🎤 Presenter: Christopher Freye (Los Alamos National Laboratory)💾 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_1_Freye_10783a9cf3.pdf">PDF presentation</a><h3>Abstract</h3>Two-dimensional gas chromatography (<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=2">GC×GC</a>) when coupled with mass spectrometry (MS) especially high-resolution mass spectrometry (HRMS) provides the ideal technique to discover minute chemical changes. However, GC×GC analyses result in extremely large datasets (GBs of information) wherein the statistically significant chemical changes are buried within the background chemical matrix. To combat these issues, many chemometric techniques have been developed or applied. Recently we introduced a new chemometric technique for GC-MS termed alteration analysis (ALA) and two-dimensional correlation (2DCOR) which can be used to discover statistically significant chemical changes across a series of chromatograms and understand the relationship between the statistically relevant changes. ALA generates three sets of information, the basic alteration map (BAM) which is the magnitude of the change, the synchronous alteration map (SAM) which describes the linear change, and the asynchronous alteration map (AAM) which describes the non-linear change. 2DCOR can then be used to understand the relationship between the chemical changes but 2DCOR can also resolve the sequence of the changes. A workflow for GC×GC-MS will be demonstrated. Special attention will be given to what differentiates the GC×GC work flow from GC for both the ALA and 2DCOR.<h3>Video Transcription</h3>The presentation focuses on how advanced mathematical and chemometric methods can be used to extract meaningful information from highly complex chromatographic data, especially in multidimensional chromatography coupled with mass spectrometry (GC×GC-MS, LC-MS).<h4>Why traditional data analysis falls short</h4>Modern multidimensional chromatography generates extremely large datasets, often containing billions of data points. Visual inspection, peak tables, or classical identification-based workflows are impractical—especially when:<ul><li>Samples are highly complex (e.g. petroleum, metabolomics, high explosives)</li><li>Most compounds are unknown unknowns</li><li>The key question is not what the compounds are, but whether samples differ and how</li></ul>Program managers and decision-makers are primarily interested in detecting statistically significant changes, not exhaustive compound identification.<h4>Introduction of Alteration Analysis (ALA)</h4>To address subtle, trend-based changes across series of chromatograms, the speaker introduces Alteration Analysis (ALA), a chemometric approach adapted from spectroscopy and applied to chromatography.ALA quantitatively evaluates how individual data points change across multiple samples, allowing detection of:<ul><li>Extremely subtle trends</li><li>Overlapping peaks</li><li>Changes hidden in noise or baseline interference</li></ul>Key ALA outputs include:<ul><li>BAM (Basic Alteration Map): magnitude of change</li><li>SAM (Systematic Alteration Map): linear changes</li><li>AM (Alteration Map): nonlinear changes</li></ul>Even changes as small as 1% per sample can be detected reliably, including peaks that are heavily overlapped.<h4>Beyond detection: understanding relationships with 2D Correlation</h4>Once statistically significant changes are identified, two-dimensional correlation analysis (2D-COR) is used to understand relationships between changing compounds, including:<ul><li>Whether compounds are correlated or anti-correlated</li><li>The sequence of changes over time (which changes happen first)</li></ul>This is especially critical for degradation and aging studies, where intermediate species may appear and disappear before the final state—information that traditional methods like Fisher ratio or PCA often miss.<h4>Solving GC×GC challenges with tiling</h4>GC×GC data introduces additional challenges due to:<ul><li>Peak misalignment</li><li>Exponential data growth during correlation calculations</li></ul>The presenter explains how tile-based approaches reduce data dimensionality, overcome alignment issues, and make ALA and 2D correlation computationally feasible—even for massive GC×GC-MS datasets.<h4>Real-world application: explosive aging studies</h4>The methodology was applied to aging and decomposition of high explosives, where:<ul><li>Over 250 chemical changes were identified</li><li>Many intermediate species would have been missed using traditional comparisons</li><li>ALA combined with 2D correlation enabled reconstruction of degradation pathways</li><li>The most significant change was not necessarily the first change, a critical insight for risk assessment and stability studies</li></ul><h4>Key takeaway</h4>By combining Alteration Analysis and 2D correlation, the approach:<ul><li>Detects statistically guaranteed chemical changes</li><li>Handles subtle, overlapped, and noisy signals</li><li>Determines magnitude, type, interrelationships, and order of changes</li><li>Shifts chromatographic data analysis from identification-driven to decision-driven</li></ul>This math-driven workflow enables faster, more reliable interpretation of complex chromatographic datasets and provides actionable insights for applications such as explosive aging, pharmaceutical degradation, and complex mixture analysis.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote>

Discovery analysis for GCxGC trends using alteration and 2D correlation (Chris Freye, MDCW 2026)

