<p><strong>Researchers</strong><span><strong>&nbsp;</strong></span><strong>Tereza Nešporová and Jaroslava Večerková from Brno's </strong><span><strong>RECETOX</strong></span><strong> explain why failures are also a valuable part of gaining knowledge, how they study the effects of chemical substances on the hormonal system, and why they apply their professional insights to their everyday lives.</strong></p><h5><strong>How did you get involved in research at RECETOX?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span> <span>I actually joined RECETOX by chance during my follow-up Master's studies in Environmental Chemistry, back when Professor Holoubek was still leading the institute. I wrote my thesis under Klára Hilscherová and simply stayed here ever since, except for a break during maternity leave. I have been part of her team the whole time, focusing on endocrine disruptors.&nbsp;What has changed over the years is the focus of our research. We used to study surface waters, particularly the presence of substances with endocrine-disrupting potential and their effects on organisms. Today, the research has shifted more toward humans and the interactions between chemical substances and the endocrine system.&nbsp;</span></p><p><span><strong>Tereza:</strong></span><strong> </strong><span>I came from a completely different field. I studied molecular biology and worked on chronic lymphocytic leukemia for my Master's thesis at CEITEC. I used genetic engineering methods such as CRISPR/Cas9 for gene editing—activating, suppressing, or completely removing genes.&nbsp;At the time, Klára Hilscherová’s group needed to create cellular models with increased production of deiodinase enzymes, which I still work on today. I had heard only positive things about the team, and when I finished my Master's degree, I wanted to move beyond my original field. The connection between hormones and neurodevelopment attracted me, and RECETOX became the obvious choice.&nbsp;</span></p><h5><strong>So you are in the same research team. How do you collaborate?&nbsp;</strong></h5><p><span><strong>Tereza:</strong></span><strong> </strong><span>We sit in the same office. And that’s probably the main thing (laughs).&nbsp;</span></p><p><span><strong>Jaroslava:</strong></span> <span>We discuss things a lot. Some mechanisms repeat across experiments, so we talk about how each of us evaluates data and why. We inspire each other, even though we do not directly collaborate on the same laboratory work.&nbsp;</span></p><h5><strong>How does your work differ?&nbsp;</strong></h5><p><span><strong>Tereza:</strong></span><strong> </strong><span>Our team is highly interconnected. We all work on developing assays for detecting endocrine-disrupting substances, specifically those affecting thyroid hormones. However, each of us focuses on a different part of the system.&nbsp;I focus on deiodinase enzymes, which regulate the activation and deactivation of hormones. Recently, I have been spending more time analyzing data and designing experiments than working directly in the laboratory.&nbsp;</span></p><p><span><strong>Jaroslava:</strong></span><strong> </strong><span>Within the team, I mainly participate in testing different types of samples—from individual chemicals and mixtures to real environmental samples such as household dust—using the assays mentioned above.&nbsp;It is important to note that chemicals can affect the hormonal system at different levels. They can bind to or block nuclear receptors, affect hormone transport in the bloodstream, or interfere with hormone metabolism. In the past, only one part of this process was monitored. Today, we aim to cover the full spectrum of these interactions.&nbsp;</span></p><p><span><strong>Tereza:</strong></span><strong> </strong><span>And that is crucial. A substance may appear negative in one test, yet affect another part of the system, producing a significant impact on the organism. That is why current research focuses on the entire range of possible mechanisms.&nbsp;</span></p><h5><strong>Why did you choose endocrine disruptors as your research topic?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span> <span>For me, it was more or less a coincidence while choosing my thesis topic. But it turned out to be a fascinating area, so I stayed with it.&nbsp;</span></p><p><span><strong>Tereza:</strong></span> <span>I had been interested in it for a long time. I also like that our work has a concrete outcome—we develop tests that can realistically be used in decision-making regarding the safety of chemical substances. Compared to my previous research, I feel this work has a much more direct application.&nbsp;</span></p><h5><strong>What about your PhD studies?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span><strong> </strong><span>My PhD studies are currently on hold. After maternity leave, I returned as a laboratory technician, and my project work gradually shifted away from my original doctoral topic.&nbsp;</span></p><p><span><strong>Tereza:</strong></span><strong> </strong><span>I am currently in the fourth year of my PhD studies. I also completed a research stay in Germany, where I learned to work with neuronal cells.&nbsp;As part of my studies, I focus mainly on deiodinases—the enzymes that act as the “on and off switches” of thyroid hormones. We are developing a test that can measure the effects of chemical substances on their activity.&nbsp;In addition, we are now studying how these substances affect neurons and their development, because proper thyroid hormone levels are crucial for nervous system development.&nbsp;</span></p><h5><strong>What is the most challenging aspect of laboratory work?&nbsp;</strong></h5><p><span><strong>Tereza:</strong></span><strong> </strong><span>Probably unpredictability. Cells do not always grow as expected, instruments have their bad days, and human error also plays a role. The important thing is to document all mistakes and complications and learn from them.&nbsp;</span></p><p><span><strong>Jaroslava:</strong></span> <span>I agree with Tereza. The biggest challenge is unpredictability. Cells are living systems and do not always behave the same way.&nbsp;</span></p><h5><strong>Can a career in science be combined with parenthood?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span> <span>At RECETOX, definitely. There is a great deal of flexibility, and managers are very supportive. When necessary, it is possible to work from home. We help each other a lot within the team.&nbsp;</span></p><p><span><strong>Tereza:</strong></span> <span>It also depends on the type of work and whether it can be planned according to your needs. Our team collaborates closely and tries to help one another whenever necessary. That is key. And when needed, data analysis and manuscript writing can also be done from home.&nbsp;</span></p><h5><strong>Is your work more routine or highly varied?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span> <span>Very varied. Laboratory work alternates with computer-based work. We are constantly learning new things. It is definitely not repetitive or boring, and that is what I enjoy about it.&nbsp;</span></p><p><span><strong>Tereza:</strong></span> <span>The only routine in my work is taking care of cell cultures. Otherwise, the work is constantly changing. That is also what I enjoy most about it.&nbsp;</span></p><h5><strong>What are the biggest challenges in your work?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span> <span>Data evaluation. Measuring something is one thing; evaluating and interpreting it correctly is another.&nbsp;</span></p><p><span><strong>Tereza:</strong></span> <span>Implementing new methods. And also those moments when you do everything correctly according to a published protocol, yet the results still do not match expectations.&nbsp;In science, you have to learn to accept that not everything works the first time. The important thing is not to give up, to continue optimizing, and to keep hoping for success.&nbsp;</span></p><h5><strong>What role should open science play?&nbsp;</strong></h5><p><span><strong>Tereza:</strong></span><strong> </strong><span>A huge one. If we had access to detailed protocols and original datasets, it would save enormous amounts of time and money during the implementation and optimization of new methods. Scientific papers often omit details that are actually critical for experimental success.&nbsp;</span></p><p><span><strong>Jaroslava:</strong></span><strong> </strong><span>It is also important to share failures. A negative result is still a result, and it can provide valuable information.&nbsp;</span></p><h5><strong>You are both mothers. Does your work influence your personal lives?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span><strong> </strong><span>Absolutely. For example, we pay close attention to washing fruit because of chemical treatments. I encourage my children to think about what they consume, what it contains, and where it comes from. We try to avoid plastics and consistently separate waste.&nbsp;</span></p><p><span><strong>Tereza:</strong></span> <span>Definitely. Even before having a child, I paid close attention to the composition of cosmetics, food, and other products. After becoming a parent, my caution multiplied.&nbsp;I was especially careful during pregnancy because a developing organism is most sensitive to harmful substances. Sometimes relatives raise their eyebrows at this, but when we have information firsthand, we cannot simply ignore it.&nbsp;</span></p><p><span><strong>Jaroslava:</strong></span> <span>We also pay attention to toys, clothing, and materials used in the home. It is a kind of professional deformation (laughs).&nbsp;</span></p><h5><strong>How can your research contribute from a broader perspective? How can others build upon it?&nbsp;</strong></h5><p><span><strong>Jaroslava:</strong></span> <span>We are gradually optimizing methods that may eventually be used routinely. That is probably our greatest contribution.&nbsp;</span></p><p><span><strong>Tereza:</strong></span> <span>Yes, our methods could help identify undesirable effects of substances before they reach the market, potentially leading to regulation of their production.&nbsp;</span></p><h5><strong>Would you like to continue working on this topic in the future?&nbsp;</strong></h5><p><span><strong>Jaroslava Večerková:</strong></span><strong> </strong><span>The topic of endocrine disruption is extremely interesting and very broad. The direction of research may change depending on current projects, but I would like to remain part of the team.&nbsp;</span></p><p><span><strong>Tereza Nešporová:</strong></span> <span>I am very interested in uncovering how substances affect human health, and I believe I will want to continue working in this area. I like how dynamic the research is and that it has direct practical applications. I do not mind change, but I am happy within this team and would like to stay. We work together as a well-coordinated group.&nbsp;</span></p>

