<p><strong>Sample preparation is one of the most time-consuming steps in analytical workflows. Whether a lab is conducting forensic analyses, environmental testing, pharmaceutical development, or food safety analysis, researchers often face the challenge of concentrating samples before analysis. </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5392"><strong>Nitrogen blowdown evaporation</strong></a><strong> has become a widely used technique for this purpose because it is simple, efficient, and adaptable to a wide range of solvents. When preparing samples for evaporation, factors that play a major role in efficiency include: needle gauge and flow rate. Optimization of these parameters could aid in developing more effective solvent evaporation methods.</strong></p><p>At Organomation, all <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=362&amp;manufacturerItems=540&amp;page=2"><strong>blowdown evaporators</strong></a><strong> </strong>come with standard 4-inch, 19-gauge stainless steel needles. This size has proven to be effective for most laboratory applications as it balances evaporation speed with nitrogen consumption while also accommodating for common sample tube sizes. For labs that need to process higher sample volumes, 16-gauge and 14-gauge needles are also available. All needles are constructed from <strong>304 stainless steel</strong> and feature a luer lock fitting for easy attachment and removal from the nitrogen evaporator.</p><p>Traditionally, Organomation has recommended using a <strong>straight 19-gauge needle with a flow rate of 0.33 L/min per sample</strong>. This setting works well for most solvents, but how could changing these parameters aid in increasing evaporation efficiency?</p><ul><li>Could switching to a larger gauge needle accelerate evaporation?</li><li>Does increasing nitrogen flow rate always improve efficiency, or are there trade-offs?</li><li>Can needle design modifications reduce splashing while maintaining faster drying times?</li></ul><p>To investigate this, a series of <strong>controlled trials using methanol </strong>as a representative solvent were conducted. The study compared evaporation rates across different <strong>needle gauges, flow rates, and needle shapes </strong>to provide practical insights for laboratories seeking to optimize their sample preparation methods.</p><h3><strong>Needle Variations</strong></h3><p>While straight stainless-steel needles are the standard for nitrogen blowdown evaporation, alternative needle shapes may influence how nitrogen interacts with the solvent surface. Two main modifications were tested in this study:</p><ul><li><strong>Bent needles:</strong> Designed with either a short bend or a long bend near the end of the needle. The goal was to change the angle of nitrogen delivery to reduce splashing and improve solvent exposure.</li><li><strong>Pseudo-spiral needles: </strong>Created by adding two bends to the bottom quarter of 19-gauge needles, forming it into a spiral-like curve. These were intended to generate a more turbulent nitrogen flow pattern, potentially enhancing evaporation.</li></ul><p>Both designs were hypothesized to improve evaporation efficiency by concentrating gas flow while minimizing sample loss.</p><h3><strong>Experimental Design</strong></h3><p>The study evaluated<strong> how needle gauge, needle modifications, and nitrogen flow rate influence methanol evaporation </strong>under controlled conditions. All experiments were conducted at both room temperature and 63 °C, the recommended bath temperature for methanol.</p><h4><strong>Needle Gauge</strong></h4><ul><li><strong>Compared 19-, 16- and 14-gauge needle </strong>evaporation rates.&nbsp;</li><li>Used each needle’s recommended flow rate<ul><li><strong>19 ga: </strong>0.33 L/min</li><li><strong>16 ga: </strong>0.83 L/min</li><li><strong>14 ga: </strong>1.2 L/min</li></ul></li><li><strong>Purpose:</strong> determine whether larger needle diameters accelerate evaporation relative to the standard 19-gauge configuration.</li></ul><h4><strong>Needle Modifications</strong></h4><ul><li>Compared straight needles to bent and pseudo-spiral designs.&nbsp;</li><li>19- and 16-gauge needles were modified to have a short bend or long bend on the end of the needle.&nbsp;</li><li>Additional pseudo-spiral designs of the 19-gauge needles were created by bending the lower quarter of the needle into two spiral shapes.&nbsp;</li><li><strong>Purpose: </strong>evaluate whether altering gas flow direction could improve evaporation rates.</li></ul><h4><strong>Flow Rate Variation</strong></h4><ul><li>Increased the nitrogen flow rate past original recommendations.</li><li>Used the recommended flow rate for 16-gauge needles on the 19-gauge bent needles.</li><li>Used the recommended flow rate for 14-gauge needles on the 16-gauge bent needles.</li><li><strong>Purpose </strong>assess whether higher flow rates improve efficiency and if pairing higher flow rates with bent needles can reduce splashing.