables fast, chemical-free polymer analysis. Learn how manufacturers can streamline quality control, reduce waste, and improve efficiency with rapid multi-parameter measurements.<h5>4. C&amp;EN: Precision Lab Solutions for High-End Optics and Coatings</h5><ul><li>Th, 16.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6096">Registration</a></li></ul>Join this presentation and open discussion with industry-leading experts Patrick Muller and Kieran Evans – leaders in UV/Vis and IR analytical methods and testing techniques.</div></div></div></div></div></div>

Webinars LabRulezGCMS Week 16/2026

This study introduces atmospheric solids analysis probe high-resolution tandem mass spectrometry with cyclic ion mobility as a novel approach for characterizing Asian lacquers. Applied to 27 historical samples from Japan, China, Vietnam, and Myanmar, the method enabled classification by geographic origin based on phenol and benzenediol derivatives.In addition to lacquer identification, the technique simultaneously detected pigments such as arsenic sulfides and associated resins, providing comprehensive chemical insight. This approach expands analytical capabilities for cultural heritage studies, supporting restoration, conservation, and art historical research.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572">Characterization of Asian lacquers by atmospheric solids analysis probe high resolution tandem mass spectrometry coupled with cyclic ion mobility separation</a></h4>Vojtěch Zemek, Radek Ryšánek, Petra Krejčí, Lukáš Kučera, Jana Nádvorníková, Adéla Tůmová, Helena Heroldová, Adriana Stříbrná, Petr BednářJournal of Cultural Heritage, 77, 2026, 187-196<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.culher.2025.11.012">https://doi.org/10.1016/j.culher.2025.11.012</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.<div>In recent years, an expansion of ambient pressure ionization mass spectrometry in various areas is observed [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0024">24</a>,<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0025">25</a>]. Atmospheric solids analysis probe mass spectrometry (ASAP-MS) is a powerful technique for direct analysis of even very complex samples, such as polymers [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0026">26</a>], foods [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0027">27</a>], or petrochemical sources and products [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0024">24</a>]. ASAP ionization technique is a modification of atmospheric pressure chemical modification (APCI). In conventional arrangement, the sample is attached to a sampling probe tip (a standard melting point capillary is inserted into powder or liquid sample that sticks to its surface) and the probe is consequently placed into the ion source (commonly adapted ESI or APCI source). The analytes are released into the gas phase using hot gas (nitrogen) and ionized in the corona discharge. The formed ions (quasimolecular ions, radical cations or radical anions) are then transferred to the evacuated part of mass spectrometer [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0024">24</a>,<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0025">25</a>,<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0028">28</a>]. Note that especially at higher vaporization temperatures a portion of the analytes is pyrolyzed and a mixture of parent ions and pyrolysis product ions is commonly observed in the ASAP-MS spectra [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0029">29</a>]. The main feature of this direct MS mode is a fast detection of the formed products (including those with a higher mass and perhaps a shorter lifetime). In contrast, due to chromatographic separation in py-GC/MS, only relatively stable and volatile products are detected (the chromatographic step provides an additional selectivity here). In addition, electron impact ionization produces significantly different spectra profiles compared to the atmospheric pressure chemical ionization ongoing in the ASAP source. Both techniques are to a certain extent complementary [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0024">24</a>,<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0025">25</a>,<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0030">30</a>].There is a direct possibility of coupling mass spectrometry with ion mobility spectrometry (IMS) to significantly improve the selectivity of analysis (and, to certain extent, to compensate the advantage of the chromatographic step in py-GC/MS while maintaining the direct MS analysis speed). During an ion mobility spectrometry experiment, ions of analytes are flying through the ion mobility cell (e.g., a drift tube or a closed-loop path within a traveling wave ion guide in case of the cyclic ion mobility cell) filled with buffer gas (e.g. helium). In this process, ions collide with the buffer gas. These collisions slow down the ions differently based on their size, shape and charge. Ion mobility spectrometry therefore allows separation of the present analytes in the gas phase according to their collision cross sections (CCS). It also allows separation of isomeric compounds and filtration of the matrix signals, resulting in a higher quality of the MS and MS/MS spectra [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0031">[31]</a>, <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0032">[32]</a>, <a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0033">[33]</a>].ASAP-MS has a high potential for the study of protective and decorative layers on the surfaces of historical objects. To the best of our knowledge, however, ASAP-MS and ASAP-IMS-MS have never been used for characterization of lacquers. This paper deals with the development of ASAP-MS method for characterization of Asian lacquers and its application for classification of oriental historical objects.<h4>3. Material and methods</h4><h5>3.3. Instrumentation and experimental setup</h5>Analyses were performed using <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/202">Waters Cyclic IMS high resolution tandem mass spectrometer</a> with an integrated cyclic ion mobility cell and atmospheric solids analysis probe (ASAP) used as ion source (Waters, Milford, MA, USA). Samples (∼ 0.1–0.5 mg) were inserted into a melting point capillary (G119/32, manufacturer SAMCO, United Kingdom) through an in-lab radially drilled hole (hole diameter: approx. 1 mm; distance from the bottom end approximately 5 mm). Solution of 2′,4′,6′-trihydroxyacetophenone monohydrate (THAP) in acetone was used as a standard for lock mass correction (c = 1 mg.ml-1). The m/z values were calculated as the means from three repeated measurements of appropriate samples. Approx. 1 μl of standard was deposited onto the capillary using a small pipette tip. Following experimental parameters were used: desolvation temperature of 600 °C, source temperature of 100 °C, corona “current” mode (corona current 2.0 μA), cone voltage of 30 V, source offset of 10 V, cone gas flow of 30 l/min, desolvation gas flow of 500 l/min, nebulizer gas pressure of 6 bar and reference capillary voltage of 2.5 kV. As for the ion mobility separation setup, a cyclic ion mobility cell was used in the following sequence: 1. Inject (10 ms), 2. Separate (37 ms), 3. Inject to Pre-Store (0.50 ms), 4. Eject (0.50 ms), 5. Reinject from Pre-Store (0.63 ms), 6. Eject and Acquire (13.20 ms). TW static height was 11 V, TW ramp start height was 15 V and TW ramp end height was 35 V. Acquisition time was 3 min for the MS scan and 1 min for the MS/MS scan used for identification of analytes. In the MS/MS mode, collision energy 30 V was used for pentadecyl and heptadecylcatechols, 35 V for phenols substituted with (CH2)10C6H5 and 40 V for catechols substituted with (CH2)12C6H5 and phenols substituted with CH2CO(CH2)10C6H5, respectively. Scan time 1 s was used for both scans. At the end of each working day, sample V was measured for confirmation that the instrument measured consistently. Values of m/z were calculated by MassLynx software (version 4.2, SCN 1016) after lock mass correction using the signal of protonated molecule of THAP. Theoretical mass of particular analyte was used for lock mass correction in the MS/MS spectra. Centroid top at 80 % and areas of peaks were used for accurate mass and intensity of signals calculation. The maximal accepted difference from theoretical mass (dtm) of signals was 10 mDa. Peak areas were used to compare the abundance of identified analytes among particular samples. Mobilograms from cyclic ion mobility experiments were produced by DriftScope v2.9 software. In mobilograms, spectra were generated by integration at Full Width at Half Maximum (FWHM) of peaks at drift time 1.72 ms.