Researchers Tereza Nešporová and Jaroslava Večerková: In science, we must learn to work with failure

<p><strong>Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning, today announced the release of the multi-format </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2461"><i><strong>NIST / EPA / NIH EI Mass Spectral Library 2026</strong></i><strong> </strong></a><strong>and </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2462"><i><strong>NIST MS/MS Spectral Library 2026</strong></i></a><strong>.</strong></p><p>Developed by the experienced mass spectrometry (MS) team at the National Institute of Standards and Technology (NIST), these databases represent the culmination of more than four decades of comprehensive evaluation and expansion, making it an essential resource for those analyzing mass spectra.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_NIST_EPA_NIH_EI_Mass_Spectral_Library_2026_af64f091bd.jpg" alt="Wiley: NIST / EPA / NIH EI Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_NIST_EPA_NIH_EI_Mass_Spectral_Library_2026_af64f091bd.jpg 111w," sizes="100vw" width="1531" height="2159"></p><h4><strong>New in the 2026 release:</strong></h4><ul><li>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2461"><i><strong>NIST/NIH/EPA EI Mass Spectral Library</strong></i></a> includes <strong>35,000+ new compounds</strong>, bringing the total to <strong>431,000+ EI (electron ionization) spectra</strong>, with expanded coverage of biologically, environmentally, and industrially relevant compounds.</li><li>The <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/2462"><i><strong>NIST MS/MS Mass Spectral Library</strong></i></a> now contains <strong>3.2 million+ spectra</strong> across <strong>68,600+ compounds</strong>, spanning metabolites, drugs, pesticides, peptides, lipids, glycans, extractable and leachable compounds, surfactants, and contaminants.</li><li>The<i> <strong>GC Retention Index Library </strong></i>added over <strong>35,000 compounds</strong>, further enhancing compound identification workflows.</li><li>The underlying <strong>NIST MS Search software</strong> has also been extensively updated and now includes chromatogram analysis for GC-MS or LC-MS/MS workflows.</li><li><strong>From 2026, the EI and MS/MS libraries are available as separate products</strong>. Both can be ordered through Wiley, with bundle options available.</li></ul><p>“<i>Wiley distributes NIST EI 2026 in more instrument formats than any other NIST 2026 provider,</i>” said Graeme Whitley, Senior Director, Data Science Solutions at Wiley. “<i>In addition to the standalone NIST libraries, Wiley also offers customers the option to extend their capabilities with the </i><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/887"><i><strong>Wiley Registry</strong> </i></a><i>and </i><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/934"><i><strong>KnowItAll GC-MS</strong></i></a><i><strong> and </strong></i><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1942"><i><strong>LC-MS libraries</strong></i></a><i>, delivering broader coverage and flexibility for evolving analytical workflow needs.</i>”</p><p>The EI library is available in multiple instrumentation manufacturer formats, while the MS/MS library is provided in NIST format. Together, these libraries support high-confidence analysis across GC-MS and LC-MS workflows, helping laboratories confidently improve identification and streamline analytical processes.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_NIST_MS_MS_Mass_Spectral_Library_2026_899749d679.jpg" alt="Wiley: NIST MS/MS Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_NIST_MS_MS_Mass_Spectral_Library_2026_899749d679.jpg 110w," sizes="100vw" width="1526" height="2160"></p><h5><strong>Learn more at Wiley Science Solutions:</strong></h5><ul><li>Visit our web for more information about the <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/gc-ms/nist-epa-nih-mass-spectral-library/"><i><strong>NIST/EPA/NIH EI Mass Spectral Library 2026</strong></i></a></li><li>Visit our web for more information about the <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/solutions/technique/lc-ms/nist-ms-ms-mass-spectral-library-2026/"><i><strong>NIST MS/MS Mass Spectral Library 2026</strong></i></a></li></ul><h5><strong>About Wiley</strong></h5><p>Wiley is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning.&nbsp;</p>

Wiley Releases NIST Mass Spectral Library 2026 in Multiple Instrument-Ready Formats