</li></ul><h3><strong>Results</strong></h3><h4><strong>Table 1. Different Needle Sizes - Methanol Evaporation Rate</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_2_17a8479b99.jpg" alt="Organomation: The Effect of Needle Gauge and Flow Rate on Evaporation Rate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_2_17a8479b99.jpg 245w," sizes="100vw" width="1237" height="224"></p><p>The 14-gauge had the fastest evaporation rate, which was expected, as the standard flow rate for this size needle is the fastest. All needle sizes showed an increase in evaporation when using the heated water bath.</p><h4><strong>Table 2. 19-gauge Needle - Methanol Evaporation Rates</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_3_01c176196e.jpg" alt="Organomation: The Effect of Needle Gauge and Flow Rate on Evaporation Rate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_3_01c176196e.jpg 245w," sizes="100vw" width="1473" height="346"></p><h4><strong>Table 3. 16-gauge Needle - Methanol Evaporation Rates</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_4_ccd087323f.jpg" alt="Organomation: The Effect of Needle Gauge and Flow Rate on Evaporation Rate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_4_ccd087323f.jpg 245w," sizes="100vw" width="1473" height="222"></p><p>The most effective needle shape for both the 19- and 16-gauge needles, without increasing nitrogen flow rate, proved to be the standard straight needles for both room temperature and heated water bath evaporation. There was a significant jump observed in the heated evaporation, especially in the 16-gauge needles, with over 75% increase. When comparing the short and long bend needle configurations, there were no significant differences, as the style with faster evaporation varied between trials.</p><h4><strong>Table. 4 Methanol Evaporation Rates with Increased Flow Rates</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_5_4c4ba4d1d8.jpg" alt="Organomation: The Effect of Needle Gauge and Flow Rate on Evaporation Rate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_The_Effect_of_Needle_Gauge_and_Flow_Rate_on_Evaporation_Rate_5_4c4ba4d1d8.jpg 245w," sizes="100vw" width="1524" height="388"></p><p>At room temperature, bent needles showed only a slight improvement in evaporation rates compared to larger gauge straight needles at the same flow rates. However, under heated water bath conditions, needle gauge size played a more significant role. The larger-gauge straight needles achieved substantially higher evaporation rates than bent needles at comparable flow rates. This indicates that gauge size and flow rate have a stronger influence than needle shape when a heated water bath is used.</p><h3><strong>Key Takeaways</strong></h3><ul><li><strong>19-gauge needles remain reliable</strong>, especially at higher-than-standard flow rates.</li><li><strong>Flow rate is critical: </strong>higher flow rates generally increased evaporation speed, but also introduced challenges such as potential sample splashing</li><li><strong>Heated baths amplify overall performance: </strong>all needles performed significantly better at 63 °C water baths than at room temperature.</li><li><strong>Needle design benefits:</strong> bent needles showed potential in minimizing splashing. They allowed for increased flow rate and for the needle to be closer to the sample solution inside the tube.</li></ul><h3><strong>Applying These Findings in Your Lab</strong></h3><p>The results of this study show that needle gauge, flow rate, and needle design can all significantly influence evaporation speed. But how do these findings translate into day-to-day laboratory use?</p><ul><li><strong>Stick with the standard setup for most workflows</strong>. For routine sample preparation, the 19-gauge needle at 0.33 L/min remains an ideal choice, offering reliable performance while minimizing nitrogen consumption.</li><li>If your lab works with high-volume samples or needs quicker turnaround, switching to a 16-gauge needle and increasing the flow rate from 0.83 L/min to 1.2 L/min could provide significant time savings especially when paired with a heated water bath.</li><li>Faster nitrogen delivery can improve speed, but it also increases the risk of sample loss. Start by slowly increasing flow rate, and then adjust needle position above the solvent surface to control splashing.</li><li>Consider using bent or spiral needles for reducing splashing while maintaining strong evaporation rates. While not always necessary, they may be helpful in some scenarios.</li></ul><h3><strong>Conclusion</strong></h3><p>For most applications, the standard 19-gauge, 0.33 L/min setting remains sufficient. However, labs working with high-volume samples or those needing faster evaporation can benefit from using 16-gauge needles at higher flow rates, especially when paired with a heated water bath. Needle modifications can help address the issue of sample splashing, although they have shown to decrease the rate of evaporation when compared to the standard straight needles of the same gauge. Ultimately, the choice of needle gauge and flow rate should balance speed, safety, and solvent conservation. These results provide a framework for labs looking to optimize their evaporation setup.</p><blockquote><p><a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/contact"><strong>Contact our team</strong></a> to discuss the best needle option and gas parameters for your application.</p></blockquote>