<h4>4. Results and discussion</h4><h5>4.1. Utilization of ASAP-MS</h5>In the ASAP-MS spectra of the studied lacquers, signals of a several compounds were observed (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#fig0002">Fig. 2</a>). Signals of radical cations as well as protonated molecules of identified analytes were easily visible. Usually a slightly higher abundance of cation radicals compared to protonated molecules was observed (spectra of all samples are listed in Supplementary material B). The processes observed in the ASAP-MS spectra involve the release of alkyl phenol/alkyl catechol monomer(s) and cleavages of alkyl chain(s) after the carbon linked to the phenol/catechol ring (i.e. cleavage after the first, second and third alkyl carbons) and elimination of water either from polymer or released monomers (the pyrolytic/collision-induced fragmentation processes are discussed below in detail). The analysis of provided samples revealed the most important markers of specific types of lacquers.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Journal_of_Cultural_Heritage_77_2026_187_196_Fig_2_Spectra_of_lacquers_prepared_from_Toxicodendron_vernicifluum_Toxicodendron_succedaneum_and_Gluta_usitata_samples_U_V_and_B_0200c24c06.jpg" alt="Journal of Cultural Heritage, 77, 2026, 187-196: Fig. 2. Spectra of lacquers prepared from Toxicodendron vernicifluum, Toxicodendron succedaneum and Gluta usitata (samples U, V and B)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Journal_of_Cultural_Heritage_77_2026_187_196_Fig_2_Spectra_of_lacquers_prepared_from_Toxicodendron_vernicifluum_Toxicodendron_succedaneum_and_Gluta_usitata_samples_U_V_and_B_0200c24c06.jpg 245w," sizes="100vw" width="2750" height="1269"><h5>4.1.4. Study of MS/MS spectra of characteristic markers</h5>For all the standard materials, the most important markers were subjected to fragmentation after the collision induced dissociation (CID) in the Trap collision cell of the mass spectrometer (MS/MS experiments; all fragmentation spectra and observed diagnostic fragments including differences from theoretical masses are given in Supplementary material B).Signals of fragments with an intensity higher than the specified percentage of well known fragments arising from studied compounds were investigated and identified. Diagnostic fragments are given in Table B.2, Supplementary material B. The threshold signal was set for different compounds. For heptadecyl- and pentadecylcatechols, the threshold signal was defined as 5 % of the signal of dihydroxytropylium that is always an integral component of their collision spectra. For heptadecenyl- and pentadecenylcatechols the threshold signal was 2.5 % of dihydroxytropylium. For pentadecatrienyl catechol it was 100 % of dihydroxytropylium while for dodecylphenylcatechol it was 1 % of dihydroxytropylium. In case of 1-(3-hydroxyphenyl)-12-phenyldodecan-2-one, the threshold signal was defined as 17 % of the signal of hydroxyphenylethan-2-one. Finally, for 10-decylphenylphenol and 12-dodecylphenylphenol, 50 % of the signal of methylphenol was used as the threshold signal. These fragments were used for confirmation of the presence of lacquer compounds in routine measurements (at least one MS/MS spectrum was measured in each sample). The threshold signals were suggested and set in order to reach a sufficient yield of diagnostic fragments for unambiguous identification of individual markers. These signals are intended to be used in long term measurement in practice.<div>Fragmentation of heptadecylcatechols with 0-3 double bonds (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#fig0003">Fig. 3</a>a-d) is similar to that of pentadecylcatechols with same number of double bonds. In all cases, the signals of the characteristic fragments are well separated from the signals of the matrix.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Journal_of_Cultural_Heritage_77_2026_187_196_Fig_3_Fragmentation_spectra_of_heptadecylcatechols_possessing_0_3_double_bonds_6149330bc3.jpg" alt="Journal of Cultural Heritage, 77, 2026, 187-196: Fig. 3. Fragmentation spectra of heptadecylcatechols possessing 0-3 double bonds, (MS/MS; m/z of parent ions are: a) 342.2559, b) 344.2715, c) 346.2872, d) 348.3028)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Journal_of_Cultural_Heritage_77_2026_187_196_Fig_3_Fragmentation_spectra_of_heptadecylcatechols_possessing_0_3_double_bonds_6149330bc3.jpg 232w," sizes="100vw" width="3000" height="2017"><h5>4.2. Principal component analysis</h5>Excellent separation of particular types of Asian lacquers in Score Plot (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#fig0005">Fig. 5</a>a-d) was obtained by Principal Component Analysis based on the benzenediol and phenol derivatives described above. The Score Plot contains a set of 20 samples obtained from the Náprstek Museum Prague as well as other samples (BBI, BBO, SBI, SBO, U, V and B) in which lacquer compounds were detected (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#tbl0002">Table 2</a>). Note that in three other samples from The Náprstek Museum Prague, the lacquer compounds were not found at all.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Journal_of_Cultural_Heritage_77_2026_187_196_Fig_5_Score_plot_and_bi_plot_from_PCA_analysis_of_lacquers_taken_from_historic_objects_df82e0592a.jpg" alt="Journal of Cultural Heritage, 77, 2026, 187-196: Fig. 5. Score plot and bi-plot from PCA analysis of lacquers taken from historic objects, a. whole Score PCA plot, b. zoom of the T. succedaneum area, c. zoom of the T. vernicifluum area, d. zoom of the G. usitata area, e. whole PCA bi-plot, f. zoom of the T. succedaneum area in the PCA bi-plot, g. zoom of the T. vernicifluum area in the PCA bi-plot, h. zoom of the G. usitata area in the PCA bi-plot." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Journal_of_Cultural_Heritage_77_2026_187_196_Fig_5_Score_plot_and_bi_plot_from_PCA_analysis_of_lacquers_taken_from_historic_objects_df82e0592a.jpg 156w," sizes="100vw" width="3000" height="2994">The significance of suggested markers for the studied lacquers across the whole data matrix was confirmed. The effect of particular markers is reflected in related bi-plots (<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#fig0005">Fig. 5</a>e-h). Qualitatively, the results are in accordance with the former study obtained by py-GC/MS [<a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1296207425002572#bib0001">1</a>]. Since both cation-radicals and protonated molecules are formed in ASAP source with significant yield of both ion forms, their sum is an input into the data matrix for each substance (e.g., for pentadecenyl catechol, where the input is the sum of intensities I(m/z = 318)+ I(m/z = 319)), see PCA matrix in Supplementary material C. Measured m/z values of the analyzed compounds are in good agreement with the theoretical values calculated for specific elemental compositions (noted differences from the theoretical mass, dtm is in all cases less than or equal to 10 mDa).<h4>5. Conclusion</h4>The combination of atmospheric solids analysis probe with high resolution tandem mass spectrometry proved to be a fast and effective tool for analysis of historical Asian lacquer objects, their resolution and classification. The developed method is based on profiling of phenol and benezenediols derivatives. The fragmentation of alkylphenols and alkylbenzene diols after collision activated dissociation in Trap and Transfer collision cells was described. Scission of alkyl chains and elimination of water represent the main fragmentation processes important for identification. Cyclic ion mobility separation appeared to be a useful tool for “cleaning” of signals of the lacquer ions from the matrix signals allowing their better identification from the fragmentation spectra. Moreover, ASAP-MS and MS/MS allowed detection of diterpenic resins, triterpenic resins and arsenic sulphide pigments present along with Asian lacquers. Principal Component Analysis provided complete separation of samples into three clusters of Asian lacquers in Score Plot. A simple classification approach based on direct comparison of newly suggested classification parameters (CPs) allows reliable differentiation of lacquer samples according to their provenance. The developed method is now implemented in routine controls of lacquered objects and could be applied to the analysis of resins and ambers obtained from archaeological findings.</div></div>