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 6th July 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you brochure by <strong>Agilent Technologies, </strong>presentation by <strong>MDCW / University of Washington </strong>and posters by <strong>Shimadzu / ASMS</strong> and <strong>Thermo Fisher Scientific</strong> <strong>/ ASMS!</strong></p><h3><strong>1. Agilent Technologies: Operational efficiency for your GC and GC/MS labs with the Agilent 8860B gas chromatography system</strong></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/br_8860b_gc_5994_9206en_agilent_7b7b766cd2.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>The brochure presents the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8860B"><strong>Agilent 8860B GC system</strong></a> as a routine GC and GC/MS platform focused on operational efficiency, reliable performance, intelligent diagnostics, and sustainability. It is positioned as a next-generation GC workhorse for laboratories that need consistent, high-quality data while increasing throughput and reducing downtime. Key performance features include dual sample injection capabilities, improved repeatability for retention time and peak area, electronic pneumatics control, retention time locking for method transfer, and a built-in oven light to simplify maintenance and column installation.</p><p>A major theme is <strong>instrument intelligence</strong> through the Agilent GC Assist interface. The system provides browser-based access to instrument status, methods, sequences, logs, diagnostics, maintenance information, and help resources. Built-in tools such as early maintenance feedback, system health reporting, automated and user-initiated diagnostics, peak evaluation, and self-guided troubleshooting are designed to help laboratories detect issues early, maintain uptime, and reduce the need for expert-level intervention during routine operation.</p><p>The brochure also emphasizes <strong>sustainability and resource management</strong>. The 8860B GC includes gas and power usage reporting, method-based monitoring, alerts for abnormal gas use, and tools for detecting possible leaks or restrictions. Agilent highlights helium conservation options, including a helium conservation module that can reduce helium consumption by switching to an alternative gas during idle periods, as well as support for hydrogen and nitrogen carrier gases with built-in hydrogen safety features. These functions are presented as ways to reduce operating costs, conserve resources, and protect workflows from helium supply disruptions.</p><p>Finally, the brochure describes the broader <strong>Agilent GC ecosystem</strong> around the 8860B. The system supports multiple inlets, detectors, autosamplers, headspace sampling, single quadrupole GC/MS compatibility, OpenLab CDS, DA Express, MassHunter software, Agilent consumables, columns, and CrossLab services. Together, these elements are presented as a complete workflow for routine laboratories that need flexibility, compliance support, service coverage, method consulting, training, and long-term value from their GC investment.</p><h3><strong>2. MDCW / University of Washington: Implementing Tile-Based Fisher Ratio Analysis of GC×GC-TOFMS Data to Obtain a Master Peak Table of All Detected Analyte Compounds in Many Petroleum-Based Samples</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_9_Halvorsen_136808e314.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>The presentation describes the development of a chemometric workflow for advanced fuel sample analysis using GC×GC-TOFMS data. The work was carried out by the University of Washington in collaboration with Chevron Technical Center, with the goal of improving the characterization of complex petroleum-based samples. Moving from conventional GC to comprehensive two-dimensional GC increased peak capacity and chromatographic resolution, but also created the need for more advanced methods to generate reliable peak tables across many chemically diverse fuel samples.</p><p>The key method presented is a tile-based Fisher Ratio approach implemented through <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/348"><strong>ChromaTOF Tile</strong></a><strong>.</strong> This method identifies analytes that show statistically significant concentration differences between sample classes. Instead of relying only on peak detection or manual alignment, the workflow uses chromatographic “tiles” to reduce the impact of retention-time shifting and to capture both major and trace-level components. The study included multiple fuel classes, including hydrobate, reformate, naphtha, FCC gasoline, and blanks.</p><p>Because Fisher Ratio values alone do not directly indicate whether a compound is truly detectable, the authors added a blank-based p-testing strategy. Three blank chromatograms were used to estimate background signal distributions for each tile, and confidence intervals were then applied to determine whether each detected hit was present in individual sample classes. This produced a master peak table covering 719 hits across nine fuel sample classes. The results showed good reproducibility, with only 6.3% of classifications being heterogeneous across replicates.</p><p>Overall, the presentation concludes that the tile-based workflow can generate comprehensive and reproducible peak tables with reduced user intervention, while preserving the ability to recover trace analytes in complex petroleum samples. The approach should be broadly applicable to other complex sample types and could also be adapted using chemometric metrics other than Fisher Ratio, depending on the experimental design and analytical goals.</p><h3><strong>3. Shimadzu / ASMS: Is Your Next Sip Safe? A Simple, Rapid Method for Measuring volatile PFAS in Juices.</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/TP_143_Is_Your_Next_Sip_Safe_A_Simple_Rapid_Method_for_Measuring_volatile_PFAS_in_Juices_a6ed9414c0.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Per- and polyfluoroalkyl substances (PFAS) pollution is a growing global concern due to links with adverse health effects, many of which remain poorly understood. 1 Accurate detection and quantification are therefore essential. While PFAS analysis has traditionally focused on water, attention is rapidly expanding to food and beverages, where testing remains limited despite high stakes and increasing regulations. 2 A recent PFAS lawsuit against a juice manufacturer underscored the heightened public scrutiny of PFAS in juices, placing food safety and brand reputation at risk. 3 This study presents a Headspace Solid-Phase Microextraction– Triple Quadrupole Gas Chromatography/Mass Spectrometry (HS-SPME GC/MS/MS) method for PFAS quantitation in juices. GC/MS enables analysis of volatile PFAS unsuitable for LC/MS, while HS-SPME offers rapid analysis with minimal sample preparation in complex matrices.</p><h4><strong>Methods</strong></h4><p>A volatile PFAS analysis method was developed on a <strong>Shimadzu </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ8040+NX"><strong>GCMS-TQ8040 NX</strong></a> with an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=AOC-6000+Plus"><strong>AOC-6000 Plus multifunctional autosampler</strong></a> equipped with a solid phase microextraction (SPME) module (Figure 1).</p><h4><strong>Results&nbsp;</strong></h4><p>The system was deemed free of contaminants and inferences. None of the target PFAS in the method blank were found in quantifiable concentration. In the study, the calibration curve for each target included at least seven calibrators. Calibration curve results showed a good linear fit for all compounds with coefficient of determination (R2 ) ≥ 0.993. The linear range and R2 of each PFAS target are shown in Table 3.</p><h4><strong>Conclusion</strong></h4><p>Overall, these results demonstrate the robustness and reliability of the method for PFAS analysis in two carton apple juices (Brands X and Y), one plastic bottled apple juice (Brand X), and a berry blend carton juice (Brand X). Given the diversity of matrices evaluated, the method may also be suitable for other beverages, including sports drinks and vitamin-enhanced waters</p><h3><strong>4. Thermo Fisher Scientific / ASMS: Enhanced sensitivity for the quantitative analysis of pesticides using a GC Orbitrap MS</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_004706_lsms_pesticides_exploris_gc_efs_po004706_asms2026_na_en_5f51b18742.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Detection of pesticide residues in fruits and vegetables is essential for food safety, but it can be challenging in complex, highly pigmented matrices due to interferences. Orbitrap technology provides high resolution and mass accuracy, enabling confident identification of coeluting and isobaric compounds while reducing false results. Furthermore, the FS-HRAM acquisition enables simultaneous quantitation and screening within a single analysis with the capability of retrospective data analysis, allowing laboratories to reprocess datasets for additional or emerging compounds without re-injecting samples. The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2419"><strong>Orbitrap Exploris GC S mass spectrometer</strong></a><strong> </strong>features the Thermo Scientific NeverVent Advanced Electron Ionization Source (NVAEI) which offers an improved design providing enhanced sensitivity and robustness, allowing for increased instrument uptime and maximized sample throughput for rapid return on investment (ROI).</p><h4><strong>Materials and methods</strong></h4><h5><strong>Data analysis&nbsp;</strong></h5><p>Data was acquired, processed and reported using the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76"><strong>Thermo Scientific Chromeleon Chromatography Data System (CDS) software</strong></a>, which provides integrated instrument control, automated workflows, and an intuitive interface for data analysis, customizable reporting, and compliant data management in accordance with FDA 21 CFR Part 11 and European Commission (EU) Annex 11. Its advanced reprocessing capability streamlines sequence setup, data review, and reporting offering the possibility to easily flag and check compliance with the current regulations.</p><p>Results Compliant analyte identification The use of HRAM-GCMS reduces the matrix interferences ensuring a confident and selective identification of analytes (Figure 1). All target compounds satisfied the SANTE criteria at the default MRL of 10 µg/kg and more than 90% were confirmed at concentrations of 1 µg/kg following the SANTE/11312/2021v2026 guidance criteria of:&nbsp;</p><ul><li>two ions were detected for each pesticide with mass accuracy ≤ 5 ppm with precursor and product ions in the extracted ion chromatograms fully overlapped,&nbsp;</li><li>due to the added value of accurate mass measurement, matching ion ratios is not necessary, however, an ion ratio (IR) deviation within ± 30% (relative) of the average of calibration standards from the same sequence was considered to provide additional support for identification</li><li>retention times (RT) within a tolerance of ± 0.1 minutes</li></ul><p>Sensitivity performance (IDL) and analytical linearity Instrument sensitivity was evaluated using calculated IDLs derived from replicate injections of low-level, matrix-matched standards. The Orbitrap Exploris GC S demonstrated detection limits at levels at or below 0.5 µg/kg for most of the investigated pesticides (Figure 2). Linear dynamic range was evaluated using matrix-matched calibration curves ranging 0.5–200 µg/kg, with each calibration level injected in triplicate. All target analytes demonstrated excellent linearity, with coefficients of determination (R²) &gt; 0.993, response factor (%RSD) values below 20% across the calibration range, and ion ratios (IRs) within ±30% of the average calibration standard values. System suitability for quantitative analysis was confirmed by calculated concentrations within ±20% of expected values and recoveries ranging from 96% to 104%. An example of calibration curve for Aldrin is shown in Figure 3.</p><h4><strong>Conclusions&nbsp;</strong></h4><p>The results obtained in these experiments demonstrate that the Orbitrap Exploris GC S mass spectrometer equipped with NeverVent AEI ion source represents a reliable tool for analysis of pesticides in complex matrices.&nbsp;</p><ul><li>The Orbitrap Exploris GC S offers a simple approach for the multiresidue analysis of pesticides allowing for full-scan acquisition combined with high mass resolving power&nbsp;</li><li>The NeverVent AEI ion source is designed for ultra-trace concentration detection, making it ideal for challenging applications ensuring detection limits at levels at or below 0.5 µg/kg for most of the investigated pesticides&nbsp;</li><li>Confident identification of compounds can be easily achieved through i). high spectral quality, ii). high spectral fidelity, ensuring consistent spectrum independently from concentration, and iii). consistent mass accuracy irrespectively of analyte concentration and time&nbsp;</li><li>System suitability for quantitative analysis was demonstrated with R2 &gt;0.993, RF %RSD across the entire calibration curve &lt; 20, and IRs within ± 30% of the average of calibration standards, calculated amounts within 20% the expected values, and percentage recovery (%) ranging from 96 to 104.</li></ul></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 28, 2026

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Poster

RECETOX (Research Centre for Toxic Compounds in the Environment) is an independent department of the Faculty of Science of Masaryk University in Brno, which has been established in 1983. RECETOX is focused on the research and education in cross-cutting area of Environment and Health. It addresses interactions among chemicals, environment, and biological systems, including consequences at local, regional, and global levels.

RECETOX - Centrum pro výzkum toxických látek v prostředí

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Watrex SYRINGE FILTERS

Syringe filters (filters for syringes) are a universal tool that ensures sample purity and prevents contamination of analytical instruments.

<p><strong>Syringe filters (filters for syringes) are a universal tool that ensures sample purity and prevents contamination of analytical instruments. They are single-use filters used for precise filtration of liquids before their application or analysis.</strong></p><p><strong>Pore Size: </strong>Filters come in various pore sizes, ranging from 0.2 μm to 5 μm, depending on the required level of filtration. Smaller pores (e.g., 0.22 μm) are often used for sterilizing solutions, as they capture bacteria and other microorganisms.</p><p>We offer syringe filters in the following sizes: <strong>4 mm, 13 mm, 25 mm, and 30 mm</strong>, all available with pore sizes of <strong>0.22 μm and 0.45 μm</strong>.</p><p><strong>Filter Material:</strong> Syringe filters are made from different materials that are compatible with various sample types. It is important to select the correct filter material based on the chemical composition of the sample. We offer syringe filters made from the following materials:</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Watrex_SYRINGE_FILTRY_b6ffda00e2.jpg" alt="Watrex: Watrex SYRINGE FILTERS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Watrex_SYRINGE_FILTRY_b6ffda00e2.jpg 245w," sizes="100vw" width="1808" height="1017"></p><h4><strong>Nylon</strong></h4><ul><li>Suitable for <strong>aqueous solutions</strong> and most <strong>organic solvents</strong>.</li><li>It has strong <strong>mechanical stability</strong> and excellent chemical compatibility with <strong>esters, bases, phenols, and alcohols.</strong></li></ul><h4><strong>PTFE (Polytetrafluoroethylene)</strong></h4><ul><li>Chemically resistant to most <strong>organic solvents</strong>.</li><li>It has very broad chemical and thermal compatibility.</li><li>PTFE filters are recommended for <strong>strong acids and bases</strong> and are excellent for filtration and degassing chromatography.</li></ul><h4><strong>PVDF (Polyvinylidene fluoride)</strong></h4><ul><li>Suitable for <strong>biological samples</strong>.</li><li>It has good <strong>chemical resistance</strong> and low UV absorption.</li><li>Commonly used for filtering all water-based samples and most solvents.</li></ul><h4><strong>PES (Polyester)</strong></h4><ul><li>Ideal for <strong>water-based samples</strong>, especially <strong>biological ones</strong>, with a fast and high flow rate.</li></ul><h4><strong>MCE (Mixed Cellulose Esters)</strong></h4><ul><li>Ideal for <strong>aqueous samples</strong>, <strong>tissue cultures</strong>, and <strong>sensitive biological samples</strong>.</li><li>It has lower chemical resistance, excellent water flow, and a better cutoff effect.</li></ul><h4><strong>PP (Polypropylene)</strong></h4><ul><li>Ideal for filtering all water-based samples and most solvents.</li><li>Used for general <strong>filtration of biological samples</strong>, <strong>solvents</strong>, <strong>deionized water</strong>, and reducing biological load.</li><li>It has good thermal compatibility.</li></ul><h5><strong>Examples of Use:</strong></h5><ol><li><strong>Sterilization of solutions: </strong>Filtration can remove bacteria and other microorganisms from solutions.</li><li><strong>Sample purification: </strong>Samples are filtered before analysis to remove solid particles that could contaminate analytical instruments or affect analysis results.</li><li><strong>Preparation for chromatography:</strong> Filtration before entering devices like HPLC (High-Performance Liquid Chromatography) to ensure sample purity.</li></ol><p><strong>You can also visit the full range of syringe filters on the </strong><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/?s=syringe+filters&amp;post_type=product&amp;dgwt_wcas=1?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty"><strong>Watrex website</strong></a><strong>.</strong></p>