The Effect of Needle Gauge and Flow Rate on Evaporation Rate

<p><strong>How can we make the production of supercapacitors for energy storage more sustainable and replace the traditionally used but toxic solvent NMP (N-methyl-2-pyrrolidone)? According to scientists from CATRIN at Palacký University, the “green” solvents Cyrene and Tamisolve may be a suitable alternative. In an article published in the </strong><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1385894725130696?via%3Dihub#s0060"><i><strong>Chemical Engineering Journal</strong></i></a><strong>, they have shown that these solvents can be used in production without reducing the performance of the equipment. They thus offer a path to the next generation of sustainable, high-performance supercapacitors for industrial use.</strong></p><p>“<i>Supercapacitors are one of the modern technologies for storing electric energy. As sustainable energy storage becomes more prominent, it is essential to replace the hazardous solvents used in the production of supercapacitor electrodes. Our study presents Cyrene and Tamisolve as environmentally friendly alternatives to the toxic solvent NMP, which is traditionally used in production. Both tested solvents enabled the preparation of electrodes that maintain high electrochemical performance while improving environmental compatibility</i>,” said <strong>Michal Otyepka</strong>, <strong>corresponding author</strong> of the article.</p><p>The electrodes were prepared using nitrogen-doped graphene as the active material in combination with two types of binders. The first was a common fluorinated binder (PVDF), which is widely used in industry, including in the manufacturing of battery electrodes. The researchers also tested a fluorine-free binder (PVP), which has a lower environmental impact and is more soluble in environmentally friendly solvents. Using various combinations, they monitored the performance and stability of the electrodes as well as their mechanical resistance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Vedci_z_CATRIN_nabizeji_zelenejsi_cestu_pro_vyrobu_superkondenzatoru_443775296a.jpg" alt="CATRIN: CATRIN researchers offer a “greener” way to make supercapacitors" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Vedci_z_CATRIN_nabizeji_zelenejsi_cestu_pro_vyrobu_superkondenzatoru_443775296a.jpg 245w," sizes="100vw" width="1536" height="768"></p><p>“<i>The results showed that not only can the alternative solvents Cyrene and Tamisolve fully replace the toxic solvent NMP, but also that the prepared electrodes have the necessary mechanical properties. Their compatibility with both fluorinated PVDF and non-fluorinated PVP binders, together with excellent layer uniformity and electrochemical stability, makes them ideal for use in scalable applications. This is essential for industrial production,</i>” said the publication’s <strong>first author, Ivan Dědek</strong>.</p><p>Cyrene, or dihydrolevoglucosenone, is obtained from renewable biomass sources such as cellulose. Tamisolve (N-butyl-2-pyrrolidone) is a substance related to the commonly used NMP, but is more gentle on human health and the environment.</p><p>Supercapacitor research has been a priority at CATRIN for almost ten years. In addition to developing new active materials, such as the successful nitrogen-doped graphene (SC-GN3), it also focuses on environmentally friendly and industrially feasible manufacturing processes. The replacement of toxic NMP with the “greener” solvents Cyrene and Tamisolve confirms that more sustainable production can go hand in hand with high performance and represents an important step towards industrial implementation.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S1385894725130696?via%3Dihub#s0060"><strong>Toward transitioning to green and sustainable supercapacitors</strong></a></h4><p>Ivan Dědek, Vojtěch Kupka, Veronika Šedajová, Petr Jakubec, Matěj Navrátil, Michal Otyepka&nbsp;</p><p>Chemical Engineering Journal, 529, 2026, 172220</p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.cej.2025.172220">https://doi.org/10.1016/j.cej.2025.172220</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><h4><strong>Abstract</strong></h4><p>The rapid advancement of supercapacitor technologies has intensified the demand for sustainable electrode fabrication methods that minimize environmental impact. A major challenge arises from the extensive use of the toxic solvent N-methyl-2-pyrrolidone (NMP), which is subject to increasingly stringent regulatory restrictions. We demonstrate that NMP can be effectively replaced with two green solvents, dihydrolevoglucosenone (Cyrene) and N-butyl-2-pyrrolidone (Tamisolve), without compromising electrochemical performance. Electrode formulations were prepared using nitrogen-doped graphene as the active material, in combination with either polyvinylidene fluoride (PVDF), a widely employed fluorinated binder, or polyvinylpyrrolidone (PVP), a non-fluorinated alternative with improved environmental profile. Optimized coatings exhibited high mass loadings exceeding 6 mg cm−2 while maintaining strong adhesion to current collectors, an often overlooked yet critical parameter for scalable manufacturing. Electrochemical testing revealed that PVDF in Cyrene delivered an energy density of 66.6 Wh kg−1 at a power density of 1.85 kW kg−1, with excellent cycling stability, retaining 91 % of capacitance after 100,000 cycles. PVP in Cyrene provided a more environmentally benign alternative, achieving an energy density of 64.2 Wh kg−1 at 1.80 kW kg−1, with 78 % capacitance retention after 100,000 cycles, thereby highlighting the trade-off between performance and sustainability.</p>