Characterization of Asian lacquers by atmospheric solids analysis probe high resolution tandem mass spectrometry coupled with cyclic ion mobility separation

This study introduces a portable fluorescence-based microfluidic assay for rapid detection of multiple drugs in urine, including methamphetamine, benzoylecgonine, THC-COOH, and benzodiazepines. The system combines a compact reader with a dual-channel chip containing drug-specific antibodies, enabling simultaneous analysis within 5 minutes.Validation with 141 authentic urine samples demonstrated high sensitivity, specificity, and minimal cross-reactivity for both single and multiple drug use. The assay offers a cost-effective and field-deployable alternative to conventional immunoassays, supporting on-site forensic and clinical drug screening.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027">On-Site Microfluidic Assay for the Detection of Multiple Drugs in Urine</a></h4>Sanghag Ko, Sora An, Hyunjun Bae, Joonseok Seo, Suncheun Kim, Jeongmin Lee, Yohan Jeong, Juhyung Kim, Sangki Lee, Hyung Chul Kim, Seok Chung*, and Heesun Chung*ACS Omega 2026, 11, 8, 13697–13705<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acsomega.5c11027">https://doi.org/10.1021/acsomega.5c11027</a><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.<div>Forensic, clinical, and workplace testing for drugs of abuse in urine typically involves immunoassays and mass spectrometry (MS)-based methods. <a href="javascript:void(0);">(1,2)</a> Immunoassays are commonly used for rapid initial screenings, while MS-based assays are reserved for confirmatory testing. <a href="javascript:void(0);">(3−5)</a>A variety of immunoassay platforms have been developed for efficient drug screening. The lateral flow assay (LFA), a commonly used presumptive test in point-of-care test kits, offers rapid results within 5–10 min. These portable and inexpensive kits require minimal training, making them suitable for workplaces, schools, and roadside screening. <a href="javascript:void(0);">(6−9)</a> However, they are limited by relatively low sensitivity and specificity, which may lead to false positives and negatives. Therefore, positive results must be confirmed by MS-based methods. <a href="javascript:void(0);">(1,2,4)</a> On the other hand, laboratory-based immunoassays are automated analytical systems employed in forensic and clinical laboratories and utilized in workplace drug testing programs to detect drugs in biological samples with high throughput and precision. These systems commonly employ platforms such as enzyme-linked immunosorbent assay (ELISA), enzyme-multiplied immunoassay technique (EMIT), cloned enzyme donor immunoassay (CEDIA), and chemiluminescent immunoassay (CLIA). Nevertheless, their high operational cost and dependence on complex instrumentation restrict its use in point-of-care settings. <a href="javascript:void(0);">(10−13)</a>Paper-based microfluidic assays are widely used in point-of-care diagnostics and drug testing because of their simplicity, portability and accessibility. <a href="javascript:void(0);">(14,15)</a> In forensic applications, these platforms have also been developed for the detection of drugs and their metabolites in urine, as well as for alcohol and drug identification. <a href="javascript:void(0);">(16,17)</a> Despite being both user- and manufacturer-friendly, paper-based systems still face limitations inherent to cellulose substrates, including pore size variability, nonspecific binding, and restricted fluid-control precision. <a href="javascript:void(0);">(14,18)</a>To overcome these challenges, we developed an optimized microfluidic assay featuring nanointerstice integration, enabling rapid testing. <a href="javascript:void(0);">(19−21)</a> Unlike previous systems, our design operates entirely without external forces, instead leveraging capillary pressure to drive flow and nanointerstices to accelerate fluid filling.The microfluidic assay in this study includes a portable reader whose size is smaller (dimensions 12.7 cm × 15.0 cm × 20.6 cm, weight 2 kg, <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acsomega.5c11027/suppl_file/ao5c11027_si_001.pdf">Figure S1</a>). Microfluidic chip in which four drug-specific antibodies are immobilized across two channels. The design is optimized to minimize errors and stabilize the flow for precise results.To apply this assay, four target drugs were selected based on both global prevalence and recent domestic forensic trends. Globally, drug misuse has risen by approximately 26% over the past decade, with the darknet transactions being largely dominated by cannabis (48%), amphetamine-type stimulants (16%), cocaine (12%), and benzodiazepines (6%). <a href="javascript:void(0);">(22)</a> Recent UNODC and EMCDDA reports similarly emphasize the ongoing increase in methamphetamine trafficking, record-high levels of global cocaine supply, the continued predominance of cannabis use, and the rising nonmedical use and diversion of benzodiazepines. <a href="javascript:void(0);">(23,24)</a> In Korea, forensic drug case analyses in 2024 revealed that methamphetamine and cannabis were the most frequently identified substances. Notably, cocaine cases increased by 291% compared to the previous year, while benzodiazepines-related cases also showed a significant 40% year-overyear increase. <a href="javascript:void(0);">(25)</a> Considering these trends, methamphetamine, cocaine, cannabis, and benzodiazepines were selected as the primary targets of this study. For the detection of these substances in urine, antibodies specific to the parent compounds were used for methamphetamine (MET) and benzodiazepines (BZOs), while detection of cocaine and cannabis was achieved through antibodies against their primary urinary metabolites, benzoylecgonine (BE) and 11-nor-9-carboxy-tetrahydrocannabinol (THC-COOH), respectively. <a href="javascript:void(0);">(26−28)</a>The performance of the developed microfluidic assay was validated using both drug-spiked and authentic urine specimens to ensure its reliability under both controlled and actual forensic testing environments. Drug-spiked specimens were prepared in the laboratory and utilized to optimize assay parameters such as reagent concentration, flow rate, and detection sensitivity. Following the evaluation with drug-spiked specimens, authentic drug-positive urine specimens, provided by the National Forensic Service in Korea (NFS) and Paraguay (Lab HORVATH), were used to assess the practical applicability and diagnostic accuracy of the assay under realistic forensic testing scenarios.Therefore, the aim of this study was to develop and validate a portable microfluidic assay optimized for the simultaneous detection of four major drugs of abuse in urine─methamphetamine, cocaine, cannabis, and benzodiazepines─under realistic forensic testing conditions. By integrating nanointerstice technology and drug-specific antibodies within a compact platform, the assay was designed to address the limitations of existing point-of-care and laboratory-based immunoassay methods. Through performance evaluations using both drug-spiked and urine samples, this study was conducted to demonstrate the practical applicability, reliability, and diagnostic accuracy of the microfluidic assay for use in rapid on-site drug screening.