Watrex VICI Consumables for HPLC/GC

As an authorized distributor of VICI, we provide a wide range of high-quality chromatography consumables that meet the most demanding requirements for precision and reliability.

<p><strong>As an authorized distributor of VICI, we provide a wide range of high-quality chromatography consumables that meet the most demanding requirements for precision and reliability.</strong></p><p>Our offer includes <strong>injection valves, adapters, tubing, filters, columns</strong> and other products that optimize the performance of your HPLC systems. Thanks to our close cooperation with partners, we guarantee the latest technology and expert advice.</p><p>Explore our range using the <strong>catalogs from</strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Watrex_VICI_V_ddafed74a8.pdf"><strong> VICI Valco</strong></a><strong> and </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Watrex_VICI_J_c72f706329.pdf"><strong>VICI Jour</strong></a> and do not hesitate to contact us for a non-binding quote at watrex@watrex.com or visit our website <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/cs/uvod/?utm_source=labrulez">www.watrex.com</a>.</p><h3>VICI Valco Instuments</h3><p>For over 50 years, VICI Valco Instruments Co. Inc. has been the leading designer and manufacturer of standard and custom valves and fittings for precision analytical, biomedical, and biocompatible instrumentation.</p><h4>The offer includes, for example:</h4><ul><li><strong>Injectors and valves</strong></li><li><strong>Fittings</strong></li><li><strong>Detectors</strong></li><li><strong>Valve actuation and accessories</strong></li></ul><p>Vici Valco product line also includes a wide range of related products such as pneumatic and electric actuators, tubing and sampling loops, heated enclosures, valve sequence and temperature controllers, gas purifiers, GC detectors, and digital interfaces.</p><h3>VICI Jour</h3><p>VICI Jour offer the complete Jour line of accessories and consumables for fluid transfer in HPLC and LC.</p><h4>The offer includes, for example:</h4><ul><li><strong>Tubing (PEEK, F-polymeric, stainless steel)</strong></li><li><strong>Fittings (high pressure and low pressure)</strong></li><li><strong>Filters (high pressure and low pressure) and frits</strong></li><li><strong>Safety products</strong></li><li><strong>PEEK columns and guard columns</strong></li><li><strong>Tools and LC accessories</strong></li></ul><p>Jour products include a complete line of tubing and capillaries in a wide variety of diameters and materials, high and low pressure fingertight fittings and connection accessories, column hardware, high and low pressure filters, cutters and other tools, solvent saver, safey caps, waste caps, backpressure regulators, and much more.</p>

Phenomenex Zebron PLUS GC Inlet Liners

GC liners Zebron PLUS with unique deactivation ensure high inertness for trace and active compound analysis.

<p class="cke-user_style-important"><strong>Protect and Increase the Lifetime of Your GC Column</strong></p><h4><strong>Why Use Pre-Packed Liners?</strong></h4><p>Though the upfront cost of self-packing your liner may seem attractive, the time and headaches caused by resulting tailing or irreproducible peaks can be sizeable! Self-packed wool fibers commonly break during installation and any existing deactivation on the liner can also be scratched or damaged. Pre-packed Zebron PLUS liners undergo the deactivation process with the quartz wool already in place, which ensures that any active sites that form during packing are not exposed.</p><h4><strong>Deactivation Protects Your Samples</strong></h4><h5><strong>See the difference: Zebron PLUS vs. Traditional Deactivation</strong></h5><p>Zebron PLUS GC inlet liners undergo a unique deactivation process, resulting in a remarkably inert pathway that prevents sample adsorption and degradation for active compounds.</p><p><strong>A: Zebron PLUS Deactivation</strong></p><p>Every batch of Zebron PLUS liners is manufactured with a thick layer of vapor-deposited deactivation for the highest inertness. They are then tested for activity using both EPA Methods 8081 and 8270 to ensure the highest level of sample protection possible.</p><p><strong>B: Traditional Deactivation</strong></p><p>Traditionally, liners have only been passivated with thin deactivation layers – and sometimes have not at all – putting your analytes at risk of adsorption or degradation!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_vs_Traditional_Deactivation_5c8ce20af6.jpg" alt="Phenomenex: Zebron PLUS vs. Traditional Deactivation" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_vs_Traditional_Deactivation_5c8ce20af6.jpg 245w," sizes="100vw" width="909" height="567"><br>&nbsp;</p><h4><strong>Easy, Touch free Installation</strong></h4><ul><li>Remarkably inert GC inlet liners for superior sample protection</li><li>Easy to install, touchless packaging allows you to protect yourself from cuts or breakage</li><li>Eliminates contamination that may occur during the installation process</li></ul><p><strong>A: Pre-installed o-ring saves steps</strong></p><p><strong>B: Touchless installation prevents contamination</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Easy_Touch_free_Installation_of_Zebron_GC_Inlet_Liner_dd54ebc577.jpg" alt="Phenomenex: Easy, Touch free Installation of Zebron GC Inlet Liner" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Easy_Touch_free_Installation_of_Zebron_GC_Inlet_Liner_dd54ebc577.jpg 245w," sizes="100vw" width="907" height="573"></p><h4><strong>Liner Geometry Improves Performance</strong></h4><p>The geometry of a liner refers to the type and shape of a liner. Each geometry addresses a particular sample or injection type. use the chart below to determine the best geometry for your sample.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Liner_Geometry_Improves_Performance_9bd57c3c81.jpg" alt="Phenomenex: Liner Geometry Improves Performance" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Liner_Geometry_Improves_Performance_9bd57c3c81.jpg 245w," sizes="100vw" width="1391" height="362"></p><h3><strong>Choose Your Liner</strong></h3><h4><strong data-start="74" data-end="123">For Agilent® or Thermo Scientific® GC Systems</strong></h4><ul><li><strong>Direct Connect</strong> - Trace analysis, Splitless injections (4 x 78.5 mm) &nbsp;<ul><li>Part Nos: AG2-0A50-01, AG2-0A50-05, AG2-0A50-25 &nbsp;</li></ul></li><li><strong>Single Taper</strong> - Pesticides (4 x 78.5 mm) &nbsp;<ul><li>Part Nos: AG2-0A10-01, AG2-0A10-05, AG2-0A10-25 &nbsp;</li></ul></li><li><strong>Single Taper Z-Liner™</strong> - Semi-volatiles, Dirty samples (4 x 78.5 mm) &nbsp;<ul><li>Part Nos: AG2-0A13-01, AG2-0A13-05, AG2-0A13-25 &nbsp;</li></ul></li><li><strong>Single Taper with Wool</strong> - Semi-volatiles (4 x 78.5 mm) &nbsp;<ul><li>Part Nos: AG2-0A11-01, AG2-0A11-05, AG2-0A11-25 &nbsp;</li></ul></li><li><strong>Straight</strong> - Volatiles (4 x 78.5 mm) &nbsp;<ul><li>Part Nos: AG2-0A00-01, AG2-0A00-05, AG2-0A00-25 &nbsp;</li></ul></li><li><strong>Straight Z-Liner™</strong> - Dirty samples, Volatiles, High initial oven temperatures (4 x 78.5 mm) &nbsp;<ul><li>Part Nos: AG2-0A03-01, AG2-0A03-05, AG2-0A03-25 &nbsp;</li></ul></li><li><strong>Straight Single Baffle</strong> - Semi-volatiles, Pesticides (1.8 x 71 mm) &nbsp;<ul><li>Part Nos: AG2-1F06-01, AG2-1F06-05, AG2-1F06-25 &nbsp;</li></ul></li></ul><h4><strong>For PerkinElmer® GC Systems</strong></h4><ul><li><strong>Single Taper </strong>- Pesticides (4 x 92 mm) &nbsp;<ul><li>Part Nos: AG2-2A10-01, AG2-2A10-05, AG2-2A10-25 &nbsp;</li></ul></li><li><strong>Single Taper Z-Liner™</strong> - Semi-volatiles, Dirty samples (4 x 92 mm) &nbsp;<ul><li>Part Nos: AG2-2A13-01, AG2-2A13-05, AG2-2A13-25 &nbsp;</li></ul></li><li><strong>Straight</strong> - Volatiles (4 x 92 mm) &nbsp;<ul><li>Part Nos: AG2-2A00-01, AG2-2A00-05, AG2-2A00-25 &nbsp;</li></ul></li><li><strong>Straight Z-Liner™</strong> - Volatiles, Dirty samples (2 x 86.2 mm) &nbsp;<ul><li>Part Nos: AG2-2E03-01, AG2-2E03-05, AG2-2E03-25 &nbsp;</li></ul></li><li><strong>Straight Z-Liner™</strong> - High initial oven temperatures (4 x 92 mm) &nbsp;<ul><li>Part Nos: AG2-2A03-01, AG2-2A03-05, AG2-2A03-25 &nbsp;</li></ul></li></ul><h4><strong>For Shimadzu® GC Systems</strong></h4><h5><strong>Shimadzu 17A GC Systems</strong></h5><ul><li><strong>Single Taper Z-Liner™</strong> - Pesticides (3.4 x 95 mm) &nbsp;<ul><li>Part Nos: AG2-3B13-01, AG2-3B13-05, AG2-3B13-25 &nbsp;</li></ul></li><li><strong>Straight Z-Liner™</strong> - Volatiles, Dirty samples, High initial oven temperatures (3.4 x 95 mm) &nbsp;<ul><li>Part Nos: AG2-3B03-01, AG2-3B03-05, AG2-3B03-25 &nbsp;</li></ul></li></ul><h5><strong>Shimadzu 2010 GC Systems&nbsp;</strong></h5><ul><li><strong>Single Taper</strong> - Pesticides (3.4 x 95 mm) &nbsp;<ul><li>Part Nos: AG2-4B10-01, AG2-4B10-05, AG2-4B10-25 &nbsp;</li></ul></li><li><strong>Single Taper Z-Liner™</strong> - Semi-volatiles, Dirty samples (3.4 x 95 mm) &nbsp;<ul><li>Part Nos: AG2-4B13-01, AG2-4B13-05, AG2-4B13-25 &nbsp;</li></ul></li><li><strong>Straight</strong> - Volatiles (3.4 x 95 mm) &nbsp;<ul><li>Part Nos: AG2-4B00-01, AG2-4B00-05, AG2-4B00-25 &nbsp;</li></ul></li><li><strong>Straight Z-Liner™</strong> - Volatiles, Dirty samples, High initial oven temperatures (3.4 x 95 mm) &nbsp;<ul><li>Part Nos: AG2-4B03-01, AG2-4B03-05, AG2-4B03-25 &nbsp;</li></ul></li></ul>

