We are excited to announce that registration for the 12th International Symposium on Recent Advances in Food Analysis (RAFA 2026), along with the call for abstracts and travel grants for young scientists, is now officially open!<h3>Key dates</h3><ul><li>May 31, 2026: Application for Young scientist travel grant</li><li>June 30, 2026<ul><li>Application for participation as a Sponsor or Exhibitor or Media partner</li><li>Abstract submission for oral presentation</li><li>Reduced registration fee</li></ul></li><li>August 31, 2026: Abstract submission for poster presentation</li><li>September 30, 2026: Last minute posters submission</li><li>November 3 - 6, 20026: 12th International Symposium on Recent Advances in Food Analysis (RAFA 2026) in Prague, Czech Republic</li></ul><h3>Registration</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://rafa.easyevent.eu/tickets/">Registration for RAFA 2026 is OPEN!</a>Early-bird registration until 30 June, 2026</blockquote>After successful submission of your registration, you will receive by e-mail (i) an automatic confirmation of receipt indicating the total amount of payment due (either for bank transfer or for on-line payment by card), (ii) login to Member section where you can administrate your profile, submit your abstracts, and from September 2026 register for satellite events, workshops and seminars. If it will not be delivered within a few minutes after submission of your registration please contact us at RAFA2026@vscht.cz.As soon as payment of registration fee is processed, you will also receive by e-mail (iii) confirmation of payment.<h4>Important notice:</h4>Registration fee of those who have submitted an abstract for oral or poster presentation has to be received until September 30, 2026, otherwise these contribution(s) will not be included into the Book of Abstracts and the Conference programme.<h4>Registration Fees</h4><ul><li>Smart rate (Until 30 June, 2026): € 655</li><li>Regular registration (Until 30 September, 2026): € 855</li><li>Late registration (From 1 October, 2026): € 955</li><li>Student rate*&nbsp;<ul><li>Until 30 June, 2026: € 465</li><li>From 1 July, 2026: € 605</li></ul></li></ul>* The proof of student status (e.g. copy of a student identify card) is requested as an attachment of the registration form.<h5>The regular registration fee will include:</h5><ul><li>Attendance at all scientific sessions, workshops, seminars, vendor seminars and other satellite events</li><li>Access to the poster and exhibition area</li><li>Conference kit (name badge, conference bag, conference documents, certificate of participation, certificate of presentation on request)</li><li>Final programme</li><li>E-Book of Abstracts</li><li>Coffee breaks</li><li>Buffet luncheons</li><li>Welcome drink</li></ul>In the registration form you can register free of charge for the welcome drink and you can also order ticket(s) for the conference dinner (€ 85).Please note that your registration is firm when your payment has been received.<h3>Abstract submission</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://rafa.easyevent.eu/tickets/">CALL for ABSTRACTS is OPEN!</a>In order to submit an abstract, you must first register to attend RAFA 2026. After registration you will receive an access to the Member section where you can submit your abstract(s).</blockquote>&nbsp;After successful submission of your abstract you will receive an automatic confirmation of receipt of submitted abstract via e-mail. If it will not be delivered within a few minutes after submission of your abstract please check at first your spam box-mail and then contact us at RAFA2026@vscht.cz.Please ensure that your abstract does not contain spelling, grammatical or scientific errors. Even though modifications of your submitted abstract will be allowed in the Abstract section of the Member section until the deadline for the abstract submission, please be confident on the lack of errors in your final version prior to starting the submission process.The abstract will be reproduced exactly as submitted. No proofreading will be done, although some corrections may be requested by the reviewers.If you need to withdraw your abstract, a written statement reflecting the reasons for this decision must be sent to RAFA2026@vscht.cz no later than September 30, 2026.<h4>Important notice:</h4><blockquote>1 registered participant can submit no more than 2 abstracts.</blockquote>To apply for a young scientist’s oral presentation, as an indication please respect the rule that you should be born in 1991 or later.The text of the abstract should be limited to 3000 characters including spaces. Tables and pictures are not allowed.Abstracts of oral presentations and posters will be included into the "e-Book of Abstracts" only after receipt of the conference registration fee. Any payment of the registration fee has to be received until September 30, 2026, otherwise contribution(s) will not be included into the e-Book of Abstracts and the Conference programme.<h3>Special opportunities for young scientists:</h3><ul><li>Dedicated slots for oral presentations within the main scientific programme</li><li>Competitive travel grants for young scientists</li><li>Award(s) for the best poster presentation(s)</li></ul>Whether you are a PhD student or an early-career researcher, RAFA 2026 offers a unique opportunity to present your work, gain international exposure and connect with leading experts in the field.Be part of this inspiring scientific event and join us in Prague!