<h4>2. Materials and Methods</h4><h5>2.4. Standard Preparation and Sample Acquisition</h5>Gas chromatography–mass spectrometry (GC-MS) was used to confirm urine specimens requiring verification. Analyses were conducted using an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7890B">Agilent 7890B GC</a> coupled to an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=5977A">Agilent 5977A mass selective detector</a> (electron–ionization mode). Helium was used as the carrier gas at 1.0 mL/min, and samples (1 μL) were injected in splitless mode. Separation was achieved on an HP-5 ms capillary column (30 m × 0.25 mm × 0.25 μm) with an oven program of 80 °C (1 min), ramped at 10 °C/min to 280 °C and held for 5 min (total run time: 28 min). The inlet and transfer-line temperatures were 280 and 280 °C, respectively. Qualitative identification was performed using selected-ion monitoring (SIM) targeting characteristic ions for each analyte.<h4>3. Results</h4><h5>3.1. Microfluidic Chip and Portable Reader</h5>This study employs a microfluidic assay that incorporates a simple sample preparation method, in which the urine specimen is diluted with a sample buffer (Absology, cat.no. ASB3) at a 1:10 ratio to minimize urine matrix effects and control the viscosity of the flow in the channel. 50 μL of the mixture is introduced onto a microfluidic chip for analysis with a potable reader (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027#fig1">Figure 1</a>).<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_8_13697_13705_Figure_1_Microfluidic_assay_8a0cedb715.jpg" alt="ACS Omega 2026, 11, 8, 13697–13705: Figure 1. Microfluidic assay. (A) Pretreatment of the urine specimen. To prepare the measurement, the user mixes the urine specimen with specimen buffer at a 1:10 ratio in the mixture dropper and then loads 50 μL of the mixture into each channel. (B) Photographs of the microfluidic assay. It shows the main elements of the assay system, comprising the microfluidic chip, mixture dropper, disposable pipet, and the portable reader device." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_8_13697_13705_Figure_1_Microfluidic_assay_8a0cedb715.jpg 130w," sizes="100vw" width="825" height="993"><h5>3.5. Measurement of Urine Specimens in the Microfluidic Chip</h5>Following the standard validation, we analyzed 141 authentic urine specimens: N = 30 methamphetamine users, N = 38 cocaine users, N = 30 cannabis users, and N = 13 benzodiazepine users, while the nondrug user group included 30 drug-free urine specimens (<a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/suppl/10.1021/acsomega.5c11027/suppl_file/ao5c11027_si_002.xlsx">Supporting Information 2</a>).The results obtained from the microfluidic assay were compared with those from the COBAS c311 for MET, THC-COOH, BZOs, and a point-of-care test kit test for BE. <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027#fig6">Figure 6</a>A confirms no detection of MET, BE, THC-COOH, and BZOs in the nondrug user group. In <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027#fig6">Figure 6</a>B, COI values for MET exceeded 1 in all methamphetamine specimens, with THC-COOH in one specimen, and no BE and BZOs detected. The sensitivity of the microfluidic assay─defined as the percentage of true positives─and the specificity─defined as the rate of true negatives─ <a href="javascript:void(0);">(32)</a>were both 100% (30/30) for MET when compared to COBAS c311. <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027#fig6">Figure 6</a>C shows that COI values for BE exceeded 1 in all cocaine specimens, with THC-COOH and BZOs detected in 34 and 9 specimens, respectively. The microfluidic assay demonstrated 100% (38/38) sensitivity and 100% (30/30) specificity in the detection of BE when compared to the point-of-care test kit. In <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027#fig6">Figure 6</a>D, all cannabis specimens had COI values above 1 for THC-COOH, and one specimen showed a COI above 1 for MET; no BE and BZOs were found in these specimens. Sensitivity and specificity for THC-COOH were both 100% (30/30) as compared to COBAS c311. <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027#fig6">Figure 6</a>E indicates that COI values for BZOs exceeded 1 in 6 out of the 13 benzodiazepine specimens, demonstrating a lower sensitivity of 46% (6/13), though specificity remained at 100% (30/30) compared to COBAS c311. In addition to single-drug analysis, specimen-level evaluation revealed that the microfluidic assay was also capable of detecting multidrug users. As shown in <a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/doi/10.1021/acsomega.5c11027#fig6">Figure 6</a>F, among the total 141 specimens, 30 were drug-free, 75 were single-drug users, and 36 were multidrug users. This demonstrates the assay’s ability to distinguish complex drug use patterns in forensic samples.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ACS_Omega_2026_11_8_13697_13705_Figure_6_Drug_use_patterns_in_N_141_samples_and_their_cutoff_index_COI_results_eec5e03112.jpg" alt="ACS Omega 2026, 11, 8, 13697–13705: Figure 6. Drug use patterns in N = 141 samples and their cutoff index (COI) results. COI results of (A) N = 30 individuals who did not consume any of the four drugs. (B) N = 30 individuals who consumed at least methamphetamine, compared with GC-MS results. (C) N = 38 individuals who consumed at least cocaine, compared with a rapid test kit. (D) N = 30 individuals who consumed at least cannabis, compared with GC-MS. (E) N = 13 individuals who consumed at least benzodiazepines, compared with LC-MS. (F) Samples consisted of nondrug group (N = 30), abusers who consumed one type of drug (N = 75), and others who took more than two types of drugs (N = 36)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ACS_Omega_2026_11_8_13697_13705_Figure_6_Drug_use_patterns_in_N_141_samples_and_their_cutoff_index_COI_results_eec5e03112.jpg 99w," sizes="100vw" width="1582" height="2484"><h4>5. Conclusions</h4>Immunoassay face distinct limitations. LFAs often suffer from low sensitivity and subjective result interpretation, while laboratory-based immunoassay systems require high costs and offer poor portability. In response to these challenges, this study developed a portable microfluidic assay for on-site screening. The assay enables semiquantitative detection of four drugs─methamphetamine, cocaine, cannabis, and benzodiazepines─using a microfluidic chip integrated with drug-specific antibodies. It provides clear positive/negative results, minimizing subjective interpretation, and also supports semiquantitative numerical outputs through COI values. Based on analysis of 141 authentic urine specimens tested, including 36 cases of polydrug use, the microfluidic assay demonstrated accurate and reliable detection across all four major drug classes, enabling robust performance even in polydrug use cases. The total analysis time remains under 5 min, ensuring practical usability for on-site testing. Its multiplexing capability allows for the simultaneous detection of multiple drugs in a single run, improving efficiency and utility in field testing scenarios such as roadside and workplace drug monitoring.Given those technological advantages and demonstrated performance, this assay represents a promising tool for broader field applications. Future research may focus on expanding the assay’s applicability to a wider range of detectable drug panel, improving its analytical throughput, or integrating wireless connectivity features for real-time monitoring and cloud-based data sharing.</div>