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 9th February 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring you technical note by Agilent Technologies, presentation by MDCW / University of Copenhagen and application notes by Shimadzu and Thermo Fisher Scientific!<h3>1. Agilent Technologies: What Causes Spots on <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=19&amp;manufacturerItems=1&amp;search=PLOT">PLOT Columns</a>? Will It Affect the Performance of the Column?</h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/te_what_causes_spots_plot_columns_affecting_performance_5994_8775en_agilent_3b7180512a.pdf">Full PDF for download</a></li></ul>Spots on porous layer open tubular (PLOT) columns are caused by small voids in the stationary phase coating inside the tube. These spots are areas where there is an uneven coating or lack of phase. It is normal to find some voids in the phase coating of PLOT columns. The stationary phase in PLOT columns is an opaque, solid, and porous material. In many Agilent PLOT columns such as the GS-Alumina phases, molecular sieves, porous polymers (Q and U), and the GS-OxyPLOT, the stationary phase is visible as a white powder. For many PLOT columns, the stationary phase fill solution is a viscous suspension of particles that are less than 10 microns in diameter. The phase is coated using a dynamic process in which a plug of fill solution is pushed through the tubing, and the plug’s speed and viscosity determines the thickness of the stationary phase layer. Once the PLOT’s stationary phase is deposited, it is held in place by electrostatic charge, chemical interactions between particles, and/or binding agents. In wall‑coated open tubular (WCOT) columns, stationary phases such as polysiloxanes or polyethylene glycols are immobilized by chemical bonding to the glass surface and cross-linking between polymer strands. Because this type of bonding and cross‑linking is not possible with PLOT phases, the result is a stationary phase layer that is both fundamentally different and inherently less stable in PLOT columns than in WCOT&nbsp;columns.<h3>2. MDCW / University of Copenhagen: One-shot tensor decomposition of full-scale GC×GC-VUV datasets for resolving petrochemical groups</h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_17_Schneide_67c8ff7866.pdf">Full PDF for download</a></li></ul>The presentation introduces a novel all-samples-at-once, shift-invariant tri-linear tensor decomposition approach for the analysis of full-scale <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?search=GC%C3%97GC-VUV">GC×GC-VUV</a> datasets, aimed at resolving and quantifying petrochemical groups. Traditional template-based or pixel-based methods struggle with retention-time shifts and co-eluting compounds, often requiring manual intervention and prior chemical knowledge. The proposed approach leverages the intrinsic low-rank structure of GC×GC-VUV data to enable robust, automated group-level analysis across multiple samples simultaneously.At the core of the method is a shift-invariant tri-linear model, conceptually related to PARAFAC and multivariate curve resolution, but extended using frequency-domain (FFT-based) modeling to explicitly account for chromatographic peak shifts. By decomposing the entire dataset in one step, the model provides accurate estimates of peak landscapes, VUV spectra, and relative peak areas, while remaining agnostic to retention-time variability. Importantly, the approach requires only a small number of tunable parameters, making it practical for routine use.The method was demonstrated on a case study involving 14 petrochemical gas-oil samples, including straight-run, hydrotreated, hydroconverted, coker, and light cycle oils. Extracted VUV spectra showed excellent agreement with reference spectra from a VUV spectral database, enabling confident assignment of components to chemical groups such as saturates, olefins, and mono- to poly-aromatics. Quantitative results exhibited high repeatability (RSD typically 3–9%) and strong correlation with established template-based reference methods.Overall, the work demonstrates that one-shot, shift-invariant tensor decomposition provides a powerful and scalable alternative to conventional GC×GC data-analysis strategies. By combining chemical interpretability, robustness to chromatographic shifts, and strong quantitative performance, the approach opens new opportunities for automated, high-confidence group-level analysis of complex petrochemical samples and beyond.<h3>3. Shimadzu: Py-Screener Ver. 3: Simultaneously Test for Substances Regulated Under RoHS, TSCA, and POPs</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00949_en_4754e50164.pdf">Full PDF for download</a></li></ul><h5>User Benefits</h5><ul><li>In just one analysis, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=3&amp;search=Py-Screener">Py-Screener</a> Ver. 3 can determine levels of phthalate esters, brominated flame retardants (PBBs, PBDEs), PIP (3:1), UV-328, dechlorane plus (DP), short-chain chlorinated paraffins (SCCPs), and medium-chain chlorinated paraffins (MCCPs).&nbsp;</li><li>It can also test for SCCPs and MCCPs by electron ionization (EI) instead of negative chemical ionization (NCI).&nbsp;</li><li>PIP (3:1), UV-328, DP, and SCCPs and MCCPs can be screened without the need for corresponding reference materials.</li></ul>Countries and regulatory bodies worldwide are introducing increasingly stringent regulations on the chemical substances used in electronic devices and industrial products. The RoHS Directive and REACH regulations in the EU, the Toxic Substances Control Act (TSCA) in the USA, and the Stockholm Convention on Persistent Organic Pollutants (POPs) are also targeting an increasingly broad range of substances. Therefore, manufacturers are required to accurately identify regulated substances in their products and comply with each regulation. While Py-Screener Ver. 2 can screen for seven phthalate esters and brominated flame retardants, including substances regulated under the RoHS Directive, version 3 can also screen for PIP (3:1), which is regulated under the TSCA, as well as UV328, DP, and SCCPs and MCCPs , which are regulated under the Stockholm Convention on POPs. A list of supported substances isshown in Table 1. This article introduces the simultaneous analysis of multiple regulated substances and a case study of testing specific regulated substances in samples, using Py-Screener Ver. 3.