CATRIN researchers offer a “greener” way to make supercapacitors

<p><strong>🎤Dr. Kristen Vanderveen </strong>(Dr. Vanderveen's chemistry education content on YouTube: <strong>@</strong><a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@drvchemistry"><strong>drvchemistry</strong></a>)</p><p><strong>Dr. Kristen Vanderveen is a chemistry teacher at The Bromfield School with over 20 years of experience teaching high school chemistry, including AP Chemistry. Her background includes working as a protein chemist before transitioning to education.</strong></p><p>In this episode of Concentrating on Chromatography, David interviews his former high school chemistry teacher, Dr. Kristen Vanderveen from The Bromfield School, about teaching separation science at the high school level.</p><p>Dr. Vanderveen shares her approach to introducing chromatography, filtration, and gravimetric analysis to both first-year chemistry students and AP Chemistry students. She discusses the hands-on experiments that work best in a high school setting, including paper chromatography with food dyes, TLC separations, and the challenges of balancing lab time with curriculum requirements.</p><h4><strong>Topics discussed:</strong></h4><ul><li>Separation methods taught in high school chemistry (filtration, paper chromatography, TLC)</li><li>Gravimetric analysis and precipitation experiments for AP Chemistry</li><li>Student engagement strategies and memorable lab activities</li><li>Balancing theoretical concepts with hands-on experimentation</li><li>Common student misconceptions about separation techniques</li><li>Preparing students for college-level chemistry courses</li></ul><h3><strong>Video Transcription</strong></h3><h4><strong>How Separation Science Is Introduced in High School Chemistry</strong></h4><p>Separation science may seem like an advanced topic associated mainly with research laboratories and analytical instrumentation, but its foundations are introduced much earlier. In this interview, chemistry teacher <strong>Kristen</strong> reflects on how separation methods are taught at the high school level, especially in <strong>AP Chemistry</strong>, and how these early experiences help prepare students for future studies in chemistry and related fields.</p><h4><strong>Filtration and chromatography as core teaching tools</strong></h4><p>According to Kristen, one of the most important separation techniques taught in high school chemistry is <strong>filtration</strong>, particularly through <strong>gravimetric analysis</strong>. In AP Chemistry, students are expected to understand how to form, isolate, dry, and weigh a precipitate, making filtration one of the most frequently practiced laboratory skills. These exercises help students connect separation techniques with stoichiometry, quantitative analysis, and proper laboratory handling.</p><p>Another key topic is <strong>chromatography</strong>. Although AP Chemistry does not cover chromatography in great technical depth, students are introduced to important principles such as the <strong>stationary phase, mobile phase, solvent front, and Rf values</strong>. Kristen explains that these ideas are most effectively learned through hands-on experiments, which is why she regularly includes <strong>paper chromatography</strong> and, in some cases, <strong>thin-layer chromatography (TLC)</strong> in her classes.</p><h4><strong>Hands-on experiments make the concepts real</strong></h4><p>Among the most engaging classroom activities are chromatography labs based on <strong>food dyes and marker inks</strong>. Students may begin with a guided exercise to learn how to spot samples, prepare chromatography chambers, and compare separations under different solvent conditions. In more advanced versions of the experiment, they are asked to design their own solvent systems to optimize the separation of selected dyes and then present their findings in a small poster format.</p><p>Kristen notes that these activities help students understand not only the scientific principle but also the practical challenges of separations. They quickly learn that details matter — for example, how sample spotting affects band shape, or how easy it is to make errors by placing the paper incorrectly in the solvent. These moments often become valuable “aha” experiences, showing students that experimental science requires patience, repetition, and careful observation.</p><h4><strong>Balancing theory, time, and skill development</strong></h4><p>One of the biggest challenges in teaching separation science at the high school level is <strong>limited classroom time</strong>. Modern school schedules, AP curriculum demands, and the need to teach many other foundational laboratory skills mean that only a few separation methods can be explored in depth. While students are introduced to concepts such as <strong>distillation, evaporation, and decanting</strong>, chromatography and filtration are the main techniques they actively practice.</p><p>Kristen emphasizes that the goal is not to make students experts, but to ensure they leave high school with enough familiarity to succeed in college-level chemistry. If they have filtered a precipitate, seen chromatography in action, and understand that mixtures can be separated based on physical and chemical properties, then they are better prepared for more advanced topics such as <strong>separatory funnels, column chromatography, GC-MS, or LC-MS</strong> later in their education.</p><h4><strong>Building the bridge to future chemistry careers</strong></h4><p>The interview also highlights a broader point: high school chemistry is often the <strong>first point of contact</strong> students have with analytical thinking and laboratory separation methods. While they may not yet know about the full range of chromatographic and mass spectrometric techniques used in research and industry, these early lab experiences build the conceptual framework needed for future growth.</p><p>Kristen also points out that students are often unaware of the many careers connected to analytical chemistry beyond academia. From teaching and research to applications science, instrument support, and industrial laboratories, separation science opens doors to a wide range of scientific paths. High school exposure may be basic, but it plays an important role in making those future possibilities accessible.</p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote><blockquote><h4><strong>Concentrating on Chromatography Podcast</strong></h4><p>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!</p><p>You can find <strong>Concentrating on Chromatography Podcast </strong>in podcast apps:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL"><strong>Spotify</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185"><strong>Apple podcast</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography"><strong>podscan</strong></a></li></ul><p>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos"><strong>YouTube channel</strong></a></p></blockquote>

Teaching Separation Science in High School

Article

Product

Academy

Video

Scientists

Scientific article

Interview

Science and research

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

CATRIN

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

New Food magazine

Separation Science

Metrohm

Agilent Technologies

MDPI

GERSTEL

Thermo Fisher Scientific

C&EN

<p><strong>The Agilent TRS100 Raman system is ideal for fast assay of tablets, capsules, and other dosage forms. Transmission Raman technology from Agilent enables simple method-development and deployment in QC applications. It is easy to implement in analytical laboratories and production areas, and has regulatory approvals for content uniformity (CU), assay, and identification (ID) applications.</strong></p><blockquote><p><strong>Presenter:</strong> Yanqia Wang, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)</p><p>Dr. Yanqia Wang started working for Agilent Technologies Inc. as a FTIR application Engineer in 2013, providing pre-&amp;post-sale application support. The products he covers from Bench-top FTIR microscopes to various Mobile FTIR spectrometers. Dr. Wang received his PhD of analytical chemistry from Duke University in 2004, doing dynamic IR spectroscopy research. Then he joined Fitzpatrick Center for Photonics at Duke University, doing Tissue Raman spectrometer instrumentation. Since 2007, Dr. Wang worked for Avery Dennison Corp. as a spectroscopist, providing molecular analytical support to the research &amp; development.</p></blockquote>

Agilent Technologies: Measurement of Content Uniformity Using the TRS100 Quantitative Pharmaceutical Analysis System

Measurement of Content Uniformity Using the TRS100 Quantitative Pharmaceutical Analysis System

The Agilent TRS100 Raman system is ideal for fast assay of tablets, capsules, and other dosage forms.

TRS100 Quantitative Pharmaceutical Analysis System

<p><strong>Fourier transform infrared (FTIR) spectroscopy is a well-established and powerful instrumental technique, with FTIR analysis providing detailed information on the composition of solid, liquid, and gaseous samples. Developing models for FTIR quantitative analysis is simple using the a Cary 630 FTIR spectrometer and MicroLab FTIR software.</strong></p><blockquote><p><strong>Presenter: </strong>Yanqia Wang, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)</p><p>Dr. Yanqia Wang started working for Agilent Technologies Inc. as a FTIR application Engineer in 2013, providing pre-&amp;post-sale application support. The products he covers from Bench-top FTIR microscopes to various Mobile FTIR spectrometers. Dr. Wang received his PhD of analytical chemistry from Duke University in 2004, doing dynamic IR spectroscopy research. Then he joined Fitzpatrick Center for Photonics at Duke University, doing Tissue Raman spectrometer instrumentation. Since 2007, Dr. Wang worked for Avery Dennison Corp. as a spectroscopist, providing molecular analytical support to the research &amp; development.</p></blockquote>

Agilent Technologies: Optimize your FTIR, UV-Vis-NIR, Raman, Imaging, and Fluorescence Workflows

Quantitation Modeling for FTIR and Raman Measurements

Learn about developing models for FTIR quantitative analysis by Cary 630 FTIR spectrometer and MicroLab FTIR software.