On-Site Microfluidic Assay for the Detection of Multiple Drugs in Urine

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The basics of IR microscopy will be discussed with an emphasis on current technologies. &nbsp;Improvements in measurements taken from modern insntrumentation will be described, showing the benefits of automation.&nbsp;<blockquote>Presenter: Louis Tisinger, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)Louis (Lou) Tisinger has a Ph.D. in Analytical Chemistry from Miami University in Oxford Ohio, where his graduate research involved the study of ATR imaging and microscope performance in vibrational spectroscopy. Most of his career has been related to pre- and post-sales support of FTIR spectrometers, microscopes, imaging systems, and thermal analytical instruments, focusing on analyzing customer samples, demonstrations, post-sales training, troubleshooting, and R&amp;D.</blockquote>

Agilent Technologies: Let's Talk About IR Microscopy

Let's Talk About IR Microscopy

The basics of IR microscopy will be discussed with an emphasis on the newest technologies.

In Part 1 of this workshop, we discuss the capabilities of the Praying Mantis accessory from Specac/Harrick in combination with the Cary 5000 UV-VIS/NIR System. &nbsp;It is a critical accessory for assessing the diffuse reflectance of small volumes of powders. &nbsp;Additional sampling capabilities through specialized reaction chambers allow for the control of sample pressure, temperature, and environment for catalyst studies.<blockquote>Presenter: Scott Melis, PhD (Application Scientist, Agilent Technologies, Inc.)Scott Melis has a PHD in Physics from Georgetown University in Washington, DC and started with Agilent in 2021 as a Molecular Spectroscopy Application Scientist. In his graduate work, Scott studied nanoparticle formation and growth for a variety of applications. Projects that he worked with include developing processes to deposit and characterize semiconducting molecular nano-cocrystals for use in optoelectronic devices as well as controlling polymer nanoparticle size through rapid mixing conditions.</blockquote>

Agilent Technologies: Optimize your FTIR, UV-Vis-NIR, Raman, Imaging, and Fluorescence Workflows

Part 1: Characterizing catalysts using an UV-VIS/NIR system with the Praying Mantis diffuse reflectance accessory.

Part 1 discusses the capabilities of the Praying Mantis accessory (Specac/Harrick) in combination with Cary 5000 UV-VIS/NIR System.

Catalyst Analysis with UV-VIS/NIR & Praying Mantis DR

Food scientists face growing challenges in characterizing complex food matrices with conventional analytical methods, which often fall short in sensitivity, robustness, and dynamic range. In this webinar, Dr Natasha Spadafora demonstrates a flexible platform that overcomes these limitations using a cryogen-free focusing trap. She will share two case studies: using high-capacity sorptive extraction with automated re-collection to reveal honey authenticity markers across a wide dynamic range; and enhancing SPME analysis with enrichment to uncover the nutritional potential of Mediterranean macroalgae. These examples will showcase how a flexible sampling toolkit (via the Centri platform) and advanced chemometric analysis (via ChromCompare+ analytical software) can provide highly informative data, as well as higher throughput and more insight into results.<h5>By attending this presentation, you will:</h5><ul><li>Centri’s flexible sampling tools (multi-step enrichment, high-capacity sorptive extraction, automated re-collection) help discover more from food matrices.</li><li>Centri’s automated workflows reduce hands-on time, increase throughput, and improve reproducibility.</li><li>Intelligent data analysis tools can automatically identify key features that differentiate complex samples.&nbsp;</li><li>These features are applied in practice with case studies on honey fraud detection and algae nutrient profiling.</li></ul><blockquote>Presenter: Natasha D. Spadafora &nbsp;(Assistant Professor, University of Ferrara, Italy)Natasha D. Spadafora focuses her research on food science at the University of Ferrara. Her main interest is to develop end-to-end solutions in food quality, flavour, and fragrance (FFF) at a multidisciplinary level, including metabolomics, transcriptomics, and sensorial perception. &nbsp;Her research across academia and industry leverages advanced analytical techniques like GC (GCxGC)-MS and chemometrics to address real-world challenges in food authenticity and waste reduction. She specializes in translating complex data into actionable insights for the food supply chain.Presenter:&nbsp;Rebecca Cole (Application Specialist, Markes International, Wales)Rebecca Cole received a BSc in genetics from the University of Cardiff, UK, and subsequently did a PhD at the University of Bristol, where she wrote her thesis on the population genetics of parasitic nematodes. She is now an application specialist at Markes, providing technical and application support to users around the world and developing applications using extraction and enrichment techniques for GC–MS.</blockquote>

Separation Science: Expanding the Sample Extraction Toolkit for Food Analysis by GC-MS

Expanding the Sample Extraction Toolkit for Food Analysis by GC-MS

Discover a versatile platform for overcoming challenges in food analysis beyond conventional limits. 