RAFA 2026 - Registration & Call for Abstracts are now OPEN

44th International Symposium on Capillary Chromatography - Invited speakers

In analytical chemistry, there are moments when your instrument gives you an answer, and moments when it gives you a question. The difference often comes down to resolution.A compelling example can be found in the analysis of blue fenugreek (Trigonella caerulea), a plant that is widely used as a spice in traditional foods. Interestingly, the fresh plant has almost no aroma, yet after drying and storage it develops a rich and complex bouquet. Understanding this transformation requires detailed insight into a highly dynamic mixture of volatile compounds.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Aromatic_profiling_using_GCMS_and_HRGCMS_5a89d505be.jpg" alt="Thermo Fisher Scientific: When Resolution Changes the Story: Single Quadrupole vs. HRAM GC-MS" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Aromatic_profiling_using_GCMS_and_HRGCMS_5a89d505be.jpg 234w," sizes="100vw" width="1280" height="853">When researchers investigated this system using <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/484">GC-MS</a>, they encountered exactly the kind of analytical ambiguity that many of us are familiar with. The sample contained a complex mixture of aldehydes and monoterpenoids, along with compounds that were not well described in existing databases.At first glance, a single quadrupole GC-MS appears to be perfectly suited for this type of analysis. It is robust, widely available, and highly effective for routine workflows. It provides reproducible fragmentation patterns and enables reliable library matching. In many cases, this is entirely sufficient.However, challenges arise when compounds share very similar fragmentation behavior. In the case of blue fenugreek, one particular signal could be interpreted in more than one way. The data were consistent with either dimethyl sulfide or a sulfine-type compound. Both possibilities made chemical sense, and both could be supported by the spectra obtained on a quadrupole system.This situation illustrates a fundamental limitation of unit mass resolution. When two candidate structures produce nearly indistinguishable spectra, the instrument cannot decisively distinguish between them. The result is not an incorrect answer, but an incomplete one. You are left with a hypothesis rather than a conclusion.The picture changes significantly when high-resolution accurate mass <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/473">(HRAM) GC-MS</a> is introduced. Instruments such as Orbitrap-based systems provide exact mass measurements with very high accuracy. This allows the determination of elemental compositions and enables clear differentiation between compounds that differ only slightly in mass.In the same example, HRAM analysis made it possible to distinguish between the competing structural hypotheses. What previously appeared ambiguous could now be resolved with confidence.This improvement is not merely a technical detail. It has important consequences for how the data are interpreted. Correct compound identification directly affects our understanding of biochemical pathways, especially in systems where aroma compounds are formed during drying and storage. It also influences how we assign sensory properties, since even small structural differences can lead to significant changes in odor perception. Furthermore, when studying the dynamics of volatile compounds over time, precise identification becomes essential for tracking formation and degradation processes.Despite these advantages, it would be misleading to suggest that HRAM GC-MS should replace single quadrupole systems in all cases. Single quadrupole instruments remain indispensable for routine analysis, targeted workflows, and situations where compounds are well known and thoroughly characterized. They offer a practical balance of performance, cost, and throughput.The key distinction lies in the analytical question being asked. If the goal is to quantify known compounds in a reliable and efficient manner, a single quadrupole system is often entirely appropriate. If, however, the goal is to identify unknowns, resolve ambiguities, or explore complex and poorly understood systems, then high-resolution accurate mass becomes essential.The study of blue fenugreek highlights a broader lesson. Natural products often present us with chemical complexity that challenges our assumptions and our tools. In such cases, ambiguity in the data is not a failure, but an indication that a deeper level of analysis is required.Ultimately, resolution is more than just an instrument specification. It defines how confidently we can translate signals into knowledge.<h4>Acknowledgement:</h4>I would like to thank Dr. Thomas Stegemann, Lab Manager and group leader, Christian-Alberts-University, Kiel, for the contribution to this blog.<h4>Call to action:</h4><ul><li>Watch webinar on demand: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6020">Aromatic profiling using GCMS and HRGCMS</a></li><li>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#GCMS #MassSpectrometry #HRAM #Orbitrap</li></ul><blockquote><h5>Petra Gerhards</h5>Regional Marketing Manager GC and GC/MS, EMEA, Thermo Fisher Scientific&nbsp;</blockquote>