<p><strong>Join this webinar to explore how precision analytic technologies like automated mass spectrometry are transforming fermentation in biofood production and can elevate your operations with greater efficiency, consistency and scalability.</strong></p><p>The future of food production depends on smarter, more responsive manufacturing, especially in fermentation-driven biofoods. As demand grows and sustainability pressures increase, traditional process monitoring can no longer keep pace with today’s complex production challenges.</p><p>In this webinar, you’ll discover how leading biofood manufacturers are gaining a competitive edge with Process Analytical Technology (PAT) such as automated mass spectrometry (MS). Learn how this technology is being used not only to monitor key gases in real time, but also to reduce waste, optimise yields, and strengthen process control, all without disrupting production.</p><p>You’ll also gain actionable insights into how tools like the Thermo Scientific™ Prima PRO Process Mass Spectrometer are helping producers overcome common challenges such as data lag, inconsistent batch quality and scaling inefficiencies.</p><h5><strong>Key learning points:</strong></h5><ul><li>Why mass spectrometry is quickly becoming a standard in fermentation PAT</li><li>How real-time gas analysis can dramatically improve yields and efficiency</li><li>Key considerations for implementing MS in a production setting</li><li>Lessons learned from real use cases in the biofoods space</li></ul><blockquote><p><strong>Presenter:</strong> Daniel Merriman (Product Expert for Mass Spectrometry at Thermo Fisher Scientific)</p><p>Daniel Merriman is a distinguished process analytics expert with a robust 35-year tenure that commenced at VG Instruments and seamlessly transitioned into his current role at Thermo Fisher Scientific. His extensive experience spans from intricate technical developments to strategic market leadership, underpinning his deep expertise in mass spectrometry—a vital tool in pioneering biofood production. Daniel’s wealth of knowledge makes him an indispensable voice in the webinar, poised to unpack the intricacies of collagen fermentation with the insight that only decades of front-line experience can provide.</p></blockquote>

New Food Magazine: Fermentation elevated: precision analytics with mass spectrometry in the biofood revolution

Fermentation elevated: precision analytics with mass spectrometry in the biofood revolution

Join webinar to explore how precision analytic technologies (automated mass spectrometry) are transforming fermentation in biofood production

Precision Fermentation Analytics with Mass Spectrometry

<p><strong>In this presentation, Bureau Veritas will showcase the successful development of gas chromatography solutions for analyzing trace impurities in fuel cell-grade hydrogen, in collaboration with Agilent Technologies. We will explore the role of gas chromatography in detecting these impurities, review the specific contaminants that must be identified to meet hydrogen product specifications, and examine the various analytical techniques employed to perform these analyses.</strong></p><h5><strong>Key Learning Objectives:</strong></h5><ul><li>Learn why hydrogen analysis is important</li><li>Learn which impurities are important to identify in hydrogen analysis</li><li>Learn techniques necessary to analyze these impurities</li></ul><h5><strong>Who Should Attend:</strong></h5><ul><li>Laboratory managers</li><li>Chromatographers</li><li>New product developers</li></ul><blockquote><p><strong>Presenter: </strong>Senia McPherson, C.E.T (Manager, Compositional Laboratory Fuels Division, Bureau Veritas)</p><p><strong>Presenter: </strong>Shannon Coleman (GC Application Scientist, Agilent)</p><p><strong>Presenter: </strong>Melissa O'Meara (Forensic Science Consultant, C&amp;EN Media Group)</p></blockquote>

C&EN: Analysis for Impurities in Fuel Cell Grade Hydrogen by Gas Chromatography

Analysis for Impurities in Fuel Cell Grade Hydrogen by Gas Chromatography

Discover GC solutions for detecting trace impurities in hydrogen fuel, developed by Bureau Veritas with Agilent. Learn key techniques and specs for H₂ purity.

Analysis for Impurities in Fuel Cell Grade Hydrogen by GC

<p><strong>Join us for an enlightening webinar series designed to empower academicians and researchers by exploring the latest advancements and opportunities in pharmaceutical sciences. At Agilent, we recognize the unique challenges faced by academicians, researchers, and students. At PharmaFrontiers, we have curated a series of content tailored to address your needs and unlock new opportunities.</strong></p><p>The PharmaFrontiers seminar series is designed to provide you with valuable knowledge, insights, and practical skills.</p><p><strong>Topics to be covered:</strong></p><ul><li>Integrated Spectroscopic Automation: Advancing Research and Analysis through UV-Vis, IR, and Raman Technologies.</li><li>Ensuring Safety and Regulatory Compliance in Pharmaceuticals with Elemental Spectroscopy.</li></ul><blockquote><p><strong>Presenter:</strong> Ms. Vijaya Jyothi (Product Specialist - Spectroscopy, Agilent Technologies)</p><p>Vijaya Jyothi is a seasoned product specialist at Agilent Technologies. She manages the spectroscopy division, having extensive expertise in spectroscopy applications across diverse industries, offering deep insights and solutions tailored to varied analytical needs.</p><p><strong>Presenter:</strong> Mr. Rajwar Chandra (Product Specialist - Spectroscopy, Agilent Technologies)</p><p>Chandra Rajwar is currently workingas a product specialistfor Spectroscopy Technologies with Agilent India. He has more than 20 years’ experience inanalyticalinstrumentationsales&amp; application workflow development. Rajwar is instrumental in the development of new methods and applications, as well as providing training and educational activities for prospects across various sectors onanalyticalequipment technologies.</p></blockquote>