Extraction Toolkit for Food Analysis by GC-MS

<h4>Key Learning Points</h4><ul><li>Understand the purpose for common preventative measures towards GC challenges&nbsp;</li><li>Identify and attribute challenges to specific areas of the GC instrument or column&nbsp;</li><li>Recognize symptoms of challenges with method performance&nbsp;</li><li>Attribute common maintenance practices to specific remedies</li></ul><h4>Who Should Attend</h4><ul><li>Those who perform routine analysis using gas chromatography and would like to begin exploring techniques for troubleshooting&nbsp;</li></ul><blockquote>Speaker: Zachary Woodward (Senior Technical Specialist, Phenomenex)Zachary Woodward is a Senior Technical Specialist with Phenomenex, Inc, assisting laboratories with method development in the bio-pharma, environmental, and food industries. Zachary spent his formative years developing HPLC and GC methods with a pharmaceutical lab in Albany, NY, after which he developed HPLC and SPE methods in a clinical setting here in Southern California. Zachary received his B.Sci. in Chemistry from the College of William and Mary, was awarded his Master’s in Chemistry at San Diego State University, and is happy to speak with you today!</blockquote>

Phenomenex: GC Troubleshooting Quick Guide: Quick Fixes for Common Problems

GC Troubleshooting Quick Guide: Quick Fixes for Common Problems

Learn to troubleshoot common GC issues, recognize performance symptoms, and apply quick fixes in this practical webinar with expert Zachary Woodward.

GC Troubleshooting Quick Fixes for Common Problems

Selecting the right ionisation technique is a foundational step in any MS workflow. With no universal method, analysts must consider analyte properties and application goals to make informed choices. A misstep here can lead to poor sensitivity, incorrect identification, and inconsistent data.In this session, you’ll receive a comparative overview of key ionisation methods—including Electron Ionisation (EI), Electrospray Ionisation (ESI), Atmospheric Pressure Chemical Ionisation (APCI), and Chemical Ionisation (CI). Discover the strengths and limitations of each approach, explore real-world case examples, and gain practical knowledge on aligning ionisation strategies with specific analytical challenges.Plus, with an extensive Q&amp;A session, you'll have the opportunity to ask questions and gain deeper insights from our expert.<h5>By attending this session, you will:</h5><ul><li>Compare EI, ESI, APCI, and CI techniques to understand when and why to use each one.</li><li>Learn how analyte characteristics like polarity, volatility, and thermal stability influence method choice.</li><li>Explore real-world applications that highlight the impact of ionisation strategy on data quality and interpretation.</li><li>Have the opportunity to ask our expert about your unique challenges</li></ul><blockquote>Presenter: Emeritus Professor John Langley&nbsp;Emeritus Professor John Langley is a leading authority in Mass Spectrometry and Chromatography. His pioneering research delves into complex systems, harnessing cutting-edge techniques to push the boundaries of scientific discovery.John has held prestigious leadership positions, including Past President of the International Mass Spectrometry Foundation and Chair of the Separation Science Group of the Royal Society of Chemistry, shaping the field through innovation and collaboration. As an Editor for Rapid Communications in Mass Spectrometry, he continues to influence the advances in analytical chemistry.John has over 140 peer-reviewed publications, an H-index of 35, and contributions to more than 30 leading scientific journals, underscoring the interdisciplinary impact of his work. His ability to integrate separation science and mass spectrometry has earned him a unique distinction—he is the only person to have chaired both the British Mass Spectrometry Society and the Royal Society of Chemistry Separation Science Group.John's mastery of hyphenated approaches is widely recognised, earning him both the Chromatographic Society Jubilee Medal (2024) and the British Mass Spectrometry Society Medal (2021), another unique dual achievement in the field. His research spans chemistry, chemical biology, and oilfield chemistry, tackling intricate challenges and pioneering new analytical frontiers through techniques such as GC-MS, GC×GC-MS, HPLC-MS, LC×LC-IMS-MS, MS/MS, SFC-MS, and SFC-FID.</blockquote>

Separation Science: Choosing the Correct Ionisation Technique for Successful Mass Spectrometry Experiments

Choosing the Correct Ionisation Technique for Successful Mass Spectrometry Experiments

Join presentation and Q&A to learn how to select most suitable ionisation technique for your analyte and application

Choosing Ionisation Technique for Successful MS Experiments

This webinar will explore how the new Agilent 8850 gas chromatograph, now compatible with single and triple quadrupole mass spectrometry, can save users bench space, utility costs, and analysis time without compromising on performance. Viewers will see these features demonstrated through the applications of solvent purity by ASTM D7504 and gasoline aromatic composition by ASTM D5769.&nbsp;The 8850 GC using FID successfully accelerated the D7504 application from a runtime of 39 minutes using helium carrier gas down to 6 minutes using hydrogen. Combining the 8850 GC with the Agilent 5977C single quadrupole mass spec also yielded an accelerated solution for D5769 using hydrogen carrier gas with a total runtime of 9 minutes while achieving exceptional linearity for bulk compounds without compromising on sensitivity for trace analytes.<h5>By attending this presentation, you will learn about:</h5><ul><li>How the 8850 GC can help expand available bench space while using less electricity and gas for FID, TCD, and now both single and triple quadrupole MS applications</li><li>How the GC Intelligence features of the 8850 can help increase system up-time through advanced system monitoring, onboard maintenance, and guided troubleshooting</li><li>How the 8850 GC can accelerate applications with examples for solvent purity by ASTM D7504 and gasoline aromatic composition by ASTM D5769.</li></ul><h5>Who should attend:</h5><ul><li>Lab analysts using GC and GC/MS who are interested in increasing efficiency and throughput</li><li>Analytical lab managers looking to save time, operational expenses, and bench space</li><li>Petrochemical scientists producing high-purity aromatic streams and finished motor gasoline</li><li>Analytical chemists interested in the latest innovations in GC and GC/MS</li></ul><blockquote>Presenter: Scott Hoy (Applications Chemist, Agilent, Gas Phase Separations Division)Scott received his BS in Chemistry from the Georgia Institute of Technology in 2009 and his PhD in Analytical Chemistry from the University of South Carolina in 2013. He spent eight years working for ExxonMobil as a GC chemist in a refinery quality control lab and as a GC and GCxGC research chemist in R&amp;D. Scott joined Agilent Technologies in 2021 and is an applications chemist in the GC and GC/MS business unit in Wilmington, Delaware. His current work is focused on GC applications supporting conventional and renewable fuels, and the emerging GCxGC applications landscape.Presenter:&nbsp;James Cain (Product Manager, Agilent, Gas Phase Separations Division)James earned his BS in Chemistry from the University of Pittsburgh and his PhD in Organic Chemistry from the University of Arizona. After serving in various research and commercial roles with other organizations, including as an Agilent customer, he has been a product manager in the GC and GC/MS business unit with Agilent for five years. He is focused on understanding the needs of GC users globally, tracking changes in the market and regulatory landscape, and seeking new opportunities to apply Agilent innovation to emerging applications.</blockquote>