Phenomenex Strata C18-E Solid Phase Extraction (SPE)

Strata C18-E is a silica-based end-capped C18 solid phase extraction (SPE) sorbent.

<p><strong>Strong Hydrophobic Retention Solid Phase Extraction (SPE)</strong></p><p>Strata C18-E is a <strong>silica-based</strong> <strong>end-capped C18</strong> solid phase extraction (SPE) sorbent that offers <strong>strong hydrophobic retention</strong> with negligible secondary polar interactions from active silanol groups. Strata C18-E can be best used for the <strong>extraction of hydrophobic</strong> or <strong>polar organic analytes</strong> from <strong>aqueous matrices</strong>. In addition, Strata SPE sorbents are manufactured with the highest purity and extensively tested to give clean extracts.</p><p>Strata C18-E is <strong>compatible</strong> with various formats, including <strong>C18 SPE cartridges</strong>. Our C18 SPE products are synonymous with quality, offering the highest purity and undergo rigorous testing to deliver consistently clean extracts for your analytical needs.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_C18_E_748c192b52.webp" alt="Phenomenex: Strata-C18-E" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_C18_E_748c192b52.webp 245w," sizes="100vw" width="500" height="150"></p><ul><li><strong>Surface Area (m²/g)</strong>: 500, m²/g</li><li><strong>Separation Mode:</strong> Reversed Phase</li><li><strong>Pore Size:</strong> 70, 100</li><li><strong>Particle Size:</strong> 20, 55</li><li><strong>Recommended Use: </strong>Extraction of hydrophobic molecules</li></ul><h4><strong>Starting Method</strong></h4><h5><strong>Strata Reversed Phase</strong></h5><ul><li><strong>Condition:</strong> 1 mL Methanol</li><li><strong>Equilibrate:</strong> 1 mL DI Water</li><li><strong>Load:</strong> Pretreated sample</li><li><strong>Wash</strong>: 1 mL 5% Methanol in DI Water, dry under vacuum for 2-5 min</li><li><strong>Elute:</strong> 1 mL Methanol</li></ul><p>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.</p>

Phenomenex Zebron ZB-1plus GC Columns

Zebron ZB-1plus is a very low bleed (MS Certified) phase especially suited to high sensitivity GC-MS

<h4><strong>MS Certified “1” Phase</strong></h4><ul><li><strong>Very low bleed</strong> (MS Certified) phase especially suited to high sensitivity GC-MS</li><li><strong>Extremely inert</strong> for active compounds such as drugs, pesticides, or acids and bases</li><li><strong>Improved signal-to-noise ratio</strong> for better sensitivity and mass spectral integrity</li><li>Equivalent selectivity to <strong>100 % dimethylpolysiloxane phases</strong></li></ul><p><strong>We tested the ZB-1PLUS column bleed profile against other “MS” columns on the market – ZB-1PLUS shows the lowest bleed, even at temperatures up to 360 °C.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1plus_Lower_Column_Bleed_e761722aea.jpg" alt="Phenomenex: Zebron ZB-1plus - Lower Column Bleed" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1plus_Lower_Column_Bleed_e761722aea.jpg 213w," sizes="100vw" width="1000" height="733"></p><h4><strong>Recommended Use</strong></h4><ul><li>Especially suited to high sensitivity GC-MS and extremely inert for active compounds</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Acids</li><li>Amines</li><li>Drugs</li><li>EPA Methods (1668)</li><li>Diesel Fuel</li><li>Essential Oils</li><li>Flavors &amp; Fragrances</li><li>Oxygenates and GROs</li><li>PCBs</li><li>Pesticides</li><li>Solvent Impurities</li><li>Sulfur Compounds (Light)</li></ul><h5><strong>Upgrade to ZB-1<sub>PLUS</sub> from any 100 % dimethylpolysiloxane phase:</strong></h5><p><strong>Agilent®</strong></p><ul><li>DB®-1</li><li>DB-1ms</li><li>DB-1ms Ultra Inert</li><li>HP-1</li><li>HP-1ms</li><li>HP-1ms Ultra Inert</li><li>VF-1ms</li><li>CP-Sil 5 CB</li><li>Ultra 1</li></ul><p><strong>Restek®</strong></p><ul><li>Rtx®-1</li><li>Rtx-1ms</li><li>Rxi®-1ms</li></ul><p><strong>SGE®</strong></p><ul><li>BP1</li><li>SolGel-1ms™</li></ul><p><strong>Supelco®</strong></p><ul><li>PB®-1</li><li>SE-30</li><li>MET-1</li><li>MDN-1</li><li>Equity®-1</li></ul><h3><strong>Phenomenex Zebron PLUS GC Columns</strong></h3><h4><strong>What’s in the Zebron™ PLUS?</strong></h4><ul><li>Active sites on a GC column’s surface can result in analyte adsorption and degradation, which negatively affect peak shape and response.</li><li>To reduce potential surface activity, <strong>Zebron PLUS phases</strong> (ZB-1plus, ZB-5plus, ZB-5MSplus, and ZB-624plus) are designed with a rigorous fused silica deactivation process that improves inertness and peak shapes for troublesome compounds</li><li>Zebron ZB-WAX<sub>PLUS</sub> is specially designed for <strong>100% aqueous stability</strong>, <strong>enhanced resolution</strong> and <strong>better reproducibility</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg" alt="Phenomenex: Zebron PLUS GC Column phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg 245w," sizes="100vw" width="1191" height="454"></p>