When Resolution Changes the Story: Single Quadrupole vs. HRAM GC-MS

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Food

RAFA provides an overview of contemporary trends in ANALYTICAL & BIOANALYTICAL STRATEGIES IN FOOD QUALITY AND SAFETY CONTROL and discusses CHALLENGES / NOVEL APPROACHES IN FOOD AND NATURAL PRODUCTS ANALYSIS.

Recent Advances in Food Analysis (RAFA)

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

ISCC & GC×GC Symposium bring together global experts to discuss advances in capillary and multidimensional chromatography, mass spectrometry, and analytical technologies for complex sample analysis.

International Symposium on Capillary Chromatography (ISCC) and GCxGC Symposium

Organomation NiGen GC/HC Nitrogen Generator

The NiGen GC/HC is available in both a basic and HC version which completely removes hydrocarbons using a Pt/Pd catalyzer. 

The NiGen GC/HC is available in both a basic and HC version which completely removes hydrocarbons using a Pt/Pd catalyzer. It is capable of distributing 500 mL/min with greater than 99.9995% purity. It's designed to be connected to a dedicated AirComp compressor (can be purchased separately).&nbsp;Parallel connection allows for up to 4 generators to be stacked in a tower configuration. It features a CPU with touch screen display, which can be linked to a generator using CAN-BUS. This enables monitoring of the operating status and provides access to the maintenance menu, alarm reports, and functional parameters. It is capable of supporting up to 12 FIDs or NPDs with makeup gas or up to 7 ECDs.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_Ni_Gen_GC_modular_configuration_75ae60afb0.jpg" alt="Organomation: NiGen GC - Modular configuration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_Ni_Gen_GC_modular_configuration_75ae60afb0.jpg 147w," sizes="100vw" width="727" height="768"><h4>Standard features</h4><ul><li>Modular configuration</li><li>Capacity to supply up to 12 FIDs/NPDs with makeup gas, or up to 7 ECDs or 5 S/S</li><li>Easy, "plug and play" integration with the dedicated Brezza series air compressor AirComp</li><li>Included Fast Start technology guarantees UHP after only 30 minutes</li><li>HC model includes Pt/Pd to remove up to .1ppm of THC</li><li>CPU with Touch Screen Display (connectable with CAN BUS) allows you to monitor the operational status</li><li>CPU also has an Ethernet output for PC connection&nbsp;</li></ul><h4>Specification</h4>Key Features:<ul><li>Flow Rate: 500 mL/min</li><li>Output Pressure: 0 – 87 PSI (0 – 6 bar)</li><li>Purity: &gt; 99.9995%</li><li>Total Hydrocarbons: &lt; 0.1 ppm (HC model only)</li></ul>Air Input Requirements:<ul><li>Particulates: ≤ 0.01 mm</li><li>Oil Vapors: ≤ 0.01 mg/m³</li><li>Moisture: ≤ 3 °C dew point (ATP)</li><li>Minimum Pressure: 8 bar</li><li>Flow Rate: 6 L/min</li></ul>Electrical Requirements:<ul><li>NiGen GC: 115/230 V ±10%, 50–60 Hz, 50 W</li><li>NiGen GC HC:<ul><li>115 V ±10%, 60 Hz, 200 W</li><li>230 V ±10%, 50 Hz, 200 W</li></ul></li></ul>Additional Specifications:<ul><li>Protection Index: IP20</li><li>Noise Level:<ul><li>&lt; 50 dBA for 98% of operation</li><li>&lt; 60 dBA briefly during cycling</li></ul></li><li>Operating Temperature: 40 °F to 100 °F (5 °C to 40 °C)</li><li>Environmental Humidity: Max 90% (non-condensing)</li><li>Maximum Altitude: 2000 m (6561.68 ft)</li></ul>Dimensions &amp; Weight:<ul><li>GC Model:<ul><li>Height: 15.8" (40 cm)</li><li>Weight: 63 lbs (28 kg)</li></ul></li><li>GC HC Model:<ul><li>Height: 18.6" (47 cm)</li><li>Weight: 70.5 lbs (32 kg)</li></ul></li><li>Width: 14.9" (38 cm)</li><li>Depth: 20.8" (53 cm)</li></ul>Pneumatic Connections:<ul><li>Compressed Air Inlet: G 1/8” female</li><li>Nitrogen Outlet: G 1/8” female</li></ul>Warranty: 2 years<h4>Accessories</h4><ul><li>AirComp oil free compressor</li><li>CPU: User interface with touch screen display Brezza version</li><li>Installation kit</li><li>Maintenance kit for 8,000 or 16,000 running hours</li></ul>