Agilent Technologies: Pharma Frontiers Live Webinar Series: Analytical Techniques, Advances in Chromatography and Regulatory Compliance

Ensuring Excellence: Cutting-Edge Techniques for Pharmaceutical Analysis [Spectroscopy]

Explore UV-Vis, IR, and Raman automation in pharma research. Learn how elemental spectroscopy ensures safety and regulatory compliance in analysis.

Pharmaceutical Analysis by spectroscopy techniques

<p><strong>Join us on Wednesday, July 30, 2 p.m. EST, for a session on how automation is revolutionizing solid phase extraction (SPE) workflows across diverse analytical applications.</strong></p><h5><strong>Featured Talks:</strong></h5><ul><li>"Optimizing SPE Sample Preparation: Automation Strategies for Diverse Sample Volumes and Matrices" – Sebastian Wierer, Product Manager Robotics, LCTech GmbH</li><li>"Automating Solid Phase Extraction Methods: From Fields to Pharmacy" – Fred Foster, Applications Scientist, GERSTEL, Inc.</li></ul><h5><strong>Topics include:</strong></h5><ul><li>Chloramphenicol in honey</li><li>Psilocin in serum and urine</li><li>PPCPs &amp; 6-PPDQ in water samples</li><li>Acidic pesticides in potable water</li><li>Drugs of abuse in blood</li></ul><blockquote><p><strong>Presenter:</strong> Fred Foster (Applications Scientist, GERSTEL, Inc.)</p><p><strong>Presenter: </strong>Sebastian Wierer (Produt Manager Robotics, R&amp;D, LCTech GmbH)</p></blockquote>

GERSTEL: Smart Sample Preparation: Automated SPE for All Areas of Analytical Chemistry

Smart Sample Preparation: Automated SPE for All Areas of Analytical Chemistry

Join us for a session on how automation is revolutionizing solid phase extraction (SPE) workflows across diverse analytical applications.

Smart Sample Preparation - Automated SPE

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Join this free best practices webinar under the motto "Successful with Chromeleon Software!". This webinar is specifically designed for users who want to further develop and optimize their skills in handling the Thermo Scientific Chromeleon chromatography data system. Goal of this session is to provide you with practical insights and valuable tips so that you can fully exploit the potential of the Chromeleon CDS.</strong></p><h5><strong>Topics:</strong></h5><p><strong>1. The new way of eWorkflows</strong>: Discover the latest developments in the field of eWorkflows. We will show you how to optimize and automate your workflows with the latest features of Chromeleon CDS. Learn how to save time, increase accuracy of your analysis, and maximize efficiency of your laboratory processes through the use of eWorkflows.</p><p><strong>2. Easy peak integration:</strong> Peak integration is a central task in data analysis with Chromeleon CDS. In this section of the webinar, you will learn how to integrate peaks quickly and accurately. We will introduce proven methods and techniques that will help you simplify and improve your data analysis processes. Discover how to achieve consistent and reliable results with the integrated tools in Chromeleon software.</p><h5><strong>Reasons to attend:</strong></h5><ul><li>Receive practical tips and tricks from our Chromeleon experts</li><li>Learn about the latest features and updates of Chromeleon CDS</li><li>Improve your efficiency and accuracy in using Chromeleon software</li><li>Take the opportunity to ask questions</li></ul><h5><strong>Who should attend:</strong></h5><p>This webinar is aimed to all Chromeleon users who want to deepen their knowledge and optimize their workflows. Whether you are a beginner or experienced user - this webinar offers valuable information for everyone.</p><p><i>Can´t attend on July 31? Please register anyway to automatically receive the link to the webinar recording.</i></p><blockquote><p><strong>Presenter: </strong>Michele Musu (Technical Sales Specialist for Chromatography and Mass Spectrometry Software, Thermo Fisher Scientific)</p><p><strong>Presenter: </strong>Zoe Julian (Product Marketing Manager, Thermo Fisher Scientific)</p><p>Zoe Julian is a product marketing manager for chromatography and mass spectrometry software at Thermo Fisher Scientific.</p><p>With over 12 years' experience of working with chromatography and mass spectrometry techniques with a background in GC and GC-MS(/MS) organic environmental analysis, she has helped many laboratories and industries improve their workflows through a unique understanding of their challenges. Transitioning to a focus on Chromeleon CDS she has shown customers how software solutions can improve their productivity and support their day-to-day operations.</p></blockquote></div></div></div>

Thermo Fisher Scientific: eWorkflows and peak integration in Chromeleon CDS software

eWorkflows and peak integration in Chromeleon CDS software

Webinar is designed for users who want to further develop and optimize their skills in handling the Thermo Scientific Chromeleon chromatography data system