Phenomenex Zebron ZB-5MSplus GC Columns

Zebron ZB-5MSplus is a low bleed (MS Certified) and well-suited to high sensitivity GC-MS and GC-MS/MS work

<h4><strong>The Next Generation of Inertness</strong></h4><ul><li>The next generation of inertness for specialty chemical, forensic, toxicology, and food testing applications</li><li>Specialized deactivation for versatile 5 % phenylarylene selectivity with improved sensitivity</li><li>Low bleed (MS Certified) and well-suited to high sensitivity GC-MS and GC-MS/MS work</li></ul><h4><strong>Engineered for High Performance</strong></h4><h5><strong>Improved Inertness, Better Peak Shape, Low Bleed, and Aqueous Stability</strong></h5><p>Active sites on a GC column’s surface can result in analyte adsorption and degradation, negatively affecting peak shape and response. To reduce potential surface activity, Zebron ZB-5MSplus is designed with a <strong>rigorous fused silica deactivation process </strong>that improves inertness for troublesome compounds. Instantly achieve higher responses for active compounds compared to your current 5ms phase column, without changing your selectivity.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_5_M_Splus_Improved_Inertness_Better_Peak_Shape_Low_Bleed_and_Aqueous_Stability_e424743162.jpg" alt="Phenomenex: Zebron ZB-5MSplus - Improved Inertness, Better Peak Shape, Low Bleed, and Aqueous Stability" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_5_M_Splus_Improved_Inertness_Better_Peak_Shape_Low_Bleed_and_Aqueous_Stability_e424743162.jpg 157w," sizes="100vw" width="905" height="901"></p><h5><strong>Better peak shape</strong></h5><figure class="image"><img style="aspect-ratio:1243/592;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_5_MS_Plus_vs_other_5_MS_Columns_e7a202e862.jpg" alt="Phenomenex: Zebron ZB-5MS Plus vs other 5MS Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_5_MS_Plus_vs_other_5_MS_Columns_e7a202e862.jpg 245w," sizes="100vw" width="1243" height="592"></figure><h4><strong>Recommended Use</strong></h4><ul><li>Specialized deactivation for versatile 5% Phenyl-Arylene selectivity with improved sensitivity</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Acids</li><li>Alkaloids</li><li>Amines</li><li>Drugs</li><li>Essential Oils</li><li>Flavors</li><li>Halo-hydrocarbons</li><li>Pesticides</li><li>Phenols</li><li>Residual Solvents</li><li>Solvent Impurities</li></ul><h5><strong>Upgrade to ZB-5MS<sub>PLUS</sub> from any 5 % phenyl or 5 % phenyl-arylene / 95 % dimethylpolysiloxane phase:</strong></h5><h5><strong>Agilent®</strong></h5><ul><li>DB®-5ms</li><li>DB-5ms Ultra Inert</li><li>HP-5ms</li><li>HP-5ms Ultra Inert</li><li>VF-5ms</li></ul><h5><strong>Restek®</strong></h5><ul><li>Rxi®-5Sil MS</li></ul><h5><strong>Supelco®</strong></h5><ul><li>SLB®-5ms</li></ul><h3><strong>Phenomenex Zebron PLUS GC Columns</strong></h3><h4><strong>What’s in the Zebron™ PLUS?</strong></h4><ul><li>Active sites on a GC column’s surface can result in analyte adsorption and degradation, which negatively affect peak shape and response.</li><li>To reduce potential surface activity, <strong>Zebron PLUS phases</strong> (ZB-1plus, ZB-5plus, ZB-5MSplus, and ZB-624plus) are designed with a rigorous fused silica deactivation process that improves inertness and peak shapes for troublesome compounds</li><li>Zebron ZB-WAX<sub>PLUS</sub> is specially designed for <strong>100% aqueous stability</strong>, <strong>enhanced resolution</strong> and <strong>better reproducibility</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg" alt="Phenomenex: Zebron PLUS GC Column phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg 245w," sizes="100vw" width="1191" height="454"></p>

Phenomenex Zebron ZB-5plus GC Columns

Zebron ZB-5plus is Highly inert - improved peak shape for acidic/basic compounds, drugs of abuse, and pesticides

<h4><strong>Inert, Low Bleed 5% Phenyl Selectivity</strong></h4><ul><li>Highly inert - improved peak shape for acidic/basic compounds, drugs of abuse, and pesticides</li><li>Very low bleed (MS certified) levels provide maximum sensitivity</li><li>Intense QC specifications ensure column-to-column performance</li><li>Engineered Self Cross-linking™ (ESC) bonding results in phase stability and high temperature limits</li><li>Same selectivity as the 5 % phenyl / 95 % dimethylpolysiloxane phase</li></ul><h4><strong>Recommended Use</strong></h4><ul><li>Highly inert for improved peak shape of acidic/basic compounds, drugs of abuse, and pesticides</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Barbiturates</li><li>Benzodiazepines</li><li>Drugs of Abuse</li><li>EPA Methods</li><li>FAMEs</li><li>Nitrosamines</li><li>Pesticides</li><li>Phenols</li><li>THC Metabolites</li></ul><h5><strong>Upgrade to ZB-5<sub>PLUS</sub> from any 5 % phenyl / 95 % dimethylpolysiloxane phase:</strong></h5><p><strong>Agilent®</strong></p><ul><li>DB®-5</li><li>HP-5</li><li>HP-5ms</li><li>HP-5msi</li></ul><p><strong>Restek®</strong></p><ul><li>Rtx®-5</li><li>Rtx-5MS</li><li>Rtx-5Amine</li><li>Rxi®-5ms</li></ul><p><strong>SGE®</strong></p><ul><li>BP5</li><li>BPX5</li></ul><p><strong>Supelco®</strong></p><ul><li>MDN-5S</li><li>SPB®-5</li><li>Equity®-5</li></ul><p><strong>OV®</strong></p><ul><li>OV-5</li></ul><h3><strong>Phenomenex Zebron PLUS GC Columns</strong></h3><h4><strong>What’s in the Zebron™ PLUS?</strong></h4><ul><li>Active sites on a GC column’s surface can result in analyte adsorption and degradation, which negatively affect peak shape and response.</li><li>To reduce potential surface activity, <strong>Zebron PLUS phases</strong> (ZB-1plus, ZB-5plus, ZB-5MSplus, and ZB-624plus) are designed with a rigorous fused silica deactivation process that improves inertness and peak shapes for troublesome compounds</li><li>Zebron ZB-WAX<sub>PLUS</sub> is specially designed for <strong>100% aqueous stability</strong>, <strong>enhanced resolution</strong> and <strong>better reproducibility</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg" alt="Phenomenex: Zebron PLUS GC Column phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg 245w," sizes="100vw" width="1191" height="454"></p>

Phenomenex Zebron ZB-624plus GC Columns

Zebron ZB-624PLUS is the optimal choice for the analysis of volatile compounds for Environmental, Pharmaceutical, Food, Cannabis, and Specialty Chemicals.