Organomation NITRO-GEN Nitrogen Generator

The NITRO-GEN generator was developed with Organomation’s nitrogen evaporators in mind to provide nitrogen generation for sample concentration.

The NITRO-GEN generator was developed with Organomation’s nitrogen evaporators in mind to provide nitrogen generation for sample concentration. The generator is lightweight and easy to set up, requiring only a source of compressed air to run. This unit is an ideal choice for labs with an in-house compressed air source.The generator uses a hollow-fiber membrane to convert compressed air to a stream of 95-99% pure nitrogen gas. The hollow-fiber membrane consists of a series of narrow, semipermeable tubes in a porous membrane. As compressed air travels through the fibers, oxygen and water vapor permeate the membrane and are vented off, leaving a steam of high purity nitrogen gas. At up to 99% purity, the resulting nitrogen gas stream can be used in a variety of sample preparation applications.<h4>NITRO-GEN</h4>The NITRO-GEN produces up to 20 L/min of nitrogen gas and is recommended for evaporation of up to 48 sample positions.&nbsp;<h4>Standard features</h4><ul><li>Adjustable outlet pressure regulator, 0-100 psi</li><li>Dual Stage clean air filtration system</li><li>Requires an oil-less compressed air source</li></ul><h4>Advantages</h4><ul><li>Quick Start-Up Time - Nitrogen is produced instantly, no heat up time</li><li>Saves Energy - No electrical power needed</li><li>Engineered Design - Life expectancy is more than 10 years</li><li>Low Maintenance - Serviceable clean air filter</li><li>Compact and Lightweight - Small footprint conserves valuable bench space</li><li>Reduced CO2 Emissions - No heaters, less energy required</li></ul><h4>Specification</h4><h5>Key Features:</h5><ul><li>Flow Rate: Up to 20 L/min</li><li>Technology: Hollow-fiber membrane</li><li>Output Pressure: Adjustable 0 – 100 PSI</li><li>Electrical Requirements: None (no power required)</li><li>Noise Level: &lt; 40 dBA (virtually silent when connected to an instrument)</li></ul><h5>Inlet Air Requirements:</h5><ul><li>Maximum Inlet Pressure: 150 PSI (10.3 bar)</li><li>Particulate Filtration: ≤ 0.01 µm</li><li>Oil Vapor Content: &lt; 0.01 mg/m³ (&lt; 0.01 ppm)</li><li>Relative Humidity: &lt; 100% (non-condensing)</li><li>Air Quality: Clean, contaminant-free air</li></ul><h5>Environmental Conditions:</h5><ul><li>Operating Temperature: 36–122 °F (2–50 °C)</li><li>Ambient Pressure: Atmospheric</li></ul><h5>Dimensions &amp; Weight:</h5><ul><li>Size (W × D × H): 9.5 × 8 × 19.5 in (241 × 203 × 495 mm)</li><li>Weight: 13.25 lbs (6 kg)</li></ul>Warranty: 1 year

Linde REDLINE Pressure Regulators C 200/1 & C 200/2

REDLINE C 200 pressure regulators provide precise and stable gas control up to 6.0 purity, ideal for laboratory, analytical, and research applications.