<h4>Analysis Process</h4>Py-Screener Ver. 3 can determine levels of phthalate esters and brominated flame retardants contained in products in accordance with the international analytical standards IEC62321-8 and IEC62321-3-3. It can also test for specific regulated substances (Table 1) under the same conditions and in the same analysis. In this test, background intensity and instrument sensitivity (S/N) were verified before analyzing samples. These parameters are prescribed by IEC62321-8 to ensure the accuracy of the methods used. Background intensity and instrument sensitivity were determined using a reference material (PN: 225-31003- 91) *1 that consisted of a plastic sheet that was spiked with seven phthalate esters. The results met the criteria for both parameters.The testing workflow is shown in Fig. 1. Before testing samples, calibration curves were prepared by analyzing the 1000 mg/kg phthalate ester reference material and polypropylene spiked with brominated flame retardants (ERM-EC591). A hole puncher was used to punch out two discs at a time of the phthalate ester reference material, and a cutter was used to obtain pieces of the other materials. Each material was weighed in a sample cup for analysis. During the analysis of samples, phthalate esters and some of the regulated brominated flame retardants were quantitated using a one-point calibration curve. The remaining brominated flame retardants and specific regulated substances were quantitated using the correction factor database*2 that is included with Py-Screener Ver. 3.<h4>Conclusion</h4>Py-Screener Ver. 3 successfully determined in samples the concentrations of the regulated substances PIP (3:1), UV-328, DP, and SCCPs and MCCPs. Normally, SCCP and MCCP levels are tested using NCI, but Py-Screener Ver. 3 uses EI. This enables it to test for not only SCCPs and MCCPs but also phthalate esters, brominated flame retardants, and other regulated substances in just one analysis. In addition, by using the relative correction factors linked to DEHP in the phthalate ester reference material, the levels of these regulated substances were determined without the need for the corresponding reference materials. Py-Screener Ver. 3 can also create a screening program that addresses substance restrictions under the RoHS Directive, the US TSCA, and the POPs Convention.<h3>4. Thermo Fisher Scientific: Improving low carbon steel production in specialty steel processes</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/prima_pro_process_mass_spectrometer_an1626_7fc840235f.pdf">Full PDF for download</a></li></ul>World crude steel production reached 1,691 million tonnes in 2017, up by 5.3% compared to 2016.1 While much of this capacity is still produced in primary steel processes such as basic oxygen furnaces and electric arc furnaces, the need for refined steel with greater durability and resistance to heat and corrosion has led to the increased use of vacuum degassing processes, such as VOD and RH, in secondary steel production. These processes are able to achieve ultra-low levels of residual carbon, while at the same time retaining desired levels of other alloy materials. If these processes are to achieve the required level of steel product quality, they need fast, continuous gas analysis of the furnace exhaust gas. Without accurate information on the composition of the gas leaving the furnace, any variations in the decarburization process are only detected after the event, resulting in the production of out-of-specification steel.<h4>Advantages of mass spectrometry&nbsp;</h4>Traditional Non-Dispersive Infra-Red (NDIR) analyzers are used in many conventional steelmaking processes to measure CO and CO2 , but they can only sample at atmospheric pressure. In vacuum steelmaking the process pressure changes dramatically, typically from atmospheric pressure down to less than 1 mbar, over the 20-30 minutes of the melt. So NDIR analyzers have to sample some distance downstream from the process. Analytical data is updated several minutes after the gas leaves the melt and the control system is forced to operate on historic rather than real-time data.&nbsp;Paramagnetic analyzers can be used to measure O2 , while thermal conductivity analyzers can be used to measure H2 . These analyzers also suffer from slow response, while the need to operate three different types of analyzers adds to the plant maintenance burden. Moreover, the three analyzers cannot analyze inert gases, so N2 is calculated by difference, a result that suffers from the sum of the errors of the three analytical techniques.&nbsp;Mass spectrometry operates at high vacuum so it is ideal for monitoring vacuum processes. It is also able to monitor all seven components in Table 1 in seconds rather than minutes, ensuring the plant control model is frequently updated with accurate compositional data.<h4>Precision of analysis&nbsp;</h4>At the heart of the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=2&amp;search=Prima+PRO+Mass+Spectrometer">Thermo Scientific™ Prima PRO Mass Spectrometer</a> (MS) is a magnetic sector analyzer which offers unrivalled precision and accuracy compared with other mass spectrometers. Thermo Fisher Scientific manufactures both quadrupole and magnetic sector mass spectrometers; over thirty years of industrial experience have shown the magnetic sector based analyzer offers the best performance for industrial on-line gas analysis.&nbsp;Key advantages of magnetic sector analyzers include improved precision, accuracy, long intervals between calibrations, and resistance to contamination. Typically, analytical precision is between 2 and 10 times better than a quadrupole analyzer, depending on the gases analyzed and complexity of the mixture.&nbsp;A unique feature of the Prima PRO magnet is that it is laminated. Its analysis times are similar to a quadrupole analyzer, offering the unique combination of rapid analysis and high stability. This allows the rapid and extremely stable analysis of an unlimited number of user-defined gases. The scanning magnetic sector is controlled with 24-bit precision using a magnetic flux measuring device for extremely stable mass alignment.&nbsp;The ion source is an enclosed type for high sensitivity, minimum background interference, and maximum contamination resistance. This is a high-energy (1000 eV) analyzer that offers extremely rugged performance in the presence of gases and vapors that have the potential for contaminating the analyzer. Typical performance specifications for the Prima PRO MS are shown in Table 1. Analytical performance is demonstrated by analyzing the calibration bottle over 1 hour following calibration, with an analysis time of just 6 seconds. Standard deviations measured on the calibration cylinder will be equal to or better than the stated values.