<h4><strong>The Next Generation of GC Inertness</strong></h4><p>Zebron ZB-624PLUS is the optimal choice for the analysis of <strong>volatile compounds</strong> for <strong>Environmental</strong>, <strong>Pharmaceutical,</strong> <strong>Food</strong>, <strong>Cannabis</strong>, and <strong>Specialty Chemicals</strong>. The superior “Plus” deactivation process enhances peak shape, improves signal-to-noise levels and increases sensitivity for qualitative and quantitative analysis of active compounds. Upgrade your existing 624 phase to Zebron ZB-624PLUS GC columns and get all the analytical benefits of proven inertness.</p><ul><li><strong>Enhanced peak shape</strong> with superior deactivation</li><li><strong>Increased sensitivity</strong> for high boiling solvents</li><li><strong>Extremely low bleed</strong> for GC-MS</li><li><strong>High temperature stability</strong> (300/320 ºC)</li></ul><h4><strong>What makes the </strong><i><strong>PLUS</strong></i><strong> in ZB-624<sub>PLUS</sub>?</strong></h4><ul><li><h5><strong>Low Bleed</strong></h5><ul><li>Engineered Self Cross-linking™ (ESC™) provides high thermal stability with maximum column temperatures up to 300/320 °C.</li></ul></li><li><h5><strong>Enhanced Inertness</strong></h5><ul><li>Proprietary superior deactivation gives great peak shape for troublesome compounds.</li></ul></li><li><h5><strong>High Selectivity</strong></h5><ul><li>A G43 phase that’s highly selective for polar, non-polar, low and high boiling solvents.</li></ul></li><li><h5><strong>Column-to-Column Reproducibility</strong></h5><ul><li>Excellent column-to-column reproducibility well suited for validated methods.</li></ul></li><li><h5><strong>Temperature Limits</strong></h5><ul><li>Push the temperature limits of traditional 624 and elute/ bake high boiling analytes at 300/320 °C.</li></ul></li><li><h5><strong>MS Certified</strong></h5><ul><li>Low bleed characteristics makes it the right choice for GC-MS.</li></ul></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_624plus_Meet_your_Zebron_ZB_624_PLUS_GC_Column_fa4f56ed66.jpg" alt="Phenomenex: Zebron-624plus - Meet your Zebron ZB-624PLUS GC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_624plus_Meet_your_Zebron_ZB_624_PLUS_GC_Column_fa4f56ed66.jpg 245w," sizes="100vw" width="1340" height="778"></p><h4><strong>Low Bleed = Better Signal-to-Noise Ratio = Lower Detection Limits</strong></h4><ul><li>The <strong>low bleed</strong> character of <strong>ZB-624PLUS™</strong> columns is the result of advances in <strong>cross-linking</strong> manufacturing processes that we established for these columns.</li><li>With ZB-624PLUS™, your GC column undergoes proprietary cross-linking process to get extensive <strong>Engineered Self Cross-linkage (ESC™)</strong>.</li></ul><h4><strong>Recommended Use</strong></h4><ul><li>Enhanced peak shape with superior deactivation and increased sensitivity for high boiling solvent, extremely low bleed for GC-MS with high temperature stability (300/320°C)</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Cannabis</li><li>Terpenes</li><li>Residual Solvents</li><li>Volatile Amines</li><li>EPA Method 8260</li><li>EPA Method 524</li><li>EPA Method 624</li><li>Food</li><li>Flavors and Fragrances</li><li>Solvent Purity</li><li>Alcohols</li></ul><h4><strong>Upgrade to Zebron from these similar* phases:</strong></h4><p><strong>Agilent®</strong></p><ul><li>CP-Select 624 CB</li><li>DB-624UI Ultra Inert</li></ul><p><strong>Restek®</strong></p><ul><li>Rxi-624Sil MS</li></ul><p><strong>*not exact equivalent, selectivity may differ</strong></p><h3><strong>Phenomenex Zebron PLUS GC Columns</strong></h3><h4><strong>What’s in the Zebron™ PLUS?</strong></h4><ul><li>Active sites on a GC column’s surface can result in analyte adsorption and degradation, which negatively affect peak shape and response.</li><li>To reduce potential surface activity, <strong>Zebron PLUS phases</strong> (ZB-1plus, ZB-5plus, ZB-5MSplus, and ZB-624plus) are designed with a rigorous fused silica deactivation process that improves inertness and peak shapes for troublesome compounds</li><li>Zebron ZB-WAX<sub>PLUS</sub> is specially designed for <strong>100% aqueous stability</strong>, <strong>enhanced resolution</strong> and <strong>better reproducibility</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg" alt="Phenomenex: Zebron PLUS GC Column phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg 245w," sizes="100vw" width="1191" height="454"></p>

Phenomenex Zebron ZB-WAXplus GC Columns

Zebron ZB-WAXPLUS is 100 % aqueous stable, excellent for aqueous samples

<h4><strong>100% Aqueous Stability for Polar Compounds</strong></h4><h5><strong>Enhanced Aqueous Stability</strong></h5><ul><li>100 % aqueous stable, excellent for aqueous samples</li><li>Extremely inert for acidic compounds</li><li>Enhanced selectivity for low boiling solvents</li><li>High retention of alcohols and chlorinated solvents</li><li>Increased efficiency at 20 °C</li></ul><h5><strong>No Way!</strong></h5><p>A specialized bonding procedure makes ZB-WAXplus columns exceptionally stable to replicate injections of water-based matrices, while maintaining the selectivity that makes them the scientist’s choice for highly polar compounds.</p><h4><strong>WAX columns from different manufacturers are not always created equal!</strong></h4><p>As part of the Zebron PLUS GC column family, ZB-WAXPLUS is manufactured using improved technologies that reflect our attention to detail every aspect of a ZB-WAXPLUS column’s anatomy is meticulously engineered and individually tested for unprecedented performance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_WA_Xplus_WAX_columns_from_different_manufacturers_are_not_always_created_equal_0502f6d8e4.jpg" alt="Phenomenex: ZebronWAXplus - WAX columns from different manufacturers are not always created equal" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_WA_Xplus_WAX_columns_from_different_manufacturers_are_not_always_created_equal_0502f6d8e4.jpg 224w," sizes="100vw" width="1301" height="904"></p><h4><strong>Water Reproducibility of ZB-WAXPLUS</strong></h4><p>Historically, polyethylene glycol (PEG) phases have been unstable with aqueous samples such as beverages or glycols, resulting in poor reproducibility and decreased lifetime. The ZB-WAXplus bonding procedure results in exceptional stability to repeated injections of aqueous matrices.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_WA_Xplus_Reproducibility_and_Stability_Test_e0f47777a3.jpg" alt="Phenomenex: ZebronWAXplus - Reproducibility and Stability Test" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_WA_Xplus_Reproducibility_and_Stability_Test_e0f47777a3.jpg 245w," sizes="100vw" width="1437" height="818"></p><p>ZB-WAXPLUS provides optimal selectivity for many aqueous soluble compounds such as those found in alcoholic beverages or glycol samples. The ZB WAXPLUS bonding process results in exceptional stability to repeated injections of aqueous matrices like whiskey. Multiple or routine water injections will not alter the efficiency or polarity of the phase over time.</p><h4><strong>Recommended Use</strong></h4><ul><li>Enhanced selectivity for low boiling solvents; high retention of alcohols and chlorinated solvents and extremely inert for acidic compounds</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Alcohols</li><li>Aldehydes</li><li>Aromatics</li><li>Essential Oils</li><li>Flavors &amp; Fragrances</li><li>Free Fatty Acids</li><li>Glycols</li><li>OVIs</li><li>Pharmaceuticals</li><li>Solvents / Residual Solvents</li><li>Styrene</li><li>Xylene Isomers</li></ul><h5><strong>Upgrade to Zebron from any 100 % polyethylene glycol phase:</strong></h5><p><strong>Agilent®</strong></p><ul><li>DB®-WAX</li><li>CAM</li><li>HP-20M</li><li>Carbowax 20M</li><li>CP-Wax 52 CB</li></ul><p><strong>Restek®</strong></p><ul><li>Stabilwax®</li></ul><p><strong>SGE®</strong></p><ul><li>BP20</li></ul><p><strong>Supelco®</strong></p><ul><li>SUPELCOWAX®10</li></ul><h3><strong>Phenomenex Zebron PLUS GC Columns</strong></h3><h4><strong>What’s in the Zebron™ PLUS?</strong></h4><ul><li>Active sites on a GC column’s surface can result in analyte adsorption and degradation, which negatively affect peak shape and response.</li><li>To reduce potential surface activity, <strong>Zebron PLUS phases</strong> (ZB-1plus, ZB-5plus, ZB-5MSplus, and ZB-624plus) are designed with a rigorous fused silica deactivation process that improves inertness and peak shapes for troublesome compounds</li><li>Zebron ZB-WAX<sub>PLUS</sub> is specially designed for <strong>100% aqueous stability</strong>, <strong>enhanced resolution</strong> and <strong>better reproducibility</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg" alt="Phenomenex: Zebron PLUS GC Column phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg 245w," sizes="100vw" width="1191" height="454"></p>

Thermo Scientific QuEChERS Sample Preparation Kits

QuEChERS is a versatile sample preparation method for analyzing pesticides, veterinary drugs, and other residues in various sample types before GC-MS or LC-MS analysis.