Separation Science: At Home on Any Bench: High-Performance GC/MS for Every Lab

At Home on Any Bench: High-Performance GC/MS for Every Lab

Save space and time while increasing efficiency and throughput with the Agilent 8850 gas chromatograph.

Are you ready to meet the growing demands for data integrity and operational efficiency in your laboratory? Laboratories today are under pressure to manage data more effectively while ensuring seamless integration of testing processes and results. In this latest session on Digital Classrooms, we will introduce Shimadzu’s New LabSolutions CS, powered by i-QLinks for the next level compliance.This next-level solution integrates everything from test preparation and execution to results management and quality control, all within a centralized platform. Learn how its innovative, web-based interface enables you to: 1. Automate test planning, analysis, and reporting for streamlined workflows. 2. Capture data effortlessly without human intervention, reducing errors. 3. Centralize test management to ensure smooth and efficient operations. 4. Monitor progress and analyze results anytime, anywhere, for control over your laboratory processes.Don’t miss this opportunity to see New LabSolutions CS in action. Register Now!<h5>Learning Objectives</h5><ul><li>Discover how LabSolutions CS enables seamless integrated test management.</li><li>Learn strategies to enhance efficiency in analytical lab operations.</li><li>Explore centralized monitoring for streamlined analysis insights.</li><li>Understand how web-based reporting and approval can transform workflow efficiency.</li></ul><blockquote>Presenter: Sateesh Tummala (Deputy General Manager, Shimadzu (Asia Pacific) Pte Ltd)Sateesh has 17+ years of working experience with Shimadzu in various roles from technical, regional business development. His is now focusing on global business activities for Informatics products. He has wide experience in Pharma domain, is well versed with regulatory compliance guidelines and is implementing Laboratory Digital and IT Systems. He is passionate to collaborate with customers to deliver the best experience of Shimadzu Systems, be part of their laboratory transformation journey towards digitalisation and automation of lab software.Presenter:&nbsp;Kanimozhi Sivarajan (Informatics Manager, Shimadzu (Asia Pacific) Pte Ltd)Dr. Kani is having 10 years of experince in Laboratory Management and Information Systems. She is Serving as Informatics Manager at Shimadzu Asia Pacific, Singapore, &nbsp;providing Lab Informatics Solutions such as LabSolutions CS, LIMS and other QMS applications. She is supporting customers from various segments on implementing laboratory automation and responsible for providing consultation on streamlining Lab Workflows, Regulatory Compliance requirements for Electronic Data Management and Lab Practices/Analysis.</blockquote>

Shimadzu: Unifying Data, Automating Analysis: Introducing The New LabSolutions CS

Unifying Data, Automating Analysis: Introducing The New LabSolutions CS

Boost lab efficiency and data integrity with Shimadzu’s LabSolutions CS. Discover seamless test integration, automation, and centralized monitoring.

Introducing The New LabSolutions CS

As cosmetic formulations grow more complex and regulations tighten, ensuring product safety, compliance, and sustainability requires advanced analytical solutions. This webinar brings together expert-led sessions and real-world insights that cover three key challenges: raw material testing, nanoparticle characterization, and fragrance allergen analysis.<ul><li>New Standard XP CEN ISO/TS 19590:2024 – Characterization of Nano-Objects Using Single Particle ICP-MS. Application to Cosmetics: Explore the ISO/TS 19590:2024 standard, and hear from guest speaker Mathieu Menta (UT2A) who will present its applications in cosmetics, highlighting both technical and regulatory perspectives.</li><li>Raw Material Testing Through Bags &amp; Closed Containers with the Vaya Handheld Raman System: Discover how innovative spatially offset Raman spectroscopy (SORS) technology &nbsp;allows non-destructive identification &nbsp;through transparent and opaque packaging—eliminating sampling waste, improving productivity, and supporting ISO 22716 GMP compliance and sustainable practices.</li><li>Analysis of Fragrance Allergens: Following European Regulation 2023/1545: Learn how Agilent’s GC/TQ workflow helps cosmetics manufacturers comply with new allergen regulations by reliably identifying and quantifying fragrance allergens—even in complex formulations—while minimizing false results.</li></ul><h5>Key learning objectives:</h5><ul><li>Learn how to verify raw materials directly through packaging using Raman spectroscopy to eliminate sampling and reduce waste</li><li>Apply ISO/TS 19590:2024 for accurate characterization of nanoparticles in cosmetic formulations using single-particle ICP-MS</li><li>Gain practical insights from a customer case on implementing spICP-MS for nano-object analysis under real regulatory and quality constraints</li><li>Quantify fragrance allergens in complex cosmetic matrices with high selectivity and sensitivity using GC/TQ</li><li>Enhance analytical workflows by minimizing sample handling, reducing false identifications, and improving compliance with current regulations</li></ul><h5>Who should attend?</h5><ul><li>QC/QA professionals in cosmetics and pharmaceuticals</li><li>Regulatory and compliance managers</li><li>Analytical scientists, chemists and lab managers</li><li>R&amp;D teams</li><li>Anyone involved in nanoparticle characterization, raw material verification, or cosmetic testing</li></ul><blockquote>Presenter: Hansel Koelblen (Application Engineer - GC &amp; GC/MS, Agilent Technologies)Hansel has worked with GCMS instrument for almost 10 years. He joined Agilent in 2017, first as a Field Service Engineer and now holds the position of France GC &amp; GC/MS Application Engineer.Presenter: Thibault Brule (Product Specialist – Molecular Spectroscopy, Agilent Technologies)Thibault Brule is Molecular Spectroscopy Product Specialist. He joined Agilent Technologies on November 2024. His main role is to provide applicative and technical support to the network on UV-Vis-NIR, FTIR and Raman spectroscopies.Presenter: Yolande Abdelnour (Product Specialist - Atomic Spectroscopy, Agilent Technologies)Yolande Abdelnour holds a Ph.D. in Chemical and Plasma Process Engineering from “Ecole Supérieure de Chimie” in Paris and “University of Paris Sorbonne”. She worked as a research engineer at “Photowatts” for 3 years and then joined Varian in 1997 as European ICP-MS product specialist. Since 2010, she occupies within Agilent Technologies the position of Product Specialist for the Atomic Spectroscopy techniques including Atomic Absorption, Microwave Plasma, Inductively Coupled Plasma coupled to Optical Emission Spectroscopy, Single Quad and Triple Quad Mass Spectrometry.Presenter: Mathieu Menta (Application Engineer, Ultra- Trace Analyses Aquitaine (UT2A) - Pau)Mathieu Menta is Applications Engineer at UT2A since 2011. He is responsible for the physico-chemical characterization of nanomaterials and the speciation of trace elements by elemental mass spectrometry. He is also involved in project management and quality assurance. He has co-authored several scientific publications, notably on the quantification of nanoparticles in food, cometics ans pharmaceutics using spICP-MS and on the rapid and accurate determination of elemental impurities in pharmaceutical products using a combination of standard addition and isotope dilution methods</blockquote>