News from LabRulezGCMS Library - Week 07, 2026

Although modern agriculture needs to be based on accurate real-time data on soil, plant, and environmental conditions, affordable, sufficiently sensitive, and robust monitoring devices for this purpose are currently missing. According to scientists, low-cost sensors based on new smart materials and printing technologies offer a suitable solution. The results of multidisciplinary research thus far and proposals for the development of these devices have been presented by researchers from Czechia, Great Britain, Spain, and the USA in a review article in the prestigious journal <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1">Nature Communications</a>.“Sensor technologies for monitoring plant health are still in their infancy. Only simple sensors capable of monitoring basic parameters such as pH, soil moisture, or temperature are commonly available on the market. However, if farmers are to face current challenges, including climate change, and ensure sufficient food for humanity, they need much more effective tools that will enable them to monitor, for example, various pathogens, including bacteria and fungi. In our opinion, a suitable solution is a combination of new smart materials and printing for the production of inexpensive, durable, and scalable materials,” said the article’s first author, David Panáček from CATRIN, who worked on the study during his internship at Imperial College London.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152">Sensors for monitoring plant health, for example, lag behind similar devices used in human medicine. According to the authors, advances in materials science, which will enable the development of scalable sensor technologies, play a key role in this potential shift. “Printing techniques, including inkjet printing, screen printing, aerosol printing, 3D printing, and direct laser writing, offer flexible ways to produce flexible sensors, large-area sensors, and sensors integrated directly into plants. The review article summarizes recent advances in printable low-dimensional materials for agricultural sensors, analyzes their physico-chemical properties in relation to sensor performance, and discusses key challenges and future opportunities requiring interdisciplinary integration,” said one of the corresponding authors, Michal Otyepka.The research brought together materials scientists, chemists, biologists, sensing experts, and printing technology specialists. Materials research and the use of graphene-based smart materials were led by scientists from CATRIN at Palacký University and VŠB-Technical University of Ostrava. Plant biologists from CATRIN contributed their knowledge of plant development, their responses to stress conditions, and the monitoring of their properties. Researchers from Imperial College London took care of the electronics, while representatives from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/36"> CEITEC – VUT</a> focused on printing technologies. The team also included leading experts in sensing from the Catalan Institute of Nanoscience and Nanotechnology in Barcelona, and Joseph Wang of the University of California San Diego, the “father of sensing and electrochemistry,” also contributed his extensive knowledge.“This is a groundbreaking study on this topic, which has managed to attract some truly big names in their respective fields. Last but not least, the study demonstrates that interdisciplinarity at CATRIN gives rise to completely new and promising research topics, such as plant sensing and its use for studying plant-environment interactions and smart agriculture,” added another corresponding author, Nuria De Diego.

Current sensors are not good enough. Scientists propose a new way to monitor plant health

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The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.

The Multidimensional Chromatography Workshop

The Czech Advanced Technology and Research Institute (CATRIN) at Palacký University is a cutting-edge scientific hub dedicated to advancing research in the fields of nanotechnology, biotechnology, and biomedicine. At its core, CATRIN boasts outstanding scientific teams, featuring international researchers. We emphasize interdisciplinarity, foster global collaborations, and work to translate our research findings into practical applications.

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Organomation NITRO-GEN Nitrogen Generator

The NITRO-GEN generator was developed with Organomation’s nitrogen evaporators in mind to provide nitrogen generation for sample concentration.