<div><div><div><h3><strong>QuEChERS sample preparation—now easier, more convenient, and affordable</strong></h3><p><strong>QuEChERS</strong> (<strong><u>Q</u></strong><u>u</u>ick, <strong><u>E</u></strong>asy, <strong><u>C</u></strong>heap, <strong><u>E</u></strong>ffective, <strong><u>R</u></strong>ugged, and <strong><u>S</u></strong>afe)is a <strong>sample preparation method</strong> that was initially developed in 2003 for <strong>analyzing veterinary drugs in food</strong>. The method was also tested for <strong>pesticide residue analysis in plant material</strong> with great success. In 2003, the <strong>detailed method was published</strong> in the journal AOAC International. Since then, the QuEChERS method has evolved into a <strong>sample preparation technique used on a variety of analytes</strong> in an <strong>expanding number of sample types</strong> before analysis by <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/cz/en/home/industrial/mass-spectrometry/gas-chromatography-mass-spectrometry-gc-ms.html"><strong>GC-MS</strong></a><strong> or </strong><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/cz/en/home/industrial/mass-spectrometry/liquid-chromatography-mass-spectrometry-lc-ms.html"><strong>LC-MS</strong></a>.</p><p><strong>Thermo Scientific QuEChERS kits</strong> contain <strong>pre-packaged, ready-weighed salts, sorbents, and buffers</strong> to <strong>streamline your workflow</strong> and <strong>minimize the potential for error</strong>. The kits are grouped according to your <strong>analytes of interest</strong>, <strong>sample matrix</strong>, and <strong>preferred QuEChERS method</strong>:</p><ul><li><strong>Original 2003 Method</strong></li><li><strong>AOAC 2007.01 Method</strong></li><li><strong>EN 15662 Method</strong></li><li><strong>NY/T 1380-2007 Method</strong></li></ul><p><strong>Complete packages</strong>—including both <strong>extraction and clean-up kits</strong>—are available. <strong>Extraction-only and cleanup-only kits</strong> are also offered to suit your laboratory’s sample preparation needs. These <strong>pre-packaged kits save time and money</strong>, make QuEChERS procedures <strong>easier and more convenient</strong>, and ensure <strong>quality to yield reproducible results</strong> and <strong>excellent recoveries</strong> for a wide variety of analytes.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Qu_E_Ch_ERS_Sample_Preparation_Kits_2_1e99f0c81b.jpg" alt="Thermo Scientific QuEChERS Sample Preparation Kits" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Qu_E_Ch_ERS_Sample_Preparation_Kits_2_1e99f0c81b.jpg 217w," sizes="100vw" width="891" height="640"></p><h3><strong>Typical QuEChERS workflow</strong></h3><div><div><div><div><div><p>As shown in the workflow diagram below, the <strong>QuEChERS method has four basic steps</strong>:</p><ol><li><strong>Homogenize sample</strong> (fruit or vegetable)</li><li><strong>Extract analytes of interest</strong> from a sample using <strong>extraction salts</strong> (pesticide residues, veterinary drugs, and/or mycotoxins)</li><li><strong>Clean-up the resulting supernatant</strong> using <strong>dispersive solid phase extraction (dSPE)</strong></li><li><strong>Analyze by GC-MS or LC-MS</strong></li></ol><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Qu_E_Ch_ERS_Sample_Preparation_Kits_496491ceff.jpeg" alt="Thermo Scientific QuEChERS Sample Preparation Kits" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Qu_E_Ch_ERS_Sample_Preparation_Kits_496491ceff.jpeg 245w," sizes="100vw" width="1170" height="706"></p><div><h3><strong>QuEChERS products</strong></h3></div><div><h4><strong>QuEChERS extraction kits for original 2003 method</strong></h4></div><div><p>The <strong>original QuEChERS method</strong> (Anastassiades et al, 2003) was developed by <strong>Steven J. Lehotay and Michelangelo Anastassiades</strong> in 2003 for the <strong>determination of pesticide residues in fruits and vegetables</strong>. The original method was created to <strong>analyze non-base-sensitive compounds</strong> and uses a <strong>sodium chloride buffer</strong> to <strong>reduce polar interferences</strong> and <strong>enhance extraction</strong>. <strong>Buffering</strong> is an important part of the QuEChERS procedure because it <strong>allows for analysis of pesticides and other residues</strong> that display <strong>pH dependence in their recoveries</strong>, depending on the <strong>sample matrix</strong>. <strong>Three different extraction kits</strong> are available to support the <strong>original 2003 QuEChERS method</strong>.</p><h5><strong>Chemicals used in the original 2003 method</strong></h5></div><ul><li><strong>Acetonitrile:</strong> Used to perform single-phase extraction (SPE) on a sample</li><li><strong>Anhydrous MgSO₄:</strong> Induces phase separation between water content in sample and acetonitrile layer during liquid-liquid partitioning step; removes remaining water from sample during dispersive solid phase extraction (dSPE) step</li><li><strong>NaCl:</strong> Induces phase separation between water content in sample and acetonitrile layer during liquid-liquid partitioning step; removes residual water from sample; reduces polar interference and enhances extraction</li><li><strong>PSA:</strong> Primary secondary amine, used to remove polar matrix components, citric co-extractives, and free fatty acids, from sample during dispersive solid phase extraction (dSPE) step</li></ul><div><h4><strong>QuEChERS extraction and clean-up kits for AOAC 2007.01 method</strong></h4><p>The <strong>AOAC 2007.01 QuEChERS Method</strong> was developed by <strong>Steven J. Lehotay and his co-workers</strong>, who <strong>modified the original 2003 method</strong> to accommodate the use of <strong>acetate buffering at higher concentration</strong> for <strong>greater buffering strength</strong>. <strong>Buffering</strong> is an important part of the QuEChERS procedure because it <strong>allows for analysis of pesticides and other residues</strong> that display <strong>pH dependence in their recoveries</strong>, depending on the <strong>sample matrix</strong>. These <strong>extraction and clean-up products</strong> here support the <strong>AOAC 2007.01 method</strong>.</p><div><h5><strong>Chemicals used in the AOAC 2007.01 method</strong></h5><ul><li><strong>Acetonitrile:</strong> Used to perform single-phase extraction on a sample</li><li><strong>Anhydrous MgSO₄:</strong> Induces phase separation between water content in sample and acetonitrile layer during liquid-liquid partitioning step; removes remaining water from sample during dispersive solid phase extraction (dSPE) step</li><li><strong>NaOAc:</strong> Buffers the sample to stabilize pH</li><li><strong>PSA:</strong> Primary secondary amine, used to remove polar matrix components, citric co-extractives, and free fatty acids, from sample during dispersive solid phase extraction (dSPE) step</li><li><strong>C18:</strong> Removes fats, sterols, and other non-polar interferences from sample</li><li><strong>GCB:</strong> Graphitized carbon black, removes pigment (<i>not recommended for use with planar pesticides</i>)</li></ul><div><h4><strong>QuEChERS extraction and clean-up kits for EN 15662 method</strong></h4><p>The <strong>extraction and clean-up products</strong> here support the <strong>EN 15662 method</strong>. <strong>Widely used in Europe</strong>, the EN 15662 method was developed by <strong>Michelangelo Anastassiades and co-workers</strong>, who <strong>modified the original 2003 method</strong> to accommodate the use of <strong>citrate buffering at a relatively low buffering capacity</strong>. This variation uses a <strong>sodium chloride buffer</strong> to <strong>minimize polar interferences</strong> in addition to <strong>sodium citrate dihydrate</strong> and <strong>disodium citrate sesquihydrate buffers</strong>. <strong>Buffering</strong> is an important part of the QuEChERS procedure because it <strong>allows for analysis of pesticides and other residues</strong> that display <strong>pH dependence in their recoveries</strong>, depending on the <strong>sample matrix</strong>.</p><h5><strong>Chemicals used in the EN 15662 method</strong></h5><ul><li><strong>Acetonitrile:</strong> Used to perform single-phase extraction on a sample</li><li><strong>Anhydrous MgSO₄:</strong> Induces phase separation between water content in sample and acetonitrile layer during liquid-liquid partitioning step; removes remaining water from sample during dispersive solid phase extraction (dSPE) step</li><li><strong>NaCl:</strong> Induces phase separation between water content in sample and acetonitrile layer during liquid-liquid partitioning step; removes residual water from sample</li><li><strong>Trisodium Citrate:</strong> Buffers the sample to stabilize pH</li><li><strong>Disodium Citrate Sesquihydrate:</strong> Buffers the sample to stabilize pH</li><li><strong>PSA:</strong> Primary secondary amine, used to remove polar matrix components, citric co-extractives, and free fatty acids, from sample during dispersive solid phase extraction (dSPE) step</li><li><strong>C18:</strong> Removes fats, sterols, and other non-polar interferences from sample</li><li><strong>GCB:</strong> Graphitized carbon black, removes pigment (<i>not recommended for use with planar pesticides</i>)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Qu_E_Ch_ERS_Sample_Preparation_Kits_3_721562526f.jpg" alt="Thermo Scientific QuEChERS Sample Preparation Kits" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Qu_E_Ch_ERS_Sample_Preparation_Kits_3_721562526f.jpg 245w," sizes="100vw" width="1471" height="488"></p><div><h4><strong>QuEChERS clean-up kit for NY/T 1380-2007 method</strong></h4></div><div><p>The <strong>NY/T 1380-2007 method</strong> is <strong>recommended by China Ministry of Agriculture</strong> for the <strong>QuEChERS Method sample preparation</strong> of <strong>51 specific pesticide residues</strong> in <strong>fruits and vegetables</strong> with <strong>analysis by GC-MS</strong>.</p><h5><strong>Chemicals used in the NY/T 1380-2007 method</strong></h5><ul><li><strong>Anhydrous MgSO₄:</strong> Induces phase separation between water content in sample and acetonitrile layer during liquid-liquid partitioning step; removes remaining water from sample during dispersive solid phase extraction (dSPE) step</li><li><strong>PSA:</strong> Primary secondary amine, used to remove polar matrix components, citric co-extractives, and free fatty acids, from sample during dSPE step</li><li><strong>C18:</strong> Removes fats, sterols, and other non-polar interferences from sample</li></ul></div></div></div></div></div></div></div></div></div></div></div></div>

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