<p><strong>Raman spectroscopy delivers powerful chemical insights about reaction dynamics, blending processes, and material characterization, yet remains underutilized in many industrial settings. While complementing traditional FTIR techniques used in laboratories worldwide, modern Raman systems provide comparable qualitative and quantitative chemical information with significantly improved ease of use. Today's Raman instruments feature streamlined startup procedures, intuitive data interpretation, and superior capabilities for production integration and in situ measurements.</strong></p><p>In this webinar, Dr. Adam J. Hopkins of Metrohm USA will demonstrate how Raman spectroscopy offers practical solutions for both quantitative and qualitative applications in routine analysis environments. The presentation will explore real-world case studies including polymer functionalization monitoring, carbon material characterization, and rapid chemical quantification systems that don't require microscopy. These examples illustrate how Raman technology has transformed from complex, expensive instrumentation into accessible, compact, and cost-effective tools suitable for everyday analytical needs.</p><h5><strong>Who should attend?</strong></h5><ul><li>Quality control or assurance mangers/directors</li><li>Process Development Scientists/Engineers</li><li>Industrial and Academic Research chemists</li><li>Anyone interested in learning about Raman spectroscopy</li></ul><h5><strong>Key learning points</strong></h5><ul><li>Understand how Raman spectroscopy directly reveals molecular structure information at the point of need, providing immediate chemical insights without complex sample preparation</li><li>Discover how Raman spectroscopy bridges the gap between laboratory development and production implementation with probe-based solutions that provide identical chemical information across environments.</li><li>See how modern Raman technology makes powerful chemical analysis accessible to researchers, engineers, and quality technicians alike</li><li>Understand the critical factors for selecting appropriate Raman instrumentation based on your specific application needs</li></ul><blockquote><p><strong>Speaker: </strong>Dr. Adam J. Hopkins (Spectroscopy Product Manager, Metrohm USA)</p><p>Dr. Adam J. Hopkins is the Spectroscopy Product Manager for handheld and laboratory instruments at Metrohm USA since 2016. He has a Ph.D. in chemistry from the University of Oregon where he studied nonlinear optical spectroscopy under Geraldine Richmond. Between graduate school and Metrohm, Adam worked developing spectroscopic solutions for standoff and noncontact sensing applications using LIBS, Raman, and other novel techniques. Dr. Hopkins is a member of the American Chemical Society, Society for Applied Spectroscopy, Coblentz Society, and SPIE. He is the author of over 20 peer-reviewed papers and proceedings and three patents.</p></blockquote>

Metrohm: Practical Raman Applications: From Polymers to Process Control

Practical Raman Applications: From Polymers to Process Control

Learn how Raman spectroscopy bridges lab and production with fast, reliable chemical analysis—ideal for QC, R&D, and process control applications.

Raman Applications: From Polymers to Process Control

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>We are thrilled to welcome you to a special event highlighting the use of separation science and chromatographic techniques in forensic applications. Chromatography has long been a tool exploited in the justice sector by providing key chemical information that can be used in legal proceedings. New developments in research highlight the continual evolution of chromatography’s fit-for-purpose in the criminal justice system.</strong></p><p>During this event, we will hear from two experts in forensic science who will highlight their research in different applications of chromatography for novel forensic analyses.</p><p>We hope this event will celebrate the past, present, and future of separation technology in forensic science and promote new ideas for future work.</p><h4><strong>Registration</strong></h4><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://us02web.zoom.us/webinar/register/7417525819836/WN_6vtYkWdHSPqK5rVzbaqTXg#/registration"><strong>Register here</strong></a></p></blockquote><p>This is a <strong>FREE webinar</strong>. After registering, you will receive a confirmation email containing information on how to join the webinar. <strong>Registrations with academic institutional email addresses will be prioritized.</strong></p><p><strong>Certificates of attendance will be delivered to those who attend the live webinar.</strong></p><p>Can’t attend? Register anyway and we’ll let you know when the recording is available to watch.</p><h4><strong>Program</strong></h4><h5><strong>3:00 - 3:10 pm Chair Introduction</strong></h5><ul><li>Dr. Katelynn Perrault Uptmor (Chair)</li></ul><h5><strong>3:10 - 3:30 pm An Improved method for xylazine in postmortem casework using GC/MS</strong></h5><ul><li>Dr. Karen Scott</li></ul><h5><strong>3:30 - 3:50 pm Development of a GC-TOFMS-Based Model for Estimating Fingerprint Age Under Varying Light Exposure Conditions</strong></h5><ul><li>Dr. Petr Vozka</li></ul><h5><strong>3:50 - 4:05 pm Q&amp;A</strong></h5><h5><strong>4:05 - 4:10 pm Closing of Webinar</strong></h5><ul><li>Dr. Katelynn Perrault Uptmor (Chair)&nbsp;&nbsp;&nbsp;&nbsp;</li></ul><blockquote><p><strong>Event Chair:</strong> Dr. Katelynn A. Perrault Uptmor (Department of Chemistry, William &amp; Mary, Williamsburg, Virginia, USA)</p><p>Dr. Katelynn Perrault Uptmor is Assistant Professor of Chemistry at William and Mary (W&amp;M) and the Principal Investigator of the Nontargeted Separations Laboratory. She obtained her PhD from the University of Technology, Sydney, Australia, and performed a Postdoctoral Fellowship at the University of Liège in Belgium. She also worked as a faculty member at Chaminade University of Honolulu in the Forensic Sciences/Chemistry program from 2017 to 2023, before coming to W&amp;M in August 2023. Her research group comprises undergraduate and master's research students in analytical chemistry. Her research focuses on using comprehensive two-dimensional gas chromatography (GC×GC) in forensic and food applications.</p><p><strong>Presenter: </strong>Dr. Karen Scott (Department of Pathology, University of Alabama at Birmingham, USA)</p><p>Dr Karen Scott is the Director of the Forensic Toxicology and Clinical Toxicology Laboratory in the Division of Laboratory Medicine at the University of Alabama at Birmingham. She also holds an Associate Professor of Laboratory Medicine post in the Department of Pathology at the same University. She has over 30 years of experience in the fields of forensic and clinical toxicology and is published in the areas of post-mortem and human performance toxicology, as well as hair and alternative matrix testing. She is a reviewer for three of the main Forensic Toxicology journals and is on the editorial board for Separations (Forensics/Toxins section). Dr. Scott has a Bachelor of Science degree in Forensic and Analytical Chemistry from the University of Strathclyde (Glasgow, UK, 1994) and a PhD in Forensic Toxicology from the University of Glasgow (UK, 1998). On completion of her degrees, she carried out postdoctoral research in Tokyo, Japan, investigating the incorporation rates of drugs into hair. Dr. Scott has been a member of the Alcohol, Drugs, and Impairment Division of the National Safety Council since 2015 and is on the executive board of this organization. She is also on the editorial board of Clarkes Analysis of Drugs and Poisons and is a member of the OSAC Forensic Toxicology subcommittee.</p><p><strong>Presenter:&nbsp;</strong>Dr. Petr Vozka (Department of Chemistry and Biochemistry, California State University, Los Angeles)</p><p>Dr. Petr Vozka is an Associate Professor of Analytical Chemistry at California State University, Los Angeles (CSULA), where he also directs the Complex Chemical Composition Analysis Laboratory (C3AL). His research lies at the forefront of multidimensional chromatography and mass spectrometry, with a primary focus on developing advanced analytical techniques, especially GC×GC-FID and GC×GC-TOFMS, for characterizing complex mixtures, including products from plastic waste conversion, fingerprints, and organic pollutants adsorbed on microplastics. He has over 30 peer-reviewed publications, a book chapter, one patent, and over 50 conference presentations, including 10 invited talks and a keynote address at the 14th Multidimensional Chromatography Workshop (MDCW 2023), where he now serves as co-chair. He also organizes the GC×GC symposium at ACS Fall Meetings (since 2023) and hosted the 15th MDCW on the CSULA campus in 2024.</p></blockquote></div></div></div>