The NITRO-GEN generator was developed with Organomation’s nitrogen evaporators in mind to provide nitrogen generation for sample concentration. The generator is lightweight and easy to set up, requiring only a source of compressed air to run. This unit is an ideal choice for labs with an in-house compressed air source.The generator uses a hollow-fiber membrane to convert compressed air to a stream of 95-99% pure nitrogen gas. The hollow-fiber membrane consists of a series of narrow, semipermeable tubes in a porous membrane. As compressed air travels through the fibers, oxygen and water vapor permeate the membrane and are vented off, leaving a steam of high purity nitrogen gas. At up to 99% purity, the resulting nitrogen gas stream can be used in a variety of sample preparation applications.<h4>NITRO-GEN</h4>The NITRO-GEN produces up to 20 L/min of nitrogen gas and is recommended for evaporation of up to 48 sample positions.&nbsp;<h4>Standard features</h4><ul><li>Adjustable outlet pressure regulator, 0-100 psi</li><li>Dual Stage clean air filtration system</li><li>Requires an oil-less compressed air source</li></ul><h4>Advantages</h4><ul><li>Quick Start-Up Time - Nitrogen is produced instantly, no heat up time</li><li>Saves Energy - No electrical power needed</li><li>Engineered Design - Life expectancy is more than 10 years</li><li>Low Maintenance - Serviceable clean air filter</li><li>Compact and Lightweight - Small footprint conserves valuable bench space</li><li>Reduced CO2 Emissions - No heaters, less energy required</li></ul><h4>Specification</h4><h5>Key Features:</h5><ul><li>Flow Rate: Up to 20 L/min</li><li>Technology: Hollow-fiber membrane</li><li>Output Pressure: Adjustable 0 – 100 PSI</li><li>Electrical Requirements: None (no power required)</li><li>Noise Level: &lt; 40 dBA (virtually silent when connected to an instrument)</li></ul><h5>Inlet Air Requirements:</h5><ul><li>Maximum Inlet Pressure: 150 PSI (10.3 bar)</li><li>Particulate Filtration: ≤ 0.01 µm</li><li>Oil Vapor Content: &lt; 0.01 mg/m³ (&lt; 0.01 ppm)</li><li>Relative Humidity: &lt; 100% (non-condensing)</li><li>Air Quality: Clean, contaminant-free air</li></ul><h5>Environmental Conditions:</h5><ul><li>Operating Temperature: 36–122 °F (2–50 °C)</li><li>Ambient Pressure: Atmospheric</li></ul><h5>Dimensions &amp; Weight:</h5><ul><li>Size (W × D × H): 9.5 × 8 × 19.5 in (241 × 203 × 495 mm)</li><li>Weight: 13.25 lbs (6 kg)</li></ul>Warranty: 1 year

Organomation ROT-X-TRACT-S Soxhlet extractor

Unlike traditional wire or sand baths which are used to heat receiving flasks, the ROT-X-TRACT-S uses a water steam bath which provides gentle even heat to delicate samples.

Soxhlet extraction is ideal for extracting soluble analytes from a solid sample into an organic solvent. Unlike traditional wire or sand baths which are used to heat receiving flasks, the ROT-X-TRACT-S uses a water steam bath which provides gentle even heat to delicate samples.The ROT-X-TRACT-S rotary Soxhlet extractors can accommodate up to 8 or 10 Soxhlet extractors. The bath cover disc holes can accommodate round sample flasks from 125 ml-1 L. Models 13070 and 13090 can accommodate smaller 250 mL flasks, while model 13008 can accommodate larger 500 mL flasks. A wide range of sample sizes and quantities make this instrument ideal for Soxhlet extraction of samples in any lab.<h4>Standard features</h4><ul><li>Stainless steel construction</li><li>Stepped bath rim and cover disk seals steam chamber</li><li>Each condenser water line attached to centrally located water manifold</li><li>Laboratory grade materials stand up to organic solvents</li></ul><h4>OPTIONS (Add to main Cat# when purchasing)</h4><ul><li>Positive pressure type Z purged bath (Option Code -Z), Cat# 13070/13090/13008-Z</li><li>240V wiring and plug (Option Code -2), Cat# 13070/13090/13008-2</li></ul><h4>ACCESSORIES</h4><ul><li>P1332: O-rings for S-EVAP/RXT water manifold</li><li>All associated glassware</li><li>Rotary clamp manifold assembly</li><li>Bath cover disks</li></ul><h4>Specification</h4><h5>Model 13070 – 8 Position, 37 mm Extractors</h5>Ideal for labs using 250 mL round-bottom flasks, this model features a medium-size 12-inch ID water bath (Model 9125) and supports GS3137 or GS3129 glassware.<ul><li>Overall Dimensions: 18 × 16 × 34 in (46 × 41 × 86 cm)</li><li>Heating Power: 900 W</li><li>Temperature Control: Dial thermostat with ±2 °C accuracy</li></ul><h5>Model 13090 – 10 Position, 37 mm Extractors</h5>This high-throughput option also works with 250 mL flasks and uses a larger 16-inch ID bath (Model 16165) to accommodate 10 samples simultaneously.<ul><li>Overall Dimensions: 24 × 19 × 34 in (61 × 48 × 86 cm)</li><li>Heating Power: 1600 W</li><li>Temperature Control: Dial thermostat with ±2 °C accuracy</li></ul><h5>Model 13008 – 8 Position, 50 mm Extractors</h5>For larger sample volumes, Model 13008 supports 500 mL round-bottom flasks and includes a 16-inch bath with higher accuracy temperature control. It uses GS3150 glassware and larger 55/50 extractor joints for robust handling of bigger samples.<ul><li>Overall Dimensions: 24 × 19 × 37 in (61 × 48 × 94 cm)</li><li>Heating Power: 1600 W</li><li>Temperature Control: Dial thermostat with ±0.5 °C accuracy</li></ul><h5>Key Shared Features</h5><ul><li>Extractor Joint Sizes:<ul><li>13070 &amp; 13090: 45/50, 24/40</li><li>13008: 55/50, 24/40</li></ul></li><li>Condenser Options:<ul><li>Standard: Allihn</li><li>Optional: Friedrichs (for enhanced cooling performance)</li></ul></li><li>Condenser Joint Size: 55/50</li><li>Bath Temperature Range: 40–100 °C</li><li>Heating Medium: Water</li><li>Bath Inside Dimensions:<ul><li>13070: 12 × 4.5 in (30.5 × 11.4 cm)</li><li>13090 &amp; 13008: 16 × 4.5 in (40.6 × 11.4 cm)</li></ul></li></ul>