Agilent Technologies: Characterization in Cosmetics: Nano-Objects ISO 19590:2024, Raw Material & Fragrance Allergens

Characterization in Cosmetics: Nano-Objects ISO 19590:2024, Raw Material & Fragrance Allergens

Ensure safety and compliance in cosmetics with insights on raw materials, nanoparticles, and allergens. Discover cutting-edge tools like ICP-MS and Raman SORS.

Nano-Objects, Raw Material, Fragrance Allergens in Cosmetics

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div>Are you setting up new GC-MS methods? Don’t know when to perform the required maintenance on your GC-MS system? Do you struggle to reoptimize methods after maintenance? Are you spending too long on data review? If you answer is yes to any of these questions you cannot miss this webinar! Our specialists will address all these areas and offer helpful software hints and tips to streamline your workflow.Key topics include:<ul><li>Overview of Thermo Scientific Chromeleon software</li><li>Importing pre-optimized workflows to cut method development time</li><li>Automating sample preparation with autosampler methods</li><li>Using intelligent software for peak system performance and proactive maintenance</li><li>Automating data review to speed up processing</li></ul>Ideal for laboratories performing food safety, environmental monitoring, and battery analysis. Register now for this educational webinar.Cannot attend the broadcast on June 17? Please register to automatically receive the link to the webinar recording.<blockquote>Presenter: Nicholas Warner (Product Applications Specialist GC-MS, Thermo Fisher Scientific)Nicholas is a product specialist with a strong scientific background in GC and GC-MS applications. Originally from Canada, he has worked as an environmental researcher for 14 years within Norway before moving to join the Thermo Fisher Scientific team in Bremen, Germany in 2021. With a background in Environmental/Analytical chemistry, he is a specialist in the analysis of emerging harmful substances in the environment using gas chromatography mass spectrometry and high-resolution mass spectrometry.Presenter: Zoe Julian (Product Marketing Manager, Thermo Fisher Scientific)Zoe Julian is a product marketing manager for chromatography and mass spectrometry software at Thermo Fisher Scientific.With over 12 years' experience of working with chromatography and mass spectrometry techniques with a background in GC and GC-MS(/MS) organic environmental analysis, she has helped many laboratories and industries improve their workflows through a unique understanding of their challenges. Transitioning to a focus on Chromeleon CDS she has shown customers how software solutions can improve their productivity and support their day-to-day operations.Presenter: Adam Ladak (Global Product Marketing Manager, GC Quadrupole MS, Thermo Fisher Scientific)Adam started his career working in a contracting testing lab analyzing sports supplements and horse feed for prohibited substances. He has over 20 years of experience in the analytical testing industry and has worked for leading instrument manufacturers in various roles from an application specialist to a global marketing role focused on food and environmental testing. Adam is passionate about utilizing our GCMS instrumentation to meet the customer needs and solve real world problems.</blockquote></div></div></div>

Thermo Fisher Scientific: Software masterclass: Hints and tips to help optimize your GC-MS

Software masterclass: Hints and tips to help optimize your GC-MS

Optimize GC-MS methods faster! Learn maintenance tips, automated workflows, and data review shortcuts with Thermo Scientific Chromeleon software.

Software Hints and tips to optimize your GC-MS

LC-MS and GC-MS datasets can be challenging to process and extract meaningful information from. However, when correctly executed, these techniques can be unmatched for detecting unknown components or monitoring known ones.Learn how Wiley's NEW KnowItAll LC Expert and MS Expert can help reduce barriers to LC-MS and GC-MS processing and data analysis by automating identification of unknown compounds. By combining fast, flexible deconvolution into a single workflow with database search of Wiley’s comprehensive, trusted spectral libraries, KnowItAll can improve your workflow and save hours of manual analysis time.Join us to see these exciting new technologies through a series of real-world examples.<blockquote>Presenter: Zille Huma (Senior Editor, Software Products, Wiley Science Solutions)Zille Huma is a senior editor for Wiley Science Solutions where she supports new and existing database releases. Huma previously completed her bachelor's degree in chemistry at Rutgers University and has been with Wiley since 2018.Presenter: Nadia Laschuk (Product Manager, New Techniques, Wiley Science Solutions)Dr. Nadia Laschuk is a Product Manager for Wiley Science Solutions, where she oversees the development of new products and databases, while supporting existing KnowItAll capabilities. She earned her Ph.D. in Materials Science from Ontario Tech University, where she executed chemistry research using a variety of instrumental analytical techniques. Since joining Wiley in 2022, Nadia has focused on cheminformatics and software development.Presenter: Michelle D’Souza, PhD (Product Manager, Software Products, Wiley Science Solutions)Dr. D’Souza brings years of insight and knowledge in the area of spectral informatics with leadership roles at both Wiley and Bio-Rad Laboratories. In addition to her multiple years as a scientific researcher at Abbott (now AbbVie) and DuPont, she has a Ph.D. in Chemistry from Northern Illinois University and a Masters in Analytical Chemistry from the Chinese Academy of Preventative Medicine. She earned a BS degree from Chemistry Department of Beijing University. &nbsp;</blockquote>

Wiley: Automate Non-Targeted LC MS/MS and GC-MS Component Identification

Automate Non-Targeted LC MS/MS and GC-MS Component Identification

Learn how KnowItAll LC Expert and MS Expert automate LC-MS and GC-MS data analysis, enabling faster deconvolution and identification of unknown compounds.

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