Sciforum: Developments in Chromatographic Separations for Forensic Analysis

Developments in Chromatographic Separations for Forensic Analysis

Join forensic experts to discover how GC and GC-TOFMS are used for xylazine detection and fingerprint aging. Free webinar on chromatographic tools in forensics.

Chromatographic Separations for Forensic Analysis

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>LC-MS and GC-MS datasets can be challenging to process and extract meaningful information from. However, when correctly executed, these techniques can be unmatched for detecting unknown components or monitoring known ones.</strong></p><p>Learn how Wiley's NEW KnowItAll LC Expert and MS Expert can help reduce barriers to LC-MS and GC-MS processing and data analysis by automating identification of unknown compounds. By combining fast, flexible deconvolution into a single workflow with database search of Wiley’s comprehensive, trusted spectral libraries, KnowItAll can improve your workflow and save hours of manual analysis time.</p><p>Join us to see these exciting new technologies through a series of real-world examples. A live Q&amp;A will follow the presentation, providing an opportunity for you to submit your questions to be answered by Wiley's experts.</p><h5><strong>By attending this webinar, you will learn how to:</strong></h5><ul><li>Automate the identification of unknown compounds to streamline your analysis workflows</li><li>Access over 8.5 million quality spectra for reliable and comprehensive spectral matching</li><li>Integrate seamlessly with existing systems using a vendor-neutral platform for maximum flexibility</li><li>Explore the full capabilities of KnowItAll LC Expert and MS Expert through a series of real-world examples</li></ul><h5><strong>About KnowItAll Software</strong></h5><p>KnowItAll offers a unified, vendor-neutral solution for data processing, analysis, searching, and databasing. KnowItAll 2025 has tools for workflows IR, Raman, GC-MS, LC-MS, NMR, and UV-Vis, as well as tools for structure drawing, report publishing, and more.</p><h5><strong>Who should attend:</strong></h5><ul><li>Those who regularly perform LC-MS or GC-MS (or both) in their laboratories.</li></ul><blockquote><p><strong>Presenter: </strong>Nadia Laschuk (Product Manager, New Techniques, Wiley Science Solutions)</p><p>Dr. Nadia Laschuk is a Product Manager for Wiley Science Solutions, where she oversees the development of new products and databases, while supporting existing KnowItAll capabilities. She earned her Ph.D. in Materials Science from Ontario Tech University, where she executed chemistry research using a variety of instrumental analytical techniques. Since joining Wiley in 2022, Nadia has focused on cheminformatics and software development.</p><p><strong>Presenter: </strong>Michelle D’Souza (Product Manager, &nbsp;Software Products, Wiley Science Solutions)</p><p>Dr. D’Souza brings years of insight and knowledge in the area of spectral informatics with leadership roles at both Wiley and Bio-Rad Laboratories. In addition to her multiple years as a scientific researcher at Abbott (now AbbVie) and DuPont, she has a Ph.D. in Chemistry from Northern Illinois University and a Master's in Analytical Chemistry from the Chinese Academy of Preventive Medicine. She earned a BS degree from the Chemistry Department of Beijing University. &nbsp;</p></blockquote></div></div></div>

SeparationScience: Automate Non-Targeted LC-MS/MS and GC-MS Component Identification

Automate Non-Targeted LC-MS/MS and GC-MS Component Identification

Learn how KnowItAll LC & MS Expert tools help automate unknown ID and enhance LC-MS/GC-MS analysis using Wiley’s spectral libraries.

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