Organomation 12 Position N-EVAP Nitrogen Evaporator

The 12 position N-EVAP nitrogen evaporator is a compact unit that allows for up to 12 samples to be evaporated simultaneously.  At each individual sample position, the gas flow can be controlled via a precision needle valve.

The 12 position N-EVAP nitrogen evaporator (cat# 11155) is a compact unit that allows for up to 12 samples to be evaporated simultaneously. At each individual sample position, the gas flow can be controlled via a precision needle valve. This is ideal for the simultaneous evaporation of samples with varying evaporation end points. The sample tray has a spring tensioner which allows any test tube between 10-30 mm to be processed without any modifications to the instrument. An optional small sample holder allows samples with an outside diameter of 5-16 mm to be processed.First introduced in 1959 as The Meyer N-EVAP, the 12 position N-EVAP (cat# 11155) was the first nitrogen dryer created by Organomation. It has proven to be an extremely durable, time tested and highly affordable member of Organomation’s N-EVAP line. These economical units provide controlled concentration of sample vials through the application of nitrogen gas within a heated water bath. The N-EVAP’s circular rotating design permits each sample to be accessible from the front of the instrument for easy insertion and retrieval. The chrome plated needle valves are individually milled from solid brass, enabling precise, uniform adjustments for your nitrogen blow down. This promotes efficient and safe sample reduction with minimal nitrogen waste.<ul><li>Small Footprint: N-EVAP Model 111 requires under one square foot of bench space</li><li>Flexible: An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li>Customizable: Options are available for use with acidic or flammable solvents, heat- or water-sensitive samples, and more</li><li>Individualized Control: Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_12_Position_N_EVAP_Nitrogen_Evaporator_5_339151fb9f.jpg" alt="Organomation 12 Position N-EVAP Nitrogen Evaporator ." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_12_Position_N_EVAP_Nitrogen_Evaporator_5_339151fb9f.jpg 156w," sizes="100vw" width="1400" height="1400"><h3>STANDARD FEATURES</h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter, 0-10 LPM</li><li>High pressure phthalate free tubing for safety</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly (except in dry bath model)</li><li>Precision needle valve tube assembly</li><li>Needles, 4 inch x 19 gauge with chrome plated brass hub and stainless steel shaft</li></ul><h3>OPTIONS&nbsp;</h3><ul><li>220v wiring harness (Option Code# -2), Cat# 11155-2</li><li>Z-Purge/positive pressure purge case (Option Code# -Z), Cat# 11155-Z</li><li>Acid resistant coating on instrument and needles (Option Code# -RT), Cat# 11155-RT</li></ul><h3>SPECS</h3><h4>12p N-EVAP (Water Bath)</h4><ul><li>Bath Type: Water</li><li>Instrumental Catalog Number: 11155</li><li>Number of Sample Positions: 12</li><li>Overall Dimension (w x d x h): 13 x 11 x 31 in / 33 x 28 x 79 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 5–16 mm OD</li><li>Gas Flow Meter: 0–10 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Optional Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating (Option Code -RT): Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 5585</li><li>Heating Medium: Water</li><li>Inside Dimensions (Diameter × Depth): 8.5 × 4.5 in / 21.6 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 13 × 11 × 7 in / 33 × 28 × 18 cm</li><li>Total Wattage: 550 W</li><li>Bath Temperature Range: 30–90 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ± 2 °C</li></ul><h4>12p N-EVAP (Dry Bath)</h4><ul><li>Bath Type: Dry</li><li>Instrumental Catalog Number: 11155-DA</li><li>Number of Sample Positions: 12</li><li>Overall Dimension (w x d x h): 13 x 11 x 27.5 in / 33 x 28 x 70 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 5–16 mm OD</li><li>Gas Flow Meter: 0–10 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: None/Fixed</li><li>Rotating, Leak Tight Gas Fitting: N/A</li><li>Standard Gas Input Range: 20–30 psig</li><li>Optional Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating (Option Code -RT): Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 5085</li><li>Heating Medium: Aluminum Beads (Glass Beads in RT Models)</li><li>Inside Dimensions (Diameter × Depth): 8.5 × 4.5 in / 21.6 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 13 × 11 × 7 in / 33 × 28 × 18 cm</li><li>Total Wattage: 500 W</li><li>Bath Temperature Range: 40–130 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ± 2 °C</li></ul><h4>12p N-EVAP (No Bath)</h4><ul><li>Bath Type: None</li><li>Instrumental Catalog Number: 11155-O</li><li>Number of Sample Positions: 12</li><li>Overall Dimension (w x d x h): 12 × 8 × 31 in / 33 × 28 × 79 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 5–16 mm OD</li><li>Gas Flow Meter: 0–10 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Optional Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating (Option Code -RT): Optional</li></ul><h3>MODELS</h3><h5>Catalog Number &nbsp;/&nbsp;&nbsp;&nbsp;Bath Type</h5><ul><li>11155: Water Bath</li><li>11155-NT: No Teflon, Water Bath*</li><li>11155-DA: Dry Bath</li><li>11155-O: No Bath</li></ul>* No Teflon (-NT) units designed for PFAS analysis using EPA methods 533, 537 and 537.1. **All “-O” models come with a base and stand assembly instead of a heated bath. These instruments are designed for evaporation procedures performed at ambient temperature.<h3>ACCESSORIES</h3><ul><li>Small vessel sample holder, for vial outside diameters of 5-16 mm (cat# NA1132)</li><li>Nitrogen generator (cat# NA1955)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>Pressure reducing regulator 0-160 psi (cat# NA0630)</li><li>High temperature silicone fluid (cat# NA1240)</li><li>Various needle sizes and gauges</li></ul><h3>REPLACEMENT PARTS</h3><ul><li>P0627: Valve Tube Assembly – Post 1997</li><li>P0607: Luer &amp; washer for N-EVAP valve tube</li><li>P0634: Tube Fitting nylon 3 part for N-EVAP valve tube</li></ul>