The REDLINE C 200 series pressure regulators (models C 200/1 single-stage and C 200/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.These regulators ensure excellent pressure stability, high accuracy, and preservation of gas purity, making them ideal for demanding laboratory, analytical, and research applications.The C 200/1 single-stage version is suitable for applications with stable inlet pressure, such as gases supplied in liquid phase. The C 200/2 dual-stage version is specifically designed for systems where inlet pressure fluctuates, ensuring highly stable outlet pressure even under changing conditions.<h4>Key Features</h4><ul><li>High precision pressure regulation for analytical applications</li><li>Suitable for high-purity gases up to grade 6.0 (99.9999%)</li><li>Excellent outlet pressure stability (especially dual-stage version)</li><li>Designed to maintain gas purity and minimize contamination</li><li>Wide range of configurable outlet pressure ranges</li><li>Flexible configuration with multiple valve and purging options</li><li>Robust and reliable design for laboratory and R&amp;D environments</li></ul><h4>Technical Specifications</h4><ul><li>Inlet pressure: up to 230 bar</li><li>Outlet pressure ranges:<ul><li>C 200/1 (single-stage): 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li>C 200/2 (dual-stage): 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li>Gas compatibility:<ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li>Inlet connections:<ul><li>According to DIN 477 and gas specification</li></ul></li><li>Outlet connections:<ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4>Available Configurations</h4><h5>Models</h5><ul><li>C 200/1 (Single-stage) Designed for applications with stable inlet pressure</li><li>C 200/2 (Dual-stage) Designed for fluctuating inlet pressure with maximum outlet stability</li></ul><h4>Optional Equipment</h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert/external gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 200/2)</li></ul><h4>Applications</h4><ul><li>Laboratory gas supply systems</li><li>Analytical instrumentation (e.g., GC, LC, MS workflows)</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Any application requiring stable pressure and contamination-free gas delivery</li></ul>

Linde REDLINE Pressure Regulators C 300/1 & C 300/2

REDLINE C 300 pressure regulators provide precise and stable gas control up to 6.0 purity, ensuring reliability for laboratory, analytical, and research applications.

The REDLINE C 300 series pressure regulators (models C 300/1 single-stage and C 300/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.Thanks to their robust design and high-quality manufacturing, these regulators provide excellent pressure stability, accuracy, and long-term reliability. They are particularly well suited for demanding laboratory, analytical, and research applications where maintaining gas purity and consistent pressure is critical.The C 300/1 single-stage regulator is recommended for applications with relatively stable inlet pressure, such as gases supplied in liquid phase. The C 300/2 dual-stage version is intended for systems with fluctuating inlet pressure, ensuring highly stable outlet pressure and improved control under varying operating conditions.<h4>Key Features</h4><ul><li>Precise and stable pressure regulation for analytical workflows</li><li>Compatible with high-purity gases up to grade 6.0 (99.9999%)</li><li>Dual-stage version provides superior outlet pressure stability</li><li>Designed to maintain gas purity and minimize contamination risks</li><li>Wide range of adjustable outlet pressure settings</li><li>Modular design with multiple optional valve and purge configurations</li><li>High reliability for continuous laboratory and R&amp;D operation</li></ul><h4>Technical Specifications</h4><ul><li>Inlet pressure: up to 300 bar</li><li>Outlet pressure ranges:<ul><li>C 300/1 (single-stage): 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li>C 300/2 (dual-stage): 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li>Gas compatibility:<ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li>Inlet connections:<ul><li>According to DIN 477 and gas specification</li></ul></li><li>Outlet connections:<ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4>Available Configurations</h4><h5>Models</h5><ul><li>C 300/1 (Single-stage) Designed for applications with stable inlet pressure</li><li>C 300/2 (Dual-stage) Designed for fluctuating inlet pressure with maximum outlet pressure stability</li></ul><h4>Optional Equipment</h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 300/2)</li></ul><h4>Applications</h4><ul><li>Analytical instrumentation (e.g., GC, LC, MS systems)</li><li>Laboratory gas supply systems</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Applications requiring precise pressure control and contamination-free gas delivery</li></ul>

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When Resolution Changes the Story: Single Quadrupole vs. HRAM GC-MS

44th International Symposium on Capillary Chromatography - Invited speakers

RAFA 2026 - Registration & Call for Abstracts are now OPEN