Organomation 24 Position N-EVAP Nitrogen Evaporator

The 24 position N-EVAP is our most adaptable benchtop evaporator. The basic model offers all of the standard features from our N-EVAP line. Additionally, the 24 position N-EVAP offers the most customizable options for your sample preparation needs. 

The 24 position N-EVAP is our most adaptable benchtop evaporator. The basic model offers all of the standard features from our N-EVAP line. Additionally, the 24 position N-EVAP offers the most customizable options for your sample preparation needs. The standard sample holder can accommodate samples with an outside diameter of 10-30 mm. However, with the optional 8 position large sample holder, vials with an outside diameter of 30-70 mm can be processed. The 24 position N-EVAP test tube evaporator can also be upgraded to include digital controls for heat and time with the addition of the side control box (Option code -CB).These economical units provide controlled concentration of sample vials through the application of nitrogen gas within a heated water bath. The dual band spring hoist assembly provides a simple and effective means of removing samples from the heated water bath. The N-EVAP’s circular rotating design permits each sample to be accessible from the front of the instrument for easy insertion and retrieval. The chrome plated needle valves are individually milled from solid brass, enabling precise, uniform adjustments for your nitrogen blow down. This promotes efficient and safe sample reduction with minimal nitrogen waste. Time tested technology and proven construction ensure a long lasting, user-friendly experience.<ul><li>Gentle: N-EVAP nitrogen evaporators combine nitrogen blow down with a heated bath to gently concentrate delicate samples</li><li>Flexible: An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li>Customizable: A large sample holder option can be added to accommodate vials with a larger outside diameter up to 70 mm</li><li>Individualized Control: Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_24_Position_N_EVAP_Nitrogen_Evaporator_2_18a854b63f.jpg" alt="Organomation 24 Position N-EVAP Nitrogen Evaporator ." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_24_Position_N_EVAP_Nitrogen_Evaporator_2_18a854b63f.jpg 156w," sizes="100vw" width="1400" height="1400"><h3>STANDARD FEATURES</h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter, 0-20 LPM</li><li>High pressure phthalate free tubing for safety</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly (except in dry bath model)</li><li>Precision needle valve tube assembly</li><li>Needles, 4 inch x 19 gauge with chrome plated brass hub and stainless steel shaft</li></ul><h3>OPTIONS&nbsp;</h3><ul><li>220v wiring harness (Option Code# -2), Cat# 11250-2</li><li>Z-Purge/positive pressure purge case (Option Code# -Z), Cat# 11250-Z</li><li>Acid resistant coating on instrument and needles (Option Code# -RT), Cat# 11250-RT</li><li>Side control box with built-in digital controller, timer, and pressure regulator (Option Code -CB), Cat# 11250-CB</li></ul><h3>SPECS</h3><h4>24 Position N-EVAP (Water Bath)</h4><ul><li>Bath Type: Water</li><li>Instrumental Catalog Number: 11250</li><li>Number of Sample Positions: 24</li><li>Overall Dimension (w × d × h): 16 × 15 × 33 in / 41 × 38 × 84 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 30–70 mm OD</li><li>Gas Flow Meter: 0–20 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating: Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 9125</li><li>Heating Medium: Water</li><li>Inside Dimensions (Diameter × Depth): 12.0 × 4.5 in / 30.5 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 16 × 15 × 7 in / 41 × 38 × 18 cm</li><li>Total Wattage: 900 W</li><li>Bath Temperature Range: 30–90 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ±2 °C</li></ul><h4>24 Position N-EVAP (Dry Bath)</h4><ul><li>Bath Type: Dry</li><li>Instrumental Catalog Number: 11250-DA</li><li>Number of Sample Positions: 24</li><li>Overall Dimension (w × d × h): 16 × 15 × 27.5 in / 41 × 38 × 70 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 30–70 mm OD</li><li>Gas Flow Meter: 0–20 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: None/Fixed</li><li>Rotating, Leak Tight Gas Fitting: N/A</li><li>Standard Gas Input Range: 20–30 psig</li><li>Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating: Optional</li></ul><h5>Heating Device Specs</h5><ul><li>Model Number: 5125</li><li>Heating Medium: Aluminum Beads (Glass Beads in RT Models)</li><li>Inside Dimensions (Diameter × Depth): 12.0 × 4.5 in / 30.5 × 11.4 cm</li><li>Outside Dimensions (w × d × h): 16 × 15 × 7 in / 41 × 38 × 18 cm</li><li>Total Wattage: 540 W</li><li>Bath Temperature Range: 40–130 °C</li><li>Temperature Controller Type: Mechanical Thermostat</li><li>Controller Accuracy: ±2 °C</li></ul><h4>24 Position N-EVAP (No Bath)</h4><ul><li>Bath Type: None</li><li>Instrumental Catalog Number: 11250-O</li><li>Number of Sample Positions: 24</li><li>Overall Dimension (w × d × h): 16 × 15 × 31.75 in / 41 × 38 × 81 cm</li><li>Sample Holder Layout: Circular</li><li>Gas Manifold Layout: Single Ring</li><li>Test Tube Range (Standard Sample Holder): 10–30 mm OD</li><li>Test Tube Range (Optional Sample Holder): 30–70 mm OD</li><li>Gas Flow Meter: 0–20 L/min</li><li>Stainless Steel Needles (Length × Gauge): 4.0 in × 19 ga / 102 mm × 19 ga</li><li>Sample Tray Lift Mechanism: Dual Band Spring Hoist Assembly</li><li>Rotating, Leak Tight Gas Fitting: Standard</li><li>Standard Gas Input Range: 20–30 psig</li><li>Gas Input Range with Optional Pressure Reducing Regulator: 30–160 psig</li><li>Acid Resistant Coating: Optional</li></ul><h3>MODELS</h3><h5>Catalog Number &nbsp;/&nbsp;&nbsp;&nbsp;Bath Type</h5><ul><li>11250: Water Bath</li><li>11250-NT: No Teflon, Water Bath*</li><li>11250-DA: Dry Bath</li><li>11250-O: No Bath**</li></ul>* No Teflon (-NT) units designed for PFAS analysis using EPA methods 533, 537 and 537.1. **All “-O” models come with a base and stand assembly instead of a heated bath. These instruments are designed for evaporation procedures performed at ambient temperature.<h3>ACCESSORIES</h3><ul><li>Large vessel sample holder, 8 positions, for vial outside diameters of 30-70 mm (cat# NA1228)</li><li>Nitrogen generator (cat# NA1955)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>Pressure reducing regulator 0-160 psi (cat# NA0630)</li><li>High temperature silicone fluid (cat# NA1240)</li><li>Various needle sizes and gauges</li></ul><h3>REPLACEMENT PARTS</h3><ul><li>P0627: Valve Tube Assembly – Post 1997</li><li>P0607: Luer &amp; washer for N-EVAP valve tube</li><li>P0634: Tube Fitting nylon 3 part for N-EVAP valve tube</li></ul>

Products focused on Sample Preparation distributed by Organomation - page 2

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